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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: ZNF34 (CAeditome ID:80778)

Gene summary for ZNF34

check button Gene summary
Gene informationGene symbol

ZNF34

Gene ID

80778

Gene namezinc finger protein 34
SynonymsKOX32
Cytomap

8q24.3

Type of geneprotein-coding
Descriptionzinc finger protein 34zinc finger protein 34 (KOX 32)zinc finger protein KOX32
Modification date20210518
UniProtAcc

Q8IZ26

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ZNF34

GO:0005654

Zinc finger protein 34

0000052

ZNF34

GO:0005829

Zinc finger protein 34

0000052


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RNA A-to-I events for ZNF34

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000196378.10

check button RNA A-to-I editing events in Cancer.
CAediting_672614(144773424, -), CAediting_672615(144773446, -), CAediting_672616(144780902, -), CAediting_672617(144784663, -), CAediting_672618(144786014, -), CAediting_672619(144786015, -), CAediting_672620(144786052, -), CAediting_672621(144786057, -), CAediting_672622(144786068, -), CAediting_672623(144786074, -), CAediting_672624(144786096, -), CAediting_672625(144786117, -), CAediting_672626(144786123, -), CAediting_672627(144786136, -), CAediting_672628(144786149, -), CAediting_672629(144786181, -), CAediting_672630(144786187, -), CAediting_672631(144786220, -), CAediting_672632(144786223, -), CAediting_672633(144786262, -), CAediting_672634(144786270, -), CAediting_672635(144786280, -), CAediting_672636(144786377, -), CAediting_672637(144786379, -), CAediting_672638(144786391, -), CAediting_672639(144786442, -), CAediting_672640(144786451, -), CAediting_672641(144786490, -), CAediting_672642(144786499, -), CAediting_672643(144786510, -), CAediting_672644(144786512, -), CAediting_672645(144786534, -), CAediting_672646(144786576, -), CAediting_672647(144786587, -), CAediting_672648(144786595, -), CAediting_672649(144786630, -), CAediting_672650(144786632, -),

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RNA editing positional annotations for ZNF34 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_672614chr8_144773424_-exonic
CAediting_672615chr8_144773446_-exonic
CAediting_672616chr8_144780902_-ncRNA_intronic
CAediting_672617chr8_144784663_-ncRNA_intronic
CAediting_672618chr8_144786014_-ncRNA_intronic
CAediting_672619chr8_144786015_-ncRNA_intronic
CAediting_672620chr8_144786052_-ncRNA_intronic
CAediting_672621chr8_144786057_-ncRNA_intronic
CAediting_672622chr8_144786068_-ncRNA_intronic
CAediting_672623chr8_144786074_-ncRNA_intronic
CAediting_672624chr8_144786096_-ncRNA_intronic
CAediting_672625chr8_144786117_-ncRNA_intronic
CAediting_672626chr8_144786123_-ncRNA_intronic
CAediting_672627chr8_144786136_-ncRNA_intronic
CAediting_672628chr8_144786149_-ncRNA_intronic
CAediting_672629chr8_144786181_-ncRNA_intronic
CAediting_672630chr8_144786187_-ncRNA_intronic
CAediting_672631chr8_144786220_-ncRNA_intronic
CAediting_672632chr8_144786223_-ncRNA_intronic
CAediting_672633chr8_144786262_-ncRNA_intronic
CAediting_672634chr8_144786270_-ncRNA_intronic
CAediting_672635chr8_144786280_-ncRNA_intronic
CAediting_672636chr8_144786377_-ncRNA_intronic
CAediting_672637chr8_144786379_-ncRNA_intronic
CAediting_672638chr8_144786391_-ncRNA_intronic
CAediting_672639chr8_144786442_-ncRNA_intronic
CAediting_672640chr8_144786451_-ncRNA_intronic
CAediting_672641chr8_144786490_-ncRNA_intronic
CAediting_672642chr8_144786499_-ncRNA_intronic
CAediting_672643chr8_144786510_-ncRNA_intronic
CAediting_672644chr8_144786512_-ncRNA_intronic
CAediting_672645chr8_144786534_-ncRNA_intronic
CAediting_672646chr8_144786576_-ncRNA_intronic
CAediting_672647chr8_144786587_-ncRNA_intronic
CAediting_672648chr8_144786595_-ncRNA_intronic
CAediting_672649chr8_144786630_-ncRNA_intronic
CAediting_672650chr8_144786632_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_672616chr8_144780902_-SINEAluAluY
CAediting_672617chr8_144784663_-SINEAluAluSg4
CAediting_672618chr8_144786014_-SINEAluAluY
CAediting_672619chr8_144786015_-SINEAluAluY
CAediting_672620chr8_144786052_-SINEAluAluY
CAediting_672621chr8_144786057_-SINEAluAluY
CAediting_672622chr8_144786068_-SINEAluAluY
CAediting_672623chr8_144786074_-SINEAluAluY
CAediting_672624chr8_144786096_-SINEAluAluY
CAediting_672625chr8_144786117_-SINEAluAluY
CAediting_672626chr8_144786123_-SINEAluAluY
CAediting_672627chr8_144786136_-SINEAluAluY
CAediting_672628chr8_144786149_-SINEAluAluY
CAediting_672629chr8_144786181_-SINEAluAluY
CAediting_672630chr8_144786187_-SINEAluAluY
CAediting_672631chr8_144786220_-SINEAluAluY
CAediting_672632chr8_144786223_-SINEAluAluY
CAediting_672633chr8_144786262_-SINEAluAluY
CAediting_672634chr8_144786270_-SINEAluAluY
CAediting_672635chr8_144786280_-SINEAluAluY
CAediting_672636chr8_144786377_-SINEAluAluSx1
CAediting_672637chr8_144786379_-SINEAluAluSx1
CAediting_672638chr8_144786391_-SINEAluAluSx1
CAediting_672639chr8_144786442_-SINEAluAluSx1
CAediting_672640chr8_144786451_-SINEAluAluSx1
CAediting_672641chr8_144786490_-SINEAluAluSx1
CAediting_672642chr8_144786499_-SINEAluAluSx1
CAediting_672643chr8_144786510_-SINEAluAluSx1
CAediting_672644chr8_144786512_-SINEAluAluSx1
CAediting_672645chr8_144786534_-SINEAluAluSx1
CAediting_672646chr8_144786576_-SINEAluAluSx1
CAediting_672647chr8_144786587_-SINEAluAluSx1
CAediting_672648chr8_144786595_-SINEAluAluSx1
CAediting_672649chr8_144786630_-SINEAluAluSx1
CAediting_672650chr8_144786632_-SINEAluAluSx1

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RNA A-to-I editing events in the alternative splicing sites for ZNF34

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000196378.10.ZNF34.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000196378.10.ZNF34.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF34

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZNF34

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for ZNF34

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_604450chr7_133034877_-ENSG00000196378.10ENST00000343459hsa-miR-36541447732341447732407mer-m8144773233144773251140-18.16

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF34

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZNF34

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ZNF34

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ZNF34

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ZNF34

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF34

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource