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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: RFX3 (CAeditome ID:5991)

Gene summary for RFX3

check button Gene summary
Gene informationGene symbol

RFX3

Gene ID

5991

Gene nameregulatory factor X3
Synonyms-
Cytomap

9p24.2

Type of geneprotein-coding
Descriptiontranscription factor RFX3DNA binding protein RFX3regulatory factor X, 3 (influences HLA class II expression)
Modification date20210518
UniProtAcc

P48380

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
RFX3

GO:0000976

Transcription factor RFX3

20148032

RFX3

GO:1990837

Transcription factor RFX3

28473536

RFX3

GO:0045892

Transcription factor RFX3

12411430

RFX3

GO:0045893

Transcription factor RFX3

20148032

RFX3

GO:0000785

Transcription factor RFX3

20413507


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RNA A-to-I events for RFX3

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000080298.14
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_674430(3221710, -), CAediting_674431(3238869, -), CAediting_674432(3244107, -), CAediting_674433(3244167, -), CAediting_674434(3244185, -), CAediting_674435(3244209, -), CAediting_674436(3244210, -), CAediting_674437(3244214, -), CAediting_674438(3326554, -), CAediting_674439(3326606, -), CAediting_674440(3326712, -), CAediting_674441(3364155, -), CAediting_674442(3365979, -), CAediting_674443(3372779, -), CAediting_674444(3372782, -), CAediting_674445(3378677, -), CAediting_674446(3424084, -), CAediting_674447(3424121, -), CAediting_674448(3424537, -), CAediting_674449(3424539, -), CAediting_674450(3424556, -), CAediting_674451(3424565, -), CAediting_674452(3424566, -), CAediting_674453(3424627, -), CAediting_674454(3424632, -), CAediting_674455(3425012, -), CAediting_674456(3425038, -), CAediting_674457(3425057, -), CAediting_674458(3425224, -), CAediting_674459(3426704, -), CAediting_674460(3448657, -), CAediting_674461(3448679, -), CAediting_674462(3448702, -), CAediting_674463(3448719, -), CAediting_674464(3448792, -), CAediting_674465(3448799, -), CAediting_674466(3449597, -), CAediting_674467(3449602, -), CAediting_674468(3449725, -), CAediting_674469(3449769, -), CAediting_674470(3449830, -), CAediting_674471(3449842, -), CAediting_674472(3452334, -), CAediting_674473(3452507, -), CAediting_674474(3452549, -), CAediting_674475(3465423, -), CAediting_674476(3465428, -), CAediting_674477(3465429, -), CAediting_674478(3465523, -), CAediting_674479(3470367, -), CAediting_674480(3470382, -), CAediting_674481(3470383, -), CAediting_674482(3470387, -), CAediting_674483(3470404, -), CAediting_674484(3470411, -), CAediting_674485(3470412, -), CAediting_674486(3470423, -), CAediting_674487(3470430, -), CAediting_674488(3470459, -), CAediting_674489(3470479, -), CAediting_674490(3470530, -), CAediting_674491(3470532, -), CAediting_674492(3470533, -), CAediting_674493(3470556, -), CAediting_674494(3470583, -), CAediting_674495(3470599, -), CAediting_674496(3470600, -), CAediting_674497(3474840, -), CAediting_674498(3474983, -), CAediting_674499(3484983, -), CAediting_674500(3487079, -), CAediting_674501(3487083, -), CAediting_674502(3487106, -), CAediting_674503(3487129, -), CAediting_674504(3501579, -), CAediting_674505(3501617, -), CAediting_674506(3501622, -), CAediting_674507(3501629, -), CAediting_674508(3501633, -), CAediting_674509(3501653, -), CAediting_674510(3501654, -), CAediting_674511(3501662, -), CAediting_674512(3501689, -), CAediting_674513(3501694, -), CAediting_674514(3501695, -), CAediting_674515(3501722, -), CAediting_674516(3501727, -), CAediting_674517(3501751, -), CAediting_674518(3501752, -), CAediting_674519(3501760, -), CAediting_674520(3501761, -), CAediting_674521(3501770, -), CAediting_674522(3501775, -), CAediting_674523(3501788, -), CAediting_674524(3501789, -), CAediting_674525(3501813, -), CAediting_674526(3501821, -), CAediting_674527(3501829, -), CAediting_674528(3501830, -), CAediting_674529(3501836, -), CAediting_674530(3501838, -), CAediting_674531(3501848, -), CAediting_674532(3501865, -), CAediting_674533(3501866, -), CAediting_674534(3501867, -), CAediting_674535(3501995, -), CAediting_674536(3502058, -), CAediting_674537(3502062, -), CAediting_674538(3502137, -), CAediting_674539(3502196, -), CAediting_674540(3502252, -), CAediting_674541(3519994, -), CAediting_674542(3520048, -), CAediting_674543(3520058, -), CAediting_674544(3520064, -), CAediting_674545(3520072, -), CAediting_674546(3520104, -), CAediting_674547(3520106, -), CAediting_674548(3520107, -), CAediting_674549(3520705, -), CAediting_674550(3520754, -), CAediting_674551(3520765, -), CAediting_674552(3520803, -), CAediting_674553(3520807, -), CAediting_674554(3520813, -),

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RNA editing positional annotations for RFX3 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_674430chr9_3221710_-UTR3
CAediting_674431chr9_3238869_-intronic
CAediting_674432chr9_3244107_-intronic
CAediting_674433chr9_3244167_-intronic
CAediting_674434chr9_3244185_-intronic
CAediting_674435chr9_3244209_-intronic
CAediting_674436chr9_3244210_-intronic
CAediting_674437chr9_3244214_-intronic
CAediting_674438chr9_3326554_-intronic
CAediting_674439chr9_3326606_-intronic
CAediting_674440chr9_3326712_-intronic
CAediting_674441chr9_3364155_-intronic
CAediting_674442chr9_3365979_-intronic
CAediting_674443chr9_3372779_-intronic
CAediting_674444chr9_3372782_-intronic
CAediting_674445chr9_3378677_-intronic
CAediting_674446chr9_3424084_-intronic
CAediting_674447chr9_3424121_-intronic
CAediting_674448chr9_3424537_-intronic
CAediting_674449chr9_3424539_-intronic
CAediting_674450chr9_3424556_-intronic
CAediting_674451chr9_3424565_-intronic
CAediting_674452chr9_3424566_-intronic
CAediting_674453chr9_3424627_-intronic
CAediting_674454chr9_3424632_-intronic
CAediting_674455chr9_3425012_-intronic
CAediting_674456chr9_3425038_-intronic
CAediting_674457chr9_3425057_-intronic
CAediting_674458chr9_3425224_-intronic
CAediting_674459chr9_3426704_-intronic
CAediting_674460chr9_3448657_-intronic
CAediting_674461chr9_3448679_-intronic
CAediting_674462chr9_3448702_-intronic
CAediting_674463chr9_3448719_-intronic
CAediting_674464chr9_3448792_-intronic
CAediting_674465chr9_3448799_-intronic
CAediting_674466chr9_3449597_-intronic
CAediting_674467chr9_3449602_-intronic
CAediting_674468chr9_3449725_-intronic
CAediting_674469chr9_3449769_-intronic
CAediting_674470chr9_3449830_-intronic
CAediting_674471chr9_3449842_-intronic
CAediting_674472chr9_3452334_-exonic
CAediting_674473chr9_3452507_-intronic
CAediting_674474chr9_3452549_-intronic
CAediting_674475chr9_3465423_-intronic
CAediting_674476chr9_3465428_-intronic
CAediting_674477chr9_3465429_-intronic
CAediting_674478chr9_3465523_-intronic
CAediting_674479chr9_3470367_-intronic
CAediting_674480chr9_3470382_-intronic
CAediting_674481chr9_3470383_-intronic
CAediting_674482chr9_3470387_-intronic
CAediting_674483chr9_3470404_-intronic
CAediting_674484chr9_3470411_-intronic
CAediting_674485chr9_3470412_-intronic
CAediting_674486chr9_3470423_-intronic
CAediting_674487chr9_3470430_-intronic
CAediting_674488chr9_3470459_-intronic
CAediting_674489chr9_3470479_-intronic
CAediting_674490chr9_3470530_-intronic
CAediting_674491chr9_3470532_-intronic
CAediting_674492chr9_3470533_-intronic
CAediting_674493chr9_3470556_-intronic
CAediting_674494chr9_3470583_-intronic
CAediting_674495chr9_3470599_-intronic
CAediting_674496chr9_3470600_-intronic
CAediting_674497chr9_3474840_-intronic
CAediting_674498chr9_3474983_-intronic
CAediting_674499chr9_3484983_-intronic
CAediting_674500chr9_3487079_-intronic
CAediting_674501chr9_3487083_-intronic
CAediting_674502chr9_3487106_-intronic
CAediting_674503chr9_3487129_-intronic
CAediting_674504chr9_3501579_-intronic
CAediting_674505chr9_3501617_-intronic
CAediting_674506chr9_3501622_-intronic
CAediting_674507chr9_3501629_-intronic
CAediting_674508chr9_3501633_-intronic
CAediting_674509chr9_3501653_-intronic
CAediting_674510chr9_3501654_-intronic
CAediting_674511chr9_3501662_-intronic
CAediting_674512chr9_3501689_-intronic
CAediting_674513chr9_3501694_-intronic
CAediting_674514chr9_3501695_-intronic
CAediting_674515chr9_3501722_-intronic
CAediting_674516chr9_3501727_-intronic
CAediting_674517chr9_3501751_-intronic
CAediting_674518chr9_3501752_-intronic
CAediting_674519chr9_3501760_-intronic
CAediting_674520chr9_3501761_-intronic
CAediting_674521chr9_3501770_-intronic
CAediting_674522chr9_3501775_-intronic
CAediting_674523chr9_3501788_-intronic
CAediting_674524chr9_3501789_-intronic
CAediting_674525chr9_3501813_-intronic
CAediting_674526chr9_3501821_-intronic
CAediting_674527chr9_3501829_-intronic
CAediting_674528chr9_3501830_-intronic
CAediting_674529chr9_3501836_-intronic
CAediting_674530chr9_3501838_-intronic
CAediting_674531chr9_3501848_-intronic
CAediting_674532chr9_3501865_-intronic
CAediting_674533chr9_3501866_-intronic
CAediting_674534chr9_3501867_-intronic
CAediting_674535chr9_3501995_-intronic
CAediting_674536chr9_3502058_-intronic
CAediting_674537chr9_3502062_-intronic
CAediting_674538chr9_3502137_-intronic
CAediting_674539chr9_3502196_-intronic
CAediting_674540chr9_3502252_-intronic
CAediting_674541chr9_3519994_-intronic
CAediting_674542chr9_3520048_-intronic
CAediting_674543chr9_3520058_-intronic
CAediting_674544chr9_3520064_-intronic
CAediting_674545chr9_3520072_-intronic
CAediting_674546chr9_3520104_-intronic
CAediting_674547chr9_3520106_-intronic
CAediting_674548chr9_3520107_-intronic
CAediting_674549chr9_3520705_-intronic
CAediting_674550chr9_3520754_-intronic
CAediting_674551chr9_3520765_-intronic
CAediting_674552chr9_3520803_-intronic
CAediting_674553chr9_3520807_-intronic
CAediting_674554chr9_3520813_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_674431chr9_3238869_-SINEAluAluSp
CAediting_674432chr9_3244107_-SINEAluAluSx
CAediting_674433chr9_3244167_-SINEAluAluSx
CAediting_674434chr9_3244185_-SINEAluAluSx
CAediting_674435chr9_3244209_-SINEAluAluSx
CAediting_674436chr9_3244210_-SINEAluAluSx
CAediting_674437chr9_3244214_-SINEAluAluSx
CAediting_674438chr9_3326554_-LINEL1L1PA12
CAediting_674439chr9_3326606_-LINEL1L1PA12
CAediting_674440chr9_3326712_-LINEL1L1PA12
CAediting_674441chr9_3364155_-SINEAluAluSc8
CAediting_674443chr9_3372779_-SINEAluAluSx1
CAediting_674444chr9_3372782_-SINEAluAluSx1
CAediting_674445chr9_3378677_-SINEAluAluSq2
CAediting_674446chr9_3424084_-SINEAluAluY
CAediting_674447chr9_3424121_-SINEAluAluY
CAediting_674448chr9_3424537_-SINEAluAluY
CAediting_674449chr9_3424539_-SINEAluAluY
CAediting_674450chr9_3424556_-SINEAluAluY
CAediting_674451chr9_3424565_-SINEAluAluY
CAediting_674452chr9_3424566_-SINEAluAluY
CAediting_674453chr9_3424627_-SINEAluAluY
CAediting_674454chr9_3424632_-SINEAluAluY
CAediting_674455chr9_3425012_-SINEAluAluJb
CAediting_674456chr9_3425038_-SINEAluAluJb
CAediting_674457chr9_3425057_-SINEAluAluJb
CAediting_674458chr9_3425224_-SINEAluAluJb
CAediting_674459chr9_3426704_-DNAhAT-CharlieMER1A
CAediting_674460chr9_3448657_-SINEAluAluJr
CAediting_674461chr9_3448679_-SINEAluAluJr
CAediting_674462chr9_3448702_-SINEAluAluJr
CAediting_674463chr9_3448719_-SINEAluAluJr
CAediting_674464chr9_3448792_-SINEAluAluJr
CAediting_674465chr9_3448799_-SINEAluAluJr
CAediting_674466chr9_3449597_-SINEAluAluJo
CAediting_674467chr9_3449602_-SINEAluAluJo
CAediting_674468chr9_3449725_-SINEAluAluJo
CAediting_674469chr9_3449769_-SINEAluAluJo
CAediting_674470chr9_3449830_-SINEAluAluJo
CAediting_674471chr9_3449842_-SINEAluAluJo
CAediting_674472chr9_3452334_-SINEAluAluJr
CAediting_674473chr9_3452507_-SINEAluAluJr
CAediting_674474chr9_3452549_-SINEAluAluJr
CAediting_674475chr9_3465423_-SINEAluAluSx
CAediting_674476chr9_3465428_-SINEAluAluSx
CAediting_674477chr9_3465429_-SINEAluAluSx
CAediting_674478chr9_3465523_-SINEAluAluSx
CAediting_674479chr9_3470367_-SINEAluAluY
CAediting_674480chr9_3470382_-SINEAluAluY
CAediting_674481chr9_3470383_-SINEAluAluY
CAediting_674482chr9_3470387_-SINEAluAluY
CAediting_674483chr9_3470404_-SINEAluAluY
CAediting_674484chr9_3470411_-SINEAluAluY
CAediting_674485chr9_3470412_-SINEAluAluY
CAediting_674486chr9_3470423_-SINEAluAluY
CAediting_674487chr9_3470430_-SINEAluAluY
CAediting_674488chr9_3470459_-SINEAluAluY
CAediting_674489chr9_3470479_-SINEAluAluY
CAediting_674490chr9_3470530_-SINEAluAluY
CAediting_674491chr9_3470532_-SINEAluAluY
CAediting_674492chr9_3470533_-SINEAluAluY
CAediting_674493chr9_3470556_-SINEAluAluY
CAediting_674494chr9_3470583_-SINEAluAluY
CAediting_674495chr9_3470599_-SINEAluAluY
CAediting_674496chr9_3470600_-SINEAluAluY
CAediting_674497chr9_3474840_-SINEAluAluJr
CAediting_674498chr9_3474983_-SINEAluAluJr
CAediting_674499chr9_3484983_-SINEAluAluJr
CAediting_674500chr9_3487079_-SINEAluFLAM_C
CAediting_674501chr9_3487083_-SINEAluFLAM_C
CAediting_674502chr9_3487106_-SINEAluFLAM_C
CAediting_674503chr9_3487129_-SINEAluFLAM_C
CAediting_674504chr9_3501579_-SINEAluAluSz6
CAediting_674505chr9_3501617_-SINEAluAluSz6
CAediting_674506chr9_3501622_-SINEAluAluSz6
CAediting_674507chr9_3501629_-SINEAluAluSz6
CAediting_674508chr9_3501633_-SINEAluAluSz6
CAediting_674509chr9_3501653_-SINEAluAluSz6
CAediting_674510chr9_3501654_-SINEAluAluSz6
CAediting_674511chr9_3501662_-SINEAluAluSz6
CAediting_674512chr9_3501689_-SINEAluAluSz6
CAediting_674513chr9_3501694_-SINEAluAluSz6
CAediting_674514chr9_3501695_-SINEAluAluSz6
CAediting_674515chr9_3501722_-SINEAluAluSz6
CAediting_674516chr9_3501727_-SINEAluAluSz6
CAediting_674517chr9_3501751_-SINEAluAluSz6
CAediting_674518chr9_3501752_-SINEAluAluSz6
CAediting_674519chr9_3501760_-SINEAluAluSz6
CAediting_674520chr9_3501761_-SINEAluAluSz6
CAediting_674521chr9_3501770_-SINEAluAluSz6
CAediting_674522chr9_3501775_-SINEAluAluSz6
CAediting_674523chr9_3501788_-SINEAluAluSz6
CAediting_674524chr9_3501789_-SINEAluAluSz6
CAediting_674525chr9_3501813_-SINEAluAluSz6
CAediting_674526chr9_3501821_-SINEAluAluSz6
CAediting_674527chr9_3501829_-SINEAluAluSz6
CAediting_674528chr9_3501830_-SINEAluAluSz6
CAediting_674529chr9_3501836_-SINEAluAluSz6
CAediting_674530chr9_3501838_-SINEAluAluSz6
CAediting_674531chr9_3501848_-SINEAluAluSz6
CAediting_674535chr9_3501995_-SINEAluAluY
CAediting_674536chr9_3502058_-SINEAluAluY
CAediting_674537chr9_3502062_-SINEAluAluY
CAediting_674538chr9_3502137_-SINEAluAluY
CAediting_674539chr9_3502196_-SINEAluAluY
CAediting_674540chr9_3502252_-SINEAluAluY
CAediting_674541chr9_3519994_-SINEAluAluJo
CAediting_674542chr9_3520048_-SINEAluAluJo
CAediting_674543chr9_3520058_-SINEAluAluJo
CAediting_674544chr9_3520064_-SINEAluAluJo
CAediting_674545chr9_3520072_-SINEAluAluJo
CAediting_674546chr9_3520104_-SINEAluAluJo
CAediting_674547chr9_3520106_-SINEAluAluJo
CAediting_674548chr9_3520107_-SINEAluAluJo
CAediting_674549chr9_3520705_-SINEAluAluJr
CAediting_674550chr9_3520754_-SINEAluAluJr
CAediting_674551chr9_3520765_-SINEAluAluJr
CAediting_674552chr9_3520803_-SINEAluAluJr
CAediting_674553chr9_3520807_-SINEAluAluJr
CAediting_674554chr9_3520813_-SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for RFX3

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000080298.14.RFX3.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000080298.14.RFX3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RFX3

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for RFX3

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for RFX3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000080298.14ENST00000382004hsa-miR-624-3p322500132250077mer-m832250003225020144-12.42
CAediting_393chr1_1167164_+ENSG00000080298.14ENST00000382004hsa-miR-200b-3p322142232214287mer-m832214213221442164-17.14
CAediting_980496chr14_31014685_-ENSG00000080298.14ENST00000617270hsa-miR-624-3p322500132250077mer-m832250003225020144-12.42
CAediting_393chr1_1167164_+ENSG00000080298.14ENST00000617270hsa-miR-200b-3p322142232214287mer-m832214213221442164-17.14
CAediting_1160181chr17_7017644_-ENSG00000080298.14ENST00000382004hsa-miR-195-3p322431932243268mer-1a32243193224339146-11.45
CAediting_77128chr1_85133844_+ENSG00000080298.14ENST00000382004hsa-miR-4423-3p322336432233707mer-m832233633223384141-18.41
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000382004hsa-miR-561-3p322023032202356mer32202293220251146-14.46
CAediting_1160181chr17_7017644_-ENSG00000080298.14ENST00000617270hsa-miR-195-3p322431932243268mer-1a32243193224339146-11.45
CAediting_77128chr1_85133844_+ENSG00000080298.14ENST00000617270hsa-miR-4423-3p322336432233707mer-m832233633223384141-18.41
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000617270hsa-miR-561-3p322023032202356mer32202293220251146-14.46
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000358730hsa-miR-561-3p324726432472707mer-m832472633247284171-19.93
CAediting_442554chr5_154685830_+ENSG00000080298.14ENST00000358730hsa-miR-1303324763432476407mer-m832476333247654157-23.87
CAediting_442554chr5_154685830_+ENSG00000080298.14ENST00000449234hsa-miR-1303324763432476407mer-m832476333247654157-23.87
CAediting_1229415chr17_67471547_+ENSG00000080298.14ENST00000381984hsa-miR-548aa334475233447587mer-m833447513344773154-11.57

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_573000chr7_92204081_-ENSG00000080298.14ENST00000382004hsa-miR-1285-5p321873732187448mer-1a32187373218757140-9.76
CAediting_573001chr7_92204086_-ENSG00000080298.14ENST00000382004hsa-miR-1285-5p321873732187448mer-1a32187373218757140-9.76
CAediting_442554chr5_154685830_+ENSG00000080298.14ENST00000382004hsa-miR-1303322002932200368mer-1a32200293220050140-12.55
CAediting_1160181chr17_7017644_-ENSG00000080298.14ENST00000382004hsa-miR-195-3p322499332249986mer32249923225013140-12.38
CAediting_1160181chr17_7017644_-ENSG00000080298.14ENST00000382004hsa-miR-195-3p322018332201897mer-m832201823220203148-9.1
CAediting_1229413chr17_67471544_+ENSG00000080298.14ENST00000382004hsa-miR-548aa322145732214648mer-1a32214573221489153-13.34
CAediting_1229414chr17_67471546_+ENSG00000080298.14ENST00000382004hsa-miR-548aa322145732214648mer-1a32214573221489153-13.34
CAediting_1229415chr17_67471547_+ENSG00000080298.14ENST00000382004hsa-miR-548aa322145732214648mer-1a32214573221489153-13.34
CAediting_1229413chr17_67471544_+ENSG00000080298.14ENST00000382004hsa-miR-548aa321864632186527mer-m832186453218672147-10.73
CAediting_1229414chr17_67471546_+ENSG00000080298.14ENST00000382004hsa-miR-548aa321864632186527mer-m832186453218672147-10.73
CAediting_1229415chr17_67471547_+ENSG00000080298.14ENST00000382004hsa-miR-548aa321864632186527mer-m832186453218672147-10.73
CAediting_117844chr1_162342605_+ENSG00000080298.14ENST00000382004hsa-miR-556-3p322244632224538mer-1a32224463222467145-7.99
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000382004hsa-miR-561-3p322013432201418mer-1a32201343220155155-4.48
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000382004hsa-miR-561-3p321918232191887mer-1a32191823219205150-9.88
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000382004hsa-miR-561-3p321907432190818mer-1a32190743219097143-8.61
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000382004hsa-miR-561-3p321902332190297mer-m832190223219042152-10.11
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000382004hsa-miR-561-3p321869132186977mer-m832186903218711145-8.29
CAediting_980496chr14_31014685_-ENSG00000080298.14ENST00000382004hsa-miR-624-3p322076732207737mer-1a32207673220786148-14.13
CAediting_573000chr7_92204081_-ENSG00000080298.14ENST00000617270hsa-miR-1285-5p321873732187448mer-1a32187373218757140-9.76
CAediting_573001chr7_92204086_-ENSG00000080298.14ENST00000617270hsa-miR-1285-5p321873732187448mer-1a32187373218757140-9.76
CAediting_442554chr5_154685830_+ENSG00000080298.14ENST00000617270hsa-miR-1303322002932200368mer-1a32200293220050140-12.55
CAediting_1160181chr17_7017644_-ENSG00000080298.14ENST00000617270hsa-miR-195-3p322499332249986mer32249923225013140-12.38
CAediting_1160181chr17_7017644_-ENSG00000080298.14ENST00000617270hsa-miR-195-3p322018332201897mer-m832201823220203148-9.1
CAediting_1229413chr17_67471544_+ENSG00000080298.14ENST00000617270hsa-miR-548aa322145732214648mer-1a32214573221489153-13.34
CAediting_1229414chr17_67471546_+ENSG00000080298.14ENST00000617270hsa-miR-548aa322145732214648mer-1a32214573221489153-13.34
CAediting_1229415chr17_67471547_+ENSG00000080298.14ENST00000617270hsa-miR-548aa322145732214648mer-1a32214573221489153-13.34
CAediting_1229413chr17_67471544_+ENSG00000080298.14ENST00000617270hsa-miR-548aa321864632186527mer-m832186453218672147-10.73
CAediting_1229414chr17_67471546_+ENSG00000080298.14ENST00000617270hsa-miR-548aa321864632186527mer-m832186453218672147-10.73
CAediting_1229415chr17_67471547_+ENSG00000080298.14ENST00000617270hsa-miR-548aa321864632186527mer-m832186453218672147-10.73
CAediting_117844chr1_162342605_+ENSG00000080298.14ENST00000617270hsa-miR-556-3p322244632224538mer-1a32224463222467145-7.99
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000617270hsa-miR-561-3p322013432201418mer-1a32201343220155155-4.48
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000617270hsa-miR-561-3p321918232191887mer-1a32191823219205150-9.88
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000617270hsa-miR-561-3p321907432190818mer-1a32190743219097143-8.61
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000617270hsa-miR-561-3p321902332190297mer-m832190223219042152-10.11
CAediting_228905chr2_188297554_+ENSG00000080298.14ENST00000617270hsa-miR-561-3p321869132186977mer-m832186903218711145-8.29
CAediting_980496chr14_31014685_-ENSG00000080298.14ENST00000617270hsa-miR-624-3p322076732207737mer-1a32207673220786148-14.13

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RFX3

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for RFX3

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for RFX3

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
ESCAclinical_stageCAediting_674510chr9_3501654_-0.035734038424259-0.384841086800395
ESCApathologic_stageCAediting_674507chr9_3501629_-0.004478710240790190.301948544721033
ESCApathologic_stageCAediting_674509chr9_3501653_-0.007513914232417770.272653541224934
ESCApathologic_stageCAediting_674510chr9_3501654_-4.26242243375908e-050.413125729710495
OVclinical_stageCAediting_674510chr9_3501654_-0.0373171344758612-0.216284487771408

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Relation with survival for RFX3

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
OVCAediting_674507chr9_3501629_-0.002560174711297660.006714140.0731285

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RelatedDrugs for RFX3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RFX3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
RFX3C0037274Dermatologic disorders1CTD_human
RFX3C0274861Arsenic Poisoning, Inorganic1CTD_human
RFX3C0274862Nervous System, Organic Arsenic Poisoning1CTD_human
RFX3C0311375Arsenic Poisoning1CTD_human
RFX3C0751851Arsenic Encephalopathy1CTD_human
RFX3C0751852Arsenic Induced Polyneuropathy1CTD_human