Home

Download

Statistics

Examples

Help

Contact

Editing gene: SCPEP1 (CAeditome ID:59342)

Gene summary for SCPEP1

Gene summary

Gene information	Gene symbol	SCPEP1
	Gene ID	59342
	Gene name	serine carboxypeptidase 1
	Synonyms	HSCP1\|RISC
	Cytomap	17q22
	Type of gene	protein-coding
	Description	retinoid-inducible serine carboxypeptidaseserine carboxypeptidase 1 precursor protein
	Modification date	20210522
	UniProtAcc	Q9HB40
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

Top

RNA A-to-I events for SCPEP1

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000121064.11

RNA A-to-I editing events in Cancer.

CAediting_1215470(56981679, +), CAediting_1215471(56981683, +), CAediting_1215472(56981688, +), CAediting_1215473(56981767, +), CAediting_1215474(56981804, +), CAediting_1215475(56984009, +), CAediting_1215476(56984026, +), CAediting_1215477(56984087, +), CAediting_1215478(56984090, +), CAediting_1215479(56984860, +), CAediting_1215480(56985040, +), CAediting_1215481(56985062, +), CAediting_1215482(56990887, +), CAediting_1215483(56990981, +), CAediting_1215484(56991024, +), CAediting_1215485(56996213, +), CAediting_1215486(56996279, +), CAediting_1215487(56996304, +), CAediting_1215488(56996305, +), CAediting_1215489(56996528, +), CAediting_1215490(56996570, +), CAediting_1215491(56996575, +), CAediting_1215492(56996600, +), CAediting_1215493(56996619, +), CAediting_1215494(56996620, +), CAediting_1215495(56996637, +), CAediting_1215496(56996659, +), CAediting_1215497(56996666, +), CAediting_1215498(56996700, +), CAediting_1215499(56996703, +), CAediting_1215500(56996716, +), CAediting_1215501(56996725, +), CAediting_1215502(56996793, +), CAediting_1215503(56997623, +), CAediting_1215504(56998036, +), CAediting_1215505(56998050, +), CAediting_1215506(56998058, +), CAediting_1215507(56998059, +), CAediting_1215508(56998101, +), CAediting_1215509(56998102, +), CAediting_1215510(56998115, +), CAediting_1215511(56998125, +), CAediting_1215512(56998133, +), CAediting_1215513(56998146, +), CAediting_1215514(56998149, +), CAediting_1215515(56998150, +), CAediting_1215516(56998151, +), CAediting_1215517(56998152, +), CAediting_1215518(56998153, +), CAediting_1215519(56998155, +), CAediting_1215520(56998158, +), CAediting_1215521(56998159, +), CAediting_1215522(56998160, +), CAediting_1215523(56998161, +), CAediting_1215524(56998200, +), CAediting_1215525(56998213, +), CAediting_1215526(56998217, +), CAediting_1215527(56998220, +), CAediting_1215528(56998222, +), CAediting_1215529(56998223, +), CAediting_1215530(56998231, +), CAediting_1215531(56998232, +), CAediting_1215532(56998236, +), CAediting_1215533(56998239, +),

Top

RNA editing positional annotations for SCPEP1 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_1215470	chr17_56981679_+	ncRNA_intronic
CAediting_1215471	chr17_56981683_+	ncRNA_intronic
CAediting_1215472	chr17_56981688_+	ncRNA_intronic
CAediting_1215473	chr17_56981767_+	ncRNA_intronic
CAediting_1215474	chr17_56981804_+	ncRNA_intronic
CAediting_1215475	chr17_56984009_+	ncRNA_exonic
CAediting_1215476	chr17_56984026_+	ncRNA_exonic
CAediting_1215477	chr17_56984087_+	ncRNA_exonic
CAediting_1215478	chr17_56984090_+	ncRNA_exonic
CAediting_1215479	chr17_56984860_+	ncRNA_exonic
CAediting_1215480	chr17_56985040_+	ncRNA_exonic
CAediting_1215481	chr17_56985062_+	ncRNA_exonic
CAediting_1215482	chr17_56990887_+	ncRNA_intronic
CAediting_1215483	chr17_56990981_+	ncRNA_intronic
CAediting_1215484	chr17_56991024_+	ncRNA_intronic
CAediting_1215485	chr17_56996213_+	ncRNA_intronic
CAediting_1215486	chr17_56996279_+	ncRNA_intronic
CAediting_1215487	chr17_56996304_+	ncRNA_intronic
CAediting_1215488	chr17_56996305_+	ncRNA_intronic
CAediting_1215489	chr17_56996528_+	ncRNA_intronic
CAediting_1215490	chr17_56996570_+	ncRNA_intronic
CAediting_1215491	chr17_56996575_+	ncRNA_intronic
CAediting_1215492	chr17_56996600_+	ncRNA_intronic
CAediting_1215493	chr17_56996619_+	ncRNA_intronic
CAediting_1215494	chr17_56996620_+	ncRNA_intronic
CAediting_1215495	chr17_56996637_+	ncRNA_intronic
CAediting_1215496	chr17_56996659_+	ncRNA_intronic
CAediting_1215497	chr17_56996666_+	ncRNA_intronic
CAediting_1215498	chr17_56996700_+	ncRNA_intronic
CAediting_1215499	chr17_56996703_+	ncRNA_intronic
CAediting_1215500	chr17_56996716_+	ncRNA_intronic
CAediting_1215501	chr17_56996725_+	ncRNA_intronic
CAediting_1215502	chr17_56996793_+	ncRNA_intronic
CAediting_1215503	chr17_56997623_+	ncRNA_intronic
CAediting_1215504	chr17_56998036_+	ncRNA_exonic
CAediting_1215505	chr17_56998050_+	ncRNA_exonic
CAediting_1215506	chr17_56998058_+	ncRNA_exonic
CAediting_1215507	chr17_56998059_+	ncRNA_exonic
CAediting_1215508	chr17_56998101_+	ncRNA_exonic
CAediting_1215509	chr17_56998102_+	ncRNA_exonic
CAediting_1215510	chr17_56998115_+	ncRNA_exonic
CAediting_1215511	chr17_56998125_+	ncRNA_exonic
CAediting_1215512	chr17_56998133_+	ncRNA_exonic
CAediting_1215513	chr17_56998146_+	ncRNA_exonic
CAediting_1215514	chr17_56998149_+	ncRNA_exonic
CAediting_1215515	chr17_56998150_+	ncRNA_exonic
CAediting_1215516	chr17_56998151_+	ncRNA_exonic
CAediting_1215517	chr17_56998152_+	ncRNA_exonic
CAediting_1215518	chr17_56998153_+	ncRNA_exonic
CAediting_1215519	chr17_56998155_+	ncRNA_exonic
CAediting_1215520	chr17_56998158_+	ncRNA_exonic
CAediting_1215521	chr17_56998159_+	ncRNA_exonic
CAediting_1215522	chr17_56998160_+	ncRNA_exonic
CAediting_1215523	chr17_56998161_+	ncRNA_exonic
CAediting_1215524	chr17_56998200_+	ncRNA_exonic
CAediting_1215525	chr17_56998213_+	ncRNA_exonic
CAediting_1215526	chr17_56998217_+	ncRNA_exonic
CAediting_1215527	chr17_56998220_+	ncRNA_exonic
CAediting_1215528	chr17_56998222_+	ncRNA_exonic
CAediting_1215529	chr17_56998223_+	ncRNA_exonic
CAediting_1215530	chr17_56998231_+	ncRNA_exonic
CAediting_1215531	chr17_56998232_+	ncRNA_exonic
CAediting_1215532	chr17_56998236_+	ncRNA_exonic
CAediting_1215533	chr17_56998239_+	ncRNA_exonic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_1215470	chr17_56981679_+	SINE	Alu	AluSz6
CAediting_1215471	chr17_56981683_+	SINE	Alu	AluSz6
CAediting_1215472	chr17_56981688_+	SINE	Alu	AluSz6
CAediting_1215473	chr17_56981767_+	SINE	Alu	AluSz6
CAediting_1215474	chr17_56981804_+	SINE	Alu	AluSz6
CAediting_1215475	chr17_56984009_+	SINE	Alu	AluSz
CAediting_1215476	chr17_56984026_+	SINE	Alu	AluSz
CAediting_1215477	chr17_56984087_+	SINE	Alu	AluSz
CAediting_1215478	chr17_56984090_+	SINE	Alu	AluSz
CAediting_1215479	chr17_56984860_+	SINE	Alu	AluJb
CAediting_1215480	chr17_56985040_+	SINE	Alu	AluJb
CAediting_1215481	chr17_56985062_+	SINE	Alu	AluJb
CAediting_1215482	chr17_56990887_+	SINE	Alu	AluJb
CAediting_1215483	chr17_56990981_+	SINE	Alu	AluJo
CAediting_1215484	chr17_56991024_+	SINE	Alu	AluJo
CAediting_1215485	chr17_56996213_+	Simple_repeat	Simple_repeat	(TATT)n
CAediting_1215486	chr17_56996279_+	SINE	Alu	AluSx
CAediting_1215487	chr17_56996304_+	SINE	Alu	AluSx
CAediting_1215488	chr17_56996305_+	SINE	Alu	AluSx
CAediting_1215489	chr17_56996528_+	SINE	Alu	AluSz
CAediting_1215490	chr17_56996570_+	SINE	Alu	AluSz
CAediting_1215491	chr17_56996575_+	SINE	Alu	AluSz
CAediting_1215492	chr17_56996600_+	SINE	Alu	AluSz
CAediting_1215493	chr17_56996619_+	SINE	Alu	AluSz
CAediting_1215494	chr17_56996620_+	SINE	Alu	AluSz
CAediting_1215495	chr17_56996637_+	SINE	Alu	AluSz
CAediting_1215496	chr17_56996659_+	SINE	Alu	AluSz
CAediting_1215497	chr17_56996666_+	SINE	Alu	AluSz
CAediting_1215498	chr17_56996700_+	SINE	Alu	AluSz
CAediting_1215499	chr17_56996703_+	SINE	Alu	AluSz
CAediting_1215500	chr17_56996716_+	SINE	Alu	AluSz
CAediting_1215501	chr17_56996725_+	SINE	Alu	AluSz
CAediting_1215502	chr17_56996793_+	SINE	Alu	AluSz
CAediting_1215503	chr17_56997623_+	DNA	TcMar-Mariner	MADE1
CAediting_1215504	chr17_56998036_+	SINE	Alu	AluSc
CAediting_1215505	chr17_56998050_+	SINE	Alu	AluSc
CAediting_1215506	chr17_56998058_+	SINE	Alu	AluSc
CAediting_1215507	chr17_56998059_+	SINE	Alu	AluSc
CAediting_1215508	chr17_56998101_+	SINE	Alu	AluSc
CAediting_1215509	chr17_56998102_+	SINE	Alu	AluSc
CAediting_1215510	chr17_56998115_+	SINE	Alu	AluSc
CAediting_1215511	chr17_56998125_+	SINE	Alu	AluSc
CAediting_1215512	chr17_56998133_+	SINE	Alu	AluSc
CAediting_1215513	chr17_56998146_+	SINE	Alu	AluSc
CAediting_1215514	chr17_56998149_+	SINE	Alu	AluSc
CAediting_1215515	chr17_56998150_+	SINE	Alu	AluSc
CAediting_1215516	chr17_56998151_+	SINE	Alu	AluSc
CAediting_1215517	chr17_56998152_+	SINE	Alu	AluSc
CAediting_1215518	chr17_56998153_+	SINE	Alu	AluSc
CAediting_1215519	chr17_56998155_+	SINE	Alu	AluSc
CAediting_1215520	chr17_56998158_+	SINE	Alu	AluSc
CAediting_1215521	chr17_56998159_+	SINE	Alu	AluSc
CAediting_1215522	chr17_56998160_+	SINE	Alu	AluSc
CAediting_1215523	chr17_56998161_+	SINE	Alu	AluSc
CAediting_1215524	chr17_56998200_+	SINE	Alu	AluSc
CAediting_1215525	chr17_56998213_+	SINE	Alu	AluSc
CAediting_1215526	chr17_56998217_+	SINE	Alu	AluSc
CAediting_1215527	chr17_56998220_+	SINE	Alu	AluSc
CAediting_1215528	chr17_56998222_+	SINE	Alu	AluSc
CAediting_1215529	chr17_56998223_+	SINE	Alu	AluSc
CAediting_1215530	chr17_56998231_+	SINE	Alu	AluSc
CAediting_1215531	chr17_56998232_+	SINE	Alu	AluSc
CAediting_1215532	chr17_56998236_+	SINE	Alu	AluSc
CAediting_1215533	chr17_56998239_+	SINE	Alu	AluSc

Top

RNA A-to-I editing events in the alternative splicing sites for SCPEP1

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	CAediting_1215497	chr17_56996666_+	56996660:56996668	5SS	0+4i	CAGGTGAGC	9.6	CAGGTGGGC	8.07
IR	CAediting_1215497	chr17_56996666_+	56996660:56996668	5SS	0+4i	CAGGTGAGC	9.6	CAGGTGGGC	8.07
ES	CAediting_1215512	chr17_56998133_+	56998127:56998135	5SS	0+4i	ATGGTGAAA	0.56	ATGGTGGAA	-4.72

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000121064.11.SCPEP1.

Correlation between RNA A-to-I editing and PSI for ENSG00000121064.11.SCPEP1.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for SCPEP1

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for SCPEP1

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

Top

The effects of the RNA editing to the miRNA binding sites for SCPEP1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1368054	chr19_46709310_-	ENSG00000121064.11	ENST00000575423	hsa-miR-320e	56998433	56998440	8mer-1a	56998423	56998440	158	-18.89
CAediting_573001	chr7_92204086_-	ENSG00000121064.11	ENST00000575423	hsa-miR-1285-5p	56998404	56998411	8mer-1a	56998389	56998411	150	-17.7
CAediting_1368054	chr19_46709310_-	ENSG00000121064.11	ENST00000576154	hsa-miR-320e	56998433	56998440	8mer-1a	56998423	56998440	158	-18.89
CAediting_573001	chr7_92204086_-	ENSG00000121064.11	ENST00000576154	hsa-miR-1285-5p	56998404	56998411	8mer-1a	56998389	56998411	150	-17.7

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for SCPEP1

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

Top

Relation with ADAR for SCPEP1

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

Top

Relation with cancer stages for SCPEP1

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

Top

Relation with survival for SCPEP1

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

Top

RelatedDrugs for SCPEP1

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

RelatedDiseases for SCPEP1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene