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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: TMEM126A (CAeditome ID:84233) |
Gene summary for TMEM126A |
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Gene information | Gene symbol | TMEM126A | Gene ID | 84233 |
Gene name | transmembrane protein 126A | |
Synonyms | OPA7 | |
Cytomap | 11q14.1 | |
Type of gene | protein-coding | |
Description | transmembrane protein 126A | |
Modification date | 20210518 | |
UniProtAcc | Q9H061 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
TMEM126A | GO:0005739 | Transmembrane protein 126A | 0000054 |
TMEM126A | GO:0005739 | Transmembrane protein 126A | 19327736 |
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RNA A-to-I events for TMEM126A |
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CAediting_845261(85656318, +), CAediting_845262(85656341, +), |
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RNA editing positional annotations for TMEM126A using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_845262 | chr11_85656341_+ | nonsynonymous SNV | ENST00000304511.5 | c.A428G | p.N143S | D | B | D |
CAediting_845262 | chr11_85656341_+ | nonsynonymous SNV | ENST00000528105.4 | c.A218G | p.N73S | D | B | D |
CAediting_845262 | chr11_85656341_+ | nonsynonymous SNV | ENST00000532180.1 | c.A218G | p.N73S | D | B | D |
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CAeditome ID | Position | Variant type |
CAediting_845261 | chr11_85656318_+ | exonic |
CAediting_845262 | chr11_85656341_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for TMEM126A |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TMEM126A |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for TMEM126A |
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The effects of the RNA editing to the miRNA binding sites for TMEM126A |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000525353 | hsa-miR-4287 | 85656334 | 85656340 | 7mer-m8 | 85656321 | 85656341 | 141.00 | -15.07 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000525353 | hsa-miR-4685-3p | 85656334 | 85656340 | 7mer-m8 | 85656320 | 85656341 | 147.00 | -15.82 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000525353 | hsa-miR-7106-3p | 85656335 | 85656342 | 8mer-1a | 85656320 | 85656342 | 140.00 | -16.47 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000531366 | hsa-miR-4287 | 85656334 | 85656340 | 7mer-m8 | 85656321 | 85656341 | 141.00 | -15.07 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000531366 | hsa-miR-4685-3p | 85656334 | 85656340 | 7mer-m8 | 85656320 | 85656341 | 147.00 | -15.82 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000531366 | hsa-miR-7106-3p | 85656335 | 85656342 | 8mer-1a | 85656320 | 85656342 | 140.00 | -16.47 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000525353 | hsa-miR-4755-5p | 85656334 | 85656340 | 7mer-m8 | 85656320 | 85656341 | 140 | -10.84 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000525353 | hsa-miR-5006-3p | 85656334 | 85656340 | 7mer-m8 | 85656321 | 85656341 | 147 | -13.94 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000525353 | hsa-miR-642b-5p | 85656335 | 85656342 | 8mer-1a | 85656321 | 85656342 | 142 | -14.61 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000531366 | hsa-miR-4755-5p | 85656334 | 85656340 | 7mer-m8 | 85656320 | 85656341 | 140 | -10.84 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000531366 | hsa-miR-5006-3p | 85656334 | 85656340 | 7mer-m8 | 85656321 | 85656341 | 147 | -13.94 |
CAediting_845262 | chr11_85656341_+ | ENSG00000171202.5 | ENST00000531366 | hsa-miR-642b-5p | 85656335 | 85656342 | 8mer-1a | 85656321 | 85656342 | 142 | -14.61 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_980496 | chr14_31014685_- | ENSG00000171202.5 | ENST00000525353 | hsa-miR-624-3p | 85655662 | 85655668 | 7mer-m8 | 85655648 | 85655669 | 157 | -21.46 |
CAediting_980496 | chr14_31014685_- | ENSG00000171202.5 | ENST00000531366 | hsa-miR-624-3p | 85655662 | 85655668 | 7mer-m8 | 85655648 | 85655669 | 157 | -21.46 |
CAediting_1229414 | chr17_67471546_+ | ENSG00000171202.5 | ENST00000525353 | hsa-miR-548aa | 85655639 | 85655645 | 7mer-m8 | 85655618 | 85655646 | 149 | -15.28 |
CAediting_1229414 | chr17_67471546_+ | ENSG00000171202.5 | ENST00000531366 | hsa-miR-548aa | 85655639 | 85655645 | 7mer-m8 | 85655623 | 85655646 | 149 | -14.05 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for TMEM126A |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for TMEM126A |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for TMEM126A |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for TMEM126A |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for TMEM126A |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TMEM126A |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
TMEM126A | C2751812 | OPTIC ATROPHY 7 (disorder) | 3 | CTD_human;GENOMICS_ENGLAND;ORPHANET |