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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: SDHD (CAeditome ID:6392)

Gene summary for SDHD

check button Gene summary
Gene informationGene symbol

SDHD

Gene ID

6392

Gene namesuccinate dehydrogenase complex subunit D
SynonymsCBT1|CII-4|CWS3|MC2DN3|PGL|PGL1|QPs3|SDH4|cybS
Cytomap

11q23.1

Type of geneprotein-coding
Descriptionsuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrialsuccinate dehydrogenase complex subunit D integral membrane proteinsuccinate-ubiquinone oxidoreductase cytochrome b small subunitsuccinate-ubiquinone reductase membrane ancho
Modification date20210518
UniProtAcc

O14521

Context- 32472550(Identification of SDHD c.170-1G>T variant in pedigree affected with carotid body tumor)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
SDHD

GO:0006099

Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

9533030

SDHD

GO:0005743

Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

9533030


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RNA A-to-I events for SDHD

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000204370.7

check button RNA A-to-I editing events in Cancer.
CAediting_851521(112088468, +), CAediting_851522(112088478, +), CAediting_851523(112090799, +), CAediting_851524(112091814, +), CAediting_851525(112091891, +), CAediting_851526(112091905, +), CAediting_851527(112091908, +), CAediting_851528(112091909, +), CAediting_851529(112091911, +), CAediting_851530(112091914, +), CAediting_851531(112091915, +), CAediting_851532(112091917, +), CAediting_851533(112091920, +), CAediting_851534(112091921, +), CAediting_851535(112091947, +), CAediting_851536(112091976, +), CAediting_851537(112091977, +), CAediting_851538(112091989, +), CAediting_851539(112091993, +), CAediting_851540(112092017, +), CAediting_851541(112092018, +), CAediting_851542(112093099, +), CAediting_851543(112093147, +), CAediting_851544(112093166, +), CAediting_851545(112093167, +), CAediting_851546(112093196, +), CAediting_851547(112093294, +), CAediting_851548(112093326, +), CAediting_851549(112093327, +), CAediting_851550(112093328, +), CAediting_851551(112093356, +), CAediting_851552(112094066, +), CAediting_851553(112094277, +), CAediting_851554(112094310, +), CAediting_851555(112094313, +), CAediting_851556(112094319, +), CAediting_851557(112094380, +), CAediting_851558(112094470, +), CAediting_851559(112094472, +), CAediting_851560(112094534, +), CAediting_851561(112094548, +), CAediting_851562(112094572, +), CAediting_851563(112094580, +), CAediting_851564(112095959, +), CAediting_851565(112095983, +), CAediting_851566(112097231, +), CAediting_851567(112097358, +), CAediting_851568(112097391, +), CAediting_851569(112097421, +), CAediting_851570(112097434, +), CAediting_851571(112097436, +), CAediting_851572(112097454, +), CAediting_851573(112099067, +), CAediting_851574(112099819, +), CAediting_851575(112099930, +), CAediting_851576(112100208, +), CAediting_851577(112100236, +), CAediting_851578(112100237, +), CAediting_851579(112100317, +), CAediting_851580(112100394, +), CAediting_851581(112104190, +), CAediting_851582(112104198, +), CAediting_851583(112104208, +), CAediting_851584(112104868, +), CAediting_851585(112104875, +), CAediting_851586(112104921, +), CAediting_851587(112104922, +), CAediting_851588(112104977, +), CAediting_851589(112105018, +), CAediting_851590(112105019, +), CAediting_851591(112106117, +), CAediting_851592(112107004, +), CAediting_851593(112107045, +), CAediting_851594(112107050, +), CAediting_851595(112107087, +), CAediting_851596(112108669, +), CAediting_851597(112108701, +), CAediting_851598(112108706, +), CAediting_851599(112108707, +), CAediting_851600(112108763, +), CAediting_851601(112108795, +), CAediting_851602(112111702, +), CAediting_851603(112112243, +), CAediting_851604(112112270, +), CAediting_851605(112112404, +), CAediting_851606(112112405, +), CAediting_851607(112112418, +), CAediting_851608(112112441, +), CAediting_851609(112113130, +), CAediting_851610(112113193, +), CAediting_851611(112114177, +), CAediting_851612(112114199, +), CAediting_851613(112114201, +), CAediting_851614(112114205, +), CAediting_851615(112114263, +), CAediting_851616(112114264, +), CAediting_851617(112114267, +), CAediting_851618(112114271, +), CAediting_851619(112114277, +), CAediting_851620(112114904, +), CAediting_851621(112114949, +), CAediting_851622(112114981, +), CAediting_851623(112115001, +), CAediting_851624(112115020, +), CAediting_851625(112115047, +), CAediting_851626(112115055, +), CAediting_851627(112115060, +), CAediting_851628(112118053, +), CAediting_851629(112118062, +), CAediting_851630(112118086, +), CAediting_851631(112118087, +), CAediting_851632(112118126, +), CAediting_851633(112118127, +), CAediting_851634(112118147, +), CAediting_851635(112118187, +), CAediting_851636(112118193, +), CAediting_851637(112118210, +), CAediting_851638(112118211, +), CAediting_851639(112118245, +), CAediting_851640(112118247, +), CAediting_851641(112119171, +), CAediting_851642(112119201, +), CAediting_851643(112119202, +), CAediting_851644(112119227, +), CAediting_851645(112119231, +), CAediting_851646(112119232, +), CAediting_851647(112119304, +), CAediting_851648(112119341, +), CAediting_851649(112119346, +), CAediting_851650(112119350, +), CAediting_851651(112119359, +), CAediting_851652(112119367, +), CAediting_851653(112119368, +), CAediting_851654(112119369, +), CAediting_851655(112119381, +), CAediting_851656(112119383, +), CAediting_851657(112119384, +), CAediting_851658(112119390, +), CAediting_851659(112119683, +), CAediting_851660(112119684, +), CAediting_851661(112119705, +), CAediting_851662(112119706, +), CAediting_851663(112119724, +), CAediting_851664(112119729, +), CAediting_851665(112119752, +), CAediting_851666(112119755, +), CAediting_851667(112119767, +), CAediting_851668(112119768, +), CAediting_851669(112119769, +), CAediting_851670(112119780, +), CAediting_851671(112119783, +), CAediting_851672(112119784, +), CAediting_851673(112119785, +), CAediting_851674(112119786, +), CAediting_851675(112119787, +), CAediting_851676(112119789, +), CAediting_851677(112119792, +), CAediting_851678(112119793, +), CAediting_851679(112119794, +), CAediting_851680(112119795, +), CAediting_851681(112119808, +), CAediting_851682(112119816, +), CAediting_851683(112119824, +), CAediting_851684(112119830, +), CAediting_851685(112119834, +), CAediting_851686(112119841, +), CAediting_851687(112119851, +), CAediting_851688(112119857, +), CAediting_851689(112119865, +), CAediting_851690(112119887, +),

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RNA editing positional annotations for SDHD using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_851544chr11_112093166_+nonsynonymous SNVENST00000526592.4c.A401Gp.Q134RD.N

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_851521chr11_112088468_+ncRNA_intronic
CAediting_851522chr11_112088478_+ncRNA_intronic
CAediting_851523chr11_112090799_+ncRNA_intronic
CAediting_851524chr11_112091814_+ncRNA_intronic
CAediting_851525chr11_112091891_+ncRNA_intronic
CAediting_851526chr11_112091905_+ncRNA_intronic
CAediting_851527chr11_112091908_+ncRNA_intronic
CAediting_851528chr11_112091909_+ncRNA_intronic
CAediting_851529chr11_112091911_+ncRNA_intronic
CAediting_851530chr11_112091914_+ncRNA_intronic
CAediting_851531chr11_112091915_+ncRNA_intronic
CAediting_851532chr11_112091917_+ncRNA_intronic
CAediting_851533chr11_112091920_+ncRNA_intronic
CAediting_851534chr11_112091921_+ncRNA_intronic
CAediting_851535chr11_112091947_+ncRNA_intronic
CAediting_851536chr11_112091976_+ncRNA_intronic
CAediting_851537chr11_112091977_+ncRNA_intronic
CAediting_851538chr11_112091989_+ncRNA_intronic
CAediting_851539chr11_112091993_+ncRNA_intronic
CAediting_851540chr11_112092017_+ncRNA_intronic
CAediting_851541chr11_112092018_+ncRNA_intronic
CAediting_851542chr11_112093099_+exonic
CAediting_851543chr11_112093147_+exonic
CAediting_851544chr11_112093166_+exonic
CAediting_851545chr11_112093167_+exonic
CAediting_851546chr11_112093196_+exonic
CAediting_851547chr11_112093294_+ncRNA_intronic
CAediting_851548chr11_112093326_+ncRNA_intronic
CAediting_851549chr11_112093327_+ncRNA_intronic
CAediting_851550chr11_112093328_+ncRNA_intronic
CAediting_851551chr11_112093356_+ncRNA_intronic
CAediting_851552chr11_112094066_+ncRNA_intronic
CAediting_851553chr11_112094277_+ncRNA_intronic
CAediting_851554chr11_112094310_+ncRNA_intronic
CAediting_851555chr11_112094313_+ncRNA_intronic
CAediting_851556chr11_112094319_+ncRNA_intronic
CAediting_851557chr11_112094380_+ncRNA_intronic
CAediting_851558chr11_112094470_+ncRNA_intronic
CAediting_851559chr11_112094472_+ncRNA_intronic
CAediting_851560chr11_112094534_+ncRNA_intronic
CAediting_851561chr11_112094548_+ncRNA_intronic
CAediting_851562chr11_112094572_+ncRNA_intronic
CAediting_851563chr11_112094580_+ncRNA_intronic
CAediting_851564chr11_112095959_+ncRNA_intronic
CAediting_851565chr11_112095983_+ncRNA_intronic
CAediting_851566chr11_112097231_+ncRNA_intronic
CAediting_851567chr11_112097358_+ncRNA_intronic
CAediting_851568chr11_112097391_+ncRNA_intronic
CAediting_851569chr11_112097421_+ncRNA_intronic
CAediting_851570chr11_112097434_+ncRNA_intronic
CAediting_851571chr11_112097436_+ncRNA_intronic
CAediting_851572chr11_112097454_+ncRNA_intronic
CAediting_851573chr11_112099067_+ncRNA_intronic
CAediting_851574chr11_112099819_+ncRNA_intronic
CAediting_851575chr11_112099930_+ncRNA_intronic
CAediting_851576chr11_112100208_+ncRNA_intronic
CAediting_851577chr11_112100236_+ncRNA_intronic
CAediting_851578chr11_112100237_+ncRNA_intronic
CAediting_851579chr11_112100317_+ncRNA_intronic
CAediting_851580chr11_112100394_+ncRNA_intronic
CAediting_851581chr11_112104190_+ncRNA_intronic
CAediting_851582chr11_112104198_+ncRNA_intronic
CAediting_851583chr11_112104208_+ncRNA_intronic
CAediting_851584chr11_112104868_+ncRNA_intronic
CAediting_851585chr11_112104875_+ncRNA_intronic
CAediting_851586chr11_112104921_+ncRNA_intronic
CAediting_851587chr11_112104922_+ncRNA_intronic
CAediting_851588chr11_112104977_+ncRNA_intronic
CAediting_851589chr11_112105018_+ncRNA_intronic
CAediting_851590chr11_112105019_+ncRNA_intronic
CAediting_851591chr11_112106117_+ncRNA_intronic
CAediting_851592chr11_112107004_+ncRNA_intronic
CAediting_851593chr11_112107045_+ncRNA_intronic
CAediting_851594chr11_112107050_+ncRNA_intronic
CAediting_851595chr11_112107087_+ncRNA_intronic
CAediting_851596chr11_112108669_+ncRNA_intronic
CAediting_851597chr11_112108701_+ncRNA_intronic
CAediting_851598chr11_112108706_+ncRNA_intronic
CAediting_851599chr11_112108707_+ncRNA_intronic
CAediting_851600chr11_112108763_+ncRNA_intronic
CAediting_851601chr11_112108795_+ncRNA_intronic
CAediting_851602chr11_112111702_+ncRNA_intronic
CAediting_851603chr11_112112243_+ncRNA_intronic
CAediting_851604chr11_112112270_+ncRNA_intronic
CAediting_851605chr11_112112404_+ncRNA_intronic
CAediting_851606chr11_112112405_+ncRNA_intronic
CAediting_851607chr11_112112418_+ncRNA_intronic
CAediting_851608chr11_112112441_+ncRNA_intronic
CAediting_851609chr11_112113130_+ncRNA_intronic
CAediting_851610chr11_112113193_+ncRNA_intronic
CAediting_851611chr11_112114177_+ncRNA_intronic
CAediting_851612chr11_112114199_+ncRNA_intronic
CAediting_851613chr11_112114201_+ncRNA_intronic
CAediting_851614chr11_112114205_+ncRNA_intronic
CAediting_851615chr11_112114263_+ncRNA_intronic
CAediting_851616chr11_112114264_+ncRNA_intronic
CAediting_851617chr11_112114267_+ncRNA_intronic
CAediting_851618chr11_112114271_+ncRNA_intronic
CAediting_851619chr11_112114277_+ncRNA_intronic
CAediting_851620chr11_112114904_+ncRNA_intronic
CAediting_851621chr11_112114949_+ncRNA_intronic
CAediting_851622chr11_112114981_+ncRNA_intronic
CAediting_851623chr11_112115001_+ncRNA_intronic
CAediting_851624chr11_112115020_+ncRNA_intronic
CAediting_851625chr11_112115047_+ncRNA_intronic
CAediting_851626chr11_112115055_+ncRNA_intronic
CAediting_851627chr11_112115060_+ncRNA_intronic
CAediting_851628chr11_112118053_+ncRNA_intronic
CAediting_851629chr11_112118062_+ncRNA_intronic
CAediting_851630chr11_112118086_+ncRNA_intronic
CAediting_851631chr11_112118087_+ncRNA_intronic
CAediting_851632chr11_112118126_+ncRNA_intronic
CAediting_851633chr11_112118127_+ncRNA_intronic
CAediting_851634chr11_112118147_+ncRNA_intronic
CAediting_851635chr11_112118187_+ncRNA_intronic
CAediting_851636chr11_112118193_+ncRNA_intronic
CAediting_851637chr11_112118210_+ncRNA_intronic
CAediting_851638chr11_112118211_+ncRNA_intronic
CAediting_851639chr11_112118245_+ncRNA_intronic
CAediting_851640chr11_112118247_+ncRNA_intronic
CAediting_851641chr11_112119171_+ncRNA_intronic
CAediting_851642chr11_112119201_+ncRNA_intronic
CAediting_851643chr11_112119202_+ncRNA_intronic
CAediting_851644chr11_112119227_+ncRNA_intronic
CAediting_851645chr11_112119231_+ncRNA_intronic
CAediting_851646chr11_112119232_+ncRNA_intronic
CAediting_851647chr11_112119304_+ncRNA_intronic
CAediting_851648chr11_112119341_+ncRNA_intronic
CAediting_851649chr11_112119346_+ncRNA_intronic
CAediting_851650chr11_112119350_+ncRNA_intronic
CAediting_851651chr11_112119359_+ncRNA_intronic
CAediting_851652chr11_112119367_+ncRNA_intronic
CAediting_851653chr11_112119368_+ncRNA_intronic
CAediting_851654chr11_112119369_+ncRNA_intronic
CAediting_851655chr11_112119381_+ncRNA_intronic
CAediting_851656chr11_112119383_+ncRNA_intronic
CAediting_851657chr11_112119384_+ncRNA_intronic
CAediting_851658chr11_112119390_+ncRNA_intronic
CAediting_851659chr11_112119683_+ncRNA_intronic
CAediting_851660chr11_112119684_+ncRNA_intronic
CAediting_851661chr11_112119705_+ncRNA_intronic
CAediting_851662chr11_112119706_+ncRNA_intronic
CAediting_851663chr11_112119724_+ncRNA_intronic
CAediting_851664chr11_112119729_+ncRNA_intronic
CAediting_851665chr11_112119752_+ncRNA_intronic
CAediting_851666chr11_112119755_+ncRNA_intronic
CAediting_851667chr11_112119767_+ncRNA_intronic
CAediting_851668chr11_112119768_+ncRNA_intronic
CAediting_851669chr11_112119769_+ncRNA_intronic
CAediting_851670chr11_112119780_+ncRNA_intronic
CAediting_851671chr11_112119783_+ncRNA_intronic
CAediting_851672chr11_112119784_+ncRNA_intronic
CAediting_851673chr11_112119785_+ncRNA_intronic
CAediting_851674chr11_112119786_+ncRNA_intronic
CAediting_851675chr11_112119787_+ncRNA_intronic
CAediting_851676chr11_112119789_+ncRNA_intronic
CAediting_851677chr11_112119792_+ncRNA_intronic
CAediting_851678chr11_112119793_+ncRNA_intronic
CAediting_851679chr11_112119794_+ncRNA_intronic
CAediting_851680chr11_112119795_+ncRNA_intronic
CAediting_851681chr11_112119808_+ncRNA_intronic
CAediting_851682chr11_112119816_+ncRNA_intronic
CAediting_851683chr11_112119824_+ncRNA_intronic
CAediting_851684chr11_112119830_+ncRNA_intronic
CAediting_851685chr11_112119834_+ncRNA_intronic
CAediting_851686chr11_112119841_+ncRNA_intronic
CAediting_851687chr11_112119851_+ncRNA_intronic
CAediting_851688chr11_112119857_+ncRNA_intronic
CAediting_851689chr11_112119865_+ncRNA_intronic
CAediting_851690chr11_112119887_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_851521chr11_112088468_+SINEAluAluSx1
CAediting_851522chr11_112088478_+SINEAluAluSx1
CAediting_851523chr11_112090799_+SINEAluAluSz
CAediting_851524chr11_112091814_+SINEAluAluSx4
CAediting_851525chr11_112091891_+SINEAluAluSx4
CAediting_851526chr11_112091905_+SINEAluAluSx4
CAediting_851527chr11_112091908_+SINEAluAluSx4
CAediting_851528chr11_112091909_+SINEAluAluSx4
CAediting_851529chr11_112091911_+SINEAluAluSx4
CAediting_851530chr11_112091914_+SINEAluAluSx4
CAediting_851531chr11_112091915_+SINEAluAluSx4
CAediting_851532chr11_112091917_+SINEAluAluSx4
CAediting_851533chr11_112091920_+SINEAluAluSx4
CAediting_851534chr11_112091921_+SINEAluAluSx4
CAediting_851535chr11_112091947_+SINEAluAluSx4
CAediting_851536chr11_112091976_+SINEAluAluSx4
CAediting_851537chr11_112091977_+SINEAluAluSx4
CAediting_851538chr11_112091989_+SINEAluAluSx4
CAediting_851539chr11_112091993_+SINEAluAluSx4
CAediting_851540chr11_112092017_+SINEAluAluSx4
CAediting_851541chr11_112092018_+SINEAluAluSx4
CAediting_851542chr11_112093099_+SINEAluAluSp
CAediting_851543chr11_112093147_+SINEAluAluSp
CAediting_851544chr11_112093166_+SINEAluAluSp
CAediting_851545chr11_112093167_+SINEAluAluSp
CAediting_851546chr11_112093196_+SINEAluAluSp
CAediting_851547chr11_112093294_+SINEAluAluSp
CAediting_851548chr11_112093326_+SINEAluAluSp
CAediting_851549chr11_112093327_+SINEAluAluSp
CAediting_851550chr11_112093328_+SINEAluAluSp
CAediting_851551chr11_112093356_+SINEAluAluSp
CAediting_851552chr11_112094066_+SINEAluAluJr
CAediting_851553chr11_112094277_+SINEAluAluSx4
CAediting_851554chr11_112094310_+SINEAluAluSx4
CAediting_851555chr11_112094313_+SINEAluAluSx4
CAediting_851556chr11_112094319_+SINEAluAluSx4
CAediting_851557chr11_112094380_+SINEAluAluSx4
CAediting_851558chr11_112094470_+SINEAluAluJr
CAediting_851559chr11_112094472_+SINEAluAluJr
CAediting_851560chr11_112094534_+SINEAluAluJr
CAediting_851561chr11_112094548_+SINEAluAluJr
CAediting_851562chr11_112094572_+SINEAluAluJr
CAediting_851563chr11_112094580_+SINEAluAluJr
CAediting_851564chr11_112095959_+SINEAluAluY
CAediting_851565chr11_112095983_+SINEAluAluY
CAediting_851566chr11_112097231_+SINEAluAluJr4
CAediting_851567chr11_112097358_+SINEAluAluJr4
CAediting_851568chr11_112097391_+SINEAluAluJr4
CAediting_851569chr11_112097421_+SINEAluAluJr4
CAediting_851570chr11_112097434_+SINEAluAluJr4
CAediting_851571chr11_112097436_+SINEAluAluJr4
CAediting_851572chr11_112097454_+SINEAluAluJr4
CAediting_851573chr11_112099067_+SINEAluAluSq2
CAediting_851574chr11_112099819_+SINEAluAluJo
CAediting_851575chr11_112099930_+SINEAluAluJo
CAediting_851576chr11_112100208_+SINEAluAluSp
CAediting_851577chr11_112100236_+SINEAluAluSp
CAediting_851578chr11_112100237_+SINEAluAluSp
CAediting_851579chr11_112100317_+SINEAluAluSp
CAediting_851580chr11_112100394_+SINEAluAluSp
CAediting_851581chr11_112104190_+SINEAluAluSq2
CAediting_851582chr11_112104198_+SINEAluAluSq2
CAediting_851583chr11_112104208_+SINEAluAluSq2
CAediting_851584chr11_112104868_+SINEAluAluSx4
CAediting_851585chr11_112104875_+SINEAluAluSx4
CAediting_851586chr11_112104921_+SINEAluAluSx4
CAediting_851587chr11_112104922_+SINEAluAluSx4
CAediting_851588chr11_112104977_+SINEAluAluSx4
CAediting_851589chr11_112105018_+SINEAluAluSx4
CAediting_851590chr11_112105019_+SINEAluAluSx4
CAediting_851591chr11_112106117_+SINEAluAluSp
CAediting_851592chr11_112107004_+SINEAluAluJr
CAediting_851593chr11_112107045_+SINEAluAluJr
CAediting_851594chr11_112107050_+SINEAluAluJr
CAediting_851595chr11_112107087_+SINEAluAluJr
CAediting_851596chr11_112108669_+SINEAluAluSc
CAediting_851597chr11_112108701_+SINEAluAluSc
CAediting_851598chr11_112108706_+SINEAluAluSc
CAediting_851599chr11_112108707_+SINEAluAluSc
CAediting_851600chr11_112108763_+SINEAluAluSc
CAediting_851601chr11_112108795_+SINEAluAluSc
CAediting_851602chr11_112111702_+SINEAluAluSx
CAediting_851603chr11_112112243_+SINEAluAluJr4
CAediting_851604chr11_112112270_+SINEAluAluJr4
CAediting_851605chr11_112112404_+SINEAluAluJr4
CAediting_851606chr11_112112405_+SINEAluAluJr4
CAediting_851607chr11_112112418_+SINEAluAluJr4
CAediting_851608chr11_112112441_+SINEAluAluJr4
CAediting_851609chr11_112113130_+SINEAluAluSc
CAediting_851610chr11_112113193_+SINEAluAluSc
CAediting_851611chr11_112114177_+SINEAluAluJr4
CAediting_851612chr11_112114199_+SINEAluAluJr4
CAediting_851613chr11_112114201_+SINEAluAluJr4
CAediting_851614chr11_112114205_+SINEAluAluJr4
CAediting_851615chr11_112114263_+SINEAluAluJr4
CAediting_851616chr11_112114264_+SINEAluAluJr4
CAediting_851617chr11_112114267_+SINEAluAluJr4
CAediting_851618chr11_112114271_+SINEAluAluJr4
CAediting_851619chr11_112114277_+SINEAluAluJr4
CAediting_851620chr11_112114904_+SINEAluAluSx1
CAediting_851621chr11_112114949_+SINEAluAluSx1
CAediting_851622chr11_112114981_+SINEAluAluSx1
CAediting_851623chr11_112115001_+SINEAluAluSx1
CAediting_851624chr11_112115020_+SINEAluAluSx1
CAediting_851625chr11_112115047_+SINEAluAluSx1
CAediting_851626chr11_112115055_+SINEAluAluSx1
CAediting_851627chr11_112115060_+SINEAluAluSx1
CAediting_851628chr11_112118053_+SINEAluAluSx1
CAediting_851629chr11_112118062_+SINEAluAluSx1
CAediting_851630chr11_112118086_+SINEAluAluSx1
CAediting_851631chr11_112118087_+SINEAluAluSx1
CAediting_851632chr11_112118126_+SINEAluAluSx1
CAediting_851633chr11_112118127_+SINEAluAluSx1
CAediting_851634chr11_112118147_+SINEAluAluSx1
CAediting_851635chr11_112118187_+SINEAluAluSx1
CAediting_851636chr11_112118193_+SINEAluAluSx1
CAediting_851637chr11_112118210_+SINEAluAluSx1
CAediting_851638chr11_112118211_+SINEAluAluSx1
CAediting_851639chr11_112118245_+SINEAluAluSx1
CAediting_851640chr11_112118247_+SINEAluAluSx1
CAediting_851641chr11_112119171_+SINEAluAluJb
CAediting_851642chr11_112119201_+SINEAluAluJb
CAediting_851643chr11_112119202_+SINEAluAluJb
CAediting_851644chr11_112119227_+SINEAluAluJb
CAediting_851645chr11_112119231_+SINEAluAluJb
CAediting_851646chr11_112119232_+SINEAluAluJb
CAediting_851647chr11_112119304_+SINEAluAluJb
CAediting_851648chr11_112119341_+SINEAluAluJb
CAediting_851649chr11_112119346_+SINEAluAluJb
CAediting_851650chr11_112119350_+SINEAluAluJb
CAediting_851651chr11_112119359_+SINEAluAluJb
CAediting_851652chr11_112119367_+SINEAluAluJb
CAediting_851653chr11_112119368_+SINEAluAluJb
CAediting_851654chr11_112119369_+SINEAluAluJb
CAediting_851655chr11_112119381_+SINEAluAluJb
CAediting_851656chr11_112119383_+SINEAluAluJb
CAediting_851657chr11_112119384_+SINEAluAluJb
CAediting_851658chr11_112119390_+SINEAluAluJb
CAediting_851659chr11_112119683_+SINEAluAluSz
CAediting_851660chr11_112119684_+SINEAluAluSz
CAediting_851661chr11_112119705_+SINEAluAluSz
CAediting_851662chr11_112119706_+SINEAluAluSz
CAediting_851663chr11_112119724_+SINEAluAluSz
CAediting_851664chr11_112119729_+SINEAluAluSz
CAediting_851665chr11_112119752_+SINEAluAluSz
CAediting_851666chr11_112119755_+SINEAluAluSz
CAediting_851667chr11_112119767_+SINEAluAluSz
CAediting_851668chr11_112119768_+SINEAluAluSz
CAediting_851669chr11_112119769_+SINEAluAluSz
CAediting_851670chr11_112119780_+SINEAluAluSz
CAediting_851671chr11_112119783_+SINEAluAluSz
CAediting_851672chr11_112119784_+SINEAluAluSz
CAediting_851673chr11_112119785_+SINEAluAluSz
CAediting_851674chr11_112119786_+SINEAluAluSz
CAediting_851675chr11_112119787_+SINEAluAluSz
CAediting_851676chr11_112119789_+SINEAluAluSz
CAediting_851677chr11_112119792_+SINEAluAluSz
CAediting_851678chr11_112119793_+SINEAluAluSz
CAediting_851679chr11_112119794_+SINEAluAluSz
CAediting_851680chr11_112119795_+SINEAluAluSz
CAediting_851681chr11_112119808_+SINEAluAluSz
CAediting_851682chr11_112119816_+SINEAluAluSz
CAediting_851683chr11_112119824_+SINEAluAluSz
CAediting_851684chr11_112119830_+SINEAluAluSz
CAediting_851685chr11_112119834_+SINEAluAluSz
CAediting_851686chr11_112119841_+SINEAluAluSz
CAediting_851687chr11_112119851_+SINEAluAluSz
CAediting_851688chr11_112119857_+SINEAluAluSz
CAediting_851689chr11_112119865_+SINEAluAluSz
CAediting_851690chr11_112119887_+SINEAluAluSz

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RNA A-to-I editing events in the alternative splicing sites for SDHD

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000204370.7.SDHD.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000204370.7.SDHD.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SDHD

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for SDHD

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for SDHD

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_851654chr11_112119369_+ENSG00000204370.7ENST00000534010hsa-miR-3189-3p1121193631121193697mer-m8112119347112119370153.00-26.36
CAediting_851654chr11_112119369_+ENSG00000204370.7ENST00000534010hsa-miR-6813-3p1121193641121193707mer-m8112119351112119371140.00-11.59
CAediting_851655chr11_112119381_+ENSG00000204370.7ENST00000534010hsa-miR-106a-3p1121193771121193837mer-1a112119362112119383141.00-16.54
CAediting_851655chr11_112119381_+ENSG00000204370.7ENST00000534010hsa-miR-43271121193791121193857mer-m8112119368112119386140.00-16.40
CAediting_851649chr11_112119346_+ENSG00000204370.7ENST00000534010hsa-miR-1255b-2-3p1121193401121193467mer-m8112119326112119347140.00-14.47
CAediting_851649chr11_112119346_+ENSG00000204370.7ENST00000534010hsa-miR-4776-5p1121193431121193497mer-m8112119328112119350147.00-24.15
CAediting_851649chr11_112119346_+ENSG00000204370.7ENST00000534010hsa-miR-4776-5p1121193431121193497mer-m8112119328112119350147.00-24.15
CAediting_851649chr11_112119346_+ENSG00000204370.7ENST00000534010hsa-miR-4800-5p1121193441121193507mer-m8112119331112119351147.00-21.97
CAediting_851650chr11_112119350_+ENSG00000204370.7ENST00000534010hsa-miR-39371121193471121193537mer-m8112119332112119354142.00-18.04
CAediting_851652chr11_112119367_+ENSG00000204370.7ENST00000534010hsa-miR-6771-5p1121193611121193688mer-1a112119349112119368160.00-30.26
CAediting_851653chr11_112119368_+ENSG00000204370.7ENST00000534010hsa-miR-3261121193631121193697mer-m8112119351112119370140.00-13.96
CAediting_851653chr11_112119368_+ENSG00000204370.7ENST00000534010hsa-miR-330-5p1121193631121193697mer-m8112119347112119370143.00-22.58
CAediting_851653chr11_112119368_+ENSG00000204370.7ENST00000534010hsa-miR-43141121193621121193687mer-m8112119351112119369143.00-24.03
CAediting_851653chr11_112119368_+ENSG00000204370.7ENST00000534010hsa-miR-514a-5p1121193641121193707mer-m8112119348112119371150.00-18.62
CAediting_851653chr11_112119368_+ENSG00000204370.7ENST00000534010hsa-miR-514a-5p1121193641121193707mer-m8112119348112119371150.00-18.62
CAediting_851653chr11_112119368_+ENSG00000204370.7ENST00000534010hsa-miR-514a-5p1121193641121193707mer-m8112119348112119371150.00-18.62
CAediting_851657chr11_112119384_+ENSG00000204370.7ENST00000534010hsa-miR-4650-5p1121193821121193898mer-1a112119369112119389148.00-17.18
CAediting_851657chr11_112119384_+ENSG00000204370.7ENST00000534010hsa-miR-4650-5p1121193821121193898mer-1a112119369112119389148.00-17.18
CAediting_851657chr11_112119384_+ENSG00000204370.7ENST00000534010hsa-miR-6735-3p1121193801121193867mer-m8112119366112119387150.00-25.39
CAediting_851658chr11_112119390_+ENSG00000204370.7ENST00000534010hsa-miR-663b1121193881121193947mer-m8112119374112119395155.00-26.90

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_851650chr11_112119350_+ENSG00000204370.7ENST00000534010hsa-miR-121141121193461121193527mer-m8112119334112119353143-21.87
CAediting_851658chr11_112119390_+ENSG00000204370.7ENST00000534010hsa-miR-24-3p1121193861121193938mer-1a112119372112119393140-17.01
CAediting_851658chr11_112119390_+ENSG00000204370.7ENST00000534010hsa-miR-24-3p1121193861121193938mer-1a112119372112119393140-17.01
CAediting_851652chr11_112119367_+ENSG00000204370.7ENST00000534010hsa-miR-30b-3p1121193601121193678mer-1a112119346112119367151-18.54
CAediting_851650chr11_112119350_+ENSG00000204370.7ENST00000534010hsa-miR-31651121193451121193517mer-m8112119333112119352148-19.34
CAediting_851650chr11_112119350_+ENSG00000204370.7ENST00000534010hsa-miR-36651121193481121193547mer-m8112119338112119355140-16.03
CAediting_851652chr11_112119367_+ENSG00000204370.7ENST00000534010hsa-miR-3689a-3p1121193601121193678mer-1a112119346112119367149-22.05
CAediting_851652chr11_112119367_+ENSG00000204370.7ENST00000534010hsa-miR-3689b-3p1121193601121193678mer-1a112119346112119367149-22.1
CAediting_851652chr11_112119367_+ENSG00000204370.7ENST00000534010hsa-miR-3689c1121193601121193678mer-1a112119346112119367149-22.1
CAediting_851658chr11_112119390_+ENSG00000204370.7ENST00000534010hsa-miR-3934-3p1121193851121193917mer-m8112119370112119392151-19.16
CAediting_851651chr11_112119359_+ENSG00000204370.7ENST00000534010hsa-miR-44781121193561121193627mer-m8112119348112119363149-22.24
CAediting_851651chr11_112119359_+ENSG00000204370.7ENST00000534010hsa-miR-4649-3p1121193531121193597mer-m8112119340112119360140-14.63
CAediting_851651chr11_112119359_+ENSG00000204370.7ENST00000534010hsa-miR-485-5p1121193571121193637mer-m8112119343112119364149-16.01
CAediting_851652chr11_112119367_+ENSG00000204370.7ENST00000534010hsa-miR-6779-5p1121193601121193678mer-1a112119349112119367148-23.1
CAediting_851651chr11_112119359_+ENSG00000204370.7ENST00000534010hsa-miR-7160-5p1121193541121193607mer-m8112119344112119361144-18.41
CAediting_851652chr11_112119367_+ENSG00000204370.7ENST00000534010hsa-miR-887-5p1121193611121193688mer-1a112119349112119368143-15.14
CAediting_851653chr11_112119368_+ENSG00000204370.7ENST00000534010hsa-miR-887-5p1121193611121193688mer-1a112119349112119368143-15.14

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_573001chr7_92204086_-ENSG00000204370.7ENST00000528182hsa-miR-1285-5p1120951601120951667mer-m8112095147112095167140-12.28
CAediting_573001chr7_92204086_-ENSG00000204370.7ENST00000528048hsa-miR-1285-5p1120951601120951667mer-m8112095147112095167140-12.28
CAediting_573001chr7_92204086_-ENSG00000204370.7ENST00000375549hsa-miR-1285-5p1120951601120951667mer-m8112095147112095167140-12.28
CAediting_573001chr7_92204086_-ENSG00000204370.7ENST00000526592hsa-miR-1285-5p1120951601120951667mer-m8112095147112095167140-12.28
CAediting_573001chr7_92204086_-ENSG00000204370.7ENST00000525291hsa-miR-1285-5p1120951601120951667mer-m8112095147112095167140-12.28
CAediting_1399425chr20_1392958_-ENSG00000204370.7ENST00000534010hsa-miR-6869-5p1121193221121193287mer-1a112119305112119328155-32.79

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SDHD

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for SDHD

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
OVCAediting_851657chr11_112119384_+0.0461877768380090.254194223408244....

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Relation with cancer stages for SDHD

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for SDHD

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for SDHD

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
SDHDO14521DB00756HexachloropheneSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial SmallMoleculeDrugapproved|withdrawn

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RelatedDiseases for SDHD

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
SDHDC1708353Hereditary Paraganglioma-Pheochromocytoma Syndrome9CLINGEN;GENOMICS_ENGLAND
SDHDC0030421Paraganglioma6CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT
SDHDC0031511Pheochromocytoma3CGI;CTD_human;GENOMICS_ENGLAND;UNIPROT
SDHDC1855008Mitochondrial Complex II Deficiency3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
SDHDC0024586Malignant Carcinoid Syndrome1ORPHANET
SDHDC0025202melanoma1CTD_human
SDHDC0751651Mitochondrial Diseases1GENOMICS_ENGLAND
SDHDC1847319PARAGANGLIOMA AND GASTRIC STROMAL SARCOMA1CTD_human;GENOMICS_ENGLAND;ORPHANET