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Editing gene: RBM3 (CAeditome ID:5935)

Gene summary for RBM3

Gene summary

Gene information	Gene symbol	RBM3
	Gene ID	5935
	Gene name	RNA binding motif protein 3
	Synonyms	IS1-RNPL\|RNPL
	Cytomap	Xp11.23
	Type of gene	protein-coding
	Description	RNA-binding protein 3RNA binding motif (RNP1, RRM) protein 3
	Modification date	20210518
	UniProtAcc	P98179
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
RBM3	GO:0005654	RNA-binding protein 3	0000052

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RNA A-to-I events for RBM3

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000102317.16

RNA A-to-I editing events in Cancer.

CAediting_1506663(48577881, +), CAediting_1506664(48577934, +), CAediting_1506665(48577960, +), CAediting_1506666(48577961, +), CAediting_1506667(48577992, +), CAediting_1506668(48578031, +), CAediting_1506669(48578338, +), CAediting_1506670(48578340, +), CAediting_1506671(48578350, +), CAediting_1506672(48578353, +), CAediting_1506673(48578358, +), CAediting_1506674(48578363, +), CAediting_1506675(48578372, +), CAediting_1506676(48578374, +), CAediting_1506677(48578377, +), CAediting_1506678(48578386, +), CAediting_1506679(48578387, +), CAediting_1506680(48578394, +), CAediting_1506681(48578395, +), CAediting_1506682(48578397, +), CAediting_1506683(48578402, +), CAediting_1506684(48578411, +), CAediting_1506685(48578415, +), CAediting_1506686(48578417, +), CAediting_1506687(48578419, +), CAediting_1506688(48578421, +), CAediting_1506689(48578422, +), CAediting_1506690(48578426, +), CAediting_1506691(48578452, +), CAediting_1506692(48578453, +), CAediting_1506693(48578458, +), CAediting_1506694(48578462, +), CAediting_1506695(48578469, +), CAediting_1506696(48578475, +), CAediting_1506697(48578479, +), CAediting_1506698(48578482, +), CAediting_1506699(48578484, +), CAediting_1506700(48578485, +), CAediting_1506701(48578493, +), CAediting_1506702(48578494, +), CAediting_1506703(48578498, +), CAediting_1506704(48578501, +), CAediting_1506705(48578508, +), CAediting_1506706(48578518, +), CAediting_1506707(48578523, +), CAediting_1506708(48578525, +), CAediting_1506709(48578533, +), CAediting_1506710(48578548, +), CAediting_1506711(48578558, +), CAediting_1506712(48578762, +),

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RNA editing positional annotations for RBM3 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1506663	chrX_48577881_+	ncRNA_exonic
CAediting_1506664	chrX_48577934_+	ncRNA_exonic
CAediting_1506665	chrX_48577960_+	ncRNA_exonic
CAediting_1506666	chrX_48577961_+	ncRNA_exonic
CAediting_1506667	chrX_48577992_+	UTR3
CAediting_1506668	chrX_48578031_+	UTR3
CAediting_1506669	chrX_48578338_+	UTR3
CAediting_1506670	chrX_48578340_+	UTR3
CAediting_1506671	chrX_48578350_+	UTR3
CAediting_1506672	chrX_48578353_+	UTR3
CAediting_1506673	chrX_48578358_+	UTR3
CAediting_1506674	chrX_48578363_+	UTR3
CAediting_1506675	chrX_48578372_+	UTR3
CAediting_1506676	chrX_48578374_+	UTR3
CAediting_1506677	chrX_48578377_+	UTR3
CAediting_1506678	chrX_48578386_+	UTR3
CAediting_1506679	chrX_48578387_+	UTR3
CAediting_1506680	chrX_48578394_+	UTR3
CAediting_1506681	chrX_48578395_+	UTR3
CAediting_1506682	chrX_48578397_+	UTR3
CAediting_1506683	chrX_48578402_+	UTR3
CAediting_1506684	chrX_48578411_+	UTR3
CAediting_1506685	chrX_48578415_+	UTR3
CAediting_1506686	chrX_48578417_+	UTR3
CAediting_1506687	chrX_48578419_+	UTR3
CAediting_1506688	chrX_48578421_+	UTR3
CAediting_1506689	chrX_48578422_+	UTR3
CAediting_1506690	chrX_48578426_+	UTR3
CAediting_1506691	chrX_48578452_+	UTR3
CAediting_1506692	chrX_48578453_+	UTR3
CAediting_1506693	chrX_48578458_+	UTR3
CAediting_1506694	chrX_48578462_+	UTR3
CAediting_1506695	chrX_48578469_+	UTR3
CAediting_1506696	chrX_48578475_+	UTR3
CAediting_1506697	chrX_48578479_+	UTR3
CAediting_1506698	chrX_48578482_+	UTR3
CAediting_1506699	chrX_48578484_+	UTR3
CAediting_1506700	chrX_48578485_+	UTR3
CAediting_1506701	chrX_48578493_+	UTR3
CAediting_1506702	chrX_48578494_+	UTR3
CAediting_1506703	chrX_48578498_+	UTR3
CAediting_1506704	chrX_48578501_+	UTR3
CAediting_1506705	chrX_48578508_+	UTR3
CAediting_1506706	chrX_48578518_+	UTR3
CAediting_1506707	chrX_48578523_+	UTR3
CAediting_1506708	chrX_48578525_+	UTR3
CAediting_1506709	chrX_48578533_+	UTR3
CAediting_1506710	chrX_48578548_+	UTR3
CAediting_1506711	chrX_48578558_+	UTR3
CAediting_1506712	chrX_48578762_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1506664	chrX_48577934_+	SINE	Alu	AluSx
CAediting_1506665	chrX_48577960_+	SINE	Alu	AluSx
CAediting_1506666	chrX_48577961_+	SINE	Alu	AluSx
CAediting_1506667	chrX_48577992_+	SINE	Alu	AluSx
CAediting_1506668	chrX_48578031_+	SINE	Alu	AluSx
CAediting_1506669	chrX_48578338_+	SINE	Alu	AluSx1
CAediting_1506670	chrX_48578340_+	SINE	Alu	AluSx1
CAediting_1506671	chrX_48578350_+	SINE	Alu	AluSx1
CAediting_1506672	chrX_48578353_+	SINE	Alu	AluSx1
CAediting_1506673	chrX_48578358_+	SINE	Alu	AluSx1
CAediting_1506674	chrX_48578363_+	SINE	Alu	AluSx1
CAediting_1506675	chrX_48578372_+	SINE	Alu	AluSx1
CAediting_1506676	chrX_48578374_+	SINE	Alu	AluSx1
CAediting_1506677	chrX_48578377_+	SINE	Alu	AluSx1
CAediting_1506678	chrX_48578386_+	SINE	Alu	AluSx1
CAediting_1506679	chrX_48578387_+	SINE	Alu	AluSx1
CAediting_1506680	chrX_48578394_+	SINE	Alu	AluSx1
CAediting_1506681	chrX_48578395_+	SINE	Alu	AluSx1
CAediting_1506682	chrX_48578397_+	SINE	Alu	AluSx1
CAediting_1506683	chrX_48578402_+	SINE	Alu	AluSx1
CAediting_1506684	chrX_48578411_+	SINE	Alu	AluSx1
CAediting_1506685	chrX_48578415_+	SINE	Alu	AluSx1
CAediting_1506686	chrX_48578417_+	SINE	Alu	AluSx1
CAediting_1506687	chrX_48578419_+	SINE	Alu	AluSx1
CAediting_1506688	chrX_48578421_+	SINE	Alu	AluSx1
CAediting_1506689	chrX_48578422_+	SINE	Alu	AluSx1
CAediting_1506690	chrX_48578426_+	SINE	Alu	AluSx1
CAediting_1506691	chrX_48578452_+	SINE	Alu	AluSx1
CAediting_1506692	chrX_48578453_+	SINE	Alu	AluSx1
CAediting_1506693	chrX_48578458_+	SINE	Alu	AluSx1
CAediting_1506694	chrX_48578462_+	SINE	Alu	AluSx1
CAediting_1506695	chrX_48578469_+	SINE	Alu	AluSx1
CAediting_1506696	chrX_48578475_+	SINE	Alu	AluSx1
CAediting_1506697	chrX_48578479_+	SINE	Alu	AluSx1
CAediting_1506698	chrX_48578482_+	SINE	Alu	AluSx1
CAediting_1506699	chrX_48578484_+	SINE	Alu	AluSx1
CAediting_1506700	chrX_48578485_+	SINE	Alu	AluSx1
CAediting_1506701	chrX_48578493_+	SINE	Alu	AluSx1
CAediting_1506702	chrX_48578494_+	SINE	Alu	AluSx1
CAediting_1506703	chrX_48578498_+	SINE	Alu	AluSx1
CAediting_1506704	chrX_48578501_+	SINE	Alu	AluSx1
CAediting_1506705	chrX_48578508_+	SINE	Alu	AluSx1
CAediting_1506706	chrX_48578518_+	SINE	Alu	AluSx1
CAediting_1506707	chrX_48578523_+	SINE	Alu	AluSx1
CAediting_1506708	chrX_48578525_+	SINE	Alu	AluSx1
CAediting_1506709	chrX_48578533_+	SINE	Alu	AluSx1
CAediting_1506710	chrX_48578548_+	SINE	Alu	AluSx1
CAediting_1506711	chrX_48578558_+	SINE	Alu	AluSx1

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RNA A-to-I editing events in the alternative splicing sites for RBM3

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000102317.16.RBM3.

Correlation between RNA A-to-I editing and PSI for ENSG00000102317.16.RBM3.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RBM3

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

HNSC.CAediting_1506688.ENSG00000102317.RBM3.png
Soverview

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Protein coding region RNA A-to-I editings for RBM3

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for RBM3

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1506663	chrX_48577881_+	ENSG00000102317.16	ENST00000354480	hsa-miR-3176	48577879	48577885	7mer-m8	48577868	48577886	146.00	-19.92
CAediting_1506663	chrX_48577881_+	ENSG00000102317.16	ENST00000354480	hsa-miR-3922-3p	48577879	48577885	7mer-m8	48577862	48577886	144.00	-15.67
CAediting_1506664	chrX_48577934_+	ENSG00000102317.16	ENST00000354480	hsa-miR-1972	48577932	48577938	7mer-m8	48577918	48577939	141.00	-17.57
CAediting_1506664	chrX_48577934_+	ENSG00000102317.16	ENST00000354480	hsa-miR-1972	48577932	48577938	7mer-m8	48577918	48577939	141.00	-17.57
CAediting_1506665	chrX_48577960_+	ENSG00000102317.16	ENST00000354480	hsa-miR-513a-5p	48577954	48577960	7mer-m8	48577944	48577961	140.00	-15.01
CAediting_1506665	chrX_48577960_+	ENSG00000102317.16	ENST00000354480	hsa-miR-513a-5p	48577954	48577960	7mer-m8	48577944	48577961	140.00	-15.01
CAediting_1506665	chrX_48577960_+	ENSG00000102317.16	ENST00000354480	hsa-miR-638	48577959	48577965	7mer-1a	48577941	48577965	155.00	-32.71
CAediting_1506668	chrX_48578031_+	ENSG00000102317.16	ENST00000354480	hsa-miR-7975	48578027	48578032	6mer	48578015	48578033	142.00	-21.10

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1506665	chrX_48577960_+	ENSG00000102317.16	ENST00000354480	hsa-miR-10399-5p	48577955	48577961	7mer-m8	48577941	48577962	144	-9.33
CAediting_1506666	chrX_48577961_+	ENSG00000102317.16	ENST00000354480	hsa-miR-10399-5p	48577955	48577961	7mer-m8	48577941	48577962	144	-9.33
CAediting_1506664	chrX_48577934_+	ENSG00000102317.16	ENST00000354480	hsa-miR-4735-5p	48577928	48577934	7mer-m8	48577914	48577935	140	-5.5
CAediting_1506666	chrX_48577961_+	ENSG00000102317.16	ENST00000354480	hsa-miR-5089-5p	48577959	48577965	7mer-m8	48577946	48577966	148	-15.11
CAediting_1506665	chrX_48577960_+	ENSG00000102317.16	ENST00000354480	hsa-miR-6504-3p	48577955	48577961	7mer-m8	48577938	48577962	148	-14.06
CAediting_1506666	chrX_48577961_+	ENSG00000102317.16	ENST00000354480	hsa-miR-6504-3p	48577955	48577961	7mer-m8	48577938	48577962	148	-14.06
CAediting_1506665	chrX_48577960_+	ENSG00000102317.16	ENST00000354480	hsa-miR-7151-3p	48577953	48577960	8mer-1a	48577940	48577960	140	-11.52

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000102317.16	ENST00000354480	hsa-miR-605-3p	48577202	48577209	8mer-1a	48577189	48577209	158	-20.89
CAediting_846604	chr11_93733708_-	ENSG00000102317.16	ENST00000354480	hsa-miR-1304-3p	48578061	48578068	8mer-1a	48578047	48578068	160	-23.31
CAediting_1229415	chr17_67471547_+	ENSG00000102317.16	ENST00000354480	hsa-miR-548aa	48578163	48578170	8mer-1a	48578149	48578170	153	-12.84
CAediting_524911	chr7_5495852_-	ENSG00000102317.16	ENST00000354480	hsa-miR-589-3p	48577186	48577192	7mer-m8	48577168	48577193	147	-20.31
CAediting_1524209	chrX_134546392_-	ENSG00000102317.16	ENST00000354480	hsa-miR-503-5p	48577200	48577205	6mer	48577182	48577206	143	-26.65

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1351755	chr19_40282625_-	ENSG00000102317.16	ENST00000354480	hsa-miR-641	48578183	48578189	7mer-m8	48578167	48578190	142	-11.5

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RBM3

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for RBM3

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_1506676	chrX_48578374_+	0.00320681991493683	0.187954897897369	.	.	.	.
BRCA	CAediting_1506676	chrX_48578374_+	0.0155785504405353	0.12669582600432	.	.	.	.
SKCM	CAediting_1506676	chrX_48578374_+	0.00115799079428887	0.266307942871354	.	.	.	.
BRCA	CAediting_1506686	chrX_48578417_+	3.8917250014676e-10	0.285246451007656	.	.	.	.
LUAD	CAediting_1506686	chrX_48578417_+	0.04834668037077	0.19998166780867	.	.	.	.
LUSC	CAediting_1506686	chrX_48578417_+	0.0246786537540067	0.234138592903764	.	.	.	.
HNSC	CAediting_1506686	chrX_48578417_+	8.13985881782626e-05	0.380079904111619	.	.	.	.
STAD	CAediting_1506686	chrX_48578417_+	0.0252113404268482	0.198584742678084	.	.	.	.
SKCM	CAediting_1506686	chrX_48578417_+	0.000378495263980216	0.288401411206915	.	.	.	.
SARC	CAediting_1506686	chrX_48578417_+	0.00129549422724959	0.3578838956826	.	.	.	.
BRCA	CAediting_1506688	chrX_48578421_+	0.000188506332404508	0.2993530405438	0.037190224368731	0.169744634110087	.	.
BLCA	CAediting_1506689	chrX_48578422_+	0.00491620596978664	0.334865231421517	.	.	.	.
BRCA	CAediting_1506689	chrX_48578422_+	4.69536765544819e-10	0.249136535702078	.	.	.	.
CESC	CAediting_1506689	chrX_48578422_+	0.00611964899739261	0.344432922887017	.	.	.	.
LUAD	CAediting_1506689	chrX_48578422_+	0.0101935820694352	0.212027169563126	.	.	.	.
HNSC	CAediting_1506689	chrX_48578422_+	0.00617335998814533	0.210473772729676	.	.	.	.
STAD	CAediting_1506689	chrX_48578422_+	0.00609924242429518	0.212027904803643	.	.	.	.
THCA	CAediting_1506689	chrX_48578422_+	0.0277845969996531	0.139179614184539	.	.	.	.
SKCM	CAediting_1506689	chrX_48578422_+	2.34650987910877e-05	0.284111091012946	.	.	.	.
SARC	CAediting_1506689	chrX_48578422_+	0.00120272161862389	0.32087866795537	.	.	.	.
BLCA	CAediting_1506690	chrX_48578426_+	.	.	.	.	7.78329939872602e-05	0.502998992842074
BRCA	CAediting_1506690	chrX_48578426_+	2.56725518941187e-05	0.181723472771013	.	.	.	.
CESC	CAediting_1506690	chrX_48578426_+	0.00326575711059521	0.408045671517172	.	.	.	.
LUSC	CAediting_1506690	chrX_48578426_+	0.01126256883911	0.243036867671273	.	.	.	.
BLCA	CAediting_1506691	chrX_48578452_+	0.00881077667840382	0.256877225761016	.	.	.	.
LGG	CAediting_1506691	chrX_48578452_+	0.000347590537978114	0.191214131556955	.	.	.	.
BRCA	CAediting_1506691	chrX_48578452_+	9.4827936436414e-21	0.349337772378212	.	.	.	.
CESC	CAediting_1506691	chrX_48578452_+	0.00396505933624536	0.320635902976005	.	.	0.0434988396803146	0.227778013911467
LUAD	CAediting_1506691	chrX_48578452_+	1.61187504456516e-06	0.326213194564959	.	.	.	.
COAD	CAediting_1506691	chrX_48578452_+	0.000493966607589319	0.335721095675756	.	.	.	.
LUSC	CAediting_1506691	chrX_48578452_+	0.017483507647208	0.170028170216466	.	.	.	.
HNSC	CAediting_1506691	chrX_48578452_+	7.26088820226357e-08	0.349532713731854	.	.	.	.
THCA	CAediting_1506691	chrX_48578452_+	1.40543623705765e-05	0.24665345279271	.	.	.	.
KIRC	CAediting_1506691	chrX_48578452_+	0.000358371754047505	0.197693927900255	.	.	.	.
PAAD	CAediting_1506691	chrX_48578452_+	0.0117820544041165	0.293327972507282	.	.	.	.
SKCM	CAediting_1506691	chrX_48578452_+	0.000177999293831685	0.23264515711829	.	.	.	.
SARC	CAediting_1506691	chrX_48578452_+	3.17337885786604e-07	0.44491352627817	.	.	.	.
BLCA	CAediting_1506692	chrX_48578453_+	0.00988840530677837	0.242823747524534	0.0196225422980084	0.220249833421257	.	.
BRCA	CAediting_1506692	chrX_48578453_+	4.65936842552491e-19	0.328565200716805	.	.	.	.
CESC	CAediting_1506692	chrX_48578453_+	0.00895627831418619	0.277106496865221	.	.	.	.
LUAD	CAediting_1506692	chrX_48578453_+	7.19520804120073e-07	0.328927525896472	.	.	.	.
COAD	CAediting_1506692	chrX_48578453_+	0.0196447760225043	0.211881997917186	.	.	.	.
HNSC	CAediting_1506692	chrX_48578453_+	6.35080833151436e-09	0.365987396677877	0.00389415908756563	0.186839373659471	.	.
THCA	CAediting_1506692	chrX_48578453_+	7.89159994663947e-08	0.293312270150834	.	.	.	.
KIRP	CAediting_1506692	chrX_48578453_+	.	.	0.0446534505644299	0.214610960447104	.	.
PAAD	CAediting_1506692	chrX_48578453_+	0.00320826647064968	0.325585856613267	.	.	.	.
SKCM	CAediting_1506692	chrX_48578453_+	0.00141059413177517	0.194782288347875	.	.	.	.
SARC	CAediting_1506692	chrX_48578453_+	0.000407174342825248	0.31144151979188	.	.	.	.
TGCT	CAediting_1506692	chrX_48578453_+	0.0403322509612431	0.291012191116294	.	.	.	.
BRCA	CAediting_1506693	chrX_48578458_+	0.0116363932965887	0.172588353393674	.	.	.	.
BRCA	CAediting_1506694	chrX_48578462_+	4.07316344409694e-06	0.219359290132402	.	.	0.0342813826887106	0.101754313131952
LUAD	CAediting_1506694	chrX_48578462_+	0.0468726158237374	0.190810127588023	.	.	.	.
HNSC	CAediting_1506694	chrX_48578462_+	0.0159692439184435	0.232476061924316	0.031452294972016	0.208135651907204	.	.
THCA	CAediting_1506694	chrX_48578462_+	0.0216813581825096	0.198220704237729	.	.	.	.
SKCM	CAediting_1506694	chrX_48578462_+	.	.	0.00222619390058233	0.240856122520273	.	.
SARC	CAediting_1506694	chrX_48578462_+	.	.	0.00278368494223694	0.367879206963158	.	.
STAD	CAediting_1506703	chrX_48578498_+	0.012804367162092	0.213738979535392	.	.	.	.
ESCA	CAediting_1506703	chrX_48578498_+	.	.	0.000533447207565298	0.356009886528007	.	.
STAD	CAediting_1506705	chrX_48578508_+	0.0411418780244422	0.174088629856642	.	.	.	.

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Relation with cancer stages for RBM3

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_1506692	chrX_48578453_+	0.0433463828594028	0.0773893738504201
CESC	clinical_stage	CAediting_1506690	chrX_48578426_+	0.0372752768256016	0.298420641190662
ESCA	clinical_stage	CAediting_1506694	chrX_48578462_+	0.0269108736814547	-0.451158578049044
OV	clinical_stage	CAediting_1506676	chrX_48578374_+	0.0328443029846344	0.174360488890375
PAAD	pathologic_stage	CAediting_1506691	chrX_48578452_+	0.0212047281595424	0.269344031179443
THCA	pathologic_stage	CAediting_1506686	chrX_48578417_+	0.0158986523991247	0.190370771092705
THCA	pathologic_stage	CAediting_1506691	chrX_48578452_+	0.0155014720042232	0.139642129717467
THCA	pathologic_stage	CAediting_1506692	chrX_48578453_+	0.0286836123315787	0.12232122825506

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Relation with survival for RBM3

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
CESC	CAediting_1506690	chrX_48578426_+	0.0470899677892619	0.0339546	85230.8
OV	CAediting_1506690	chrX_48578426_+	0.0046302591305174	0.0129519	0.0547569

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RelatedDrugs for RBM3

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for RBM3

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
RBM3	C0006142	Malignant neoplasm of breast	1	CTD_human
RBM3	C0023893	Liver Cirrhosis, Experimental	1	CTD_human
RBM3	C0678222	Breast Carcinoma	1	CTD_human
RBM3	C1257931	Mammary Neoplasms, Human	1	CTD_human
RBM3	C1458155	Mammary Neoplasms	1	CTD_human
RBM3	C4704874	Mammary Carcinoma, Human	1	CTD_human

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene