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Editing gene: CDS2 (CAeditome ID:8760)

Gene summary for CDS2

Gene summary

Gene information	Gene symbol	CDS2
	Gene ID	8760
	Gene name	CDP-diacylglycerol synthase 2
	Synonyms	-
	Cytomap	20p12.3
	Type of gene	protein-coding
	Description	phosphatidate cytidylyltransferase 2CDP-DAG synthase 2CDP-DG synthase 2CDP-DG synthetase 2CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2CDP-diglyceride diphosphorylase 2CDP-diglyceride pyrophosphorylase 2CDP-diglyceride synthase
	Modification date	20210518
	UniProtAcc	O95674
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
CDS2	GO:0004605	Phosphatidate cytidylyltransferase 2	25375833
CDS2	GO:0016024	Phosphatidate cytidylyltransferase 2	25375833
CDS2	GO:0005783	Phosphatidate cytidylyltransferase 2	25375833
CDS2	GO:0005783	Phosphatidate cytidylyltransferase 2	26946540
CDS2	GO:0005783	Phosphatidate cytidylyltransferase 2	31548309

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RNA A-to-I events for CDS2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000101290.12

RNA A-to-I editing events in Cancer.

CAediting_1404062(5128524, +), CAediting_1404063(5128525, +), CAediting_1404064(5128537, +), CAediting_1404065(5128551, +), CAediting_1404066(5129543, +), CAediting_1404067(5129572, +), CAediting_1404068(5129622, +), CAediting_1404069(5129625, +), CAediting_1404070(5129662, +), CAediting_1404071(5129670, +), CAediting_1404072(5129790, +), CAediting_1404073(5130034, +), CAediting_1404074(5130689, +), CAediting_1404075(5130770, +), CAediting_1404076(5130837, +), CAediting_1404077(5130872, +), CAediting_1404078(5130880, +), CAediting_1404079(5130914, +), CAediting_1404080(5130999, +), CAediting_1404081(5131021, +), CAediting_1404082(5132237, +), CAediting_1404083(5133050, +), CAediting_1404084(5133060, +), CAediting_1404085(5133064, +), CAediting_1404086(5133095, +), CAediting_1404087(5133096, +), CAediting_1404088(5133116, +), CAediting_1404089(5133120, +), CAediting_1404090(5133283, +), CAediting_1404091(5133331, +), CAediting_1404092(5133394, +), CAediting_1404093(5134590, +), CAediting_1404094(5134660, +), CAediting_1404095(5134718, +), CAediting_1404096(5134721, +), CAediting_1404097(5137478, +), CAediting_1404098(5138493, +), CAediting_1404099(5138585, +), CAediting_1404100(5138612, +), CAediting_1404101(5142191, +), CAediting_1404102(5142192, +), CAediting_1404103(5142300, +), CAediting_1404104(5142326, +), CAediting_1404105(5142327, +), CAediting_1404106(5142886, +), CAediting_1404107(5142982, +), CAediting_1404108(5143118, +), CAediting_1404109(5144041, +), CAediting_1404110(5151488, +), CAediting_1404111(5152487, +), CAediting_1404112(5154706, +), CAediting_1404113(5168146, +), CAediting_1404114(5168288, +), CAediting_1404115(5168294, +), CAediting_1404116(5168295, +), CAediting_1404117(5168336, +), CAediting_1404118(5168364, +), CAediting_1404119(5168365, +), CAediting_1404120(5179305, +), CAediting_1404121(5189496, +), CAediting_1404122(5189503, +), CAediting_1404123(5189535, +), CAediting_1404124(5194870, +), CAediting_1404125(5194877, +), CAediting_1404126(5194880, +), CAediting_1404127(5194887, +), CAediting_1404128(5194893, +), CAediting_1404129(5194899, +), CAediting_1404130(5194900, +), CAediting_1404131(5194907, +), CAediting_1404132(5194911, +), CAediting_1404133(5195145, +), CAediting_1404134(5195159, +), CAediting_1404135(5195166, +), CAediting_1404136(5195172, +),

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RNA editing positional annotations for CDS2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1404062	chr20_5128524_+	ncRNA_exonic
CAediting_1404063	chr20_5128525_+	ncRNA_exonic
CAediting_1404064	chr20_5128537_+	ncRNA_exonic
CAediting_1404065	chr20_5128551_+	ncRNA_exonic
CAediting_1404066	chr20_5129543_+	ncRNA_intronic
CAediting_1404067	chr20_5129572_+	ncRNA_intronic
CAediting_1404068	chr20_5129622_+	ncRNA_intronic
CAediting_1404069	chr20_5129625_+	ncRNA_intronic
CAediting_1404070	chr20_5129662_+	ncRNA_intronic
CAediting_1404071	chr20_5129670_+	ncRNA_intronic
CAediting_1404072	chr20_5129790_+	ncRNA_intronic
CAediting_1404073	chr20_5130034_+	ncRNA_intronic
CAediting_1404074	chr20_5130689_+	ncRNA_intronic
CAediting_1404075	chr20_5130770_+	ncRNA_intronic
CAediting_1404076	chr20_5130837_+	ncRNA_intronic
CAediting_1404077	chr20_5130872_+	ncRNA_intronic
CAediting_1404078	chr20_5130880_+	ncRNA_intronic
CAediting_1404079	chr20_5130914_+	ncRNA_intronic
CAediting_1404080	chr20_5130999_+	ncRNA_intronic
CAediting_1404081	chr20_5131021_+	ncRNA_intronic
CAediting_1404082	chr20_5132237_+	ncRNA_intronic
CAediting_1404083	chr20_5133050_+	ncRNA_intronic
CAediting_1404084	chr20_5133060_+	ncRNA_intronic
CAediting_1404085	chr20_5133064_+	ncRNA_intronic
CAediting_1404086	chr20_5133095_+	ncRNA_intronic
CAediting_1404087	chr20_5133096_+	ncRNA_intronic
CAediting_1404088	chr20_5133116_+	ncRNA_intronic
CAediting_1404089	chr20_5133120_+	ncRNA_intronic
CAediting_1404090	chr20_5133283_+	ncRNA_intronic
CAediting_1404091	chr20_5133331_+	ncRNA_intronic
CAediting_1404092	chr20_5133394_+	ncRNA_intronic
CAediting_1404093	chr20_5134590_+	ncRNA_intronic
CAediting_1404094	chr20_5134660_+	ncRNA_intronic
CAediting_1404095	chr20_5134718_+	ncRNA_intronic
CAediting_1404096	chr20_5134721_+	ncRNA_intronic
CAediting_1404097	chr20_5137478_+	ncRNA_intronic
CAediting_1404098	chr20_5138493_+	ncRNA_intronic
CAediting_1404099	chr20_5138585_+	ncRNA_intronic
CAediting_1404100	chr20_5138612_+	ncRNA_intronic
CAediting_1404101	chr20_5142191_+	ncRNA_intronic
CAediting_1404102	chr20_5142192_+	ncRNA_intronic
CAediting_1404103	chr20_5142300_+	ncRNA_intronic
CAediting_1404104	chr20_5142326_+	ncRNA_intronic
CAediting_1404105	chr20_5142327_+	ncRNA_intronic
CAediting_1404106	chr20_5142886_+	ncRNA_intronic
CAediting_1404107	chr20_5142982_+	ncRNA_intronic
CAediting_1404108	chr20_5143118_+	ncRNA_intronic
CAediting_1404109	chr20_5144041_+	ncRNA_intronic
CAediting_1404110	chr20_5151488_+	ncRNA_intronic
CAediting_1404111	chr20_5152487_+	ncRNA_intronic
CAediting_1404112	chr20_5154706_+	ncRNA_intronic
CAediting_1404113	chr20_5168146_+	ncRNA_intronic
CAediting_1404114	chr20_5168288_+	ncRNA_intronic
CAediting_1404115	chr20_5168294_+	ncRNA_intronic
CAediting_1404116	chr20_5168295_+	ncRNA_intronic
CAediting_1404117	chr20_5168336_+	ncRNA_intronic
CAediting_1404118	chr20_5168364_+	ncRNA_intronic
CAediting_1404119	chr20_5168365_+	ncRNA_intronic
CAediting_1404120	chr20_5179305_+	ncRNA_intronic
CAediting_1404121	chr20_5189496_+	ncRNA_intronic
CAediting_1404122	chr20_5189503_+	ncRNA_intronic
CAediting_1404123	chr20_5189535_+	ncRNA_intronic
CAediting_1404124	chr20_5194870_+	UTR3
CAediting_1404125	chr20_5194877_+	UTR3
CAediting_1404126	chr20_5194880_+	UTR3
CAediting_1404127	chr20_5194887_+	UTR3
CAediting_1404128	chr20_5194893_+	UTR3
CAediting_1404129	chr20_5194899_+	UTR3
CAediting_1404130	chr20_5194900_+	UTR3
CAediting_1404131	chr20_5194907_+	UTR3
CAediting_1404132	chr20_5194911_+	UTR3
CAediting_1404133	chr20_5195145_+	UTR3
CAediting_1404134	chr20_5195159_+	UTR3
CAediting_1404135	chr20_5195166_+	UTR3
CAediting_1404136	chr20_5195172_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1404062	chr20_5128524_+	SINE	Alu	FLAM_A
CAediting_1404063	chr20_5128525_+	SINE	Alu	FLAM_A
CAediting_1404064	chr20_5128537_+	SINE	Alu	FLAM_A
CAediting_1404065	chr20_5128551_+	SINE	Alu	FLAM_A
CAediting_1404066	chr20_5129543_+	SINE	Alu	AluSp
CAediting_1404067	chr20_5129572_+	SINE	Alu	AluSp
CAediting_1404068	chr20_5129622_+	SINE	Alu	AluSp
CAediting_1404069	chr20_5129625_+	SINE	Alu	AluSp
CAediting_1404070	chr20_5129662_+	SINE	Alu	AluSp
CAediting_1404071	chr20_5129670_+	SINE	Alu	AluSp
CAediting_1404072	chr20_5129790_+	SINE	Alu	AluSx3
CAediting_1404073	chr20_5130034_+	SINE	Alu	AluSq2
CAediting_1404074	chr20_5130689_+	SINE	Alu	AluSp
CAediting_1404075	chr20_5130770_+	SINE	Alu	AluSp
CAediting_1404076	chr20_5130837_+	SINE	Alu	AluY
CAediting_1404077	chr20_5130872_+	SINE	Alu	AluY
CAediting_1404078	chr20_5130880_+	SINE	Alu	AluY
CAediting_1404079	chr20_5130914_+	SINE	Alu	AluY
CAediting_1404080	chr20_5130999_+	SINE	Alu	AluY
CAediting_1404081	chr20_5131021_+	SINE	Alu	AluY
CAediting_1404082	chr20_5132237_+	SINE	Alu	AluSx
CAediting_1404083	chr20_5133050_+	SINE	Alu	AluY
CAediting_1404084	chr20_5133060_+	SINE	Alu	AluY
CAediting_1404085	chr20_5133064_+	SINE	Alu	AluY
CAediting_1404086	chr20_5133095_+	SINE	Alu	AluY
CAediting_1404087	chr20_5133096_+	SINE	Alu	AluY
CAediting_1404088	chr20_5133116_+	SINE	Alu	AluY
CAediting_1404089	chr20_5133120_+	SINE	Alu	AluY
CAediting_1404090	chr20_5133283_+	SINE	Alu	AluJo
CAediting_1404091	chr20_5133331_+	SINE	Alu	AluJo
CAediting_1404092	chr20_5133394_+	SINE	Alu	AluJo
CAediting_1404093	chr20_5134590_+	SINE	Alu	AluSq2
CAediting_1404094	chr20_5134660_+	SINE	Alu	AluSq2
CAediting_1404095	chr20_5134718_+	SINE	Alu	AluSq2
CAediting_1404096	chr20_5134721_+	SINE	Alu	AluSq2
CAediting_1404097	chr20_5137478_+	SINE	Alu	AluSz
CAediting_1404098	chr20_5138493_+	SINE	Alu	AluSq2
CAediting_1404099	chr20_5138585_+	SINE	Alu	AluSq2
CAediting_1404100	chr20_5138612_+	SINE	Alu	AluSq2
CAediting_1404101	chr20_5142191_+	SINE	Alu	AluSz
CAediting_1404102	chr20_5142192_+	SINE	Alu	AluSz
CAediting_1404103	chr20_5142300_+	SINE	Alu	AluSz
CAediting_1404104	chr20_5142326_+	SINE	Alu	AluSz
CAediting_1404105	chr20_5142327_+	SINE	Alu	AluSz
CAediting_1404106	chr20_5142886_+	SINE	Alu	AluJo
CAediting_1404107	chr20_5142982_+	SINE	Alu	AluJo
CAediting_1404108	chr20_5143118_+	SINE	Alu	AluJo
CAediting_1404109	chr20_5144041_+	SINE	Alu	AluSz6
CAediting_1404110	chr20_5151488_+	SINE	Alu	FLAM_A
CAediting_1404111	chr20_5152487_+	SINE	Alu	AluSz
CAediting_1404112	chr20_5154706_+	SINE	Alu	AluJb
CAediting_1404113	chr20_5168146_+	SINE	Alu	AluSx1
CAediting_1404114	chr20_5168288_+	SINE	Alu	AluSx1
CAediting_1404115	chr20_5168294_+	SINE	Alu	AluSx1
CAediting_1404116	chr20_5168295_+	SINE	Alu	AluSx1
CAediting_1404117	chr20_5168336_+	SINE	Alu	AluSx1
CAediting_1404118	chr20_5168364_+	SINE	Alu	AluSx1
CAediting_1404119	chr20_5168365_+	SINE	Alu	AluSx1
CAediting_1404120	chr20_5179305_+	SINE	Alu	AluSx1
CAediting_1404121	chr20_5189496_+	SINE	Alu	AluJr
CAediting_1404122	chr20_5189503_+	SINE	Alu	AluJr
CAediting_1404123	chr20_5189535_+	SINE	Alu	AluJr
CAediting_1404124	chr20_5194870_+	SINE	MIR	MIRb
CAediting_1404125	chr20_5194877_+	SINE	MIR	MIRb
CAediting_1404126	chr20_5194880_+	SINE	MIR	MIRb
CAediting_1404127	chr20_5194887_+	SINE	MIR	MIRb
CAediting_1404128	chr20_5194893_+	SINE	MIR	MIRb
CAediting_1404129	chr20_5194899_+	SINE	MIR	MIRb
CAediting_1404130	chr20_5194900_+	SINE	MIR	MIRb
CAediting_1404131	chr20_5194907_+	SINE	MIR	MIRb
CAediting_1404132	chr20_5194911_+	SINE	MIR	MIRb
CAediting_1404133	chr20_5195145_+	SINE	MIR	MIRb
CAediting_1404134	chr20_5195159_+	SINE	MIR	MIRb
CAediting_1404135	chr20_5195166_+	SINE	MIR	MIRb
CAediting_1404136	chr20_5195172_+	SINE	MIR	MIRb

