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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: CD164 (CAeditome ID:8763)

Gene summary for CD164

check button Gene summary
Gene informationGene symbol

CD164

Gene ID

8763

Gene nameCD164 molecule
SynonymsDFNA66|MGC-24|MGC-24v|MUC-24|endolyn
Cytomap

6q21

Type of geneprotein-coding
Descriptionsialomucin core protein 24CD164 antigen, sialomucinmulti-glycosylated core protein 24
Modification date20210518
UniProtAcc

Q04900

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
CD164

GO:0007155

Sialomucin core protein 24

10491205

CD164

GO:0007157

Sialomucin core protein 24

10491205

CD164

GO:0005764

Sialomucin core protein 24

11027692

CD164

GO:0005768

Sialomucin core protein 24

11027692

CD164

GO:0005768

Sialomucin core protein 24

26197441

CD164

GO:0005886

Sialomucin core protein 24

10491205

CD164

GO:0005886

Sialomucin core protein 24

26197441


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RNA A-to-I events for CD164

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000135535.13
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_499252(109371315, -), CAediting_499253(109371318, -), CAediting_499254(109371347, -), CAediting_499255(109371348, -), CAediting_499256(109371359, -), CAediting_499257(109371388, -), CAediting_499258(109371389, -), CAediting_499259(109371415, -), CAediting_499260(109371428, -), CAediting_499261(109371451, -), CAediting_499262(109371468, -), CAediting_499263(109371469, -), CAediting_499264(109371482, -), CAediting_499265(109371492, -), CAediting_499266(109371499, -), CAediting_499267(109371500, -), CAediting_499268(109371516, -), CAediting_499269(109371521, -), CAediting_499270(109371522, -), CAediting_499271(109371534, -), CAediting_499272(109371560, -), CAediting_499273(109371568, -), CAediting_499274(109371589, -), CAediting_499275(109372540, -), CAediting_499276(109372550, -), CAediting_499277(109372557, -), CAediting_499278(109372572, -), CAediting_499279(109372608, -), CAediting_499280(109372618, -), CAediting_499281(109372629, -), CAediting_499282(109372631, -), CAediting_499283(109372638, -), CAediting_499284(109372639, -), CAediting_499285(109372643, -), CAediting_499286(109372645, -), CAediting_499287(109372654, -), CAediting_499288(109372673, -), CAediting_499289(109372679, -), CAediting_499290(109372691, -), CAediting_499291(109372692, -), CAediting_499292(109372696, -), CAediting_499293(109372697, -), CAediting_499294(109375200, -), CAediting_499295(109375298, -), CAediting_499296(109375302, -), CAediting_499297(109375307, -), CAediting_499298(109375319, -), CAediting_499299(109375360, -), CAediting_499300(109375382, -), CAediting_499301(109375399, -), CAediting_499302(109375411, -), CAediting_499303(109375412, -), CAediting_499304(109375425, -), CAediting_499305(109375432, -), CAediting_499306(109375437, -), CAediting_499307(109375469, -), CAediting_499308(109375489, -), CAediting_499309(109375495, -), CAediting_499310(109375534, -), CAediting_499311(109375540, -), CAediting_499312(109375541, -), CAediting_499313(109375560, -), CAediting_499314(109375573, -),

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RNA editing positional annotations for CD164 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_499252chr6_109371315_-ncRNA_exonic
CAediting_499253chr6_109371318_-ncRNA_exonic
CAediting_499254chr6_109371347_-ncRNA_exonic
CAediting_499255chr6_109371348_-ncRNA_exonic
CAediting_499256chr6_109371359_-ncRNA_exonic
CAediting_499257chr6_109371388_-ncRNA_exonic
CAediting_499258chr6_109371389_-ncRNA_exonic
CAediting_499259chr6_109371415_-ncRNA_exonic
CAediting_499260chr6_109371428_-ncRNA_exonic
CAediting_499261chr6_109371451_-ncRNA_exonic
CAediting_499262chr6_109371468_-ncRNA_exonic
CAediting_499263chr6_109371469_-ncRNA_exonic
CAediting_499264chr6_109371482_-ncRNA_exonic
CAediting_499265chr6_109371492_-ncRNA_exonic
CAediting_499266chr6_109371499_-ncRNA_exonic
CAediting_499267chr6_109371500_-ncRNA_exonic
CAediting_499268chr6_109371516_-ncRNA_exonic
CAediting_499269chr6_109371521_-ncRNA_exonic
CAediting_499270chr6_109371522_-ncRNA_exonic
CAediting_499271chr6_109371534_-ncRNA_exonic
CAediting_499272chr6_109371560_-ncRNA_exonic
CAediting_499273chr6_109371568_-ncRNA_exonic
CAediting_499274chr6_109371589_-ncRNA_exonic
CAediting_499275chr6_109372540_-ncRNA_exonic
CAediting_499276chr6_109372550_-ncRNA_exonic
CAediting_499277chr6_109372557_-ncRNA_exonic
CAediting_499278chr6_109372572_-ncRNA_exonic
CAediting_499279chr6_109372608_-ncRNA_exonic
CAediting_499280chr6_109372618_-ncRNA_exonic
CAediting_499281chr6_109372629_-ncRNA_exonic
CAediting_499282chr6_109372631_-ncRNA_exonic
CAediting_499283chr6_109372638_-ncRNA_exonic
CAediting_499284chr6_109372639_-ncRNA_exonic
CAediting_499285chr6_109372643_-ncRNA_exonic
CAediting_499286chr6_109372645_-ncRNA_exonic
CAediting_499287chr6_109372654_-ncRNA_exonic
CAediting_499288chr6_109372673_-ncRNA_exonic
CAediting_499289chr6_109372679_-ncRNA_exonic
CAediting_499290chr6_109372691_-ncRNA_exonic
CAediting_499291chr6_109372692_-ncRNA_exonic
CAediting_499292chr6_109372696_-ncRNA_exonic
CAediting_499293chr6_109372697_-ncRNA_exonic
CAediting_499294chr6_109375200_-ncRNA_intronic
CAediting_499295chr6_109375298_-ncRNA_intronic
CAediting_499296chr6_109375302_-ncRNA_intronic
CAediting_499297chr6_109375307_-ncRNA_intronic
CAediting_499298chr6_109375319_-ncRNA_intronic
CAediting_499299chr6_109375360_-ncRNA_intronic
CAediting_499300chr6_109375382_-ncRNA_intronic
CAediting_499301chr6_109375399_-ncRNA_intronic
CAediting_499302chr6_109375411_-ncRNA_intronic
CAediting_499303chr6_109375412_-ncRNA_intronic
CAediting_499304chr6_109375425_-ncRNA_intronic
CAediting_499305chr6_109375432_-ncRNA_intronic
CAediting_499306chr6_109375437_-ncRNA_intronic
CAediting_499307chr6_109375469_-ncRNA_intronic
CAediting_499308chr6_109375489_-ncRNA_intronic
CAediting_499309chr6_109375495_-ncRNA_intronic
CAediting_499310chr6_109375534_-ncRNA_intronic
CAediting_499311chr6_109375540_-ncRNA_intronic
CAediting_499312chr6_109375541_-ncRNA_intronic
CAediting_499313chr6_109375560_-ncRNA_intronic
CAediting_499314chr6_109375573_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_499252chr6_109371315_-SINEAluAluSz
CAediting_499253chr6_109371318_-SINEAluAluSz
CAediting_499254chr6_109371347_-SINEAluAluSz
CAediting_499255chr6_109371348_-SINEAluAluSz
CAediting_499256chr6_109371359_-SINEAluAluSz
CAediting_499257chr6_109371388_-SINEAluAluSz
CAediting_499258chr6_109371389_-SINEAluAluSz
CAediting_499259chr6_109371415_-SINEAluAluSz
CAediting_499260chr6_109371428_-SINEAluAluSz
CAediting_499261chr6_109371451_-SINEAluAluSz
CAediting_499262chr6_109371468_-SINEAluAluSz
CAediting_499263chr6_109371469_-SINEAluAluSz
CAediting_499264chr6_109371482_-SINEAluAluSz
CAediting_499265chr6_109371492_-SINEAluAluSz
CAediting_499266chr6_109371499_-SINEAluAluSz
CAediting_499267chr6_109371500_-SINEAluAluSz
CAediting_499268chr6_109371516_-SINEAluAluSz
CAediting_499269chr6_109371521_-SINEAluAluSz
CAediting_499270chr6_109371522_-SINEAluAluSz
CAediting_499271chr6_109371534_-SINEAluAluSz
CAediting_499294chr6_109375200_-LINEL1L1M5
CAediting_499299chr6_109375360_-SINEAluAluSx1
CAediting_499300chr6_109375382_-SINEAluAluSx1
CAediting_499301chr6_109375399_-SINEAluAluSx1
CAediting_499302chr6_109375411_-SINEAluAluSx1
CAediting_499303chr6_109375412_-SINEAluAluSx1
CAediting_499304chr6_109375425_-SINEAluAluSx1
CAediting_499305chr6_109375432_-SINEAluAluSx1
CAediting_499306chr6_109375437_-SINEAluAluSx1
CAediting_499307chr6_109375469_-SINEAluAluSx1
CAediting_499308chr6_109375489_-SINEAluAluSx1
CAediting_499309chr6_109375495_-SINEAluAluSx1
CAediting_499310chr6_109375534_-SINEAluAluSx1
CAediting_499311chr6_109375540_-SINEAluAluSx1
CAediting_499312chr6_109375541_-SINEAluAluSx1
CAediting_499313chr6_109375560_-SINEAluAluSx1
CAediting_499314chr6_109375573_-SINEAluAluSx1

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RNA A-to-I editing events in the alternative splicing sites for CD164

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_499307chr6_109375469_-109375450:1093754723SS0+17iACTAATTTTTGTTTTTTTAGTAG5.88ACTGATTTTTGTTTTTTTAGTAG6.28
ESCAediting_499307chr6_109375469_-109375447:1093754693SS0+20iAATTTTTGTTTTTTTAGTAGAGT3.79GATTTTTGTTTTTTTAGTAGAGT4
IRCAediting_499307chr6_109375469_-109375447:1093754693SS0+20iAATTTTTGTTTTTTTAGTAGAGT3.79GATTTTTGTTTTTTTAGTAGAGT4
IRCAediting_499307chr6_109375469_-109375450:1093754723SS0+17iACTAATTTTTGTTTTTTTAGTAG5.88ACTGATTTTTGTTTTTTTAGTAG6.28
MEX_2CAediting_499307chr6_109375469_-109375450:1093754723SS0+17iACTAATTTTTGTTTTTTTAGTAG5.88ACTGATTTTTGTTTTTTTAGTAG6.28

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000135535.13.CD164.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000135535.13.CD164.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CD164

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CD164

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CD164

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1229413chr17_67471544_+ENSG00000135535.13ENST00000413644hsa-miR-548aa1093675861093675927mer-m8109367585109367609140-7.83
CAediting_228905chr2_188297554_+ENSG00000135535.13ENST00000413644hsa-miR-561-3p1093673141093673207mer-m8109367313109367332141-13.92
CAediting_1229413chr17_67471544_+ENSG00000135535.13ENST00000324953hsa-miR-548aa1093675861093675927mer-m8109367585109367609140-7.83
CAediting_228905chr2_188297554_+ENSG00000135535.13ENST00000324953hsa-miR-561-3p1093673141093673207mer-m8109367313109367332141-13.92
CAediting_1229413chr17_67471544_+ENSG00000135535.13ENST00000275080hsa-miR-548aa1093675861093675927mer-m8109367585109367609140-7.83
CAediting_228905chr2_188297554_+ENSG00000135535.13ENST00000275080hsa-miR-561-3p1093673141093673207mer-m8109367313109367332141-13.92

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688081chr9_63819627_+ENSG00000135535.13ENST00000324953hsa-miR-4477b1093685791093685857mer-m8109368578109368599142-8.28
CAediting_688081chr9_63819627_+ENSG00000135535.13ENST00000275080hsa-miR-4477b1093685791093685857mer-m8109368578109368599142-8.28

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CD164

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000415861.2retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_499252ENST00000415861.2chr6_109371315_--1204.70-1199.50-1238.60
CAediting_499253ENST00000415861.2chr6_109371318_--1199.80-1199.50-1238.60
CAediting_499254ENST00000415861.2chr6_109371347_--1200.30-1199.50-1238.60
CAediting_499255ENST00000415861.2chr6_109371348_--1199.50-1199.50-1238.60
CAediting_499256ENST00000415861.2chr6_109371359_--1205.40-1199.50-1238.60
CAediting_499257ENST00000415861.2chr6_109371388_--1199.40-1199.50-1238.60
CAediting_499258ENST00000415861.2chr6_109371389_--1199.10-1199.50-1238.60
CAediting_499259ENST00000415861.2chr6_109371415_--1199.20-1199.50-1238.60
CAediting_499260ENST00000415861.2chr6_109371428_--1199.50-1199.50-1238.60
CAediting_499261ENST00000415861.2chr6_109371451_--1202.40-1199.50-1238.60
CAediting_499262ENST00000415861.2chr6_109371468_--1201.40-1199.50-1238.60
CAediting_499263ENST00000415861.2chr6_109371469_--1199.50-1199.50-1238.60
CAediting_499264ENST00000415861.2chr6_109371482_--1200.50-1199.50-1238.60
CAediting_499265ENST00000415861.2chr6_109371492_--1201.70-1199.50-1238.60
CAediting_499266ENST00000415861.2chr6_109371499_--1200.30-1199.50-1238.60
CAediting_499267ENST00000415861.2chr6_109371500_--1200.60-1199.50-1238.60
CAediting_499268ENST00000415861.2chr6_109371516_--1199.60-1199.50-1238.60
CAediting_499269ENST00000415861.2chr6_109371521_--1199.80-1199.50-1238.60
CAediting_499270ENST00000415861.2chr6_109371522_--1202.50-1199.50-1238.60
CAediting_499271ENST00000415861.2chr6_109371534_--1200.60-1199.50-1238.60
CAediting_499272ENST00000415861.2chr6_109371560_--1199.20-1199.50-1238.60
CAediting_499273ENST00000415861.2chr6_109371568_--1199.20-1199.50-1238.60
CAediting_499274ENST00000415861.2chr6_109371589_--1206.10-1199.50-1238.60
CAediting_499275ENST00000415861.2chr6_109372540_--1199.10-1199.50-1238.60
CAediting_499276ENST00000415861.2chr6_109372550_--1198.80-1199.50-1238.60
CAediting_499277ENST00000415861.2chr6_109372557_--1199.50-1199.50-1238.60
CAediting_499278ENST00000415861.2chr6_109372572_--1198.80-1199.50-1238.60
CAediting_499279ENST00000415861.2chr6_109372608_--1198.70-1199.50-1238.60
CAediting_499280ENST00000415861.2chr6_109372618_--1199.20-1199.50-1238.60
CAediting_499281ENST00000415861.2chr6_109372629_--1199.50-1199.50-1238.60
CAediting_499282ENST00000415861.2chr6_109372631_--1199.50-1199.50-1238.60
CAediting_499283ENST00000415861.2chr6_109372638_--1202.30-1199.50-1238.60
CAediting_499284ENST00000415861.2chr6_109372639_--1201.50-1199.50-1238.60
CAediting_499285ENST00000415861.2chr6_109372643_--1202.30-1199.50-1238.60
CAediting_499286ENST00000415861.2chr6_109372645_--1203.00-1199.50-1238.60
CAediting_499287ENST00000415861.2chr6_109372654_--1200.60-1199.50-1238.60
CAediting_499288ENST00000415861.2chr6_109372673_--1200.10-1199.50-1238.60
CAediting_499289ENST00000415861.2chr6_109372679_--1202.10-1199.50-1238.60
CAediting_499290ENST00000415861.2chr6_109372691_--1200.20-1199.50-1238.60
CAediting_499291ENST00000415861.2chr6_109372692_--1199.60-1199.50-1238.60
CAediting_499292ENST00000415861.2chr6_109372696_--1199.50-1199.50-1238.60
CAediting_499293ENST00000415861.2chr6_109372697_--1200.50-1199.50-1238.60

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Relation with ADAR for CD164

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for CD164

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for CD164

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for CD164

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CD164

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
CD164C0000786Spontaneous abortion1CTD_human
CD164C0000822Abortion, Tubal1CTD_human
CD164C3711374Nonsyndromic Deafness1CLINGEN
CD164C3830362Early Pregnancy Loss1CTD_human
CD164C4283893DEAFNESS, AUTOSOMAL DOMINANT 661CLINGEN;CTD_human;GENOMICS_ENGLAND
CD164C4552766Miscarriage1CTD_human