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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: CEP63 (CAeditome ID:80254) |
Gene summary for CEP63 |
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Gene information | Gene symbol | CEP63 | Gene ID | 80254 |
Gene name | centrosomal protein 63 | |
Synonyms | SCKL6 | |
Cytomap | 3q22.2 | |
Type of gene | protein-coding | |
Description | centrosomal protein of 63 kDacentrosomal protein 63kDacentrosome protein CEP63 | |
Modification date | 20210522 | |
UniProtAcc | Q96MT8 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
CEP63 | GO:0005813 | Centrosomal protein of 63 kDa | 14654843 |
CEP63 | GO:0005813 | Centrosomal protein of 63 kDa | 21399614 |
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RNA A-to-I events for CEP63 |
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CAediting_309962(134553800, +), CAediting_309963(134563478, +), CAediting_309964(134566779, +), CAediting_309965(134574795, +), CAediting_309966(134574847, +), CAediting_309967(134574860, +), |
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RNA editing positional annotations for CEP63 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_309966 | chr3_134574847_+ | nonsynonymous SNV | ENST00000354446.6 | c.A1384G | p.I462V | D | B | N |
CAediting_309966 | chr3_134574847_+ | nonsynonymous SNV | ENST00000514678.1 | c.A541G | p.I181V | D | B | N |
CAediting_309966 | chr3_134574847_+ | nonsynonymous SNV | ENST00000620544.3 | c.A1384G | p.I462V | D | B | N |
CAediting_309967 | chr3_134574860_+ | nonsynonymous SNV | ENST00000354446.6 | c.A1397G | p.Q466R | D | B | N |
CAediting_309967 | chr3_134574860_+ | nonsynonymous SNV | ENST00000514678.1 | c.A554G | p.Q185R | D | B | N |
CAediting_309967 | chr3_134574860_+ | nonsynonymous SNV | ENST00000620544.3 | c.A1397G | p.Q466R | D | B | N |
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CAeditome ID | Position | Variant type |
CAediting_309962 | chr3_134553800_+ | ncRNA_intronic |
CAediting_309963 | chr3_134563478_+ | ncRNA_intronic |
CAediting_309964 | chr3_134566779_+ | ncRNA_intronic |
CAediting_309965 | chr3_134574795_+ | exonic |
CAediting_309966 | chr3_134574847_+ | exonic |
CAediting_309967 | chr3_134574860_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_309963 | chr3_134563478_+ | SINE | Alu | AluSz |
CAediting_309964 | chr3_134566779_+ | LINE | L1 | L1MB7 |
CAediting_309965 | chr3_134574795_+ | SINE | Alu | AluJb |
CAediting_309966 | chr3_134574847_+ | SINE | Alu | AluJb |
CAediting_309967 | chr3_134574860_+ | SINE | Alu | AluJb |
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RNA A-to-I editing events in the alternative splicing sites for CEP63 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CEP63 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for CEP63 |
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The effects of the RNA editing to the miRNA binding sites for CEP63 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for CEP63 |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
CAediting_309963 | ENST00000337090.6 | chr3_134563478_+ | -1515.40 | -1516.10 | -1515.40 |
CAediting_309965 | ENST00000354446.6 | chr3_134574795_+ | -462.10 | -462.20 | -464.60 |
CAediting_309966 | ENST00000354446.6 | chr3_134574847_+ | -462.20 | -462.20 | -464.60 |
CAediting_309967 | ENST00000354446.6 | chr3_134574860_+ | -464.70 | -462.20 | -464.60 |
CAediting_309965 | ENST00000510625.1 | chr3_134574795_+ | -486.30 | -485.20 | -489.00 |
CAediting_309966 | ENST00000510625.1 | chr3_134574847_+ | -485.20 | -485.20 | -489.00 |
CAediting_309967 | ENST00000510625.1 | chr3_134574860_+ | -487.90 | -485.20 | -489.00 |
CAediting_309965 | ENST00000514678.1 | chr3_134574795_+ | -160.40 | -160.10 | -160.30 |
CAediting_309966 | ENST00000514678.1 | chr3_134574847_+ | -160.10 | -160.10 | -160.30 |
CAediting_309967 | ENST00000514678.1 | chr3_134574860_+ | -160.00 | -160.10 | -160.30 |
CAediting_309965 | ENST00000620544.3 | chr3_134574795_+ | -395.90 | -396.50 | -397.40 |
CAediting_309966 | ENST00000620544.3 | chr3_134574847_+ | -396.50 | -396.50 | -397.40 |
CAediting_309967 | ENST00000620544.3 | chr3_134574860_+ | -398.00 | -396.50 | -397.40 |
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Relation with ADAR for CEP63 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for CEP63 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for CEP63 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for CEP63 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for CEP63 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
CEP63 | C3553582 | SECKEL SYNDROME 6 | 3 | GENOMICS_ENGLAND |
CEP63 | C0025958 | Microcephaly | 2 | CTD_human;GENOMICS_ENGLAND |
CEP63 | C0431350 | Primary microcephaly | 1 | GENOMICS_ENGLAND |
CEP63 | C0920296 | Developmental reading disorder | 1 | GENOMICS_ENGLAND |
CEP63 | C1956147 | Microlissencephaly | 1 | CTD_human |
CEP63 | C3853041 | Severe Congenital Microcephaly | 1 | CTD_human |