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RNA A-to-I editing events in the alternative splicing sites for CDS2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000101290.12.CDS2.

Correlation between RNA A-to-I editing and PSI for ENSG00000101290.12.CDS2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CDS2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

TGCT.CAediting_1404125.ENSG00000101290.CDS2.png
Soverview

TGCT.CAediting_1404128.ENSG00000101290.CDS2.png
Soverview

TGCT.CAediting_1404135.ENSG00000101290.CDS2.png
Soverview

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Protein coding region RNA A-to-I editings for CDS2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CDS2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1404128	chr20_5194893_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29a-3p	5194891	5194898	8mer-1a	5194875	5194898	147.00	-17.60
CAediting_1404128	chr20_5194893_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29b-3p	5194891	5194898	8mer-1a	5194876	5194898	145.00	-15.63
CAediting_1404128	chr20_5194893_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29b-3p	5194891	5194898	8mer-1a	5194876	5194898	145.00	-15.63
CAediting_1404128	chr20_5194893_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29c-3p	5194891	5194898	8mer-1a	5194877	5194898	145.00	-15.65
CAediting_1404128	chr20_5194893_+	ENSG00000101290.12	ENST00000460006	hsa-miR-6872-3p	5194887	5194893	7mer-m8	5194874	5194894	146.00	-17.12
CAediting_1404128	chr20_5194893_+	ENSG00000101290.12	ENST00000460006	hsa-miR-767-5p	5194890	5194896	7mer-m8	5194875	5194897	155.00	-21.93
CAediting_1404129	chr20_5194899_+	ENSG00000101290.12	ENST00000460006	hsa-miR-383-3p	5194892	5194899	8mer-1a	5194878	5194899	159.00	-24.93
CAediting_1404130	chr20_5194900_+	ENSG00000101290.12	ENST00000460006	hsa-miR-5195-5p	5194897	5194903	7mer-m8	5194880	5194904	145.00	-22.91
CAediting_1404132	chr20_5194911_+	ENSG00000101290.12	ENST00000460006	hsa-miR-3912-3p	5194908	5194915	8mer-1a	5194895	5194915	140.00	-12.66
CAediting_1404135	chr20_5195166_+	ENSG00000101290.12	ENST00000460006	hsa-miR-105-5p	5195159	5195165	7mer-m8	5195144	5195166	150.00	-13.43
CAediting_1404135	chr20_5195166_+	ENSG00000101290.12	ENST00000460006	hsa-miR-105-5p	5195159	5195165	7mer-m8	5195144	5195166	150.00	-13.43
CAediting_1404135	chr20_5195166_+	ENSG00000101290.12	ENST00000460006	hsa-miR-7853-5p	5195159	5195165	7mer-m8	5195143	5195166	145.00	-12.27
CAediting_1404136	chr20_5195172_+	ENSG00000101290.12	ENST00000460006	hsa-miR-3622a-5p	5195170	5195176	7mer-m8	5195158	5195177	156.00	-26.60
CAediting_1404136	chr20_5195172_+	ENSG00000101290.12	ENST00000460006	hsa-miR-564	5195169	5195175	7mer-m8	5195158	5195176	150.00	-22.06
CAediting_1404124	chr20_5194870_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29a-3p	5194868	5194874	7mer-m8	5194850	5194875	151.00	-18.02
CAediting_1404124	chr20_5194870_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29b-3p	5194868	5194874	7mer-m8	5194849	5194875	156.00	-19.13
CAediting_1404124	chr20_5194870_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29b-3p	5194868	5194874	7mer-m8	5194849	5194875	156.00	-19.13
CAediting_1404124	chr20_5194870_+	ENSG00000101290.12	ENST00000460006	hsa-miR-29c-3p	5194868	5194874	7mer-m8	5194850	5194875	156.00	-16.31

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1404135	chr20_5195166_+	ENSG00000101290.12	ENST00000460006	hsa-miR-190b-3p	5195160	5195166	7mer-m8	5195146	5195167	152	-11.23
CAediting_1404127	chr20_5194887_+	ENSG00000101290.12	ENST00000460006	hsa-miR-221-5p	5194882	5194888	7mer-m8	5194869	5194889	152	-16.37
CAediting_1404127	chr20_5194887_+	ENSG00000101290.12	ENST00000460006	hsa-miR-3116	5194884	5194890	7mer-1a	5194869	5194890	148	-26.68
CAediting_1404127	chr20_5194887_+	ENSG00000101290.12	ENST00000460006	hsa-miR-3116	5194884	5194890	7mer-1a	5194869	5194890	148	-26.68
CAediting_1404136	chr20_5195172_+	ENSG00000101290.12	ENST00000460006	hsa-miR-3622b-5p	5195169	5195175	7mer-m8	5195157	5195176	142	-19.43
CAediting_1404125	chr20_5194877_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4477a	5194873	5194879	7mer-m8	5194854	5194880	154	-10.38
CAediting_1404126	chr20_5194880_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4477a	5194873	5194879	7mer-m8	5194854	5194880	154	-10.38
CAediting_1404125	chr20_5194877_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4477a	5194873	5194879	7mer-m8	5194854	5194880	154	-10.38
CAediting_1404126	chr20_5194880_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4477a	5194873	5194879	7mer-m8	5194854	5194880	154	-10.38
CAediting_1404131	chr20_5194907_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4495	5194903	5194910	8mer-1a	5194887	5194910	146	-13.1
CAediting_1404125	chr20_5194877_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4503	5194871	5194877	7mer-m8	5194859	5194878	145	-6.18
CAediting_1404128	chr20_5194893_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4633-5p	5194886	5194892	7mer-m8	5194874	5194893	155	-17.65
CAediting_1404127	chr20_5194887_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4720-5p	5194882	5194887	6mer	5194865	5194888	141	-20.95
CAediting_1404136	chr20_5195172_+	ENSG00000101290.12	ENST00000460006	hsa-miR-5579-5p	5195166	5195172	7mer-m8	5195153	5195173	145	-14.82
CAediting_1404127	chr20_5194887_+	ENSG00000101290.12	ENST00000460006	hsa-miR-5588-5p	5194882	5194887	6mer	5194866	5194888	140	-15.71
CAediting_1404127	chr20_5194887_+	ENSG00000101290.12	ENST00000460006	hsa-miR-8073	5194882	5194888	7mer-m8	5194867	5194889	146	-20.61

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000101290.12	ENST00000460006	hsa-miR-605-3p	5192665	5192671	7mer-m8	5192653	5192672	148	-18.87
CAediting_748296	chr10_51299626_+	ENSG00000101290.12	ENST00000460006	hsa-miR-605-3p	5193175	5193181	7mer-m8	5193161	5193182	155	-20.04
CAediting_980496	chr14_31014685_-	ENSG00000101290.12	ENST00000460006	hsa-miR-624-3p	5194742	5194748	7mer-m8	5194729	5194749	148	-13.69
CAediting_688081	chr9_63819627_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4477b	5191426	5191432	7mer-m8	5191412	5191433	140	-10.13
CAediting_1054808	chr15_66496985_-	ENSG00000101290.12	ENST00000460006	hsa-miR-4512	5191826	5191832	7mer-m8	5191809	5191833	142	-17.13
CAediting_1229414	chr17_67471546_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5190676	5190682	7mer-m8	5190659	5190683	143	-12.71
CAediting_1229415	chr17_67471547_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5196623	5196629	7mer-m8	5196607	5196630	145	-14.82
CAediting_1351755	chr19_40282625_-	ENSG00000101290.12	ENST00000460006	hsa-miR-641	5190982	5190988	7mer-m8	5190965	5190989	155	-16.18
CAediting_1368054	chr19_46709310_-	ENSG00000101290.12	ENST00000460006	hsa-miR-320e	5195455	5195462	8mer-1a	5195445	5195462	151	-20.8
CAediting_228905	chr2_188297554_+	ENSG00000101290.12	ENST00000460006	hsa-miR-561-3p	5194108	5194114	7mer-m8	5194096	5194115	144	-16.31
CAediting_442554	chr5_154685830_+	ENSG00000101290.12	ENST00000460006	hsa-miR-1303	5190282	5190288	7mer-m8	5190268	5190289	168	-31.02
CAediting_580943	chr7_100356700_+	ENSG00000101290.12	ENST00000460006	hsa-miR-6840-3p	5196429	5196435	7mer-m8	5196414	5196436	151	-27.34
CAediting_604450	chr7_133034877_-	ENSG00000101290.12	ENST00000460006	hsa-miR-3654	5191683	5191690	8mer-1a	5191671	5191690	156	-23.74
CAediting_468389	chr6_31355314_-	ENSG00000101290.12	ENST00000460006	hsa-miR-6891-5p	5195463	5195469	7mer-m8	5195451	5195470	149	-21.96

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_573001	chr7_92204086_-	ENSG00000101290.12	ENST00000460006	hsa-miR-1285-5p	5191441	5191447	7mer-m8	5191428	5191448	143	-15.59
CAediting_393	chr1_1167164_+	ENSG00000101290.12	ENST00000460006	hsa-miR-200b-3p	5191870	5191876	7mer-m8	5191856	5191877	140	-10.47
CAediting_393	chr1_1167164_+	ENSG00000101290.12	ENST00000460006	hsa-miR-200b-3p	5193284	5193290	7mer-m8	5193269	5193291	149	-14.92
CAediting_1368054	chr19_46709310_-	ENSG00000101290.12	ENST00000460006	hsa-miR-320e	5194216	5194222	7mer-m8	5194206	5194223	148	-15.51
CAediting_604450	chr7_133034877_-	ENSG00000101290.12	ENST00000460006	hsa-miR-3654	5194707	5194713	7mer-m8	5194696	5194714	151	-14.4
CAediting_688081	chr9_63819627_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4477b	5192047	5192053	7mer-m8	5192033	5192054	148	-9.07
CAediting_688080	chr9_63819626_+	ENSG00000101290.12	ENST00000460006	hsa-miR-4477b	5192047	5192053	7mer-m8	5192033	5192054	148	-9.07
CAediting_1054808	chr15_66496985_-	ENSG00000101290.12	ENST00000460006	hsa-miR-4512	5192030	5192036	7mer-m8	5192016	5192037	148	-17.49
CAediting_1524209	chrX_134546392_-	ENSG00000101290.12	ENST00000460006	hsa-miR-503-5p	5194441	5194446	6mer	5194425	5194447	140	-23.85
CAediting_1524209	chrX_134546392_-	ENSG00000101290.12	ENST00000460006	hsa-miR-503-5p	5191052	5191057	6mer	5191039	5191061	141	-27.46
CAediting_1524209	chrX_134546392_-	ENSG00000101290.12	ENST00000460006	hsa-miR-503-5p	5191055	5191060	6mer	5191039	5191061	141	-27.46
CAediting_1229413	chr17_67471544_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5192708	5192715	8mer-1a	5192691	5192715	140	-7.58
CAediting_1229414	chr17_67471546_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5192708	5192715	8mer-1a	5192691	5192715	140	-7.58
CAediting_1229415	chr17_67471547_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5192708	5192715	8mer-1a	5192691	5192715	140	-7.58
CAediting_1229413	chr17_67471544_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5197230	5197236	7mer-m8	5197215	5197237	151	-12.46
CAediting_1229414	chr17_67471546_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5197230	5197236	7mer-m8	5197215	5197237	151	-12.46
CAediting_1229415	chr17_67471547_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5197230	5197236	7mer-m8	5197215	5197237	151	-12.46
CAediting_1229413	chr17_67471544_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5197248	5197254	7mer-m8	5197231	5197255	147	-8.32
CAediting_1229414	chr17_67471546_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5197248	5197254	7mer-m8	5197231	5197255	147	-8.32
CAediting_1229415	chr17_67471547_+	ENSG00000101290.12	ENST00000460006	hsa-miR-548aa	5197248	5197254	7mer-m8	5197231	5197255	147	-8.32
CAediting_748296	chr10_51299626_+	ENSG00000101290.12	ENST00000460006	hsa-miR-605-3p	5190717	5190723	7mer-m8	5190698	5190724	141	-16.69
CAediting_980496	chr14_31014685_-	ENSG00000101290.12	ENST00000460006	hsa-miR-624-3p	5192505	5192511	7mer-m8	5192492	5192512	149	-16.06
CAediting_980496	chr14_31014685_-	ENSG00000101290.12	ENST00000460006	hsa-miR-624-3p	5193512	5193518	7mer-m8	5193499	5193519	153	-17.75
CAediting_580943	chr7_100356700_+	ENSG00000101290.12	ENST00000460006	hsa-miR-6840-3p	5191998	5192004	7mer-m8	5191984	5192005	154	-26.42
CAediting_580943	chr7_100356700_+	ENSG00000101290.12	ENST00000460006	hsa-miR-6840-3p	5195117	5195123	7mer-m8	5195103	5195124	140	-17.74
CAediting_580943	chr7_100356700_+	ENSG00000101290.12	ENST00000460006	hsa-miR-6840-3p	5196081	5196087	7mer-m8	5196067	5196088	148	-20.95

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CDS2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for CDS2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_1404125	chr20_5194877_+	1.49305086762254e-14	0.503124204584586	.	.	.	.
BRCA	CAediting_1404125	chr20_5194877_+	2.63471301529892e-16	0.36738246771307	.	.	.	.
LIHC	CAediting_1404125	chr20_5194877_+	0.000841844664066198	0.441112202566454	.	.	.	.
LUAD	CAediting_1404125	chr20_5194877_+	9.39928823081742e-05	0.319670343525848	.	.	.	.
LUSC	CAediting_1404125	chr20_5194877_+	0.00574309574698652	0.261738285146645	.	.	.	.
GBM	CAediting_1404125	chr20_5194877_+	0.0343269138861759	0.269253457231221	.	.	.	.
STAD	CAediting_1404125	chr20_5194877_+	0.0498402755597132	0.18176333358251	.	.	.	.
THCA	CAediting_1404125	chr20_5194877_+	0.000530070235131572	0.258576504102389	.	.	.	.
KIRC	CAediting_1404125	chr20_5194877_+	0.0039749358233954	0.151030104677288	.	.	.	.
OV	CAediting_1404125	chr20_5194877_+	0.0213654752165524	0.226577413961658	.	.	.	.
PCPG	CAediting_1404125	chr20_5194877_+	0.000199747001748913	0.356934999861499	.	.	.	.
SKCM	CAediting_1404125	chr20_5194877_+	1.05910103365811e-10	0.445521695134474	.	.	.	.
SARC	CAediting_1404125	chr20_5194877_+	0.000413338063541267	0.452208010687431	.	.	.	.
TGCT	CAediting_1404125	chr20_5194877_+	1.07794469404989e-05	0.546820923694664	.	.	.	.
BLCA	CAediting_1404128	chr20_5194893_+	0.00200329339142255	0.336368020106785	0.0117111912844173	0.277146742289026	.	.
LGG	CAediting_1404128	chr20_5194893_+	7.67118509455278e-18	0.369444659473982	.	.	.	.
BRCA	CAediting_1404128	chr20_5194893_+	9.18885793964065e-51	0.516851649093785	.	.	.	.
LIHC	CAediting_1404128	chr20_5194893_+	0.000119609905463852	0.42187180143962	.	.	.	.
CESC	CAediting_1404128	chr20_5194893_+	2.39020257658524e-06	0.466866413629962	.	.	.	.
LUAD	CAediting_1404128	chr20_5194893_+	2.88885190511971e-09	0.35901650811999	.	.	.	.
COAD	CAediting_1404128	chr20_5194893_+	0.000449694032592184	0.334903228712989	.	.	.	.
LUSC	CAediting_1404128	chr20_5194893_+	1.65205668949995e-13	0.438614924184027	.	.	.	.
GBM	CAediting_1404128	chr20_5194893_+	7.71140848792169e-06	0.361926094838803	.	.	.	.
PRAD	CAediting_1404128	chr20_5194893_+	1.81547923816393e-08	0.298492910289904	.	.	.	.
HNSC	CAediting_1404128	chr20_5194893_+	2.01886621966094e-10	0.424557304276582	0.012961157452171	0.172873102994426	.	.
STAD	CAediting_1404128	chr20_5194893_+	0.0067004976746304	0.16939627320896	.	.	.	.
THCA	CAediting_1404128	chr20_5194893_+	1.59845227139765e-10	0.310490502999759	.	.	.	.
KIRC	CAediting_1404128	chr20_5194893_+	2.05320429040132e-10	0.288669111885607	.	.	.	.
KIRP	CAediting_1404128	chr20_5194893_+	0.000494081438889595	0.236707330955022	.	.	.	.
ESCA	CAediting_1404128	chr20_5194893_+	0.00342592042423021	0.239100158020011	0.0162694912602003	0.197238116497576	.	.
LAML	CAediting_1404128	chr20_5194893_+	2.71215272031493e-05	0.364529415542946	.	.	.	.
OV	CAediting_1404128	chr20_5194893_+	2.58002770838133e-08	0.388463566993898	.	.	.	.
PAAD	CAediting_1404128	chr20_5194893_+	0.0104281289801831	0.276468002252284	.	.	.	.
PCPG	CAediting_1404128	chr20_5194893_+	1.36815923084433e-12	0.525372276424119	.	.	.	.
SKCM	CAediting_1404128	chr20_5194893_+	2.70486919069489e-32	0.544789867428037	.	.	.	.
UVM	CAediting_1404128	chr20_5194893_+	0.00247638250481763	0.349006130641893	.	.	.	.
READ	CAediting_1404128	chr20_5194893_+	0.000256735184302319	0.47007215299433	.	.	.	.
SARC	CAediting_1404128	chr20_5194893_+	1.77696838501442e-08	0.458366377644001	.	.	.	.
TGCT	CAediting_1404128	chr20_5194893_+	1.32296793187087e-09	0.637479844670936	.	.	.	.
THYM	CAediting_1404128	chr20_5194893_+	.	.	0.0169333967673437	0.31519223133152	0.00795039445519683	0.348191964039874
LGG	CAediting_1404130	chr20_5194900_+	0.000394820443493651	0.442878610069915	.	.	.	.
BRCA	CAediting_1404130	chr20_5194900_+	0.000737281469404734	0.229528750265332	.	.	.	.
SKCM	CAediting_1404130	chr20_5194900_+	0.0106530983625932	0.244843434157362	.	.	.	.
BLCA	CAediting_1404134	chr20_5195159_+	0.0421101365944933	0.230737353158459	.	.	.	.
LGG	CAediting_1404134	chr20_5195159_+	2.90541618802279e-28	0.525845140849557	.	.	.	.
BRCA	CAediting_1404134	chr20_5195159_+	4.06800342325731e-40	0.49155417143664	.	.	.	.
LIHC	CAediting_1404134	chr20_5195159_+	6.88215705991226e-06	0.417663058492398	.	.	.	.
CESC	CAediting_1404134	chr20_5195159_+	0.00278221278459198	0.303594470524605	.	.	.	.
LUAD	CAediting_1404134	chr20_5195159_+	0.000936055038668426	0.218659044400563	.	.	.	.
LUSC	CAediting_1404134	chr20_5195159_+	0.000468804264250185	0.244497741131961	.	.	0.00526873704476472	0.196108827876509
GBM	CAediting_1404134	chr20_5195159_+	0.000187355430823104	0.372325465922357	.	.	.	.
HNSC	CAediting_1404134	chr20_5195159_+	0.000588378801144531	0.249686637998529	.	.	.	.
STAD	CAediting_1404134	chr20_5195159_+	0.0228930656624759	0.160043447707352	.	.	.	.
THCA	CAediting_1404134	chr20_5195159_+	3.09701249830753e-05	0.238844042750727	.	.	.	.
KIRC	CAediting_1404134	chr20_5195159_+	8.566671880899e-10	0.293566072024943	.	.	.	.
PCPG	CAediting_1404134	chr20_5195159_+	1.50588978113988e-07	0.414247661549287	.	.	.	.
SKCM	CAediting_1404134	chr20_5195159_+	2.81985308901086e-11	0.373696229863555	.	.	.	.
UVM	CAediting_1404134	chr20_5195159_+	0.00788522941921008	0.368013826792383	.	.	.	.
SARC	CAediting_1404134	chr20_5195159_+	0.00110276818344221	0.314088064848413	.	.	.	.
TGCT	CAediting_1404134	chr20_5195159_+	2.39781902257661e-05	0.481933733815864	.	.	.	.
BLCA	CAediting_1404135	chr20_5195166_+	.	.	.	.	0.0230863881443411	0.308806821686157
LGG	CAediting_1404135	chr20_5195166_+	8.55239990350595e-18	0.637528472205121	.	.	.	.
BRCA	CAediting_1404135	chr20_5195166_+	8.43446642734048e-30	0.490336825604208	.	.	.	.
LIHC	CAediting_1404135	chr20_5195166_+	6.81309990785206e-05	0.411475613024671	.	.	.	.
LUAD	CAediting_1404135	chr20_5195166_+	0.000826906865547534	0.247742539936733	.	.	.	.
LUSC	CAediting_1404135	chr20_5195166_+	.	.	0.0388139216398978	0.192127215855485	0.0080310542869743	0.245007291697648
GBM	CAediting_1404135	chr20_5195166_+	0.00450309880277364	0.384245479600569	.	.	.	.
PRAD	CAediting_1404135	chr20_5195166_+	0.00337666280932671	0.277147598702362	.	.	.	.
HNSC	CAediting_1404135	chr20_5195166_+	.	.	0.0413496927325571	0.183497778646726	.	.
KIRC	CAediting_1404135	chr20_5195166_+	0.0487254660774867	0.111863794728992	.	.	.	.
PCPG	CAediting_1404135	chr20_5195166_+	8.76534483479837e-07	0.475131515998096	.	.	.	.
SKCM	CAediting_1404135	chr20_5195166_+	1.22358248719158e-10	0.433017311531964	.	.	.	.
SARC	CAediting_1404135	chr20_5195166_+	0.000413365633218631	0.422235491629936	.	.	.	.
TGCT	CAediting_1404135	chr20_5195166_+	1.78725182382886e-10	0.6877071771194	.	.	.	.

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Relation with cancer stages for CDS2

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_1404128	chr20_5194893_+	0.0289789778436764	0.242772248390442
BRCA	pathologic_stage	CAediting_1404132	chr20_5194911_+	0.0159758107801811	0.289123495648776
COAD	pathologic_stage	CAediting_1404134	chr20_5195159_+	0.0386893510120711	-0.220822438846995
KIRC	pathologic_stage	CAediting_1404128	chr20_5194893_+	0.0342580344817993	0.0982014256392802
KIRC	pathologic_stage	CAediting_1404132	chr20_5194911_+	0.00489035817652599	0.358679005056578
KIRP	clinical_stage	CAediting_1404125	chr20_5194877_+	0.00933626103629025	0.317708634013206
KIRP	clinical_stage	CAediting_1404128	chr20_5194893_+	0.00895545360203378	0.220943753735595
KIRP	clinical_stage	CAediting_1404134	chr20_5195159_+	0.0330461919959371	0.205304535726104
KIRP	pathologic_stage	CAediting_1404125	chr20_5194877_+	0.0422911356903687	0.207706484426169
KIRP	pathologic_stage	CAediting_1404128	chr20_5194893_+	0.00117706386885855	0.233044106958599
KIRP	pathologic_stage	CAediting_1404134	chr20_5195159_+	0.0167383272286556	0.197737473420834
LUAD	pathologic_stage	CAediting_1404128	chr20_5194893_+	0.0390750809761038	0.130075649884431
LUSC	pathologic_stage	CAediting_1404134	chr20_5195159_+	0.0194637984693928	0.164705972106992
STAD	pathologic_stage	CAediting_1404128	chr20_5194893_+	0.0154439269980004	0.156181288279616
THCA	pathologic_stage	CAediting_1404128	chr20_5194893_+	0.0460240946575639	0.0998217193830805

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Relation with survival for CDS2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
BRCA	CAediting_1404132	chr20_5194911_+	0.0281057330065387	0.0169229	4.14774e-11
OV	CAediting_1404130	chr20_5194900_+	0.0129595941077747	0.0202316	609.748

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RelatedDrugs for CDS2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CDS2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene