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Editing gene: ZNF24 (CAeditome ID:7572)

Gene summary for ZNF24

Gene summary

Gene information	Gene symbol	ZNF24
	Gene ID	7572
	Gene name	zinc finger protein 24
	Synonyms	KOX17\|RSG-A\|ZNF191\|ZSCAN3\|Zfp191
	Cytomap	18q12.2
	Type of gene	protein-coding
	Description	zinc finger protein 24retinoic acid suppression protein Azinc finger and SCAN domain-containing protein 3zinc finger protein 191zinc finger protein 24 (KOX 17)zinc finger protein KOX17
	Modification date	20210518
	UniProtAcc	P17028
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
ZNF24	GO:0001228	Zinc finger protein 24	11532988
ZNF24	GO:0043565	Zinc finger protein 24	11532988
ZNF24	GO:0045892	Zinc finger protein 24	10585455
ZNF24	GO:0045892	Zinc finger protein 24	12801647
ZNF24	GO:0045944	Zinc finger protein 24	11532988
ZNF24	GO:0005654	Zinc finger protein 24	0000052

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RNA A-to-I events for ZNF24

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000172466.14

RNA A-to-I editing events in Cancer.

CAediting_1261003(35337351, -), CAediting_1261004(35337386, -), CAediting_1261005(35337397, -), CAediting_1261006(35337406, -),

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RNA editing positional annotations for ZNF24 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_1261003	chr18_35337351_-	nonsynonymous SNV	ENST00000261332.9	c.A988G	p.T330A	D	B	D
CAediting_1261003	chr18_35337351_-	nonsynonymous SNV	ENST00000399061.3	c.A988G	p.T330A	D	B	D
CAediting_1261004	chr18_35337386_-	nonsynonymous SNV	ENST00000261332.9	c.A953G	p.Q318R	D	B	D
CAediting_1261004	chr18_35337386_-	nonsynonymous SNV	ENST00000399061.3	c.A953G	p.Q318R	D	B	D

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1261003	chr18_35337351_-	exonic
CAediting_1261004	chr18_35337386_-	exonic
CAediting_1261005	chr18_35337397_-	exonic
CAediting_1261006	chr18_35337406_-	exonic

Repat-regional RNA editing(s).

CAeditome ID

Position

Repeat family

Repeat sub family

Repeat name

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RNA A-to-I editing events in the alternative splicing sites for ZNF24

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000172466.14.ZNF24.

Correlation between RNA A-to-I editing and PSI for ENSG00000172466.14.ZNF24.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF24

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZNF24

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for ZNF24

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1261003	chr18_35337351_-	ENSG00000172466.14	ENST00000589881	hsa-miR-338-3p	35337347	35337353	7mer-m8	35337346	35337364	151.00	-17.78
CAediting_1261003	chr18_35337351_-	ENSG00000172466.14	ENST00000589881	hsa-miR-490-5p	35337351	35337357	7mer-m8	35337350	35337369	154.00	-18.74
CAediting_1261004	chr18_35337386_-	ENSG00000172466.14	ENST00000589881	hsa-miR-1180-3p	35337383	35337389	7mer-m8	35337382	35337403	145.00	-18.57
CAediting_1261005	chr18_35337397_-	ENSG00000172466.14	ENST00000589881	hsa-miR-1245b-5p	35337393	35337399	7mer-m8	35337392	35337411	149.00	-15.45
CAediting_1261005	chr18_35337397_-	ENSG00000172466.14	ENST00000589881	hsa-miR-3142	35337393	35337399	7mer-m8	35337392	35337411	161.00	-20.91
CAediting_1261005	chr18_35337397_-	ENSG00000172466.14	ENST00000589881	hsa-miR-4297	35337395	35337401	7mer-m8	35337394	35337409	145.00	-13.01
CAediting_1261005	chr18_35337397_-	ENSG00000172466.14	ENST00000589881	hsa-miR-5581-5p	35337395	35337401	7mer-m8	35337394	35337415	140.00	-13.76
CAediting_1261005	chr18_35337397_-	ENSG00000172466.14	ENST00000589881	hsa-miR-6734-3p	35337396	35337402	7mer-m8	35337395	35337417	154.00	-15.89

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1261006	chr18_35337406_-	ENSG00000172466.14	ENST00000589881	hsa-miR-181a-5p	35337403	35337409	7mer-m8	35337402	35337423	155	-15.27
CAediting_1261006	chr18_35337406_-	ENSG00000172466.14	ENST00000589881	hsa-miR-181a-5p	35337403	35337409	7mer-m8	35337402	35337423	155	-15.27
CAediting_1261006	chr18_35337406_-	ENSG00000172466.14	ENST00000589881	hsa-miR-181b-5p	35337403	35337409	7mer-m8	35337402	35337423	143	-13.62
CAediting_1261006	chr18_35337406_-	ENSG00000172466.14	ENST00000589881	hsa-miR-181b-5p	35337403	35337409	7mer-m8	35337402	35337423	143	-13.62
CAediting_1261006	chr18_35337406_-	ENSG00000172466.14	ENST00000589881	hsa-miR-181d-5p	35337403	35337409	7mer-m8	35337402	35337423	143	-12.47
CAediting_1261006	chr18_35337406_-	ENSG00000172466.14	ENST00000589881	hsa-miR-4262	35337403	35337409	7mer-m8	35337402	35337419	146	-11.26
CAediting_1261004	chr18_35337386_-	ENSG00000172466.14	ENST00000589881	hsa-miR-4794	35337384	35337391	8mer-1a	35337384	35337405	140	-20.34
CAediting_1261004	chr18_35337386_-	ENSG00000172466.14	ENST00000589881	hsa-miR-664a-5p	35337384	35337391	8mer-1a	35337384	35337407	147	-15.55

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000172466.14	ENST00000589881	hsa-miR-200b-3p	35337709	35337716	8mer-1a	35337709	35337730	140	-14.67
CAediting_393	chr1_1167164_+	ENSG00000172466.14	ENST00000589881	hsa-miR-200b-3p	35335872	35335877	6mer	35335871	35335892	140	-12.65
CAediting_688080	chr9_63819626_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4477b	35337663	35337670	8mer-1a	35337663	35337684	161	-17.43
CAediting_688081	chr9_63819627_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4477b	35338048	35338054	7mer-m8	35338047	35338070	149	-12.69
CAediting_393	chr1_1167164_+	ENSG00000172466.14	ENST00000399061	hsa-miR-200b-3p	35335872	35335877	6mer	35335871	35335892	140	-12.65
CAediting_1054808	chr15_66496985_-	ENSG00000172466.14	ENST00000589881	hsa-miR-4512	35338315	35338321	7mer-m8	35338314	35338334	158	-25.68
CAediting_1229414	chr17_67471546_+	ENSG00000172466.14	ENST00000589881	hsa-miR-548aa	35337010	35337016	7mer-1a	35337010	35337034	142	-9.37
CAediting_1229415	chr17_67471547_+	ENSG00000172466.14	ENST00000589881	hsa-miR-548aa	35336360	35336366	7mer-m8	35336359	35336384	154	-16.16
CAediting_1160181	chr17_7017644_-	ENSG00000172466.14	ENST00000589881	hsa-miR-195-3p	35334208	35334214	7mer-m8	35334207	35334227	147	-9.41
CAediting_1160181	chr17_7017644_-	ENSG00000172466.14	ENST00000589881	hsa-miR-195-3p	35338255	35338261	7mer-m8	35338254	35338275	152	-20.16
CAediting_228905	chr2_188297554_+	ENSG00000172466.14	ENST00000589881	hsa-miR-561-3p	35335648	35335654	7mer-m8	35335647	35335665	142	-14.97
CAediting_442554	chr5_154685830_+	ENSG00000172466.14	ENST00000589881	hsa-miR-1303	35336961	35336968	8mer-1a	35336961	35336983	147	-13.5
CAediting_442554	chr5_154685830_+	ENSG00000172466.14	ENST00000589881	hsa-miR-1303	35338707	35338713	7mer-m8	35338706	35338727	145	-16.98
CAediting_442554	chr5_154685830_+	ENSG00000172466.14	ENST00000589881	hsa-miR-1303	35333418	35333424	7mer-m8	35333417	35333439	167	-25.45
CAediting_1229414	chr17_67471546_+	ENSG00000172466.14	ENST00000399061	hsa-miR-548aa	35337010	35337016	7mer-1a	35337010	35337034	142	-9.37
CAediting_1229415	chr17_67471547_+	ENSG00000172466.14	ENST00000399061	hsa-miR-548aa	35336360	35336366	7mer-m8	35336359	35336384	154	-16.16
CAediting_1160181	chr17_7017644_-	ENSG00000172466.14	ENST00000399061	hsa-miR-195-3p	35334208	35334214	7mer-m8	35334207	35334227	147	-9.41
CAediting_228905	chr2_188297554_+	ENSG00000172466.14	ENST00000399061	hsa-miR-561-3p	35335648	35335654	7mer-m8	35335647	35335665	142	-14.97
CAediting_442554	chr5_154685830_+	ENSG00000172466.14	ENST00000399061	hsa-miR-1303	35336961	35336968	8mer-1a	35336961	35336983	147	-13.5
CAediting_442554	chr5_154685830_+	ENSG00000172466.14	ENST00000399061	hsa-miR-1303	35333418	35333424	7mer-m8	35333417	35333439	167	-25.45
CAediting_468389	chr6_31355314_-	ENSG00000172466.14	ENST00000589881	hsa-miR-6891-5p	35333937	35333943	7mer-m8	35333936	35333954	141	-16.31
CAediting_468389	chr6_31355314_-	ENSG00000172466.14	ENST00000399061	hsa-miR-6891-5p	35333937	35333943	7mer-m8	35333936	35333954	141	-16.31

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_573001	chr7_92204086_-	ENSG00000172466.14	ENST00000589881	hsa-miR-1285-5p	35335499	35335505	7mer-m8	35335498	35335518	151	-15.06
CAediting_573001	chr7_92204086_-	ENSG00000172466.14	ENST00000589881	hsa-miR-1285-5p	35332898	35332904	7mer-m8	35332897	35332917	150	-10.58
CAediting_442554	chr5_154685830_+	ENSG00000172466.14	ENST00000589881	hsa-miR-1303	35335879	35335885	7mer-m8	35335878	35335899	148	-12.91
CAediting_1368054	chr19_46709310_-	ENSG00000172466.14	ENST00000589881	hsa-miR-320e	35338308	35338315	8mer-1a	35338308	35338325	145	-13.32
CAediting_604450	chr7_133034877_-	ENSG00000172466.14	ENST00000589881	hsa-miR-3654	35333102	35333109	8mer-1a	35333102	35333123	148	-20.62
CAediting_77128	chr1_85133844_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4423-3p	35334689	35334695	7mer-m8	35334688	35334708	140	-11.31
CAediting_77128	chr1_85133844_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4423-3p	35332426	35332433	8mer-1a	35332426	35332446	140	-11.58
CAediting_688080	chr9_63819626_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4477b	35338566	35338572	7mer-m8	35338565	35338586	140	-8.71
CAediting_688081	chr9_63819627_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4477b	35338566	35338572	7mer-m8	35338565	35338586	140	-8.71
CAediting_688080	chr9_63819626_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4477b	35333625	35333632	8mer-1a	35333625	35333644	153	-8.16
CAediting_688081	chr9_63819627_+	ENSG00000172466.14	ENST00000589881	hsa-miR-4477b	35333625	35333632	8mer-1a	35333625	35333644	153	-8.16
CAediting_1054808	chr15_66496985_-	ENSG00000172466.14	ENST00000589881	hsa-miR-4512	35332443	35332450	8mer-1a	35332443	35332464	145	-16.51
CAediting_228905	chr2_188297554_+	ENSG00000172466.14	ENST00000589881	hsa-miR-561-3p	35338374	35338380	7mer-m8	35338373	35338394	140	-8.42
CAediting_524911	chr7_5495852_-	ENSG00000172466.14	ENST00000589881	hsa-miR-589-3p	35338272	35338278	7mer-m8	35338271	35338294	146	-9.86
CAediting_1351755	chr19_40282625_-	ENSG00000172466.14	ENST00000589881	hsa-miR-641	35337409	35337415	7mer-m8	35337408	35337430	148	-11.15
CAediting_1399425	chr20_1392958_-	ENSG00000172466.14	ENST00000589881	hsa-miR-6869-5p	35336554	35336560	7mer-m8	35336553	35336574	141	-13.97
CAediting_573001	chr7_92204086_-	ENSG00000172466.14	ENST00000399061	hsa-miR-1285-5p	35335499	35335505	7mer-m8	35335498	35335518	151	-15.06
CAediting_573001	chr7_92204086_-	ENSG00000172466.14	ENST00000399061	hsa-miR-1285-5p	35332898	35332904	7mer-m8	35332897	35332917	150	-10.58
CAediting_442554	chr5_154685830_+	ENSG00000172466.14	ENST00000399061	hsa-miR-1303	35335879	35335885	7mer-m8	35335878	35335899	148	-12.91
CAediting_604450	chr7_133034877_-	ENSG00000172466.14	ENST00000399061	hsa-miR-3654	35333102	35333109	8mer-1a	35333102	35333123	148	-20.62
CAediting_77128	chr1_85133844_+	ENSG00000172466.14	ENST00000399061	hsa-miR-4423-3p	35334689	35334695	7mer-m8	35334688	35334708	140	-11.31
CAediting_77128	chr1_85133844_+	ENSG00000172466.14	ENST00000399061	hsa-miR-4423-3p	35332426	35332433	8mer-1a	35332426	35332446	140	-11.58
CAediting_688080	chr9_63819626_+	ENSG00000172466.14	ENST00000399061	hsa-miR-4477b	35333625	35333632	8mer-1a	35333625	35333644	153	-8.16
CAediting_688081	chr9_63819627_+	ENSG00000172466.14	ENST00000399061	hsa-miR-4477b	35333625	35333632	8mer-1a	35333625	35333644	153	-8.16
CAediting_1399425	chr20_1392958_-	ENSG00000172466.14	ENST00000399061	hsa-miR-6869-5p	35336554	35336560	7mer-m8	35336553	35336574	141	-13.97

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF24

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for ZNF24

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for ZNF24

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for ZNF24

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for ZNF24

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for ZNF24

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene