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Editing gene: UVSSA (CAeditome ID:57654)

Gene summary for UVSSA

Gene summary

Gene information	Gene symbol	UVSSA
	Gene ID	57654
	Gene name	UV stimulated scaffold protein A
	Synonyms	KIAA1530\|UVSS3
	Cytomap	4p16.3
	Type of gene	protein-coding
	Description	UV-stimulated scaffold protein A
	Modification date	20210518
	UniProtAcc	Q2YD98
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
UVSSA	GO:0000993	UV-stimulated scaffold protein A	22466611
UVSSA	GO:0000993	UV-stimulated scaffold protein A	22466612
UVSSA	GO:0005654	UV-stimulated scaffold protein A	0000052
UVSSA	GO:0005694	UV-stimulated scaffold protein A	22466611
UVSSA	GO:0005694	UV-stimulated scaffold protein A	22466612

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RNA A-to-I events for UVSSA

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000163945.14

RNA A-to-I editing events in Cancer.

CAediting_345041(1350743, +), CAediting_345042(1350748, +), CAediting_345043(1350751, +), CAediting_345044(1351023, +), CAediting_345045(1351588, +), CAediting_345046(1352824, +), CAediting_345047(1386758, +), CAediting_345048(1386768, +), CAediting_345049(1386782, +), CAediting_345050(1386787, +), CAediting_345051(1386792, +), CAediting_345052(1386797, +), CAediting_345053(1386818, +), CAediting_345054(1386830, +), CAediting_345055(1386835, +), CAediting_345056(1386859, +), CAediting_345057(1386865, +), CAediting_345058(1386867, +), CAediting_345059(1386873, +), CAediting_345060(1386947, +), CAediting_345061(1386954, +), CAediting_345062(1386993, +), CAediting_345063(1386999, +), CAediting_345064(1387006, +), CAediting_345065(1387098, +), CAediting_345066(1387099, +), CAediting_345067(1387104, +), CAediting_345068(1387121, +), CAediting_345069(1387128, +), CAediting_345070(1387142, +), CAediting_345071(1387152, +), CAediting_345072(1387157, +), CAediting_345073(1387158, +), CAediting_345074(1387164, +), CAediting_345075(1387178, +), CAediting_345076(1387204, +), CAediting_345077(1387207, +), CAediting_345078(1387217, +), CAediting_345079(1387227, +), CAediting_345080(1387233, +), CAediting_345081(1387243, +), CAediting_345082(1387252, +), CAediting_345083(1387261, +), CAediting_345084(1387275, +), CAediting_345085(1387323, +), CAediting_345086(1387350, +),

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RNA editing positional annotations for UVSSA using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_345041	chr4_1350743_+	intronic
CAediting_345042	chr4_1350748_+	intronic
CAediting_345043	chr4_1350751_+	intronic
CAediting_345044	chr4_1351023_+	intronic
CAediting_345045	chr4_1351588_+	intronic
CAediting_345046	chr4_1352824_+	intronic
CAediting_345047	chr4_1386758_+	UTR3
CAediting_345048	chr4_1386768_+	UTR3
CAediting_345049	chr4_1386782_+	UTR3
CAediting_345050	chr4_1386787_+	UTR3
CAediting_345051	chr4_1386792_+	UTR3
CAediting_345052	chr4_1386797_+	UTR3
CAediting_345053	chr4_1386818_+	UTR3
CAediting_345054	chr4_1386830_+	UTR3
CAediting_345055	chr4_1386835_+	UTR3
CAediting_345056	chr4_1386859_+	UTR3
CAediting_345057	chr4_1386865_+	UTR3
CAediting_345058	chr4_1386867_+	UTR3
CAediting_345059	chr4_1386873_+	UTR3
CAediting_345060	chr4_1386947_+	UTR3
CAediting_345061	chr4_1386954_+	UTR3
CAediting_345062	chr4_1386993_+	UTR3
CAediting_345063	chr4_1386999_+	UTR3
CAediting_345064	chr4_1387006_+	UTR3
CAediting_345065	chr4_1387098_+	UTR3
CAediting_345066	chr4_1387099_+	UTR3
CAediting_345067	chr4_1387104_+	UTR3
CAediting_345068	chr4_1387121_+	UTR3
CAediting_345069	chr4_1387128_+	UTR3
CAediting_345070	chr4_1387142_+	UTR3
CAediting_345071	chr4_1387152_+	UTR3
CAediting_345072	chr4_1387157_+	UTR3
CAediting_345073	chr4_1387158_+	UTR3
CAediting_345074	chr4_1387164_+	UTR3
CAediting_345075	chr4_1387178_+	UTR3
CAediting_345076	chr4_1387204_+	UTR3
CAediting_345077	chr4_1387207_+	UTR3
CAediting_345078	chr4_1387217_+	UTR3
CAediting_345079	chr4_1387227_+	UTR3
CAediting_345080	chr4_1387233_+	UTR3
CAediting_345081	chr4_1387243_+	UTR3
CAediting_345082	chr4_1387252_+	UTR3
CAediting_345083	chr4_1387261_+	UTR3
CAediting_345084	chr4_1387275_+	UTR3
CAediting_345085	chr4_1387323_+	UTR3
CAediting_345086	chr4_1387350_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_345041	chr4_1350743_+	SINE	Alu	FLAM_A
CAediting_345042	chr4_1350748_+	SINE	Alu	FLAM_A
CAediting_345043	chr4_1350751_+	SINE	Alu	FLAM_A
CAediting_345044	chr4_1351023_+	SINE	Alu	AluSx3
CAediting_345045	chr4_1351588_+	SINE	Alu	AluYf1
CAediting_345046	chr4_1352824_+	SINE	Alu	AluJr
CAediting_345047	chr4_1386758_+	SINE	Alu	AluJr
CAediting_345048	chr4_1386768_+	SINE	Alu	AluJr
CAediting_345049	chr4_1386782_+	SINE	Alu	AluJr
CAediting_345050	chr4_1386787_+	SINE	Alu	AluJr
CAediting_345051	chr4_1386792_+	SINE	Alu	AluJr
CAediting_345052	chr4_1386797_+	SINE	Alu	AluJr
CAediting_345053	chr4_1386818_+	SINE	Alu	AluJr
CAediting_345054	chr4_1386830_+	SINE	Alu	AluJr
CAediting_345055	chr4_1386835_+	SINE	Alu	AluJr
CAediting_345056	chr4_1386859_+	SINE	Alu	AluJr
CAediting_345057	chr4_1386865_+	SINE	Alu	AluJr
CAediting_345058	chr4_1386867_+	SINE	Alu	AluJr
CAediting_345059	chr4_1386873_+	SINE	Alu	AluJr
CAediting_345060	chr4_1386947_+	SINE	Alu	AluJr
CAediting_345061	chr4_1386954_+	SINE	Alu	AluJr
CAediting_345062	chr4_1386993_+	SINE	Alu	AluJr
CAediting_345063	chr4_1386999_+	SINE	Alu	AluJr
CAediting_345064	chr4_1387006_+	SINE	Alu	AluJr
CAediting_345065	chr4_1387098_+	SINE	Alu	AluSc
CAediting_345066	chr4_1387099_+	SINE	Alu	AluSc
CAediting_345067	chr4_1387104_+	SINE	Alu	AluSc
CAediting_345068	chr4_1387121_+	SINE	Alu	AluSc
CAediting_345069	chr4_1387128_+	SINE	Alu	AluSc
CAediting_345070	chr4_1387142_+	SINE	Alu	AluSc
CAediting_345071	chr4_1387152_+	SINE	Alu	AluSc
CAediting_345072	chr4_1387157_+	SINE	Alu	AluSc
CAediting_345073	chr4_1387158_+	SINE	Alu	AluSc
CAediting_345074	chr4_1387164_+	SINE	Alu	AluSc
CAediting_345075	chr4_1387178_+	SINE	Alu	AluSc
CAediting_345076	chr4_1387204_+	SINE	Alu	AluSc
CAediting_345077	chr4_1387207_+	SINE	Alu	AluSc
CAediting_345078	chr4_1387217_+	SINE	Alu	AluSc
CAediting_345079	chr4_1387227_+	SINE	Alu	AluSc
CAediting_345080	chr4_1387233_+	SINE	Alu	AluSc
CAediting_345081	chr4_1387243_+	SINE	Alu	AluSc
CAediting_345082	chr4_1387252_+	SINE	Alu	AluSc
CAediting_345083	chr4_1387261_+	SINE	Alu	AluSc
CAediting_345084	chr4_1387275_+	SINE	Alu	AluSc
CAediting_345085	chr4_1387323_+	SINE	Alu	AluSc
CAediting_345086	chr4_1387350_+	SINE	Alu	AluSc

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RNA A-to-I editing events in the alternative splicing sites for UVSSA

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_345067	chr4_1387104_+	1387102:1387124	3SS	0+18i	GGAATCTTGCTCTGTCGCCAGGC	-10.38	GGGATCTTGCTCTGTCGCCAGGC	-10
IR	CAediting_345068	chr4_1387121_+	1387102:1387124	3SS	0+1i	GGAATCTTGCTCTGTCGCCAGGC	-10.38	GGAATCTTGCTCTGTCGCCGGGC	-1.63

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000163945.14.UVSSA.

Correlation between RNA A-to-I editing and PSI for ENSG00000163945.14.UVSSA.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for UVSSA

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for UVSSA

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for UVSSA

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_345050	chr4_1386787_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6807-5p	1386785	1386791	7mer-m8	1386772	1386792	142.00	-15.08
CAediting_345052	chr4_1386797_+	ENSG00000163945.14	ENST00000503548	hsa-miR-106b-3p	1386790	1386796	7mer-m8	1386777	1386797	144.00	-21.18
CAediting_345048	chr4_1386768_+	ENSG00000163945.14	ENST00000503548	hsa-miR-500b-3p	1386764	1386770	7mer-m8	1386752	1386771	146.00	-21.18
CAediting_345048	chr4_1386768_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6849-3p	1386761	1386767	7mer-m8	1386747	1386768	152.00	-16.94
CAediting_345049	chr4_1386782_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3664-5p	1386777	1386782	6mer	1386760	1386783	148.00	-21.41
CAediting_345049	chr4_1386782_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4522	1386777	1386784	8mer-1a	1386762	1386784	154.00	-25.66
CAediting_345049	chr4_1386782_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6728-3p	1386776	1386781	6mer	1386761	1386782	147.00	-25.10
CAediting_345053	chr4_1386818_+	ENSG00000163945.14	ENST00000503548	hsa-miR-1199-5p	1386811	1386817	7mer-m8	1386799	1386818	156.00	-28.57
CAediting_345053	chr4_1386818_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6751-3p	1386811	1386817	7mer-m8	1386798	1386818	141.00	-13.15
CAediting_345054	chr4_1386830_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6125	1386823	1386829	7mer-m8	1386811	1386830	140.00	-20.65
CAediting_345060	chr4_1386947_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4433a-3p	1386940	1386946	7mer-m8	1386927	1386947	145.00	-19.72
CAediting_345060	chr4_1386947_+	ENSG00000163945.14	ENST00000503548	hsa-miR-665	1386941	1386947	7mer-m8	1386929	1386948	153.00	-24.98
CAediting_345061	chr4_1386954_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4649-3p	1386947	1386953	7mer-m8	1386934	1386954	140.00	-14.53
CAediting_345061	chr4_1386954_+	ENSG00000163945.14	ENST00000503548	hsa-miR-544b	1386948	1386954	7mer-m8	1386935	1386955	157.00	-17.71
CAediting_345061	chr4_1386954_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6078	1386950	1386957	8mer-1a	1386938	1386957	160.00	-23.09
CAediting_345066	chr4_1387099_+	ENSG00000163945.14	ENST00000503548	hsa-miR-371b-5p	1387092	1387099	8mer-1a	1387079	1387099	143.00	-7.98
CAediting_345066	chr4_1387099_+	ENSG00000163945.14	ENST00000503548	hsa-miR-373-5p	1387092	1387099	8mer-1a	1387078	1387099	140.00	-8.35
CAediting_345066	chr4_1387099_+	ENSG00000163945.14	ENST00000503548	hsa-miR-514b-5p	1387094	1387099	6mer	1387079	1387100	143.00	-10.29
CAediting_345066	chr4_1387099_+	ENSG00000163945.14	ENST00000503548	hsa-miR-616-5p	1387092	1387099	8mer-1a	1387078	1387099	140.00	-6.13
CAediting_345068	chr4_1387121_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3940-3p	1387118	1387124	7mer-m8	1387105	1387125	145.00	-23.40
CAediting_345070	chr4_1387142_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4786-5p	1387139	1387145	7mer-m8	1387127	1387146	149.00	-22.21
CAediting_345073	chr4_1387158_+	ENSG00000163945.14	ENST00000503548	hsa-miR-17-3p	1387151	1387157	7mer-m8	1387137	1387158	150.00	-18.47
CAediting_345075	chr4_1387178_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4539	1387172	1387177	6mer	1387159	1387178	141.00	-18.80
CAediting_345075	chr4_1387178_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6078	1387174	1387181	8mer-1a	1387162	1387181	148.00	-20.43
CAediting_345076	chr4_1387204_+	ENSG00000163945.14	ENST00000503548	hsa-miR-1915-3p	1387199	1387204	6mer	1387182	1387205	148.00	-34.91
CAediting_345076	chr4_1387204_+	ENSG00000163945.14	ENST00000503548	hsa-miR-665	1387198	1387203	6mer	1387185	1387204	140.00	-24.96
CAediting_345076	chr4_1387204_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6840-3p	1387198	1387204	7mer-m8	1387183	1387205	166.00	-32.27
CAediting_345077	chr4_1387207_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4691-3p	1387204	1387210	7mer-m8	1387187	1387211	146.00	-26.52
CAediting_345078	chr4_1387217_+	ENSG00000163945.14	ENST00000503548	hsa-miR-17-3p	1387213	1387219	7mer-m8	1387198	1387220	150.00	-22.27
CAediting_345081	chr4_1387243_+	ENSG00000163945.14	ENST00000503548	hsa-miR-1207-3p	1387236	1387243	8mer-1a	1387226	1387243	144.00	-14.68
CAediting_345081	chr4_1387243_+	ENSG00000163945.14	ENST00000503548	hsa-miR-34a-3p	1387239	1387245	7mer-m8	1387225	1387246	140.00	-8.12
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-1285-3p	1386756	1386762	7mer-m8	1386742	1386763	152.00	-21.30
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-1285-3p	1386756	1386762	7mer-m8	1386742	1386763	152.00	-21.30
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-31-5p	1386753	1386759	7mer-m8	1386739	1386760	141.00	-16.21
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3187-5p	1386756	1386762	7mer-m8	1386742	1386763	142.00	-23.08
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-335-5p	1386751	1386757	7mer-m8	1386736	1386758	154.00	-13.69
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-5189-5p	1386756	1386762	7mer-m8	1386740	1386763	158.00	-23.21
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-612	1386756	1386762	7mer-m8	1386740	1386763	152.00	-26.81
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6809-5p	1386754	1386759	6mer	1386739	1386760	140.00	-18.64
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6860	1386756	1386762	7mer-m8	1386741	1386763	149.00	-20.64
CAediting_345064	chr4_1387006_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6770-3p	1387002	1387008	7mer-m8	1386988	1387009	158.00	-22.84
CAediting_345064	chr4_1387006_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6770-3p	1387002	1387008	7mer-m8	1386988	1387009	158.00	-22.84
CAediting_345064	chr4_1387006_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6770-3p	1387002	1387008	7mer-m8	1386988	1387009	158.00	-22.84
CAediting_345080	chr4_1387233_+	ENSG00000163945.14	ENST00000503548	hsa-miR-10394-3p	1387231	1387238	8mer-1a	1387217	1387238	145.00	-27.05
CAediting_345080	chr4_1387233_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3178	1387231	1387238	8mer-1a	1387222	1387238	145.00	-25.56

