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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: MLPH (CAeditome ID:79083)

Gene summary for MLPH

check button Gene summary
Gene informationGene symbol

MLPH

Gene ID

79083

Gene namemelanophilin
SynonymsSLAC2-A
Cytomap

2q37.3

Type of geneprotein-coding
Descriptionmelanophilinexophilin-3slp homolog lacking C2 domains asynaptotagmin-like protein 2a
Modification date20210518
UniProtAcc

Q9BV36

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
MLPH

GO:0030425

Melanophilin

15357836

MLPH

GO:0048471

Melanophilin

15357836


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RNA A-to-I events for MLPH

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000115648.12
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_250923(237499862, +), CAediting_250924(237499874, +), CAediting_250925(237499884, +), CAediting_250926(237499886, +), CAediting_250927(237499906, +), CAediting_250928(237499968, +), CAediting_250929(237499980, +), CAediting_250930(237499981, +), CAediting_250931(237499998, +), CAediting_250932(237500020, +), CAediting_250933(237501555, +), CAediting_250934(237501563, +), CAediting_250935(237501565, +), CAediting_250936(237501595, +), CAediting_250937(237501597, +), CAediting_250938(237501617, +), CAediting_250939(237501618, +), CAediting_250940(237501645, +), CAediting_250941(237501728, +), CAediting_250942(237501729, +), CAediting_250943(237501755, +), CAediting_250944(237501756, +), CAediting_250945(237501759, +), CAediting_250946(237502841, +), CAediting_250947(237502967, +), CAediting_250948(237502972, +), CAediting_250949(237503052, +), CAediting_250950(237503060, +), CAediting_250951(237503076, +), CAediting_250952(237507125, +), CAediting_250953(237507192, +), CAediting_250954(237507196, +), CAediting_250955(237507247, +), CAediting_250956(237507281, +), CAediting_250957(237507287, +), CAediting_250958(237507319, +), CAediting_250959(237507329, +), CAediting_250960(237548777, +), CAediting_250961(237548786, +), CAediting_250962(237548798, +), CAediting_250963(237550569, +), CAediting_250964(237550571, +), CAediting_250965(237550573, +), CAediting_250966(237550581, +), CAediting_250967(237550605, +), CAediting_250968(237550619, +), CAediting_250969(237550649, +), CAediting_250970(237550650, +), CAediting_250971(237550654, +), CAediting_250972(237550689, +), CAediting_250973(237550691, +), CAediting_250974(237550716, +), CAediting_250975(237550729, +), CAediting_250976(237550732, +), CAediting_250977(237550746, +), CAediting_250978(237550749, +), CAediting_250979(237550758, +), CAediting_250980(237550771, +), CAediting_250981(237550778, +), CAediting_250982(237550783, +), CAediting_250983(237550809, +), CAediting_250984(237550810, +), CAediting_250985(237550811, +), CAediting_250986(237550823, +), CAediting_250987(237550825, +), CAediting_250988(237551700, +), CAediting_250989(237551704, +), CAediting_250990(237551716, +), CAediting_250991(237551722, +), CAediting_250992(237551723, +), CAediting_250993(237551728, +), CAediting_250994(237551739, +), CAediting_250995(237551745, +), CAediting_250996(237551763, +), CAediting_250997(237551764, +), CAediting_250998(237551782, +), CAediting_250999(237551791, +), CAediting_251000(237551792, +), CAediting_251001(237551794, +), CAediting_251002(237551802, +), CAediting_251003(237551807, +), CAediting_251004(237551813, +), CAediting_251005(237551816, +), CAediting_251006(237551817, +), CAediting_251007(237551818, +), CAediting_251008(237551819, +), CAediting_251009(237551820, +), CAediting_251010(237551823, +), CAediting_251011(237551829, +), CAediting_251012(237551832, +), CAediting_251013(237551851, +), CAediting_251014(237551858, +), CAediting_251015(237551864, +), CAediting_251016(237551868, +), CAediting_251017(237551875, +), CAediting_251018(237551881, +), CAediting_251019(237551885, +), CAediting_251020(237551888, +), CAediting_251021(237551894, +), CAediting_251022(237551900, +), CAediting_251023(237551905, +), CAediting_251024(237551909, +), CAediting_251025(237551911, +), CAediting_251026(237551922, +), CAediting_251027(237551927, +), CAediting_251028(237551928, +), CAediting_251029(237551940, +), CAediting_251030(237551965, +), CAediting_251031(237551995, +), CAediting_251032(237554996, +), CAediting_251033(237555007, +), CAediting_251034(237555011, +), CAediting_251035(237555013, +), CAediting_251036(237555014, +), CAediting_251037(237555028, +), CAediting_251038(237555030, +), CAediting_251039(237555035, +), CAediting_251040(237555036, +), CAediting_251041(237555054, +), CAediting_251042(237555081, +), CAediting_251043(237555082, +), CAediting_251044(237555086, +), CAediting_251045(237555092, +), CAediting_251046(237555131, +), CAediting_251047(237555152, +), CAediting_251048(237555170, +), CAediting_251049(237555179, +), CAediting_251050(237555192, +), CAediting_251051(237555218, +),

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RNA editing positional annotations for MLPH using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_250923chr2_237499862_+ncRNA_intronic
CAediting_250924chr2_237499874_+ncRNA_intronic
CAediting_250925chr2_237499884_+ncRNA_intronic
CAediting_250926chr2_237499886_+ncRNA_intronic
CAediting_250927chr2_237499906_+ncRNA_intronic
CAediting_250928chr2_237499968_+ncRNA_intronic
CAediting_250929chr2_237499980_+ncRNA_intronic
CAediting_250930chr2_237499981_+ncRNA_intronic
CAediting_250931chr2_237499998_+ncRNA_intronic
CAediting_250932chr2_237500020_+ncRNA_intronic
CAediting_250933chr2_237501555_+ncRNA_intronic
CAediting_250934chr2_237501563_+ncRNA_intronic
CAediting_250935chr2_237501565_+ncRNA_intronic
CAediting_250936chr2_237501595_+ncRNA_intronic
CAediting_250937chr2_237501597_+ncRNA_intronic
CAediting_250938chr2_237501617_+ncRNA_intronic
CAediting_250939chr2_237501618_+ncRNA_intronic
CAediting_250940chr2_237501645_+ncRNA_intronic
CAediting_250941chr2_237501728_+ncRNA_intronic
CAediting_250942chr2_237501729_+ncRNA_intronic
CAediting_250943chr2_237501755_+ncRNA_intronic
CAediting_250944chr2_237501756_+ncRNA_intronic
CAediting_250945chr2_237501759_+ncRNA_intronic
CAediting_250946chr2_237502841_+ncRNA_intronic
CAediting_250947chr2_237502967_+ncRNA_intronic
CAediting_250948chr2_237502972_+ncRNA_intronic
CAediting_250949chr2_237503052_+ncRNA_intronic
CAediting_250950chr2_237503060_+ncRNA_intronic
CAediting_250951chr2_237503076_+ncRNA_intronic
CAediting_250952chr2_237507125_+ncRNA_intronic
CAediting_250953chr2_237507192_+ncRNA_intronic
CAediting_250954chr2_237507196_+ncRNA_intronic
CAediting_250955chr2_237507247_+ncRNA_splicing
CAediting_250956chr2_237507281_+ncRNA_exonic
CAediting_250957chr2_237507287_+ncRNA_exonic
CAediting_250958chr2_237507319_+ncRNA_exonic
CAediting_250959chr2_237507329_+ncRNA_exonic
CAediting_250960chr2_237548777_+ncRNA_intronic
CAediting_250961chr2_237548786_+ncRNA_intronic
CAediting_250962chr2_237548798_+ncRNA_intronic
CAediting_250963chr2_237550569_+ncRNA_intronic
CAediting_250964chr2_237550571_+ncRNA_intronic
CAediting_250965chr2_237550573_+ncRNA_intronic
CAediting_250966chr2_237550581_+ncRNA_intronic
CAediting_250967chr2_237550605_+ncRNA_intronic
CAediting_250968chr2_237550619_+ncRNA_intronic
CAediting_250969chr2_237550649_+ncRNA_intronic
CAediting_250970chr2_237550650_+ncRNA_intronic
CAediting_250971chr2_237550654_+ncRNA_intronic
CAediting_250972chr2_237550689_+ncRNA_intronic
CAediting_250973chr2_237550691_+ncRNA_intronic
CAediting_250974chr2_237550716_+ncRNA_intronic
CAediting_250975chr2_237550729_+ncRNA_intronic
CAediting_250976chr2_237550732_+ncRNA_intronic
CAediting_250977chr2_237550746_+ncRNA_intronic
CAediting_250978chr2_237550749_+ncRNA_intronic
CAediting_250979chr2_237550758_+ncRNA_intronic
CAediting_250980chr2_237550771_+ncRNA_intronic
CAediting_250981chr2_237550778_+ncRNA_intronic
CAediting_250982chr2_237550783_+ncRNA_intronic
CAediting_250983chr2_237550809_+ncRNA_intronic
CAediting_250984chr2_237550810_+ncRNA_intronic
CAediting_250985chr2_237550811_+ncRNA_intronic
CAediting_250986chr2_237550823_+ncRNA_intronic
CAediting_250987chr2_237550825_+ncRNA_intronic
CAediting_250988chr2_237551700_+ncRNA_intronic
CAediting_250989chr2_237551704_+ncRNA_intronic
CAediting_250990chr2_237551716_+ncRNA_intronic
CAediting_250991chr2_237551722_+ncRNA_intronic
CAediting_250992chr2_237551723_+ncRNA_intronic
CAediting_250993chr2_237551728_+ncRNA_intronic
CAediting_250994chr2_237551739_+ncRNA_intronic
CAediting_250995chr2_237551745_+ncRNA_intronic
CAediting_250996chr2_237551763_+ncRNA_intronic
CAediting_250997chr2_237551764_+ncRNA_intronic
CAediting_250998chr2_237551782_+ncRNA_intronic
CAediting_250999chr2_237551791_+ncRNA_intronic
CAediting_251000chr2_237551792_+ncRNA_intronic
CAediting_251001chr2_237551794_+ncRNA_intronic
CAediting_251002chr2_237551802_+ncRNA_intronic
CAediting_251003chr2_237551807_+ncRNA_intronic
CAediting_251004chr2_237551813_+ncRNA_intronic
CAediting_251005chr2_237551816_+ncRNA_intronic
CAediting_251006chr2_237551817_+ncRNA_intronic
CAediting_251007chr2_237551818_+ncRNA_intronic
CAediting_251008chr2_237551819_+ncRNA_intronic
CAediting_251009chr2_237551820_+ncRNA_intronic
CAediting_251010chr2_237551823_+ncRNA_intronic
CAediting_251011chr2_237551829_+ncRNA_intronic
CAediting_251012chr2_237551832_+ncRNA_intronic
CAediting_251013chr2_237551851_+ncRNA_intronic
CAediting_251014chr2_237551858_+ncRNA_intronic
CAediting_251015chr2_237551864_+ncRNA_intronic
CAediting_251016chr2_237551868_+ncRNA_intronic
CAediting_251017chr2_237551875_+ncRNA_intronic
CAediting_251018chr2_237551881_+ncRNA_intronic
CAediting_251019chr2_237551885_+ncRNA_intronic
CAediting_251020chr2_237551888_+ncRNA_intronic
CAediting_251021chr2_237551894_+ncRNA_intronic
CAediting_251022chr2_237551900_+ncRNA_intronic
CAediting_251023chr2_237551905_+ncRNA_intronic
CAediting_251024chr2_237551909_+ncRNA_intronic
CAediting_251025chr2_237551911_+ncRNA_intronic
CAediting_251026chr2_237551922_+ncRNA_intronic
CAediting_251027chr2_237551927_+ncRNA_intronic
CAediting_251028chr2_237551928_+ncRNA_intronic
CAediting_251029chr2_237551940_+ncRNA_intronic
CAediting_251030chr2_237551965_+ncRNA_intronic
CAediting_251031chr2_237551995_+ncRNA_intronic
CAediting_251032chr2_237554996_+UTR3
CAediting_251033chr2_237555007_+UTR3
CAediting_251034chr2_237555011_+UTR3
CAediting_251035chr2_237555013_+UTR3
CAediting_251036chr2_237555014_+UTR3
CAediting_251037chr2_237555028_+UTR3
CAediting_251038chr2_237555030_+UTR3
CAediting_251039chr2_237555035_+UTR3
CAediting_251040chr2_237555036_+UTR3
CAediting_251041chr2_237555054_+UTR3
CAediting_251042chr2_237555081_+UTR3
CAediting_251043chr2_237555082_+UTR3
CAediting_251044chr2_237555086_+UTR3
CAediting_251045chr2_237555092_+UTR3
CAediting_251046chr2_237555131_+UTR3
CAediting_251047chr2_237555152_+UTR3
CAediting_251048chr2_237555170_+UTR3
CAediting_251049chr2_237555179_+UTR3
CAediting_251050chr2_237555192_+UTR3
CAediting_251051chr2_237555218_+UTR3

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_250923chr2_237499862_+SINEAluAluJb
CAediting_250924chr2_237499874_+SINEAluAluJb
CAediting_250925chr2_237499884_+SINEAluAluJb
CAediting_250926chr2_237499886_+SINEAluAluJb
CAediting_250927chr2_237499906_+SINEAluAluJb
CAediting_250928chr2_237499968_+SINEAluAluJb
CAediting_250929chr2_237499980_+SINEAluAluJb
CAediting_250930chr2_237499981_+SINEAluAluJb
CAediting_250932chr2_237500020_+SINEAluFLAM_C
CAediting_250933chr2_237501555_+SINEAluAluSx1
CAediting_250934chr2_237501563_+SINEAluAluSx1
CAediting_250935chr2_237501565_+SINEAluAluSx1
CAediting_250936chr2_237501595_+SINEAluAluSx1
CAediting_250937chr2_237501597_+SINEAluAluSx1
CAediting_250938chr2_237501617_+SINEAluAluSx1
CAediting_250939chr2_237501618_+SINEAluAluSx1
CAediting_250940chr2_237501645_+SINEAluAluSx1
CAediting_250941chr2_237501728_+SINEAluAluSx1
CAediting_250942chr2_237501729_+SINEAluAluSx1
CAediting_250943chr2_237501755_+SINEAluAluSx1
CAediting_250944chr2_237501756_+SINEAluAluSx1
CAediting_250945chr2_237501759_+SINEAluAluSx1
CAediting_250946chr2_237502841_+SINEAluAluSx1
CAediting_250947chr2_237502967_+SINEAluAluSx1
CAediting_250948chr2_237502972_+SINEAluAluSx1
CAediting_250949chr2_237503052_+SINEAluAluSx1
CAediting_250950chr2_237503060_+SINEAluAluSx1
CAediting_250951chr2_237503076_+SINEAluAluSx1
CAediting_250952chr2_237507125_+SINEAluAluSz
CAediting_250953chr2_237507192_+SINEAluAluSz
CAediting_250954chr2_237507196_+SINEAluAluSz
CAediting_250955chr2_237507247_+SINEAluAluSz
CAediting_250956chr2_237507281_+SINEAluAluSz
CAediting_250957chr2_237507287_+SINEAluAluSz
CAediting_250958chr2_237507319_+SINEAluAluSz
CAediting_250959chr2_237507329_+SINEAluAluSz
CAediting_250960chr2_237548777_+SINEAluAluY
CAediting_250961chr2_237548786_+SINEAluAluY
CAediting_250962chr2_237548798_+SINEAluAluY
CAediting_250963chr2_237550569_+SINEAluAluSx1
CAediting_250964chr2_237550571_+SINEAluAluSx1
CAediting_250965chr2_237550573_+SINEAluAluSx1
CAediting_250966chr2_237550581_+SINEAluAluSx1
CAediting_250967chr2_237550605_+SINEAluAluSx1
CAediting_250968chr2_237550619_+SINEAluAluSx1
CAediting_250969chr2_237550649_+SINEAluAluSx1
CAediting_250970chr2_237550650_+SINEAluAluSx1
CAediting_250971chr2_237550654_+SINEAluAluSx1
CAediting_250972chr2_237550689_+SINEAluAluSx1
CAediting_250973chr2_237550691_+SINEAluAluSx1
CAediting_250974chr2_237550716_+SINEAluAluSx1
CAediting_250975chr2_237550729_+SINEAluAluSx1
CAediting_250976chr2_237550732_+SINEAluAluSx1
CAediting_250977chr2_237550746_+SINEAluAluSx1
CAediting_250978chr2_237550749_+SINEAluAluSx1
CAediting_250979chr2_237550758_+SINEAluAluSx1
CAediting_250980chr2_237550771_+SINEAluAluSx1
CAediting_250981chr2_237550778_+SINEAluAluSx1
CAediting_250982chr2_237550783_+SINEAluAluSx1
CAediting_250983chr2_237550809_+SINEAluAluSx1
CAediting_250984chr2_237550810_+SINEAluAluSx1
CAediting_250985chr2_237550811_+SINEAluAluSx1
CAediting_250986chr2_237550823_+SINEAluAluSx1
CAediting_250987chr2_237550825_+SINEAluAluSx1
CAediting_250988chr2_237551700_+SINEAluAluSz
CAediting_250989chr2_237551704_+SINEAluAluSz
CAediting_250990chr2_237551716_+SINEAluAluSz
CAediting_250991chr2_237551722_+SINEAluAluSz
CAediting_250992chr2_237551723_+SINEAluAluSz
CAediting_250993chr2_237551728_+SINEAluAluSz
CAediting_250994chr2_237551739_+SINEAluAluSz
CAediting_250995chr2_237551745_+SINEAluAluSz
CAediting_250996chr2_237551763_+SINEAluAluSz
CAediting_250997chr2_237551764_+SINEAluAluSz
CAediting_250998chr2_237551782_+SINEAluAluSz
CAediting_250999chr2_237551791_+SINEAluAluSz
CAediting_251000chr2_237551792_+SINEAluAluSz
CAediting_251001chr2_237551794_+SINEAluAluSz
CAediting_251002chr2_237551802_+SINEAluAluSz
CAediting_251003chr2_237551807_+SINEAluAluSz
CAediting_251004chr2_237551813_+SINEAluAluSz
CAediting_251005chr2_237551816_+SINEAluAluSz
CAediting_251006chr2_237551817_+SINEAluAluSz
CAediting_251007chr2_237551818_+SINEAluAluSz
CAediting_251008chr2_237551819_+SINEAluAluSz
CAediting_251009chr2_237551820_+SINEAluAluSz
CAediting_251010chr2_237551823_+SINEAluAluSz
CAediting_251011chr2_237551829_+SINEAluAluSz
CAediting_251012chr2_237551832_+SINEAluAluSz
CAediting_251013chr2_237551851_+SINEAluAluSz
CAediting_251014chr2_237551858_+SINEAluAluSz
CAediting_251015chr2_237551864_+SINEAluAluSz
CAediting_251016chr2_237551868_+SINEAluAluSz
CAediting_251017chr2_237551875_+SINEAluAluSz
CAediting_251018chr2_237551881_+SINEAluAluSz
CAediting_251019chr2_237551885_+SINEAluAluSz
CAediting_251020chr2_237551888_+SINEAluAluSz
CAediting_251021chr2_237551894_+SINEAluAluSz
CAediting_251022chr2_237551900_+SINEAluAluSz
CAediting_251023chr2_237551905_+SINEAluAluSz
CAediting_251024chr2_237551909_+SINEAluAluSz
CAediting_251025chr2_237551911_+SINEAluAluSz
CAediting_251026chr2_237551922_+SINEAluAluSz
CAediting_251027chr2_237551927_+SINEAluAluSz
CAediting_251028chr2_237551928_+SINEAluAluSz
CAediting_251029chr2_237551940_+SINEAluAluSz
CAediting_251030chr2_237551965_+SINEAluAluSz
CAediting_251031chr2_237551995_+SINEAluAluSz
CAediting_251032chr2_237554996_+SINEAluAluJr
CAediting_251033chr2_237555007_+SINEAluAluJr
CAediting_251034chr2_237555011_+SINEAluAluJr
CAediting_251035chr2_237555013_+SINEAluAluJr
CAediting_251036chr2_237555014_+SINEAluAluJr
CAediting_251037chr2_237555028_+SINEAluAluJr
CAediting_251038chr2_237555030_+SINEAluAluJr
CAediting_251039chr2_237555035_+SINEAluAluJr
CAediting_251040chr2_237555036_+SINEAluAluJr
CAediting_251041chr2_237555054_+SINEAluAluJr
CAediting_251042chr2_237555081_+SINEAluAluJr
CAediting_251043chr2_237555082_+SINEAluAluJr
CAediting_251044chr2_237555086_+SINEAluAluJr
CAediting_251045chr2_237555092_+SINEAluAluJr
CAediting_251046chr2_237555131_+SINEAluAluJr
CAediting_251047chr2_237555152_+SINEAluAluJr
CAediting_251048chr2_237555170_+SINEAluAluJr
CAediting_251049chr2_237555179_+SINEAluAluJr
CAediting_251050chr2_237555192_+SINEAluAluJr
CAediting_251051chr2_237555218_+SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for MLPH

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_250955chr2_237507247_+237507228:2375072503SS0+1iGGCTAATTTTTGCATTTTTAGTA-8.46GGCTAATTTTTGCATTTTTGGTA0.29

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000115648.12.MLPH.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000115648.12.MLPH.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MLPH

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MLPH

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for MLPH

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1229415chr17_67471547_+ENSG00000115648.12ENST00000410032hsa-miR-548aa2375539332375539397mer-m8237553916237553940141-7.43
CAediting_1229415chr17_67471547_+ENSG00000115648.12ENST00000338530hsa-miR-548aa2375539332375539397mer-m8237553916237553940141-7.43
CAediting_1229415chr17_67471547_+ENSG00000115648.12ENST00000409373hsa-miR-548aa2375539332375539397mer-m8237553916237553940141-7.43
CAediting_1229415chr17_67471547_+ENSG00000115648.12ENST00000437893hsa-miR-548aa2375539332375539397mer-m8237553916237553940141-7.43
CAediting_1229415chr17_67471547_+ENSG00000115648.12ENST00000434770hsa-miR-548aa2375539332375539397mer-m8237553916237553940141-7.43

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MLPH

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000264605.6protein_codingSoverviewSoverview
ENST00000477222.4processed_transcriptSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_251032ENST00000264605.6chr2_237554996_+-1434.40-1432.50-1453.00
CAediting_251033ENST00000264605.6chr2_237555007_+-1435.80-1432.50-1453.00
CAediting_251034ENST00000264605.6chr2_237555011_+-1432.30-1432.50-1453.00
CAediting_251035ENST00000264605.6chr2_237555013_+-1431.60-1432.50-1453.00
CAediting_251036ENST00000264605.6chr2_237555014_+-1432.80-1432.50-1453.00
CAediting_251037ENST00000264605.6chr2_237555028_+-1435.80-1432.50-1453.00
CAediting_251038ENST00000264605.6chr2_237555030_+-1437.50-1432.50-1453.00
CAediting_251039ENST00000264605.6chr2_237555035_+-1436.10-1432.50-1453.00
CAediting_251040ENST00000264605.6chr2_237555036_+-1432.50-1432.50-1453.00
CAediting_251041ENST00000264605.6chr2_237555054_+-1434.60-1432.50-1453.00
CAediting_251042ENST00000264605.6chr2_237555081_+-1433.80-1432.50-1453.00
CAediting_251043ENST00000264605.6chr2_237555082_+-1433.00-1432.50-1453.00
CAediting_251044ENST00000264605.6chr2_237555086_+-1432.20-1432.50-1453.00
CAediting_251045ENST00000264605.6chr2_237555092_+-1432.10-1432.50-1453.00
CAediting_251046ENST00000264605.6chr2_237555131_+-1434.00-1432.50-1453.00
CAediting_251047ENST00000264605.6chr2_237555152_+-1431.40-1432.50-1453.00
CAediting_251048ENST00000264605.6chr2_237555170_+-1432.20-1432.50-1453.00
CAediting_251049ENST00000264605.6chr2_237555179_+-1431.70-1432.50-1453.00
CAediting_251050ENST00000264605.6chr2_237555192_+-1432.10-1432.50-1453.00
CAediting_251051ENST00000264605.6chr2_237555218_+-1432.50-1432.50-1453.00
CAediting_250956ENST00000477222.4chr2_237507281_+-214.90-211.30-215.70
CAediting_250957ENST00000477222.4chr2_237507287_+-211.30-211.30-215.70
CAediting_250958ENST00000477222.4chr2_237507319_+-213.20-211.30-215.70
CAediting_250959ENST00000477222.4chr2_237507329_+-211.60-211.30-215.70

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Relation with ADAR for MLPH

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BRCACAediting_250990chr2_237551716_+0.009122598348411910.155018741876561....

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Relation with cancer stages for MLPH

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BRCApathologic_stageCAediting_250964chr2_237550571_+0.0314421622538685-0.252075215895115

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Relation with survival for MLPH

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
SKCMCAediting_250988chr2_237551700_+0.0007828002462271220.006021090.0178614

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RelatedDrugs for MLPH

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MLPH

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
MLPHC1836573GRISCELLI SYNDROME, TYPE 31CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT