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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ZNF343 (CAeditome ID:79175)

Gene summary for ZNF343

check button Gene summary
Gene informationGene symbol

ZNF343

Gene ID

79175

Gene namezinc finger protein 343
SynonymsdJ734P14.5
Cytomap

20p13

Type of geneprotein-coding
Descriptionzinc finger protein 343
Modification date20210518
UniProtAcc

Q6P1L6

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ZNF343

GO:1990837

Zinc finger protein 343

28473536


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RNA A-to-I events for ZNF343

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000088876.10

check button RNA A-to-I editing events in Cancer.
CAediting_1399846(2486582, -), CAediting_1399847(2486599, -), CAediting_1399848(2486601, -), CAediting_1399849(2486618, -), CAediting_1399850(2486626, -), CAediting_1399851(2486642, -), CAediting_1399852(2486644, -), CAediting_1399853(2486654, -), CAediting_1399854(2486666, -), CAediting_1399855(2486668, -), CAediting_1399856(2486680, -), CAediting_1399857(2486683, -), CAediting_1399858(2486703, -), CAediting_1399859(2486706, -), CAediting_1399860(2486719, -), CAediting_1399861(2486727, -), CAediting_1399862(2486733, -), CAediting_1399863(2486740, -), CAediting_1399864(2486759, -), CAediting_1399865(2490634, -), CAediting_1399866(2491919, -), CAediting_1399867(2491930, -), CAediting_1399868(2491956, -), CAediting_1399869(2491959, -), CAediting_1399870(2491965, -), CAediting_1399871(2491992, -), CAediting_1399872(2492018, -), CAediting_1399873(2492021, -), CAediting_1399874(2492032, -), CAediting_1399875(2492033, -), CAediting_1399876(2492048, -), CAediting_1399877(2492072, -), CAediting_1399878(2492081, -), CAediting_1399879(2495778, -), CAediting_1399880(2495864, -), CAediting_1399881(2516319, -), CAediting_1399882(2518125, -), CAediting_1399883(2518126, -), CAediting_1399884(2522843, -),

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RNA editing positional annotations for ZNF343 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_1399876chr20_2492048_-nonsynonymous SNVENST00000358413.5c.A341Gp.K114RD.N
CAediting_1399876chr20_2492048_-nonsynonymous SNVENST00000381253.4c.A341Gp.K114RD.N

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1399846chr20_2486582_-ncRNA_intronic
CAediting_1399847chr20_2486599_-ncRNA_intronic
CAediting_1399848chr20_2486601_-ncRNA_intronic
CAediting_1399849chr20_2486618_-ncRNA_intronic
CAediting_1399850chr20_2486626_-ncRNA_intronic
CAediting_1399851chr20_2486642_-exonic
CAediting_1399852chr20_2486644_-exonic
CAediting_1399853chr20_2486654_-exonic
CAediting_1399854chr20_2486666_-exonic
CAediting_1399855chr20_2486668_-exonic
CAediting_1399856chr20_2486680_-exonic
CAediting_1399857chr20_2486683_-exonic
CAediting_1399858chr20_2486703_-exonic
CAediting_1399859chr20_2486706_-exonic
CAediting_1399860chr20_2486719_-exonic
CAediting_1399861chr20_2486727_-exonic
CAediting_1399862chr20_2486733_-exonic
CAediting_1399863chr20_2486740_-exonic
CAediting_1399864chr20_2486759_-exonic
CAediting_1399865chr20_2490634_-ncRNA_intronic
CAediting_1399866chr20_2491919_-ncRNA_intronic
CAediting_1399867chr20_2491930_-ncRNA_intronic
CAediting_1399868chr20_2491956_-ncRNA_intronic
CAediting_1399869chr20_2491959_-ncRNA_intronic
CAediting_1399870chr20_2491965_-ncRNA_intronic
CAediting_1399871chr20_2491992_-ncRNA_intronic
CAediting_1399872chr20_2492018_-ncRNA_intronic
CAediting_1399873chr20_2492021_-ncRNA_intronic
CAediting_1399874chr20_2492032_-exonic
CAediting_1399875chr20_2492033_-exonic
CAediting_1399876chr20_2492048_-exonic
CAediting_1399877chr20_2492072_-exonic
CAediting_1399878chr20_2492081_-exonic
CAediting_1399879chr20_2495778_-intronic
CAediting_1399880chr20_2495864_-intronic
CAediting_1399881chr20_2516319_-intronic
CAediting_1399882chr20_2518125_-intronic
CAediting_1399883chr20_2518126_-intronic
CAediting_1399884chr20_2522843_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1399846chr20_2486582_-SINEAluAluSp
CAediting_1399847chr20_2486599_-SINEAluAluSp
CAediting_1399848chr20_2486601_-SINEAluAluSp
CAediting_1399849chr20_2486618_-SINEAluAluSp
CAediting_1399850chr20_2486626_-SINEAluAluSp
CAediting_1399851chr20_2486642_-SINEAluAluSp
CAediting_1399852chr20_2486644_-SINEAluAluSp
CAediting_1399853chr20_2486654_-SINEAluAluSp
CAediting_1399854chr20_2486666_-SINEAluAluSp
CAediting_1399855chr20_2486668_-SINEAluAluSp
CAediting_1399856chr20_2486680_-SINEAluAluSp
CAediting_1399857chr20_2486683_-SINEAluAluSp
CAediting_1399858chr20_2486703_-SINEAluAluSp
CAediting_1399859chr20_2486706_-SINEAluAluSp
CAediting_1399860chr20_2486719_-SINEAluAluSp
CAediting_1399861chr20_2486727_-SINEAluAluSp
CAediting_1399862chr20_2486733_-SINEAluAluSp
CAediting_1399863chr20_2486740_-SINEAluAluSp
CAediting_1399864chr20_2486759_-SINEAluAluSp
CAediting_1399865chr20_2490634_-SINEAluAluSq2
CAediting_1399866chr20_2491919_-SINEAluAluSc5
CAediting_1399867chr20_2491930_-SINEAluAluSc5
CAediting_1399868chr20_2491956_-SINEAluAluSc5
CAediting_1399869chr20_2491959_-SINEAluAluSc5
CAediting_1399870chr20_2491965_-SINEAluAluSc5
CAediting_1399871chr20_2491992_-SINEAluAluSc5
CAediting_1399872chr20_2492018_-SINEAluAluSc5
CAediting_1399873chr20_2492021_-SINEAluAluSc5
CAediting_1399874chr20_2492032_-SINEAluAluSc5
CAediting_1399875chr20_2492033_-SINEAluAluSc5
CAediting_1399876chr20_2492048_-SINEAluAluSc5
CAediting_1399877chr20_2492072_-SINEAluAluSc5
CAediting_1399878chr20_2492081_-SINEAluAluSc5
CAediting_1399879chr20_2495778_-SINEAluAluSg
CAediting_1399880chr20_2495864_-SINEAluAluSg
CAediting_1399881chr20_2516319_-SINEAluFLAM_C
CAediting_1399882chr20_2518125_-SINEAluAluSx
CAediting_1399883chr20_2518126_-SINEAluAluSx
CAediting_1399884chr20_2522843_-SINEAluAluJb

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RNA A-to-I editing events in the alternative splicing sites for ZNF343

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000088876.10.ZNF343.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000088876.10.ZNF343.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF343

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZNF343

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ZNF343

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1399869chr20_2491959_-ENSG00000088876.10ENST00000381253hsa-miR-6845-3p249195924919657mer-m824919582491979158.00-24.75
CAediting_1399870chr20_2491965_-ENSG00000088876.10ENST00000381253hsa-miR-4713-5p249195924919657mer-1a24919592491979142.00-34.75
CAediting_1399871chr20_2491992_-ENSG00000088876.10ENST00000381253hsa-miR-513a-5p249199124919977mer-m824919902492007156.00-21.79
CAediting_1399871chr20_2491992_-ENSG00000088876.10ENST00000381253hsa-miR-513a-5p249199124919977mer-m824919902492007156.00-21.79
CAediting_1399871chr20_2491992_-ENSG00000088876.10ENST00000381253hsa-miR-5694249198824919936mer24919872492009145.00-19.57
CAediting_1399867chr20_2491930_-ENSG00000088876.10ENST00000381253hsa-miR-6511b-3p249192524919306mer24919242491946140.00-22.48
CAediting_1399867chr20_2491930_-ENSG00000088876.10ENST00000381253hsa-miR-6511b-3p249192524919306mer24919242491946140.00-22.48
CAediting_1399867chr20_2491930_-ENSG00000088876.10ENST00000381253hsa-miR-6784-3p249192524919306mer24919242491946143.00-26.08
CAediting_1399867chr20_2491930_-ENSG00000088876.10ENST00000381253hsa-miR-6862-3p249192524919306mer24919242491947140.00-32.42
CAediting_1399867chr20_2491930_-ENSG00000088876.10ENST00000381253hsa-miR-6862-3p249192524919306mer24919242491947140.00-32.42

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1399871chr20_2491992_-ENSG00000088876.10ENST00000381253hsa-miR-10399-5p249199024919967mer-m824919892492010144-11.52
CAediting_1399870chr20_2491965_-ENSG00000088876.10ENST00000381253hsa-miR-1976249196024919678mer-1a24919602491978146-20.43
CAediting_1399867chr20_2491930_-ENSG00000088876.10ENST00000381253hsa-miR-4772-3p249192924919357mer-m824919282491950154-17.66
CAediting_1399870chr20_2491965_-ENSG00000088876.10ENST00000381253hsa-miR-6747-3p249196224919698mer-1a24919622491982144-21.04
CAediting_1399871chr20_2491992_-ENSG00000088876.10ENST00000381253hsa-miR-7151-3p249199124919988mer-1a24919912492011140-13.7
CAediting_1399868chr20_2491956_-ENSG00000088876.10ENST00000381253hsa-miR-8062249195424919607mer-m824919532491973141-10.43
CAediting_1399869chr20_2491959_-ENSG00000088876.10ENST00000381253hsa-miR-8062249195424919607mer-m824919532491973141-10.43

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000088876.10ENST00000278772hsa-miR-605-3p248237024823778mer-1a24823702482392142-14.57
CAediting_980496chr14_31014685_-ENSG00000088876.10ENST00000278772hsa-miR-624-3p248306424830707mer-m824830632483083142-19.34
CAediting_688080chr9_63819626_+ENSG00000088876.10ENST00000278772hsa-miR-4477b248201224820187mer-m824820112482035144-12.3
CAediting_688080chr9_63819626_+ENSG00000088876.10ENST00000278772hsa-miR-4477b248235124823577mer-m824823502482373159-15.49
CAediting_748296chr10_51299626_+ENSG00000088876.10ENST00000617391hsa-miR-605-3p248237024823778mer-1a24823702482392142-14.57
CAediting_980496chr14_31014685_-ENSG00000088876.10ENST00000617391hsa-miR-624-3p248306424830707mer-m824830632483083142-19.34
CAediting_688080chr9_63819626_+ENSG00000088876.10ENST00000617391hsa-miR-4477b248201224820187mer-m824820112482035144-12.3
CAediting_688080chr9_63819626_+ENSG00000088876.10ENST00000617391hsa-miR-4477b248235124823577mer-m824823502482373159-15.49
CAediting_748296chr10_51299626_+ENSG00000088876.10ENST00000612935hsa-miR-605-3p248237024823778mer-1a24823702482392142-14.57
CAediting_980496chr14_31014685_-ENSG00000088876.10ENST00000612935hsa-miR-624-3p248306424830707mer-m824830632483083142-19.34
CAediting_688080chr9_63819626_+ENSG00000088876.10ENST00000612935hsa-miR-4477b248201224820187mer-m824820112482035144-12.3
CAediting_688080chr9_63819626_+ENSG00000088876.10ENST00000612935hsa-miR-4477b248235124823577mer-m824823502482373159-15.49
CAediting_1351755chr19_40282625_-ENSG00000088876.10ENST00000278772hsa-miR-641248234024823456mer24823392482365140-18.39
CAediting_414656chr5_72878640_+ENSG00000088876.10ENST00000278772hsa-miR-4804-3p248310524831117mer-m824831042483124147-14.3
CAediting_1351755chr19_40282625_-ENSG00000088876.10ENST00000617391hsa-miR-641248234024823456mer24823392482365140-18.39
CAediting_414656chr5_72878640_+ENSG00000088876.10ENST00000617391hsa-miR-4804-3p248310524831117mer-m824831042483124147-14.3
CAediting_1351755chr19_40282625_-ENSG00000088876.10ENST00000612935hsa-miR-641248234024823456mer24823392482365140-18.39
CAediting_414656chr5_72878640_+ENSG00000088876.10ENST00000612935hsa-miR-4804-3p248310524831117mer-m824831042483124147-14.3

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1351755chr19_40282625_-ENSG00000088876.10ENST00000278772hsa-miR-641248193724819437mer-m824819362481960148-18.07
CAediting_1351755chr19_40282625_-ENSG00000088876.10ENST00000617391hsa-miR-641248193724819437mer-m824819362481960148-18.07
CAediting_1351755chr19_40282625_-ENSG00000088876.10ENST00000612935hsa-miR-641248193724819437mer-m824819362481960148-18.07

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF343

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZNF343

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ZNF343

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ZNF343

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ZNF343

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF343

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource