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Editing gene: MRPS15 (CAeditome ID:64960)

Gene summary for MRPS15

Gene summary

Gene information	Gene symbol	MRPS15
	Gene ID	64960
	Gene name	mitochondrial ribosomal protein S15
	Synonyms	DC37\|MPR-S15\|RPMS15\|S15mt
	Cytomap	1p34.3
	Type of gene	protein-coding
	Description	28S ribosomal protein S15, mitochondrialMRP-S15mitochondrial small ribosomal subunit protein uS15m
	Modification date	20210518
	UniProtAcc	P82914
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
MRPS15	GO:0005654	28S ribosomal protein S15, mitochondrial	0000052
MRPS15	GO:0005730	28S ribosomal protein S15, mitochondrial	0000052
MRPS15	GO:0005739	28S ribosomal protein S15, mitochondrial	0000052
MRPS15	GO:0005763	28S ribosomal protein S15, mitochondrial	11279123
MRPS15	GO:0005763	28S ribosomal protein S15, mitochondrial	25838379

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RNA A-to-I events for MRPS15

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000116898.10

RNA A-to-I editing events in Cancer.

CAediting_46682(36457032, -), CAediting_46683(36457214, -), CAediting_46684(36458325, -), CAediting_46685(36458331, -), CAediting_46686(36458339, -), CAediting_46687(36458340, -), CAediting_46688(36458366, -), CAediting_46689(36458367, -), CAediting_46690(36458393, -), CAediting_46691(36458396, -), CAediting_46692(36458397, -), CAediting_46693(36458422, -), CAediting_46694(36458423, -), CAediting_46695(36458430, -), CAediting_46696(36458456, -), CAediting_46697(36458461, -), CAediting_46698(36458479, -), CAediting_46699(36458501, -), CAediting_46700(36458508, -), CAediting_46701(36458524, -), CAediting_46702(36459131, -), CAediting_46703(36459137, -), CAediting_46704(36459149, -), CAediting_46705(36459172, -), CAediting_46706(36459173, -), CAediting_46707(36459176, -), CAediting_46708(36459177, -), CAediting_46709(36459182, -), CAediting_46710(36459196, -), CAediting_46711(36459209, -), CAediting_46712(36459219, -), CAediting_46713(36459222, -), CAediting_46714(36459224, -), CAediting_46715(36459245, -), CAediting_46716(36459246, -), CAediting_46717(36459250, -), CAediting_46718(36459251, -), CAediting_46719(36459259, -), CAediting_46720(36459282, -), CAediting_46721(36459299, -), CAediting_46722(36459367, -), CAediting_46723(36459379, -), CAediting_46724(36459387, -), CAediting_46725(36460107, -), CAediting_46726(36460122, -), CAediting_46727(36460146, -), CAediting_46728(36460172, -), CAediting_46729(36460177, -), CAediting_46730(36460179, -), CAediting_46731(36460186, -), CAediting_46732(36460228, -), CAediting_46733(36460256, -), CAediting_46734(36460301, -),

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RNA editing positional annotations for MRPS15 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_46682	chr1_36457032_-	ncRNA_intronic
CAediting_46683	chr1_36457214_-	ncRNA_intronic
CAediting_46684	chr1_36458325_-	ncRNA_exonic
CAediting_46685	chr1_36458331_-	ncRNA_exonic
CAediting_46686	chr1_36458339_-	ncRNA_exonic
CAediting_46687	chr1_36458340_-	ncRNA_exonic
CAediting_46688	chr1_36458366_-	ncRNA_exonic
CAediting_46689	chr1_36458367_-	ncRNA_exonic
CAediting_46690	chr1_36458393_-	ncRNA_exonic
CAediting_46691	chr1_36458396_-	ncRNA_exonic
CAediting_46692	chr1_36458397_-	ncRNA_exonic
CAediting_46693	chr1_36458422_-	ncRNA_exonic
CAediting_46694	chr1_36458423_-	ncRNA_exonic
CAediting_46695	chr1_36458430_-	ncRNA_exonic
CAediting_46696	chr1_36458456_-	ncRNA_exonic
CAediting_46697	chr1_36458461_-	ncRNA_exonic
CAediting_46698	chr1_36458479_-	ncRNA_exonic
CAediting_46699	chr1_36458501_-	ncRNA_exonic
CAediting_46700	chr1_36458508_-	ncRNA_exonic
CAediting_46701	chr1_36458524_-	ncRNA_exonic
CAediting_46702	chr1_36459131_-	ncRNA_exonic
CAediting_46703	chr1_36459137_-	ncRNA_exonic
CAediting_46704	chr1_36459149_-	ncRNA_exonic
CAediting_46705	chr1_36459172_-	ncRNA_exonic
CAediting_46706	chr1_36459173_-	ncRNA_exonic
CAediting_46707	chr1_36459176_-	ncRNA_exonic
CAediting_46708	chr1_36459177_-	ncRNA_exonic
CAediting_46709	chr1_36459182_-	ncRNA_exonic
CAediting_46710	chr1_36459196_-	ncRNA_exonic
CAediting_46711	chr1_36459209_-	ncRNA_exonic
CAediting_46712	chr1_36459219_-	ncRNA_exonic
CAediting_46713	chr1_36459222_-	ncRNA_exonic
CAediting_46714	chr1_36459224_-	ncRNA_exonic
CAediting_46715	chr1_36459245_-	ncRNA_exonic
CAediting_46716	chr1_36459246_-	ncRNA_exonic
CAediting_46717	chr1_36459250_-	ncRNA_exonic
CAediting_46718	chr1_36459251_-	ncRNA_exonic
CAediting_46719	chr1_36459259_-	ncRNA_exonic
CAediting_46720	chr1_36459282_-	ncRNA_exonic
CAediting_46721	chr1_36459299_-	ncRNA_exonic
CAediting_46722	chr1_36459367_-	ncRNA_exonic
CAediting_46723	chr1_36459379_-	ncRNA_exonic
CAediting_46724	chr1_36459387_-	ncRNA_exonic
CAediting_46725	chr1_36460107_-	ncRNA_intronic
CAediting_46726	chr1_36460122_-	ncRNA_intronic
CAediting_46727	chr1_36460146_-	ncRNA_intronic
CAediting_46728	chr1_36460172_-	ncRNA_intronic
CAediting_46729	chr1_36460177_-	ncRNA_intronic
CAediting_46730	chr1_36460179_-	ncRNA_intronic
CAediting_46731	chr1_36460186_-	ncRNA_intronic
CAediting_46732	chr1_36460228_-	ncRNA_intronic
CAediting_46733	chr1_36460256_-	ncRNA_intronic
CAediting_46734	chr1_36460301_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_46682	chr1_36457032_-	SINE	Alu	AluSc8
CAediting_46683	chr1_36457214_-	SINE	Alu	AluSc8
CAediting_46684	chr1_36458325_-	SINE	Alu	AluSx1
CAediting_46685	chr1_36458331_-	SINE	Alu	AluSx1
CAediting_46686	chr1_36458339_-	SINE	Alu	AluSx1
CAediting_46687	chr1_36458340_-	SINE	Alu	AluSx1
CAediting_46688	chr1_36458366_-	SINE	Alu	AluSx1
CAediting_46689	chr1_36458367_-	SINE	Alu	AluSx1
CAediting_46690	chr1_36458393_-	SINE	Alu	AluSx1
CAediting_46691	chr1_36458396_-	SINE	Alu	AluSx1
CAediting_46692	chr1_36458397_-	SINE	Alu	AluSx1
CAediting_46693	chr1_36458422_-	SINE	Alu	AluSx1
CAediting_46694	chr1_36458423_-	SINE	Alu	AluSx1
CAediting_46695	chr1_36458430_-	SINE	Alu	AluSx1
CAediting_46696	chr1_36458456_-	SINE	Alu	AluSx1
CAediting_46697	chr1_36458461_-	SINE	Alu	AluSx1
CAediting_46698	chr1_36458479_-	SINE	Alu	AluSx1
CAediting_46699	chr1_36458501_-	SINE	Alu	AluSx1
CAediting_46700	chr1_36458508_-	SINE	Alu	AluSx1
CAediting_46701	chr1_36458524_-	SINE	Alu	AluSx1
CAediting_46702	chr1_36459131_-	SINE	Alu	AluJb
CAediting_46703	chr1_36459137_-	SINE	Alu	AluJb
CAediting_46704	chr1_36459149_-	SINE	Alu	AluJb
CAediting_46705	chr1_36459172_-	SINE	Alu	AluJb
CAediting_46706	chr1_36459173_-	SINE	Alu	AluJb
CAediting_46707	chr1_36459176_-	SINE	Alu	AluJb
CAediting_46708	chr1_36459177_-	SINE	Alu	AluJb
CAediting_46709	chr1_36459182_-	SINE	Alu	AluJb
CAediting_46710	chr1_36459196_-	SINE	Alu	AluJb
CAediting_46711	chr1_36459209_-	SINE	Alu	AluJb
CAediting_46712	chr1_36459219_-	SINE	Alu	AluJb
CAediting_46713	chr1_36459222_-	SINE	Alu	AluJb
CAediting_46714	chr1_36459224_-	SINE	Alu	AluJb
CAediting_46715	chr1_36459245_-	SINE	Alu	AluJb
CAediting_46716	chr1_36459246_-	SINE	Alu	AluJb
CAediting_46717	chr1_36459250_-	SINE	Alu	AluJb
CAediting_46718	chr1_36459251_-	SINE	Alu	AluJb
CAediting_46719	chr1_36459259_-	SINE	Alu	AluJb
CAediting_46720	chr1_36459282_-	SINE	Alu	AluJb
CAediting_46721	chr1_36459299_-	SINE	Alu	AluJb
CAediting_46722	chr1_36459367_-	SINE	Alu	AluJb
CAediting_46723	chr1_36459379_-	SINE	Alu	AluJb
CAediting_46724	chr1_36459387_-	SINE	Alu	AluJb
CAediting_46725	chr1_36460107_-	SINE	Alu	AluY
CAediting_46726	chr1_36460122_-	SINE	Alu	AluY
CAediting_46727	chr1_36460146_-	SINE	Alu	AluY
CAediting_46728	chr1_36460172_-	SINE	Alu	AluY
CAediting_46729	chr1_36460177_-	SINE	Alu	AluY
CAediting_46730	chr1_36460179_-	SINE	Alu	AluY
CAediting_46731	chr1_36460186_-	SINE	Alu	AluY
CAediting_46732	chr1_36460228_-	SINE	Alu	AluY
CAediting_46733	chr1_36460256_-	SINE	Alu	AluY
CAediting_46734	chr1_36460301_-	SINE	Alu	AluY

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RNA A-to-I editing events in the alternative splicing sites for MRPS15

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000116898.10.MRPS15.

Correlation between RNA A-to-I editing and PSI for ENSG00000116898.10.MRPS15.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRPS15

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MRPS15

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for MRPS15

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MRPS15

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000462067.1	processed_transcript
ENST00000488606.4	processed_transcript

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_46684	ENST00000462067.1	chr1_36458325_-	-526.00	-523.20	-544.40
CAediting_46685	ENST00000462067.1	chr1_36458331_-	-526.30	-523.20	-544.40
CAediting_46686	ENST00000462067.1	chr1_36458339_-	-526.20	-523.20	-544.40
CAediting_46687	ENST00000462067.1	chr1_36458340_-	-525.10	-523.20	-544.40
CAediting_46688	ENST00000462067.1	chr1_36458366_-	-523.20	-523.20	-544.40
CAediting_46689	ENST00000462067.1	chr1_36458367_-	-523.70	-523.20	-544.40
CAediting_46690	ENST00000462067.1	chr1_36458393_-	-523.20	-523.20	-544.40
CAediting_46691	ENST00000462067.1	chr1_36458396_-	-523.20	-523.20	-544.40
CAediting_46692	ENST00000462067.1	chr1_36458397_-	-523.20	-523.20	-544.40
CAediting_46693	ENST00000462067.1	chr1_36458422_-	-523.90	-523.20	-544.40
CAediting_46694	ENST00000462067.1	chr1_36458423_-	-524.60	-523.20	-544.40
CAediting_46695	ENST00000462067.1	chr1_36458430_-	-522.50	-523.20	-544.40
CAediting_46696	ENST00000462067.1	chr1_36458456_-	-523.00	-523.20	-544.40
CAediting_46697	ENST00000462067.1	chr1_36458461_-	-525.60	-523.20	-544.40
CAediting_46698	ENST00000462067.1	chr1_36458479_-	-522.80	-523.20	-544.40
CAediting_46699	ENST00000462067.1	chr1_36458501_-	-524.20	-523.20	-544.40
CAediting_46700	ENST00000462067.1	chr1_36458508_-	-524.00	-523.20	-544.40
CAediting_46701	ENST00000462067.1	chr1_36458524_-	-522.50	-523.20	-544.40
CAediting_46684	ENST00000488606.4	chr1_36458325_-	-829.30	-822.60	-905.60
CAediting_46685	ENST00000488606.4	chr1_36458331_-	-826.20	-822.60	-905.60
CAediting_46686	ENST00000488606.4	chr1_36458339_-	-828.80	-822.60	-905.60
CAediting_46687	ENST00000488606.4	chr1_36458340_-	-822.60	-822.60	-905.60
CAediting_46688	ENST00000488606.4	chr1_36458366_-	-825.80	-822.60	-905.60
CAediting_46689	ENST00000488606.4	chr1_36458367_-	-824.30	-822.60	-905.60
CAediting_46690	ENST00000488606.4	chr1_36458393_-	-822.30	-822.60	-905.60
CAediting_46691	ENST00000488606.4	chr1_36458396_-	-822.60	-822.60	-905.60
CAediting_46692	ENST00000488606.4	chr1_36458397_-	-822.70	-822.60	-905.60
CAediting_46693	ENST00000488606.4	chr1_36458422_-	-822.30	-822.60	-905.60
CAediting_46694	ENST00000488606.4	chr1_36458423_-	-822.70	-822.60	-905.60
CAediting_46695	ENST00000488606.4	chr1_36458430_-	-822.90	-822.60	-905.60
CAediting_46696	ENST00000488606.4	chr1_36458456_-	-821.90	-822.60	-905.60
CAediting_46697	ENST00000488606.4	chr1_36458461_-	-821.70	-822.60	-905.60
CAediting_46698	ENST00000488606.4	chr1_36458479_-	-822.20	-822.60	-905.60
CAediting_46699	ENST00000488606.4	chr1_36458501_-	-822.30	-822.60	-905.60
CAediting_46700	ENST00000488606.4	chr1_36458508_-	-826.40	-822.60	-905.60
CAediting_46701	ENST00000488606.4	chr1_36458524_-	-826.50	-822.60	-905.60
CAediting_46702	ENST00000488606.4	chr1_36459131_-	-826.80	-822.60	-905.60
CAediting_46703	ENST00000488606.4	chr1_36459137_-	-822.60	-822.60	-905.60
CAediting_46704	ENST00000488606.4	chr1_36459149_-	-822.30	-822.60	-905.60
CAediting_46705	ENST00000488606.4	chr1_36459172_-	-822.90	-822.60	-905.60
CAediting_46706	ENST00000488606.4	chr1_36459173_-	-829.00	-822.60	-905.60
CAediting_46707	ENST00000488606.4	chr1_36459176_-	-822.30	-822.60	-905.60
CAediting_46708	ENST00000488606.4	chr1_36459177_-	-822.30	-822.60	-905.60
CAediting_46709	ENST00000488606.4	chr1_36459182_-	-821.70	-822.60	-905.60
CAediting_46710	ENST00000488606.4	chr1_36459196_-	-829.30	-822.60	-905.60
CAediting_46711	ENST00000488606.4	chr1_36459209_-	-828.80	-822.60	-905.60
CAediting_46712	ENST00000488606.4	chr1_36459219_-	-829.30	-822.60	-905.60
CAediting_46713	ENST00000488606.4	chr1_36459222_-	-828.80	-822.60	-905.60
CAediting_46714	ENST00000488606.4	chr1_36459224_-	-822.00	-822.60	-905.60
CAediting_46715	ENST00000488606.4	chr1_36459245_-	-822.60	-822.60	-905.60
CAediting_46716	ENST00000488606.4	chr1_36459246_-	-822.70	-822.60	-905.60
CAediting_46717	ENST00000488606.4	chr1_36459250_-	-827.20	-822.60	-905.60
CAediting_46718	ENST00000488606.4	chr1_36459251_-	-824.50	-822.60	-905.60
CAediting_46719	ENST00000488606.4	chr1_36459259_-	-822.90	-822.60	-905.60
CAediting_46720	ENST00000488606.4	chr1_36459282_-	-821.30	-822.60	-905.60
CAediting_46721	ENST00000488606.4	chr1_36459299_-	-828.90	-822.60	-905.60
CAediting_46722	ENST00000488606.4	chr1_36459367_-	-828.80	-822.60	-905.60
CAediting_46723	ENST00000488606.4	chr1_36459379_-	-826.20	-822.60	-905.60
CAediting_46724	ENST00000488606.4	chr1_36459387_-	-828.00	-822.60	-905.60

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Relation with ADAR for MRPS15

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for MRPS15

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for MRPS15

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for MRPS15

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for MRPS15

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene