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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: LTBP4 (CAeditome ID:8425)

Gene summary for LTBP4

check button Gene summary
Gene informationGene symbol

LTBP4

Gene ID

8425

Gene namelatent transforming growth factor beta binding protein 4
SynonymsARCL1C|LTBP-4|LTBP4L|LTBP4S
Cytomap

19q13.2

Type of geneprotein-coding
Descriptionlatent-transforming growth factor beta-binding protein 4latent transforming growth factor-beta binding protein 4L
Modification date20210524
UniProtAcc

Q8N2S1

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
LTBP4

GO:0050431

Latent-transforming growth factor beta-binding protein 4

9660815

LTBP4

GO:0030162

Latent-transforming growth factor beta-binding protein 4

9660815

LTBP4

GO:0031012

Latent-transforming growth factor beta-binding protein 4

9660815

LTBP4

GO:0062023

Latent-transforming growth factor beta-binding protein 4

16157329


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RNA A-to-I events for LTBP4

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000090006.16

check button RNA A-to-I editing events in Cancer.
CAediting_1353041(40606881, +), CAediting_1353042(40606951, +), CAediting_1353043(40606971, +), CAediting_1353044(40607012, +), CAediting_1353045(40607025, +), CAediting_1353046(40607033, +), CAediting_1353047(40608649, +), CAediting_1353048(40608657, +), CAediting_1353049(40608658, +), CAediting_1353050(40608663, +), CAediting_1353051(40608704, +), CAediting_1353052(40608710, +), CAediting_1353053(40608724, +), CAediting_1353054(40608725, +), CAediting_1353055(40608727, +), CAediting_1353056(40608733, +), CAediting_1353057(40608734, +), CAediting_1353058(40608735, +), CAediting_1353059(40608746, +), CAediting_1353060(40608755, +), CAediting_1353061(40608761, +), CAediting_1353062(40608790, +), CAediting_1353063(40608791, +), CAediting_1353064(40608796, +), CAediting_1353065(40608823, +), CAediting_1353066(40608826, +), CAediting_1353067(40608836, +), CAediting_1353068(40608839, +), CAediting_1353069(40608843, +), CAediting_1353070(40608852, +), CAediting_1353071(40608856, +), CAediting_1353072(40608861, +), CAediting_1353073(40608863, +), CAediting_1353074(40609756, +), CAediting_1353075(40615651, +), CAediting_1353076(40616586, +), CAediting_1353077(40616612, +), CAediting_1353078(40616627, +), CAediting_1353079(40616630, +), CAediting_1353080(40617523, +), CAediting_1353081(40617541, +), CAediting_1353082(40617553, +), CAediting_1353083(40617565, +), CAediting_1353084(40617569, +), CAediting_1353085(40617570, +), CAediting_1353086(40617589, +), CAediting_1353087(40617594, +), CAediting_1353088(40618334, +), CAediting_1353089(40618340, +), CAediting_1353090(40618360, +), CAediting_1353091(40618377, +), CAediting_1353092(40618538, +), CAediting_1353093(40620259, +), CAediting_1353094(40620260, +), CAediting_1353095(40620264, +), CAediting_1353096(40620325, +), CAediting_1353097(40620338, +), CAediting_1353098(40620339, +), CAediting_1353099(40620342, +), CAediting_1353100(40620350, +), CAediting_1353101(40620356, +), CAediting_1353102(40620369, +), CAediting_1353103(40620394, +), CAediting_1353104(40620561, +), CAediting_1353105(40620566, +), CAediting_1353106(40620577, +), CAediting_1353107(40620597, +), CAediting_1353108(40620598, +), CAediting_1353109(40620599, +), CAediting_1353110(40620600, +), CAediting_1353111(40620611, +), CAediting_1353112(40620614, +), CAediting_1353113(40620615, +), CAediting_1353114(40620616, +), CAediting_1353115(40620617, +), CAediting_1353116(40620618, +), CAediting_1353117(40620620, +), CAediting_1353118(40620623, +), CAediting_1353119(40620625, +), CAediting_1353120(40620626, +), CAediting_1353121(40620629, +), CAediting_1353122(40620639, +), CAediting_1353123(40620655, +), CAediting_1353124(40620656, +), CAediting_1353125(40620671, +), CAediting_1353126(40620672, +), CAediting_1353127(40620678, +), CAediting_1353128(40620682, +), CAediting_1353129(40620686, +), CAediting_1353130(40620687, +), CAediting_1353131(40620688, +), CAediting_1353132(40620696, +), CAediting_1353133(40620701, +), CAediting_1353134(40620725, +), CAediting_1353135(40620738, +), CAediting_1353136(40620752, +), CAediting_1353137(40620755, +), CAediting_1353138(40620990, +), CAediting_1353139(40621081, +), CAediting_1353140(40621117, +), CAediting_1353141(40621123, +), CAediting_1353142(40621140, +), CAediting_1353143(40621145, +), CAediting_1353144(40621164, +), CAediting_1353145(40621177, +), CAediting_1353146(40621772, +), CAediting_1353147(40621829, +), CAediting_1353148(40621847, +), CAediting_1353149(40621887, +), CAediting_1353150(40621984, +), CAediting_1353151(40622011, +), CAediting_1353152(40623249, +), CAediting_1353153(40623375, +), CAediting_1353154(40623386, +), CAediting_1353155(40623404, +), CAediting_1353156(40623455, +), CAediting_1353157(40623458, +), CAediting_1353158(40628446, +), CAediting_1353159(40628463, +), CAediting_1353160(40628873, +),

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RNA editing positional annotations for LTBP4 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1353041chr19_40606881_+ncRNA_intronic
CAediting_1353042chr19_40606951_+ncRNA_intronic
CAediting_1353043chr19_40606971_+ncRNA_intronic
CAediting_1353044chr19_40607012_+ncRNA_intronic
CAediting_1353045chr19_40607025_+ncRNA_intronic
CAediting_1353046chr19_40607033_+ncRNA_intronic
CAediting_1353047chr19_40608649_+ncRNA_exonic
CAediting_1353048chr19_40608657_+ncRNA_exonic
CAediting_1353049chr19_40608658_+ncRNA_exonic
CAediting_1353050chr19_40608663_+ncRNA_exonic
CAediting_1353051chr19_40608704_+ncRNA_exonic
CAediting_1353052chr19_40608710_+ncRNA_exonic
CAediting_1353053chr19_40608724_+ncRNA_exonic
CAediting_1353054chr19_40608725_+ncRNA_exonic
CAediting_1353055chr19_40608727_+ncRNA_exonic
CAediting_1353056chr19_40608733_+ncRNA_exonic
CAediting_1353057chr19_40608734_+ncRNA_exonic
CAediting_1353058chr19_40608735_+ncRNA_exonic
CAediting_1353059chr19_40608746_+ncRNA_exonic
CAediting_1353060chr19_40608755_+ncRNA_exonic
CAediting_1353061chr19_40608761_+ncRNA_exonic
CAediting_1353062chr19_40608790_+ncRNA_exonic
CAediting_1353063chr19_40608791_+ncRNA_exonic
CAediting_1353064chr19_40608796_+ncRNA_exonic
CAediting_1353065chr19_40608823_+ncRNA_exonic
CAediting_1353066chr19_40608826_+ncRNA_exonic
CAediting_1353067chr19_40608836_+ncRNA_exonic
CAediting_1353068chr19_40608839_+ncRNA_exonic
CAediting_1353069chr19_40608843_+ncRNA_exonic
CAediting_1353070chr19_40608852_+ncRNA_exonic
CAediting_1353071chr19_40608856_+ncRNA_exonic
CAediting_1353072chr19_40608861_+ncRNA_exonic
CAediting_1353073chr19_40608863_+ncRNA_exonic
CAediting_1353074chr19_40609756_+exonic
CAediting_1353075chr19_40615651_+ncRNA_intronic
CAediting_1353076chr19_40616586_+ncRNA_intronic
CAediting_1353077chr19_40616612_+ncRNA_intronic
CAediting_1353078chr19_40616627_+ncRNA_intronic
CAediting_1353079chr19_40616630_+ncRNA_intronic
CAediting_1353080chr19_40617523_+ncRNA_intronic
CAediting_1353081chr19_40617541_+ncRNA_intronic
CAediting_1353082chr19_40617553_+ncRNA_intronic
CAediting_1353083chr19_40617565_+ncRNA_intronic
CAediting_1353084chr19_40617569_+ncRNA_intronic
CAediting_1353085chr19_40617570_+ncRNA_intronic
CAediting_1353086chr19_40617589_+ncRNA_intronic
CAediting_1353087chr19_40617594_+ncRNA_intronic
CAediting_1353088chr19_40618334_+ncRNA_intronic
CAediting_1353089chr19_40618340_+ncRNA_intronic
CAediting_1353090chr19_40618360_+ncRNA_intronic
CAediting_1353091chr19_40618377_+ncRNA_intronic
CAediting_1353092chr19_40618538_+ncRNA_intronic
CAediting_1353093chr19_40620259_+ncRNA_intronic
CAediting_1353094chr19_40620260_+ncRNA_intronic
CAediting_1353095chr19_40620264_+ncRNA_intronic
CAediting_1353096chr19_40620325_+ncRNA_intronic
CAediting_1353097chr19_40620338_+ncRNA_intronic
CAediting_1353098chr19_40620339_+ncRNA_intronic
CAediting_1353099chr19_40620342_+ncRNA_intronic
CAediting_1353100chr19_40620350_+ncRNA_intronic
CAediting_1353101chr19_40620356_+ncRNA_intronic
CAediting_1353102chr19_40620369_+ncRNA_intronic
CAediting_1353103chr19_40620394_+ncRNA_intronic
CAediting_1353104chr19_40620561_+ncRNA_intronic
CAediting_1353105chr19_40620566_+ncRNA_intronic
CAediting_1353106chr19_40620577_+ncRNA_intronic
CAediting_1353107chr19_40620597_+ncRNA_intronic
CAediting_1353108chr19_40620598_+ncRNA_intronic
CAediting_1353109chr19_40620599_+ncRNA_intronic
CAediting_1353110chr19_40620600_+ncRNA_intronic
CAediting_1353111chr19_40620611_+ncRNA_intronic
CAediting_1353112chr19_40620614_+ncRNA_intronic
CAediting_1353113chr19_40620615_+ncRNA_intronic
CAediting_1353114chr19_40620616_+ncRNA_intronic
CAediting_1353115chr19_40620617_+ncRNA_intronic
CAediting_1353116chr19_40620618_+ncRNA_intronic
CAediting_1353117chr19_40620620_+ncRNA_intronic
CAediting_1353118chr19_40620623_+ncRNA_intronic
CAediting_1353119chr19_40620625_+ncRNA_intronic
CAediting_1353120chr19_40620626_+ncRNA_intronic
CAediting_1353121chr19_40620629_+ncRNA_intronic
CAediting_1353122chr19_40620639_+ncRNA_intronic
CAediting_1353123chr19_40620655_+ncRNA_intronic
CAediting_1353124chr19_40620656_+ncRNA_intronic
CAediting_1353125chr19_40620671_+ncRNA_intronic
CAediting_1353126chr19_40620672_+ncRNA_intronic
CAediting_1353127chr19_40620678_+ncRNA_intronic
CAediting_1353128chr19_40620682_+ncRNA_intronic
CAediting_1353129chr19_40620686_+ncRNA_intronic
CAediting_1353130chr19_40620687_+ncRNA_intronic
CAediting_1353131chr19_40620688_+ncRNA_intronic
CAediting_1353132chr19_40620696_+ncRNA_intronic
CAediting_1353133chr19_40620701_+ncRNA_intronic
CAediting_1353134chr19_40620725_+ncRNA_intronic
CAediting_1353135chr19_40620738_+ncRNA_intronic
CAediting_1353136chr19_40620752_+ncRNA_intronic
CAediting_1353137chr19_40620755_+ncRNA_intronic
CAediting_1353138chr19_40620990_+ncRNA_intronic
CAediting_1353139chr19_40621081_+ncRNA_intronic
CAediting_1353140chr19_40621117_+ncRNA_intronic
CAediting_1353141chr19_40621123_+ncRNA_intronic
CAediting_1353142chr19_40621140_+ncRNA_intronic
CAediting_1353143chr19_40621145_+ncRNA_intronic
CAediting_1353144chr19_40621164_+ncRNA_intronic
CAediting_1353145chr19_40621177_+ncRNA_intronic
CAediting_1353146chr19_40621772_+ncRNA_intronic
CAediting_1353147chr19_40621829_+ncRNA_intronic
CAediting_1353148chr19_40621847_+ncRNA_intronic
CAediting_1353149chr19_40621887_+ncRNA_intronic
CAediting_1353150chr19_40621984_+ncRNA_intronic
CAediting_1353151chr19_40622011_+ncRNA_intronic
CAediting_1353152chr19_40623249_+ncRNA_intronic
CAediting_1353153chr19_40623375_+ncRNA_intronic
CAediting_1353154chr19_40623386_+ncRNA_intronic
CAediting_1353155chr19_40623404_+ncRNA_intronic
CAediting_1353156chr19_40623455_+ncRNA_intronic
CAediting_1353157chr19_40623458_+ncRNA_intronic
CAediting_1353158chr19_40628446_+ncRNA_intronic
CAediting_1353159chr19_40628463_+ncRNA_intronic
CAediting_1353160chr19_40628873_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1353041chr19_40606881_+SINEAluAluSz
CAediting_1353042chr19_40606951_+SINEAluAluSz
CAediting_1353043chr19_40606971_+SINEAluAluSz
CAediting_1353044chr19_40607012_+SINEAluAluSz
CAediting_1353045chr19_40607025_+SINEAluAluSz
CAediting_1353046chr19_40607033_+SINEAluAluSz
CAediting_1353047chr19_40608649_+SINEAluAluSq2
CAediting_1353048chr19_40608657_+SINEAluAluSq2
CAediting_1353049chr19_40608658_+SINEAluAluSq2
CAediting_1353050chr19_40608663_+SINEAluAluSq2
CAediting_1353051chr19_40608704_+SINEAluAluSq2
CAediting_1353052chr19_40608710_+SINEAluAluSq2
CAediting_1353053chr19_40608724_+SINEAluAluSq2
CAediting_1353054chr19_40608725_+SINEAluAluSq2
CAediting_1353055chr19_40608727_+SINEAluAluSq2
CAediting_1353056chr19_40608733_+SINEAluAluSq2
CAediting_1353057chr19_40608734_+SINEAluAluSq2
CAediting_1353058chr19_40608735_+SINEAluAluSq2
CAediting_1353059chr19_40608746_+SINEAluAluSq2
CAediting_1353060chr19_40608755_+SINEAluAluSq2
CAediting_1353061chr19_40608761_+SINEAluAluSq2
CAediting_1353062chr19_40608790_+SINEAluAluSq2
CAediting_1353063chr19_40608791_+SINEAluAluSq2
CAediting_1353064chr19_40608796_+SINEAluAluSq2
CAediting_1353065chr19_40608823_+SINEAluAluSq2
CAediting_1353066chr19_40608826_+SINEAluAluSq2
CAediting_1353067chr19_40608836_+SINEAluAluSq2
CAediting_1353068chr19_40608839_+SINEAluAluSq2
CAediting_1353069chr19_40608843_+SINEAluAluSq2
CAediting_1353070chr19_40608852_+SINEAluAluSq2
CAediting_1353071chr19_40608856_+SINEAluAluSq2
CAediting_1353072chr19_40608861_+SINEAluAluSq2
CAediting_1353073chr19_40608863_+SINEAluAluSq2
CAediting_1353075chr19_40615651_+SINEAluAluSg
CAediting_1353076chr19_40616586_+SINEAluAluSz
CAediting_1353077chr19_40616612_+SINEAluAluSz
CAediting_1353078chr19_40616627_+SINEAluAluSz
CAediting_1353079chr19_40616630_+SINEAluAluSz
CAediting_1353080chr19_40617523_+SINEAluAluSz
CAediting_1353081chr19_40617541_+SINEAluAluSz
CAediting_1353082chr19_40617553_+SINEAluAluSz
CAediting_1353083chr19_40617565_+SINEAluAluSz
CAediting_1353084chr19_40617569_+SINEAluAluSz
CAediting_1353085chr19_40617570_+SINEAluAluSz
CAediting_1353086chr19_40617589_+SINEAluAluSz
CAediting_1353087chr19_40617594_+SINEAluAluSz
CAediting_1353088chr19_40618334_+SINEAluAluSq2
CAediting_1353089chr19_40618340_+SINEAluAluSq2
CAediting_1353090chr19_40618360_+SINEAluAluSq2
CAediting_1353091chr19_40618377_+SINEAluAluSq2
CAediting_1353092chr19_40618538_+SINEAluAluSq2
CAediting_1353093chr19_40620259_+SINEAluAluJb
CAediting_1353094chr19_40620260_+SINEAluAluJb
CAediting_1353095chr19_40620264_+SINEAluAluJb
CAediting_1353096chr19_40620325_+SINEAluAluJb
CAediting_1353097chr19_40620338_+SINEAluAluJb
CAediting_1353098chr19_40620339_+SINEAluAluJb
CAediting_1353099chr19_40620342_+SINEAluAluJb
CAediting_1353100chr19_40620350_+SINEAluAluJb
CAediting_1353101chr19_40620356_+SINEAluAluJb
CAediting_1353102chr19_40620369_+SINEAluAluJb
CAediting_1353103chr19_40620394_+SINEAluAluJb
CAediting_1353104chr19_40620561_+SINEAluAluSx
CAediting_1353105chr19_40620566_+SINEAluAluSx
CAediting_1353106chr19_40620577_+SINEAluAluSx
CAediting_1353107chr19_40620597_+SINEAluAluSx
CAediting_1353108chr19_40620598_+SINEAluAluSx
CAediting_1353109chr19_40620599_+SINEAluAluSx
CAediting_1353110chr19_40620600_+SINEAluAluSx
CAediting_1353111chr19_40620611_+SINEAluAluSx
CAediting_1353112chr19_40620614_+SINEAluAluSx
CAediting_1353113chr19_40620615_+SINEAluAluSx
CAediting_1353114chr19_40620616_+SINEAluAluSx
CAediting_1353115chr19_40620617_+SINEAluAluSx
CAediting_1353116chr19_40620618_+SINEAluAluSx
CAediting_1353117chr19_40620620_+SINEAluAluSx
CAediting_1353118chr19_40620623_+SINEAluAluSx
CAediting_1353119chr19_40620625_+SINEAluAluSx
CAediting_1353120chr19_40620626_+SINEAluAluSx
CAediting_1353121chr19_40620629_+SINEAluAluSx
CAediting_1353122chr19_40620639_+SINEAluAluSx
CAediting_1353123chr19_40620655_+SINEAluAluSx
CAediting_1353124chr19_40620656_+SINEAluAluSx
CAediting_1353125chr19_40620671_+SINEAluAluSx
CAediting_1353126chr19_40620672_+SINEAluAluSx
CAediting_1353127chr19_40620678_+SINEAluAluSx
CAediting_1353128chr19_40620682_+SINEAluAluSx
CAediting_1353129chr19_40620686_+SINEAluAluSx
CAediting_1353130chr19_40620687_+SINEAluAluSx
CAediting_1353131chr19_40620688_+SINEAluAluSx
CAediting_1353132chr19_40620696_+SINEAluAluSx
CAediting_1353133chr19_40620701_+SINEAluAluSx
CAediting_1353134chr19_40620725_+SINEAluAluSx
CAediting_1353135chr19_40620738_+SINEAluAluSx
CAediting_1353136chr19_40620752_+SINEAluAluSx
CAediting_1353137chr19_40620755_+SINEAluAluSx
CAediting_1353138chr19_40620990_+SINEAluAluSq
CAediting_1353139chr19_40621081_+SINEAluAluSq
CAediting_1353140chr19_40621117_+SINEAluAluSq
CAediting_1353141chr19_40621123_+SINEAluAluSq
CAediting_1353142chr19_40621140_+SINEAluAluSq
CAediting_1353143chr19_40621145_+SINEAluAluSq
CAediting_1353144chr19_40621164_+SINEAluAluSq
CAediting_1353145chr19_40621177_+SINEAluAluSq
CAediting_1353146chr19_40621772_+SINEAluAluSz
CAediting_1353147chr19_40621829_+SINEAluAluSz
CAediting_1353148chr19_40621847_+SINEAluAluSz
CAediting_1353149chr19_40621887_+SINEAluAluSz
CAediting_1353150chr19_40621984_+SINEAluAluSz
CAediting_1353151chr19_40622011_+SINEAluAluSz
CAediting_1353152chr19_40623249_+SINEAluAluSq2
CAediting_1353153chr19_40623375_+SINEAluAluSq2
CAediting_1353154chr19_40623386_+SINEAluAluSq2
CAediting_1353155chr19_40623404_+SINEAluAluSq2
CAediting_1353156chr19_40623455_+SINEAluAluSq2
CAediting_1353157chr19_40623458_+SINEAluAluSq2
CAediting_1353158chr19_40628446_+SINEAluAluSq2
CAediting_1353159chr19_40628463_+SINEAluAluSq2
CAediting_1353160chr19_40628873_+SINEAluAluSx1

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RNA A-to-I editing events in the alternative splicing sites for LTBP4

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000090006.16.LTBP4.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000090006.16.LTBP4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LTBP4

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for LTBP4

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for LTBP4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000090006.16ENST00000204005hsa-miR-605-3p40629769406297757mer-m84062975640629776145-15.79
CAediting_748296chr10_51299626_+ENSG00000090006.16ENST00000243562hsa-miR-605-3p40629769406297757mer-m84062975640629776145-15.79
CAediting_748296chr10_51299626_+ENSG00000090006.16ENST00000598166hsa-miR-605-3p40629769406297757mer-m84062975640629776145-15.79
CAediting_77128chr1_85133844_+ENSG00000090006.16ENST00000600026hsa-miR-4423-3p40599494405995007mer-m84059948140599501140-14.13
CAediting_1054808chr15_66496985_-ENSG00000090006.16ENST00000600026hsa-miR-451240600168406001747mer-m84060015440600175141-22.26
CAediting_1054808chr15_66496985_-ENSG00000090006.16ENST00000600026hsa-miR-451240600140406001467mer-m84060012840600147150-22.26
CAediting_580943chr7_100356700_+ENSG00000090006.16ENST00000204005hsa-miR-6840-3p40629739406297457mer-m84062972540629746149-30.6
CAediting_77128chr1_85133844_+ENSG00000090006.16ENST00000599016hsa-miR-4423-3p40599494405995007mer-m84059948140599501140-14.13
CAediting_1054808chr15_66496985_-ENSG00000090006.16ENST00000599016hsa-miR-451240600168406001747mer-m84060015440600175141-22.26
CAediting_1054808chr15_66496985_-ENSG00000090006.16ENST00000599016hsa-miR-451240600140406001467mer-m84060012840600147150-22.26
CAediting_77128chr1_85133844_+ENSG00000090006.16ENST00000594537hsa-miR-4423-3p40599494405995007mer-m84059948140599501140-14.13
CAediting_1054808chr15_66496985_-ENSG00000090006.16ENST00000594537hsa-miR-451240600168406001747mer-m84060015440600175141-22.26
CAediting_1054808chr15_66496985_-ENSG00000090006.16ENST00000594537hsa-miR-451240600140406001467mer-m84060012840600147150-22.26
CAediting_580943chr7_100356700_+ENSG00000090006.16ENST00000243562hsa-miR-6840-3p40629739406297457mer-m84062972540629746149-30.6
CAediting_580943chr7_100356700_+ENSG00000090006.16ENST00000598166hsa-miR-6840-3p40629739406297457mer-m84062972540629746149-30.6
CAediting_1524209chrX_134546392_-ENSG00000090006.16ENST00000600026hsa-miR-503-5p40605084406050907mer-m84060506840605091152-26.54
CAediting_1524209chrX_134546392_-ENSG00000090006.16ENST00000599016hsa-miR-503-5p40605084406050907mer-m84060506840605091152-26.54
CAediting_1524209chrX_134546392_-ENSG00000090006.16ENST00000594537hsa-miR-503-5p40605084406050907mer-m84060506840605091152-26.54

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for LTBP4

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for LTBP4

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for LTBP4

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for LTBP4

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for LTBP4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for LTBP4

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
LTBP4C2750804Cutis Laxa With Severe Pulmonary, Gastrointestinal, And Urinary Abnormalities3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
LTBP4C0010495Cutis Laxa1GENOMICS_ENGLAND
LTBP4C0013264Muscular Dystrophy, Duchenne1ORPHANET
LTBP4C0017636Glioblastoma1CTD_human
LTBP4C0027643Neoplasm Recurrence, Local1CTD_human
LTBP4C0334588Giant Cell Glioblastoma1CTD_human
LTBP4C1621958Glioblastoma Multiforme1CTD_human