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Editing gene: GTF2H2C (CAeditome ID:728340)

Gene summary for GTF2H2C

Gene summary

Gene information	Gene symbol	GTF2H2C
	Gene ID	728340
	Gene name	GTF2H2 family member C
	Synonyms	GTF2H2C_2
	Cytomap	5q13.2
	Type of gene	protein-coding
	Description	general transcription factor IIH subunit 2-like proteingeneral transcription factor IIH polypeptide 2-like proteingeneral transcription factor IIH, polypeptide 2C
	Modification date	20210518
	UniProtAcc	Q6P1K8
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
GTF2H2C	GO:0016607	General transcription factor IIH subunit 2-like protein	0000052

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RNA A-to-I events for GTF2H2C

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000183474.14

RNA A-to-I editing events in Cancer.

CAediting_413557(69562721, +), CAediting_413558(69562728, +), CAediting_413559(69562745, +), CAediting_413560(69575497, +), CAediting_413561(69575498, +), CAediting_413562(69575515, +), CAediting_413563(69575517, +), CAediting_413564(69580139, +), CAediting_413565(69584175, +), CAediting_413566(69592787, +), CAediting_413567(69592828, +), CAediting_413568(69592829, +), CAediting_413569(69592833, +), CAediting_413570(69592849, +), CAediting_413571(69592853, +), CAediting_413572(69592858, +), CAediting_413573(69592889, +), CAediting_413574(69593749, +), CAediting_413575(69593779, +), CAediting_413576(69593786, +), CAediting_413577(69593789, +), CAediting_413578(69593815, +), CAediting_413579(69593821, +), CAediting_413580(69593825, +), CAediting_413581(69593832, +), CAediting_413582(69593848, +), CAediting_413583(69593856, +), CAediting_413584(69593857, +), CAediting_413585(69593861, +), CAediting_413586(69593918, +), CAediting_413587(69593920, +), CAediting_413588(69594093, +), CAediting_413589(69594254, +), CAediting_413590(69594266, +), CAediting_413591(69594272, +), CAediting_413592(69594291, +), CAediting_413593(69594300, +),

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RNA editing positional annotations for GTF2H2C using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_413557	chr5_69562721_+	ncRNA_exonic
CAediting_413558	chr5_69562728_+	ncRNA_exonic
CAediting_413559	chr5_69562745_+	ncRNA_exonic
CAediting_413560	chr5_69575497_+	ncRNA_intronic
CAediting_413561	chr5_69575498_+	ncRNA_intronic
CAediting_413562	chr5_69575515_+	ncRNA_intronic
CAediting_413563	chr5_69575517_+	ncRNA_intronic
CAediting_413564	chr5_69580139_+	intronic
CAediting_413565	chr5_69584175_+	intronic
CAediting_413566	chr5_69592787_+	UTR3
CAediting_413567	chr5_69592828_+	UTR3
CAediting_413568	chr5_69592829_+	UTR3
CAediting_413569	chr5_69592833_+	UTR3
CAediting_413570	chr5_69592849_+	UTR3
CAediting_413571	chr5_69592853_+	UTR3
CAediting_413572	chr5_69592858_+	UTR3
CAediting_413573	chr5_69592889_+	UTR3
CAediting_413574	chr5_69593749_+	ncRNA_intronic
CAediting_413575	chr5_69593779_+	ncRNA_intronic
CAediting_413576	chr5_69593786_+	ncRNA_intronic
CAediting_413577	chr5_69593789_+	ncRNA_intronic
CAediting_413578	chr5_69593815_+	ncRNA_intronic
CAediting_413579	chr5_69593821_+	ncRNA_intronic
CAediting_413580	chr5_69593825_+	ncRNA_intronic
CAediting_413581	chr5_69593832_+	ncRNA_intronic
CAediting_413582	chr5_69593848_+	ncRNA_intronic
CAediting_413583	chr5_69593856_+	ncRNA_intronic
CAediting_413584	chr5_69593857_+	ncRNA_intronic
CAediting_413585	chr5_69593861_+	ncRNA_intronic
CAediting_413586	chr5_69593918_+	ncRNA_intronic
CAediting_413587	chr5_69593920_+	ncRNA_intronic
CAediting_413588	chr5_69594093_+	ncRNA_intronic
CAediting_413589	chr5_69594254_+	ncRNA_exonic
CAediting_413590	chr5_69594266_+	ncRNA_exonic
CAediting_413591	chr5_69594272_+	ncRNA_exonic
CAediting_413592	chr5_69594291_+	ncRNA_exonic
CAediting_413593	chr5_69594300_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_413557	chr5_69562721_+	SINE	Alu	AluSz
CAediting_413558	chr5_69562728_+	SINE	Alu	AluSz
CAediting_413559	chr5_69562745_+	SINE	Alu	AluSz
CAediting_413560	chr5_69575497_+	SINE	Alu	AluSx3
CAediting_413561	chr5_69575498_+	SINE	Alu	AluSx3
CAediting_413562	chr5_69575515_+	SINE	Alu	AluSx3
CAediting_413563	chr5_69575517_+	SINE	Alu	AluSx3
CAediting_413564	chr5_69580139_+	SINE	Alu	AluY
CAediting_413565	chr5_69584175_+	SINE	Alu	AluSz6
CAediting_413566	chr5_69592787_+	SINE	Alu	AluSz
CAediting_413567	chr5_69592828_+	SINE	Alu	AluSz
CAediting_413568	chr5_69592829_+	SINE	Alu	AluSz
CAediting_413569	chr5_69592833_+	SINE	Alu	AluSz
CAediting_413570	chr5_69592849_+	SINE	Alu	AluSz
CAediting_413571	chr5_69592853_+	SINE	Alu	AluSz
CAediting_413572	chr5_69592858_+	SINE	Alu	AluSz
CAediting_413573	chr5_69592889_+	SINE	Alu	AluSz
CAediting_413574	chr5_69593749_+	SINE	Alu	AluY
CAediting_413575	chr5_69593779_+	SINE	Alu	AluY
CAediting_413576	chr5_69593786_+	SINE	Alu	AluY
CAediting_413577	chr5_69593789_+	SINE	Alu	AluY
CAediting_413578	chr5_69593815_+	SINE	Alu	AluY
CAediting_413579	chr5_69593821_+	SINE	Alu	AluY
CAediting_413580	chr5_69593825_+	SINE	Alu	AluY
CAediting_413581	chr5_69593832_+	SINE	Alu	AluY
CAediting_413582	chr5_69593848_+	SINE	Alu	AluY
CAediting_413583	chr5_69593856_+	SINE	Alu	AluY
CAediting_413584	chr5_69593857_+	SINE	Alu	AluY
CAediting_413585	chr5_69593861_+	SINE	Alu	AluY
CAediting_413586	chr5_69593918_+	SINE	Alu	AluY
CAediting_413587	chr5_69593920_+	SINE	Alu	AluY
CAediting_413588	chr5_69594093_+	SINE	Alu	AluSx1
CAediting_413589	chr5_69594254_+	SINE	Alu	AluSx1
CAediting_413590	chr5_69594266_+	SINE	Alu	AluSx1
CAediting_413591	chr5_69594272_+	SINE	Alu	AluSx1
CAediting_413592	chr5_69594291_+	SINE	Alu	AluSx1
CAediting_413593	chr5_69594300_+	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for GTF2H2C

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000183474.14.GTF2H2C.

Correlation between RNA A-to-I editing and PSI for ENSG00000183474.14.GTF2H2C.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for GTF2H2C

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_413585.ENSG00000183474.GTF2H2C.png
Soverview

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Protein coding region RNA A-to-I editings for GTF2H2C

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for GTF2H2C

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000510979	hsa-miR-10400-3p	69592826	69592832	7mer-m8	69592814	69592833	141.00	-23.04
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000510979	hsa-miR-4437	69592825	69592832	8mer-1a	69592812	69592832	146.00	-19.59
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000510979	hsa-miR-4674	69592826	69592832	7mer-m8	69592814	69592833	148.00	-24.84
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000446221	hsa-miR-10400-3p	69592826	69592832	7mer-m8	69592814	69592833	141.00	-23.04
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000446221	hsa-miR-4437	69592825	69592832	8mer-1a	69592812	69592832	146.00	-19.59
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000446221	hsa-miR-4674	69592826	69592832	7mer-m8	69592814	69592833	148.00	-24.84
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6511b-3p	69592848	69592853	6mer	69592832	69592854	144.00	-28.15
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6511b-3p	69592848	69592853	6mer	69592832	69592854	144.00	-28.15
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6784-3p	69592848	69592853	6mer	69592832	69592854	147.00	-30.38
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6511a-3p	69592848	69592853	6mer	69592833	69592854	140.00	-25.44
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6511b-3p	69592848	69592853	6mer	69592832	69592854	144.00	-28.15
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6511b-3p	69592848	69592853	6mer	69592832	69592854	144.00	-28.15
CAediting_413570	chr5_69592849_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6784-3p	69592848	69592853	6mer	69592832	69592854	147.00	-30.38
CAediting_413571	chr5_69592853_+	ENSG00000183474.14	ENST00000510979	hsa-miR-324-3p	69592846	69592852	7mer-m8	69592831	69592853	145.00	-25.24
CAediting_413571	chr5_69592853_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6075	69592850	69592857	8mer-1a	69592836	69592857	150.00	-25.04
CAediting_413571	chr5_69592853_+	ENSG00000183474.14	ENST00000446221	hsa-miR-324-3p	69592846	69592852	7mer-m8	69592831	69592853	145.00	-25.24
CAediting_413571	chr5_69592853_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6075	69592850	69592857	8mer-1a	69592836	69592857	150.00	-25.04

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_413569	chr5_69592833_+	ENSG00000183474.14	ENST00000510979	hsa-miR-1343-3p	69592829	69592835	7mer-m8	69592813	69592836	150	-24.17
CAediting_413573	chr5_69592889_+	ENSG00000183474.14	ENST00000510979	hsa-miR-200c-5p	69592885	69592891	7mer-m8	69592871	69592892	149	-11.15
CAediting_413574	chr5_69593749_+	ENSG00000183474.14	ENST00000510979	hsa-miR-3152-3p	69593745	69593751	7mer-m8	69593732	69593752	145	-18.08
CAediting_413571	chr5_69592853_+	ENSG00000183474.14	ENST00000510979	hsa-miR-4284	69592849	69592855	7mer-m8	69592839	69592856	151	-17.62
CAediting_413572	chr5_69592858_+	ENSG00000183474.14	ENST00000510979	hsa-miR-4638-5p	69592852	69592859	8mer-1a	69592840	69592859	146	-20.28
CAediting_413567	chr5_69592828_+	ENSG00000183474.14	ENST00000510979	hsa-miR-498-5p	69592822	69592828	7mer-m8	69592807	69592829	142	-9.71
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000510979	hsa-miR-498-5p	69592822	69592828	7mer-m8	69592807	69592829	142	-9.71
CAediting_413566	chr5_69592787_+	ENSG00000183474.14	ENST00000510979	hsa-miR-508-5p	69592782	69592788	7mer-m8	69592770	69592789	153	-18.91
CAediting_413573	chr5_69592889_+	ENSG00000183474.14	ENST00000510979	hsa-miR-550a-3p	69592885	69592891	7mer-m8	69592871	69592892	150	-15.67
CAediting_413573	chr5_69592889_+	ENSG00000183474.14	ENST00000510979	hsa-miR-550a-3p	69592885	69592891	7mer-m8	69592871	69592892	150	-15.67
CAediting_413573	chr5_69592889_+	ENSG00000183474.14	ENST00000510979	hsa-miR-550a-3p	69592885	69592891	7mer-m8	69592871	69592892	150	-15.67
CAediting_413573	chr5_69592889_+	ENSG00000183474.14	ENST00000510979	hsa-miR-550b-3p	69592883	69592890	8mer-1a	69592871	69592890	140	-13.17
CAediting_413573	chr5_69592889_+	ENSG00000183474.14	ENST00000510979	hsa-miR-550b-3p	69592883	69592890	8mer-1a	69592871	69592890	140	-13.17
CAediting_413569	chr5_69592833_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6742-3p	69592828	69592835	8mer-1a	69592816	69592835	145	-14.93
CAediting_413569	chr5_69592833_+	ENSG00000183474.14	ENST00000510979	hsa-miR-6783-3p	69592829	69592835	7mer-m8	69592816	69592836	146	-17.13
CAediting_413573	chr5_69592889_+	ENSG00000183474.14	ENST00000510979	hsa-miR-924	69592887	69592893	7mer-m8	69592875	69592894	142	-11.78
CAediting_413569	chr5_69592833_+	ENSG00000183474.14	ENST00000446221	hsa-miR-1343-3p	69592829	69592835	7mer-m8	69592813	69592836	150	-24.17
CAediting_413571	chr5_69592853_+	ENSG00000183474.14	ENST00000446221	hsa-miR-4284	69592849	69592855	7mer-m8	69592839	69592856	151	-17.62
CAediting_413572	chr5_69592858_+	ENSG00000183474.14	ENST00000446221	hsa-miR-4638-5p	69592852	69592859	8mer-1a	69592840	69592859	146	-20.28
CAediting_413567	chr5_69592828_+	ENSG00000183474.14	ENST00000446221	hsa-miR-498-5p	69592822	69592828	7mer-m8	69592807	69592829	142	-9.71
CAediting_413568	chr5_69592829_+	ENSG00000183474.14	ENST00000446221	hsa-miR-498-5p	69592822	69592828	7mer-m8	69592807	69592829	142	-9.71
CAediting_413566	chr5_69592787_+	ENSG00000183474.14	ENST00000446221	hsa-miR-508-5p	69592782	69592788	7mer-m8	69592770	69592789	153	-18.91
CAediting_413569	chr5_69592833_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6742-3p	69592828	69592835	8mer-1a	69592816	69592835	145	-14.93
CAediting_413569	chr5_69592833_+	ENSG00000183474.14	ENST00000446221	hsa-miR-6783-3p	69592829	69592835	7mer-m8	69592816	69592836	146	-17.13

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_688081	chr9_63819627_+	ENSG00000183474.14	ENST00000514069	hsa-miR-4477b	69572521	69572527	7mer-m8	69572509	69572528	149	-11.98
CAediting_688081	chr9_63819627_+	ENSG00000183474.14	ENST00000506129	hsa-miR-4477b	69572521	69572527	7mer-m8	69572509	69572528	149	-11.98
CAediting_688081	chr9_63819627_+	ENSG00000183474.14	ENST00000446221	hsa-miR-4477b	69572521	69572527	7mer-m8	69572509	69572528	149	-11.98
CAediting_1229415	chr17_67471547_+	ENSG00000183474.14	ENST00000511629	hsa-miR-548aa	69569322	69569328	7mer-m8	69569302	69569329	153	-12.7
CAediting_1351755	chr19_40282625_-	ENSG00000183474.14	ENST00000511629	hsa-miR-641	69569371	69569377	7mer-m8	69569355	69569378	140	-14.53
CAediting_1399425	chr20_1392958_-	ENSG00000183474.14	ENST00000511629	hsa-miR-6869-5p	69569912	69569918	7mer-m8	69569897	69569919	145	-23.43
CAediting_580943	chr7_100356700_+	ENSG00000183474.14	ENST00000511629	hsa-miR-6840-3p	69569763	69569769	7mer-m8	69569754	69569770	141	-27.37
CAediting_1229415	chr17_67471547_+	ENSG00000183474.14	ENST00000510979	hsa-miR-548aa	69593647	69593652	6mer	69593630	69593653	145	-15.1
CAediting_86358	chr1_109598906_+	ENSG00000183474.14	ENST00000510979	hsa-miR-197-5p	69592874	69592880	7mer-m8	69592861	69592881	166	-31.05
CAediting_1368054	chr19_46709310_-	ENSG00000183474.14	ENST00000446221	hsa-miR-320e	69592177	69592183	7mer-m8	69592164	69592184	147	-16.14
CAediting_1524209	chrX_134546392_-	ENSG00000183474.14	ENST00000511629	hsa-miR-503-5p	69569822	69569829	8mer-1a	69569807	69569829	145	-23.4

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_86358	chr1_109598906_+	ENSG00000183474.14	ENST00000511629	hsa-miR-197-5p	69569911	69569918	8mer-1a	69569890	69569918	146	-24.6
CAediting_414656	chr5_72878640_+	ENSG00000183474.14	ENST00000511629	hsa-miR-4804-3p	69568872	69568879	8mer-1a	69568859	69568879	147	-9.79
CAediting_1229413	chr17_67471544_+	ENSG00000183474.14	ENST00000511629	hsa-miR-548aa	69569084	69569090	7mer-m8	69569067	69569091	154	-5.51
CAediting_1229415	chr17_67471547_+	ENSG00000183474.14	ENST00000511629	hsa-miR-548aa	69569084	69569090	7mer-m8	69569067	69569091	154	-5.51
CAediting_228905	chr2_188297554_+	ENSG00000183474.14	ENST00000510979	hsa-miR-561-3p	69592310	69592316	7mer-m8	69592296	69592317	140	-5.76
CAediting_1306324	chr19_13836464_-	ENSG00000183474.14	ENST00000446221	hsa-miR-27a-3p	69592118	69592124	7mer-m8	69592105	69592125	140	-12.02
CAediting_1306323	chr19_13836462_-	ENSG00000183474.14	ENST00000446221	hsa-miR-27a-3p	69592118	69592124	7mer-m8	69592105	69592125	140	-12.02

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for GTF2H2C

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000380729.6	protein_coding
ENST00000446221.5	nonsense_mediated_decay
ENST00000505737.2	processed_transcript
ENST00000508325.4	retained_intron
ENST00000510979.4	protein_coding
ENST00000514069.5	nonsense_mediated_decay
ENST00000513959.2	processed_transcript

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_413557	ENST00000380729.6	chr5_69562721_+	-461.50	-462.30	-466.80
CAediting_413558	ENST00000380729.6	chr5_69562728_+	-466.30	-462.30	-466.80
CAediting_413559	ENST00000380729.6	chr5_69562745_+	-465.80	-462.30	-466.80
CAediting_413566	ENST00000446221.5	chr5_69592787_+	-510.90	-508.10	-517.70
CAediting_413567	ENST00000446221.5	chr5_69592828_+	-508.90	-508.10	-517.70
CAediting_413568	ENST00000446221.5	chr5_69592829_+	-510.70	-508.10	-517.70
CAediting_413569	ENST00000446221.5	chr5_69592833_+	-510.10	-508.10	-517.70
CAediting_413570	ENST00000446221.5	chr5_69592849_+	-508.10	-508.10	-517.70
CAediting_413571	ENST00000446221.5	chr5_69592853_+	-508.10	-508.10	-517.70
CAediting_413572	ENST00000446221.5	chr5_69592858_+	-508.10	-508.10	-517.70
CAediting_413557	ENST00000505737.2	chr5_69562721_+	-168.90	-167.80	-173.70
CAediting_413558	ENST00000505737.2	chr5_69562728_+	-169.40	-167.80	-173.70
CAediting_413559	ENST00000505737.2	chr5_69562745_+	-169.10	-167.80	-173.70
CAediting_413557	ENST00000508325.4	chr5_69562721_+	-126.50	-127.20	-134.10
CAediting_413558	ENST00000508325.4	chr5_69562728_+	-133.60	-127.20	-134.10
CAediting_413559	ENST00000508325.4	chr5_69562745_+	-132.00	-127.20	-134.10
CAediting_413566	ENST00000510979.4	chr5_69592787_+	-788.00	-786.10	-795.90
CAediting_413567	ENST00000510979.4	chr5_69592828_+	-785.60	-786.10	-795.90
CAediting_413568	ENST00000510979.4	chr5_69592829_+	-787.50	-786.10	-795.90
CAediting_413569	ENST00000510979.4	chr5_69592833_+	-787.50	-786.10	-795.90
CAediting_413570	ENST00000510979.4	chr5_69592849_+	-785.40	-786.10	-795.90
CAediting_413571	ENST00000510979.4	chr5_69592853_+	-787.40	-786.10	-795.90
CAediting_413572	ENST00000510979.4	chr5_69592858_+	-786.10	-786.10	-795.90
CAediting_413573	ENST00000510979.4	chr5_69592889_+	-787.20	-786.10	-795.90
CAediting_413574	ENST00000510979.4	chr5_69593749_+	-786.10	-786.10	-795.90
CAediting_413557	ENST00000514069.5	chr5_69562721_+	-130.60	-131.30	-136.30
CAediting_413558	ENST00000514069.5	chr5_69562728_+	-135.80	-131.30	-136.30
CAediting_413559	ENST00000514069.5	chr5_69562745_+	-134.60	-131.30	-136.30
CAediting_413589	ENST00000513959.2	chr5_69594254_+	-209.60	-208.70	-213.30
CAediting_413590	ENST00000513959.2	chr5_69594266_+	-207.90	-208.70	-213.30
CAediting_413591	ENST00000513959.2	chr5_69594272_+	-209.00	-208.70	-213.30
CAediting_413592	ENST00000513959.2	chr5_69594291_+	-208.70	-208.70	-213.30
CAediting_413593	ENST00000513959.2	chr5_69594300_+	-208.70	-208.70	-213.30

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Relation with ADAR for GTF2H2C

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_413581	chr5_69593832_+	0.00134525349346208	0.363564046872106	.	.	.	.

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Relation with cancer stages for GTF2H2C

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for GTF2H2C

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for GTF2H2C

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for GTF2H2C

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene