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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: UBA1 (CAeditome ID:7317)

Gene summary for UBA1

check button Gene summary
Gene informationGene symbol

UBA1

Gene ID

7317

Gene nameubiquitin like modifier activating enzyme 1
SynonymsA1S9|A1S9T|A1ST|AMCX1|CFAP124|GXP1|POC20|SMAX2|UBA1A|UBE1|UBE1X|VEXAS
Cytomap

Xp11.3

Type of geneprotein-coding
Descriptionubiquitin-like modifier-activating enzyme 1A1S9T and BN75 temperature sensitivity complementingPOC20 centriolar protein homologUBA1, ubiquitin-activating enzyme E1 homolog Atesticular secretory protein Li 63
Modification date20210518
UniProtAcc

P22314

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
UBA1

GO:0000792

Ubiquitin-like modifier-activating enzyme 1

1376922

UBA1

GO:0005765

Ubiquitin-like modifier-activating enzyme 1

1376922

UBA1

GO:0010008

Ubiquitin-like modifier-activating enzyme 1

1376922

UBA1

GO:0030057

Ubiquitin-like modifier-activating enzyme 1

1376922

UBA1

GO:0030867

Ubiquitin-like modifier-activating enzyme 1

1376922

UBA1

GO:0004839

Ubiquitin-like modifier-activating enzyme 1

12629039

UBA1

GO:0004839

Ubiquitin-like modifier-activating enzyme 1

21685362

UBA1

GO:0006974

Ubiquitin-like modifier-activating enzyme 1

22456334

UBA1

GO:0005634

Ubiquitin-like modifier-activating enzyme 1

1376922

UBA1

GO:0005634

Ubiquitin-like modifier-activating enzyme 1

22456334

UBA1

GO:0005654

Ubiquitin-like modifier-activating enzyme 1

0000052

UBA1

GO:0005737

Ubiquitin-like modifier-activating enzyme 1

1376922

UBA1

GO:0005739

Ubiquitin-like modifier-activating enzyme 1

1376922


Top

RNA A-to-I events for UBA1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000130985.15
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1505970(47195293, +), CAediting_1505971(47195376, +), CAediting_1505972(47195379, +), CAediting_1505973(47195395, +), CAediting_1505974(47195405, +), CAediting_1505975(47198443, +), CAediting_1505976(47198627, +), CAediting_1505977(47203798, +), CAediting_1505978(47203826, +), CAediting_1505979(47203829, +), CAediting_1505980(47203848, +), CAediting_1505981(47203849, +), CAediting_1505982(47203878, +), CAediting_1505983(47203890, +), CAediting_1505984(47203922, +), CAediting_1505985(47203927, +), CAediting_1505986(47203937, +), CAediting_1505987(47204000, +), CAediting_1505988(47204009, +), CAediting_1505989(47204010, +), CAediting_1505990(47204022, +), CAediting_1505991(47205378, +), CAediting_1505992(47205585, +), CAediting_1505993(47205599, +), CAediting_1505994(47205607, +), CAediting_1505995(47205608, +), CAediting_1505996(47205613, +), CAediting_1505997(47205639, +), CAediting_1505998(47205644, +), CAediting_1505999(47205652, +), CAediting_1506000(47205667, +), CAediting_1506001(47205676, +), CAediting_1506002(47205694, +), CAediting_1506003(47205695, +), CAediting_1506004(47205698, +), CAediting_1506005(47205701, +), CAediting_1506006(47205702, +), CAediting_1506007(47205703, +), CAediting_1506008(47205704, +), CAediting_1506009(47205711, +), CAediting_1506010(47205723, +), CAediting_1506011(47205727, +), CAediting_1506012(47205739, +), CAediting_1506013(47205743, +), CAediting_1506014(47205763, +), CAediting_1506015(47205774, +), CAediting_1506016(47205783, +), CAediting_1506017(47205788, +), CAediting_1506018(47205795, +), CAediting_1506019(47205799, +), CAediting_1506020(47205809, +), CAediting_1506021(47205834, +), CAediting_1506022(47205865, +), CAediting_1506023(47207724, +), CAediting_1506024(47208085, +), CAediting_1506025(47208171, +), CAediting_1506026(47208176, +), CAediting_1506027(47208184, +), CAediting_1506028(47208188, +), CAediting_1506029(47208195, +), CAediting_1506030(47208214, +), CAediting_1506031(47208228, +), CAediting_1506032(47208231, +), CAediting_1506033(47208307, +), CAediting_1506034(47208373, +), CAediting_1506035(47208384, +), CAediting_1506036(47208385, +), CAediting_1506037(47208399, +), CAediting_1506038(47208403, +), CAediting_1506039(47208416, +), CAediting_1506040(47208424, +), CAediting_1506041(47208426, +), CAediting_1506042(47208438, +), CAediting_1506043(47208446, +), CAediting_1506044(47208447, +), CAediting_1506045(47208665, +), CAediting_1506046(47208677, +), CAediting_1506047(47208685, +), CAediting_1506048(47208701, +), CAediting_1506049(47208715, +), CAediting_1506050(47208722, +), CAediting_1506051(47208747, +), CAediting_1506052(47208748, +), CAediting_1506053(47208749, +), CAediting_1506054(47208763, +), CAediting_1506055(47208817, +), CAediting_1506056(47208827, +), CAediting_1506057(47208829, +), CAediting_1506058(47208833, +), CAediting_1506059(47208835, +), CAediting_1506060(47208836, +), CAediting_1506061(47208841, +), CAediting_1506062(47208844, +), CAediting_1506063(47208848, +), CAediting_1506064(47208856, +), CAediting_1506065(47208857, +), CAediting_1506066(47208864, +), CAediting_1506067(47208875, +), CAediting_1506068(47208880, +), CAediting_1506069(47208883, +), CAediting_1506070(47208888, +), CAediting_1506071(47208889, +), CAediting_1506072(47208894, +), CAediting_1506073(47208899, +), CAediting_1506074(47208904, +), CAediting_1506075(47208906, +), CAediting_1506076(47208908, +), CAediting_1506077(47208911, +), CAediting_1506078(47208912, +), CAediting_1506079(47208925, +), CAediting_1506080(47208927, +), CAediting_1506081(47208930, +), CAediting_1506082(47208931, +), CAediting_1506083(47208938, +), CAediting_1506084(47208939, +), CAediting_1506085(47208940, +), CAediting_1506086(47208941, +), CAediting_1506087(47208944, +), CAediting_1506088(47208960, +), CAediting_1506089(47208976, +), CAediting_1506090(47208980, +), CAediting_1506091(47208987, +), CAediting_1506092(47208993, +), CAediting_1506093(47209011, +), CAediting_1506094(47209012, +), CAediting_1506095(47209019, +), CAediting_1506096(47209024, +), CAediting_1506097(47209025, +), CAediting_1506098(47209036, +), CAediting_1506099(47209073, +), CAediting_1506100(47209095, +), CAediting_1506101(47209105, +), CAediting_1506102(47209176, +), CAediting_1506103(47209178, +), CAediting_1506104(47209180, +), CAediting_1506105(47209194, +), CAediting_1506106(47209198, +), CAediting_1506107(47209219, +), CAediting_1506108(47209229, +), CAediting_1506109(47209235, +), CAediting_1506110(47209255, +), CAediting_1506111(47209257, +), CAediting_1506112(47209271, +), CAediting_1506113(47209283, +), CAediting_1506114(47209290, +), CAediting_1506115(47209293, +), CAediting_1506116(47209295, +), CAediting_1506117(47209299, +), CAediting_1506118(47209337, +), CAediting_1506119(47209351, +), CAediting_1506120(47209354, +), CAediting_1506121(47209363, +), CAediting_1506122(47209388, +), CAediting_1506123(47209406, +), CAediting_1506124(47209428, +), CAediting_1506125(47209430, +), CAediting_1506126(47209441, +),

Top

RNA editing positional annotations for UBA1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_1506119chrX_47209351_+nonsynonymous SNVENST00000377269.3c.A11Gp.H4RDBN
CAediting_1506120chrX_47209354_+nonsynonymous SNVENST00000377269.3c.A14Gp.H5RDBN
CAediting_1506121chrX_47209363_+nonsynonymous SNVENST00000377269.3c.A23Gp.Q8RDBN
CAediting_1506126chrX_47209441_+nonsynonymous SNVENST00000377269.3c.A101Gp.Y34CDBN

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1505970chrX_47195293_+intronic
CAediting_1505971chrX_47195376_+intronic
CAediting_1505972chrX_47195379_+intronic
CAediting_1505973chrX_47195395_+intronic
CAediting_1505974chrX_47195405_+intronic
CAediting_1505975chrX_47198443_+intronic
CAediting_1505976chrX_47198627_+intronic
CAediting_1505977chrX_47203798_+ncRNA_intronic
CAediting_1505978chrX_47203826_+ncRNA_intronic
CAediting_1505979chrX_47203829_+ncRNA_intronic
CAediting_1505980chrX_47203848_+ncRNA_intronic
CAediting_1505981chrX_47203849_+ncRNA_intronic
CAediting_1505982chrX_47203878_+ncRNA_intronic
CAediting_1505983chrX_47203890_+ncRNA_intronic
CAediting_1505984chrX_47203922_+ncRNA_intronic
CAediting_1505985chrX_47203927_+ncRNA_intronic
CAediting_1505986chrX_47203937_+ncRNA_intronic
CAediting_1505987chrX_47204000_+ncRNA_intronic
CAediting_1505988chrX_47204009_+ncRNA_intronic
CAediting_1505989chrX_47204010_+ncRNA_intronic
CAediting_1505990chrX_47204022_+ncRNA_intronic
CAediting_1505991chrX_47205378_+ncRNA_exonic
CAediting_1505992chrX_47205585_+ncRNA_exonic
CAediting_1505993chrX_47205599_+ncRNA_exonic
CAediting_1505994chrX_47205607_+ncRNA_exonic
CAediting_1505995chrX_47205608_+ncRNA_exonic
CAediting_1505996chrX_47205613_+ncRNA_exonic
CAediting_1505997chrX_47205639_+ncRNA_exonic
CAediting_1505998chrX_47205644_+ncRNA_exonic
CAediting_1505999chrX_47205652_+ncRNA_exonic
CAediting_1506000chrX_47205667_+ncRNA_exonic
CAediting_1506001chrX_47205676_+ncRNA_exonic
CAediting_1506002chrX_47205694_+ncRNA_exonic
CAediting_1506003chrX_47205695_+ncRNA_exonic
CAediting_1506004chrX_47205698_+ncRNA_exonic
CAediting_1506005chrX_47205701_+ncRNA_exonic
CAediting_1506006chrX_47205702_+ncRNA_exonic
CAediting_1506007chrX_47205703_+ncRNA_exonic
CAediting_1506008chrX_47205704_+ncRNA_exonic
CAediting_1506009chrX_47205711_+ncRNA_exonic
CAediting_1506010chrX_47205723_+ncRNA_exonic
CAediting_1506011chrX_47205727_+ncRNA_exonic
CAediting_1506012chrX_47205739_+ncRNA_exonic
CAediting_1506013chrX_47205743_+ncRNA_exonic
CAediting_1506014chrX_47205763_+ncRNA_exonic
CAediting_1506015chrX_47205774_+ncRNA_exonic
CAediting_1506016chrX_47205783_+ncRNA_exonic
CAediting_1506017chrX_47205788_+ncRNA_exonic
CAediting_1506018chrX_47205795_+ncRNA_exonic
CAediting_1506019chrX_47205799_+ncRNA_exonic
CAediting_1506020chrX_47205809_+ncRNA_exonic
CAediting_1506021chrX_47205834_+ncRNA_exonic
CAediting_1506022chrX_47205865_+ncRNA_exonic
CAediting_1506023chrX_47207724_+intronic
CAediting_1506024chrX_47208085_+intronic
CAediting_1506025chrX_47208171_+intronic
CAediting_1506026chrX_47208176_+intronic
CAediting_1506027chrX_47208184_+intronic
CAediting_1506028chrX_47208188_+intronic
CAediting_1506029chrX_47208195_+intronic
CAediting_1506030chrX_47208214_+intronic
CAediting_1506031chrX_47208228_+intronic
CAediting_1506032chrX_47208231_+intronic
CAediting_1506033chrX_47208307_+intronic
CAediting_1506034chrX_47208373_+intronic
CAediting_1506035chrX_47208384_+intronic
CAediting_1506036chrX_47208385_+intronic
CAediting_1506037chrX_47208399_+intronic
CAediting_1506038chrX_47208403_+intronic
CAediting_1506039chrX_47208416_+intronic
CAediting_1506040chrX_47208424_+intronic
CAediting_1506041chrX_47208426_+intronic
CAediting_1506042chrX_47208438_+intronic
CAediting_1506043chrX_47208446_+intronic
CAediting_1506044chrX_47208447_+intronic
CAediting_1506045chrX_47208665_+UTR5
CAediting_1506046chrX_47208677_+UTR5
CAediting_1506047chrX_47208685_+UTR5
CAediting_1506048chrX_47208701_+UTR5
CAediting_1506049chrX_47208715_+UTR5
CAediting_1506050chrX_47208722_+UTR5
CAediting_1506051chrX_47208747_+UTR5
CAediting_1506052chrX_47208748_+UTR5
CAediting_1506053chrX_47208749_+UTR5
CAediting_1506054chrX_47208763_+UTR5
CAediting_1506055chrX_47208817_+UTR5
CAediting_1506056chrX_47208827_+UTR5
CAediting_1506057chrX_47208829_+UTR5
CAediting_1506058chrX_47208833_+UTR5
CAediting_1506059chrX_47208835_+UTR5
CAediting_1506060chrX_47208836_+UTR5
CAediting_1506061chrX_47208841_+UTR5
CAediting_1506062chrX_47208844_+UTR5
CAediting_1506063chrX_47208848_+UTR5
CAediting_1506064chrX_47208856_+UTR5
CAediting_1506065chrX_47208857_+UTR5
CAediting_1506066chrX_47208864_+UTR5
CAediting_1506067chrX_47208875_+UTR5
CAediting_1506068chrX_47208880_+UTR5
CAediting_1506069chrX_47208883_+UTR5
CAediting_1506070chrX_47208888_+UTR5
CAediting_1506071chrX_47208889_+UTR5
CAediting_1506072chrX_47208894_+UTR5
CAediting_1506073chrX_47208899_+UTR5
CAediting_1506074chrX_47208904_+UTR5
CAediting_1506075chrX_47208906_+UTR5
CAediting_1506076chrX_47208908_+UTR5
CAediting_1506077chrX_47208911_+UTR5
CAediting_1506078chrX_47208912_+UTR5
CAediting_1506079chrX_47208925_+UTR5
CAediting_1506080chrX_47208927_+UTR5
CAediting_1506081chrX_47208930_+UTR5
CAediting_1506082chrX_47208931_+UTR5
CAediting_1506083chrX_47208938_+UTR5
CAediting_1506084chrX_47208939_+UTR5
CAediting_1506085chrX_47208940_+UTR5
CAediting_1506086chrX_47208941_+UTR5
CAediting_1506087chrX_47208944_+UTR5
CAediting_1506088chrX_47208960_+UTR5
CAediting_1506089chrX_47208976_+UTR5
CAediting_1506090chrX_47208980_+UTR5
CAediting_1506091chrX_47208987_+UTR5
CAediting_1506092chrX_47208993_+UTR5
CAediting_1506093chrX_47209011_+UTR5
CAediting_1506094chrX_47209012_+UTR5
CAediting_1506095chrX_47209019_+UTR5
CAediting_1506096chrX_47209024_+UTR5
CAediting_1506097chrX_47209025_+UTR5
CAediting_1506098chrX_47209036_+UTR5
CAediting_1506099chrX_47209073_+UTR5
CAediting_1506100chrX_47209095_+UTR5
CAediting_1506101chrX_47209105_+UTR5
CAediting_1506102chrX_47209176_+UTR5
CAediting_1506103chrX_47209178_+UTR5
CAediting_1506104chrX_47209180_+UTR5
CAediting_1506105chrX_47209194_+UTR5
CAediting_1506106chrX_47209198_+UTR5
CAediting_1506107chrX_47209219_+UTR5
CAediting_1506108chrX_47209229_+UTR5
CAediting_1506109chrX_47209235_+UTR5
CAediting_1506110chrX_47209255_+UTR5
CAediting_1506111chrX_47209257_+UTR5
CAediting_1506112chrX_47209271_+UTR5
CAediting_1506113chrX_47209283_+UTR5
CAediting_1506114chrX_47209290_+UTR5
CAediting_1506115chrX_47209293_+UTR5
CAediting_1506116chrX_47209295_+UTR5
CAediting_1506117chrX_47209299_+UTR5
CAediting_1506118chrX_47209337_+UTR5
CAediting_1506119chrX_47209351_+exonic
CAediting_1506120chrX_47209354_+exonic
CAediting_1506121chrX_47209363_+exonic
CAediting_1506122chrX_47209388_+exonic
CAediting_1506123chrX_47209406_+exonic
CAediting_1506124chrX_47209428_+exonic
CAediting_1506125chrX_47209430_+exonic
CAediting_1506126chrX_47209441_+exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1505970chrX_47195293_+SINEAluAluSx
CAediting_1505971chrX_47195376_+SINEAluAluSx
CAediting_1505972chrX_47195379_+SINEAluAluSx
CAediting_1505973chrX_47195395_+SINEAluAluSx
CAediting_1505974chrX_47195405_+SINEAluAluSx
CAediting_1505975chrX_47198443_+SINEMIRMIRc
CAediting_1505976chrX_47198627_+SINEMIRMIR
CAediting_1505977chrX_47203798_+SINEAluAluSp
CAediting_1505978chrX_47203826_+SINEAluAluSp
CAediting_1505979chrX_47203829_+SINEAluAluSp
CAediting_1505980chrX_47203848_+SINEAluAluSp
CAediting_1505981chrX_47203849_+SINEAluAluSp
CAediting_1505982chrX_47203878_+SINEAluAluSp
CAediting_1505983chrX_47203890_+SINEAluAluSp
CAediting_1505984chrX_47203922_+SINEAluAluSp
CAediting_1505985chrX_47203927_+SINEAluAluSp
CAediting_1505986chrX_47203937_+SINEAluAluSp
CAediting_1505987chrX_47204000_+SINEAluAluSp
CAediting_1505988chrX_47204009_+SINEAluAluSp
CAediting_1505989chrX_47204010_+SINEAluAluSp
CAediting_1505990chrX_47204022_+SINEAluAluSp
CAediting_1505992chrX_47205585_+SINEAluAluJb
CAediting_1505993chrX_47205599_+SINEAluAluJb
CAediting_1505994chrX_47205607_+SINEAluAluJb
CAediting_1505995chrX_47205608_+SINEAluAluJb
CAediting_1505996chrX_47205613_+SINEAluAluJb
CAediting_1505997chrX_47205639_+SINEAluAluJb
CAediting_1505998chrX_47205644_+SINEAluAluJb
CAediting_1505999chrX_47205652_+SINEAluAluJb
CAediting_1506000chrX_47205667_+SINEAluAluJb
CAediting_1506001chrX_47205676_+SINEAluAluJb
CAediting_1506002chrX_47205694_+SINEAluAluJb
CAediting_1506003chrX_47205695_+SINEAluAluJb
CAediting_1506004chrX_47205698_+SINEAluAluJb
CAediting_1506005chrX_47205701_+SINEAluAluJb
CAediting_1506006chrX_47205702_+SINEAluAluJb
CAediting_1506007chrX_47205703_+SINEAluAluJb
CAediting_1506008chrX_47205704_+SINEAluAluJb
CAediting_1506009chrX_47205711_+SINEAluAluJb
CAediting_1506010chrX_47205723_+SINEAluAluJb
CAediting_1506011chrX_47205727_+SINEAluAluJb
CAediting_1506012chrX_47205739_+SINEAluAluJb
CAediting_1506013chrX_47205743_+SINEAluAluJb
CAediting_1506014chrX_47205763_+SINEAluAluJb
CAediting_1506015chrX_47205774_+SINEAluAluJb
CAediting_1506016chrX_47205783_+SINEAluAluJb
CAediting_1506017chrX_47205788_+SINEAluAluJb
CAediting_1506018chrX_47205795_+SINEAluAluJb
CAediting_1506019chrX_47205799_+SINEAluAluJb
CAediting_1506020chrX_47205809_+SINEAluAluJb
CAediting_1506021chrX_47205834_+SINEAluAluJb
CAediting_1506022chrX_47205865_+SINEAluAluJb
CAediting_1506023chrX_47207724_+SINEMIRMIR
CAediting_1506024chrX_47208085_+SINEMIRMIR
CAediting_1506025chrX_47208171_+SINEAluAluJo
CAediting_1506026chrX_47208176_+SINEAluAluJo
CAediting_1506027chrX_47208184_+SINEAluAluJo
CAediting_1506028chrX_47208188_+SINEAluAluJo
CAediting_1506029chrX_47208195_+SINEAluAluJo
CAediting_1506030chrX_47208214_+SINEAluAluJo
CAediting_1506031chrX_47208228_+SINEAluAluJo
CAediting_1506032chrX_47208231_+SINEAluAluJo
CAediting_1506033chrX_47208307_+SINEAluAluJo
CAediting_1506034chrX_47208373_+SINEAluAluJo
CAediting_1506035chrX_47208384_+SINEAluAluJo
CAediting_1506036chrX_47208385_+SINEAluAluJo
CAediting_1506037chrX_47208399_+SINEAluAluJo
CAediting_1506038chrX_47208403_+SINEAluAluJo
CAediting_1506039chrX_47208416_+SINEAluAluJo
CAediting_1506040chrX_47208424_+SINEAluAluJo
CAediting_1506041chrX_47208426_+SINEAluAluJo
CAediting_1506042chrX_47208438_+SINEAluAluJo
CAediting_1506043chrX_47208446_+SINEAluAluJo
CAediting_1506044chrX_47208447_+SINEAluAluJo
CAediting_1506045chrX_47208665_+SINEAluAluSq
CAediting_1506046chrX_47208677_+SINEAluAluSq
CAediting_1506047chrX_47208685_+SINEAluAluSq
CAediting_1506048chrX_47208701_+SINEAluAluSq
CAediting_1506049chrX_47208715_+SINEAluAluSq
CAediting_1506050chrX_47208722_+SINEAluAluSq
CAediting_1506051chrX_47208747_+SINEAluAluSq
CAediting_1506052chrX_47208748_+SINEAluAluSq
CAediting_1506053chrX_47208749_+SINEAluAluSq
CAediting_1506054chrX_47208763_+SINEAluAluSq
CAediting_1506055chrX_47208817_+SINEAluAluJb
CAediting_1506056chrX_47208827_+SINEAluAluJb
CAediting_1506057chrX_47208829_+SINEAluAluJb
CAediting_1506058chrX_47208833_+SINEAluAluJb
CAediting_1506059chrX_47208835_+SINEAluAluJb
CAediting_1506060chrX_47208836_+SINEAluAluJb
CAediting_1506061chrX_47208841_+SINEAluAluJb
CAediting_1506062chrX_47208844_+SINEAluAluJb
CAediting_1506063chrX_47208848_+SINEAluAluJb
CAediting_1506064chrX_47208856_+SINEAluAluJb
CAediting_1506065chrX_47208857_+SINEAluAluJb
CAediting_1506066chrX_47208864_+SINEAluAluJb
CAediting_1506067chrX_47208875_+SINEAluAluJb
CAediting_1506068chrX_47208880_+SINEAluAluJb
CAediting_1506069chrX_47208883_+SINEAluAluJb
CAediting_1506070chrX_47208888_+SINEAluAluJb
CAediting_1506071chrX_47208889_+SINEAluAluJb
CAediting_1506072chrX_47208894_+SINEAluAluJb
CAediting_1506073chrX_47208899_+SINEAluAluJb
CAediting_1506074chrX_47208904_+SINEAluAluJb
CAediting_1506075chrX_47208906_+SINEAluAluJb
CAediting_1506076chrX_47208908_+SINEAluAluJb
CAediting_1506077chrX_47208911_+SINEAluAluJb
CAediting_1506078chrX_47208912_+SINEAluAluJb
CAediting_1506079chrX_47208925_+SINEAluAluJb
CAediting_1506080chrX_47208927_+SINEAluAluJb
CAediting_1506081chrX_47208930_+SINEAluAluJb
CAediting_1506082chrX_47208931_+SINEAluAluJb
CAediting_1506083chrX_47208938_+SINEAluAluJb
CAediting_1506084chrX_47208939_+SINEAluAluJb
CAediting_1506085chrX_47208940_+SINEAluAluJb
CAediting_1506086chrX_47208941_+SINEAluAluJb
CAediting_1506087chrX_47208944_+SINEAluAluJb
CAediting_1506088chrX_47208960_+SINEAluAluJb
CAediting_1506089chrX_47208976_+SINEAluAluJb
CAediting_1506090chrX_47208980_+SINEAluAluJb
CAediting_1506091chrX_47208987_+SINEAluAluJb
CAediting_1506092chrX_47208993_+SINEAluAluJb
CAediting_1506093chrX_47209011_+SINEAluAluJb
CAediting_1506094chrX_47209012_+SINEAluAluJb
CAediting_1506095chrX_47209019_+SINEAluAluJb
CAediting_1506096chrX_47209024_+SINEAluAluJb
CAediting_1506097chrX_47209025_+SINEAluAluJb
CAediting_1506098chrX_47209036_+SINEAluAluJb
CAediting_1506099chrX_47209073_+SINEAluAluJb
CAediting_1506100chrX_47209095_+SINEAluAluJb
CAediting_1506101chrX_47209105_+SINEAluAluJb
CAediting_1506102chrX_47209176_+SINEAluAluSx1
CAediting_1506103chrX_47209178_+SINEAluAluSx1
CAediting_1506104chrX_47209180_+SINEAluAluSx1
CAediting_1506105chrX_47209194_+SINEAluAluSx1
CAediting_1506106chrX_47209198_+SINEAluAluSx1
CAediting_1506107chrX_47209219_+SINEAluAluSx1
CAediting_1506108chrX_47209229_+SINEAluAluSx1
CAediting_1506109chrX_47209235_+SINEAluAluSx1
CAediting_1506110chrX_47209255_+SINEAluAluSx1
CAediting_1506111chrX_47209257_+SINEAluAluSx1
CAediting_1506112chrX_47209271_+SINEAluAluSx1
CAediting_1506113chrX_47209283_+SINEAluAluSx1
CAediting_1506114chrX_47209290_+SINEAluAluSx1
CAediting_1506115chrX_47209293_+SINEAluAluSx1
CAediting_1506116chrX_47209295_+SINEAluAluSx1
CAediting_1506117chrX_47209299_+SINEAluAluSx1
CAediting_1506118chrX_47209337_+SINEAluAluSx1
CAediting_1506119chrX_47209351_+SINEAluAluSx1
CAediting_1506120chrX_47209354_+SINEAluAluSx1
CAediting_1506121chrX_47209363_+SINEAluAluSx1
CAediting_1506122chrX_47209388_+SINEAluAluSx1
CAediting_1506123chrX_47209406_+SINEAluAluSx1
CAediting_1506124chrX_47209428_+SINEAluAluSx1
CAediting_1506125chrX_47209430_+SINEAluAluSx1
CAediting_1506126chrX_47209441_+SINEAluAluSx1

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RNA A-to-I editing events in the alternative splicing sites for UBA1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_1505976chrX_47198627_+47198626:471986345SS2+0iTAGGTCTGA1.23TGGGTCTGA-2.19
IRCAediting_1505976chrX_47198627_+47198626:471986345SS2+0iTAGGTCTGA1.23TGGGTCTGA-2.19
MEX_2CAediting_1505976chrX_47198627_+47198626:471986345SS2+0iTAGGTCTGA1.23TGGGTCTGA-2.19

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000130985.15.UBA1.
boxplot

check button Correlation between RNA A-to-I editing and PSI for ENSG00000130985.15.UBA1.
boxplot

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for UBA1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for UBA1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for UBA1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_86358chr1_109598906_+ENSG00000130985.15ENST00000377351hsa-miR-197-5p47214959472149657mer-m84721494147214966155-28.59
CAediting_86358chr1_109598906_+ENSG00000130985.15ENST00000335972hsa-miR-197-5p47214959472149657mer-m84721494147214966155-28.59
CAediting_86358chr1_109598906_+ENSG00000130985.15ENST00000377269hsa-miR-197-5p47214959472149657mer-m84721494147214966155-28.59

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for UBA1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for UBA1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LGGCAediting_1506028chrX_47208188_+0.003413493443766480.228049790779458....
BRCACAediting_1506028chrX_47208188_+2.01649916488729e-070.256026655797346....
CESCCAediting_1506028chrX_47208188_+0.001129709378471890.416964481809878....
LUSCCAediting_1506028chrX_47208188_+0.003878291775155650.3137018957324840.03808288211872980.228095810311318..
GBMCAediting_1506028chrX_47208188_+0.02145368391009340.318331193783849....
PRADCAediting_1506028chrX_47208188_+0.01028312144718180.318641721614355....
THCACAediting_1506028chrX_47208188_+0.04184366819727320.179467386640865....
BRCACAediting_1506034chrX_47208373_+0.03096574171138310.187190090699097....
LGGCAediting_1506065chrX_47208857_+0.03857459800878280.285029924562603....
BRCACAediting_1506065chrX_47208857_+0.009724319416188260.221806355428653....
OVCAediting_1506073chrX_47208899_+0.03357337030007180.150358519722863....
BRCACAediting_1506089chrX_47208976_+..0.03334546330103980.219726185810656..
LGGCAediting_1506104chrX_47209180_+0.0001696933780661680.273043239929402....
BLCACAediting_1506115chrX_47209293_+0.04946715750466380.271236175181827....
STADCAediting_1506123chrX_47209406_+....0.01333481815975480.231175885705448

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Relation with cancer stages for UBA1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
BLCApathologic_stageCAediting_1506104chrX_47209180_+0.03613356265127690.210901298815657
BLCApathologic_stageCAediting_1506123chrX_47209406_+0.03873884098675920.223329503436805
BRCApathologic_stageCAediting_1506064chrX_47208856_+0.04460653023824810.160525253941703
BRCApathologic_stageCAediting_1506070chrX_47208888_+0.0311790161171030.280864419769111
BRCApathologic_stageCAediting_1506103chrX_47209178_+0.02202482495386090.163095369805185
ESCApathologic_stageCAediting_1506115chrX_47209293_+0.0006252418150043150.369908800197351
KIRCpathologic_stageCAediting_1506073chrX_47208899_+0.01777155441866540.242756099488889
KIRCpathologic_stageCAediting_1506076chrX_47208908_+0.0139878162856980.268844931592415
KIRCpathologic_stageCAediting_1506104chrX_47209180_+0.009111096393606870.242197830665599
LUSCpathologic_stageCAediting_1506123chrX_47209406_+0.007822550291324550.281777466251962
TGCTpathologic_stageCAediting_1506104chrX_47209180_+0.019261824073401-0.447481978755706
THCApathologic_stageCAediting_1506076chrX_47208908_+0.02887490418412740.247555843325262

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Relation with survival for UBA1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LGGCAediting_1506115chrX_47209293_+0.03409313782475880.011491931.7055
BRCACAediting_1505998chrX_47205644_+0.02502295971216030.023871419283.9
UCECCAediting_1506103chrX_47209178_+0.0465049948415670.03894141.50417e-05

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RelatedDrugs for UBA1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for UBA1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
UBA1C1844934Arthrogryposis multiplex congenita, distal, X-linked2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
UBA1C0007137Squamous cell carcinoma1CTD_human