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Editing gene: RFX7 (CAeditome ID:64864)

Gene summary for RFX7

Gene summary

Gene information	Gene symbol	RFX7
	Gene ID	64864
	Gene name	regulatory factor X7
	Synonyms	RFXDC2
	Cytomap	15q21.3
	Type of gene	protein-coding
	Description	DNA-binding protein RFX7regulatory factor X domain containing 2regulatory factor X domain-containing protein 2regulatory factor X, 7
	Modification date	20210518
	UniProtAcc	Q2KHR2
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
RFX7	GO:1990837	DNA-binding protein RFX7	28473536

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RNA A-to-I events for RFX7

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000181827.13

RNA A-to-I editing events in Cancer.

CAediting_1043022(56094057, -), CAediting_1043023(56094064, -), CAediting_1043024(56114364, -), CAediting_1043025(56115749, -), CAediting_1043026(56115782, -), CAediting_1043027(56115820, -), CAediting_1043028(56115825, -), CAediting_1043029(56115830, -), CAediting_1043030(56115898, -), CAediting_1043031(56115904, -), CAediting_1043032(56117839, -), CAediting_1043033(56117841, -), CAediting_1043034(56117856, -), CAediting_1043035(56117896, -), CAediting_1043036(56118628, -), CAediting_1043037(56118629, -), CAediting_1043038(56118893, -), CAediting_1043039(56131360, -), CAediting_1043040(56131382, -), CAediting_1043041(56131399, -), CAediting_1043042(56147742, -), CAediting_1043043(56158812, -), CAediting_1043044(56166821, -), CAediting_1043045(56166846, -), CAediting_1043046(56167261, -), CAediting_1043047(56167263, -), CAediting_1043048(56167275, -), CAediting_1043049(56184221, -), CAediting_1043050(56184232, -), CAediting_1043051(56184242, -), CAediting_1043052(56184306, -), CAediting_1043053(56184311, -), CAediting_1043054(56184318, -), CAediting_1043055(56184328, -), CAediting_1043056(56187335, -), CAediting_1043057(56187348, -), CAediting_1043058(56187362, -), CAediting_1043059(56187371, -), CAediting_1043060(56187404, -), CAediting_1043061(56187410, -), CAediting_1043062(56187412, -), CAediting_1043063(56187438, -), CAediting_1043064(56188929, -), CAediting_1043065(56189215, -), CAediting_1043066(56189279, -), CAediting_1043067(56189323, -), CAediting_1043068(56202569, -), CAediting_1043069(56202601, -), CAediting_1043070(56202612, -), CAediting_1043071(56202632, -), CAediting_1043072(56202649, -), CAediting_1043073(56202687, -), CAediting_1043074(56202729, -), CAediting_1043075(56202760, -), CAediting_1043076(56204099, -), CAediting_1043077(56204117, -), CAediting_1043078(56204157, -), CAediting_1043079(56204158, -), CAediting_1043080(56204179, -), CAediting_1043081(56204180, -), CAediting_1043082(56204184, -), CAediting_1043083(56204294, -), CAediting_1043084(56218184, -), CAediting_1043085(56218222, -), CAediting_1043086(56218251, -), CAediting_1043087(56218303, -), CAediting_1043088(56218335, -), CAediting_1043089(56218336, -), CAediting_1043090(56218374, -), CAediting_1043091(56229468, -), CAediting_1043092(56229470, -), CAediting_1043093(56230905, -), CAediting_1043094(56230915, -), CAediting_1043095(56230966, -), CAediting_1043096(56230974, -), CAediting_1043097(56230976, -), CAediting_1043098(56230986, -), CAediting_1043099(56239562, -),

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RNA editing positional annotations for RFX7 using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_1043023	chr15_56094064_-	nonsynonymous SNV	ENST00000559447.5	c.A3373G	p.R1125G	D	D	D
CAediting_1043023	chr15_56094064_-	nonsynonymous SNV	ENST00000559847.5	c.A3373G	p.R1125G	D	D	D

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1043022	chr15_56094057_-	exonic
CAediting_1043023	chr15_56094064_-	exonic
CAediting_1043024	chr15_56114364_-	intronic
CAediting_1043025	chr15_56115749_-	intronic
CAediting_1043026	chr15_56115782_-	intronic
CAediting_1043027	chr15_56115820_-	intronic
CAediting_1043028	chr15_56115825_-	intronic
CAediting_1043029	chr15_56115830_-	intronic
CAediting_1043030	chr15_56115898_-	intronic
CAediting_1043031	chr15_56115904_-	intronic
CAediting_1043032	chr15_56117839_-	intronic
CAediting_1043033	chr15_56117841_-	intronic
CAediting_1043034	chr15_56117856_-	intronic
CAediting_1043035	chr15_56117896_-	intronic
CAediting_1043036	chr15_56118628_-	intronic
CAediting_1043037	chr15_56118629_-	intronic
CAediting_1043038	chr15_56118893_-	intronic
CAediting_1043039	chr15_56131360_-	intronic
CAediting_1043040	chr15_56131382_-	intronic
CAediting_1043041	chr15_56131399_-	intronic
CAediting_1043042	chr15_56147742_-	intronic
CAediting_1043043	chr15_56158812_-	intronic
CAediting_1043044	chr15_56166821_-	intronic
CAediting_1043045	chr15_56166846_-	intronic
CAediting_1043046	chr15_56167261_-	intronic
CAediting_1043047	chr15_56167263_-	intronic
CAediting_1043048	chr15_56167275_-	intronic
CAediting_1043049	chr15_56184221_-	intronic
CAediting_1043050	chr15_56184232_-	intronic
CAediting_1043051	chr15_56184242_-	intronic
CAediting_1043052	chr15_56184306_-	intronic
CAediting_1043053	chr15_56184311_-	intronic
CAediting_1043054	chr15_56184318_-	intronic
CAediting_1043055	chr15_56184328_-	intronic
CAediting_1043056	chr15_56187335_-	intronic
CAediting_1043057	chr15_56187348_-	intronic
CAediting_1043058	chr15_56187362_-	intronic
CAediting_1043059	chr15_56187371_-	intronic
CAediting_1043060	chr15_56187404_-	intronic
CAediting_1043061	chr15_56187410_-	intronic
CAediting_1043062	chr15_56187412_-	intronic
CAediting_1043063	chr15_56187438_-	intronic
CAediting_1043064	chr15_56188929_-	intronic
CAediting_1043065	chr15_56189215_-	intronic
CAediting_1043066	chr15_56189279_-	intronic
CAediting_1043067	chr15_56189323_-	intronic
CAediting_1043068	chr15_56202569_-	intronic
CAediting_1043069	chr15_56202601_-	intronic
CAediting_1043070	chr15_56202612_-	intronic
CAediting_1043071	chr15_56202632_-	intronic
CAediting_1043072	chr15_56202649_-	intronic
CAediting_1043073	chr15_56202687_-	intronic
CAediting_1043074	chr15_56202729_-	intronic
CAediting_1043075	chr15_56202760_-	intronic
CAediting_1043076	chr15_56204099_-	intronic
CAediting_1043077	chr15_56204117_-	intronic
CAediting_1043078	chr15_56204157_-	intronic
CAediting_1043079	chr15_56204158_-	intronic
CAediting_1043080	chr15_56204179_-	intronic
CAediting_1043081	chr15_56204180_-	intronic
CAediting_1043082	chr15_56204184_-	intronic
CAediting_1043083	chr15_56204294_-	intronic
CAediting_1043084	chr15_56218184_-	intronic
CAediting_1043085	chr15_56218222_-	intronic
CAediting_1043086	chr15_56218251_-	intronic
CAediting_1043087	chr15_56218303_-	intronic
CAediting_1043088	chr15_56218335_-	intronic
CAediting_1043089	chr15_56218336_-	intronic
CAediting_1043090	chr15_56218374_-	intronic
CAediting_1043091	chr15_56229468_-	intronic
CAediting_1043092	chr15_56229470_-	intronic
CAediting_1043093	chr15_56230905_-	intronic
CAediting_1043094	chr15_56230915_-	intronic
CAediting_1043095	chr15_56230966_-	intronic
CAediting_1043096	chr15_56230974_-	intronic
CAediting_1043097	chr15_56230976_-	intronic
CAediting_1043098	chr15_56230986_-	intronic
CAediting_1043099	chr15_56239562_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1043024	chr15_56114364_-	SINE	Alu	AluSx1
CAediting_1043025	chr15_56115749_-	SINE	Alu	AluYm1
CAediting_1043026	chr15_56115782_-	SINE	Alu	AluYm1
CAediting_1043027	chr15_56115820_-	SINE	Alu	AluYm1
CAediting_1043028	chr15_56115825_-	SINE	Alu	AluYm1
CAediting_1043029	chr15_56115830_-	SINE	Alu	AluYm1
CAediting_1043030	chr15_56115898_-	SINE	Alu	AluYm1
CAediting_1043031	chr15_56115904_-	SINE	Alu	AluYm1
CAediting_1043032	chr15_56117839_-	LINE	L1	L1MA5A
CAediting_1043033	chr15_56117841_-	LINE	L1	L1MA5A
CAediting_1043034	chr15_56117856_-	LINE	L1	L1MA5A
CAediting_1043035	chr15_56117896_-	LINE	L1	L1MA5A
CAediting_1043036	chr15_56118628_-	LINE	L1	L1MA3
CAediting_1043037	chr15_56118629_-	LINE	L1	L1MA3
CAediting_1043038	chr15_56118893_-	LINE	L1	L1MA3
CAediting_1043039	chr15_56131360_-	SINE	Alu	AluJr
CAediting_1043040	chr15_56131382_-	SINE	Alu	AluJr
CAediting_1043041	chr15_56131399_-	SINE	Alu	AluJr
CAediting_1043042	chr15_56147742_-	SINE	Alu	AluYj4
CAediting_1043043	chr15_56158812_-	SINE	Alu	AluJb
CAediting_1043044	chr15_56166821_-	SINE	Alu	FRAM
CAediting_1043045	chr15_56166846_-	SINE	Alu	FRAM
CAediting_1043046	chr15_56167261_-	SINE	Alu	AluJo
CAediting_1043047	chr15_56167263_-	SINE	Alu	AluJo
CAediting_1043048	chr15_56167275_-	SINE	Alu	AluJo
CAediting_1043049	chr15_56184221_-	SINE	Alu	AluSp
CAediting_1043050	chr15_56184232_-	SINE	Alu	AluSp
CAediting_1043051	chr15_56184242_-	SINE	Alu	AluSp
CAediting_1043052	chr15_56184306_-	SINE	Alu	AluSp
CAediting_1043053	chr15_56184311_-	SINE	Alu	AluSp
CAediting_1043054	chr15_56184318_-	SINE	Alu	AluSp
CAediting_1043055	chr15_56184328_-	SINE	Alu	AluSp
CAediting_1043056	chr15_56187335_-	SINE	Alu	AluSz
CAediting_1043057	chr15_56187348_-	SINE	Alu	AluSz
CAediting_1043058	chr15_56187362_-	SINE	Alu	AluSz
CAediting_1043059	chr15_56187371_-	SINE	Alu	AluSz
CAediting_1043060	chr15_56187404_-	SINE	Alu	AluSz
CAediting_1043061	chr15_56187410_-	SINE	Alu	AluSz
CAediting_1043062	chr15_56187412_-	SINE	Alu	AluSz
CAediting_1043063	chr15_56187438_-	SINE	Alu	AluSz
CAediting_1043064	chr15_56188929_-	SINE	Alu	AluSx
CAediting_1043065	chr15_56189215_-	SINE	Alu	AluJr4
CAediting_1043066	chr15_56189279_-	SINE	Alu	AluJr4
CAediting_1043067	chr15_56189323_-	SINE	Alu	AluJr4
CAediting_1043068	chr15_56202569_-	SINE	Alu	AluJr
CAediting_1043069	chr15_56202601_-	SINE	Alu	AluJr
CAediting_1043070	chr15_56202612_-	SINE	Alu	AluJr
CAediting_1043071	chr15_56202632_-	SINE	Alu	AluJr
CAediting_1043072	chr15_56202649_-	SINE	Alu	AluJr
CAediting_1043073	chr15_56202687_-	SINE	Alu	AluJr
CAediting_1043074	chr15_56202729_-	SINE	Alu	AluJr
CAediting_1043075	chr15_56202760_-	SINE	Alu	AluJr
CAediting_1043076	chr15_56204099_-	SINE	Alu	AluSz
CAediting_1043077	chr15_56204117_-	SINE	Alu	AluSz
CAediting_1043078	chr15_56204157_-	SINE	Alu	AluSz
CAediting_1043079	chr15_56204158_-	SINE	Alu	AluSz
CAediting_1043080	chr15_56204179_-	SINE	Alu	AluSz
CAediting_1043081	chr15_56204180_-	SINE	Alu	AluSz
CAediting_1043082	chr15_56204184_-	SINE	Alu	AluSz
CAediting_1043083	chr15_56204294_-	SINE	Alu	AluSz
CAediting_1043084	chr15_56218184_-	SINE	Alu	AluSq2
CAediting_1043085	chr15_56218222_-	SINE	Alu	AluSq2
CAediting_1043086	chr15_56218251_-	SINE	Alu	AluSq2
CAediting_1043087	chr15_56218303_-	SINE	Alu	AluSq2
CAediting_1043088	chr15_56218335_-	SINE	Alu	AluSq2
CAediting_1043089	chr15_56218336_-	SINE	Alu	AluSq2
CAediting_1043090	chr15_56218374_-	SINE	Alu	AluSq2
CAediting_1043091	chr15_56229468_-	SINE	Alu	AluY
CAediting_1043092	chr15_56229470_-	SINE	Alu	AluY
CAediting_1043093	chr15_56230905_-	SINE	Alu	AluY
CAediting_1043094	chr15_56230915_-	SINE	Alu	AluY
CAediting_1043095	chr15_56230966_-	SINE	Alu	AluY
CAediting_1043096	chr15_56230974_-	SINE	Alu	AluY
CAediting_1043097	chr15_56230976_-	SINE	Alu	AluY
CAediting_1043098	chr15_56230986_-	SINE	Alu	AluY
CAediting_1043099	chr15_56239562_-	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for RFX7

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000181827.13.RFX7.

Correlation between RNA A-to-I editing and PSI for ENSG00000181827.13.RFX7.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RFX7

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for RFX7

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for RFX7

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RFX7

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for RFX7

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for RFX7

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for RFX7

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for RFX7

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for RFX7

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
RFX7	C2931456	Prostate cancer, familial	1	CTD_human
RFX7	C4722327	PROSTATE CANCER, HEREDITARY, 1	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene