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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

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Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ABCD4 (CAeditome ID:5826)

Gene summary for ABCD4

check button Gene summary
Gene informationGene symbol

ABCD4

Gene ID

5826

Gene nameATP binding cassette subfamily D member 4
SynonymsABC41|EST352188|MAHCJ|P70R|P79R|PMP69|PXMP1L
Cytomap

14q24.3

Type of geneprotein-coding
Descriptionlysosomal cobalamin transporter ABCD469 kDa peroxisomal ABC-transporterATP-binding cassette sub-family D member 4ATP-binding cassette, sub-family D (ALD), member 4PMP70-related proteinPXMP1-Lperoxisomal membrane protein 69
Modification date20210518
UniProtAcc

O14678

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
ABCD4

GO:0005777

Lysosomal cobalamin transporter ABCD4

19010322

ABCD4

GO:0005777

Lysosomal cobalamin transporter ABCD4

27456980

ABCD4

GO:0005765

Lysosomal cobalamin transporter ABCD4

27456980

ABCD4

GO:0005777

Lysosomal cobalamin transporter ABCD4

14533738

ABCD4

GO:0005777

Lysosomal cobalamin transporter ABCD4

9302272

ABCD4

GO:0005789

Lysosomal cobalamin transporter ABCD4

27456980


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RNA A-to-I events for ABCD4

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000119688.19

check button RNA A-to-I editing events in Cancer.
CAediting_1005719(74288835, -), CAediting_1005720(74288855, -), CAediting_1005721(74288908, -), CAediting_1005722(74288946, -), CAediting_1005723(74288949, -), CAediting_1005724(74288963, -), CAediting_1005725(74289000, -), CAediting_1005726(74289026, -), CAediting_1005727(74290748, -), CAediting_1005728(74290752, -), CAediting_1005729(74290757, -), CAediting_1005730(74290777, -), CAediting_1005731(74290790, -), CAediting_1005732(74290796, -), CAediting_1005733(74290798, -), CAediting_1005734(74290821, -), CAediting_1005735(74290872, -), CAediting_1005736(74290886, -), CAediting_1005737(74294121, -), CAediting_1005738(74294126, -), CAediting_1005739(74294138, -), CAediting_1005740(74294161, -), CAediting_1005741(74295766, -), CAediting_1005742(74296789, -), CAediting_1005743(74296901, -), CAediting_1005744(74297596, -), CAediting_1005745(74297611, -), CAediting_1005746(74297684, -), CAediting_1005747(74297692, -), CAediting_1005748(74297698, -), CAediting_1005749(74297873, -), CAediting_1005750(74298340, -), CAediting_1005751(74298453, -), CAediting_1005752(74298474, -), CAediting_1005753(74298529, -), CAediting_1005754(74298544, -), CAediting_1005755(74298552, -), CAediting_1005756(74299827, -), CAediting_1005757(74299890, -), CAediting_1005758(74299895, -), CAediting_1005759(74299896, -), CAediting_1005760(74299938, -), CAediting_1005761(74299939, -), CAediting_1005762(74300011, -), CAediting_1005763(74300464, -), CAediting_1005764(74300470, -), CAediting_1005765(74300529, -), CAediting_1005766(74301031, -), CAediting_1005767(74301058, -), CAediting_1005768(74301220, -), CAediting_1005769(74301245, -), CAediting_1005770(74301306, -), CAediting_1005771(74301319, -), CAediting_1005772(74301324, -), CAediting_1005773(74301342, -), CAediting_1005774(74301379, -), CAediting_1005775(74301392, -), CAediting_1005776(74301690, -), CAediting_1005777(74301743, -), CAediting_1005778(74301757, -), CAediting_1005779(74301761, -), CAediting_1005780(74301779, -), CAediting_1005781(74301789, -), CAediting_1005782(74301792, -), CAediting_1005783(74301819, -), CAediting_1005784(74301852, -), CAediting_1005785(74301861, -),

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RNA editing positional annotations for ABCD4 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1005719chr14_74288835_-ncRNA_exonic
CAediting_1005720chr14_74288855_-ncRNA_exonic
CAediting_1005721chr14_74288908_-ncRNA_exonic
CAediting_1005722chr14_74288946_-ncRNA_exonic
CAediting_1005723chr14_74288949_-ncRNA_exonic
CAediting_1005724chr14_74288963_-ncRNA_exonic
CAediting_1005725chr14_74289000_-ncRNA_exonic
CAediting_1005726chr14_74289026_-ncRNA_exonic
CAediting_1005727chr14_74290748_-ncRNA_intronic
CAediting_1005728chr14_74290752_-ncRNA_intronic
CAediting_1005729chr14_74290757_-ncRNA_intronic
CAediting_1005730chr14_74290777_-ncRNA_intronic
CAediting_1005731chr14_74290790_-ncRNA_intronic
CAediting_1005732chr14_74290796_-ncRNA_intronic
CAediting_1005733chr14_74290798_-ncRNA_intronic
CAediting_1005734chr14_74290821_-ncRNA_intronic
CAediting_1005735chr14_74290872_-ncRNA_intronic
CAediting_1005736chr14_74290886_-ncRNA_intronic
CAediting_1005737chr14_74294121_-ncRNA_exonic
CAediting_1005738chr14_74294126_-ncRNA_exonic
CAediting_1005739chr14_74294138_-ncRNA_exonic
CAediting_1005740chr14_74294161_-ncRNA_exonic
CAediting_1005741chr14_74295766_-ncRNA_exonic
CAediting_1005742chr14_74296789_-ncRNA_exonic
CAediting_1005743chr14_74296901_-ncRNA_exonic
CAediting_1005744chr14_74297596_-ncRNA_exonic
CAediting_1005745chr14_74297611_-ncRNA_exonic
CAediting_1005746chr14_74297684_-ncRNA_exonic
CAediting_1005747chr14_74297692_-ncRNA_exonic
CAediting_1005748chr14_74297698_-ncRNA_exonic
CAediting_1005749chr14_74297873_-ncRNA_exonic
CAediting_1005750chr14_74298340_-ncRNA_intronic
CAediting_1005751chr14_74298453_-ncRNA_intronic
CAediting_1005752chr14_74298474_-ncRNA_intronic
CAediting_1005753chr14_74298529_-ncRNA_intronic
CAediting_1005754chr14_74298544_-ncRNA_intronic
CAediting_1005755chr14_74298552_-ncRNA_intronic
CAediting_1005756chr14_74299827_-ncRNA_intronic
CAediting_1005757chr14_74299890_-ncRNA_intronic
CAediting_1005758chr14_74299895_-ncRNA_intronic
CAediting_1005759chr14_74299896_-ncRNA_intronic
CAediting_1005760chr14_74299938_-ncRNA_exonic
CAediting_1005761chr14_74299939_-ncRNA_exonic
CAediting_1005762chr14_74300011_-ncRNA_exonic
CAediting_1005763chr14_74300464_-ncRNA_intronic
CAediting_1005764chr14_74300470_-ncRNA_intronic
CAediting_1005765chr14_74300529_-ncRNA_intronic
CAediting_1005766chr14_74301031_-ncRNA_intronic
CAediting_1005767chr14_74301058_-ncRNA_intronic
CAediting_1005768chr14_74301220_-ncRNA_intronic
CAediting_1005769chr14_74301245_-ncRNA_intronic
CAediting_1005770chr14_74301306_-ncRNA_intronic
CAediting_1005771chr14_74301319_-ncRNA_intronic
CAediting_1005772chr14_74301324_-ncRNA_intronic
CAediting_1005773chr14_74301342_-ncRNA_intronic
CAediting_1005774chr14_74301379_-ncRNA_intronic
CAediting_1005775chr14_74301392_-ncRNA_intronic
CAediting_1005776chr14_74301690_-ncRNA_intronic
CAediting_1005777chr14_74301743_-ncRNA_intronic
CAediting_1005778chr14_74301757_-ncRNA_intronic
CAediting_1005779chr14_74301761_-ncRNA_intronic
CAediting_1005780chr14_74301779_-ncRNA_intronic
CAediting_1005781chr14_74301789_-ncRNA_intronic
CAediting_1005782chr14_74301792_-ncRNA_intronic
CAediting_1005783chr14_74301819_-ncRNA_intronic
CAediting_1005784chr14_74301852_-ncRNA_intronic
CAediting_1005785chr14_74301861_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1005719chr14_74288835_-SINEAluAluSg
CAediting_1005720chr14_74288855_-SINEAluAluSg
CAediting_1005721chr14_74288908_-SINEAluAluSg
CAediting_1005722chr14_74288946_-SINEAluAluSg
CAediting_1005723chr14_74288949_-SINEAluAluSg
CAediting_1005724chr14_74288963_-SINEAluAluSg
CAediting_1005725chr14_74289000_-SINEAluAluSg
CAediting_1005726chr14_74289026_-SINEAluAluSg
CAediting_1005727chr14_74290748_-SINEAluAluSx1
CAediting_1005728chr14_74290752_-SINEAluAluSx1
CAediting_1005729chr14_74290757_-SINEAluAluSx1
CAediting_1005730chr14_74290777_-SINEAluAluSx1
CAediting_1005731chr14_74290790_-SINEAluAluSx1
CAediting_1005732chr14_74290796_-SINEAluAluSx1
CAediting_1005733chr14_74290798_-SINEAluAluSx1
CAediting_1005734chr14_74290821_-SINEAluAluSx1
CAediting_1005735chr14_74290872_-SINEAluAluSx1
CAediting_1005736chr14_74290886_-SINEAluAluSx1
CAediting_1005737chr14_74294121_-SINEAluAluSx1
CAediting_1005738chr14_74294126_-SINEAluAluSx1
CAediting_1005739chr14_74294138_-SINEAluAluSx1
CAediting_1005740chr14_74294161_-SINEAluAluSx1
CAediting_1005741chr14_74295766_-SINEMIRMIR
CAediting_1005743chr14_74296901_-SINEAluAluSx3
CAediting_1005744chr14_74297596_-SINEAluFAM
CAediting_1005745chr14_74297611_-SINEAluFAM
CAediting_1005746chr14_74297684_-SINEAluFAM
CAediting_1005747chr14_74297692_-SINEAluFAM
CAediting_1005748chr14_74297698_-SINEAluFAM
CAediting_1005750chr14_74298340_-SINEAluAluSp
CAediting_1005751chr14_74298453_-SINEAluAluSp
CAediting_1005752chr14_74298474_-SINEAluAluSp
CAediting_1005753chr14_74298529_-SINEAluAluSp
CAediting_1005754chr14_74298544_-SINEAluAluSp
CAediting_1005755chr14_74298552_-SINEAluAluSp
CAediting_1005756chr14_74299827_-SINEAluAluSq
CAediting_1005757chr14_74299890_-SINEAluAluSq
CAediting_1005758chr14_74299895_-SINEAluAluSq
CAediting_1005759chr14_74299896_-SINEAluAluSq
CAediting_1005760chr14_74299938_-SINEAluAluSq
CAediting_1005761chr14_74299939_-SINEAluAluSq
CAediting_1005762chr14_74300011_-SINEAluAluSq
CAediting_1005763chr14_74300464_-SINEAluAluSp
CAediting_1005764chr14_74300470_-SINEAluAluSp
CAediting_1005765chr14_74300529_-SINEAluAluSp
CAediting_1005766chr14_74301031_-SINEAluAluSq2
CAediting_1005767chr14_74301058_-SINEAluAluSq2
CAediting_1005768chr14_74301220_-SINEAluAluSz
CAediting_1005769chr14_74301245_-SINEAluAluSz
CAediting_1005770chr14_74301306_-SINEAluAluSz
CAediting_1005771chr14_74301319_-SINEAluAluSz
CAediting_1005772chr14_74301324_-SINEAluAluSz
CAediting_1005773chr14_74301342_-SINEAluAluSz
CAediting_1005774chr14_74301379_-SINEAluAluSz
CAediting_1005775chr14_74301392_-SINEAluAluSz
CAediting_1005776chr14_74301690_-SINEAluAluSq
CAediting_1005777chr14_74301743_-SINEAluAluSq
CAediting_1005778chr14_74301757_-SINEAluAluSq
CAediting_1005779chr14_74301761_-SINEAluAluSq
CAediting_1005780chr14_74301779_-SINEAluAluSq
CAediting_1005781chr14_74301789_-SINEAluAluSq
CAediting_1005782chr14_74301792_-SINEAluAluSq
CAediting_1005783chr14_74301819_-SINEAluAluSq
CAediting_1005784chr14_74301852_-SINEAluAluSq
CAediting_1005785chr14_74301861_-SINEAluAluSq

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RNA A-to-I editing events in the alternative splicing sites for ABCD4

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength
ESCAediting_1005722chr14_74288946_-74288945:742889673SS2+0iCCTAATTTTTGTATATTTAGTAG2.84CCTAATTTTTGTATATTTAGTGG4.17
IRCAediting_1005722chr14_74288946_-74288945:742889673SS2+0iCCTAATTTTTGTATATTTAGTAG2.84CCTAATTTTTGTATATTTAGTGG4.17
ESCAediting_1005723chr14_74288949_-74288945:742889673SS0+2iCCTAATTTTTGTATATTTAGTAG2.84CCTAATTTTTGTATATTTGGTAG-5.12
IRCAediting_1005723chr14_74288949_-74288945:742889673SS0+2iCCTAATTTTTGTATATTTAGTAG2.84CCTAATTTTTGTATATTTGGTAG-5.12
ESCAediting_1005724chr14_74288963_-74288945:742889673SS0+16iCCTAATTTTTGTATATTTAGTAG2.84CCTAGTTTTTGTATATTTAGTAG1.85
IRCAediting_1005724chr14_74288963_-74288945:742889673SS0+16iCCTAATTTTTGTATATTTAGTAG2.84CCTAGTTTTTGTATATTTAGTAG1.85

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000119688.19.ABCD4.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000119688.19.ABCD4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ABCD4

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.
LGG.CAediting_1005748.ENSG00000119688.ABCD4.png
Soverview

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Protein coding region RNA A-to-I editings for ABCD4

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for ABCD4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1005748chr14_74297698_-ENSG00000119688.19ENST00000470637hsa-miR-140-3p74297696742977027mer-m87429769574297715152.00-24.17
CAediting_1005749chr14_74297873_-ENSG00000119688.19ENST00000470637hsa-miR-197274297873742978797mer-m87429787274297893150.00-23.31
CAediting_1005749chr14_74297873_-ENSG00000119688.19ENST00000470637hsa-miR-197274297873742978797mer-m87429787274297893150.00-23.31
CAediting_1005749chr14_74297873_-ENSG00000119688.19ENST00000470637hsa-miR-4640-5p74297869742978757mer-m87429786874297891150.00-28.51
CAediting_1005749chr14_74297873_-ENSG00000119688.19ENST00000470637hsa-miR-4726-5p74297869742978757mer-m87429786874297886147.00-26.06
CAediting_1005749chr14_74297873_-ENSG00000119688.19ENST00000470637hsa-miR-4755-3p74297871742978777mer-m87429787074297890169.00-26.84

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1005746chr14_74297684_-ENSG00000119688.19ENST00000470637hsa-miR-120074297681742976877mer-m87429768074297701145-16.48
CAediting_1005747chr14_74297692_-ENSG00000119688.19ENST00000470637hsa-miR-312274297691742976977mer-m87429769074297711154-21.4
CAediting_1005747chr14_74297692_-ENSG00000119688.19ENST00000470637hsa-miR-3913-5p74297691742976977mer-m87429769074297712151-20.12
CAediting_1005747chr14_74297692_-ENSG00000119688.19ENST00000470637hsa-miR-3913-5p74297691742976977mer-m87429769074297712151-20.12
CAediting_1005747chr14_74297692_-ENSG00000119688.19ENST00000470637hsa-miR-442574297689742976968mer-1a7429768974297708154-23.62
CAediting_1005749chr14_74297873_-ENSG00000119688.19ENST00000470637hsa-miR-570474297873742978797mer-m87429787274297893140-13.53
CAediting_1005749chr14_74297873_-ENSG00000119688.19ENST00000470637hsa-miR-606974297870742978767mer-m87429786974297888143-20.08
CAediting_1005747chr14_74297692_-ENSG00000119688.19ENST00000470637hsa-miR-6513-5p74297691742976966mer7429769074297712141-19.8
CAediting_1005748chr14_74297698_-ENSG00000119688.19ENST00000470637hsa-miR-805274297692742976987mer-1a7429769274297712153-25.18

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1306324chr19_13836464_-ENSG00000119688.19ENST00000481935hsa-miR-27a-3p74292320742923267mer-m87429231974292340141-18.39
CAediting_393chr1_1167164_+ENSG00000119688.19ENST00000481935hsa-miR-200b-3p74290458742904647mer-m87429045774290480141-16.27
CAediting_1306324chr19_13836464_-ENSG00000119688.19ENST00000553486hsa-miR-27a-3p74292320742923267mer-m87429231974292340141-18.39
CAediting_393chr1_1167164_+ENSG00000119688.19ENST00000553486hsa-miR-200b-3p74290458742904647mer-m87429045774290480141-16.27
CAediting_1306324chr19_13836464_-ENSG00000119688.19ENST00000553745hsa-miR-27a-3p74292320742923267mer-m87429231974292340141-18.39
CAediting_393chr1_1167164_+ENSG00000119688.19ENST00000553745hsa-miR-200b-3p74290458742904647mer-m87429045774290480141-16.27
CAediting_1306324chr19_13836464_-ENSG00000119688.19ENST00000469672hsa-miR-27a-3p74292320742923267mer-m87429231974292340141-18.39
CAediting_393chr1_1167164_+ENSG00000119688.19ENST00000469672hsa-miR-200b-3p74290458742904647mer-m87429045774290480141-16.27
CAediting_1306324chr19_13836464_-ENSG00000119688.19ENST00000556119hsa-miR-27a-3p74292320742923267mer-m87429231974292340141-18.39
CAediting_1229415chr17_67471547_+ENSG00000119688.19ENST00000481348hsa-miR-548aa74286449742864557mer-m87428644874286471161-13.05
CAediting_228905chr2_188297554_+ENSG00000119688.19ENST00000481348hsa-miR-561-3p74286505742865117mer-m87428650474286525160-18.64
CAediting_573000chr7_92204081_-ENSG00000119688.19ENST00000481935hsa-miR-1285-5p74292317742923237mer-m87429231674292336147-18.43
CAediting_1054808chr15_66496985_-ENSG00000119688.19ENST00000481935hsa-miR-451274286626742866327mer-m87428662574286646148-23.28
CAediting_1229415chr17_67471547_+ENSG00000119688.19ENST00000481935hsa-miR-548aa74286449742864557mer-m87428644874286471161-13.05
CAediting_228905chr2_188297554_+ENSG00000119688.19ENST00000481935hsa-miR-561-3p74286505742865117mer-m87428650474286525160-18.64
CAediting_573000chr7_92204081_-ENSG00000119688.19ENST00000553486hsa-miR-1285-5p74292317742923237mer-m87429231674292336147-18.43
CAediting_1229415chr17_67471547_+ENSG00000119688.19ENST00000553486hsa-miR-548aa74286449742864557mer-m87428644874286471161-13.05
CAediting_228905chr2_188297554_+ENSG00000119688.19ENST00000553486hsa-miR-561-3p74286505742865117mer-m87428650474286525160-18.64
CAediting_1054808chr15_66496985_-ENSG00000119688.19ENST00000556517hsa-miR-451274286626742866327mer-m87428662574286646148-23.28
CAediting_1229415chr17_67471547_+ENSG00000119688.19ENST00000556517hsa-miR-548aa74286449742864557mer-m87428644874286471161-13.05
CAediting_228905chr2_188297554_+ENSG00000119688.19ENST00000556517hsa-miR-561-3p74286505742865117mer-m87428650474286525160-18.64
CAediting_573000chr7_92204081_-ENSG00000119688.19ENST00000553745hsa-miR-1285-5p74292317742923237mer-m87429231674292336147-18.43
CAediting_1054808chr15_66496985_-ENSG00000119688.19ENST00000553745hsa-miR-451274286626742866327mer-m87428662574286646148-23.28
CAediting_573000chr7_92204081_-ENSG00000119688.19ENST00000469672hsa-miR-1285-5p74292317742923237mer-m87429231674292336147-18.43
CAediting_573000chr7_92204081_-ENSG00000119688.19ENST00000556119hsa-miR-1285-5p74292317742923237mer-m87429231674292336147-18.43
CAediting_468389chr6_31355314_-ENSG00000119688.19ENST00000481935hsa-miR-6891-5p74286580742865867mer-m87428657974286597140-17
CAediting_468389chr6_31355314_-ENSG00000119688.19ENST00000556517hsa-miR-6891-5p74286580742865867mer-m87428657974286597140-17
CAediting_468389chr6_31355314_-ENSG00000119688.19ENST00000553745hsa-miR-6891-5p74286580742865867mer-m87428657974286597140-17

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_468389chr6_31355314_-ENSG00000119688.19ENST00000481935hsa-miR-6891-5p74290329742903357mer-m87429032874290346140-16.05
CAediting_468389chr6_31355314_-ENSG00000119688.19ENST00000553486hsa-miR-6891-5p74290329742903357mer-m87429032874290346140-16.05
CAediting_468389chr6_31355314_-ENSG00000119688.19ENST00000553745hsa-miR-6891-5p74290329742903357mer-m87429032874290346140-16.05

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ABCD4

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for ABCD4

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
OVCAediting_1005748chr14_74297698_-0.01675413458356020.302785226932738....

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Relation with cancer stages for ABCD4

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.
ESCApathologic_stageCAediting_1005748chr14_74297698_-0.003821201457621920.390713916196432

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Relation with survival for ABCD4

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ABCD4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ABCD4

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
ABCD4C3553915METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA, cblJ TYPE3CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
ABCD4C0009402Colorectal Carcinoma1CTD_human
ABCD4C0009404Colorectal Neoplasms1CTD_human
ABCD4C0025521Inborn Errors of Metabolism1CTD_human
ABCD4C0042847Vitamin B 12 Deficiency1CTD_human
ABCD4C0235874Disease Exacerbation1CTD_human