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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: NELFA (CAeditome ID:7469)

Gene summary for NELFA

check button Gene summary
Gene informationGene symbol

NELFA

Gene ID

7469

Gene namenegative elongation factor complex member A
SynonymsNELF-A|P/OKcl.15|WHSC2
Cytomap

4p16.3

Type of geneprotein-coding
Descriptionnegative elongation factor Awolf-Hirschhorn syndrome candidate 2 protein
Modification date20210518
UniProtAcc

Q9H3P2

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
NELFA

GO:0005654

Negative elongation factor A

0000052

NELFA

GO:0005829

Negative elongation factor A

0000052

NELFA

GO:0016604

Negative elongation factor A

0000052

NELFA

GO:0032021

Negative elongation factor A

12612062


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RNA A-to-I events for NELFA

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000185049.11

check button RNA A-to-I editing events in Cancer.
CAediting_345870(1993526, -), CAediting_345871(1993866, -), CAediting_345872(1993868, -), CAediting_345873(1993877, -), CAediting_345874(1993890, -), CAediting_345875(1993891, -), CAediting_345876(1993898, -), CAediting_345877(1993916, -), CAediting_345878(1993919, -), CAediting_345879(1993922, -), CAediting_345880(1993933, -), CAediting_345881(1994143, -), CAediting_345882(1994203, -), CAediting_345883(1994218, -), CAediting_345884(1994224, -), CAediting_345885(1994232, -), CAediting_345886(1994786, -), CAediting_345887(1994808, -), CAediting_345888(1994835, -), CAediting_345889(1996687, -), CAediting_345890(1996997, -), CAediting_345891(1996998, -), CAediting_345892(1997056, -), CAediting_345893(2002137, -), CAediting_345894(2003890, -), CAediting_345895(2003894, -), CAediting_345896(2003896, -), CAediting_345897(2003908, -), CAediting_345898(2003909, -), CAediting_345899(2003927, -), CAediting_345900(2003939, -), CAediting_345901(2003959, -), CAediting_345902(2003994, -), CAediting_345903(2004037, -), CAediting_345904(2004047, -), CAediting_345905(2004059, -), CAediting_345906(2004076, -), CAediting_345907(2004077, -), CAediting_345908(2004102, -), CAediting_345909(2004133, -), CAediting_345910(2004155, -), CAediting_345911(2004517, -), CAediting_345912(2004520, -), CAediting_345913(2004556, -), CAediting_345914(2004598, -), CAediting_345915(2004634, -), CAediting_345916(2004636, -), CAediting_345917(2004652, -), CAediting_345918(2004658, -), CAediting_345919(2004663, -), CAediting_345920(2004681, -), CAediting_345921(2004739, -), CAediting_345922(2004752, -), CAediting_345923(2004760, -), CAediting_345924(2004774, -), CAediting_345925(2005080, -), CAediting_345926(2005081, -), CAediting_345927(2005094, -), CAediting_345928(2005592, -), CAediting_345929(2005597, -), CAediting_345930(2005610, -), CAediting_345931(2005678, -), CAediting_345932(2005691, -), CAediting_345933(2006558, -), CAediting_345934(2006717, -), CAediting_345935(2006743, -), CAediting_345936(2007023, -), CAediting_345937(2007101, -), CAediting_345938(2007150, -), CAediting_345939(2007185, -), CAediting_345940(2009856, -), CAediting_345941(2010492, -), CAediting_345942(2010499, -), CAediting_345943(2010502, -), CAediting_345944(2011199, -), CAediting_345945(2011200, -), CAediting_345946(2011206, -), CAediting_345947(2011212, -), CAediting_345948(2011246, -), CAediting_345949(2011256, -), CAediting_345950(2011259, -), CAediting_345951(2011268, -), CAediting_345952(2011281, -), CAediting_345953(2011286, -), CAediting_345954(2011305, -), CAediting_345955(2011306, -), CAediting_345956(2011321, -), CAediting_345957(2011858, -), CAediting_345958(2011862, -), CAediting_345959(2011868, -), CAediting_345960(2011871, -), CAediting_345961(2011881, -), CAediting_345962(2011894, -), CAediting_345963(2011898, -), CAediting_345964(2011904, -), CAediting_345965(2011926, -), CAediting_345966(2011936, -), CAediting_345967(2011959, -), CAediting_345968(2011969, -), CAediting_345969(2012003, -), CAediting_345970(2012022, -), CAediting_345971(2012039, -), CAediting_345972(2012327, -), CAediting_345973(2012332, -), CAediting_345974(2012360, -), CAediting_345975(2012385, -), CAediting_345976(2012397, -), CAediting_345977(2012472, -), CAediting_345978(2013003, -), CAediting_345979(2013597, -), CAediting_345980(2014177, -), CAediting_345981(2014364, -), CAediting_345982(2017163, -), CAediting_345983(2019446, -), CAediting_345984(2019460, -), CAediting_345985(2020705, -), CAediting_345986(2020982, -), CAediting_345987(2021024, -), CAediting_345988(2021047, -), CAediting_345989(2021085, -), CAediting_345990(2021091, -), CAediting_345991(2021097, -), CAediting_345992(2021103, -), CAediting_345993(2021112, -), CAediting_345994(2021180, -), CAediting_345995(2021181, -), CAediting_345996(2021182, -), CAediting_345997(2021190, -), CAediting_345998(2037366, -), CAediting_345999(2037374, -), CAediting_346000(2039196, -), CAediting_346001(2040245, -),

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RNA editing positional annotations for NELFA using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_345870chr4_1993526_-intronic
CAediting_345871chr4_1993866_-intronic
CAediting_345872chr4_1993868_-intronic
CAediting_345873chr4_1993877_-intronic
CAediting_345874chr4_1993890_-intronic
CAediting_345875chr4_1993891_-intronic
CAediting_345876chr4_1993898_-intronic
CAediting_345877chr4_1993916_-intronic
CAediting_345878chr4_1993919_-intronic
CAediting_345879chr4_1993922_-intronic
CAediting_345880chr4_1993933_-intronic
CAediting_345881chr4_1994143_-intronic
CAediting_345882chr4_1994203_-intronic
CAediting_345883chr4_1994218_-intronic
CAediting_345884chr4_1994224_-intronic
CAediting_345885chr4_1994232_-intronic
CAediting_345886chr4_1994786_-intronic
CAediting_345887chr4_1994808_-intronic
CAediting_345888chr4_1994835_-intronic
CAediting_345889chr4_1996687_-intronic
CAediting_345890chr4_1996997_-intronic
CAediting_345891chr4_1996998_-intronic
CAediting_345892chr4_1997056_-intronic
CAediting_345893chr4_2002137_-intronic
CAediting_345894chr4_2003890_-UTR3
CAediting_345895chr4_2003894_-UTR3
CAediting_345896chr4_2003896_-UTR3
CAediting_345897chr4_2003908_-UTR3
CAediting_345898chr4_2003909_-UTR3
CAediting_345899chr4_2003927_-UTR3
CAediting_345900chr4_2003939_-UTR3
CAediting_345901chr4_2003959_-UTR3
CAediting_345902chr4_2003994_-UTR3
CAediting_345903chr4_2004037_-UTR3
CAediting_345904chr4_2004047_-UTR3
CAediting_345905chr4_2004059_-UTR3
CAediting_345906chr4_2004076_-UTR3
CAediting_345907chr4_2004077_-UTR3
CAediting_345908chr4_2004102_-UTR3
CAediting_345909chr4_2004133_-UTR3
CAediting_345910chr4_2004155_-intronic
CAediting_345911chr4_2004517_-intronic
CAediting_345912chr4_2004520_-intronic
CAediting_345913chr4_2004556_-intronic
CAediting_345914chr4_2004598_-intronic
CAediting_345915chr4_2004634_-intronic
CAediting_345916chr4_2004636_-intronic
CAediting_345917chr4_2004652_-intronic
CAediting_345918chr4_2004658_-intronic
CAediting_345919chr4_2004663_-intronic
CAediting_345920chr4_2004681_-intronic
CAediting_345921chr4_2004739_-intronic
CAediting_345922chr4_2004752_-intronic
CAediting_345923chr4_2004760_-intronic
CAediting_345924chr4_2004774_-intronic
CAediting_345925chr4_2005080_-intronic
CAediting_345926chr4_2005081_-intronic
CAediting_345927chr4_2005094_-intronic
CAediting_345928chr4_2005592_-intronic
CAediting_345929chr4_2005597_-intronic
CAediting_345930chr4_2005610_-intronic
CAediting_345931chr4_2005678_-intronic
CAediting_345932chr4_2005691_-intronic
CAediting_345933chr4_2006558_-intronic
CAediting_345934chr4_2006717_-intronic
CAediting_345935chr4_2006743_-intronic
CAediting_345936chr4_2007023_-UTR3
CAediting_345937chr4_2007101_-exonic
CAediting_345938chr4_2007150_-exonic
CAediting_345939chr4_2007185_-exonic
CAediting_345940chr4_2009856_-UTR5
CAediting_345941chr4_2010492_-intronic
CAediting_345942chr4_2010499_-intronic
CAediting_345943chr4_2010502_-intronic
CAediting_345944chr4_2011199_-intronic
CAediting_345945chr4_2011200_-intronic
CAediting_345946chr4_2011206_-intronic
CAediting_345947chr4_2011212_-intronic
CAediting_345948chr4_2011246_-intronic
CAediting_345949chr4_2011256_-intronic
CAediting_345950chr4_2011259_-intronic
CAediting_345951chr4_2011268_-intronic
CAediting_345952chr4_2011281_-intronic
CAediting_345953chr4_2011286_-intronic
CAediting_345954chr4_2011305_-intronic
CAediting_345955chr4_2011306_-intronic
CAediting_345956chr4_2011321_-intronic
CAediting_345957chr4_2011858_-intronic
CAediting_345958chr4_2011862_-intronic
CAediting_345959chr4_2011868_-intronic
CAediting_345960chr4_2011871_-intronic
CAediting_345961chr4_2011881_-intronic
CAediting_345962chr4_2011894_-intronic
CAediting_345963chr4_2011898_-intronic
CAediting_345964chr4_2011904_-intronic
CAediting_345965chr4_2011926_-intronic
CAediting_345966chr4_2011936_-intronic
CAediting_345967chr4_2011959_-intronic
CAediting_345968chr4_2011969_-intronic
CAediting_345969chr4_2012003_-intronic
CAediting_345970chr4_2012022_-intronic
CAediting_345971chr4_2012039_-intronic
CAediting_345972chr4_2012327_-intronic
CAediting_345973chr4_2012332_-intronic
CAediting_345974chr4_2012360_-intronic
CAediting_345975chr4_2012385_-intronic
CAediting_345976chr4_2012397_-intronic
CAediting_345977chr4_2012472_-intronic
CAediting_345978chr4_2013003_-intronic
CAediting_345979chr4_2013597_-intronic
CAediting_345980chr4_2014177_-intronic
CAediting_345981chr4_2014364_-intronic
CAediting_345982chr4_2017163_-intronic
CAediting_345983chr4_2019446_-intronic
CAediting_345984chr4_2019460_-intronic
CAediting_345985chr4_2020705_-intronic
CAediting_345986chr4_2020982_-intronic
CAediting_345987chr4_2021024_-intronic
CAediting_345988chr4_2021047_-intronic
CAediting_345989chr4_2021085_-intronic
CAediting_345990chr4_2021091_-intronic
CAediting_345991chr4_2021097_-intronic
CAediting_345992chr4_2021103_-intronic
CAediting_345993chr4_2021112_-intronic
CAediting_345994chr4_2021180_-intronic
CAediting_345995chr4_2021181_-intronic
CAediting_345996chr4_2021182_-intronic
CAediting_345997chr4_2021190_-intronic
CAediting_345998chr4_2037366_-intronic
CAediting_345999chr4_2037374_-intronic
CAediting_346000chr4_2039196_-intronic
CAediting_346001chr4_2040245_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_345870chr4_1993526_-SINEAluAluSp
CAediting_345871chr4_1993866_-SINEAluAluSq2
CAediting_345872chr4_1993868_-SINEAluAluSq2
CAediting_345873chr4_1993877_-SINEAluAluSq2
CAediting_345874chr4_1993890_-SINEAluAluSq2
CAediting_345875chr4_1993891_-SINEAluAluSq2
CAediting_345876chr4_1993898_-SINEAluAluSq2
CAediting_345877chr4_1993916_-SINEAluAluSq2
CAediting_345878chr4_1993919_-SINEAluAluSq2
CAediting_345879chr4_1993922_-SINEAluAluSq2
CAediting_345880chr4_1993933_-SINEAluAluSq2
CAediting_345881chr4_1994143_-SINEAluAluJo
CAediting_345882chr4_1994203_-SINEAluAluJo
CAediting_345883chr4_1994218_-SINEAluAluJo
CAediting_345884chr4_1994224_-SINEAluAluJo
CAediting_345885chr4_1994232_-SINEAluAluJo
CAediting_345886chr4_1994786_-SINEAluAluY
CAediting_345887chr4_1994808_-SINEAluAluY
CAediting_345888chr4_1994835_-SINEAluAluY
CAediting_345889chr4_1996687_-SINEAluAluSz6
CAediting_345890chr4_1996997_-SINEAluAluJr4
CAediting_345891chr4_1996998_-SINEAluAluJr4
CAediting_345892chr4_1997056_-SINEAluAluJr4
CAediting_345893chr4_2002137_-SINEAluAluY
CAediting_345894chr4_2003890_-SINEAluAluSc
CAediting_345895chr4_2003894_-SINEAluAluSc
CAediting_345896chr4_2003896_-SINEAluAluSc
CAediting_345897chr4_2003908_-SINEAluAluSc
CAediting_345898chr4_2003909_-SINEAluAluSc
CAediting_345899chr4_2003927_-SINEAluAluSc
CAediting_345900chr4_2003939_-SINEAluAluSc
CAediting_345901chr4_2003959_-SINEAluAluSc
CAediting_345902chr4_2003994_-SINEAluAluSc
CAediting_345903chr4_2004037_-SINEAluAluSc
CAediting_345904chr4_2004047_-SINEAluAluSc
CAediting_345905chr4_2004059_-SINEAluAluSc
CAediting_345906chr4_2004076_-SINEAluAluSc
CAediting_345907chr4_2004077_-SINEAluAluSc
CAediting_345908chr4_2004102_-SINEAluAluSc
CAediting_345909chr4_2004133_-SINEAluAluSc
CAediting_345910chr4_2004155_-SINEAluAluSc
CAediting_345911chr4_2004517_-SINEAluAluJb
CAediting_345912chr4_2004520_-SINEAluAluJb
CAediting_345913chr4_2004556_-SINEAluAluJb
CAediting_345914chr4_2004598_-SINEAluAluJb
CAediting_345915chr4_2004634_-SINEAluAluJb
CAediting_345916chr4_2004636_-SINEAluAluJb
CAediting_345917chr4_2004652_-SINEAluAluJb
CAediting_345918chr4_2004658_-SINEAluAluJb
CAediting_345919chr4_2004663_-SINEAluAluJb
CAediting_345920chr4_2004681_-SINEAluAluJb
CAediting_345921chr4_2004739_-SINEAluAluJb
CAediting_345922chr4_2004752_-SINEAluAluJb
CAediting_345923chr4_2004760_-SINEAluAluJb
CAediting_345924chr4_2004774_-SINEAluAluJb
CAediting_345925chr4_2005080_-SINEAluAluY
CAediting_345926chr4_2005081_-SINEAluAluY
CAediting_345927chr4_2005094_-SINEAluAluY
CAediting_345928chr4_2005592_-SINEAluAluSx
CAediting_345929chr4_2005597_-SINEAluAluSx
CAediting_345930chr4_2005610_-SINEAluAluSx
CAediting_345931chr4_2005678_-SINEAluAluSx
CAediting_345932chr4_2005691_-SINEAluAluSx
CAediting_345933chr4_2006558_-SINEAluAluJr
CAediting_345934chr4_2006717_-SINEAluAluJr
CAediting_345935chr4_2006743_-SINEAluAluJr
CAediting_345936chr4_2007023_-SINEAluAluJb
CAediting_345937chr4_2007101_-SINEAluAluJb
CAediting_345938chr4_2007150_-SINEAluAluJb
CAediting_345939chr4_2007185_-SINEAluAluJb
CAediting_345940chr4_2009856_-SINEAluAluJo
CAediting_345941chr4_2010492_-SINEAluAluSp
CAediting_345942chr4_2010499_-SINEAluAluSp
CAediting_345943chr4_2010502_-SINEAluAluSp
CAediting_345944chr4_2011199_-SINEAluAluSx
CAediting_345945chr4_2011200_-SINEAluAluSx
CAediting_345946chr4_2011206_-SINEAluAluSx
CAediting_345947chr4_2011212_-SINEAluAluSx
CAediting_345948chr4_2011246_-SINEAluAluSx
CAediting_345949chr4_2011256_-SINEAluAluSx
CAediting_345950chr4_2011259_-SINEAluAluSx
CAediting_345951chr4_2011268_-SINEAluAluSx
CAediting_345952chr4_2011281_-SINEAluAluSx
CAediting_345953chr4_2011286_-SINEAluAluSx
CAediting_345954chr4_2011305_-SINEAluAluSx
CAediting_345955chr4_2011306_-SINEAluAluSx
CAediting_345956chr4_2011321_-SINEAluAluSx
CAediting_345957chr4_2011858_-SINEAluAluSz
CAediting_345958chr4_2011862_-SINEAluAluSz
CAediting_345959chr4_2011868_-SINEAluAluSz
CAediting_345960chr4_2011871_-SINEAluAluSz
CAediting_345961chr4_2011881_-SINEAluAluSz
CAediting_345962chr4_2011894_-SINEAluAluSz
CAediting_345963chr4_2011898_-SINEAluAluSz
CAediting_345964chr4_2011904_-SINEAluAluSz
CAediting_345965chr4_2011926_-SINEAluAluSz
CAediting_345966chr4_2011936_-SINEAluAluSz
CAediting_345967chr4_2011959_-SINEAluAluSz
CAediting_345968chr4_2011969_-SINEAluAluSz
CAediting_345969chr4_2012003_-SINEAluAluSz
CAediting_345970chr4_2012022_-SINEAluAluSz
CAediting_345971chr4_2012039_-SINEAluAluSz
CAediting_345972chr4_2012327_-SINEAluAluJr
CAediting_345973chr4_2012332_-SINEAluAluJr
CAediting_345974chr4_2012360_-SINEAluAluJr
CAediting_345975chr4_2012385_-SINEAluAluJr
CAediting_345976chr4_2012397_-SINEAluAluJr
CAediting_345977chr4_2012472_-SINEAluAluJr
CAediting_345978chr4_2013003_-SINEAluAluSq2
CAediting_345979chr4_2013597_-SINEAluAluSx3
CAediting_345980chr4_2014177_-SINEAluAluSz6
CAediting_345981chr4_2014364_-SINEAluAluJr4
CAediting_345982chr4_2017163_-SINEAluAluY
CAediting_345983chr4_2019446_-SINEAluAluY
CAediting_345984chr4_2019460_-SINEAluAluY
CAediting_345985chr4_2020705_-SINEAluAluY
CAediting_345986chr4_2020982_-SINEAluAluSz
CAediting_345987chr4_2021024_-SINEAluAluSz
CAediting_345988chr4_2021047_-SINEAluAluSz
CAediting_345989chr4_2021085_-SINEAluAluSz
CAediting_345990chr4_2021091_-SINEAluAluSz
CAediting_345991chr4_2021097_-SINEAluAluSz
CAediting_345992chr4_2021103_-SINEAluAluSz
CAediting_345993chr4_2021112_-SINEAluAluSz
CAediting_345994chr4_2021180_-SINEAluAluSz
CAediting_345995chr4_2021181_-SINEAluAluSz
CAediting_345996chr4_2021182_-SINEAluAluSz
CAediting_345997chr4_2021190_-SINEAluAluSz
CAediting_345998chr4_2037366_-SINEAluAluSz6
CAediting_345999chr4_2037374_-SINEAluAluSz6
CAediting_346000chr4_2039196_-SINEAluAluSx1
CAediting_346001chr4_2040245_-SINEAluAluSx

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RNA A-to-I editing events in the alternative splicing sites for NELFA

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_345906chr4_2004076_-2004075:20040835SS0+5iAGGTTCAAG-12.66AGGTTCAGG-5.91
ESCAediting_345907chr4_2004077_-2004075:20040835SS0+4iAGGTTCAAG-12.66AGGTTCGAG-17.82
ESCAediting_345910chr4_2004155_-2004148:20041703SS0+5iTTTTCTTTTTTTTGAAACAGAGT8.77TTTTCTTTTTTTTGAGACAGAGT3.19

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000185049.11.NELFA.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000185049.11.NELFA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NELFA

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NELFA

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for NELFA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_345896chr4_2003896_-ENSG00000185049.11ENST00000458616hsa-miR-106a-3p200389420038996mer20038932003914141.00-21.13
CAediting_345897chr4_2003908_-ENSG00000185049.11ENST00000458616hsa-miR-3189-3p200390720039137mer-m820039062003929145.00-23.27
CAediting_345897chr4_2003908_-ENSG00000185049.11ENST00000458616hsa-miR-6813-3p200390620039127mer-m820039052003925140.00-12.88
CAediting_345898chr4_2003909_-ENSG00000185049.11ENST00000458616hsa-miR-326200390720039137mer-m820039062003925140.00-15.33
CAediting_345898chr4_2003909_-ENSG00000185049.11ENST00000458616hsa-miR-330-5p200390720039137mer-m820039062003927140.00-22.45
CAediting_345898chr4_2003909_-ENSG00000185049.11ENST00000458616hsa-miR-4314200390820039147mer-m820039072003924140.00-18.79
CAediting_345898chr4_2003909_-ENSG00000185049.11ENST00000458616hsa-miR-514a-5p200390620039127mer-m820039052003925154.00-19.31
CAediting_345898chr4_2003909_-ENSG00000185049.11ENST00000458616hsa-miR-514a-5p200390620039127mer-m820039052003925154.00-19.31
CAediting_345898chr4_2003909_-ENSG00000185049.11ENST00000458616hsa-miR-514a-5p200390620039127mer-m820039052003925154.00-19.31
CAediting_345899chr4_2003927_-ENSG00000185049.11ENST00000458616hsa-miR-3937200392320039297mer-m820039222003942148.00-20.51
CAediting_345900chr4_2003939_-ENSG00000185049.11ENST00000458616hsa-miR-3922-5p200393420039407mer-m820039332003956157.00-23.34
CAediting_345900chr4_2003939_-ENSG00000185049.11ENST00000458616hsa-miR-4753-5p200393520039417mer-m820039342003956163.00-25.27
CAediting_345903chr4_2004037_-ENSG00000185049.11ENST00000458616hsa-miR-3925-3p200403320040408mer-1a20040332004054165.00-25.30
CAediting_345904chr4_2004047_-ENSG00000185049.11ENST00000458616hsa-miR-4691-3p200404320040497mer-m820040422004069150.00-26.36
CAediting_345906chr4_2004076_-ENSG00000185049.11ENST00000458616hsa-miR-331-3p200407220040787mer-1a20040722004092140.00-22.73
CAediting_345906chr4_2004076_-ENSG00000185049.11ENST00000458616hsa-miR-345-3p200407420040807mer-m820040732004094155.00-25.81
CAediting_345906chr4_2004076_-ENSG00000185049.11ENST00000458616hsa-miR-4539200407620040816mer20040752004097143.00-23.54
CAediting_345909chr4_2004133_-ENSG00000185049.11ENST00000458616hsa-miR-3940-3p200412920041357mer-m820041282004148145.00-22.78

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000421397hsa-miR-4478200701920070257mer-m820070182007034154-22.92
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000421397hsa-miR-4649-3p200702220070287mer-m820070212007041144-15.67
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000421397hsa-miR-485-5p200701820070247mer-m820070172007039147-15.76
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000421397hsa-miR-7160-5p200702120070277mer-m820070202007038146-17.89
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000443203hsa-miR-4478200701920070257mer-m820070182007034154-22.92
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000443203hsa-miR-4649-3p200702220070287mer-m820070212007041144-15.67
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000443203hsa-miR-485-5p200701820070247mer-m820070172007039147-15.76
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000443203hsa-miR-7160-5p200702120070277mer-m820070202007038146-17.89
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000458616hsa-miR-4478200701920070257mer-m820070182007034154-22.92
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000458616hsa-miR-4649-3p200702220070287mer-m820070212007041144-15.67
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000458616hsa-miR-485-5p200701820070247mer-m820070172007039147-15.76
CAediting_345936chr4_2007023_-ENSG00000185049.11ENST00000458616hsa-miR-7160-5p200702120070277mer-m820070202007038146-17.89
CAediting_345899chr4_2003927_-ENSG00000185049.11ENST00000458616hsa-miR-12114200392420039307mer-m820039232003940147-27.08
CAediting_345901chr4_2003959_-ENSG00000185049.11ENST00000458616hsa-miR-3190-5p200395820039647mer-m820039572003975152-22.63
CAediting_345899chr4_2003927_-ENSG00000185049.11ENST00000458616hsa-miR-3665200392220039287mer-m820039212003938140-16.36
CAediting_345902chr4_2003994_-ENSG00000185049.11ENST00000458616hsa-miR-381-3p200399320039986mer20039922004013140-11.94
CAediting_345900chr4_2003939_-ENSG00000185049.11ENST00000458616hsa-miR-3974200393520039417mer-m820039342003956144-12.79
CAediting_345905chr4_2004059_-ENSG00000185049.11ENST00000458616hsa-miR-4478200405520040617mer-m820040542004069149-25.05
CAediting_345905chr4_2004059_-ENSG00000185049.11ENST00000458616hsa-miR-4649-3p200405820040647mer-m820040572004077147-20.55
CAediting_345901chr4_2003959_-ENSG00000185049.11ENST00000458616hsa-miR-548s200395920039657mer-m820039582003980149-13.99
CAediting_345903chr4_2004037_-ENSG00000185049.11ENST00000458616hsa-miR-554200403520040428mer-1a20040352004055149-17.29
CAediting_345904chr4_2004047_-ENSG00000185049.11ENST00000458616hsa-miR-5690200404320040497mer-m820040422004062145-16.75
CAediting_345906chr4_2004076_-ENSG00000185049.11ENST00000458616hsa-miR-623200407220040787mer-m820040712004097148-24.16
CAediting_345907chr4_2004077_-ENSG00000185049.11ENST00000458616hsa-miR-623200407220040787mer-m820040712004097148-24.16
CAediting_345894chr4_2003890_-ENSG00000185049.11ENST00000458616hsa-miR-6514-3p200389020038967mer-m820038892003909155-17.54
CAediting_345895chr4_2003894_-ENSG00000185049.11ENST00000458616hsa-miR-6514-3p200389020038967mer-m820038892003909155-17.54
CAediting_345894chr4_2003890_-ENSG00000185049.11ENST00000458616hsa-miR-6847-3p200388520038917mer-m820038842003906153-22.19
CAediting_345906chr4_2004076_-ENSG00000185049.11ENST00000458616hsa-miR-6866-3p200407120040777mer-m820040702004092149-16.48
CAediting_345905chr4_2004059_-ENSG00000185049.11ENST00000458616hsa-miR-7160-5p200405720040637mer-m820040562004076146-20.88
CAediting_345908chr4_2004102_-ENSG00000185049.11ENST00000458616hsa-miR-7855-5p200409920041057mer-m820040982004115143-17.74
CAediting_345898chr4_2003909_-ENSG00000185049.11ENST00000458616hsa-miR-887-5p200390820039158mer-1a20039082003929148-16.93

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000185049.11ENST00000542778hsa-miR-605-3p198295219829587mer-m819829511982972150-21.1
CAediting_748296chr10_51299626_+ENSG00000185049.11ENST00000416258hsa-miR-605-3p198295219829587mer-m819829511982972150-21.1
CAediting_748296chr10_51299626_+ENSG00000185049.11ENST00000333877hsa-miR-605-3p198488219848887mer-m819848811984901146-16.5
CAediting_748296chr10_51299626_+ENSG00000185049.11ENST00000333877hsa-miR-605-3p198295219829587mer-m819829511982972150-21.1
CAediting_1229415chr17_67471547_+ENSG00000185049.11ENST00000542778hsa-miR-548aa198326319832697mer-m819832621983284144-13.5
CAediting_1229415chr17_67471547_+ENSG00000185049.11ENST00000416258hsa-miR-548aa198326319832697mer-m819832621983284144-13.5
CAediting_1368054chr19_46709310_-ENSG00000185049.11ENST00000333877hsa-miR-320e198482219848287mer-m819848211984840146-21.74
CAediting_1054808chr15_66496985_-ENSG00000185049.11ENST00000333877hsa-miR-4512198390019839056mer19838841983907143-21.26
CAediting_1054808chr15_66496985_-ENSG00000185049.11ENST00000333877hsa-miR-4512198388519838917mer-m819838841983907143-21.26
CAediting_1229415chr17_67471547_+ENSG00000185049.11ENST00000333877hsa-miR-548aa198326319832697mer-m819832621983284144-13.5
CAediting_1229414chr17_67471546_+ENSG00000185049.11ENST00000421397hsa-miR-548aa200705620070627mer-m820070552007079140-12.81
CAediting_396018chr5_1062918_-ENSG00000185049.11ENST00000421397hsa-miR-4635200703920070457mer-m820070382007058162-20.74
CAediting_1229414chr17_67471546_+ENSG00000185049.11ENST00000443203hsa-miR-548aa200705620070627mer-m820070552007079140-12.81
CAediting_396018chr5_1062918_-ENSG00000185049.11ENST00000443203hsa-miR-4635200703920070457mer-m820070382007058162-20.74
CAediting_1368054chr19_46709310_-ENSG00000185049.11ENST00000443203hsa-miR-320e199168319916897mer-m819916821991698147-16.26
CAediting_1229414chr17_67471546_+ENSG00000185049.11ENST00000458616hsa-miR-548aa200705620070627mer-m820070552007079140-12.81
CAediting_396018chr5_1062918_-ENSG00000185049.11ENST00000458616hsa-miR-4635200703920070457mer-m820070382007058162-20.74
CAediting_468389chr6_31355314_-ENSG00000185049.11ENST00000333877hsa-miR-6891-5p198483719848437mer-m819848361984855151-22.82
CAediting_1524209chrX_134546392_-ENSG00000185049.11ENST00000333877hsa-miR-503-5p198488519848917mer-m819848841984910150-20.27
CAediting_1524209chrX_134546392_-ENSG00000185049.11ENST00000333877hsa-miR-503-5p198367519836817mer-m819836741983692159-23.39

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1368054chr19_46709310_-ENSG00000185049.11ENST00000542778hsa-miR-320e198325419832618mer-1a19832541983271140-12.31
CAediting_1368054chr19_46709310_-ENSG00000185049.11ENST00000416258hsa-miR-320e198325419832618mer-1a19832541983271140-12.31
CAediting_1368054chr19_46709310_-ENSG00000185049.11ENST00000333877hsa-miR-320e198325419832618mer-1a19832541983271140-12.31

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NELFA

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000382882.6protein_codingSoverviewSoverview
ENST00000421397.4nonsense_mediated_decaySoverviewSoverview
ENST00000443203.4nonsense_mediated_decaySoverviewSoverview
ENST00000458616.1nonsense_mediated_decaySoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_345940ENST00000382882.6chr4_2009856_--1360.00-1355.90-1360.00
CAediting_345936ENST00000421397.4chr4_2007023_--218.40-219.10-223.80
CAediting_345937ENST00000421397.4chr4_2007101_--225.60-219.10-223.80
CAediting_345938ENST00000421397.4chr4_2007150_--218.70-219.10-223.80
CAediting_345939ENST00000421397.4chr4_2007185_--220.20-219.10-223.80
CAediting_345936ENST00000443203.4chr4_2007023_--228.50-229.20-229.50
CAediting_345937ENST00000443203.4chr4_2007101_--230.60-229.20-229.50
CAediting_345938ENST00000443203.4chr4_2007150_--228.80-229.20-229.50
CAediting_345939ENST00000443203.4chr4_2007185_--230.30-229.20-229.50
CAediting_345894ENST00000458616.1chr4_2003890_--308.50-307.30-331.40
CAediting_345895ENST00000458616.1chr4_2003894_--309.40-307.30-331.40
CAediting_345896ENST00000458616.1chr4_2003896_--309.00-307.30-331.40
CAediting_345897ENST00000458616.1chr4_2003908_--312.40-307.30-331.40
CAediting_345898ENST00000458616.1chr4_2003909_--310.00-307.30-331.40
CAediting_345899ENST00000458616.1chr4_2003927_--306.90-307.30-331.40
CAediting_345900ENST00000458616.1chr4_2003939_--311.20-307.30-331.40
CAediting_345901ENST00000458616.1chr4_2003959_--310.70-307.30-331.40
CAediting_345902ENST00000458616.1chr4_2003994_--308.30-307.30-331.40
CAediting_345903ENST00000458616.1chr4_2004037_--308.20-307.30-331.40
CAediting_345904ENST00000458616.1chr4_2004047_--309.30-307.30-331.40
CAediting_345905ENST00000458616.1chr4_2004059_--307.70-307.30-331.40
CAediting_345906ENST00000458616.1chr4_2004076_--307.80-307.30-331.40
CAediting_345907ENST00000458616.1chr4_2004077_--308.20-307.30-331.40
CAediting_345908ENST00000458616.1chr4_2004102_--306.60-307.30-331.40
CAediting_345909ENST00000458616.1chr4_2004133_--307.30-307.30-331.40
CAediting_345936ENST00000458616.1chr4_2007023_--306.60-307.30-331.40
CAediting_345937ENST00000458616.1chr4_2007101_--310.50-307.30-331.40
CAediting_345938ENST00000458616.1chr4_2007150_--306.90-307.30-331.40
CAediting_345939ENST00000458616.1chr4_2007185_--306.60-307.30-331.40

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Relation with ADAR for NELFA

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LGGCAediting_345954chr4_2011305_-..6.83325210705354e-060.4289996001311877.78738892218328e-050.381024885620121

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Relation with cancer stages for NELFA

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for NELFA

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for NELFA

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for NELFA

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource