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Center for Computational Systems Medicine
Soverview

Gene summary

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RNA A-to-I events

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Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

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The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

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Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: ZNF14 (CAeditome ID:7561)

Gene summary for ZNF14

check button Gene summary
Gene informationGene symbol

ZNF14

Gene ID

7561

Gene namezinc finger protein 14
SynonymsGIOT-4|KOX6
Cytomap

19p13.11

Type of geneprotein-coding
Descriptionzinc finger protein 14gonadotropin inducible transcription repressor-4gonadotropin-inducible ovary transcription repressor 4zinc finger protein 14 (KOX 6)zinc finger protein KOX6
Modification date20210518
UniProtAcc

P17017

Context- 26544568(Outlier Analysis Defines Zinc Finger Gene Family DNA Methylation in Tumors and Saliva of Head and Neck Cancer Patients)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ZNF14

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000105708.8

check button RNA A-to-I editing events in Cancer.
CAediting_1323268(19710800, -), CAediting_1323269(19710801, -), CAediting_1323270(19710853, -), CAediting_1323271(19710878, -), CAediting_1323272(19710883, -), CAediting_1323273(19710904, -), CAediting_1323274(19710905, -), CAediting_1323275(19710918, -), CAediting_1323276(19710923, -), CAediting_1323277(19710927, -), CAediting_1323278(19710930, -), CAediting_1323279(19710934, -), CAediting_1323280(19710947, -), CAediting_1323281(19710948, -), CAediting_1323282(19710971, -), CAediting_1323283(19710973, -), CAediting_1323284(19710994, -), CAediting_1323285(19710995, -), CAediting_1323286(19711012, -), CAediting_1323287(19711027, -), CAediting_1323288(19711050, -), CAediting_1323289(19711052, -), CAediting_1323290(19711058, -), CAediting_1323291(19712678, -), CAediting_1323292(19714772, -), CAediting_1323293(19714803, -), CAediting_1323294(19716485, -), CAediting_1323295(19721223, -), CAediting_1323296(19721228, -), CAediting_1323297(19721229, -), CAediting_1323298(19729408, -), CAediting_1323299(19731562, -),

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RNA editing positional annotations for ZNF14 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1323268chr19_19710800_-UTR3
CAediting_1323269chr19_19710801_-UTR3
CAediting_1323270chr19_19710853_-UTR3
CAediting_1323271chr19_19710878_-UTR3
CAediting_1323272chr19_19710883_-UTR3
CAediting_1323273chr19_19710904_-UTR3
CAediting_1323274chr19_19710905_-UTR3
CAediting_1323275chr19_19710918_-UTR3
CAediting_1323276chr19_19710923_-UTR3
CAediting_1323277chr19_19710927_-UTR3
CAediting_1323278chr19_19710930_-UTR3
CAediting_1323279chr19_19710934_-UTR3
CAediting_1323280chr19_19710947_-UTR3
CAediting_1323281chr19_19710948_-UTR3
CAediting_1323282chr19_19710971_-UTR3
CAediting_1323283chr19_19710973_-UTR3
CAediting_1323284chr19_19710994_-UTR3
CAediting_1323285chr19_19710995_-UTR3
CAediting_1323286chr19_19711012_-UTR3
CAediting_1323287chr19_19711027_-UTR3
CAediting_1323288chr19_19711050_-UTR3
CAediting_1323289chr19_19711052_-UTR3
CAediting_1323290chr19_19711058_-UTR3
CAediting_1323291chr19_19712678_-exonic
CAediting_1323292chr19_19714772_-intronic
CAediting_1323293chr19_19714803_-intronic
CAediting_1323294chr19_19716485_-intronic
CAediting_1323295chr19_19721223_-intronic
CAediting_1323296chr19_19721228_-intronic
CAediting_1323297chr19_19721229_-intronic
CAediting_1323298chr19_19729408_-intronic
CAediting_1323299chr19_19731562_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1323268chr19_19710800_-SINEAluAluSz
CAediting_1323269chr19_19710801_-SINEAluAluSz
CAediting_1323270chr19_19710853_-SINEAluAluSz
CAediting_1323271chr19_19710878_-SINEAluAluSz
CAediting_1323272chr19_19710883_-SINEAluAluSz
CAediting_1323273chr19_19710904_-SINEAluAluSz
CAediting_1323274chr19_19710905_-SINEAluAluSz
CAediting_1323275chr19_19710918_-SINEAluAluSz
CAediting_1323276chr19_19710923_-SINEAluAluSz
CAediting_1323277chr19_19710927_-SINEAluAluSz
CAediting_1323278chr19_19710930_-SINEAluAluSz
CAediting_1323279chr19_19710934_-SINEAluAluSz
CAediting_1323280chr19_19710947_-SINEAluAluSz
CAediting_1323281chr19_19710948_-SINEAluAluSz
CAediting_1323282chr19_19710971_-SINEAluAluSz
CAediting_1323283chr19_19710973_-SINEAluAluSz
CAediting_1323284chr19_19710994_-SINEAluAluSz
CAediting_1323285chr19_19710995_-SINEAluAluSz
CAediting_1323286chr19_19711012_-SINEAluAluSz
CAediting_1323287chr19_19711027_-SINEAluAluSz
CAediting_1323288chr19_19711050_-SINEAluAluSz
CAediting_1323289chr19_19711052_-SINEAluAluSz
CAediting_1323290chr19_19711058_-SINEAluAluSz
CAediting_1323292chr19_19714772_-SINEAluAluSx
CAediting_1323293chr19_19714803_-SINEAluAluSx
CAediting_1323294chr19_19716485_-SINEAluAluSz6
CAediting_1323295chr19_19721223_-SINEAluAluSg
CAediting_1323296chr19_19721228_-SINEAluAluSg
CAediting_1323297chr19_19721229_-SINEAluAluSg
CAediting_1323298chr19_19729408_-SINEAluAluSx1
CAediting_1323299chr19_19731562_-SINEAluAluSx1

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RNA A-to-I editing events in the alternative splicing sites for ZNF14

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000105708.8.ZNF14.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000105708.8.ZNF14.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZNF14

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZNF14

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for ZNF14

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZNF14

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZNF14

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ZNF14

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ZNF14

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ZNF14

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZNF14

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource