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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ZEB1 (CAeditome ID:6935)

Gene summary for ZEB1

check button Gene summary
Gene informationGene symbol

ZEB1

Gene ID

6935

Gene namezinc finger E-box binding homeobox 1
SynonymsAREB6|BZP|DELTAEF1|FECD6|NIL2A|PPCD3|TCF8|ZFHEP|ZFHX1A
Cytomap

10p11.22

Type of geneprotein-coding
Descriptionzinc finger E-box-binding homeobox 1delta-crystallin enhancer binding factor 1negative regulator of IL2posterior polymorphous corneal dystrophy 3transcription factor 8 (represses interleukin 2 expression)zinc finger homeodomain enhancer-binding prote
Modification date20210531
UniProtAcc

P37275

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ZEB1

GO:0001227

Zinc finger E-box-binding homeobox 1

23765923

ZEB1

GO:0001227

Zinc finger E-box-binding homeobox 1

23814079

ZEB1

GO:0000122

Zinc finger E-box-binding homeobox 1

23765923

ZEB1

GO:0000122

Zinc finger E-box-binding homeobox 1

23814079

ZEB1

GO:0045892

Zinc finger E-box-binding homeobox 1

20418909

ZEB1

GO:0005634

Zinc finger E-box-binding homeobox 1

20418909

ZEB1

GO:0005634

Zinc finger E-box-binding homeobox 1

23814079

ZEB1

GO:0005634

Zinc finger E-box-binding homeobox 1

25190660

ZEB1

GO:0005654

Zinc finger E-box-binding homeobox 1

0000052

ZEB1

GO:0005829

Zinc finger E-box-binding homeobox 1

0000052


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RNA A-to-I events for ZEB1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000148516.20

check button RNA A-to-I editing events in Cancer.
CAediting_742334(31337784, +), CAediting_742335(31337814, +), CAediting_742336(31337824, +), CAediting_742337(31337864, +), CAediting_742338(31337881, +), CAediting_742339(31337893, +), CAediting_742340(31337957, +), CAediting_742341(31339492, +), CAediting_742342(31339514, +), CAediting_742343(31339582, +), CAediting_742344(31339592, +), CAediting_742345(31339612, +), CAediting_742346(31339623, +), CAediting_742347(31339663, +), CAediting_742348(31339676, +), CAediting_742349(31339702, +), CAediting_742350(31339711, +), CAediting_742351(31339715, +), CAediting_742352(31339716, +), CAediting_742353(31347401, +), CAediting_742354(31347420, +), CAediting_742355(31347470, +), CAediting_742356(31347490, +), CAediting_742357(31348302, +), CAediting_742358(31348309, +), CAediting_742359(31348443, +), CAediting_742360(31348444, +), CAediting_742361(31381747, +), CAediting_742362(31381755, +), CAediting_742363(31381756, +), CAediting_742364(31381761, +), CAediting_742365(31381778, +), CAediting_742366(31381791, +), CAediting_742367(31381796, +), CAediting_742368(31381801, +), CAediting_742369(31381809, +), CAediting_742370(31381810, +), CAediting_742371(31381815, +), CAediting_742372(31381833, +), CAediting_742373(31381835, +), CAediting_742374(31381846, +), CAediting_742375(31381849, +), CAediting_742376(31381850, +), CAediting_742377(31381851, +), CAediting_742378(31381852, +), CAediting_742379(31381853, +), CAediting_742380(31381855, +), CAediting_742381(31381861, +), CAediting_742382(31381864, +), CAediting_742383(31381890, +), CAediting_742384(31381896, +), CAediting_742385(31381900, +), CAediting_742386(31381907, +), CAediting_742387(31381912, +), CAediting_742388(31381913, +), CAediting_742389(31381920, +), CAediting_742390(31381936, +), CAediting_742391(31381943, +), CAediting_742392(31381952, +), CAediting_742393(31381956, +), CAediting_742394(31381961, +), CAediting_742395(31381963, +), CAediting_742396(31381971, +), CAediting_742397(31381976, +), CAediting_742398(31381981, +), CAediting_742399(31383282, +), CAediting_742400(31384032, +), CAediting_742401(31384043, +), CAediting_742402(31384076, +), CAediting_742403(31384101, +), CAediting_742404(31384102, +), CAediting_742405(31384105, +), CAediting_742406(31384115, +), CAediting_742407(31384121, +), CAediting_742408(31384156, +), CAediting_742409(31384212, +), CAediting_742410(31384214, +), CAediting_742411(31384244, +), CAediting_742412(31384250, +), CAediting_742413(31384252, +), CAediting_742414(31387263, +), CAediting_742415(31391155, +), CAediting_742416(31410153, +), CAediting_742417(31429467, +), CAediting_742418(31429470, +), CAediting_742419(31429474, +), CAediting_742420(31429477, +), CAediting_742421(31429478, +), CAediting_742422(31432410, +), CAediting_742423(31432424, +), CAediting_742424(31432495, +), CAediting_742425(31442469, +), CAediting_742426(31464273, +), CAediting_742427(31464274, +), CAediting_742428(31464323, +), CAediting_742429(31464341, +), CAediting_742430(31465638, +), CAediting_742431(31465662, +), CAediting_742432(31465683, +), CAediting_742433(31465714, +), CAediting_742434(31465747, +),

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RNA editing positional annotations for ZEB1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_742334chr10_31337784_+ncRNA_intronic
CAediting_742335chr10_31337814_+ncRNA_intronic
CAediting_742336chr10_31337824_+ncRNA_intronic
CAediting_742337chr10_31337864_+ncRNA_intronic
CAediting_742338chr10_31337881_+ncRNA_intronic
CAediting_742339chr10_31337893_+ncRNA_intronic
CAediting_742340chr10_31337957_+ncRNA_intronic
CAediting_742341chr10_31339492_+ncRNA_intronic
CAediting_742342chr10_31339514_+ncRNA_intronic
CAediting_742343chr10_31339582_+ncRNA_intronic
CAediting_742344chr10_31339592_+ncRNA_intronic
CAediting_742345chr10_31339612_+ncRNA_intronic
CAediting_742346chr10_31339623_+ncRNA_intronic
CAediting_742347chr10_31339663_+ncRNA_intronic
CAediting_742348chr10_31339676_+ncRNA_intronic
CAediting_742349chr10_31339702_+ncRNA_intronic
CAediting_742350chr10_31339711_+ncRNA_intronic
CAediting_742351chr10_31339715_+ncRNA_intronic
CAediting_742352chr10_31339716_+ncRNA_intronic
CAediting_742353chr10_31347401_+ncRNA_intronic
CAediting_742354chr10_31347420_+ncRNA_intronic
CAediting_742355chr10_31347470_+ncRNA_intronic
CAediting_742356chr10_31347490_+ncRNA_intronic
CAediting_742357chr10_31348302_+ncRNA_intronic
CAediting_742358chr10_31348309_+ncRNA_intronic
CAediting_742359chr10_31348443_+ncRNA_intronic
CAediting_742360chr10_31348444_+ncRNA_intronic
CAediting_742361chr10_31381747_+ncRNA_exonic
CAediting_742362chr10_31381755_+ncRNA_exonic
CAediting_742363chr10_31381756_+ncRNA_exonic
CAediting_742364chr10_31381761_+ncRNA_exonic
CAediting_742365chr10_31381778_+ncRNA_exonic
CAediting_742366chr10_31381791_+ncRNA_exonic
CAediting_742367chr10_31381796_+ncRNA_exonic
CAediting_742368chr10_31381801_+ncRNA_exonic
CAediting_742369chr10_31381809_+ncRNA_exonic
CAediting_742370chr10_31381810_+ncRNA_exonic
CAediting_742371chr10_31381815_+ncRNA_exonic
CAediting_742372chr10_31381833_+ncRNA_intronic
CAediting_742373chr10_31381835_+ncRNA_intronic
CAediting_742374chr10_31381846_+ncRNA_intronic
CAediting_742375chr10_31381849_+ncRNA_intronic
CAediting_742376chr10_31381850_+ncRNA_intronic
CAediting_742377chr10_31381851_+ncRNA_intronic
CAediting_742378chr10_31381852_+ncRNA_intronic
CAediting_742379chr10_31381853_+ncRNA_intronic
CAediting_742380chr10_31381855_+ncRNA_intronic
CAediting_742381chr10_31381861_+ncRNA_intronic
CAediting_742382chr10_31381864_+ncRNA_intronic
CAediting_742383chr10_31381890_+ncRNA_intronic
CAediting_742384chr10_31381896_+ncRNA_intronic
CAediting_742385chr10_31381900_+ncRNA_intronic
CAediting_742386chr10_31381907_+ncRNA_intronic
CAediting_742387chr10_31381912_+ncRNA_intronic
CAediting_742388chr10_31381913_+ncRNA_intronic
CAediting_742389chr10_31381920_+ncRNA_intronic
CAediting_742390chr10_31381936_+ncRNA_intronic
CAediting_742391chr10_31381943_+ncRNA_intronic
CAediting_742392chr10_31381952_+ncRNA_intronic
CAediting_742393chr10_31381956_+ncRNA_intronic
CAediting_742394chr10_31381961_+ncRNA_intronic
CAediting_742395chr10_31381963_+ncRNA_intronic
CAediting_742396chr10_31381971_+ncRNA_intronic
CAediting_742397chr10_31381976_+ncRNA_intronic
CAediting_742398chr10_31381981_+ncRNA_intronic
CAediting_742399chr10_31383282_+ncRNA_intronic
CAediting_742400chr10_31384032_+ncRNA_intronic
CAediting_742401chr10_31384043_+ncRNA_intronic
CAediting_742402chr10_31384076_+ncRNA_intronic
CAediting_742403chr10_31384101_+ncRNA_intronic
CAediting_742404chr10_31384102_+ncRNA_intronic
CAediting_742405chr10_31384105_+ncRNA_intronic
CAediting_742406chr10_31384115_+ncRNA_intronic
CAediting_742407chr10_31384121_+ncRNA_intronic
CAediting_742408chr10_31384156_+ncRNA_intronic
CAediting_742409chr10_31384212_+ncRNA_intronic
CAediting_742410chr10_31384214_+ncRNA_intronic
CAediting_742411chr10_31384244_+ncRNA_intronic
CAediting_742412chr10_31384250_+ncRNA_intronic
CAediting_742413chr10_31384252_+ncRNA_intronic
CAediting_742414chr10_31387263_+ncRNA_exonic
CAediting_742415chr10_31391155_+ncRNA_intronic
CAediting_742416chr10_31410153_+ncRNA_intronic
CAediting_742417chr10_31429467_+ncRNA_intronic
CAediting_742418chr10_31429470_+ncRNA_intronic
CAediting_742419chr10_31429474_+ncRNA_intronic
CAediting_742420chr10_31429477_+ncRNA_intronic
CAediting_742421chr10_31429478_+ncRNA_intronic
CAediting_742422chr10_31432410_+ncRNA_intronic
CAediting_742423chr10_31432424_+ncRNA_intronic
CAediting_742424chr10_31432495_+ncRNA_intronic
CAediting_742425chr10_31442469_+ncRNA_intronic
CAediting_742426chr10_31464273_+ncRNA_intronic
CAediting_742427chr10_31464274_+ncRNA_intronic
CAediting_742428chr10_31464323_+ncRNA_intronic
CAediting_742429chr10_31464341_+ncRNA_intronic
CAediting_742430chr10_31465638_+ncRNA_intronic
CAediting_742431chr10_31465662_+ncRNA_intronic
CAediting_742432chr10_31465683_+ncRNA_intronic
CAediting_742433chr10_31465714_+ncRNA_intronic
CAediting_742434chr10_31465747_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_742334chr10_31337784_+SINEAluAluSg4
CAediting_742335chr10_31337814_+SINEAluAluSg4
CAediting_742336chr10_31337824_+SINEAluAluSg4
CAediting_742337chr10_31337864_+SINEAluAluSg4
CAediting_742338chr10_31337881_+SINEAluAluSg4
CAediting_742339chr10_31337893_+SINEAluAluSg4
CAediting_742340chr10_31337957_+SINEAluAluSg4
CAediting_742341chr10_31339492_+SINEAluAluSx3
CAediting_742342chr10_31339514_+SINEAluAluSx3
CAediting_742343chr10_31339582_+SINEAluAluSx3
CAediting_742344chr10_31339592_+SINEAluAluSx3
CAediting_742345chr10_31339612_+SINEAluAluSx3
CAediting_742346chr10_31339623_+SINEAluAluSx3
CAediting_742347chr10_31339663_+SINEAluAluSx3
CAediting_742348chr10_31339676_+SINEAluAluSx3
CAediting_742349chr10_31339702_+SINEAluAluSx3
CAediting_742350chr10_31339711_+SINEAluAluSx3
CAediting_742351chr10_31339715_+SINEAluAluSx3
CAediting_742352chr10_31339716_+SINEAluAluSx3
CAediting_742353chr10_31347401_+SINEAluFLAM_A
CAediting_742354chr10_31347420_+SINEAluFLAM_A
CAediting_742355chr10_31347470_+SINEAluFLAM_A
CAediting_742356chr10_31347490_+SINEAluFLAM_A
CAediting_742357chr10_31348302_+SINEAluAluSx1
CAediting_742358chr10_31348309_+SINEAluAluSx1
CAediting_742359chr10_31348443_+SINEAluAluSx1
CAediting_742360chr10_31348444_+SINEAluAluSx1
CAediting_742361chr10_31381747_+SINEAluAluSz
CAediting_742362chr10_31381755_+SINEAluAluSz
CAediting_742363chr10_31381756_+SINEAluAluSz
CAediting_742364chr10_31381761_+SINEAluAluSz
CAediting_742365chr10_31381778_+SINEAluAluSz
CAediting_742366chr10_31381791_+SINEAluAluSz
CAediting_742367chr10_31381796_+SINEAluAluSz
CAediting_742368chr10_31381801_+SINEAluAluSz
CAediting_742369chr10_31381809_+SINEAluAluSz
CAediting_742370chr10_31381810_+SINEAluAluSz
CAediting_742371chr10_31381815_+SINEAluAluSz
CAediting_742372chr10_31381833_+SINEAluAluSz
CAediting_742373chr10_31381835_+SINEAluAluSz
CAediting_742374chr10_31381846_+SINEAluAluSz
CAediting_742375chr10_31381849_+SINEAluAluSz
CAediting_742376chr10_31381850_+SINEAluAluSz
CAediting_742377chr10_31381851_+SINEAluAluSz
CAediting_742378chr10_31381852_+SINEAluAluSz
CAediting_742379chr10_31381853_+SINEAluAluSz
CAediting_742380chr10_31381855_+SINEAluAluSz
CAediting_742381chr10_31381861_+SINEAluAluSz
CAediting_742382chr10_31381864_+SINEAluAluSz
CAediting_742383chr10_31381890_+SINEAluAluSz
CAediting_742384chr10_31381896_+SINEAluAluSz
CAediting_742385chr10_31381900_+SINEAluAluSz
CAediting_742386chr10_31381907_+SINEAluAluSz
CAediting_742387chr10_31381912_+SINEAluAluSz
CAediting_742388chr10_31381913_+SINEAluAluSz
CAediting_742389chr10_31381920_+SINEAluAluSz
CAediting_742390chr10_31381936_+SINEAluAluSz
CAediting_742391chr10_31381943_+SINEAluAluSz
CAediting_742392chr10_31381952_+SINEAluAluSz
CAediting_742393chr10_31381956_+SINEAluAluSz
CAediting_742394chr10_31381961_+SINEAluAluSz
CAediting_742395chr10_31381963_+SINEAluAluSz
CAediting_742396chr10_31381971_+SINEAluAluSz
CAediting_742397chr10_31381976_+SINEAluAluSz
CAediting_742398chr10_31381981_+SINEAluAluSz
CAediting_742399chr10_31383282_+DNAhAT-CharlieMER3
CAediting_742400chr10_31384032_+SINEAluAluSz
CAediting_742401chr10_31384043_+SINEAluAluSz
CAediting_742402chr10_31384076_+SINEAluAluSz
CAediting_742403chr10_31384101_+SINEAluAluSz
CAediting_742404chr10_31384102_+SINEAluAluSz
CAediting_742405chr10_31384105_+SINEAluAluSz
CAediting_742406chr10_31384115_+SINEAluAluSz
CAediting_742407chr10_31384121_+SINEAluAluSz
CAediting_742408chr10_31384156_+SINEAluAluSz
CAediting_742409chr10_31384212_+SINEAluAluSz
CAediting_742410chr10_31384214_+SINEAluAluSz
CAediting_742411chr10_31384244_+SINEAluAluSz
CAediting_742412chr10_31384250_+SINEAluAluSz
CAediting_742413chr10_31384252_+SINEAluAluSz
CAediting_742416chr10_31410153_+LINEL1L1PA7
CAediting_742417chr10_31429467_+LINEL1L1PA13
CAediting_742418chr10_31429470_+LINEL1L1PA13
CAediting_742419chr10_31429474_+LINEL1L1PA13
CAediting_742420chr10_31429477_+LINEL1L1PA13
CAediting_742421chr10_31429478_+LINEL1L1PA13
CAediting_742422chr10_31432410_+SINEAluAluJb
CAediting_742423chr10_31432424_+SINEAluAluJb
CAediting_742424chr10_31432495_+SINEAluAluJb
CAediting_742425chr10_31442469_+LINEL1L1PA5
CAediting_742426chr10_31464273_+SINEAluAluYc
CAediting_742427chr10_31464274_+SINEAluAluYc
CAediting_742428chr10_31464323_+SINEAluAluYc
CAediting_742429chr10_31464341_+SINEAluAluYc
CAediting_742430chr10_31465638_+SINEAluAluJr4
CAediting_742431chr10_31465662_+SINEAluAluJr4
CAediting_742432chr10_31465683_+SINEAluAluJr4
CAediting_742433chr10_31465714_+SINEAluAluJr4
CAediting_742434chr10_31465747_+SINEAluAluJr4

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RNA A-to-I editing events in the alternative splicing sites for ZEB1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000148516.20.ZEB1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000148516.20.ZEB1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ZEB1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ZEB1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ZEB1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_742414chr10_31387263_+ENSG00000148516.20ENST00000437844hsa-miR-130331387257313872648mer-1a3138724231387264153-19.85

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688080chr9_63819626_+ENSG00000148516.20ENST00000437844hsa-miR-4477b31520798315208058mer-1a3152078231520805158-14.73
CAediting_524911chr7_5495852_-ENSG00000148516.20ENST00000320985hsa-miR-589-3p31528952315289587mer-m83152893331528959152-15.77
CAediting_524911chr7_5495852_-ENSG00000148516.20ENST00000361642hsa-miR-589-3p31528952315289587mer-m83152893331528959152-15.77
CAediting_414656chr5_72878640_+ENSG00000148516.20ENST00000437844hsa-miR-4804-3p31527187315271948mer-1a3152717231527194159-21.53
CAediting_524911chr7_5495852_-ENSG00000148516.20ENST00000437844hsa-miR-589-3p31528952315289587mer-m83152893331528959152-15.77
CAediting_524911chr7_5495852_-ENSG00000148516.20ENST00000446923hsa-miR-589-3p31528952315289587mer-m83152893331528959152-15.77
CAediting_468389chr6_31355314_-ENSG00000148516.20ENST00000437844hsa-miR-6891-5p31521006315210127mer-m83152099531521013153-26.33

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000320985hsa-miR-200b-3p31527632315276398mer-1a3152761731527639143-11.49
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000320985hsa-miR-200b-3p31527726315277327mer-m83152771231527733140-10.88
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000320985hsa-miR-200b-3p31528155315281617mer-m83152814431528162146-11.4
CAediting_228905chr2_188297554_+ENSG00000148516.20ENST00000320985hsa-miR-561-3p31528622315286287mer-m83152860831528629144-5.18
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000320985hsa-miR-64131528560315285667mer-m83152854431528567153-12.02
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000320985hsa-miR-64131528639315286457mer-1a3152862131528645140-11.61
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000320985hsa-miR-64131527866315278738mer-1a3152784531527873146-10.88
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000361642hsa-miR-200b-3p31527632315276398mer-1a3152761731527639143-11.49
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000361642hsa-miR-200b-3p31527726315277327mer-m83152771231527733140-10.88
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000361642hsa-miR-200b-3p31528155315281617mer-m83152814431528162146-11.4
CAediting_688080chr9_63819626_+ENSG00000148516.20ENST00000361642hsa-miR-4477b31529419315294257mer-m83152940631529426147-9.29
CAediting_228905chr2_188297554_+ENSG00000148516.20ENST00000361642hsa-miR-561-3p31528622315286287mer-m83152860831528629144-5.18
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000361642hsa-miR-64131528560315285667mer-m83152854431528567153-12.02
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000361642hsa-miR-64131528639315286457mer-1a3152862131528645140-11.61
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000361642hsa-miR-64131527866315278738mer-1a3152784531527873146-10.88
CAediting_396018chr5_1062918_-ENSG00000148516.20ENST00000437844hsa-miR-463531520343315203508mer-1a3152033031520350140-10.25
CAediting_396018chr5_1062918_-ENSG00000148516.20ENST00000437844hsa-miR-463531520787315207937mer-m83152077431520794145-11.71
CAediting_1399425chr20_1392958_-ENSG00000148516.20ENST00000437844hsa-miR-6869-5p31521866315218738mer-1a3152185231521873147-16.37
CAediting_1399425chr20_1392958_-ENSG00000148516.20ENST00000437844hsa-miR-6869-5p31520998315210047mer-m83152098431521005140-14.99
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000437844hsa-miR-200b-3p31527726315277327mer-m83152771231527733140-10.88
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000437844hsa-miR-200b-3p31528155315281617mer-m83152814431528162146-11.4
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000437844hsa-miR-200b-3p31527632315276398mer-1a3152761731527639143-11.49
CAediting_688080chr9_63819626_+ENSG00000148516.20ENST00000437844hsa-miR-4477b31529419315294257mer-m83152940631529426147-9.29
CAediting_228905chr2_188297554_+ENSG00000148516.20ENST00000437844hsa-miR-561-3p31528622315286287mer-m83152860831528629144-5.18
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000437844hsa-miR-64131527866315278738mer-1a3152784531527873146-10.88
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000437844hsa-miR-64131528560315285667mer-m83152854431528567153-12.02
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000437844hsa-miR-64131528639315286457mer-1a3152862131528645140-11.61
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000446923hsa-miR-200b-3p31527632315276398mer-1a3152761731527639143-11.49
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000446923hsa-miR-200b-3p31527726315277327mer-m83152771231527733140-10.88
CAediting_393chr1_1167164_+ENSG00000148516.20ENST00000446923hsa-miR-200b-3p31528155315281617mer-m83152814431528162146-11.4
CAediting_688080chr9_63819626_+ENSG00000148516.20ENST00000446923hsa-miR-4477b31529419315294257mer-m83152940631529426147-9.29
CAediting_228905chr2_188297554_+ENSG00000148516.20ENST00000446923hsa-miR-561-3p31528622315286287mer-m83152860831528629144-5.18
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000446923hsa-miR-64131528560315285667mer-m83152854431528567153-12.02
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000446923hsa-miR-64131528639315286457mer-1a3152862131528645140-11.61
CAediting_1351755chr19_40282625_-ENSG00000148516.20ENST00000446923hsa-miR-64131527866315278738mer-1a3152784531527873146-10.88

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ZEB1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ZEB1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ZEB1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ZEB1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ZEB1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ZEB1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
ZEB1C2750448CORNEAL DYSTROPHY, FUCHS ENDOTHELIAL, 64CTD_human;GENOMICS_ENGLAND;UNIPROT
ZEB1C0006142Malignant neoplasm of breast2CTD_human
ZEB1C0339284Polymorphous corneal dystrophy2ORPHANET
ZEB1C0678222Breast Carcinoma2CTD_human
ZEB1C1257931Mammary Neoplasms, Human2CTD_human
ZEB1C1458155Mammary Neoplasms2CTD_human
ZEB1C1836724CORNEAL DYSTROPHY, POSTERIOR POLYMORPHOUS, 3 (disorder)2CTD_human;GENOMICS_ENGLAND
ZEB1C4704874Mammary Carcinoma, Human2CTD_human
ZEB1C0007621Neoplastic Cell Transformation1CTD_human
ZEB1C0014170Endometrial Neoplasms1CTD_human
ZEB1C0016781Fuchs Endothelial Dystrophy1GENOMICS_ENGLAND;ORPHANET
ZEB1C0027626Neoplasm Invasiveness1CTD_human
ZEB1C0029172Oral Submucous Fibrosis1CTD_human
ZEB1C0036920Sezary Syndrome1CTD_human
ZEB1C0079773Lymphoma, T-Cell, Cutaneous1CTD_human
ZEB1C0151744Myocardial Ischemia1CTD_human
ZEB1C0235874Disease Exacerbation1CTD_human
ZEB1C0238463Papillary thyroid carcinoma1CTD_human
ZEB1C0376407Granulomatous Slack Skin1CTD_human
ZEB1C0476089Endometrial Carcinoma1CTD_human
ZEB1C0919267ovarian neoplasm1CTD_human
ZEB1C1140680Malignant neoplasm of ovary1CTD_human
ZEB1C3501843Nonmedullary Thyroid Carcinoma1CTD_human
ZEB1C3501844Familial Nonmedullary Thyroid Cancer1CTD_human