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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: MS4A6A (CAeditome ID:64231) |
Gene summary for MS4A6A |
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Gene information | Gene symbol | MS4A6A | Gene ID | 64231 |
Gene name | membrane spanning 4-domains A6A | |
Synonyms | 4SPAN3|4SPAN3.2|CD20L3|CDA01|MS4A6|MST090|MSTP090 | |
Cytomap | 11q12.2 | |
Type of gene | protein-coding | |
Description | membrane-spanning 4-domains subfamily A member 6ACD20 antigen-like 3CD20-like precusorHAIRB-isoMS4A6A-polymorphfour-span transmembrane protein 3four-span transmembrane protein 3.1four-span transmembrane protein 3.2membrane-spanning 4-domains, subf | |
Modification date | 20210518 | |
UniProtAcc | Q9H2W1 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
MS4A6A | GO:0005802 | Membrane-spanning 4-domains subfamily A member 6A | 23874341 |
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RNA A-to-I events for MS4A6A |
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CAediting_816129(60174520, -), CAediting_816130(60176104, -), |
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RNA editing positional annotations for MS4A6A using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_816129 | chr11_60174520_- | ncRNA_intronic |
CAediting_816130 | chr11_60176104_- | ncRNA_intronic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_816129 | chr11_60174520_- | SINE | Alu | AluSg7 |
CAediting_816130 | chr11_60176104_- | DNA | TcMar-Mariner | MADE1 |
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RNA A-to-I editing events in the alternative splicing sites for MS4A6A |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MS4A6A |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for MS4A6A |
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The effects of the RNA editing to the miRNA binding sites for MS4A6A |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_688080 | chr9_63819626_+ | ENSG00000110077.13 | ENST00000528851 | hsa-miR-4477b | 60172201 | 60172208 | 8mer-1a | 60172201 | 60172223 | 163 | -16.75 |
CAediting_688080 | chr9_63819626_+ | ENSG00000110077.13 | ENST00000420732 | hsa-miR-4477b | 60172201 | 60172208 | 8mer-1a | 60172201 | 60172223 | 163 | -16.75 |
CAediting_688080 | chr9_63819626_+ | ENSG00000110077.13 | ENST00000533989 | hsa-miR-4477b | 60172201 | 60172208 | 8mer-1a | 60172201 | 60172223 | 163 | -16.75 |
CAediting_1229415 | chr17_67471547_+ | ENSG00000110077.13 | ENST00000528851 | hsa-miR-548aa | 60172475 | 60172482 | 8mer-1a | 60172475 | 60172499 | 153 | -10.7 |
CAediting_524911 | chr7_5495852_- | ENSG00000110077.13 | ENST00000528851 | hsa-miR-589-3p | 60172569 | 60172575 | 7mer-m8 | 60172568 | 60172590 | 155 | -12.81 |
CAediting_524911 | chr7_5495852_- | ENSG00000110077.13 | ENST00000412309 | hsa-miR-589-3p | 60172569 | 60172575 | 7mer-m8 | 60172568 | 60172590 | 155 | -12.81 |
CAediting_524911 | chr7_5495852_- | ENSG00000110077.13 | ENST00000426738 | hsa-miR-589-3p | 60172569 | 60172575 | 7mer-m8 | 60172568 | 60172590 | 155 | -12.81 |
CAediting_524911 | chr7_5495852_- | ENSG00000110077.13 | ENST00000527254 | hsa-miR-589-3p | 60175573 | 60175579 | 7mer-m8 | 60175572 | 60175596 | 145 | -19.17 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for MS4A6A |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for MS4A6A |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for MS4A6A |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for MS4A6A |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
KIRC | CAediting_816130 | chr11_60176104_- | 0.0059202874813632 | 6.48753e-05 | 235.355 |
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RelatedDrugs for MS4A6A |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for MS4A6A |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
MS4A6A | C0017661 | IGA Glomerulonephritis | 1 | CTD_human |
MS4A6A | C1135196 | Heart Failure, Diastolic | 1 | CTD_human |