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Editing gene: TMEM87B (CAeditome ID:84910)

Gene summary for TMEM87B

Gene summary

Gene information	Gene symbol	TMEM87B
	Gene ID	84910
	Gene name	transmembrane protein 87B
	Synonyms	-
	Cytomap	2q13
	Type of gene	protein-coding
	Description	transmembrane protein 87B
	Modification date	20210518
	UniProtAcc	Q96K49
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for TMEM87B

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000153214.8

RNA A-to-I editing events in Cancer.

CAediting_207244(112060119, +), CAediting_207245(112060576, +), CAediting_207246(112060717, +), CAediting_207247(112060784, +), CAediting_207248(112060789, +), CAediting_207249(112065579, +), CAediting_207250(112065580, +), CAediting_207251(112065586, +), CAediting_207252(112065587, +), CAediting_207253(112065602, +), CAediting_207254(112065605, +), CAediting_207255(112067438, +), CAediting_207256(112067448, +), CAediting_207257(112067449, +), CAediting_207258(112067452, +), CAediting_207259(112067478, +), CAediting_207260(112075280, +), CAediting_207261(112076132, +), CAediting_207262(112076133, +), CAediting_207263(112076142, +), CAediting_207264(112076172, +), CAediting_207265(112076173, +), CAediting_207266(112076177, +), CAediting_207267(112076414, +), CAediting_207268(112076433, +), CAediting_207269(112076434, +), CAediting_207270(112076439, +), CAediting_207271(112076440, +), CAediting_207272(112076469, +), CAediting_207273(112076479, +), CAediting_207274(112076489, +), CAediting_207275(112076497, +), CAediting_207276(112076529, +), CAediting_207277(112076540, +), CAediting_207278(112076575, +), CAediting_207279(112076587, +), CAediting_207280(112076602, +), CAediting_207281(112076608, +), CAediting_207282(112076938, +), CAediting_207283(112076946, +), CAediting_207284(112076947, +), CAediting_207285(112076952, +), CAediting_207286(112076955, +), CAediting_207287(112076968, +), CAediting_207288(112076970, +), CAediting_207289(112076973, +), CAediting_207290(112076994, +), CAediting_207291(112090434, +), CAediting_207292(112091111, +), CAediting_207293(112091119, +), CAediting_207294(112091120, +), CAediting_207295(112091160, +), CAediting_207296(112091168, +), CAediting_207297(112097592, +), CAediting_207298(112097638, +), CAediting_207299(112097654, +), CAediting_207300(112097658, +), CAediting_207301(112097663, +), CAediting_207302(112098007, +), CAediting_207303(112098045, +), CAediting_207304(112098050, +),

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RNA editing positional annotations for TMEM87B using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_207244	chr2_112060119_+	intronic
CAediting_207245	chr2_112060576_+	intronic
CAediting_207246	chr2_112060717_+	intronic
CAediting_207247	chr2_112060784_+	intronic
CAediting_207248	chr2_112060789_+	intronic
CAediting_207249	chr2_112065579_+	intronic
CAediting_207250	chr2_112065580_+	intronic
CAediting_207251	chr2_112065586_+	intronic
CAediting_207252	chr2_112065587_+	intronic
CAediting_207253	chr2_112065602_+	intronic
CAediting_207254	chr2_112065605_+	intronic
CAediting_207255	chr2_112067438_+	intronic
CAediting_207256	chr2_112067448_+	intronic
CAediting_207257	chr2_112067449_+	intronic
CAediting_207258	chr2_112067452_+	intronic
CAediting_207259	chr2_112067478_+	intronic
CAediting_207260	chr2_112075280_+	intronic
CAediting_207261	chr2_112076132_+	intronic
CAediting_207262	chr2_112076133_+	intronic
CAediting_207263	chr2_112076142_+	intronic
CAediting_207264	chr2_112076172_+	intronic
CAediting_207265	chr2_112076173_+	intronic
CAediting_207266	chr2_112076177_+	intronic
CAediting_207267	chr2_112076414_+	intronic
CAediting_207268	chr2_112076433_+	intronic
CAediting_207269	chr2_112076434_+	intronic
CAediting_207270	chr2_112076439_+	intronic
CAediting_207271	chr2_112076440_+	intronic
CAediting_207272	chr2_112076469_+	intronic
CAediting_207273	chr2_112076479_+	intronic
CAediting_207274	chr2_112076489_+	intronic
CAediting_207275	chr2_112076497_+	intronic
CAediting_207276	chr2_112076529_+	intronic
CAediting_207277	chr2_112076540_+	intronic
CAediting_207278	chr2_112076575_+	intronic
CAediting_207279	chr2_112076587_+	intronic
CAediting_207280	chr2_112076602_+	intronic
CAediting_207281	chr2_112076608_+	intronic
CAediting_207282	chr2_112076938_+	intronic
CAediting_207283	chr2_112076946_+	intronic
CAediting_207284	chr2_112076947_+	intronic
CAediting_207285	chr2_112076952_+	intronic
CAediting_207286	chr2_112076955_+	intronic
CAediting_207287	chr2_112076968_+	intronic
CAediting_207288	chr2_112076970_+	intronic
CAediting_207289	chr2_112076973_+	intronic
CAediting_207290	chr2_112076994_+	intronic
CAediting_207291	chr2_112090434_+	ncRNA_intronic
CAediting_207292	chr2_112091111_+	ncRNA_intronic
CAediting_207293	chr2_112091119_+	ncRNA_intronic
CAediting_207294	chr2_112091120_+	ncRNA_intronic
CAediting_207295	chr2_112091160_+	ncRNA_intronic
CAediting_207296	chr2_112091168_+	ncRNA_intronic
CAediting_207297	chr2_112097592_+	ncRNA_intronic
CAediting_207298	chr2_112097638_+	ncRNA_intronic
CAediting_207299	chr2_112097654_+	ncRNA_intronic
CAediting_207300	chr2_112097658_+	ncRNA_intronic
CAediting_207301	chr2_112097663_+	ncRNA_intronic
CAediting_207302	chr2_112098007_+	ncRNA_intronic
CAediting_207303	chr2_112098045_+	ncRNA_intronic
CAediting_207304	chr2_112098050_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_207244	chr2_112060119_+	SINE	Alu	AluSx3
CAediting_207245	chr2_112060576_+	SINE	Alu	AluSx
CAediting_207246	chr2_112060717_+	SINE	Alu	AluSx
CAediting_207247	chr2_112060784_+	SINE	Alu	AluSx
CAediting_207248	chr2_112060789_+	SINE	Alu	AluSx
CAediting_207249	chr2_112065579_+	SINE	Alu	AluJo
CAediting_207250	chr2_112065580_+	SINE	Alu	AluJo
CAediting_207251	chr2_112065586_+	SINE	Alu	AluJo
CAediting_207252	chr2_112065587_+	SINE	Alu	AluJo
CAediting_207253	chr2_112065602_+	SINE	Alu	AluJo
CAediting_207254	chr2_112065605_+	SINE	Alu	AluJo
CAediting_207255	chr2_112067438_+	SINE	Alu	AluSx
CAediting_207256	chr2_112067448_+	SINE	Alu	AluSx
CAediting_207257	chr2_112067449_+	SINE	Alu	AluSx
CAediting_207258	chr2_112067452_+	SINE	Alu	AluSx
CAediting_207259	chr2_112067478_+	SINE	Alu	AluSx
CAediting_207260	chr2_112075280_+	SINE	Alu	AluSz6
CAediting_207261	chr2_112076132_+	SINE	Alu	AluSx1
CAediting_207262	chr2_112076133_+	SINE	Alu	AluSx1
CAediting_207263	chr2_112076142_+	SINE	Alu	AluSx1
CAediting_207264	chr2_112076172_+	SINE	Alu	AluSx1
CAediting_207265	chr2_112076173_+	SINE	Alu	AluSx1
CAediting_207266	chr2_112076177_+	SINE	Alu	AluSx1
CAediting_207267	chr2_112076414_+	SINE	Alu	AluSx1
CAediting_207268	chr2_112076433_+	SINE	Alu	AluSx1
CAediting_207269	chr2_112076434_+	SINE	Alu	AluSx1
CAediting_207270	chr2_112076439_+	SINE	Alu	AluSx1
CAediting_207271	chr2_112076440_+	SINE	Alu	AluSx1
CAediting_207272	chr2_112076469_+	SINE	Alu	AluSx1
CAediting_207273	chr2_112076479_+	SINE	Alu	AluSx1
CAediting_207274	chr2_112076489_+	SINE	Alu	AluSx1
CAediting_207275	chr2_112076497_+	SINE	Alu	AluSx1
CAediting_207276	chr2_112076529_+	SINE	Alu	AluSx1
CAediting_207277	chr2_112076540_+	SINE	Alu	AluSx1
CAediting_207278	chr2_112076575_+	SINE	Alu	AluSx1
CAediting_207279	chr2_112076587_+	SINE	Alu	AluSx1
CAediting_207280	chr2_112076602_+	SINE	Alu	AluSx1
CAediting_207281	chr2_112076608_+	SINE	Alu	AluSx1
CAediting_207282	chr2_112076938_+	SINE	Alu	FLAM_C
CAediting_207283	chr2_112076946_+	SINE	Alu	FLAM_C
CAediting_207284	chr2_112076947_+	SINE	Alu	FLAM_C
CAediting_207285	chr2_112076952_+	SINE	Alu	FLAM_C
CAediting_207286	chr2_112076955_+	SINE	Alu	FLAM_C
CAediting_207287	chr2_112076968_+	SINE	Alu	FLAM_C
CAediting_207288	chr2_112076970_+	SINE	Alu	FLAM_C
CAediting_207289	chr2_112076973_+	SINE	Alu	FLAM_C
CAediting_207290	chr2_112076994_+	SINE	Alu	FLAM_C
CAediting_207291	chr2_112090434_+	SINE	Alu	AluJr
CAediting_207292	chr2_112091111_+	SINE	Alu	AluSp
CAediting_207293	chr2_112091119_+	SINE	Alu	AluSp
CAediting_207294	chr2_112091120_+	SINE	Alu	AluSp
CAediting_207295	chr2_112091160_+	SINE	Alu	AluSp
CAediting_207296	chr2_112091168_+	SINE	Alu	AluSp
CAediting_207297	chr2_112097592_+	SINE	Alu	AluY
CAediting_207298	chr2_112097638_+	SINE	Alu	AluY
CAediting_207299	chr2_112097654_+	SINE	Alu	AluY
CAediting_207300	chr2_112097658_+	SINE	Alu	AluY
CAediting_207301	chr2_112097663_+	SINE	Alu	AluY
CAediting_207302	chr2_112098007_+	SINE	Alu	AluSg7
CAediting_207303	chr2_112098045_+	SINE	Alu	AluSg7
CAediting_207304	chr2_112098050_+	SINE	Alu	AluSg7

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RNA A-to-I editing events in the alternative splicing sites for TMEM87B

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000153214.8.TMEM87B.

Correlation between RNA A-to-I editing and PSI for ENSG00000153214.8.TMEM87B.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TMEM87B

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for TMEM87B

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for TMEM87B

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TMEM87B

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for TMEM87B

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for TMEM87B

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for TMEM87B

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for TMEM87B

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for TMEM87B

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene