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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: RPL3 (CAeditome ID:6122) |
Gene summary for RPL3 |
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Gene information | Gene symbol | RPL3 | Gene ID | 6122 |
Gene name | ribosomal protein L3 | |
Synonyms | ASC-1|L3|TARBP-B | |
Cytomap | 22q13.1 | |
Type of gene | protein-coding | |
Description | 60S ribosomal protein L3HIV-1 TAR RNA-binding protein Blarge ribosomal subunit protein uL3 | |
Modification date | 20210518 | |
UniProtAcc | P39023 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
RPL3 | GO:0003735 | 60S ribosomal protein L3 | 23636399 |
RPL3 | GO:0005730 | 60S ribosomal protein L3 | 0000052 |
RPL3 | GO:0005730 | 60S ribosomal protein L3 | 16963496 |
RPL3 | GO:0005829 | 60S ribosomal protein L3 | 0000052 |
RPL3 | GO:0022626 | 60S ribosomal protein L3 | 23636399 |
RPL3 | GO:0032991 | 60S ribosomal protein L3 | 23349634 |
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RNA A-to-I events for RPL3 |
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CAediting_1483219(39318397, -), |
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RNA editing positional annotations for RPL3 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_1483219 | chr22_39318397_- | ncRNA_exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for RPL3 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RPL3 |
![]() * The grey color means N/A. |
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BRCA.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
CESC.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
ESCA.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
LGG.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
LIHC.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
OV.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
READ.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
STAD.CAediting_1483219.ENSG00000100316.RPL3.png ![]() |
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Protein coding region RNA A-to-I editings for RPL3 |
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The effects of the RNA editing to the miRNA binding sites for RPL3 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for RPL3 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for RPL3 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for RPL3 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
CESC | clinical_stage | CAediting_1483219 | chr22_39318397_- | 0.0318759823442153 | -0.206665384519373 |
TGCT | pathologic_stage | CAediting_1483219 | chr22_39318397_- | 0.0494415837595833 | 0.308847968760163 |
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Relation with survival for RPL3 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for RPL3 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
RPL3 | P39023 | DB04865 | Omacetaxine mepesuccinate | 60S ribosomal protein L3 | SmallMoleculeDrug | approved|investigational |
RPL3 | P39023 | DB09092 | Xanthinol | 60S ribosomal protein L3 | SmallMoleculeDrug | approved|withdrawn |
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RelatedDiseases for RPL3 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
RPL3 | C0007097 | Carcinoma | 1 | CTD_human |
RPL3 | C0024667 | Animal Mammary Neoplasms | 1 | CTD_human |
RPL3 | C0024668 | Mammary Neoplasms, Experimental | 1 | CTD_human |
RPL3 | C0205696 | Anaplastic carcinoma | 1 | CTD_human |
RPL3 | C0205697 | Carcinoma, Spindle-Cell | 1 | CTD_human |
RPL3 | C0205698 | Undifferentiated carcinoma | 1 | CTD_human |
RPL3 | C0205699 | Carcinomatosis | 1 | CTD_human |
RPL3 | C1257925 | Mammary Carcinoma, Animal | 1 | CTD_human |