![]() |
||||||
|
![]() | |
![]() | |
![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
![]() | |
![]() | |
![]() | The effects of the RNA editing to the stability of the RNA structures |
![]() | |
![]() | |
![]() | |
![]() | |
![]() |
Editing gene: LIN7B (CAeditome ID:64130) |
Gene summary for LIN7B |
![]() |
Gene information | Gene symbol | LIN7B | Gene ID | 64130 |
Gene name | lin-7 homolog B, crumbs cell polarity complex component | |
Synonyms | LIN-7B|MALS-2|MALS2|VELI2 | |
Cytomap | 19q13.33 | |
Type of gene | protein-coding | |
Description | protein lin-7 homolog BhLin7BhVeli2mammalian lin-seven protein 2veli-2vertebrate lin-7 homolog 2 | |
Modification date | 20210518 | |
UniProtAcc | Q9HAP6 | |
Context |
![]() |
Gene | GO ID | GO term | PubMed ID |
Top |
RNA A-to-I events for LIN7B |
![]() |
![]() |
![]() |
![]() |
CAediting_1375197(49115860, +), CAediting_1375198(49115887, +), CAediting_1375199(49115899, +), CAediting_1375200(49115916, +), CAediting_1375201(49117918, +), |
Top |
RNA editing positional annotations for LIN7B using Annovar |
![]() |
CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_1375201 | chr19_49117918_+ | nonsynonymous SNV | ENST00000221459.5 | c.A502G | p.K168E | D | B | N |
CAediting_1375201 | chr19_49117918_+ | nonsynonymous SNV | ENST00000391864.6 | c.A292G | p.K98E | D | B | N |
![]() |
CAeditome ID | Position | Variant type |
CAediting_1375197 | chr19_49115860_+ | exonic |
CAediting_1375198 | chr19_49115887_+ | exonic |
CAediting_1375199 | chr19_49115899_+ | exonic |
CAediting_1375200 | chr19_49115916_+ | exonic |
CAediting_1375201 | chr19_49117918_+ | exonic |
![]() |
CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_1375197 | chr19_49115860_+ | SINE | Alu | AluSz |
CAediting_1375198 | chr19_49115887_+ | SINE | Alu | AluSz |
CAediting_1375199 | chr19_49115899_+ | SINE | Alu | AluSz |
CAediting_1375200 | chr19_49115916_+ | SINE | Alu | AluSz |
Top |
RNA A-to-I editing events in the alternative splicing sites for LIN7B |
![]() |
AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
![]() |
![]() |
Top |
Differntial gene expression between RNA A-to-I edited versus non-edited samples for LIN7B |
![]() * The grey color means N/A. |
![]() |
![]() * Click on the image to enlarge it in a new window. |
Top |
Protein coding region RNA A-to-I editings for LIN7B |
![]() * Click on the image to enlarge it in a new window. |
Top |
The effects of the RNA editing to the miRNA binding sites for LIN7B |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1375201 | chr19_49117918_+ | ENSG00000104863.10 | ENST00000595200 | hsa-miR-6736-3p | 49117916 | 49117922 | 7mer-m8 | 49117903 | 49117923 | 149.00 | -21.47 |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1375201 | chr19_49117918_+ | ENSG00000104863.10 | ENST00000595200 | hsa-miR-412-3p | 49117913 | 49117919 | 7mer-m8 | 49117898 | 49117920 | 154 | -26.94 |
CAediting_1375201 | chr19_49117918_+ | ENSG00000104863.10 | ENST00000595200 | hsa-miR-6837-3p | 49117914 | 49117919 | 6mer | 49117897 | 49117920 | 146 | -24.03 |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_846604 | chr11_93733708_- | ENSG00000104863.10 | ENST00000595200 | hsa-miR-1304-3p | 49116285 | 49116291 | 7mer-m8 | 49116273 | 49116292 | 143 | -14.62 |
CAediting_1399425 | chr20_1392958_- | ENSG00000104863.10 | ENST00000595200 | hsa-miR-6869-5p | 49116319 | 49116326 | 8mer-1a | 49116305 | 49116326 | 146 | -19.28 |
CAediting_396018 | chr5_1062918_- | ENSG00000104863.10 | ENST00000595200 | hsa-miR-4635 | 49116432 | 49116438 | 7mer-m8 | 49116419 | 49116439 | 146 | -17.51 |
CAediting_580943 | chr7_100356700_+ | ENSG00000104863.10 | ENST00000595200 | hsa-miR-6840-3p | 49116391 | 49116397 | 7mer-m8 | 49116376 | 49116398 | 146 | -30.68 |
![]() |
CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
![]() |
Top |
The effects of the RNA editing to the stability of the RNA structures for LIN7B |
![]() * Click on the image to enlarge it in a new window. |
ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
![]() |
CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
Top |
Relation with ADAR for LIN7B |
![]() |
Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
Top |
Relation with cancer stages for LIN7B |
![]() |
Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
Top |
Relation with survival for LIN7B |
![]() |
Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
Top |
RelatedDrugs for LIN7B |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for LIN7B |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |