![]() |
||||||
|
![]() | |
![]() | |
![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
![]() | |
![]() | |
![]() | The effects of the RNA editing to the stability of the RNA structures |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Editing gene: SSR4 (CAeditome ID:6748) |
Gene summary for SSR4 |
![]() |
Gene information | Gene symbol | SSR4 | Gene ID | 6748 |
Gene name | signal sequence receptor subunit 4 | |
Synonyms | CDG1Y|TRAPD | |
Cytomap | Xq28 | |
Type of gene | protein-coding | |
Description | translocon-associated protein subunit deltaSSR-deltaTRAP-deltasignal sequence receptor, delta | |
Modification date | 20210518 | |
UniProtAcc | P51571 | |
Context |
![]() |
Gene | GO ID | GO term | PubMed ID |
SSR4 | GO:0005783 | Translocon-associated protein subunit delta | 0000052 |
Top |
RNA A-to-I events for SSR4 |
![]() |
![]() |
![]() |
![]() |
![]() |
CAediting_1527060(153795859, +), CAediting_1527061(153796960, +), |
Top |
RNA editing positional annotations for SSR4 using Annovar |
![]() |
CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
![]() |
CAeditome ID | Position | Variant type |
CAediting_1527060 | chrX_153795859_+ | ncRNA_exonic |
CAediting_1527061 | chrX_153796960_+ | ncRNA_exonic |
![]() |
CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_1527061 | chrX_153796960_+ | SINE | Alu | AluSx1 |
Top |
RNA A-to-I editing events in the alternative splicing sites for SSR4 |
![]() |
AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
ES | CAediting_1527060 | chrX_153795859_+ | 153795859:153795867 | 5SS | 3+0i | AAGGTCCTT | 1.62 | GAGGTCCTT | -0.02 |
IR | CAediting_1527060 | chrX_153795859_+ | 153795857:153795879 | 3SS | 0+18i | GCAAGGTCCTTTCTCTCACAGCT | -13.54 | GCGAGGTCCTTTCTCTCACAGCT | -13.06 |
IR | CAediting_1527060 | chrX_153795859_+ | 153795859:153795867 | 5SS | 3+0i | AAGGTCCTT | 1.62 | GAGGTCCTT | -0.02 |
MEX_1 | CAediting_1527060 | chrX_153795859_+ | 153795859:153795867 | 5SS | 3+0i | AAGGTCCTT | 1.62 | GAGGTCCTT | -0.02 |
![]() |
![]() |
![]() |
![]() |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for SSR4 |
![]() * The grey color means N/A. |
![]() |
![]() |
![]() |
![]() * Click on the image to enlarge it in a new window. |
OV.CAediting_1527060.ENSG00000180879.SSR4.png ![]() |
TGCT.CAediting_1527060.ENSG00000180879.SSR4.png ![]() |
Top |
Protein coding region RNA A-to-I editings for SSR4 |
![]() * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for SSR4 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
Top |
The effects of the RNA editing to the stability of the RNA structures for SSR4 |
![]() * Click on the image to enlarge it in a new window. |
ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
![]() |
CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for SSR4 |
![]() |
Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
BLCA | CAediting_1527060 | chrX_153795859_+ | . | . | 0.00747899767488789 | 0.162151007815115 | . | . |
LUSC | CAediting_1527060 | chrX_153795859_+ | . | . | . | . | 0.0415811527202739 | 0.0963168665352074 |
ESCA | CAediting_1527060 | chrX_153795859_+ | . | . | . | . | 0.0411215269023398 | 0.174105859141464 |
SKCM | CAediting_1527060 | chrX_153795859_+ | . | . | . | . | 0.0103414206028634 | 0.137693263579847 |
Top |
Relation with cancer stages for SSR4 |
![]() |
Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
KIRP | pathologic_stage | CAediting_1527060 | chrX_153795859_+ | 0.0362201140804544 | 0.174715233485589 |
STAD | pathologic_stage | CAediting_1527060 | chrX_153795859_+ | 0.0384359339353692 | -0.118801319317398 |
Top |
Relation with survival for SSR4 |
![]() |
Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
Top |
RelatedDrugs for SSR4 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for SSR4 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
SSR4 | C4012395 | Congenital disorder of glycosylation type 1y | 2 | CTD_human;GENOMICS_ENGLAND;ORPHANET |