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Editing gene: POLR1B (CAeditome ID:84172)

Gene summary for POLR1B

Gene summary

Gene information	Gene symbol	POLR1B
	Gene ID	84172
	Gene name	RNA polymerase I subunit B
	Synonyms	A135\|RPA135\|RPA2\|Rpo1-2\|TCS4
	Cytomap	2q14.1
	Type of gene	protein-coding
	Description	DNA-directed RNA polymerase I subunit RPA2DNA-directed RNA polymerase I 135 kDa polypeptideDNA-directed RNA polymerase I 135kDa polypeptideRNA polymerase I subunit 2polymerase (RNA) I polypeptide B, 128kDapolymerase (RNA) I subunit B
	Modification date	20210518
	UniProtAcc	Q9H9Y6
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
POLR1B	GO:0005730	DNA-directed RNA polymerase I subunit RPA2	0000052
POLR1B	GO:0005829	DNA-directed RNA polymerase I subunit RPA2	0000052

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RNA A-to-I events for POLR1B

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000125630.14

RNA A-to-I editing events in Cancer.

CAediting_207738(112544004, +), CAediting_207739(112545691, +), CAediting_207740(112545719, +), CAediting_207741(112545740, +), CAediting_207742(112545744, +), CAediting_207743(112545875, +), CAediting_207744(112545881, +), CAediting_207745(112547931, +), CAediting_207746(112548656, +), CAediting_207747(112553430, +), CAediting_207748(112554785, +), CAediting_207749(112554786, +), CAediting_207750(112554826, +), CAediting_207751(112554841, +), CAediting_207752(112557045, +), CAediting_207753(112557092, +), CAediting_207754(112557179, +), CAediting_207755(112557591, +), CAediting_207756(112557598, +), CAediting_207757(112557600, +), CAediting_207758(112557676, +), CAediting_207759(112557677, +), CAediting_207760(112560801, +), CAediting_207761(112560870, +), CAediting_207762(112560881, +), CAediting_207763(112560918, +), CAediting_207764(112560958, +), CAediting_207765(112560962, +), CAediting_207766(112561877, +), CAediting_207767(112561907, +), CAediting_207768(112563707, +), CAediting_207769(112563884, +), CAediting_207770(112574119, +), CAediting_207771(112574451, +), CAediting_207772(112574489, +), CAediting_207773(112574504, +), CAediting_207774(112574585, +), CAediting_207775(112574595, +), CAediting_207776(112574611, +), CAediting_207777(112574643, +), CAediting_207778(112574663, +), CAediting_207779(112576642, +), CAediting_207780(112576645, +), CAediting_207781(112576664, +), CAediting_207782(112576668, +), CAediting_207783(112576690, +), CAediting_207784(112576705, +), CAediting_207785(112576720, +), CAediting_207786(112576731, +), CAediting_207787(112576781, +), CAediting_207788(112576782, +), CAediting_207789(112576784, +), CAediting_207790(112576790, +), CAediting_207791(112576795, +), CAediting_207792(112576800, +), CAediting_207793(112576829, +), CAediting_207794(112576835, +), CAediting_207795(112576837, +), CAediting_207796(112576844, +),

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RNA editing positional annotations for POLR1B using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_207738	chr2_112544004_+	ncRNA_intronic
CAediting_207739	chr2_112545691_+	ncRNA_intronic
CAediting_207740	chr2_112545719_+	ncRNA_intronic
CAediting_207741	chr2_112545740_+	ncRNA_intronic
CAediting_207742	chr2_112545744_+	ncRNA_intronic
CAediting_207743	chr2_112545875_+	exonic
CAediting_207744	chr2_112545881_+	ncRNA_intronic
CAediting_207745	chr2_112547931_+	ncRNA_intronic
CAediting_207746	chr2_112548656_+	ncRNA_intronic
CAediting_207747	chr2_112553430_+	ncRNA_exonic
CAediting_207748	chr2_112554785_+	ncRNA_intronic
CAediting_207749	chr2_112554786_+	ncRNA_intronic
CAediting_207750	chr2_112554826_+	ncRNA_intronic
CAediting_207751	chr2_112554841_+	ncRNA_intronic
CAediting_207752	chr2_112557045_+	ncRNA_intronic
CAediting_207753	chr2_112557092_+	ncRNA_intronic
CAediting_207754	chr2_112557179_+	ncRNA_intronic
CAediting_207755	chr2_112557591_+	ncRNA_intronic
CAediting_207756	chr2_112557598_+	ncRNA_intronic
CAediting_207757	chr2_112557600_+	ncRNA_intronic
CAediting_207758	chr2_112557676_+	ncRNA_intronic
CAediting_207759	chr2_112557677_+	ncRNA_intronic
CAediting_207760	chr2_112560801_+	intronic
CAediting_207761	chr2_112560870_+	intronic
CAediting_207762	chr2_112560881_+	intronic
CAediting_207763	chr2_112560918_+	intronic
CAediting_207764	chr2_112560958_+	intronic
CAediting_207765	chr2_112560962_+	intronic
CAediting_207766	chr2_112561877_+	intronic
CAediting_207767	chr2_112561907_+	intronic
CAediting_207768	chr2_112563707_+	intronic
CAediting_207769	chr2_112563884_+	intronic
CAediting_207770	chr2_112574119_+	intronic
CAediting_207771	chr2_112574451_+	intronic
CAediting_207772	chr2_112574489_+	intronic
CAediting_207773	chr2_112574504_+	intronic
CAediting_207774	chr2_112574585_+	intronic
CAediting_207775	chr2_112574595_+	intronic
CAediting_207776	chr2_112574611_+	intronic
CAediting_207777	chr2_112574643_+	intronic
CAediting_207778	chr2_112574663_+	intronic
CAediting_207779	chr2_112576642_+	UTR3
CAediting_207780	chr2_112576645_+	UTR3
CAediting_207781	chr2_112576664_+	UTR3
CAediting_207782	chr2_112576668_+	UTR3
CAediting_207783	chr2_112576690_+	UTR3
CAediting_207784	chr2_112576705_+	UTR3
CAediting_207785	chr2_112576720_+	UTR3
CAediting_207786	chr2_112576731_+	UTR3
CAediting_207787	chr2_112576781_+	UTR3
CAediting_207788	chr2_112576782_+	UTR3
CAediting_207789	chr2_112576784_+	UTR3
CAediting_207790	chr2_112576790_+	UTR3
CAediting_207791	chr2_112576795_+	UTR3
CAediting_207792	chr2_112576800_+	UTR3
CAediting_207793	chr2_112576829_+	UTR3
CAediting_207794	chr2_112576835_+	UTR3
CAediting_207795	chr2_112576837_+	UTR3
CAediting_207796	chr2_112576844_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_207738	chr2_112544004_+	SINE	Alu	AluJr
CAediting_207739	chr2_112545691_+	SINE	Alu	AluJo
CAediting_207740	chr2_112545719_+	SINE	Alu	AluJo
CAediting_207741	chr2_112545740_+	SINE	Alu	AluJo
CAediting_207742	chr2_112545744_+	SINE	Alu	AluJo
CAediting_207743	chr2_112545875_+	SINE	Alu	AluJo
CAediting_207744	chr2_112545881_+	SINE	Alu	AluJo
CAediting_207745	chr2_112547931_+	SINE	Alu	AluJr
CAediting_207746	chr2_112548656_+	SINE	Alu	AluY
CAediting_207747	chr2_112553430_+	SINE	Alu	AluJb
CAediting_207748	chr2_112554785_+	SINE	Alu	AluJb
CAediting_207749	chr2_112554786_+	SINE	Alu	AluJb
CAediting_207750	chr2_112554826_+	SINE	Alu	AluJb
CAediting_207751	chr2_112554841_+	SINE	Alu	AluJb
CAediting_207752	chr2_112557045_+	SINE	Alu	AluJo
CAediting_207753	chr2_112557092_+	SINE	Alu	AluJo
CAediting_207754	chr2_112557179_+	SINE	Alu	AluJo
CAediting_207755	chr2_112557591_+	SINE	Alu	AluJr
CAediting_207756	chr2_112557598_+	SINE	Alu	AluJr
CAediting_207757	chr2_112557600_+	SINE	Alu	AluJr
CAediting_207758	chr2_112557676_+	SINE	Alu	AluJr
CAediting_207759	chr2_112557677_+	SINE	Alu	AluJr
CAediting_207760	chr2_112560801_+	SINE	Alu	AluSz
CAediting_207761	chr2_112560870_+	SINE	Alu	AluSz
CAediting_207762	chr2_112560881_+	SINE	Alu	AluSz
CAediting_207763	chr2_112560918_+	SINE	Alu	AluSz
CAediting_207764	chr2_112560958_+	SINE	Alu	AluSz
CAediting_207765	chr2_112560962_+	SINE	Alu	AluSz
CAediting_207766	chr2_112561877_+	SINE	Alu	AluJr
CAediting_207767	chr2_112561907_+	SINE	Alu	AluJr
CAediting_207768	chr2_112563707_+	SINE	Alu	AluJr
CAediting_207769	chr2_112563884_+	SINE	Alu	AluJr
CAediting_207770	chr2_112574119_+	SINE	Alu	AluJb
CAediting_207771	chr2_112574451_+	SINE	Alu	AluJb
CAediting_207772	chr2_112574489_+	SINE	Alu	AluJb
CAediting_207773	chr2_112574504_+	SINE	Alu	AluJb
CAediting_207774	chr2_112574585_+	SINE	Alu	AluJb
CAediting_207775	chr2_112574595_+	SINE	Alu	AluJb
CAediting_207776	chr2_112574611_+	SINE	Alu	AluJb
CAediting_207777	chr2_112574643_+	SINE	Alu	AluJb
CAediting_207778	chr2_112574663_+	SINE	Alu	AluJb
CAediting_207779	chr2_112576642_+	LINE	L1	L1MA10
CAediting_207780	chr2_112576645_+	LINE	L1	L1MA10
CAediting_207782	chr2_112576668_+	SINE	Alu	FLAM_A
CAediting_207783	chr2_112576690_+	SINE	Alu	FLAM_A
CAediting_207784	chr2_112576705_+	SINE	Alu	FLAM_A
CAediting_207785	chr2_112576720_+	SINE	Alu	FLAM_A
CAediting_207786	chr2_112576731_+	SINE	Alu	FLAM_A
CAediting_207787	chr2_112576781_+	SINE	Alu	AluSz
CAediting_207788	chr2_112576782_+	SINE	Alu	AluSz
CAediting_207789	chr2_112576784_+	SINE	Alu	AluSz
CAediting_207790	chr2_112576790_+	SINE	Alu	AluSz
CAediting_207791	chr2_112576795_+	SINE	Alu	AluSz
CAediting_207792	chr2_112576800_+	SINE	Alu	AluSz
CAediting_207793	chr2_112576829_+	SINE	Alu	AluSz
CAediting_207794	chr2_112576835_+	SINE	Alu	AluSz
CAediting_207795	chr2_112576837_+	SINE	Alu	AluSz
CAediting_207796	chr2_112576844_+	SINE	Alu	AluSz

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RNA A-to-I editing events in the alternative splicing sites for POLR1B

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000125630.14.POLR1B.

Correlation between RNA A-to-I editing and PSI for ENSG00000125630.14.POLR1B.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for POLR1B

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_207781.ENSG00000125630.POLR1B.png
Soverview

PCPG.CAediting_207781.ENSG00000125630.POLR1B.png
Soverview

PRAD.CAediting_207781.ENSG00000125630.POLR1B.png
Soverview

THYM.CAediting_207781.ENSG00000125630.POLR1B.png
Soverview

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Protein coding region RNA A-to-I editings for POLR1B

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for POLR1B

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000537335	hsa-miR-3176	112576662	112576668	7mer-m8	112576651	112576669	140.00	-15.07
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000537335	hsa-miR-3922-3p	112576662	112576668	7mer-m8	112576643	112576669	146.00	-19.80
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000537335	hsa-miR-519d-5p	112576657	112576663	7mer-m8	112576639	112576664	157.00	-19.82
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000537335	hsa-miR-6878-3p	112576661	112576667	7mer-m8	112576648	112576668	141.00	-17.50
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000541869	hsa-miR-3176	112576662	112576668	7mer-m8	112576651	112576669	140.00	-15.07
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000541869	hsa-miR-3922-3p	112576662	112576668	7mer-m8	112576643	112576669	146.00	-19.80
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000541869	hsa-miR-519d-5p	112576657	112576663	7mer-m8	112576639	112576664	157.00	-19.82
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000541869	hsa-miR-6878-3p	112576661	112576667	7mer-m8	112576648	112576668	141.00	-17.50
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000409894	hsa-miR-3176	112576662	112576668	7mer-m8	112576651	112576669	140.00	-15.07
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000409894	hsa-miR-3922-3p	112576662	112576668	7mer-m8	112576643	112576669	146.00	-19.80
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000409894	hsa-miR-519d-5p	112576657	112576663	7mer-m8	112576639	112576664	157.00	-19.82
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000409894	hsa-miR-6878-3p	112576661	112576667	7mer-m8	112576648	112576668	141.00	-17.50
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000537335	hsa-miR-3619-3p	112576687	112576693	7mer-m8	112576671	112576694	143.00	-20.06
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000537335	hsa-miR-591	112576687	112576692	6mer	112576674	112576693	144.00	-15.34
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000541869	hsa-miR-3619-3p	112576687	112576693	7mer-m8	112576671	112576694	143.00	-20.06
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000541869	hsa-miR-591	112576687	112576692	6mer	112576674	112576693	144.00	-15.34
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000409894	hsa-miR-3619-3p	112576687	112576693	7mer-m8	112576671	112576694	143.00	-20.06
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000409894	hsa-miR-591	112576687	112576692	6mer	112576674	112576693	144.00	-15.34
CAediting_207794	chr2_112576835_+	ENSG00000125630.14	ENST00000537335	hsa-miR-106a-3p	112576831	112576836	6mer	112576816	112576837	141.00	-21.13
CAediting_207794	chr2_112576835_+	ENSG00000125630.14	ENST00000541869	hsa-miR-106a-3p	112576831	112576836	6mer	112576816	112576837	141.00	-21.13
CAediting_207794	chr2_112576835_+	ENSG00000125630.14	ENST00000409894	hsa-miR-106a-3p	112576831	112576836	6mer	112576816	112576837	141.00	-21.13
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000537335	hsa-miR-100-5p	112576833	112576839	7mer-m8	112576818	112576840	160.00	-21.27
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000537335	hsa-miR-99a-5p	112576833	112576839	7mer-m8	112576820	112576840	155.00	-18.58
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000537335	hsa-miR-99b-5p	112576833	112576839	7mer-m8	112576820	112576840	147.00	-22.46
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000541869	hsa-miR-100-5p	112576833	112576839	7mer-m8	112576818	112576840	160.00	-21.27
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000541869	hsa-miR-99a-5p	112576833	112576839	7mer-m8	112576820	112576840	155.00	-18.58
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000541869	hsa-miR-99b-5p	112576833	112576839	7mer-m8	112576820	112576840	147.00	-22.46
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000409894	hsa-miR-100-5p	112576833	112576839	7mer-m8	112576818	112576840	160.00	-21.27
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000409894	hsa-miR-99a-5p	112576833	112576839	7mer-m8	112576820	112576840	155.00	-18.58
CAediting_207795	chr2_112576837_+	ENSG00000125630.14	ENST00000409894	hsa-miR-99b-5p	112576833	112576839	7mer-m8	112576820	112576840	147.00	-22.46
CAediting_207779	chr2_112576642_+	ENSG00000125630.14	ENST00000537335	hsa-miR-1285-5p	112576637	112576644	8mer-1a	112576624	112576644	159.00	-16.82
CAediting_207779	chr2_112576642_+	ENSG00000125630.14	ENST00000541869	hsa-miR-1285-5p	112576637	112576644	8mer-1a	112576624	112576644	159.00	-16.82
CAediting_207779	chr2_112576642_+	ENSG00000125630.14	ENST00000409894	hsa-miR-1285-5p	112576637	112576644	8mer-1a	112576624	112576644	159.00	-16.82
CAediting_207780	chr2_112576645_+	ENSG00000125630.14	ENST00000537335	hsa-miR-216a-5p	112576643	112576649	7mer-m8	112576630	112576650	146.00	-15.59
CAediting_207780	chr2_112576645_+	ENSG00000125630.14	ENST00000541869	hsa-miR-216a-5p	112576643	112576649	7mer-m8	112576630	112576650	146.00	-15.59
CAediting_207780	chr2_112576645_+	ENSG00000125630.14	ENST00000409894	hsa-miR-216a-5p	112576643	112576649	7mer-m8	112576630	112576650	146.00	-15.59
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000537335	hsa-miR-150-5p	112576701	112576707	7mer-m8	112576687	112576708	140.00	-14.76
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000537335	hsa-miR-6778-3p	112576703	112576709	7mer-m8	112576690	112576710	145.00	-15.43
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000541869	hsa-miR-150-5p	112576701	112576707	7mer-m8	112576687	112576708	140.00	-14.76
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000541869	hsa-miR-6778-3p	112576703	112576709	7mer-m8	112576690	112576710	145.00	-15.43
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000409894	hsa-miR-150-5p	112576701	112576707	7mer-m8	112576687	112576708	140.00	-14.76
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000409894	hsa-miR-6778-3p	112576703	112576709	7mer-m8	112576690	112576710	145.00	-15.43
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000537335	hsa-miR-515-5p	112576777	112576783	7mer-m8	112576762	112576784	152.00	-17.50
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000537335	hsa-miR-515-5p	112576777	112576783	7mer-m8	112576762	112576784	152.00	-17.50
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000537335	hsa-miR-519e-5p	112576777	112576783	7mer-m8	112576764	112576784	150.00	-18.87
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000537335	hsa-miR-5695	112576776	112576783	8mer-1a	112576761	112576783	155.00	-16.13
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000541869	hsa-miR-515-5p	112576777	112576783	7mer-m8	112576762	112576784	152.00	-17.50
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000541869	hsa-miR-515-5p	112576777	112576783	7mer-m8	112576762	112576784	152.00	-17.50
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000541869	hsa-miR-519e-5p	112576777	112576783	7mer-m8	112576764	112576784	150.00	-18.87
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000541869	hsa-miR-5695	112576776	112576783	8mer-1a	112576761	112576783	155.00	-16.13
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000409894	hsa-miR-515-5p	112576777	112576783	7mer-m8	112576762	112576784	152.00	-17.50
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000409894	hsa-miR-515-5p	112576777	112576783	7mer-m8	112576762	112576784	152.00	-17.50
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000409894	hsa-miR-519e-5p	112576777	112576783	7mer-m8	112576764	112576784	150.00	-18.87
CAediting_207787	chr2_112576781_+	ENSG00000125630.14	ENST00000409894	hsa-miR-5695	112576776	112576783	8mer-1a	112576761	112576783	155.00	-16.13
CAediting_207789	chr2_112576784_+	ENSG00000125630.14	ENST00000537335	hsa-miR-3918	112576782	112576789	8mer-1a	112576767	112576789	148.00	-21.72
CAediting_207789	chr2_112576784_+	ENSG00000125630.14	ENST00000537335	hsa-miR-4512	112576781	112576787	7mer-m8	112576766	112576788	143.00	-19.52
CAediting_207789	chr2_112576784_+	ENSG00000125630.14	ENST00000541869	hsa-miR-3918	112576782	112576789	8mer-1a	112576767	112576789	148.00	-21.72
CAediting_207789	chr2_112576784_+	ENSG00000125630.14	ENST00000541869	hsa-miR-4512	112576781	112576787	7mer-m8	112576766	112576788	143.00	-19.52
CAediting_207789	chr2_112576784_+	ENSG00000125630.14	ENST00000409894	hsa-miR-3918	112576782	112576789	8mer-1a	112576767	112576789	148.00	-21.72
CAediting_207789	chr2_112576784_+	ENSG00000125630.14	ENST00000409894	hsa-miR-4512	112576781	112576787	7mer-m8	112576766	112576788	143.00	-19.52
CAediting_207793	chr2_112576829_+	ENSG00000125630.14	ENST00000537335	hsa-miR-383-3p	112576822	112576828	7mer-m8	112576811	112576829	142.00	-16.50
CAediting_207793	chr2_112576829_+	ENSG00000125630.14	ENST00000537335	hsa-miR-7977	112576825	112576831	7mer-m8	112576815	112576832	140.00	-14.19
CAediting_207793	chr2_112576829_+	ENSG00000125630.14	ENST00000541869	hsa-miR-383-3p	112576822	112576828	7mer-m8	112576811	112576829	142.00	-16.50
CAediting_207793	chr2_112576829_+	ENSG00000125630.14	ENST00000541869	hsa-miR-7977	112576825	112576831	7mer-m8	112576815	112576832	140.00	-14.19
CAediting_207793	chr2_112576829_+	ENSG00000125630.14	ENST00000409894	hsa-miR-383-3p	112576822	112576828	7mer-m8	112576811	112576829	142.00	-16.50
CAediting_207793	chr2_112576829_+	ENSG00000125630.14	ENST00000409894	hsa-miR-7977	112576825	112576831	7mer-m8	112576815	112576832	140.00	-14.19
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000537335	hsa-miR-663b	112576842	112576848	7mer-m8	112576824	112576849	148.00	-27.79
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000541869	hsa-miR-663b	112576842	112576848	7mer-m8	112576824	112576849	148.00	-27.79
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000409894	hsa-miR-663b	112576842	112576848	7mer-m8	112576824	112576849	148.00	-27.79
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000537335	hsa-miR-1255b-2-3p	112576794	112576800	7mer-m8	112576780	112576801	140.00	-8.70
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000537335	hsa-miR-4776-5p	112576797	112576803	7mer-m8	112576781	112576804	150.00	-28.33
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000537335	hsa-miR-4776-5p	112576797	112576803	7mer-m8	112576781	112576804	150.00	-28.33
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000537335	hsa-miR-4800-5p	112576798	112576804	7mer-m8	112576785	112576805	144.00	-23.05
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000541869	hsa-miR-1255b-2-3p	112576794	112576800	7mer-m8	112576780	112576801	140.00	-8.70
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000541869	hsa-miR-4776-5p	112576797	112576803	7mer-m8	112576781	112576804	150.00	-28.33
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000541869	hsa-miR-4776-5p	112576797	112576803	7mer-m8	112576781	112576804	150.00	-28.33
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000541869	hsa-miR-4800-5p	112576798	112576804	7mer-m8	112576785	112576805	144.00	-23.05
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000409894	hsa-miR-1255b-2-3p	112576794	112576800	7mer-m8	112576780	112576801	140.00	-8.70
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000409894	hsa-miR-4776-5p	112576797	112576803	7mer-m8	112576781	112576804	150.00	-28.33
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000409894	hsa-miR-4776-5p	112576797	112576803	7mer-m8	112576781	112576804	150.00	-28.33
CAediting_207792	chr2_112576800_+	ENSG00000125630.14	ENST00000409894	hsa-miR-4800-5p	112576798	112576804	7mer-m8	112576785	112576805	144.00	-23.05

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000537335	hsa-miR-10525-3p	112576687	112576692	6mer	112576672	112576693	144	-18.98
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000537335	hsa-miR-2115-5p	112576659	112576665	7mer-m8	112576645	112576666	146	-15.23
CAediting_207782	chr2_112576668_+	ENSG00000125630.14	ENST00000537335	hsa-miR-221-5p	112576664	112576669	6mer	112576649	112576670	140	-15.28
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000537335	hsa-miR-3156-3p	112576714	112576719	6mer	112576702	112576720	143	-27.4
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000537335	hsa-miR-3156-3p	112576714	112576719	6mer	112576702	112576720	143	-27.4
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000537335	hsa-miR-342-3p	112576838	112576844	7mer-m8	112576819	112576845	153	-18.11
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000537335	hsa-miR-3671	112576698	112576704	7mer-m8	112576681	112576705	153	-15.23
CAediting_207786	chr2_112576731_+	ENSG00000125630.14	ENST00000537335	hsa-miR-372-5p	112576725	112576731	7mer-m8	112576710	112576732	145	-13.37
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000537335	hsa-miR-4284	112576840	112576847	8mer-1a	112576830	112576847	151	-19.56
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000537335	hsa-miR-514b-5p	112576701	112576706	6mer	112576686	112576707	143	-16.69
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000537335	hsa-miR-532-3p	112576714	112576720	7mer-m8	112576702	112576721	147	-22.78
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000537335	hsa-miR-625-3p	112576685	112576691	7mer-m8	112576671	112576692	145	-13.77
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000537335	hsa-miR-6749-3p	112576716	112576722	7mer-m8	112576704	112576723	150	-23.12
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000537335	hsa-miR-8052	112576689	112576694	6mer	112576675	112576695	149	-26.42
CAediting_207786	chr2_112576731_+	ENSG00000125630.14	ENST00000537335	hsa-miR-888-5p	112576726	112576732	7mer-m8	112576711	112576733	144	-13.61
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000541869	hsa-miR-10525-3p	112576687	112576692	6mer	112576672	112576693	144	-18.98
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000541869	hsa-miR-2115-5p	112576659	112576665	7mer-m8	112576645	112576666	146	-15.23
CAediting_207782	chr2_112576668_+	ENSG00000125630.14	ENST00000541869	hsa-miR-221-5p	112576664	112576669	6mer	112576649	112576670	140	-15.28
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000541869	hsa-miR-3156-3p	112576714	112576719	6mer	112576702	112576720	143	-27.4
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000541869	hsa-miR-3156-3p	112576714	112576719	6mer	112576702	112576720	143	-27.4
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000541869	hsa-miR-342-3p	112576838	112576844	7mer-m8	112576819	112576845	153	-18.11
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000541869	hsa-miR-3671	112576698	112576704	7mer-m8	112576681	112576705	153	-15.23
CAediting_207786	chr2_112576731_+	ENSG00000125630.14	ENST00000541869	hsa-miR-372-5p	112576725	112576731	7mer-m8	112576710	112576732	145	-13.37
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000541869	hsa-miR-4284	112576840	112576847	8mer-1a	112576830	112576847	151	-19.56
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000541869	hsa-miR-514b-5p	112576701	112576706	6mer	112576686	112576707	143	-16.69
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000541869	hsa-miR-532-3p	112576714	112576720	7mer-m8	112576702	112576721	147	-22.78
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000541869	hsa-miR-625-3p	112576685	112576691	7mer-m8	112576671	112576692	145	-13.77
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000541869	hsa-miR-6749-3p	112576716	112576722	7mer-m8	112576704	112576723	150	-23.12
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000541869	hsa-miR-8052	112576689	112576694	6mer	112576675	112576695	149	-26.42
CAediting_207786	chr2_112576731_+	ENSG00000125630.14	ENST00000541869	hsa-miR-888-5p	112576726	112576732	7mer-m8	112576711	112576733	144	-13.61
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000409894	hsa-miR-10525-3p	112576687	112576692	6mer	112576672	112576693	144	-18.98
CAediting_207781	chr2_112576664_+	ENSG00000125630.14	ENST00000409894	hsa-miR-2115-5p	112576659	112576665	7mer-m8	112576645	112576666	146	-15.23
CAediting_207782	chr2_112576668_+	ENSG00000125630.14	ENST00000409894	hsa-miR-221-5p	112576664	112576669	6mer	112576649	112576670	140	-15.28
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000409894	hsa-miR-3156-3p	112576714	112576719	6mer	112576702	112576720	143	-27.4
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000409894	hsa-miR-3156-3p	112576714	112576719	6mer	112576702	112576720	143	-27.4
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000409894	hsa-miR-342-3p	112576838	112576844	7mer-m8	112576819	112576845	153	-18.11
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000409894	hsa-miR-3671	112576698	112576704	7mer-m8	112576681	112576705	153	-15.23
CAediting_207786	chr2_112576731_+	ENSG00000125630.14	ENST00000409894	hsa-miR-372-5p	112576725	112576731	7mer-m8	112576710	112576732	145	-13.37
CAediting_207796	chr2_112576844_+	ENSG00000125630.14	ENST00000409894	hsa-miR-4284	112576840	112576847	8mer-1a	112576830	112576847	151	-19.56
CAediting_207784	chr2_112576705_+	ENSG00000125630.14	ENST00000409894	hsa-miR-514b-5p	112576701	112576706	6mer	112576686	112576707	143	-16.69
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000409894	hsa-miR-532-3p	112576714	112576720	7mer-m8	112576702	112576721	147	-22.78
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000409894	hsa-miR-625-3p	112576685	112576691	7mer-m8	112576671	112576692	145	-13.77
CAediting_207785	chr2_112576720_+	ENSG00000125630.14	ENST00000409894	hsa-miR-6749-3p	112576716	112576722	7mer-m8	112576704	112576723	150	-23.12
CAediting_207783	chr2_112576690_+	ENSG00000125630.14	ENST00000409894	hsa-miR-8052	112576689	112576694	6mer	112576675	112576695	149	-26.42
CAediting_207786	chr2_112576731_+	ENSG00000125630.14	ENST00000409894	hsa-miR-888-5p	112576726	112576732	7mer-m8	112576711	112576733	144	-13.61

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000125630.14	ENST00000537335	hsa-miR-624-3p	112576769	112576775	7mer-m8	112576754	112576776	162	-21.62
CAediting_980496	chr14_31014685_-	ENSG00000125630.14	ENST00000537335	hsa-miR-624-3p	112576545	112576551	7mer-m8	112576532	112576552	145	-14.94
CAediting_980496	chr14_31014685_-	ENSG00000125630.14	ENST00000541869	hsa-miR-624-3p	112576769	112576775	7mer-m8	112576754	112576776	162	-21.62
CAediting_980496	chr14_31014685_-	ENSG00000125630.14	ENST00000541869	hsa-miR-624-3p	112576545	112576551	7mer-m8	112576532	112576552	145	-14.94
CAediting_980496	chr14_31014685_-	ENSG00000125630.14	ENST00000333990	hsa-miR-624-3p	112564413	112564419	7mer-m8	112564399	112564420	148	-15.3
CAediting_980496	chr14_31014685_-	ENSG00000125630.14	ENST00000409894	hsa-miR-624-3p	112576769	112576775	7mer-m8	112576754	112576776	162	-21.62
CAediting_980496	chr14_31014685_-	ENSG00000125630.14	ENST00000409894	hsa-miR-624-3p	112576545	112576551	7mer-m8	112576532	112576552	145	-14.94
CAediting_1229415	chr17_67471547_+	ENSG00000125630.14	ENST00000537335	hsa-miR-548aa	112576899	112576905	7mer-m8	112576882	112576906	140	-8.86
CAediting_86358	chr1_109598906_+	ENSG00000125630.14	ENST00000537335	hsa-miR-197-5p	112576800	112576807	8mer-1a	112576779	112576807	145	-26.04
CAediting_228905	chr2_188297554_+	ENSG00000125630.14	ENST00000537335	hsa-miR-561-3p	112575841	112575846	6mer	112575825	112575847	155	-15.47
CAediting_396018	chr5_1062918_-	ENSG00000125630.14	ENST00000537335	hsa-miR-4635	112576790	112576796	7mer-m8	112576777	112576797	160	-21.63
CAediting_1229415	chr17_67471547_+	ENSG00000125630.14	ENST00000541869	hsa-miR-548aa	112576899	112576905	7mer-m8	112576882	112576906	140	-8.86
CAediting_86358	chr1_109598906_+	ENSG00000125630.14	ENST00000541869	hsa-miR-197-5p	112576800	112576807	8mer-1a	112576779	112576807	145	-26.04
CAediting_228905	chr2_188297554_+	ENSG00000125630.14	ENST00000541869	hsa-miR-561-3p	112575841	112575846	6mer	112575825	112575847	155	-15.47
CAediting_396018	chr5_1062918_-	ENSG00000125630.14	ENST00000541869	hsa-miR-4635	112576790	112576796	7mer-m8	112576777	112576797	160	-21.63
CAediting_573001	chr7_92204086_-	ENSG00000125630.14	ENST00000333990	hsa-miR-1285-5p	112572650	112572656	7mer-m8	112572637	112572657	142	-16.7
CAediting_228905	chr2_188297554_+	ENSG00000125630.14	ENST00000333990	hsa-miR-561-3p	112575841	112575846	6mer	112575825	112575847	155	-15.47
CAediting_1229415	chr17_67471547_+	ENSG00000125630.14	ENST00000409894	hsa-miR-548aa	112576899	112576905	7mer-m8	112576882	112576906	140	-8.86
CAediting_86358	chr1_109598906_+	ENSG00000125630.14	ENST00000409894	hsa-miR-197-5p	112576800	112576807	8mer-1a	112576779	112576807	145	-26.04
CAediting_228905	chr2_188297554_+	ENSG00000125630.14	ENST00000409894	hsa-miR-561-3p	112575841	112575846	6mer	112575825	112575847	155	-15.47
CAediting_396018	chr5_1062918_-	ENSG00000125630.14	ENST00000409894	hsa-miR-4635	112576790	112576796	7mer-m8	112576777	112576797	160	-21.63
CAediting_573001	chr7_92204086_-	ENSG00000125630.14	ENST00000448770	hsa-miR-1285-5p	112572650	112572656	7mer-m8	112572637	112572657	142	-16.7
CAediting_228905	chr2_188297554_+	ENSG00000125630.14	ENST00000448770	hsa-miR-561-3p	112575841	112575846	6mer	112575825	112575847	155	-15.47
CAediting_228905	chr2_188297554_+	ENSG00000125630.14	ENST00000417433	hsa-miR-561-3p	112575841	112575846	6mer	112575825	112575847	155	-15.47

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_117844	chr1_162342605_+	ENSG00000125630.14	ENST00000537335	hsa-miR-556-3p	112576755	112576761	7mer-m8	112576742	112576762	146	-14.21
CAediting_117844	chr1_162342605_+	ENSG00000125630.14	ENST00000537335	hsa-miR-556-3p	112576270	112576277	8mer-1a	112576256	112576277	144	-7.1
CAediting_117844	chr1_162342605_+	ENSG00000125630.14	ENST00000541869	hsa-miR-556-3p	112576755	112576761	7mer-m8	112576742	112576762	146	-14.21
CAediting_117844	chr1_162342605_+	ENSG00000125630.14	ENST00000541869	hsa-miR-556-3p	112576270	112576277	8mer-1a	112576256	112576277	144	-7.1
CAediting_1229413	chr17_67471544_+	ENSG00000125630.14	ENST00000333990	hsa-miR-548aa	112575074	112575080	7mer-m8	112575057	112575081	140	-6.35
CAediting_117844	chr1_162342605_+	ENSG00000125630.14	ENST00000409894	hsa-miR-556-3p	112576755	112576761	7mer-m8	112576742	112576762	146	-14.21
CAediting_117844	chr1_162342605_+	ENSG00000125630.14	ENST00000409894	hsa-miR-556-3p	112576270	112576277	8mer-1a	112576256	112576277	144	-7.1
CAediting_1229413	chr17_67471544_+	ENSG00000125630.14	ENST00000448770	hsa-miR-548aa	112575074	112575080	7mer-m8	112575057	112575081	140	-6.35

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for POLR1B

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000333990.9	nonsense_mediated_decay
ENST00000409894.6	protein_coding
ENST00000537335.4	protein_coding
ENST00000541869.4	protein_coding
ENST00000498054.1	processed_transcript

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_207743	ENST00000333990.9	chr2_112545875_+	-1355.30	-1350.70	-1356.10
CAediting_207744	ENST00000333990.9	chr2_112545881_+	-1356.00	-1350.70	-1356.10
CAediting_207779	ENST00000409894.6	chr2_112576642_+	-1362.50	-1362.40	-1376.70
CAediting_207780	ENST00000409894.6	chr2_112576645_+	-1362.50	-1362.40	-1376.70
CAediting_207781	ENST00000409894.6	chr2_112576664_+	-1369.00	-1362.40	-1376.70
CAediting_207782	ENST00000409894.6	chr2_112576668_+	-1361.70	-1362.40	-1376.70
CAediting_207783	ENST00000409894.6	chr2_112576690_+	-1362.00	-1362.40	-1376.70
CAediting_207784	ENST00000409894.6	chr2_112576705_+	-1367.50	-1362.40	-1376.70
CAediting_207785	ENST00000409894.6	chr2_112576720_+	-1362.80	-1362.40	-1376.70
CAediting_207786	ENST00000409894.6	chr2_112576731_+	-1362.00	-1362.40	-1376.70
CAediting_207787	ENST00000409894.6	chr2_112576781_+	-1362.40	-1362.40	-1376.70
CAediting_207788	ENST00000409894.6	chr2_112576782_+	-1364.90	-1362.40	-1376.70
CAediting_207789	ENST00000409894.6	chr2_112576784_+	-1361.90	-1362.40	-1376.70
CAediting_207790	ENST00000409894.6	chr2_112576790_+	-1363.30	-1362.40	-1376.70
CAediting_207791	ENST00000409894.6	chr2_112576795_+	-1362.10	-1362.40	-1376.70
CAediting_207792	ENST00000409894.6	chr2_112576800_+	-1361.80	-1362.40	-1376.70
CAediting_207793	ENST00000409894.6	chr2_112576829_+	-1365.60	-1362.40	-1376.70
CAediting_207794	ENST00000409894.6	chr2_112576835_+	-1362.10	-1362.40	-1376.70
CAediting_207795	ENST00000409894.6	chr2_112576837_+	-1362.40	-1362.40	-1376.70
CAediting_207796	ENST00000409894.6	chr2_112576844_+	-1362.50	-1362.40	-1376.70
CAediting_207779	ENST00000537335.4	chr2_112576642_+	-1568.70	-1568.60	-1582.90
CAediting_207780	ENST00000537335.4	chr2_112576645_+	-1568.70	-1568.60	-1582.90
CAediting_207781	ENST00000537335.4	chr2_112576664_+	-1575.20	-1568.60	-1582.90
CAediting_207782	ENST00000537335.4	chr2_112576668_+	-1567.90	-1568.60	-1582.90
CAediting_207783	ENST00000537335.4	chr2_112576690_+	-1568.20	-1568.60	-1582.90
CAediting_207784	ENST00000537335.4	chr2_112576705_+	-1573.70	-1568.60	-1582.90
CAediting_207785	ENST00000537335.4	chr2_112576720_+	-1569.00	-1568.60	-1582.90
CAediting_207786	ENST00000537335.4	chr2_112576731_+	-1568.20	-1568.60	-1582.90
CAediting_207787	ENST00000537335.4	chr2_112576781_+	-1568.60	-1568.60	-1582.90
CAediting_207788	ENST00000537335.4	chr2_112576782_+	-1571.10	-1568.60	-1582.90
CAediting_207789	ENST00000537335.4	chr2_112576784_+	-1568.10	-1568.60	-1582.90
CAediting_207790	ENST00000537335.4	chr2_112576790_+	-1569.50	-1568.60	-1582.90
CAediting_207791	ENST00000537335.4	chr2_112576795_+	-1568.30	-1568.60	-1582.90
CAediting_207792	ENST00000537335.4	chr2_112576800_+	-1568.00	-1568.60	-1582.90
CAediting_207793	ENST00000537335.4	chr2_112576829_+	-1571.80	-1568.60	-1582.90
CAediting_207794	ENST00000537335.4	chr2_112576835_+	-1568.30	-1568.60	-1582.90
CAediting_207795	ENST00000537335.4	chr2_112576837_+	-1568.60	-1568.60	-1582.90
CAediting_207796	ENST00000537335.4	chr2_112576844_+	-1568.70	-1568.60	-1582.90
CAediting_207779	ENST00000541869.4	chr2_112576642_+	-1545.00	-1544.90	-1559.20
CAediting_207780	ENST00000541869.4	chr2_112576645_+	-1545.00	-1544.90	-1559.20
CAediting_207781	ENST00000541869.4	chr2_112576664_+	-1551.50	-1544.90	-1559.20
CAediting_207782	ENST00000541869.4	chr2_112576668_+	-1544.20	-1544.90	-1559.20
CAediting_207783	ENST00000541869.4	chr2_112576690_+	-1544.50	-1544.90	-1559.20
CAediting_207784	ENST00000541869.4	chr2_112576705_+	-1550.00	-1544.90	-1559.20
CAediting_207785	ENST00000541869.4	chr2_112576720_+	-1545.30	-1544.90	-1559.20
CAediting_207786	ENST00000541869.4	chr2_112576731_+	-1544.50	-1544.90	-1559.20
CAediting_207787	ENST00000541869.4	chr2_112576781_+	-1544.90	-1544.90	-1559.20
CAediting_207788	ENST00000541869.4	chr2_112576782_+	-1547.40	-1544.90	-1559.20
CAediting_207789	ENST00000541869.4	chr2_112576784_+	-1544.40	-1544.90	-1559.20
CAediting_207790	ENST00000541869.4	chr2_112576790_+	-1545.80	-1544.90	-1559.20
CAediting_207791	ENST00000541869.4	chr2_112576795_+	-1544.60	-1544.90	-1559.20
CAediting_207792	ENST00000541869.4	chr2_112576800_+	-1544.30	-1544.90	-1559.20
CAediting_207793	ENST00000541869.4	chr2_112576829_+	-1548.10	-1544.90	-1559.20
CAediting_207794	ENST00000541869.4	chr2_112576835_+	-1544.60	-1544.90	-1559.20
CAediting_207795	ENST00000541869.4	chr2_112576837_+	-1544.90	-1544.90	-1559.20
CAediting_207796	ENST00000541869.4	chr2_112576844_+	-1545.00	-1544.90	-1559.20
CAediting_207747	ENST00000498054.1	chr2_112553430_+	-184.40	-185.10	-184.40

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Relation with ADAR for POLR1B

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BLCA	CAediting_207781	chr2_112576664_+	3.72954568493602e-15	0.518468162468823	.	.	.	.
LGG	CAediting_207781	chr2_112576664_+	4.5805487425802e-07	0.2400536450375	.	.	0.000188658357594836	0.178914241917434
BRCA	CAediting_207781	chr2_112576664_+	1.5417665284059e-55	0.493617303254247	.	.	.	.
LIHC	CAediting_207781	chr2_112576664_+	7.85232606512723e-05	0.388120306845381	.	.	.	.
CESC	CAediting_207781	chr2_112576664_+	1.08864037089961e-08	0.444412669618341	.	.	.	.
LUAD	CAediting_207781	chr2_112576664_+	1.55572514184501e-08	0.339902199758605	.	.	.	.
COAD	CAediting_207781	chr2_112576664_+	3.48154462238993e-15	0.490188285208564	.	.	.	.
LUSC	CAediting_207781	chr2_112576664_+	6.75219420211352e-22	0.484017684213826	.	.	.	.
GBM	CAediting_207781	chr2_112576664_+	0.0157355241606735	0.194962124328146	.	.	.	.
PRAD	CAediting_207781	chr2_112576664_+	3.87591884221569e-13	0.388843880947484	.	.	.	.
HNSC	CAediting_207781	chr2_112576664_+	1.81752965515436e-11	0.409892641505052	.	.	.	.
STAD	CAediting_207781	chr2_112576664_+	1.06368083786048e-06	0.31009098708757	.	.	.	.
THCA	CAediting_207781	chr2_112576664_+	7.3750731115495e-19	0.395864520887942	.	.	.	.
KIRC	CAediting_207781	chr2_112576664_+	1.40533294593938e-09	0.287319655757538	.	.	.	.
UCEC	CAediting_207781	chr2_112576664_+	5.85292235848526e-11	0.481524185892646	.	.	.	.
KIRP	CAediting_207781	chr2_112576664_+	6.46281022314824e-06	0.324795642905638	.	.	.	.
ESCA	CAediting_207781	chr2_112576664_+	4.41061743933306e-05	0.332407333103889	.	.	.	.
OV	CAediting_207781	chr2_112576664_+	1.25441696166623e-11	0.378054045029215	.	.	.	.
PAAD	CAediting_207781	chr2_112576664_+	0.00122317774579885	0.359589681458896	.	.	.	.
PCPG	CAediting_207781	chr2_112576664_+	3.00526975085764e-05	0.418362933254899	0.0105993486742337	0.263861659996591	.	.
SKCM	CAediting_207781	chr2_112576664_+	2.02860673406705e-28	0.521306955166084	.	.	.	.
READ	CAediting_207781	chr2_112576664_+	1.39108016001989e-07	0.548438968384863	.	.	.	.
SARC	CAediting_207781	chr2_112576664_+	7.43172822777183e-10	0.530840313228723	.	.	.	.
TGCT	CAediting_207781	chr2_112576664_+	5.10218419386754e-15	0.623203313681652	.	.	.	.
THYM	CAediting_207781	chr2_112576664_+	1.53796764892351e-09	0.615820484705258	.	.	0.000802367830073562	0.369571526657879
BRCA	CAediting_207791	chr2_112576795_+	.	.	.	.	0.0307968970189981	0.213994569447284
BLCA	CAediting_207795	chr2_112576837_+	0.0211664943910635	0.260668963951265	.	.	.	.
LGG	CAediting_207795	chr2_112576837_+	0.00430880915696868	0.253683149619488	5.26380416475341e-05	0.353474369954033	.	.
BRCA	CAediting_207795	chr2_112576837_+	7.33129372385083e-33	0.491113877236236	.	.	.	.
LIHC	CAediting_207795	chr2_112576837_+	0.00510170589761039	0.348671152124124	.	.	.	.
CESC	CAediting_207795	chr2_112576837_+	0.00288877214586053	0.353471338391902	.	.	.	.
LUAD	CAediting_207795	chr2_112576837_+	0.000173219922830719	0.315483971749583	.	.	.	.
LUSC	CAediting_207795	chr2_112576837_+	5.89778617033352e-06	0.392721635235479	.	.	.	.
GBM	CAediting_207795	chr2_112576837_+	0.00584983133429025	0.351759605741024	.	.	.	.
PRAD	CAediting_207795	chr2_112576837_+	0.00257410199526959	0.341009299225043	.	.	.	.
THCA	CAediting_207795	chr2_112576837_+	0.00132691872219569	0.23124587293499	.	.	.	.
KIRC	CAediting_207795	chr2_112576837_+	0.00438025830140363	0.176853857348561	.	.	.	.
UCEC	CAediting_207795	chr2_112576837_+	0.0467047278338213	0.22448959421453	.	.	.	.
ESCA	CAediting_207795	chr2_112576837_+	0.00982620665638276	0.308826551487695	.	.	.	.
OV	CAediting_207795	chr2_112576837_+	0.00134984453965515	0.23844254389586	.	.	.	.
PCPG	CAediting_207795	chr2_112576837_+	0.0218747435536391	0.23501575987931	.	.	.	.
SKCM	CAediting_207795	chr2_112576837_+	1.57029467118551e-05	0.315812075222524	.	.	.	.
TGCT	CAediting_207795	chr2_112576837_+	0.000219786852717914	0.470708270967508	.	.	.	.

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Relation with cancer stages for POLR1B

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_207795	chr2_112576837_+	0.00522644768194095	0.123614639044379
HNSC	clinical_stage	CAediting_207781	chr2_112576664_+	0.0307260819729083	0.138933838912869
KIRP	clinical_stage	CAediting_207781	chr2_112576664_+	0.0159812551995297	0.206276486278513
KIRP	pathologic_stage	CAediting_207781	chr2_112576664_+	8.22636263820488e-05	0.299051457951722
THCA	pathologic_stage	CAediting_207795	chr2_112576837_+	0.0118130689289504	0.184263906897241

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Relation with survival for POLR1B

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for POLR1B

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for POLR1B

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene