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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

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Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: TMEM231 (CAeditome ID:79583)

Gene summary for TMEM231

check button Gene summary
Gene informationGene symbol

TMEM231

Gene ID

79583

Gene nametransmembrane protein 231
SynonymsALYE870|JBTS20|MKS11|PRO1886
Cytomap

16q23.1

Type of geneprotein-coding
Descriptiontransmembrane protein 231
Modification date20210518
UniProtAcc

Q9H6L2

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for TMEM231

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000205084.9
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1136058(75536877, -), CAediting_1136059(75536878, -), CAediting_1136060(75536904, -), CAediting_1136061(75536917, -), CAediting_1136062(75536950, -), CAediting_1136063(75536956, -), CAediting_1136064(75536959, -), CAediting_1136065(75536973, -), CAediting_1136066(75536987, -), CAediting_1136067(75536990, -), CAediting_1136068(75537000, -), CAediting_1136069(75537010, -), CAediting_1136070(75537022, -), CAediting_1136071(75537039, -), CAediting_1136072(75537040, -), CAediting_1136073(75537046, -), CAediting_1136074(75537060, -), CAediting_1136075(75537070, -), CAediting_1136076(75537081, -), CAediting_1136077(75537100, -), CAediting_1136078(75537114, -), CAediting_1136079(75537116, -), CAediting_1136080(75537517, -), CAediting_1136081(75537523, -), CAediting_1136082(75537525, -), CAediting_1136083(75537544, -), CAediting_1136084(75537552, -), CAediting_1136085(75537554, -), CAediting_1136086(75537559, -), CAediting_1136087(75537563, -), CAediting_1136088(75537570, -), CAediting_1136089(75537576, -), CAediting_1136090(75537583, -), CAediting_1136091(75537584, -), CAediting_1136092(75537592, -), CAediting_1136093(75537598, -), CAediting_1136094(75537611, -), CAediting_1136095(75537655, -), CAediting_1136096(75537656, -), CAediting_1136097(75537664, -), CAediting_1136098(75537665, -), CAediting_1136099(75537666, -), CAediting_1136100(75537669, -), CAediting_1136101(75537680, -), CAediting_1136102(75537714, -), CAediting_1136103(75537719, -), CAediting_1136104(75537741, -), CAediting_1136105(75537752, -), CAediting_1136106(75537757, -), CAediting_1136107(75537758, -), CAediting_1136108(75538162, -), CAediting_1136109(75538197, -), CAediting_1136110(75538216, -), CAediting_1136111(75538232, -), CAediting_1136112(75538237, -), CAediting_1136113(75538248, -), CAediting_1136114(75538256, -), CAediting_1136115(75538261, -), CAediting_1136116(75538277, -), CAediting_1136117(75538278, -), CAediting_1136118(75538296, -), CAediting_1136119(75538308, -), CAediting_1136120(75541129, -), CAediting_1136121(75541168, -), CAediting_1136122(75543121, -), CAediting_1136123(75543401, -), CAediting_1136124(75543448, -), CAediting_1136125(75545093, -), CAediting_1136126(75545094, -), CAediting_1136127(75545115, -), CAediting_1136128(75545119, -), CAediting_1136129(75545169, -), CAediting_1136130(75545172, -), CAediting_1136131(75545173, -), CAediting_1136132(75545188, -), CAediting_1136133(75545193, -), CAediting_1136134(75545241, -), CAediting_1136135(75545255, -), CAediting_1136136(75546616, -), CAediting_1136137(75548721, -), CAediting_1136138(75550777, -), CAediting_1136139(75550806, -), CAediting_1136140(75550813, -), CAediting_1136141(75550814, -), CAediting_1136142(75550822, -), CAediting_1136143(75550828, -), CAediting_1136144(75550832, -), CAediting_1136145(75550855, -), CAediting_1136146(75550881, -), CAediting_1136147(75551394, -), CAediting_1136148(75553384, -),

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RNA editing positional annotations for TMEM231 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1136058chr16_75536877_-UTR3
CAediting_1136059chr16_75536878_-UTR3
CAediting_1136060chr16_75536904_-UTR3
CAediting_1136061chr16_75536917_-UTR3
CAediting_1136062chr16_75536950_-UTR3
CAediting_1136063chr16_75536956_-UTR3
CAediting_1136064chr16_75536959_-UTR3
CAediting_1136065chr16_75536973_-UTR3
CAediting_1136066chr16_75536987_-UTR3
CAediting_1136067chr16_75536990_-UTR3
CAediting_1136068chr16_75537000_-UTR3
CAediting_1136069chr16_75537010_-UTR3
CAediting_1136070chr16_75537022_-UTR3
CAediting_1136071chr16_75537039_-UTR3
CAediting_1136072chr16_75537040_-UTR3
CAediting_1136073chr16_75537046_-UTR3
CAediting_1136074chr16_75537060_-UTR3
CAediting_1136075chr16_75537070_-UTR3
CAediting_1136076chr16_75537081_-UTR3
CAediting_1136077chr16_75537100_-UTR3
CAediting_1136078chr16_75537114_-UTR3
CAediting_1136079chr16_75537116_-UTR3
CAediting_1136080chr16_75537517_-UTR3
CAediting_1136081chr16_75537523_-UTR3
CAediting_1136082chr16_75537525_-UTR3
CAediting_1136083chr16_75537544_-UTR3
CAediting_1136084chr16_75537552_-UTR3
CAediting_1136085chr16_75537554_-UTR3
CAediting_1136086chr16_75537559_-UTR3
CAediting_1136087chr16_75537563_-UTR3
CAediting_1136088chr16_75537570_-UTR3
CAediting_1136089chr16_75537576_-UTR3
CAediting_1136090chr16_75537583_-UTR3
CAediting_1136091chr16_75537584_-UTR3
CAediting_1136092chr16_75537592_-UTR3
CAediting_1136093chr16_75537598_-UTR3
CAediting_1136094chr16_75537611_-UTR3
CAediting_1136095chr16_75537655_-UTR3
CAediting_1136096chr16_75537656_-UTR3
CAediting_1136097chr16_75537664_-UTR3
CAediting_1136098chr16_75537665_-UTR3
CAediting_1136099chr16_75537666_-UTR3
CAediting_1136100chr16_75537669_-UTR3
CAediting_1136101chr16_75537680_-UTR3
CAediting_1136102chr16_75537714_-UTR3
CAediting_1136103chr16_75537719_-UTR3
CAediting_1136104chr16_75537741_-UTR3
CAediting_1136105chr16_75537752_-UTR3
CAediting_1136106chr16_75537757_-UTR3
CAediting_1136107chr16_75537758_-UTR3
CAediting_1136108chr16_75538162_-UTR3
CAediting_1136109chr16_75538197_-UTR3
CAediting_1136110chr16_75538216_-UTR3
CAediting_1136111chr16_75538232_-UTR3
CAediting_1136112chr16_75538237_-UTR3
CAediting_1136113chr16_75538248_-UTR3
CAediting_1136114chr16_75538256_-UTR3
CAediting_1136115chr16_75538261_-UTR3
CAediting_1136116chr16_75538277_-UTR3
CAediting_1136117chr16_75538278_-UTR3
CAediting_1136118chr16_75538296_-UTR3
CAediting_1136119chr16_75538308_-UTR3
CAediting_1136120chr16_75541129_-ncRNA_intronic
CAediting_1136121chr16_75541168_-ncRNA_intronic
CAediting_1136122chr16_75543121_-ncRNA_intronic
CAediting_1136123chr16_75543401_-ncRNA_intronic
CAediting_1136124chr16_75543448_-ncRNA_intronic
CAediting_1136125chr16_75545093_-ncRNA_intronic
CAediting_1136126chr16_75545094_-ncRNA_intronic
CAediting_1136127chr16_75545115_-ncRNA_intronic
CAediting_1136128chr16_75545119_-ncRNA_intronic
CAediting_1136129chr16_75545169_-ncRNA_intronic
CAediting_1136130chr16_75545172_-ncRNA_intronic
CAediting_1136131chr16_75545173_-ncRNA_intronic
CAediting_1136132chr16_75545188_-ncRNA_intronic
CAediting_1136133chr16_75545193_-ncRNA_intronic
CAediting_1136134chr16_75545241_-ncRNA_intronic
CAediting_1136135chr16_75545255_-ncRNA_intronic
CAediting_1136136chr16_75546616_-ncRNA_intronic
CAediting_1136137chr16_75548721_-ncRNA_intronic
CAediting_1136138chr16_75550777_-ncRNA_intronic
CAediting_1136139chr16_75550806_-ncRNA_intronic
CAediting_1136140chr16_75550813_-ncRNA_intronic
CAediting_1136141chr16_75550814_-ncRNA_intronic
CAediting_1136142chr16_75550822_-ncRNA_intronic
CAediting_1136143chr16_75550828_-ncRNA_intronic
CAediting_1136144chr16_75550832_-ncRNA_intronic
CAediting_1136145chr16_75550855_-ncRNA_intronic
CAediting_1136146chr16_75550881_-ncRNA_intronic
CAediting_1136147chr16_75551394_-ncRNA_intronic
CAediting_1136148chr16_75553384_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1136058chr16_75536877_-SINEAluAluSx1
CAediting_1136059chr16_75536878_-SINEAluAluSx1
CAediting_1136060chr16_75536904_-SINEAluAluSx1
CAediting_1136061chr16_75536917_-SINEAluAluSx1
CAediting_1136062chr16_75536950_-SINEAluAluSx1
CAediting_1136063chr16_75536956_-SINEAluAluSx1
CAediting_1136064chr16_75536959_-SINEAluAluSx1
CAediting_1136065chr16_75536973_-SINEAluAluSx1
CAediting_1136066chr16_75536987_-SINEAluAluSx1
CAediting_1136067chr16_75536990_-SINEAluAluSx1
CAediting_1136068chr16_75537000_-SINEAluAluSx1
CAediting_1136069chr16_75537010_-SINEAluAluSx1
CAediting_1136070chr16_75537022_-SINEAluAluSx1
CAediting_1136071chr16_75537039_-SINEAluAluSx1
CAediting_1136072chr16_75537040_-SINEAluAluSx1
CAediting_1136073chr16_75537046_-SINEAluAluSx1
CAediting_1136074chr16_75537060_-SINEAluAluSx1
CAediting_1136075chr16_75537070_-SINEAluAluSx1
CAediting_1136076chr16_75537081_-SINEAluAluSx1
CAediting_1136077chr16_75537100_-SINEAluAluSx1
CAediting_1136078chr16_75537114_-SINEAluAluSx1
CAediting_1136079chr16_75537116_-SINEAluAluSx1
CAediting_1136080chr16_75537517_-SINEAluAluSc5
CAediting_1136081chr16_75537523_-SINEAluAluSc5
CAediting_1136082chr16_75537525_-SINEAluAluSc5
CAediting_1136083chr16_75537544_-SINEAluAluSc5
CAediting_1136084chr16_75537552_-SINEAluAluSc5
CAediting_1136085chr16_75537554_-SINEAluAluSc5
CAediting_1136086chr16_75537559_-SINEAluAluSc5
CAediting_1136087chr16_75537563_-SINEAluAluSc5
CAediting_1136088chr16_75537570_-SINEAluAluSc5
CAediting_1136089chr16_75537576_-SINEAluAluSc5
CAediting_1136090chr16_75537583_-SINEAluAluSc5
CAediting_1136091chr16_75537584_-SINEAluAluSc5
CAediting_1136092chr16_75537592_-SINEAluAluSc5
CAediting_1136093chr16_75537598_-SINEAluAluSc5
CAediting_1136094chr16_75537611_-SINEAluAluSc5
CAediting_1136095chr16_75537655_-SINEAluAluSc5
CAediting_1136096chr16_75537656_-SINEAluAluSc5
CAediting_1136097chr16_75537664_-SINEAluAluSc5
CAediting_1136098chr16_75537665_-SINEAluAluSc5
CAediting_1136099chr16_75537666_-SINEAluAluSc5
CAediting_1136100chr16_75537669_-SINEAluAluSc5
CAediting_1136101chr16_75537680_-SINEAluAluSc5
CAediting_1136102chr16_75537714_-SINEAluAluSc5
CAediting_1136103chr16_75537719_-SINEAluAluSc5
CAediting_1136104chr16_75537741_-SINEAluAluSc5
CAediting_1136105chr16_75537752_-SINEAluAluSc5
CAediting_1136106chr16_75537757_-SINEAluAluSc5
CAediting_1136107chr16_75537758_-SINEAluAluSc5
CAediting_1136108chr16_75538162_-SINEAluAluJr
CAediting_1136109chr16_75538197_-SINEAluAluJr
CAediting_1136110chr16_75538216_-SINEAluAluJr
CAediting_1136111chr16_75538232_-SINEAluAluJr
CAediting_1136112chr16_75538237_-SINEAluAluJr
CAediting_1136113chr16_75538248_-SINEAluAluJr
CAediting_1136114chr16_75538256_-SINEAluAluJr
CAediting_1136115chr16_75538261_-SINEAluAluJr
CAediting_1136116chr16_75538277_-SINEAluAluJr
CAediting_1136117chr16_75538278_-SINEAluAluJr
CAediting_1136118chr16_75538296_-SINEAluAluJr
CAediting_1136120chr16_75541129_-SINEAluAluJo
CAediting_1136121chr16_75541168_-SINEAluAluJo
CAediting_1136122chr16_75543121_-SINEAluAluJo
CAediting_1136123chr16_75543401_-SINEAluAluSz
CAediting_1136124chr16_75543448_-SINEAluAluSz
CAediting_1136125chr16_75545093_-SINEAluAluSz
CAediting_1136126chr16_75545094_-SINEAluAluSz
CAediting_1136127chr16_75545115_-SINEAluAluSz
CAediting_1136128chr16_75545119_-SINEAluAluSz
CAediting_1136129chr16_75545169_-SINEAluAluSz
CAediting_1136130chr16_75545172_-SINEAluAluSz
CAediting_1136131chr16_75545173_-SINEAluAluSz
CAediting_1136132chr16_75545188_-SINEAluAluSz
CAediting_1136133chr16_75545193_-SINEAluAluSz
CAediting_1136134chr16_75545241_-SINEAluAluSz
CAediting_1136135chr16_75545255_-SINEAluAluSz
CAediting_1136136chr16_75546616_-SINEAluAluSx1
CAediting_1136137chr16_75548721_-SINEAluAluSz
CAediting_1136138chr16_75550777_-SINEAluAluSx1
CAediting_1136139chr16_75550806_-SINEAluAluSx1
CAediting_1136140chr16_75550813_-SINEAluAluSx1
CAediting_1136141chr16_75550814_-SINEAluAluSx1
CAediting_1136142chr16_75550822_-SINEAluAluSx1
CAediting_1136143chr16_75550828_-SINEAluAluSx1
CAediting_1136144chr16_75550832_-SINEAluAluSx1
CAediting_1136145chr16_75550855_-SINEAluAluSx1
CAediting_1136146chr16_75550881_-SINEAluAluSx1
CAediting_1136147chr16_75551394_-SINEAluAluJb
CAediting_1136148chr16_75553384_-SINEAluAluSx3

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RNA A-to-I editing events in the alternative splicing sites for TMEM231

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000205084.9.TMEM231.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000205084.9.TMEM231.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TMEM231

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
GBM.CAediting_1136063.ENSG00000205084.TMEM231.png
Soverview
LGG.CAediting_1136063.ENSG00000205084.TMEM231.png
Soverview
OV.CAediting_1136063.ENSG00000205084.TMEM231.png
Soverview
UCEC.CAediting_1136075.ENSG00000205084.TMEM231.png
Soverview

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Protein coding region RNA A-to-I editings for TMEM231

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for TMEM231

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000562410hsa-miR-367275538271755382788mer-1a7553827175538296155.00-13.91
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000562410hsa-miR-6864-3p75538271755382788mer-1a7553827175538291142.00-10.97
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000568377hsa-miR-367275538271755382788mer-1a7553827175538296155.00-13.91
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000568377hsa-miR-6864-3p75538271755382788mer-1a7553827175538291142.00-10.97
CAediting_1136109chr16_75538197_-ENSG00000205084.9ENST00000562410hsa-miR-4746-3p75538196755382027mer-m87553819575538218144.00-20.83
CAediting_1136109chr16_75538197_-ENSG00000205084.9ENST00000568377hsa-miR-4746-3p75538196755382027mer-m87553819575538218144.00-20.83
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-3136-3p75538234755382407mer-m87553823375538254148.00-16.28
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-6773-5p75538232755382387mer-m87553823175538253153.00-23.04
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-7155-3p75538234755382407mer-m87553823375538254148.00-26.42
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-3136-3p75538234755382407mer-m87553823375538254148.00-16.28
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-6724-5p75538232755382387mer-m87553823175538252145.00-22.57
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-6773-5p75538232755382387mer-m87553823175538253153.00-23.04
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-7155-3p75538234755382407mer-m87553823375538254148.00-26.42
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000562410hsa-miR-361-3p75538260755382656mer7553825975538279141.00-22.62
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000568377hsa-miR-361-3p75538260755382656mer7553825975538279141.00-22.62
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000562410hsa-miR-513a-5p75538277755382837mer-m87553827675538293152.00-17.01
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000562410hsa-miR-513a-5p75538277755382837mer-m87553827675538293152.00-17.01
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000562410hsa-miR-569475538274755382796mer7553827375538293147.00-18.85
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000568377hsa-miR-513a-5p75538277755382837mer-m87553827675538293152.00-17.01
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000568377hsa-miR-513a-5p75538277755382837mer-m87553827675538293152.00-17.01
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000568377hsa-miR-569475538274755382796mer7553827375538293147.00-18.85
CAediting_1136108chr16_75538162_-ENSG00000205084.9ENST00000562410hsa-miR-132475538158755381647mer-m87553815775538184148.00-18.79
CAediting_1136108chr16_75538162_-ENSG00000205084.9ENST00000562410hsa-miR-4524b-3p75538159755381657mer-m87553815875538177156.00-20.03
CAediting_1136108chr16_75538162_-ENSG00000205084.9ENST00000568377hsa-miR-132475538158755381647mer-m87553815775538184148.00-18.79
CAediting_1136108chr16_75538162_-ENSG00000205084.9ENST00000568377hsa-miR-4524b-3p75538159755381657mer-m87553815875538177156.00-20.03

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000562410hsa-miR-10399-5p75538276755382827mer-m87553827575538296148-10.56
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000562410hsa-miR-10399-5p75538276755382827mer-m87553827575538296148-10.56
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000562410hsa-miR-10400-3p75538232755382387mer-m87553823175538252140-20.37
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-10400-3p75538232755382387mer-m87553823175538252140-20.37
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-118475538215755382217mer-m87553821475538232147-18.54
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-118475538215755382217mer-m87553821475538232147-18.54
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-118475538215755382217mer-m87553821475538232147-18.54
CAediting_1136113chr16_75538248_-ENSG00000205084.9ENST00000562410hsa-miR-1260b75538248755382547mer-m87553824775538265153-21.5
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000562410hsa-miR-1343-3p75538229755382357mer-m87553822875538249140-20.74
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000562410hsa-miR-150-5p75538260755382667mer-m87553825975538280140-15.81
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-441875538214755382207mer-m87553821375538229149-23.55
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-443775538232755382398mer-1a7553823275538252146-19.6
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000562410hsa-miR-467475538232755382387mer-m87553823175538251147-22.8
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000562410hsa-miR-467475538232755382387mer-m87553823175538251147-22.8
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-509-3-5p75538214755382207mer-m87553821375538234142-18.95
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-509-5p75538214755382207mer-m87553821375538233144-16.12
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-509-5p75538214755382207mer-m87553821375538233144-16.12
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000562410hsa-miR-518675538272755382787mer-1a7553827275538291141-10.94
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000562410hsa-miR-518675538272755382787mer-1a7553827275538291141-10.94
CAediting_1136108chr16_75538162_-ENSG00000205084.9ENST00000562410hsa-miR-568375538157755381626mer7553815675538181140-16.03
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000562410hsa-miR-6504-3p75538276755382827mer-m87553827575538296149-12.32
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000562410hsa-miR-6504-3p75538276755382827mer-m87553827575538296149-12.32
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000562410hsa-miR-6778-3p75538258755382647mer-m87553825775538277143-13.97
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000562410hsa-miR-6783-3p75538229755382357mer-m87553822875538249151-25.03
CAediting_1136114chr16_75538256_-ENSG00000205084.9ENST00000562410hsa-miR-6878-3p75538255755382628mer-1a7553825575538275142-13.53
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000562410hsa-miR-6878-3p75538255755382628mer-1a7553825575538275142-13.53
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000562410hsa-miR-7156-3p75538216755382227mer-m87553821575538235146-24.39
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000562410hsa-miR-939-3p75538229755382368mer-1a7553822975538251148-23.24
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000568377hsa-miR-10399-5p75538276755382827mer-m87553827575538296148-10.56
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000568377hsa-miR-10399-5p75538276755382827mer-m87553827575538296148-10.56
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000568377hsa-miR-10400-3p75538232755382387mer-m87553823175538252140-20.37
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-10400-3p75538232755382387mer-m87553823175538252140-20.37
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-118475538215755382217mer-m87553821475538232147-18.54
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-118475538215755382217mer-m87553821475538232147-18.54
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-118475538215755382217mer-m87553821475538232147-18.54
CAediting_1136113chr16_75538248_-ENSG00000205084.9ENST00000568377hsa-miR-1260b75538248755382547mer-m87553824775538265153-21.5
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000568377hsa-miR-1343-3p75538229755382357mer-m87553822875538249140-20.74
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000568377hsa-miR-150-5p75538260755382667mer-m87553825975538280140-15.81
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-441875538214755382207mer-m87553821375538229149-23.55
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-443775538232755382398mer-1a7553823275538252146-19.6
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000568377hsa-miR-467475538232755382387mer-m87553823175538251147-22.8
CAediting_1136112chr16_75538237_-ENSG00000205084.9ENST00000568377hsa-miR-467475538232755382387mer-m87553823175538251147-22.8
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-509-3-5p75538214755382207mer-m87553821375538234142-18.95
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-509-5p75538214755382207mer-m87553821375538233144-16.12
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-509-5p75538214755382207mer-m87553821375538233144-16.12
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000568377hsa-miR-518675538272755382787mer-1a7553827275538291141-10.94
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000568377hsa-miR-518675538272755382787mer-1a7553827275538291141-10.94
CAediting_1136108chr16_75538162_-ENSG00000205084.9ENST00000568377hsa-miR-568375538157755381626mer7553815675538181140-16.03
CAediting_1136116chr16_75538277_-ENSG00000205084.9ENST00000568377hsa-miR-6504-3p75538276755382827mer-m87553827575538296149-12.32
CAediting_1136117chr16_75538278_-ENSG00000205084.9ENST00000568377hsa-miR-6504-3p75538276755382827mer-m87553827575538296149-12.32
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000568377hsa-miR-6778-3p75538258755382647mer-m87553825775538277143-13.97
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000568377hsa-miR-6783-3p75538229755382357mer-m87553822875538249151-25.03
CAediting_1136114chr16_75538256_-ENSG00000205084.9ENST00000568377hsa-miR-6878-3p75538255755382628mer-1a7553825575538275142-13.53
CAediting_1136115chr16_75538261_-ENSG00000205084.9ENST00000568377hsa-miR-6878-3p75538255755382628mer-1a7553825575538275142-13.53
CAediting_1136110chr16_75538216_-ENSG00000205084.9ENST00000568377hsa-miR-7156-3p75538216755382227mer-m87553821575538235146-24.39
CAediting_1136111chr16_75538232_-ENSG00000205084.9ENST00000568377hsa-miR-939-3p75538229755382368mer-1a7553822975538251148-23.24

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000205084.9ENST00000562410hsa-miR-624-3p75541362755413687mer-m87554136175541380164-25.98
CAediting_688081chr9_63819627_+ENSG00000205084.9ENST00000562410hsa-miR-4477b75538540755385467mer-m87553853975538561157-14.56
CAediting_688081chr9_63819627_+ENSG00000205084.9ENST00000568377hsa-miR-4477b75538540755385467mer-m87553853975538561157-14.56
CAediting_980496chr14_31014685_-ENSG00000205084.9ENST00000570006hsa-miR-624-3p75541362755413687mer-m87554136175541380164-25.98
CAediting_393chr1_1167164_+ENSG00000205084.9ENST00000615437hsa-miR-200b-3p75555370755553767mer-m87555536975555390151-18.22
CAediting_580943chr7_100356700_+ENSG00000205084.9ENST00000562410hsa-miR-6840-3p75545433755454408mer-1a7554543375545454148-25.64
CAediting_1160181chr17_7017644_-ENSG00000205084.9ENST00000562410hsa-miR-195-3p75538394755384007mer-m87553839375538413142-15.16
CAediting_77128chr1_85133844_+ENSG00000205084.9ENST00000562410hsa-miR-4423-3p75538998755390047mer-m87553899775539017145-18.2
CAediting_414656chr5_72878640_+ENSG00000205084.9ENST00000562410hsa-miR-4804-3p75539661755396688mer-1a7553966175539681145-15.23
CAediting_604450chr7_133034877_-ENSG00000205084.9ENST00000562410hsa-miR-365475538913755389197mer-m87553891275538930145-20.06
CAediting_1160181chr17_7017644_-ENSG00000205084.9ENST00000568377hsa-miR-195-3p75538394755384007mer-m87553839375538413142-15.16
CAediting_77128chr1_85133844_+ENSG00000205084.9ENST00000568377hsa-miR-4423-3p75538998755390047mer-m87553899775539017145-18.2
CAediting_414656chr5_72878640_+ENSG00000205084.9ENST00000568377hsa-miR-4804-3p75539661755396688mer-1a7553966175539681145-15.23
CAediting_604450chr7_133034877_-ENSG00000205084.9ENST00000568377hsa-miR-365475538913755389197mer-m87553891275538930145-20.06

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_604450chr7_133034877_-ENSG00000205084.9ENST00000562410hsa-miR-365475538881755388877mer-m87553888075538897143-16.09
CAediting_604450chr7_133034877_-ENSG00000205084.9ENST00000568377hsa-miR-365475538881755388877mer-m87553888075538897143-16.09

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TMEM231

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for TMEM231

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
THCACAediting_1136063chr16_75536956_-....0.02247301389024310.20403051413293
THCACAediting_1136068chr16_75537000_-0.04830419024539440.280719046188936....

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Relation with cancer stages for TMEM231

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for TMEM231

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for TMEM231

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TMEM231

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
TMEM231C3554235JOUBERT SYNDROME 204GENOMICS_ENGLAND;UNIPROT
TMEM231C0431399Familial aplasia of the vermis2GENOMICS_ENGLAND
TMEM231C3714506Meckel syndrome type 12GENOMICS_ENGLAND
TMEM231C3809352MECKEL SYNDROME, TYPE 112GENOMICS_ENGLAND;UNIPROT
TMEM231C0238198Gastrointestinal Stromal Tumors1CTD_human
TMEM231C0265215Meckel-Gruber syndrome1ORPHANET
TMEM231C0406726Orofaciodigital syndrome 31ORPHANET
TMEM231C1855675Arima syndrome1GENOMICS_ENGLAND;ORPHANET
TMEM231C3179349Gastrointestinal Stromal Sarcoma1CTD_human