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_345076	chr4_1387204_+	ENSG00000163945.14	ENST00000503548	hsa-miR-1266-5p	1387199	1387204	6mer	1387183	1387205	141	-24
CAediting_345053	chr4_1386818_+	ENSG00000163945.14	ENST00000503548	hsa-miR-135a-5p	1386816	1386822	7mer-m8	1386801	1386823	140	-11.49
CAediting_345053	chr4_1386818_+	ENSG00000163945.14	ENST00000503548	hsa-miR-135a-5p	1386816	1386822	7mer-m8	1386801	1386823	140	-11.49
CAediting_345053	chr4_1386818_+	ENSG00000163945.14	ENST00000503548	hsa-miR-135b-5p	1386816	1386822	7mer-m8	1386801	1386823	140	-11.49
CAediting_345056	chr4_1386859_+	ENSG00000163945.14	ENST00000503548	hsa-miR-20b-3p	1386853	1386859	7mer-m8	1386838	1386860	153	-21.75
CAediting_345078	chr4_1387217_+	ENSG00000163945.14	ENST00000503548	hsa-miR-20b-3p	1387213	1387219	7mer-m8	1387198	1387220	153	-18.04
CAediting_345084	chr4_1387275_+	ENSG00000163945.14	ENST00000503548	hsa-miR-216a-3p	1387273	1387279	7mer-m8	1387259	1387280	148	-19.3
CAediting_345071	chr4_1387152_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3174	1387148	1387153	6mer	1387134	1387154	142	-24.91
CAediting_345054	chr4_1386830_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3190-3p	1386824	1386830	7mer-m8	1386812	1386831	149	-24.78
CAediting_345076	chr4_1387204_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3664-3p	1387198	1387204	7mer-m8	1387183	1387205	145	-16.21
CAediting_345084	chr4_1387275_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3681-3p	1387273	1387279	7mer-m8	1387257	1387280	143	-21
CAediting_345074	chr4_1387164_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3689d	1387162	1387168	7mer-m8	1387147	1387169	143	-14.85
CAediting_345074	chr4_1387164_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3689d	1387162	1387168	7mer-m8	1387147	1387169	143	-14.85
CAediting_345082	chr4_1387252_+	ENSG00000163945.14	ENST00000503548	hsa-miR-381-3p	1387247	1387252	6mer	1387232	1387253	140	-13.24
CAediting_345060	chr4_1386947_+	ENSG00000163945.14	ENST00000503548	hsa-miR-3975	1386945	1386952	8mer-1a	1386931	1386952	140	-12.59
CAediting_345055	chr4_1386835_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4478	1386832	1386838	7mer-m8	1386822	1386839	146	-20.39
CAediting_345074	chr4_1387164_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4536-5p	1387158	1387164	7mer-m8	1387144	1387165	146	-13.89
CAediting_345074	chr4_1387164_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4536-5p	1387158	1387164	7mer-m8	1387144	1387165	146	-13.89
CAediting_345072	chr4_1387157_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4703-3p	1387155	1387161	7mer-m8	1387141	1387162	154	-16.1
CAediting_345073	chr4_1387158_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4703-3p	1387155	1387161	7mer-m8	1387141	1387162	154	-16.1
CAediting_345052	chr4_1386797_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4793-3p	1386791	1386797	7mer-m8	1386776	1386798	151	-21.55
CAediting_345052	chr4_1386797_+	ENSG00000163945.14	ENST00000503548	hsa-miR-485-5p	1386795	1386802	8mer-1a	1386778	1386802	150	-17.49
CAediting_345069	chr4_1387128_+	ENSG00000163945.14	ENST00000503548	hsa-miR-508-5p	1387123	1387129	7mer-m8	1387107	1387130	152	-23.91
CAediting_345076	chr4_1387204_+	ENSG00000163945.14	ENST00000503548	hsa-miR-510-5p	1387199	1387206	8mer-1a	1387185	1387206	152	-19.36
CAediting_345056	chr4_1386859_+	ENSG00000163945.14	ENST00000503548	hsa-miR-550a-3-5p	1386857	1386864	8mer-1a	1386845	1386864	143	-16.2
CAediting_345056	chr4_1386859_+	ENSG00000163945.14	ENST00000503548	hsa-miR-550a-5p	1386857	1386864	8mer-1a	1386842	1386864	143	-19.13
CAediting_345056	chr4_1386859_+	ENSG00000163945.14	ENST00000503548	hsa-miR-550a-5p	1386857	1386864	8mer-1a	1386842	1386864	143	-19.13
CAediting_345057	chr4_1386865_+	ENSG00000163945.14	ENST00000503548	hsa-miR-550b-2-5p	1386858	1386864	7mer-m8	1386844	1386865	148	-17.84
CAediting_345057	chr4_1386865_+	ENSG00000163945.14	ENST00000503548	hsa-miR-550b-2-5p	1386858	1386864	7mer-m8	1386844	1386865	148	-17.84
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-555	1386754	1386761	8mer-1a	1386739	1386761	148	-13.9
CAediting_345077	chr4_1387207_+	ENSG00000163945.14	ENST00000503548	hsa-miR-5690	1387204	1387210	7mer-m8	1387191	1387211	145	-17.72
CAediting_345070	chr4_1387142_+	ENSG00000163945.14	ENST00000503548	hsa-miR-5694	1387139	1387144	6mer	1387124	1387145	142	-15.85
CAediting_345083	chr4_1387261_+	ENSG00000163945.14	ENST00000503548	hsa-miR-593-3p	1387260	1387265	6mer	1387248	1387266	140	-18.96
CAediting_345060	chr4_1386947_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6069	1386943	1386949	7mer-m8	1386930	1386950	141	-15.75
CAediting_345085	chr4_1387323_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6134	1387320	1387326	7mer-m8	1387309	1387327	154	-20.24
CAediting_345069	chr4_1387128_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6512-3p	1387121	1387127	7mer-m8	1387106	1387128	143	-19.65
CAediting_345063	chr4_1386999_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6514-3p	1386992	1386998	7mer-m8	1386979	1386999	155	-17.54
CAediting_345072	chr4_1387157_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6516-5p	1387151	1387157	7mer-m8	1387136	1387158	146	-13.83
CAediting_345073	chr4_1387158_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6516-5p	1387151	1387157	7mer-m8	1387136	1387158	146	-13.83
CAediting_345069	chr4_1387128_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6720-5p	1387121	1387127	7mer-m8	1387108	1387128	150	-28.21
CAediting_345085	chr4_1387323_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6748-5p	1387317	1387323	7mer-m8	1387299	1387324	150	-20.38
CAediting_345085	chr4_1387323_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6769a-5p	1387318	1387324	7mer-m8	1387303	1387325	142	-20.99
CAediting_345063	chr4_1386999_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6847-3p	1386997	1387003	7mer-m8	1386982	1387004	153	-22.19
CAediting_345047	chr4_1386758_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6861-5p	1386756	1386762	7mer-m8	1386740	1386763	151	-24.62
CAediting_345057	chr4_1386865_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6867-5p	1386861	1386867	7mer-m8	1386846	1386868	141	-15.62
CAediting_345058	chr4_1386867_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6867-5p	1386861	1386867	7mer-m8	1386846	1386868	141	-15.62
CAediting_345052	chr4_1386797_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6884-5p	1386795	1386802	8mer-1a	1386780	1386802	146	-18.5
CAediting_345055	chr4_1386835_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6884-5p	1386833	1386839	7mer-m8	1386817	1386840	152	-21.22
CAediting_345069	chr4_1387128_+	ENSG00000163945.14	ENST00000503548	hsa-miR-766-3p	1387122	1387128	7mer-m8	1387105	1387129	150	-22.39
CAediting_345048	chr4_1386768_+	ENSG00000163945.14	ENST00000503548	hsa-miR-7703	1386766	1386772	7mer-m8	1386752	1386773	152	-20.54

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_980496	chr14_31014685_-	ENSG00000163945.14	ENST00000507531	hsa-miR-624-3p	1386208	1386214	7mer-m8	1386195	1386215	140	-14.72
CAediting_980496	chr14_31014685_-	ENSG00000163945.14	ENST00000512728	hsa-miR-624-3p	1386208	1386214	7mer-m8	1386195	1386215	140	-14.72
CAediting_748296	chr10_51299626_+	ENSG00000163945.14	ENST00000503548	hsa-miR-605-3p	1385549	1385556	8mer-1a	1385535	1385556	140	-15.29
CAediting_980496	chr14_31014685_-	ENSG00000163945.14	ENST00000503548	hsa-miR-624-3p	1386208	1386214	7mer-m8	1386195	1386215	140	-14.72
CAediting_393	chr1_1167164_+	ENSG00000163945.14	ENST00000503548	hsa-miR-200b-3p	1386585	1386591	7mer-m8	1386570	1386592	153	-16.57
CAediting_393	chr1_1167164_+	ENSG00000163945.14	ENST00000503548	hsa-miR-200b-3p	1384153	1384159	7mer-m8	1384139	1384160	142	-12.37
CAediting_1351755	chr19_40282625_-	ENSG00000163945.14	ENST00000507531	hsa-miR-641	1386009	1386015	7mer-1a	1385993	1386015	143	-18.11
CAediting_1351755	chr19_40282625_-	ENSG00000163945.14	ENST00000512728	hsa-miR-641	1386009	1386015	7mer-1a	1385993	1386015	143	-18.11
CAediting_573001	chr7_92204086_-	ENSG00000163945.14	ENST00000512728	hsa-miR-1285-5p	1386239	1386245	7mer-m8	1386226	1386246	143	-18.33
CAediting_1054808	chr15_66496985_-	ENSG00000163945.14	ENST00000503548	hsa-miR-4512	1384780	1384786	7mer-m8	1384766	1384787	151	-26.2
CAediting_1054808	chr15_66496985_-	ENSG00000163945.14	ENST00000503548	hsa-miR-4512	1384946	1384951	6mer	1384929	1384952	143	-23.86
CAediting_1054808	chr15_66496985_-	ENSG00000163945.14	ENST00000503548	hsa-miR-4512	1385816	1385822	7mer-m8	1385802	1385823	140	-18.22
CAediting_1229414	chr17_67471546_+	ENSG00000163945.14	ENST00000503548	hsa-miR-548aa	1387290	1387296	7mer-m8	1387273	1387297	140	-13.26
CAediting_1351755	chr19_40282625_-	ENSG00000163945.14	ENST00000503548	hsa-miR-641	1385120	1385126	7mer-1a	1385103	1385126	147	-22.76
CAediting_1351755	chr19_40282625_-	ENSG00000163945.14	ENST00000503548	hsa-miR-641	1386009	1386015	7mer-1a	1385993	1386015	143	-18.11
CAediting_1351755	chr19_40282625_-	ENSG00000163945.14	ENST00000503548	hsa-miR-641	1384436	1384441	6mer	1384418	1384442	144	-24.29
CAediting_86358	chr1_109598906_+	ENSG00000163945.14	ENST00000503548	hsa-miR-197-5p	1387315	1387322	8mer-1a	1387297	1387322	154	-26.39
CAediting_396018	chr5_1062918_-	ENSG00000163945.14	ENST00000503548	hsa-miR-4635	1386948	1386954	7mer-m8	1386935	1386955	150	-14.86
CAediting_524911	chr7_5495852_-	ENSG00000163945.14	ENST00000503548	hsa-miR-589-3p	1387108	1387114	7mer-m8	1387091	1387115	166	-19.07
CAediting_573001	chr7_92204086_-	ENSG00000163945.14	ENST00000503548	hsa-miR-1285-5p	1386239	1386245	7mer-m8	1386226	1386246	143	-18.33
CAediting_468389	chr6_31355314_-	ENSG00000163945.14	ENST00000503548	hsa-miR-6891-5p	1385109	1385115	7mer-m8	1385095	1385116	147	-23.43

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000163945.14	ENST00000503548	hsa-miR-1304-3p	1384697	1384703	7mer-m8	1384682	1384704	146	-16.83
CAediting_77128	chr1_85133844_+	ENSG00000163945.14	ENST00000503548	hsa-miR-4423-3p	1385781	1385788	8mer-1a	1385768	1385788	140	-10.48
CAediting_1054808	chr15_66496985_-	ENSG00000163945.14	ENST00000503548	hsa-miR-4512	1385311	1385317	7mer-m8	1385297	1385318	142	-19.08
CAediting_1054808	chr15_66496985_-	ENSG00000163945.14	ENST00000503548	hsa-miR-4512	1386172	1386178	7mer-m8	1386157	1386179	155	-23.73
CAediting_228905	chr2_188297554_+	ENSG00000163945.14	ENST00000503548	hsa-miR-561-3p	1387067	1387074	8mer-1a	1387049	1387074	149	-9.28
CAediting_228905	chr2_188297554_+	ENSG00000163945.14	ENST00000503548	hsa-miR-561-3p	1387384	1387390	7mer-m8	1387366	1387391	145	-10.69
CAediting_1351755	chr19_40282625_-	ENSG00000163945.14	ENST00000503548	hsa-miR-641	1384397	1384403	7mer-m8	1384381	1384404	140	-10.09
CAediting_580943	chr7_100356700_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6840-3p	1387166	1387172	7mer-m8	1387152	1387173	147	-19.28
CAediting_580943	chr7_100356700_+	ENSG00000163945.14	ENST00000503548	hsa-miR-6840-3p	1384206	1384212	7mer-m8	1384192	1384213	140	-25.27

Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for UVSSA

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000389851.7	protein_coding
ENST00000503548.1	nonsense_mediated_decay

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_345047	ENST00000389851.7	chr4_1386758_+	-1738.80	-1737.50	-1799.50
CAediting_345048	ENST00000389851.7	chr4_1386768_+	-1739.20	-1737.50	-1799.50
CAediting_345049	ENST00000389851.7	chr4_1386782_+	-1739.80	-1737.50	-1799.50
CAediting_345050	ENST00000389851.7	chr4_1386787_+	-1743.70	-1737.50	-1799.50
CAediting_345051	ENST00000389851.7	chr4_1386792_+	-1738.30	-1737.50	-1799.50
CAediting_345052	ENST00000389851.7	chr4_1386797_+	-1738.70	-1737.50	-1799.50
CAediting_345053	ENST00000389851.7	chr4_1386818_+	-1740.30	-1737.50	-1799.50
CAediting_345054	ENST00000389851.7	chr4_1386830_+	-1737.80	-1737.50	-1799.50
CAediting_345055	ENST00000389851.7	chr4_1386835_+	-1738.50	-1737.50	-1799.50
CAediting_345056	ENST00000389851.7	chr4_1386859_+	-1740.50	-1737.50	-1799.50
CAediting_345057	ENST00000389851.7	chr4_1386865_+	-1738.80	-1737.50	-1799.50
CAediting_345058	ENST00000389851.7	chr4_1386867_+	-1741.20	-1737.50	-1799.50
CAediting_345059	ENST00000389851.7	chr4_1386873_+	-1740.00	-1737.50	-1799.50
CAediting_345060	ENST00000389851.7	chr4_1386947_+	-1744.10	-1737.50	-1799.50
CAediting_345061	ENST00000389851.7	chr4_1386954_+	-1737.70	-1737.50	-1799.50
CAediting_345062	ENST00000389851.7	chr4_1386993_+	-1739.90	-1737.50	-1799.50
CAediting_345063	ENST00000389851.7	chr4_1386999_+	-1737.80	-1737.50	-1799.50
CAediting_345064	ENST00000389851.7	chr4_1387006_+	-1739.50	-1737.50	-1799.50
CAediting_345065	ENST00000389851.7	chr4_1387098_+	-1738.00	-1737.50	-1799.50
CAediting_345066	ENST00000389851.7	chr4_1387099_+	-1740.40	-1737.50	-1799.50
CAediting_345067	ENST00000389851.7	chr4_1387104_+	-1739.00	-1737.50	-1799.50
CAediting_345068	ENST00000389851.7	chr4_1387121_+	-1738.30	-1737.50	-1799.50
CAediting_345069	ENST00000389851.7	chr4_1387128_+	-1741.90	-1737.50	-1799.50
CAediting_345070	ENST00000389851.7	chr4_1387142_+	-1740.20	-1737.50	-1799.50
CAediting_345071	ENST00000389851.7	chr4_1387152_+	-1738.60	-1737.50	-1799.50
CAediting_345072	ENST00000389851.7	chr4_1387157_+	-1737.80	-1737.50	-1799.50
CAediting_345073	ENST00000389851.7	chr4_1387158_+	-1742.30	-1737.50	-1799.50
CAediting_345074	ENST00000389851.7	chr4_1387164_+	-1738.90	-1737.50	-1799.50
CAediting_345075	ENST00000389851.7	chr4_1387178_+	-1743.60	-1737.50	-1799.50
CAediting_345076	ENST00000389851.7	chr4_1387204_+	-1742.80	-1737.50	-1799.50
CAediting_345077	ENST00000389851.7	chr4_1387207_+	-1740.10	-1737.50	-1799.50
CAediting_345078	ENST00000389851.7	chr4_1387217_+	-1741.60	-1737.50	-1799.50
CAediting_345079	ENST00000389851.7	chr4_1387227_+	-1740.60	-1737.50	-1799.50
CAediting_345080	ENST00000389851.7	chr4_1387233_+	-1742.90	-1737.50	-1799.50
CAediting_345081	ENST00000389851.7	chr4_1387243_+	-1738.10	-1737.50	-1799.50
CAediting_345082	ENST00000389851.7	chr4_1387252_+	-1740.00	-1737.50	-1799.50
CAediting_345083	ENST00000389851.7	chr4_1387261_+	-1738.40	-1737.50	-1799.50
CAediting_345084	ENST00000389851.7	chr4_1387275_+	-1741.50	-1737.50	-1799.50
CAediting_345085	ENST00000389851.7	chr4_1387323_+	-1737.10	-1737.50	-1799.50
CAediting_345086	ENST00000389851.7	chr4_1387350_+	-1739.30	-1737.50	-1799.50
CAediting_345047	ENST00000503548.1	chr4_1386758_+	-1963.20	-1958.90	-2017.10
CAediting_345048	ENST00000503548.1	chr4_1386768_+	-1960.00	-1958.90	-2017.10
CAediting_345049	ENST00000503548.1	chr4_1386782_+	-1958.90	-1958.90	-2017.10
CAediting_345050	ENST00000503548.1	chr4_1386787_+	-1959.50	-1958.90	-2017.10
CAediting_345051	ENST00000503548.1	chr4_1386792_+	-1958.20	-1958.90	-2017.10
CAediting_345052	ENST00000503548.1	chr4_1386797_+	-1958.20	-1958.90	-2017.10
CAediting_345053	ENST00000503548.1	chr4_1386818_+	-1961.10	-1958.90	-2017.10
CAediting_345054	ENST00000503548.1	chr4_1386830_+	-1958.50	-1958.90	-2017.10
CAediting_345055	ENST00000503548.1	chr4_1386835_+	-1961.30	-1958.90	-2017.10
CAediting_345056	ENST00000503548.1	chr4_1386859_+	-1958.90	-1958.90	-2017.10
CAediting_345057	ENST00000503548.1	chr4_1386865_+	-1961.70	-1958.90	-2017.10
CAediting_345058	ENST00000503548.1	chr4_1386867_+	-1962.60	-1958.90	-2017.10
CAediting_345059	ENST00000503548.1	chr4_1386873_+	-1963.00	-1958.90	-2017.10
CAediting_345060	ENST00000503548.1	chr4_1386947_+	-1965.50	-1958.90	-2017.10
CAediting_345061	ENST00000503548.1	chr4_1386954_+	-1959.10	-1958.90	-2017.10
CAediting_345062	ENST00000503548.1	chr4_1386993_+	-1961.20	-1958.90	-2017.10
CAediting_345063	ENST00000503548.1	chr4_1386999_+	-1958.40	-1958.90	-2017.10
CAediting_345064	ENST00000503548.1	chr4_1387006_+	-1960.90	-1958.90	-2017.10
CAediting_345065	ENST00000503548.1	chr4_1387098_+	-1958.80	-1958.90	-2017.10
CAediting_345066	ENST00000503548.1	chr4_1387099_+	-1958.80	-1958.90	-2017.10
CAediting_345067	ENST00000503548.1	chr4_1387104_+	-1961.70	-1958.90	-2017.10
CAediting_345068	ENST00000503548.1	chr4_1387121_+	-1958.20	-1958.90	-2017.10
CAediting_345069	ENST00000503548.1	chr4_1387128_+	-1961.30	-1958.90	-2017.10
CAediting_345070	ENST00000503548.1	chr4_1387142_+	-1959.10	-1958.90	-2017.10
CAediting_345071	ENST00000503548.1	chr4_1387152_+	-1958.20	-1958.90	-2017.10
CAediting_345072	ENST00000503548.1	chr4_1387157_+	-1958.90	-1958.90	-2017.10
CAediting_345073	ENST00000503548.1	chr4_1387158_+	-1959.60	-1958.90	-2017.10
CAediting_345074	ENST00000503548.1	chr4_1387164_+	-1962.30	-1958.90	-2017.10
CAediting_345075	ENST00000503548.1	chr4_1387178_+	-1962.40	-1958.90	-2017.10
CAediting_345076	ENST00000503548.1	chr4_1387204_+	-1961.50	-1958.90	-2017.10
CAediting_345077	ENST00000503548.1	chr4_1387207_+	-1958.90	-1958.90	-2017.10
CAediting_345078	ENST00000503548.1	chr4_1387217_+	-1959.30	-1958.90	-2017.10
CAediting_345079	ENST00000503548.1	chr4_1387227_+	-1959.10	-1958.90	-2017.10
CAediting_345080	ENST00000503548.1	chr4_1387233_+	-1959.70	-1958.90	-2017.10
CAediting_345081	ENST00000503548.1	chr4_1387243_+	-1959.50	-1958.90	-2017.10
CAediting_345082	ENST00000503548.1	chr4_1387252_+	-1961.40	-1958.90	-2017.10
CAediting_345083	ENST00000503548.1	chr4_1387261_+	-1959.00	-1958.90	-2017.10
CAediting_345084	ENST00000503548.1	chr4_1387275_+	-1959.20	-1958.90	-2017.10
CAediting_345085	ENST00000503548.1	chr4_1387323_+	-1958.50	-1958.90	-2017.10
CAediting_345086	ENST00000503548.1	chr4_1387350_+	-1960.70	-1958.90	-2017.10

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Relation with ADAR for UVSSA

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_345050	chr4_1386787_+	.	.	0.00151467030693902	0.285294754270644	.	.
LGG	CAediting_345051	chr4_1386792_+	.	.	.	.	0.00142814668327734	0.270817124119785
LGG	CAediting_345052	chr4_1386797_+	.	.	.	.	0.00776641053660467	0.217302151692441
THCA	CAediting_345052	chr4_1386797_+	.	.	.	.	0.0240887082930896	0.196287363167446

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Relation with cancer stages for UVSSA

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for UVSSA

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for UVSSA

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for UVSSA

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
UVSSA	C1833561	UV-Sensitive Syndrome	3	CTD_human;GENOMICS_ENGLAND;ORPHANET
UVSSA	C3553328	UV-SENSITIVE SYNDROME 3	3	GENOMICS_ENGLAND;UNIPROT

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene