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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: SMARCA1 (CAeditome ID:6594) |
Gene summary for SMARCA1 |
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Gene information | Gene symbol | SMARCA1 | Gene ID | 6594 |
Gene name | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | |
Synonyms | ISWI|NURF140|SNF2L|SNF2L1|SNF2LB|SNF2LT|SWI|SWI2|hSNF2L | |
Cytomap | Xq25-q26.1 | |
Type of gene | protein-coding | |
Description | probable global transcription activator SNF2L1ATP-dependent helicase SMARCA1SNF2-like 1global transcription activator homologous sequencenucleosome-remodeling factor subunit SNF2Lsucrose nonfermenting 2-like protein 1 | |
Modification date | 20210518 | |
UniProtAcc | P28370 | |
Context | - 31093468(Loss of Expression of a Novel Chromatin Remodeler SMARCA1 in Soft Tissue Sarcoma) |
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Gene | GO ID | GO term | PubMed ID |
SMARCA1 | GO:0043044 | Probable global transcription activator SNF2L1 | 15640247 |
SMARCA1 | GO:0008094 | Probable global transcription activator SNF2L1 | 14609955 |
SMARCA1 | GO:0070615 | Probable global transcription activator SNF2L1 | 15640247 |
SMARCA1 | GO:0036310 | Probable global transcription activator SNF2L1 | 22705370 |
SMARCA1 | GO:0006338 | Probable global transcription activator SNF2L1 | 14609955 |
SMARCA1 | GO:0005634 | Probable global transcription activator SNF2L1 | 14609955 |
SMARCA1 | GO:0005654 | Probable global transcription activator SNF2L1 | 0000052 |
SMARCA1 | GO:0043231 | Probable global transcription activator SNF2L1 | 0000052 |
SMARCA1 | GO:0016589 | Probable global transcription activator SNF2L1 | 20850016 |
SMARCA1 | GO:0090537 | Probable global transcription activator SNF2L1 | 15640247 |
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RNA A-to-I events for SMARCA1 |
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CAediting_1523275(129451739, -), CAediting_1523276(129451801, -), CAediting_1523277(129451842, -), CAediting_1523278(129451887, -), CAediting_1523279(129460529, -), CAediting_1523280(129463815, -), CAediting_1523281(129489032, -), CAediting_1523282(129511962, -), |
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RNA editing positional annotations for SMARCA1 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_1523281 | chrX_129489032_- | nonsynonymous SNV | ENST00000371121.4 | c.A2002G | p.M668V | D | B | D |
CAediting_1523281 | chrX_129489032_- | nonsynonymous SNV | ENST00000371122.7 | c.A2002G | p.M668V | D | B | D |
CAediting_1523281 | chrX_129489032_- | nonsynonymous SNV | ENST00000371123.4 | c.A1966G | p.M656V | D | B | D |
CAediting_1523282 | chrX_129511962_- | nonsynonymous SNV | ENST00000371121.4 | c.A652G | p.T218A | D | D | D |
CAediting_1523282 | chrX_129511962_- | nonsynonymous SNV | ENST00000371122.7 | c.A652G | p.T218A | D | D | D |
CAediting_1523282 | chrX_129511962_- | nonsynonymous SNV | ENST00000371123.4 | c.A652G | p.T218A | D | D | D |
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CAeditome ID | Position | Variant type |
CAediting_1523275 | chrX_129451739_- | ncRNA_intronic |
CAediting_1523276 | chrX_129451801_- | ncRNA_intronic |
CAediting_1523277 | chrX_129451842_- | ncRNA_intronic |
CAediting_1523278 | chrX_129451887_- | ncRNA_intronic |
CAediting_1523279 | chrX_129460529_- | ncRNA_intronic |
CAediting_1523280 | chrX_129463815_- | ncRNA_intronic |
CAediting_1523281 | chrX_129489032_- | exonic |
CAediting_1523282 | chrX_129511962_- | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_1523275 | chrX_129451739_- | SINE | Alu | AluY |
CAediting_1523276 | chrX_129451801_- | SINE | Alu | AluY |
CAediting_1523277 | chrX_129451842_- | SINE | Alu | AluY |
CAediting_1523278 | chrX_129451887_- | SINE | Alu | AluY |
CAediting_1523279 | chrX_129460529_- | SINE | Alu | AluSz |
CAediting_1523280 | chrX_129463815_- | SINE | Alu | AluSq2 |
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RNA A-to-I editing events in the alternative splicing sites for SMARCA1 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SMARCA1 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for SMARCA1 |
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The effects of the RNA editing to the miRNA binding sites for SMARCA1 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for SMARCA1 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for SMARCA1 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for SMARCA1 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for SMARCA1 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for SMARCA1 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SMARCA1 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
SMARCA1 | C0265338 | Coffin-Siris syndrome | 2 | CLINGEN;GENOMICS_ENGLAND |
SMARCA1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
SMARCA1 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |