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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: ZIC2 (CAeditome ID:7546) |
Gene summary for ZIC2 |
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Gene information | Gene symbol | ZIC2 | Gene ID | 7546 |
Gene name | Zic family member 2 | |
Synonyms | HPE5 | |
Cytomap | 13q32.3 | |
Type of gene | protein-coding | |
Description | zinc finger protein ZIC 2Zic family member 2 (odd-paired homolog, Drosophila)Zinc finger protein of the cerebellum 2 | |
Modification date | 20210518 | |
UniProtAcc | O95409 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
ZIC2 | GO:0005654 | Zinc finger protein ZIC 2 | 0000052 |
ZIC2 | GO:0016604 | Zinc finger protein ZIC 2 | 0000052 |
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RNA A-to-I events for ZIC2 |
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CAediting_971550(99982768, +), CAediting_971551(99982888, +), CAediting_971552(99983046, +), |
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RNA editing positional annotations for ZIC2 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_971550 | chr13_99982768_+ | nonsynonymous SNV | ENST00000376335.6 | c.A704G | p.H235R | D | D | N |
CAediting_971552 | chr13_99983046_+ | nonsynonymous SNV | ENST00000376335.6 | c.A982G | p.T328A | D | P | D |
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CAeditome ID | Position | Variant type |
CAediting_971550 | chr13_99982768_+ | exonic |
CAediting_971551 | chr13_99982888_+ | exonic |
CAediting_971552 | chr13_99983046_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_971550 | chr13_99982768_+ | Simple_repeat | Simple_repeat | (CCA)n |
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RNA A-to-I editing events in the alternative splicing sites for ZIC2 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZIC2 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for ZIC2 |
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The effects of the RNA editing to the miRNA binding sites for ZIC2 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for ZIC2 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for ZIC2 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for ZIC2 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for ZIC2 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for ZIC2 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ZIC2 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
ZIC2 | C1864827 | HOLOPROSENCEPHALY 5 | 8 | CTD_human;GENOMICS_ENGLAND;UNIPROT |
ZIC2 | C0011999 | Diastematomyelia | 1 | CTD_human |
ZIC2 | C0027794 | Neural Tube Defects | 1 | CTD_human |
ZIC2 | C0027806 | Neurenteric Cyst | 1 | CTD_human |
ZIC2 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
ZIC2 | C0036341 | Schizophrenia | 1 | PSYGENET |
ZIC2 | C0080218 | Tethered Cord Syndrome | 1 | CTD_human |
ZIC2 | C0152234 | Iniencephaly | 1 | CTD_human |
ZIC2 | C0152426 | Craniorachischisis | 1 | CTD_human |
ZIC2 | C0266453 | Exencephaly | 1 | CTD_human |
ZIC2 | C0344479 | Spinal Cord Myelodysplasia | 1 | CTD_human |
ZIC2 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
ZIC2 | C0702169 | Acrania | 1 | CTD_human |
ZIC2 | C2239176 | Liver carcinoma | 1 | CTD_human |