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Editing gene: RPL28 (CAeditome ID:6158)

Gene summary for RPL28

Gene summary

Gene information	Gene symbol	RPL28
	Gene ID	6158
	Gene name	ribosomal protein L28
	Synonyms	L28
	Cytomap	19q13.42
	Type of gene	protein-coding
	Description	60S ribosomal protein L28large ribosomal subunit protein eL28
	Modification date	20210518
	UniProtAcc	P46779
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
RPL28	GO:0003735	60S ribosomal protein L28	23636399
RPL28	GO:0030425	60S ribosomal protein L28	15121898
RPL28	GO:0036464	60S ribosomal protein L28	15121898
RPL28	GO:0044297	60S ribosomal protein L28	15121898
RPL28	GO:0022626	60S ribosomal protein L28	23636399

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RNA A-to-I events for RPL28

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000108107.11

RNA A-to-I editing events in Cancer.

CAediting_1391344(55389141, +), CAediting_1391345(55389146, +), CAediting_1391346(55389149, +), CAediting_1391347(55389155, +), CAediting_1391348(55389165, +), CAediting_1391349(55389174, +), CAediting_1391350(55389175, +), CAediting_1391351(55389198, +), CAediting_1391352(55389220, +), CAediting_1391353(55389243, +), CAediting_1391354(55389262, +), CAediting_1391355(55389275, +), CAediting_1391356(55389280, +), CAediting_1391357(55389284, +), CAediting_1391358(55389285, +), CAediting_1391359(55389287, +), CAediting_1391360(55389290, +), CAediting_1391361(55389300, +), CAediting_1391362(55389318, +), CAediting_1391363(55389324, +), CAediting_1391364(55389331, +), CAediting_1391365(55390228, +), CAediting_1391366(55390261, +), CAediting_1391367(55390269, +), CAediting_1391368(55390284, +), CAediting_1391369(55390291, +), CAediting_1391370(55390305, +), CAediting_1391371(55390322, +), CAediting_1391372(55390331, +), CAediting_1391373(55390334, +), CAediting_1391374(55390341, +), CAediting_1391375(55390346, +), CAediting_1391376(55390360, +), CAediting_1391377(55390388, +), CAediting_1391378(55390414, +), CAediting_1391379(55390440, +), CAediting_1391380(55390441, +), CAediting_1391381(55390444, +), CAediting_1391382(55390448, +), CAediting_1391383(55390467, +), CAediting_1391384(55390521, +), CAediting_1391385(55391478, +), CAediting_1391386(55392510, +), CAediting_1391387(55392736, +), CAediting_1391388(55396012, +), CAediting_1391389(55396137, +), CAediting_1391390(55396144, +), CAediting_1391391(55396150, +), CAediting_1391392(55396186, +), CAediting_1391393(55397080, +), CAediting_1391394(55398075, +),

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RNA editing positional annotations for RPL28 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1391344	chr19_55389141_+	ncRNA_exonic
CAediting_1391345	chr19_55389146_+	ncRNA_exonic
CAediting_1391346	chr19_55389149_+	ncRNA_exonic
CAediting_1391347	chr19_55389155_+	ncRNA_exonic
CAediting_1391348	chr19_55389165_+	ncRNA_exonic
CAediting_1391349	chr19_55389174_+	ncRNA_exonic
CAediting_1391350	chr19_55389175_+	ncRNA_exonic
CAediting_1391351	chr19_55389198_+	ncRNA_exonic
CAediting_1391352	chr19_55389220_+	ncRNA_exonic
CAediting_1391353	chr19_55389243_+	ncRNA_exonic
CAediting_1391354	chr19_55389262_+	ncRNA_exonic
CAediting_1391355	chr19_55389275_+	ncRNA_exonic
CAediting_1391356	chr19_55389280_+	ncRNA_exonic
CAediting_1391357	chr19_55389284_+	ncRNA_exonic
CAediting_1391358	chr19_55389285_+	ncRNA_exonic
CAediting_1391359	chr19_55389287_+	ncRNA_exonic
CAediting_1391360	chr19_55389290_+	ncRNA_exonic
CAediting_1391361	chr19_55389300_+	ncRNA_exonic
CAediting_1391362	chr19_55389318_+	ncRNA_exonic
CAediting_1391363	chr19_55389324_+	ncRNA_exonic
CAediting_1391364	chr19_55389331_+	ncRNA_exonic
CAediting_1391365	chr19_55390228_+	ncRNA_exonic
CAediting_1391366	chr19_55390261_+	ncRNA_exonic
CAediting_1391367	chr19_55390269_+	ncRNA_exonic
CAediting_1391368	chr19_55390284_+	ncRNA_exonic
CAediting_1391369	chr19_55390291_+	ncRNA_exonic
CAediting_1391370	chr19_55390305_+	ncRNA_exonic
CAediting_1391371	chr19_55390322_+	ncRNA_exonic
CAediting_1391372	chr19_55390331_+	ncRNA_exonic
CAediting_1391373	chr19_55390334_+	ncRNA_exonic
CAediting_1391374	chr19_55390341_+	ncRNA_exonic
CAediting_1391375	chr19_55390346_+	ncRNA_exonic
CAediting_1391376	chr19_55390360_+	ncRNA_exonic
CAediting_1391377	chr19_55390388_+	ncRNA_exonic
CAediting_1391378	chr19_55390414_+	ncRNA_exonic
CAediting_1391379	chr19_55390440_+	ncRNA_exonic
CAediting_1391380	chr19_55390441_+	ncRNA_exonic
CAediting_1391381	chr19_55390444_+	ncRNA_exonic
CAediting_1391382	chr19_55390448_+	ncRNA_exonic
CAediting_1391383	chr19_55390467_+	ncRNA_exonic
CAediting_1391384	chr19_55390521_+	ncRNA_exonic
CAediting_1391385	chr19_55391478_+	ncRNA_exonic
CAediting_1391386	chr19_55392510_+	intronic
CAediting_1391387	chr19_55392736_+	intronic
CAediting_1391388	chr19_55396012_+	intronic
CAediting_1391389	chr19_55396137_+	intronic
CAediting_1391390	chr19_55396144_+	intronic
CAediting_1391391	chr19_55396150_+	intronic
CAediting_1391392	chr19_55396186_+	intronic
CAediting_1391393	chr19_55397080_+	intronic
CAediting_1391394	chr19_55398075_+	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1391344	chr19_55389141_+	SINE	Alu	AluJr
CAediting_1391345	chr19_55389146_+	SINE	Alu	AluJr
CAediting_1391346	chr19_55389149_+	SINE	Alu	AluJr
CAediting_1391347	chr19_55389155_+	SINE	Alu	AluJr
CAediting_1391348	chr19_55389165_+	SINE	Alu	AluJr
CAediting_1391349	chr19_55389174_+	SINE	Alu	AluJr
CAediting_1391350	chr19_55389175_+	SINE	Alu	AluJr
CAediting_1391351	chr19_55389198_+	SINE	Alu	AluJr
CAediting_1391352	chr19_55389220_+	SINE	Alu	AluJr
CAediting_1391353	chr19_55389243_+	SINE	Alu	AluJr
CAediting_1391354	chr19_55389262_+	SINE	Alu	AluJr
CAediting_1391355	chr19_55389275_+	SINE	Alu	AluJr
CAediting_1391356	chr19_55389280_+	SINE	Alu	AluJr
CAediting_1391357	chr19_55389284_+	SINE	Alu	AluJr
CAediting_1391358	chr19_55389285_+	SINE	Alu	AluJr
CAediting_1391359	chr19_55389287_+	SINE	Alu	AluJr
CAediting_1391360	chr19_55389290_+	SINE	Alu	AluJr
CAediting_1391361	chr19_55389300_+	SINE	Alu	AluJr
CAediting_1391362	chr19_55389318_+	SINE	Alu	AluJr
CAediting_1391363	chr19_55389324_+	SINE	Alu	AluJr
CAediting_1391364	chr19_55389331_+	SINE	Alu	AluJr
CAediting_1391365	chr19_55390228_+	SINE	Alu	AluSz
CAediting_1391366	chr19_55390261_+	SINE	Alu	AluSz
CAediting_1391367	chr19_55390269_+	SINE	Alu	AluSz
CAediting_1391368	chr19_55390284_+	SINE	Alu	AluSz
CAediting_1391369	chr19_55390291_+	SINE	Alu	AluSz
CAediting_1391370	chr19_55390305_+	SINE	Alu	AluSz
CAediting_1391371	chr19_55390322_+	SINE	Alu	AluSz
CAediting_1391372	chr19_55390331_+	SINE	Alu	AluSz
CAediting_1391373	chr19_55390334_+	SINE	Alu	AluSz
CAediting_1391374	chr19_55390341_+	SINE	Alu	AluSz
CAediting_1391375	chr19_55390346_+	SINE	Alu	AluSz
CAediting_1391376	chr19_55390360_+	SINE	Alu	AluSz
CAediting_1391377	chr19_55390388_+	SINE	Alu	AluSz
CAediting_1391378	chr19_55390414_+	SINE	Alu	AluSz
CAediting_1391379	chr19_55390440_+	SINE	Alu	AluSz
CAediting_1391380	chr19_55390441_+	SINE	Alu	AluSz
CAediting_1391381	chr19_55390444_+	SINE	Alu	AluSz
CAediting_1391382	chr19_55390448_+	SINE	Alu	AluSz
CAediting_1391383	chr19_55390467_+	SINE	Alu	AluSz
CAediting_1391386	chr19_55392510_+	SINE	Alu	AluJr
CAediting_1391387	chr19_55392736_+	SINE	Alu	AluY
CAediting_1391388	chr19_55396012_+	SINE	Alu	AluJo
CAediting_1391389	chr19_55396137_+	SINE	Alu	AluJo
CAediting_1391390	chr19_55396144_+	SINE	Alu	AluJo
CAediting_1391391	chr19_55396150_+	SINE	Alu	AluJo
CAediting_1391392	chr19_55396186_+	SINE	Alu	AluJo
CAediting_1391393	chr19_55397080_+	SINE	Alu	AluJb
CAediting_1391394	chr19_55398075_+	SINE	Alu	AluSz6

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RNA A-to-I editing events in the alternative splicing sites for RPL28

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000108107.11.RPL28.

Correlation between RNA A-to-I editing and PSI for ENSG00000108107.11.RPL28.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RPL28

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

LIHC.CAediting_1391358.ENSG00000108107.RPL28.png
Soverview

THYM.CAediting_1391349.ENSG00000108107.RPL28.png
Soverview

UCEC.CAediting_1391356.ENSG00000108107.RPL28.png
Soverview

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Protein coding region RNA A-to-I editings for RPL28

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for RPL28

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1391348	chr19_55389165_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6764-5p	55389161	55389166	6mer	55389146	55389167	140.00	-22.11
CAediting_1391348	chr19_55389165_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6840-3p	55389160	55389166	7mer-m8	55389146	55389167	140.00	-19.22
CAediting_1391349	chr19_55389174_+	ENSG00000108107.11	ENST00000344063	hsa-miR-96-3p	55389169	55389175	7mer-m8	55389154	55389176	141.00	-12.18
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-518e-3p	55389271	55389277	7mer-m8	55389258	55389278	154.00	-19.64
CAediting_1391356	chr19_55389280_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3136-3p	55389276	55389283	8mer-1a	55389263	55389283	149.00	-18.53
CAediting_1391356	chr19_55389280_+	ENSG00000108107.11	ENST00000344063	hsa-miR-7155-3p	55389276	55389283	8mer-1a	55389265	55389283	156.00	-21.85
CAediting_1391363	chr19_55389324_+	ENSG00000108107.11	ENST00000344063	hsa-miR-143-5p	55389320	55389326	7mer-m8	55389305	55389327	159.00	-23.53
CAediting_1391366	chr19_55390261_+	ENSG00000108107.11	ENST00000344063	hsa-miR-324-3p	55390257	55390263	7mer-m8	55390242	55390264	142.00	-21.82
CAediting_1391366	chr19_55390261_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4252	55390258	55390264	7mer-m8	55390246	55390265	147.00	-23.02
CAediting_1391366	chr19_55390261_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4793-3p	55390254	55390260	7mer-m8	55390237	55390261	151.00	-21.69
CAediting_1391366	chr19_55390261_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6807-3p	55390256	55390261	6mer	55390238	55390262	151.00	-29.87
CAediting_1391375	chr19_55390346_+	ENSG00000108107.11	ENST00000344063	hsa-miR-100-5p	55390342	55390348	7mer-m8	55390329	55390349	160.00	-20.88
CAediting_1391375	chr19_55390346_+	ENSG00000108107.11	ENST00000344063	hsa-miR-99a-5p	55390342	55390348	7mer-m8	55390329	55390349	160.00	-19.76
CAediting_1391375	chr19_55390346_+	ENSG00000108107.11	ENST00000344063	hsa-miR-99b-5p	55390342	55390348	7mer-m8	55390329	55390349	152.00	-24.40
CAediting_1391378	chr19_55390414_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3940-3p	55390411	55390417	7mer-m8	55390397	55390418	140.00	-18.92
CAediting_1391378	chr19_55390414_+	ENSG00000108107.11	ENST00000344063	hsa-miR-7112-5p	55390408	55390413	6mer	55390393	55390414	144.00	-25.59
CAediting_1391384	chr19_55390521_+	ENSG00000108107.11	ENST00000344063	hsa-miR-2276-5p	55390516	55390522	7mer-m8	55390502	55390523	148.00	-24.08
CAediting_1391384	chr19_55390521_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3921	55390514	55390520	7mer-m8	55390499	55390521	159.00	-21.36
CAediting_1391384	chr19_55390521_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4653-5p	55390514	55390520	7mer-m8	55390498	55390521	151.00	-23.33
CAediting_1391385	chr19_55391478_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3189-3p	55391472	55391478	7mer-m8	55391459	55391479	152.00	-21.70
CAediting_1391385	chr19_55391478_+	ENSG00000108107.11	ENST00000344063	hsa-miR-635	55391471	55391477	7mer-m8	55391456	55391478	140.00	-14.93
CAediting_1391385	chr19_55391478_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6774-5p	55391471	55391477	7mer-m8	55391455	55391478	145.00	-18.48
CAediting_1391385	chr19_55391478_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6813-3p	55391473	55391479	7mer-m8	55391460	55391480	142.00	-14.48
CAediting_1391344	chr19_55389141_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4758-3p	55389137	55389143	7mer-m8	55389122	55389144	154.00	-23.27
CAediting_1391344	chr19_55389141_+	ENSG00000108107.11	ENST00000344063	hsa-miR-874-5p	55389138	55389145	8mer-1a	55389123	55389145	154.00	-22.66
CAediting_1391346	chr19_55389149_+	ENSG00000108107.11	ENST00000344063	hsa-miR-331-3p	55389143	55389149	7mer-m8	55389132	55389150	147.00	-22.69
CAediting_1391346	chr19_55389149_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6771-3p	55389146	55389152	7mer-m8	55389133	55389153	158.00	-26.64
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-151a-5p	55389236	55389242	7mer-m8	55389218	55389243	152.00	-25.40
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-151b	55389236	55389242	7mer-m8	55389226	55389243	150.00	-20.05
CAediting_1391354	chr19_55389262_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6802-3p	55389260	55389266	7mer-m8	55389244	55389267	155.00	-23.40
CAediting_1391357	chr19_55389284_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3615	55389281	55389287	7mer-m8	55389268	55389288	155.00	-27.17
CAediting_1391357	chr19_55389284_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4638-5p	55389279	55389286	8mer-1a	55389266	55389286	150.00	-18.86
CAediting_1391360	chr19_55389290_+	ENSG00000108107.11	ENST00000344063	hsa-miR-342-3p	55389287	55389293	7mer-m8	55389272	55389294	140.00	-15.94
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-10396a-5p	55389312	55389318	7mer-m8	55389300	55389319	154.00	-32.03
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-10396b-5p	55389313	55389320	8mer-1a	55389300	55389320	159.00	-31.27
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-1908-5p	55389313	55389320	8mer-1a	55389300	55389320	140.00	-20.72
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4508	55389311	55389317	7mer-m8	55389299	55389318	146.00	-29.44
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-663a	55389313	55389320	8mer-1a	55389300	55389320	151.00	-30.02
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6787-5p	55389313	55389320	8mer-1a	55389297	55389320	154.00	-31.49
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-744-5p	55389312	55389318	7mer-m8	55389296	55389319	166.00	-31.34
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-25-5p	55390286	55390292	7mer-m8	55390269	55390293	149.00	-24.00
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-658	55390285	55390291	7mer-m8	55390266	55390292	153.00	-28.47
CAediting_1391370	chr19_55390305_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4539	55390299	55390304	6mer	55390286	55390305	141.00	-19.05
CAediting_1391370	chr19_55390305_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6078	55390301	55390308	8mer-1a	55390289	55390308	148.00	-20.43
CAediting_1391372	chr19_55390331_+	ENSG00000108107.11	ENST00000344063	hsa-miR-1247-3p	55390325	55390331	7mer-m8	55390310	55390332	160.00	-27.57
CAediting_1391373	chr19_55390334_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4691-3p	55390331	55390337	7mer-m8	55390311	55390338	150.00	-26.36
CAediting_1391376	chr19_55390360_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4466	55390357	55390363	7mer-m8	55390346	55390364	141.00	-23.29
CAediting_1391376	chr19_55390360_+	ENSG00000108107.11	ENST00000344063	hsa-miR-598-5p	55390354	55390359	6mer	55390339	55390360	143.00	-26.66
CAediting_1391376	chr19_55390360_+	ENSG00000108107.11	ENST00000344063	hsa-miR-675-5p	55390357	55390363	7mer-m8	55390343	55390364	161.00	-27.69
CAediting_1391382	chr19_55390448_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3937	55390445	55390451	7mer-m8	55390428	55390452	144.00	-21.90
CAediting_1391352	chr19_55389220_+	ENSG00000108107.11	ENST00000344063	hsa-miR-10400-5p	55389218	55389224	7mer-m8	55389206	55389225	143.00	-20.94
CAediting_1391352	chr19_55389220_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4467	55389218	55389224	7mer-m8	55389204	55389225	140.00	-17.88
CAediting_1391352	chr19_55389220_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6722-5p	55389215	55389221	7mer-m8	55389205	55389222	163.00	-27.42
CAediting_1391364	chr19_55389331_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4743-5p	55389327	55389333	7mer-m8	55389312	55389334	152.00	-23.22
CAediting_1391367	chr19_55390269_+	ENSG00000108107.11	ENST00000344063	hsa-miR-548ao-3p	55390266	55390272	7mer-m8	55390250	55390273	151.00	-21.24
CAediting_1391383	chr19_55390467_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3189-3p	55390461	55390467	7mer-m8	55390445	55390468	153.00	-26.36
CAediting_1391383	chr19_55390467_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6813-3p	55390462	55390468	7mer-m8	55390449	55390469	140.00	-11.59

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-1184	55389294	55389300	7mer-m8	55389276	55389301	148	-21.25
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-1184	55389294	55389300	7mer-m8	55389276	55389301	148	-21.25
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-1184	55389294	55389300	7mer-m8	55389276	55389301	148	-21.25
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-12114	55390287	55390293	7mer-m8	55390272	55390294	155	-25.76
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-12119	55389238	55389244	7mer-m8	55389221	55389245	152	-27.03
CAediting_1391384	chr19_55390521_+	ENSG00000108107.11	ENST00000344063	hsa-miR-1237-3p	55390516	55390522	7mer-m8	55390503	55390523	142	-14.58
CAediting_1391384	chr19_55390521_+	ENSG00000108107.11	ENST00000344063	hsa-miR-1245b-5p	55390519	55390525	7mer-m8	55390506	55390526	155	-13.82
CAediting_1391368	chr19_55390284_+	ENSG00000108107.11	ENST00000344063	hsa-miR-17-3p	55390278	55390284	7mer-m8	55390265	55390285	153	-18.99
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-301b-5p	55389240	55389245	6mer	55389225	55389246	140	-19.3
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-302e	55389271	55389277	7mer-m8	55389262	55389278	146	-15.66
CAediting_1391348	chr19_55389165_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3135a	55389161	55389168	8mer-1a	55389149	55389168	152	-18.69
CAediting_1391384	chr19_55390521_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3142	55390519	55390525	7mer-m8	55390506	55390526	153	-21.66
CAediting_1391345	chr19_55389146_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3176	55389140	55389146	7mer-m8	55389129	55389147	140	-15.14
CAediting_1391378	chr19_55390414_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3187-5p	55390408	55390414	7mer-m8	55390396	55390415	152	-28.58
CAediting_1391366	chr19_55390261_+	ENSG00000108107.11	ENST00000344063	hsa-miR-32-5p	55390255	55390261	7mer-m8	55390242	55390262	150	-13.87
CAediting_1391366	chr19_55390261_+	ENSG00000108107.11	ENST00000344063	hsa-miR-363-3p	55390255	55390261	7mer-m8	55390242	55390262	148	-16.01
CAediting_1391364	chr19_55389331_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3652	55389327	55389333	7mer-m8	55389315	55389334	152	-21.68
CAediting_1391382	chr19_55390448_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3665	55390446	55390452	7mer-m8	55390436	55390453	142	-16.5
CAediting_1391366	chr19_55390261_+	ENSG00000108107.11	ENST00000344063	hsa-miR-367-3p	55390255	55390261	7mer-m8	55390240	55390262	152	-18.47
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3689d	55390289	55390295	7mer-m8	55390274	55390296	143	-15.76
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3689d	55390289	55390295	7mer-m8	55390274	55390296	143	-15.76
CAediting_1391347	chr19_55389155_+	ENSG00000108107.11	ENST00000344063	hsa-miR-371a-5p	55389149	55389156	8mer-1a	55389137	55389156	150	-18.15
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-373-3p	55389271	55389277	7mer-m8	55389256	55389278	154	-19.03
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3921	55389239	55389245	7mer-m8	55389224	55389246	144	-16.71
CAediting_1391345	chr19_55389146_+	ENSG00000108107.11	ENST00000344063	hsa-miR-3922-3p	55389140	55389146	7mer-m8	55389128	55389147	144	-17.92
CAediting_1391363	chr19_55389324_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4280	55389321	55389327	7mer-m8	55389308	55389328	151	-16.93
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4418	55389295	55389301	7mer-m8	55389286	55389302	148	-21.39
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4443	55390284	55390290	7mer-m8	55390274	55390291	143	-17.78
CAediting_1391376	chr19_55390360_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4455	55390358	55390365	8mer-1a	55390350	55390365	146	-17.17
CAediting_1391363	chr19_55389324_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4460	55389317	55389323	7mer-m8	55389303	55389324	144	-9.81
CAediting_1391371	chr19_55390322_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4478	55390319	55390325	7mer-m8	55390311	55390326	149	-25.05
CAediting_1391371	chr19_55390322_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4649-3p	55390316	55390322	7mer-m8	55390303	55390323	140	-14.11
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4653-5p	55389239	55389245	7mer-m8	55389227	55389246	144	-18.24
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4689	55389236	55389242	7mer-m8	55389224	55389243	142	-24.23
CAediting_1391351	chr19_55389198_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4735-5p	55389196	55389202	7mer-m8	55389182	55389203	142	-7.59
CAediting_1391352	chr19_55389220_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4746-3p	55389217	55389223	7mer-m8	55389204	55389224	155	-25.2
CAediting_1391348	chr19_55389165_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4774-3p	55389163	55389169	7mer-m8	55389149	55389170	150	-13.72
CAediting_1391351	chr19_55389198_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4775	55389195	55389201	7mer-m8	55389181	55389202	151	-8.85
CAediting_1391368	chr19_55390284_+	ENSG00000108107.11	ENST00000344063	hsa-miR-485-5p	55390282	55390288	7mer-m8	55390269	55390289	153	-17.86
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-509-3-5p	55389295	55389301	7mer-m8	55389282	55389302	145	-17.63
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-509-5p	55389295	55389301	7mer-m8	55389282	55389302	142	-14.19
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-509-5p	55389295	55389301	7mer-m8	55389282	55389302	142	-14.19
CAediting_1391344	chr19_55389141_+	ENSG00000108107.11	ENST00000344063	hsa-miR-513b-5p	55389134	55389140	7mer-m8	55389123	55389141	142	-12.17
CAediting_1391378	chr19_55390414_+	ENSG00000108107.11	ENST00000344063	hsa-miR-5189-5p	55390408	55390414	7mer-m8	55390394	55390415	152	-22.11
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-520a-3p	55389271	55389277	7mer-m8	55389257	55389278	154	-15.14
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-520b-3p	55389271	55389277	7mer-m8	55389258	55389278	150	-15.59
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-520c-3p	55389271	55389277	7mer-m8	55389257	55389278	150	-17.44
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-520d-3p	55389271	55389277	7mer-m8	55389257	55389278	154	-15.47
CAediting_1391355	chr19_55389275_+	ENSG00000108107.11	ENST00000344063	hsa-miR-520e-3p	55389271	55389277	7mer-m8	55389256	55389278	153	-18.13
CAediting_1391373	chr19_55390334_+	ENSG00000108107.11	ENST00000344063	hsa-miR-5690	55390331	55390337	7mer-m8	55390318	55390338	145	-16.75
CAediting_1391351	chr19_55389198_+	ENSG00000108107.11	ENST00000344063	hsa-miR-590-3p	55389194	55389201	8mer-1a	55389181	55389201	149	-6.45
CAediting_1391378	chr19_55390414_+	ENSG00000108107.11	ENST00000344063	hsa-miR-661	55390410	55390416	7mer-m8	55390394	55390417	141	-19.17
CAediting_1391377	chr19_55390388_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6728-3p	55390384	55390391	8mer-1a	55390371	55390391	140	-12.89
CAediting_1391382	chr19_55390448_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6769a-5p	55390443	55390449	7mer-m8	55390430	55390450	151	-21.93
CAediting_1391382	chr19_55390448_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6769b-5p	55390443	55390449	7mer-m8	55390424	55390450	151	-23.71
CAediting_1391354	chr19_55389262_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6787-3p	55389257	55389262	6mer	55389240	55389263	142	-24.4
CAediting_1391347	chr19_55389155_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6843-3p	55389153	55389159	7mer-m8	55389141	55389160	152	-21.51
CAediting_1391347	chr19_55389155_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6848-3p	55389153	55389159	7mer-m8	55389143	55389160	142	-16.5
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6851-5p	55390289	55390295	7mer-m8	55390270	55390296	154	-31.77
CAediting_1391353	chr19_55389243_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6858-5p	55389236	55389242	7mer-m8	55389220	55389243	158	-25.96
CAediting_1391344	chr19_55389141_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6878-3p	55389139	55389145	7mer-m8	55389126	55389146	140	-16.34
CAediting_1391345	chr19_55389146_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6878-3p	55389139	55389145	7mer-m8	55389126	55389146	140	-16.34
CAediting_1391368	chr19_55390284_+	ENSG00000108107.11	ENST00000344063	hsa-miR-6884-5p	55390282	55390288	7mer-m8	55390267	55390289	146	-20.16
CAediting_1391361	chr19_55389300_+	ENSG00000108107.11	ENST00000344063	hsa-miR-7156-3p	55389293	55389299	7mer-m8	55389278	55389300	145	-23.24
CAediting_1391371	chr19_55390322_+	ENSG00000108107.11	ENST00000344063	hsa-miR-7160-5p	55390317	55390323	7mer-m8	55390304	55390324	146	-20.4
CAediting_1391369	chr19_55390291_+	ENSG00000108107.11	ENST00000344063	hsa-miR-7847-3p	55390285	55390291	7mer-m8	55390270	55390292	146	-20.12
CAediting_1391374	chr19_55390341_+	ENSG00000108107.11	ENST00000344063	hsa-miR-7977	55390334	55390340	7mer-m8	55390324	55390341	142	-14.06
CAediting_1391362	chr19_55389318_+	ENSG00000108107.11	ENST00000344063	hsa-miR-92a-2-5p	55389313	55389320	8mer-1a	55389297	55389320	147	-21.43
CAediting_1391378	chr19_55390414_+	ENSG00000108107.11	ENST00000344063	hsa-miR-939-3p	55390409	55390415	7mer-m8	55390396	55390416	140	-15.63

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000108107.11	ENST00000344063	hsa-miR-605-3p	55391100	55391107	8mer-1a	55391085	55391107	167	-18.35
CAediting_980496	chr14_31014685_-	ENSG00000108107.11	ENST00000344063	hsa-miR-624-3p	55389056	55389062	7mer-m8	55389043	55389063	140	-13.45
CAediting_393	chr1_1167164_+	ENSG00000108107.11	ENST00000344063	hsa-miR-200b-3p	55391196	55391202	7mer-m8	55391182	55391203	164	-19.42
CAediting_688080	chr9_63819626_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4477b	55391616	55391622	7mer-m8	55391603	55391623	153	-13.82
CAediting_1229413	chr17_67471544_+	ENSG00000108107.11	ENST00000431533	hsa-miR-548aa	55387009	55387016	8mer-1a	55386991	55387016	147	-15.57
CAediting_1054808	chr15_66496985_-	ENSG00000108107.11	ENST00000344063	hsa-miR-4512	55390570	55390577	8mer-1a	55390555	55390577	143	-21.51
CAediting_1229415	chr17_67471547_+	ENSG00000108107.11	ENST00000344063	hsa-miR-548aa	55390596	55390602	7mer-m8	55390580	55390603	152	-12.59
CAediting_1229415	chr17_67471547_+	ENSG00000108107.11	ENST00000344063	hsa-miR-548aa	55388362	55388368	7mer-m8	55388344	55388369	156	-13.68
CAediting_1368054	chr19_46709310_-	ENSG00000108107.11	ENST00000344063	hsa-miR-320e	55389664	55389670	7mer-m8	55389655	55389671	153	-18.19
CAediting_1368054	chr19_46709310_-	ENSG00000108107.11	ENST00000344063	hsa-miR-320e	55390363	55390370	8mer-1a	55390352	55390370	151	-18.38
CAediting_1368054	chr19_46709310_-	ENSG00000108107.11	ENST00000344063	hsa-miR-320e	55391204	55391211	8mer-1a	55391194	55391211	145	-17.24
CAediting_1368054	chr19_46709310_-	ENSG00000108107.11	ENST00000344063	hsa-miR-320e	55391261	55391267	7mer-m8	55391251	55391268	153	-22.28
CAediting_1368054	chr19_46709310_-	ENSG00000108107.11	ENST00000344063	hsa-miR-320e	55391408	55391414	7mer-m8	55391400	55391415	148	-20.06
CAediting_1368054	chr19_46709310_-	ENSG00000108107.11	ENST00000344063	hsa-miR-320e	55389232	55389238	7mer-m8	55389222	55389239	147	-21.31
CAediting_77128	chr1_85133844_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4423-3p	55391722	55391728	7mer-m8	55391709	55391729	153	-17.76
CAediting_228905	chr2_188297554_+	ENSG00000108107.11	ENST00000344063	hsa-miR-561-3p	55388453	55388459	7mer-m8	55388434	55388460	146	-16.2
CAediting_573001	chr7_92204086_-	ENSG00000108107.11	ENST00000344063	hsa-miR-1285-5p	55389175	55389181	7mer-1a	55389161	55389181	147	-24.93
CAediting_1229415	chr17_67471547_+	ENSG00000108107.11	ENST00000560583	hsa-miR-548aa	55388362	55388368	7mer-m8	55388344	55388369	156	-13.68
CAediting_228905	chr2_188297554_+	ENSG00000108107.11	ENST00000560583	hsa-miR-561-3p	55388453	55388459	7mer-m8	55388434	55388460	146	-16.2
CAediting_1229415	chr17_67471547_+	ENSG00000108107.11	ENST00000559463	hsa-miR-548aa	55388362	55388368	7mer-m8	55388344	55388369	156	-13.68
CAediting_1229415	chr17_67471547_+	ENSG00000108107.11	ENST00000558131	hsa-miR-548aa	55388362	55388368	7mer-m8	55388344	55388369	156	-13.68
CAediting_1229413	chr17_67471544_+	ENSG00000108107.11	ENST00000558752	hsa-miR-548aa	55387009	55387016	8mer-1a	55386991	55387016	147	-15.57

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000108107.11	ENST00000344063	hsa-miR-1304-3p	55389353	55389359	7mer-m8	55389340	55389360	146	-16.22
CAediting_393	chr1_1167164_+	ENSG00000108107.11	ENST00000344063	hsa-miR-200b-3p	55390369	55390375	7mer-m8	55390354	55390376	151	-17.48
CAediting_1368054	chr19_46709310_-	ENSG00000108107.11	ENST00000344063	hsa-miR-320e	55390914	55390920	7mer-m8	55390905	55390921	149	-18.37
CAediting_688080	chr9_63819626_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4477b	55390528	55390534	7mer-m8	55390510	55390535	152	-13.78
CAediting_688081	chr9_63819627_+	ENSG00000108107.11	ENST00000344063	hsa-miR-4477b	55390528	55390534	7mer-m8	55390510	55390535	152	-13.78
CAediting_980496	chr14_31014685_-	ENSG00000108107.11	ENST00000344063	hsa-miR-624-3p	55388467	55388473	7mer-m8	55388453	55388474	142	-10.06
CAediting_1351755	chr19_40282625_-	ENSG00000108107.11	ENST00000344063	hsa-miR-641	55391631	55391636	6mer	55391611	55391637	143	-16.02
CAediting_1351755	chr19_40282625_-	ENSG00000108107.11	ENST00000344063	hsa-miR-641	55391800	55391806	7mer-m8	55391780	55391807	151	-18.59
CAediting_1399425	chr20_1392958_-	ENSG00000108107.11	ENST00000344063	hsa-miR-6869-5p	55391675	55391681	7mer-m8	55391661	55391682	153	-20.67
CAediting_980496	chr14_31014685_-	ENSG00000108107.11	ENST00000560583	hsa-miR-624-3p	55388467	55388473	7mer-m8	55388453	55388474	142	-10.06

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RPL28

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for RPL28

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_1391348	chr19_55389165_+	.	.	0.00159616184590361	0.16510984720576	0.00192782533503823	0.162247024298122
COAD	CAediting_1391348	chr19_55389165_+	0.000670734165458274	0.235078484456542	.	.	.	.
LUSC	CAediting_1391348	chr19_55389165_+	0.00390051587438819	0.203723417273847	.	.	.	.
PRAD	CAediting_1391348	chr19_55389165_+	0.0105368040342075	0.162812479586432	.	.	.	.
HNSC	CAediting_1391348	chr19_55389165_+	0.0320199804067137	0.145284788490449	.	.	.	.
LAML	CAediting_1391348	chr19_55389165_+	0.0222713686155682	0.193087055148448	.	.	.	.
OV	CAediting_1391348	chr19_55389165_+	0.0129570803462945	0.154228136709648	.	.	.	.
SKCM	CAediting_1391348	chr19_55389165_+	3.85121259277685e-05	0.257731848426168	.	.	.	.
READ	CAediting_1391348	chr19_55389165_+	0.0092925535697847	0.289122928985336	.	.	.	.
LGG	CAediting_1391349	chr19_55389174_+	0.00738352076663369	0.163311213133686	.	.	0.0126085711059384	0.152206828324462
BRCA	CAediting_1391349	chr19_55389174_+	4.61380592126658e-06	0.255277620030803	.	.	.	.
CESC	CAediting_1391349	chr19_55389174_+	0.000324567896771265	0.475110538945556	.	.	0.000826475458540195	0.445605961597576
COAD	CAediting_1391349	chr19_55389174_+	0.0172117001931774	0.219888502559943	.	.	0.0348671501218358	0.195274743648085
LUSC	CAediting_1391349	chr19_55389174_+	0.00278954394343535	0.243309510212957	0.000408743503701369	0.285887546736766	.	.
GBM	CAediting_1391349	chr19_55389174_+	0.0179910720601493	0.265607066196475	.	.	.	.
STAD	CAediting_1391349	chr19_55389174_+	.	.	0.00451886145041739	0.179384762960533	.	.
KIRC	CAediting_1391349	chr19_55389174_+	0.000220821057048217	0.243361131665626	.	.	.	.
OV	CAediting_1391349	chr19_55389174_+	0.0188182800219	0.154469320775441	.	.	.	.
SKCM	CAediting_1391349	chr19_55389174_+	6.40000606714471e-06	0.32835549766182	.	.	.	.
SARC	CAediting_1391349	chr19_55389174_+	0.00160218658935456	0.408602015907313	.	.	.	.
LGG	CAediting_1391356	chr19_55389280_+	.	.	3.18357199910577e-07	0.268421559879943	0.0354380896255744	0.112152169553282
BRCA	CAediting_1391356	chr19_55389280_+	.	.	0.00707447736809879	0.135835839741219	.	.
GBM	CAediting_1391356	chr19_55389280_+	.	.	.	.	0.000766504163498903	0.341126766059584
STAD	CAediting_1391356	chr19_55389280_+	.	.	1.63980026741751e-05	0.31514823887954	0.0343501591860921	0.157822380216737
KIRP	CAediting_1391356	chr19_55389280_+	.	.	0.000399011367237755	0.477209825646265	.	.
ESCA	CAediting_1391356	chr19_55389280_+	.	.	0.00734717233239664	0.282337420558245	.	.
SKCM	CAediting_1391356	chr19_55389280_+	.	.	4.99902214886032e-05	0.268693300064222	.	.
LGG	CAediting_1391358	chr19_55389285_+	.	.	4.14159577910708e-08	0.273981885020635	0.000475298232532969	0.176570371288914
BRCA	CAediting_1391358	chr19_55389285_+	0.000824959089670035	0.150601356148931	.	.	.	.
CESC	CAediting_1391358	chr19_55389285_+	0.020188178294668	0.253092740629095	.	.	.	.
LUAD	CAediting_1391358	chr19_55389285_+	0.00553761332964523	0.221118012873826	.	.	.	.
COAD	CAediting_1391358	chr19_55389285_+	0.020645737986867	0.180616903207001	.	.	.	.
LUSC	CAediting_1391358	chr19_55389285_+	1.70532081845825e-06	0.320346546481431	.	.	0.0347432948178185	0.144416448090348
GBM	CAediting_1391358	chr19_55389285_+	0.0207750433763269	0.208304922186949	.	.	.	.
HNSC	CAediting_1391358	chr19_55389285_+	8.38948977605772e-07	0.325620647166167	.	.	.	.
STAD	CAediting_1391358	chr19_55389285_+	.	.	0.000513142233932555	0.209637756742437	.	.
THCA	CAediting_1391358	chr19_55389285_+	0.0064124414054895	0.168011883082207	0.0118997807142991	0.155183117569911	.	.
KIRC	CAediting_1391358	chr19_55389285_+	0.0114170011465354	0.143510865254857	0.0163016134248307	0.136342763749713	.	.
KIRP	CAediting_1391358	chr19_55389285_+	.	.	0.00315958446497435	0.360709077378119	.	.
ESCA	CAediting_1391358	chr19_55389285_+	0.0210073657512238	0.197763384986008	0.0107734014467874	0.218032858467828	.	.
PCPG	CAediting_1391358	chr19_55389285_+	0.0243664843636297	0.276962491929242	0.0229651143542694	0.279644993061197	.	.
SKCM	CAediting_1391358	chr19_55389285_+	0.0123276006139406	0.158075709536971	.	.	.	.
SARC	CAediting_1391358	chr19_55389285_+	0.0273404123491697	0.233952538721571	.	.	.	.
BRCA	CAediting_1391366	chr19_55390261_+	.	.	0.00960252900984529	0.297247431612216	.	.
ESCA	CAediting_1391366	chr19_55390261_+	.	.	0.00636743393459355	0.340219311233604	.	.
BRCA	CAediting_1391375	chr19_55390346_+	0.0477690519628551	0.172632321681323	.	.	.	.
SKCM	CAediting_1391375	chr19_55390346_+	0.0021439837691936	0.412518546480931	.	.	.	.
LUAD	CAediting_1391378	chr19_55390414_+	0.034081899339147	0.271815183844868	.	.	.	.
THCA	CAediting_1391378	chr19_55390414_+	0.0166172670194109	0.178326912179701	.	.	.	.
SKCM	CAediting_1391378	chr19_55390414_+	0.00196616245182429	0.320308818374248	.	.	.	.

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Relation with cancer stages for RPL28

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
ESCA	clinical_stage	CAediting_1391366	chr19_55390261_+	0.0162746415005946	-0.557285248872
HNSC	clinical_stage	CAediting_1391358	chr19_55389285_+	0.0248558802787622	0.153004525889258
HNSC	pathologic_stage	CAediting_1391348	chr19_55389165_+	0.027881954145563	0.163027720174731
OV	clinical_stage	CAediting_1391349	chr19_55389174_+	0.034974433304269	0.139121678673409
SKCM	pathologic_stage	CAediting_1391356	chr19_55389280_+	0.0393359674909229	-0.14770580924232
STAD	pathologic_stage	CAediting_1391348	chr19_55389165_+	0.0376554480047246	0.126576725650207

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Relation with survival for RPL28

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
GBM	CAediting_1391349	chr19_55389174_+	0.0230169321151665	0.0429753	0.0987894
ESCA	CAediting_1391358	chr19_55389285_+	0.0100081188397195	0.00241452	102.83

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RelatedDrugs for RPL28

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for RPL28

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
RPL28	C0043094	Weight Gain	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene