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Editing gene: XRCC2 (CAeditome ID:7516)

Gene summary for XRCC2

Gene summary

Gene information	Gene symbol	XRCC2
	Gene ID	7516
	Gene name	X-ray repair cross complementing 2
	Synonyms	FANCU\|POF17\|SPGF50
	Cytomap	7q36.1
	Type of gene	protein-coding
	Description	DNA repair protein XRCC2X-ray repair complementing defective repair in Chinese hamster cells 2X-ray repair cross-complementing protein 2epididymis secretory sperm binding protein
	Modification date	20210518
	UniProtAcc	O43543
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
XRCC2	GO:0000400	DNA repair protein XRCC2	20207730
XRCC2	GO:0042148	DNA repair protein XRCC2	11834724
XRCC2	GO:0005654	DNA repair protein XRCC2	0000052
XRCC2	GO:0005657	DNA repair protein XRCC2	20207730
XRCC2	GO:0005813	DNA repair protein XRCC2	21276791
XRCC2	GO:0043231	DNA repair protein XRCC2	0000052
XRCC2	GO:0033063	DNA repair protein XRCC2	11751635

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RNA A-to-I events for XRCC2

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000196584.2

RNA A-to-I editing events in Cancer.

CAediting_613676(152645302, -), CAediting_613677(152645307, -), CAediting_613678(152645326, -), CAediting_613679(152645327, -), CAediting_613680(152645352, -), CAediting_613681(152645356, -), CAediting_613682(152645359, -), CAediting_613683(152645360, -), CAediting_613684(152645365, -), CAediting_613685(152645373, -), CAediting_613686(152645376, -), CAediting_613687(152645381, -), CAediting_613688(152645382, -), CAediting_613689(152645387, -), CAediting_613690(152645388, -), CAediting_613691(152645398, -), CAediting_613692(152645403, -), CAediting_613693(152645409, -), CAediting_613694(152645774, -), CAediting_613695(152645794, -), CAediting_613696(152645796, -), CAediting_613697(152645799, -), CAediting_613698(152645809, -), CAediting_613699(152645810, -), CAediting_613700(152645818, -), CAediting_613701(152645823, -), CAediting_613702(152645847, -), CAediting_613703(152645848, -), CAediting_613704(152645860, -), CAediting_613705(152645864, -), CAediting_613706(152645865, -), CAediting_613707(152645907, -), CAediting_613708(152645908, -), CAediting_613709(152645912, -), CAediting_613710(152645914, -), CAediting_613711(152645920, -), CAediting_613712(152646544, -), CAediting_613713(152646549, -), CAediting_613714(152646566, -), CAediting_613715(152646569, -), CAediting_613716(152646573, -), CAediting_613717(152646574, -), CAediting_613718(152646583, -), CAediting_613719(152646588, -), CAediting_613720(152646592, -), CAediting_613721(152646598, -), CAediting_613722(152646601, -), CAediting_613723(152646605, -), CAediting_613724(152646609, -), CAediting_613725(152646641, -), CAediting_613726(152646645, -), CAediting_613727(152646646, -), CAediting_613728(152646649, -), CAediting_613729(152646651, -), CAediting_613730(152646655, -), CAediting_613731(152646656, -), CAediting_613732(152646659, -), CAediting_613733(152646665, -), CAediting_613734(152646670, -), CAediting_613735(152646680, -), CAediting_613736(152646693, -), CAediting_613737(152646695, -), CAediting_613738(152646696, -), CAediting_613739(152646704, -), CAediting_613740(152646727, -), CAediting_613741(152646733, -), CAediting_613742(152646741, -), CAediting_613743(152646744, -), CAediting_613744(152646749, -), CAediting_613745(152646758, -), CAediting_613746(152648156, -), CAediting_613747(152648162, -), CAediting_613748(152648163, -), CAediting_613749(152648189, -), CAediting_613750(152648190, -), CAediting_613751(152648224, -), CAediting_613752(152648227, -), CAediting_613753(152648237, -), CAediting_613754(152648239, -), CAediting_613755(152648243, -), CAediting_613756(152648244, -), CAediting_613757(152648258, -), CAediting_613758(152648259, -), CAediting_613759(152648272, -), CAediting_613760(152648279, -), CAediting_613761(152648283, -), CAediting_613762(152648295, -), CAediting_613763(152648307, -), CAediting_613764(152648312, -), CAediting_613765(152648320, -), CAediting_613766(152648324, -), CAediting_613767(152648345, -), CAediting_613768(152648361, -), CAediting_613769(152648363, -), CAediting_613770(152648369, -), CAediting_613771(152648396, -), CAediting_613772(152651936, -), CAediting_613773(152653708, -), CAediting_613774(152654151, -), CAediting_613775(152656339, -), CAediting_613776(152656980, -), CAediting_613777(152657112, -), CAediting_613778(152657114, -), CAediting_613779(152657437, -), CAediting_613780(152658398, -), CAediting_613781(152665583, -), CAediting_613782(152665618, -), CAediting_613783(152665768, -),

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RNA editing positional annotations for XRCC2 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_613676	chr7_152645302_-	ncRNA_exonic
CAediting_613677	chr7_152645307_-	ncRNA_exonic
CAediting_613678	chr7_152645326_-	ncRNA_exonic
CAediting_613679	chr7_152645327_-	ncRNA_exonic
CAediting_613680	chr7_152645352_-	ncRNA_exonic
CAediting_613681	chr7_152645356_-	ncRNA_exonic
CAediting_613682	chr7_152645359_-	ncRNA_exonic
CAediting_613683	chr7_152645360_-	ncRNA_exonic
CAediting_613684	chr7_152645365_-	ncRNA_exonic
CAediting_613685	chr7_152645373_-	ncRNA_exonic
CAediting_613686	chr7_152645376_-	ncRNA_exonic
CAediting_613687	chr7_152645381_-	ncRNA_exonic
CAediting_613688	chr7_152645382_-	ncRNA_exonic
CAediting_613689	chr7_152645387_-	ncRNA_exonic
CAediting_613690	chr7_152645388_-	ncRNA_exonic
CAediting_613691	chr7_152645398_-	ncRNA_exonic
CAediting_613692	chr7_152645403_-	ncRNA_exonic
CAediting_613693	chr7_152645409_-	ncRNA_exonic
CAediting_613694	chr7_152645774_-	ncRNA_exonic
CAediting_613695	chr7_152645794_-	ncRNA_exonic
CAediting_613696	chr7_152645796_-	ncRNA_exonic
CAediting_613697	chr7_152645799_-	ncRNA_exonic
CAediting_613698	chr7_152645809_-	ncRNA_exonic
CAediting_613699	chr7_152645810_-	ncRNA_exonic
CAediting_613700	chr7_152645818_-	ncRNA_exonic
CAediting_613701	chr7_152645823_-	ncRNA_exonic
CAediting_613702	chr7_152645847_-	ncRNA_exonic
CAediting_613703	chr7_152645848_-	ncRNA_exonic
CAediting_613704	chr7_152645860_-	ncRNA_exonic
CAediting_613705	chr7_152645864_-	ncRNA_exonic
CAediting_613706	chr7_152645865_-	ncRNA_exonic
CAediting_613707	chr7_152645907_-	ncRNA_exonic
CAediting_613708	chr7_152645908_-	ncRNA_exonic
CAediting_613709	chr7_152645912_-	ncRNA_exonic
CAediting_613710	chr7_152645914_-	ncRNA_exonic
CAediting_613711	chr7_152645920_-	ncRNA_exonic
CAediting_613712	chr7_152646544_-	ncRNA_exonic
CAediting_613713	chr7_152646549_-	ncRNA_exonic
CAediting_613714	chr7_152646566_-	ncRNA_exonic
CAediting_613715	chr7_152646569_-	ncRNA_exonic
CAediting_613716	chr7_152646573_-	ncRNA_exonic
CAediting_613717	chr7_152646574_-	ncRNA_exonic
CAediting_613718	chr7_152646583_-	ncRNA_exonic
CAediting_613719	chr7_152646588_-	ncRNA_exonic
CAediting_613720	chr7_152646592_-	ncRNA_exonic
CAediting_613721	chr7_152646598_-	ncRNA_exonic
CAediting_613722	chr7_152646601_-	ncRNA_exonic
CAediting_613723	chr7_152646605_-	ncRNA_exonic
CAediting_613724	chr7_152646609_-	ncRNA_exonic
CAediting_613725	chr7_152646641_-	ncRNA_exonic
CAediting_613726	chr7_152646645_-	ncRNA_exonic
CAediting_613727	chr7_152646646_-	ncRNA_exonic
CAediting_613728	chr7_152646649_-	ncRNA_exonic
CAediting_613729	chr7_152646651_-	ncRNA_exonic
CAediting_613730	chr7_152646655_-	ncRNA_exonic
CAediting_613731	chr7_152646656_-	ncRNA_exonic
CAediting_613732	chr7_152646659_-	ncRNA_exonic
CAediting_613733	chr7_152646665_-	ncRNA_exonic
CAediting_613734	chr7_152646670_-	ncRNA_exonic
CAediting_613735	chr7_152646680_-	ncRNA_exonic
CAediting_613736	chr7_152646693_-	ncRNA_exonic
CAediting_613737	chr7_152646695_-	ncRNA_exonic
CAediting_613738	chr7_152646696_-	ncRNA_exonic
CAediting_613739	chr7_152646704_-	ncRNA_exonic
CAediting_613740	chr7_152646727_-	ncRNA_exonic
CAediting_613741	chr7_152646733_-	ncRNA_exonic
CAediting_613742	chr7_152646741_-	ncRNA_exonic
CAediting_613743	chr7_152646744_-	ncRNA_exonic
CAediting_613744	chr7_152646749_-	ncRNA_exonic
CAediting_613745	chr7_152646758_-	ncRNA_exonic
CAediting_613746	chr7_152648156_-	ncRNA_exonic
CAediting_613747	chr7_152648162_-	ncRNA_exonic
CAediting_613748	chr7_152648163_-	ncRNA_exonic
CAediting_613749	chr7_152648189_-	ncRNA_exonic
CAediting_613750	chr7_152648190_-	ncRNA_exonic
CAediting_613751	chr7_152648224_-	ncRNA_exonic
CAediting_613752	chr7_152648227_-	ncRNA_exonic
CAediting_613753	chr7_152648237_-	ncRNA_exonic
CAediting_613754	chr7_152648239_-	ncRNA_exonic
CAediting_613755	chr7_152648243_-	ncRNA_exonic
CAediting_613756	chr7_152648244_-	ncRNA_exonic
CAediting_613757	chr7_152648258_-	ncRNA_exonic
CAediting_613758	chr7_152648259_-	ncRNA_exonic
CAediting_613759	chr7_152648272_-	ncRNA_exonic
CAediting_613760	chr7_152648279_-	ncRNA_exonic
CAediting_613761	chr7_152648283_-	ncRNA_exonic
CAediting_613762	chr7_152648295_-	ncRNA_exonic
CAediting_613763	chr7_152648307_-	ncRNA_exonic
CAediting_613764	chr7_152648312_-	ncRNA_exonic
CAediting_613765	chr7_152648320_-	ncRNA_exonic
CAediting_613766	chr7_152648324_-	ncRNA_exonic
CAediting_613767	chr7_152648345_-	ncRNA_exonic
CAediting_613768	chr7_152648361_-	ncRNA_exonic
CAediting_613769	chr7_152648363_-	ncRNA_exonic
CAediting_613770	chr7_152648369_-	ncRNA_exonic
CAediting_613771	chr7_152648396_-	ncRNA_exonic
CAediting_613772	chr7_152651936_-	ncRNA_intronic
CAediting_613773	chr7_152653708_-	ncRNA_intronic
CAediting_613774	chr7_152654151_-	ncRNA_intronic
CAediting_613775	chr7_152656339_-	ncRNA_intronic
CAediting_613776	chr7_152656980_-	ncRNA_intronic
CAediting_613777	chr7_152657112_-	ncRNA_intronic
CAediting_613778	chr7_152657114_-	ncRNA_intronic
CAediting_613779	chr7_152657437_-	ncRNA_intronic
CAediting_613780	chr7_152658398_-	ncRNA_intronic
CAediting_613781	chr7_152665583_-	intronic
CAediting_613782	chr7_152665618_-	intronic
CAediting_613783	chr7_152665768_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_613676	chr7_152645302_-	SINE	Alu	AluJo
CAediting_613677	chr7_152645307_-	SINE	Alu	AluJo
CAediting_613678	chr7_152645326_-	SINE	Alu	AluJo
CAediting_613679	chr7_152645327_-	SINE	Alu	AluJo
CAediting_613680	chr7_152645352_-	SINE	Alu	AluJo
CAediting_613681	chr7_152645356_-	SINE	Alu	AluJo
CAediting_613682	chr7_152645359_-	SINE	Alu	AluJo
CAediting_613683	chr7_152645360_-	SINE	Alu	AluJo
CAediting_613684	chr7_152645365_-	SINE	Alu	AluJo
CAediting_613685	chr7_152645373_-	SINE	Alu	AluJo
CAediting_613686	chr7_152645376_-	SINE	Alu	AluJo
CAediting_613687	chr7_152645381_-	SINE	Alu	AluJo
CAediting_613688	chr7_152645382_-	SINE	Alu	AluJo
CAediting_613689	chr7_152645387_-	SINE	Alu	AluJo
CAediting_613690	chr7_152645388_-	SINE	Alu	AluJo
CAediting_613691	chr7_152645398_-	SINE	Alu	AluJo
CAediting_613692	chr7_152645403_-	SINE	Alu	AluJo
CAediting_613693	chr7_152645409_-	LINE	L1	L1ME3D
CAediting_613694	chr7_152645774_-	SINE	Alu	AluJo
CAediting_613695	chr7_152645794_-	SINE	Alu	AluJo
CAediting_613696	chr7_152645796_-	SINE	Alu	AluJo
CAediting_613697	chr7_152645799_-	SINE	Alu	AluJo
CAediting_613698	chr7_152645809_-	SINE	Alu	AluJo
CAediting_613699	chr7_152645810_-	SINE	Alu	AluJo
CAediting_613700	chr7_152645818_-	SINE	Alu	AluJo
CAediting_613701	chr7_152645823_-	SINE	Alu	AluJo
CAediting_613702	chr7_152645847_-	SINE	Alu	AluJo
CAediting_613703	chr7_152645848_-	SINE	Alu	AluJo
CAediting_613704	chr7_152645860_-	SINE	Alu	AluJo
CAediting_613705	chr7_152645864_-	SINE	Alu	AluJo
CAediting_613706	chr7_152645865_-	SINE	Alu	AluJo
CAediting_613707	chr7_152645907_-	SINE	Alu	AluJo
CAediting_613708	chr7_152645908_-	SINE	Alu	AluJo
CAediting_613709	chr7_152645912_-	SINE	Alu	AluJo
CAediting_613710	chr7_152645914_-	SINE	Alu	AluJo
CAediting_613711	chr7_152645920_-	SINE	Alu	AluJo
CAediting_613712	chr7_152646544_-	SINE	Alu	AluSx3
CAediting_613713	chr7_152646549_-	SINE	Alu	AluSx3
CAediting_613714	chr7_152646566_-	SINE	Alu	AluSx3
CAediting_613715	chr7_152646569_-	SINE	Alu	AluSx3
CAediting_613716	chr7_152646573_-	SINE	Alu	AluSx3
CAediting_613717	chr7_152646574_-	SINE	Alu	AluSx3
CAediting_613718	chr7_152646583_-	SINE	Alu	AluSx3
CAediting_613719	chr7_152646588_-	SINE	Alu	AluSx3
CAediting_613720	chr7_152646592_-	SINE	Alu	AluSx3
CAediting_613721	chr7_152646598_-	SINE	Alu	AluSx3
CAediting_613722	chr7_152646601_-	SINE	Alu	AluSx3
CAediting_613723	chr7_152646605_-	SINE	Alu	AluSx3
CAediting_613724	chr7_152646609_-	SINE	Alu	AluSx3
CAediting_613725	chr7_152646641_-	SINE	Alu	AluSx3
CAediting_613726	chr7_152646645_-	SINE	Alu	AluSx3
CAediting_613727	chr7_152646646_-	SINE	Alu	AluSx3
CAediting_613728	chr7_152646649_-	SINE	Alu	AluSx3
CAediting_613729	chr7_152646651_-	SINE	Alu	AluSx3
CAediting_613730	chr7_152646655_-	SINE	Alu	AluSx3
CAediting_613731	chr7_152646656_-	SINE	Alu	AluSx3
CAediting_613732	chr7_152646659_-	SINE	Alu	AluSx3
CAediting_613733	chr7_152646665_-	SINE	Alu	AluSx3
CAediting_613734	chr7_152646670_-	SINE	Alu	AluSx3
CAediting_613735	chr7_152646680_-	SINE	Alu	AluSx3
CAediting_613736	chr7_152646693_-	SINE	Alu	AluSx3
CAediting_613737	chr7_152646695_-	SINE	Alu	AluSx3
CAediting_613738	chr7_152646696_-	SINE	Alu	AluSx3
CAediting_613739	chr7_152646704_-	SINE	Alu	AluSx3
CAediting_613740	chr7_152646727_-	SINE	Alu	AluSx3
CAediting_613741	chr7_152646733_-	SINE	Alu	AluSx3
CAediting_613742	chr7_152646741_-	SINE	Alu	AluSx3
CAediting_613743	chr7_152646744_-	SINE	Alu	AluSx3
CAediting_613744	chr7_152646749_-	SINE	Alu	AluSx3
CAediting_613745	chr7_152646758_-	SINE	Alu	AluSx3
CAediting_613746	chr7_152648156_-	SINE	Alu	AluSx1
CAediting_613747	chr7_152648162_-	SINE	Alu	AluSx1
CAediting_613748	chr7_152648163_-	SINE	Alu	AluSx1
CAediting_613749	chr7_152648189_-	SINE	Alu	AluSx1
CAediting_613750	chr7_152648190_-	SINE	Alu	AluSx1
CAediting_613751	chr7_152648224_-	SINE	Alu	AluSx1
CAediting_613752	chr7_152648227_-	SINE	Alu	AluSx1
CAediting_613753	chr7_152648237_-	SINE	Alu	AluSx1
CAediting_613754	chr7_152648239_-	SINE	Alu	AluSx1
CAediting_613755	chr7_152648243_-	SINE	Alu	AluSx1
CAediting_613756	chr7_152648244_-	SINE	Alu	AluSx1
CAediting_613757	chr7_152648258_-	SINE	Alu	AluSx1
CAediting_613758	chr7_152648259_-	SINE	Alu	AluSx1
CAediting_613759	chr7_152648272_-	SINE	Alu	AluSx1
CAediting_613760	chr7_152648279_-	SINE	Alu	AluSx1
CAediting_613761	chr7_152648283_-	SINE	Alu	AluSx1
CAediting_613762	chr7_152648295_-	SINE	Alu	AluSx1
CAediting_613763	chr7_152648307_-	SINE	Alu	AluSx1
CAediting_613764	chr7_152648312_-	SINE	Alu	AluSx1
CAediting_613765	chr7_152648320_-	SINE	Alu	AluSx1
CAediting_613766	chr7_152648324_-	SINE	Alu	AluSx1
CAediting_613767	chr7_152648345_-	SINE	Alu	AluSx1
CAediting_613768	chr7_152648361_-	SINE	Alu	AluSx1
CAediting_613769	chr7_152648363_-	SINE	Alu	AluSx1
CAediting_613770	chr7_152648369_-	SINE	Alu	AluSx1
CAediting_613771	chr7_152648396_-	SINE	Alu	AluSx1
CAediting_613772	chr7_152651936_-	SINE	Alu	AluJb
CAediting_613773	chr7_152653708_-	SINE	Alu	AluJb
CAediting_613774	chr7_152654151_-	SINE	Alu	AluSp
CAediting_613775	chr7_152656339_-	SINE	Alu	AluSx
CAediting_613776	chr7_152656980_-	SINE	Alu	AluSx
CAediting_613777	chr7_152657112_-	SINE	Alu	AluSx
CAediting_613778	chr7_152657114_-	SINE	Alu	AluSx
CAediting_613779	chr7_152657437_-	SINE	Alu	AluSx1
CAediting_613780	chr7_152658398_-	SINE	Alu	AluSx1
CAediting_613781	chr7_152665583_-	SINE	Alu	AluJb
CAediting_613782	chr7_152665618_-	SINE	Alu	AluJb
CAediting_613783	chr7_152665768_-	SINE	Alu	AluJb

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RNA A-to-I editing events in the alternative splicing sites for XRCC2

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	CAediting_613695	chr7_152645794_-	152645786:152645794	5SS	3+0i	AGGTGTGTG	-24.26	GGGTGTGTG	-27.58
IR	CAediting_613695	chr7_152645794_-	152645786:152645794	5SS	3+0i	AGGTGTGTG	-24.26	GGGTGTGTG	-27.58
ES	CAediting_613777	chr7_152657112_-	152657104:152657112	5SS	3+0i	AGGTGTGTG	-24.26	GGGTGTGTG	-27.58
MEX_2	CAediting_613777	chr7_152657112_-	152657104:152657112	5SS	3+0i	AGGTGTGTG	-24.26	GGGTGTGTG	-27.58

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000196584.2.XRCC2.

Correlation between RNA A-to-I editing and PSI for ENSG00000196584.2.XRCC2.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for XRCC2

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LUSC.CAediting_613700.ENSG00000196584.XRCC2.png
Soverview

SARC.CAediting_613683.ENSG00000196584.XRCC2.png
Soverview

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Protein coding region RNA A-to-I editings for XRCC2

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for XRCC2

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for XRCC2

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000495707.1	processed_transcript
ENST00000359321.1	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_613676	ENST00000495707.1	chr7_152645302_-	-1434.70	-1435.60	-1504.80
CAediting_613677	ENST00000495707.1	chr7_152645307_-	-1435.80	-1435.60	-1504.80
CAediting_613678	ENST00000495707.1	chr7_152645326_-	-1435.30	-1435.60	-1504.80
CAediting_613679	ENST00000495707.1	chr7_152645327_-	-1435.30	-1435.60	-1504.80
CAediting_613680	ENST00000495707.1	chr7_152645352_-	-1434.70	-1435.60	-1504.80
CAediting_613681	ENST00000495707.1	chr7_152645356_-	-1436.40	-1435.60	-1504.80
CAediting_613682	ENST00000495707.1	chr7_152645359_-	-1437.00	-1435.60	-1504.80
CAediting_613683	ENST00000495707.1	chr7_152645360_-	-1435.60	-1435.60	-1504.80
CAediting_613684	ENST00000495707.1	chr7_152645365_-	-1434.70	-1435.60	-1504.80
CAediting_613685	ENST00000495707.1	chr7_152645373_-	-1435.20	-1435.60	-1504.80
CAediting_613686	ENST00000495707.1	chr7_152645376_-	-1436.00	-1435.60	-1504.80
CAediting_613687	ENST00000495707.1	chr7_152645381_-	-1435.60	-1435.60	-1504.80
CAediting_613688	ENST00000495707.1	chr7_152645382_-	-1435.70	-1435.60	-1504.80
CAediting_613689	ENST00000495707.1	chr7_152645387_-	-1436.00	-1435.60	-1504.80
CAediting_613690	ENST00000495707.1	chr7_152645388_-	-1437.60	-1435.60	-1504.80
CAediting_613691	ENST00000495707.1	chr7_152645398_-	-1434.90	-1435.60	-1504.80
CAediting_613692	ENST00000495707.1	chr7_152645403_-	-1436.80	-1435.60	-1504.80
CAediting_613693	ENST00000495707.1	chr7_152645409_-	-1437.20	-1435.60	-1504.80
CAediting_613694	ENST00000495707.1	chr7_152645774_-	-1437.10	-1435.60	-1504.80
CAediting_613695	ENST00000495707.1	chr7_152645794_-	-1435.60	-1435.60	-1504.80
CAediting_613696	ENST00000495707.1	chr7_152645796_-	-1437.10	-1435.60	-1504.80
CAediting_613697	ENST00000495707.1	chr7_152645799_-	-1437.70	-1435.60	-1504.80
CAediting_613698	ENST00000495707.1	chr7_152645809_-	-1436.90	-1435.60	-1504.80
CAediting_613699	ENST00000495707.1	chr7_152645810_-	-1438.20	-1435.60	-1504.80
CAediting_613700	ENST00000495707.1	chr7_152645818_-	-1434.90	-1435.60	-1504.80
CAediting_613701	ENST00000495707.1	chr7_152645823_-	-1436.00	-1435.60	-1504.80
CAediting_613702	ENST00000495707.1	chr7_152645847_-	-1438.30	-1435.60	-1504.80
CAediting_613703	ENST00000495707.1	chr7_152645848_-	-1436.70	-1435.60	-1504.80
CAediting_613704	ENST00000495707.1	chr7_152645860_-	-1435.20	-1435.60	-1504.80
CAediting_613705	ENST00000495707.1	chr7_152645864_-	-1439.30	-1435.60	-1504.80
CAediting_613706	ENST00000495707.1	chr7_152645865_-	-1435.60	-1435.60	-1504.80
CAediting_613707	ENST00000495707.1	chr7_152645907_-	-1435.90	-1435.60	-1504.80
CAediting_613708	ENST00000495707.1	chr7_152645908_-	-1438.90	-1435.60	-1504.80
CAediting_613709	ENST00000495707.1	chr7_152645912_-	-1434.70	-1435.60	-1504.80
CAediting_613710	ENST00000495707.1	chr7_152645914_-	-1435.70	-1435.60	-1504.80
CAediting_613711	ENST00000495707.1	chr7_152645920_-	-1436.00	-1435.60	-1504.80
CAediting_613712	ENST00000495707.1	chr7_152646544_-	-1434.70	-1435.60	-1504.80
CAediting_613713	ENST00000495707.1	chr7_152646549_-	-1442.50	-1435.60	-1504.80
CAediting_613714	ENST00000495707.1	chr7_152646566_-	-1434.70	-1435.60	-1504.80
CAediting_613715	ENST00000495707.1	chr7_152646569_-	-1434.80	-1435.60	-1504.80
CAediting_613716	ENST00000495707.1	chr7_152646573_-	-1435.60	-1435.60	-1504.80
CAediting_613717	ENST00000495707.1	chr7_152646574_-	-1435.10	-1435.60	-1504.80
CAediting_613718	ENST00000495707.1	chr7_152646583_-	-1435.10	-1435.60	-1504.80
CAediting_613719	ENST00000495707.1	chr7_152646588_-	-1440.30	-1435.60	-1504.80
CAediting_613720	ENST00000495707.1	chr7_152646592_-	-1434.70	-1435.60	-1504.80
CAediting_613721	ENST00000495707.1	chr7_152646598_-	-1434.70	-1435.60	-1504.80
CAediting_613722	ENST00000495707.1	chr7_152646601_-	-1439.50	-1435.60	-1504.80
CAediting_613723	ENST00000495707.1	chr7_152646605_-	-1435.60	-1435.60	-1504.80
CAediting_613724	ENST00000495707.1	chr7_152646609_-	-1434.90	-1435.60	-1504.80
CAediting_613725	ENST00000495707.1	chr7_152646641_-	-1435.30	-1435.60	-1504.80
CAediting_613726	ENST00000495707.1	chr7_152646645_-	-1435.70	-1435.60	-1504.80
CAediting_613727	ENST00000495707.1	chr7_152646646_-	-1435.70	-1435.60	-1504.80
CAediting_613728	ENST00000495707.1	chr7_152646649_-	-1435.60	-1435.60	-1504.80
CAediting_613729	ENST00000495707.1	chr7_152646651_-	-1435.60	-1435.60	-1504.80
CAediting_613730	ENST00000495707.1	chr7_152646655_-	-1435.70	-1435.60	-1504.80
CAediting_613731	ENST00000495707.1	chr7_152646656_-	-1435.70	-1435.60	-1504.80
CAediting_613732	ENST00000495707.1	chr7_152646659_-	-1435.60	-1435.60	-1504.80
CAediting_613733	ENST00000495707.1	chr7_152646665_-	-1441.40	-1435.60	-1504.80
CAediting_613734	ENST00000495707.1	chr7_152646670_-	-1435.60	-1435.60	-1504.80
CAediting_613735	ENST00000495707.1	chr7_152646680_-	-1435.60	-1435.60	-1504.80
CAediting_613736	ENST00000495707.1	chr7_152646693_-	-1435.00	-1435.60	-1504.80
CAediting_613737	ENST00000495707.1	chr7_152646695_-	-1435.50	-1435.60	-1504.80
CAediting_613738	ENST00000495707.1	chr7_152646696_-	-1441.60	-1435.60	-1504.80
CAediting_613739	ENST00000495707.1	chr7_152646704_-	-1434.90	-1435.60	-1504.80
CAediting_613740	ENST00000495707.1	chr7_152646727_-	-1434.70	-1435.60	-1504.80
CAediting_613741	ENST00000495707.1	chr7_152646733_-	-1434.70	-1435.60	-1504.80
CAediting_613742	ENST00000495707.1	chr7_152646741_-	-1435.20	-1435.60	-1504.80
CAediting_613743	ENST00000495707.1	chr7_152646744_-	-1435.30	-1435.60	-1504.80
CAediting_613744	ENST00000495707.1	chr7_152646749_-	-1435.10	-1435.60	-1504.80
CAediting_613745	ENST00000495707.1	chr7_152646758_-	-1436.90	-1435.60	-1504.80
CAediting_613746	ENST00000495707.1	chr7_152648156_-	-1435.30	-1435.60	-1504.80
CAediting_613747	ENST00000495707.1	chr7_152648162_-	-1435.30	-1435.60	-1504.80
CAediting_613748	ENST00000495707.1	chr7_152648163_-	-1435.70	-1435.60	-1504.80
CAediting_613749	ENST00000495707.1	chr7_152648189_-	-1439.90	-1435.60	-1504.80
CAediting_613750	ENST00000495707.1	chr7_152648190_-	-1439.20	-1435.60	-1504.80
CAediting_613751	ENST00000495707.1	chr7_152648224_-	-1441.40	-1435.60	-1504.80
CAediting_613752	ENST00000495707.1	chr7_152648227_-	-1435.20	-1435.60	-1504.80
CAediting_613753	ENST00000495707.1	chr7_152648237_-	-1435.40	-1435.60	-1504.80
CAediting_613754	ENST00000495707.1	chr7_152648239_-	-1434.70	-1435.60	-1504.80
CAediting_613755	ENST00000495707.1	chr7_152648243_-	-1435.60	-1435.60	-1504.80
CAediting_613756	ENST00000495707.1	chr7_152648244_-	-1435.70	-1435.60	-1504.80
CAediting_613757	ENST00000495707.1	chr7_152648258_-	-1435.60	-1435.60	-1504.80
CAediting_613758	ENST00000495707.1	chr7_152648259_-	-1435.70	-1435.60	-1504.80
CAediting_613759	ENST00000495707.1	chr7_152648272_-	-1435.20	-1435.60	-1504.80
CAediting_613760	ENST00000495707.1	chr7_152648279_-	-1435.20	-1435.60	-1504.80
CAediting_613761	ENST00000495707.1	chr7_152648283_-	-1434.90	-1435.60	-1504.80
CAediting_613762	ENST00000495707.1	chr7_152648295_-	-1435.30	-1435.60	-1504.80
CAediting_613763	ENST00000495707.1	chr7_152648307_-	-1441.80	-1435.60	-1504.80
CAediting_613764	ENST00000495707.1	chr7_152648312_-	-1439.50	-1435.60	-1504.80
CAediting_613765	ENST00000495707.1	chr7_152648320_-	-1435.10	-1435.60	-1504.80
CAediting_613766	ENST00000495707.1	chr7_152648324_-	-1435.60	-1435.60	-1504.80
CAediting_613767	ENST00000495707.1	chr7_152648345_-	-1434.80	-1435.60	-1504.80
CAediting_613768	ENST00000495707.1	chr7_152648361_-	-1441.60	-1435.60	-1504.80
CAediting_613769	ENST00000495707.1	chr7_152648363_-	-1441.00	-1435.60	-1504.80
CAediting_613770	ENST00000495707.1	chr7_152648369_-	-1436.90	-1435.60	-1504.80
CAediting_613771	ENST00000495707.1	chr7_152648396_-	-1437.20	-1435.60	-1504.80
CAediting_613712	ENST00000359321.1	chr7_152646544_-	-1017.50	-1018.40	-1064.90
CAediting_613713	ENST00000359321.1	chr7_152646549_-	-1025.30	-1018.40	-1064.90
CAediting_613714	ENST00000359321.1	chr7_152646566_-	-1017.50	-1018.40	-1064.90
CAediting_613715	ENST00000359321.1	chr7_152646569_-	-1017.60	-1018.40	-1064.90
CAediting_613716	ENST00000359321.1	chr7_152646573_-	-1018.40	-1018.40	-1064.90
CAediting_613717	ENST00000359321.1	chr7_152646574_-	-1017.90	-1018.40	-1064.90
CAediting_613718	ENST00000359321.1	chr7_152646583_-	-1017.90	-1018.40	-1064.90
CAediting_613719	ENST00000359321.1	chr7_152646588_-	-1023.10	-1018.40	-1064.90
CAediting_613720	ENST00000359321.1	chr7_152646592_-	-1017.50	-1018.40	-1064.90
CAediting_613721	ENST00000359321.1	chr7_152646598_-	-1017.50	-1018.40	-1064.90
CAediting_613722	ENST00000359321.1	chr7_152646601_-	-1022.30	-1018.40	-1064.90
CAediting_613723	ENST00000359321.1	chr7_152646605_-	-1018.40	-1018.40	-1064.90
CAediting_613724	ENST00000359321.1	chr7_152646609_-	-1017.70	-1018.40	-1064.90
CAediting_613725	ENST00000359321.1	chr7_152646641_-	-1018.10	-1018.40	-1064.90
CAediting_613726	ENST00000359321.1	chr7_152646645_-	-1018.50	-1018.40	-1064.90
CAediting_613727	ENST00000359321.1	chr7_152646646_-	-1018.50	-1018.40	-1064.90
CAediting_613728	ENST00000359321.1	chr7_152646649_-	-1018.40	-1018.40	-1064.90
CAediting_613729	ENST00000359321.1	chr7_152646651_-	-1018.40	-1018.40	-1064.90
CAediting_613730	ENST00000359321.1	chr7_152646655_-	-1018.50	-1018.40	-1064.90
CAediting_613731	ENST00000359321.1	chr7_152646656_-	-1018.50	-1018.40	-1064.90
CAediting_613732	ENST00000359321.1	chr7_152646659_-	-1018.40	-1018.40	-1064.90
CAediting_613733	ENST00000359321.1	chr7_152646665_-	-1024.20	-1018.40	-1064.90
CAediting_613734	ENST00000359321.1	chr7_152646670_-	-1018.40	-1018.40	-1064.90
CAediting_613735	ENST00000359321.1	chr7_152646680_-	-1018.40	-1018.40	-1064.90
CAediting_613736	ENST00000359321.1	chr7_152646693_-	-1017.80	-1018.40	-1064.90
CAediting_613737	ENST00000359321.1	chr7_152646695_-	-1018.30	-1018.40	-1064.90
CAediting_613738	ENST00000359321.1	chr7_152646696_-	-1024.40	-1018.40	-1064.90
CAediting_613739	ENST00000359321.1	chr7_152646704_-	-1017.70	-1018.40	-1064.90
CAediting_613740	ENST00000359321.1	chr7_152646727_-	-1017.50	-1018.40	-1064.90
CAediting_613741	ENST00000359321.1	chr7_152646733_-	-1017.50	-1018.40	-1064.90
CAediting_613742	ENST00000359321.1	chr7_152646741_-	-1018.00	-1018.40	-1064.90
CAediting_613743	ENST00000359321.1	chr7_152646744_-	-1018.10	-1018.40	-1064.90
CAediting_613744	ENST00000359321.1	chr7_152646749_-	-1017.90	-1018.40	-1064.90
CAediting_613745	ENST00000359321.1	chr7_152646758_-	-1019.70	-1018.40	-1064.90
CAediting_613746	ENST00000359321.1	chr7_152648156_-	-1018.10	-1018.40	-1064.90
CAediting_613747	ENST00000359321.1	chr7_152648162_-	-1018.10	-1018.40	-1064.90
CAediting_613748	ENST00000359321.1	chr7_152648163_-	-1018.50	-1018.40	-1064.90
CAediting_613749	ENST00000359321.1	chr7_152648189_-	-1022.70	-1018.40	-1064.90
CAediting_613750	ENST00000359321.1	chr7_152648190_-	-1022.00	-1018.40	-1064.90
CAediting_613751	ENST00000359321.1	chr7_152648224_-	-1024.20	-1018.40	-1064.90
CAediting_613752	ENST00000359321.1	chr7_152648227_-	-1018.00	-1018.40	-1064.90
CAediting_613753	ENST00000359321.1	chr7_152648237_-	-1018.20	-1018.40	-1064.90
CAediting_613754	ENST00000359321.1	chr7_152648239_-	-1017.50	-1018.40	-1064.90
CAediting_613755	ENST00000359321.1	chr7_152648243_-	-1018.40	-1018.40	-1064.90
CAediting_613756	ENST00000359321.1	chr7_152648244_-	-1018.50	-1018.40	-1064.90
CAediting_613757	ENST00000359321.1	chr7_152648258_-	-1018.40	-1018.40	-1064.90
CAediting_613758	ENST00000359321.1	chr7_152648259_-	-1018.50	-1018.40	-1064.90
CAediting_613759	ENST00000359321.1	chr7_152648272_-	-1018.00	-1018.40	-1064.90
CAediting_613760	ENST00000359321.1	chr7_152648279_-	-1018.00	-1018.40	-1064.90
CAediting_613761	ENST00000359321.1	chr7_152648283_-	-1017.70	-1018.40	-1064.90
CAediting_613762	ENST00000359321.1	chr7_152648295_-	-1018.10	-1018.40	-1064.90
CAediting_613763	ENST00000359321.1	chr7_152648307_-	-1024.60	-1018.40	-1064.90
CAediting_613764	ENST00000359321.1	chr7_152648312_-	-1022.30	-1018.40	-1064.90
CAediting_613765	ENST00000359321.1	chr7_152648320_-	-1017.90	-1018.40	-1064.90
CAediting_613766	ENST00000359321.1	chr7_152648324_-	-1018.40	-1018.40	-1064.90
CAediting_613767	ENST00000359321.1	chr7_152648345_-	-1017.60	-1018.40	-1064.90
CAediting_613768	ENST00000359321.1	chr7_152648361_-	-1024.40	-1018.40	-1064.90
CAediting_613769	ENST00000359321.1	chr7_152648363_-	-1023.80	-1018.40	-1064.90
CAediting_613770	ENST00000359321.1	chr7_152648369_-	-1017.60	-1018.40	-1064.90
CAediting_613771	ENST00000359321.1	chr7_152648396_-	-1023.00	-1018.40	-1064.90

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Relation with ADAR for XRCC2

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_613682	chr7_152645359_-	3.53597829837014e-05	0.279366798366744	.	.	.	.
LUSC	CAediting_613682	chr7_152645359_-	0.000725454179213936	0.374691022369814	.	.	.	.
BRCA	CAediting_613683	chr7_152645360_-	7.01262413291137e-06	0.241318038211578	.	.	.	.
CESC	CAediting_613683	chr7_152645360_-	0.00749100437946893	0.263338915465165	.	.	.	.
LUAD	CAediting_613683	chr7_152645360_-	0.000950661817744252	0.346271299358618	.	.	.	.
LUSC	CAediting_613683	chr7_152645360_-	0.00123395025807671	0.241641798263822	.	.	.	.
OV	CAediting_613683	chr7_152645360_-	0.031522676413207	0.179935272191943	.	.	.	.
BLCA	CAediting_613700	chr7_152645818_-	3.28782924639239e-08	0.456704656295898	.	.	.	.
BRCA	CAediting_613700	chr7_152645818_-	3.60620663576071e-16	0.403682046053094	.	.	.	.
CESC	CAediting_613700	chr7_152645818_-	4.01191920769778e-07	0.384571832139575	.	.	0.0264435267634103	0.173866969336762
LUAD	CAediting_613700	chr7_152645818_-	0.00233907976511834	0.282331028452454	.	.	.	.
COAD	CAediting_613700	chr7_152645818_-	0.000132084643108277	0.351932749299449	.	.	.	.
LUSC	CAediting_613700	chr7_152645818_-	7.53947289173398e-17	0.457187113467763	.	.	.	.
GBM	CAediting_613700	chr7_152645818_-	0.0250240087629639	0.280018061086384	.	.	.	.
STAD	CAediting_613700	chr7_152645818_-	0.0217270081474088	0.182501792197994	.	.	.	.
UCEC	CAediting_613700	chr7_152645818_-	3.66618693131298e-06	0.430593160377409	.	.	.	.
OV	CAediting_613700	chr7_152645818_-	2.64781414833542e-05	0.278608089153503	.	.	.	.
SKCM	CAediting_613700	chr7_152645818_-	6.91272102714833e-07	0.367815229068655	.	.	.	.
SARC	CAediting_613700	chr7_152645818_-	0.000432778529662943	0.466306987935091	.	.	.	.
TGCT	CAediting_613700	chr7_152645818_-	1.02474157963515e-15	0.629616829441763	.	.	.	.
OV	CAediting_613705	chr7_152645864_-	0.0190775069365514	0.209428313844003	.	.	.	.
TGCT	CAediting_613705	chr7_152645864_-	0.0273014848460797	0.282657844690316	.	.	.	.
BLCA	CAediting_613707	chr7_152645907_-	0.00878472944821676	0.276231761844059	.	.	.	.
BRCA	CAediting_613707	chr7_152645907_-	5.66995260988762e-11	0.379222493842859	.	.	.	.
CESC	CAediting_613707	chr7_152645907_-	0.00154446898980265	0.295772058026997	.	.	.	.
LUAD	CAediting_613707	chr7_152645907_-	0.00194628472098293	0.333324203666172	.	.	.	.
LUSC	CAediting_613707	chr7_152645907_-	4.88040410523223e-09	0.389996558122442	.	.	.	.
HNSC	CAediting_613707	chr7_152645907_-	0.00478091768007211	0.326747721857689	.	.	.	.
UCEC	CAediting_613707	chr7_152645907_-	4.71333750682428e-05	0.528682663601542	.	.	.	.
LAML	CAediting_613707	chr7_152645907_-	.	.	.	.	0.00352843834931318	0.386840475710514
OV	CAediting_613707	chr7_152645907_-	3.02052737362704e-05	0.308943486637751	.	.	.	.
SKCM	CAediting_613707	chr7_152645907_-	0.00241093164130429	0.295865686134339	.	.	.	.
TGCT	CAediting_613707	chr7_152645907_-	1.48085816316185e-09	0.576439376880038	.	.	.	.
BRCA	CAediting_613710	chr7_152645914_-	8.63907393472051e-06	0.252870200314071	.	.	.	.
CESC	CAediting_613710	chr7_152645914_-	1.57967697497848e-07	0.428493360240809	.	.	.	.
COAD	CAediting_613710	chr7_152645914_-	0.021233123648794	0.234908682248251	.	.	.	.
LUSC	CAediting_613710	chr7_152645914_-	2.29542202686008e-07	0.325820684856012	.	.	.	.
HNSC	CAediting_613710	chr7_152645914_-	0.000824411718186573	0.332444556715257	.	.	.	.
UCEC	CAediting_613710	chr7_152645914_-	0.0107494001889825	0.329787316439132	.	.	.	.
OV	CAediting_613710	chr7_152645914_-	1.86091841054538e-07	0.371929260587623	.	.	.	.
SKCM	CAediting_613710	chr7_152645914_-	0.0495558853853222	0.176751460437037	.	.	.	.
TGCT	CAediting_613710	chr7_152645914_-	8.35370519343072e-09	0.523751925839996	.	.	.	.
BLCA	CAediting_613743	chr7_152646744_-	0.00906115021500436	0.318895355981587	.	.	.	.
CESC	CAediting_613743	chr7_152646744_-	0.00906479034742619	0.314226818285503	.	.	.	.
COAD	CAediting_613743	chr7_152646744_-	.	.	0.00709982321567034	0.346948835615408	.	.
HNSC	CAediting_613743	chr7_152646744_-	.	.	3.35650260748766e-05	0.471239751199278	.	.

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Relation with cancer stages for XRCC2

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BLCA	pathologic_stage	CAediting_613683	chr7_152645360_-	0.0438321616710521	0.220518901730593
BRCA	pathologic_stage	CAediting_613743	chr7_152646744_-	0.0153435735913607	0.161091845520997
CESC	clinical_stage	CAediting_613710	chr7_152645914_-	0.00284327806945807	-0.254950893995879
ESCA	clinical_stage	CAediting_613700	chr7_152645818_-	0.0338996280913459	-0.313459647863907
HNSC	clinical_stage	CAediting_613700	chr7_152645818_-	0.0423530901078223	0.175647949553061
LUSC	pathologic_stage	CAediting_613677	chr7_152645307_-	0.000569083315795731	-0.453738202383383
OV	clinical_stage	CAediting_613725	chr7_152646641_-	0.03759138498404	-0.252726509296294
SKCM	pathologic_stage	CAediting_613710	chr7_152645914_-	0.00314346422025332	0.28695154078472
STAD	pathologic_stage	CAediting_613716	chr7_152646573_-	0.0245316508869315	-0.257838528997022
TGCT	clinical_stage	CAediting_613700	chr7_152645818_-	0.0443427140228893	-0.239409231290128
TGCT	clinical_stage	CAediting_613710	chr7_152645914_-	0.0187032433315849	-0.310585125932763
TGCT	pathologic_stage	CAediting_613700	chr7_152645818_-	0.00252400537729332	-0.350720758979851
TGCT	pathologic_stage	CAediting_613710	chr7_152645914_-	0.000758846671098783	-0.433368102067981

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Relation with survival for XRCC2

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LUAD	CAediting_613743	chr7_152646744_-	0.0425167889298278	0.017799	275.822
ESCA	CAediting_613751	chr7_152648224_-	0.00616964782213247	0.0461834	13849.1

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RelatedDrugs for XRCC2

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for XRCC2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
XRCC2	C0346153	Breast Cancer, Familial	4	CLINGEN;ORPHANET
XRCC2	C0015625	Fanconi Anemia	3	GENOMICS_ENGLAND;ORPHANET
XRCC2	C0006142	Malignant neoplasm of breast	1	CTD_human
XRCC2	C0023465	Acute monocytic leukemia	1	GENOMICS_ENGLAND
XRCC2	C0023467	Leukemia, Myelocytic, Acute	1	GENOMICS_ENGLAND
XRCC2	C0265219	Miller Dieker syndrome	1	GENOMICS_ENGLAND
XRCC2	C0678222	Breast Carcinoma	1	CTD_human
XRCC2	C1257931	Mammary Neoplasms, Human	1	CTD_human
XRCC2	C1458155	Mammary Neoplasms	1	CTD_human
XRCC2	C3463824	MYELODYSPLASTIC SYNDROME	1	GENOMICS_ENGLAND
XRCC2	C4310651	FANCONI ANEMIA, COMPLEMENTATION GROUP U	1	CTD_human;GENOMICS_ENGLAND
XRCC2	C4704874	Mammary Carcinoma, Human	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene