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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: VPS18 (CAeditome ID:57617) |
Gene summary for VPS18 |
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Gene information | Gene symbol | VPS18 | Gene ID | 57617 |
Gene name | VPS18 core subunit of CORVET and HOPS complexes | |
Synonyms | PEP3 | |
Cytomap | 15q15.1 | |
Type of gene | protein-coding | |
Description | vacuolar protein sorting-associated protein 18 homologVPS18, CORVET/HOPS core subunithVPS18vacuolar protein sorting 18 homologvacuolar protein sorting protein 18 | |
Modification date | 20210518 | |
UniProtAcc | Q9P253 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
VPS18 | GO:0019905 | Vacuolar protein sorting-associated protein 18 homolog | 11382755 |
VPS18 | GO:0007032 | Vacuolar protein sorting-associated protein 18 homolog | 18799622 |
VPS18 | GO:0007040 | Vacuolar protein sorting-associated protein 18 homolog | 18799622 |
VPS18 | GO:2000300 | Vacuolar protein sorting-associated protein 18 homolog | 17027648 |
VPS18 | GO:0005764 | Vacuolar protein sorting-associated protein 18 homolog | 11382755 |
VPS18 | GO:0005764 | Vacuolar protein sorting-associated protein 18 homolog | 21802320 |
VPS18 | GO:0005770 | Vacuolar protein sorting-associated protein 18 homolog | 11382755 |
VPS18 | GO:0098978 | Vacuolar protein sorting-associated protein 18 homolog | 17027648 |
VPS18 | GO:0030897 | Vacuolar protein sorting-associated protein 18 homolog | 19109425 |
VPS18 | GO:0030897 | Vacuolar protein sorting-associated protein 18 homolog | 23901104 |
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RNA A-to-I events for VPS18 |
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CAediting_1029207(40896277, +), CAediting_1029208(40896311, +), CAediting_1029209(40896357, +), CAediting_1029210(40896549, +), CAediting_1029211(40896680, +), CAediting_1029212(40896690, +), CAediting_1029213(40896691, +), CAediting_1029214(40898708, +), CAediting_1029215(40901691, +), CAediting_1029216(40901786, +), CAediting_1029217(40903143, +), |
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RNA editing positional annotations for VPS18 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_1029207 | chr15_40896277_+ | intronic |
CAediting_1029208 | chr15_40896311_+ | intronic |
CAediting_1029209 | chr15_40896357_+ | intronic |
CAediting_1029210 | chr15_40896549_+ | intronic |
CAediting_1029211 | chr15_40896680_+ | intronic |
CAediting_1029212 | chr15_40896690_+ | intronic |
CAediting_1029213 | chr15_40896691_+ | intronic |
CAediting_1029214 | chr15_40898708_+ | exonic |
CAediting_1029215 | chr15_40901691_+ | intronic |
CAediting_1029216 | chr15_40901786_+ | intronic |
CAediting_1029217 | chr15_40903143_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_1029207 | chr15_40896277_+ | SINE | Alu | AluJr |
CAediting_1029208 | chr15_40896311_+ | SINE | Alu | AluJr |
CAediting_1029209 | chr15_40896357_+ | SINE | Alu | AluJr |
CAediting_1029210 | chr15_40896549_+ | SINE | Alu | AluSq2 |
CAediting_1029211 | chr15_40896680_+ | SINE | Alu | AluSq2 |
CAediting_1029212 | chr15_40896690_+ | SINE | Alu | AluSq2 |
CAediting_1029213 | chr15_40896691_+ | SINE | Alu | AluSq2 |
CAediting_1029214 | chr15_40898708_+ | SINE | Alu | AluJb |
CAediting_1029215 | chr15_40901691_+ | SINE | Alu | AluSx |
CAediting_1029216 | chr15_40901786_+ | SINE | Alu | AluSx |
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RNA A-to-I editing events in the alternative splicing sites for VPS18 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
ES | CAediting_1029209 | chr15_40896357_+ | 40896355:40896363 | 5SS | 1+0i | ATAGTGAGA | 1.69 | ATGGTGAGA | 7.23 |
MEX_1 | CAediting_1029209 | chr15_40896357_+ | 40896355:40896363 | 5SS | 1+0i | ATAGTGAGA | 1.69 | ATGGTGAGA | 7.23 |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for VPS18 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for VPS18 |
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The effects of the RNA editing to the miRNA binding sites for VPS18 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1368054 | chr19_46709310_- | ENSG00000104142.9 | ENST00000220509 | hsa-miR-320e | 40903739 | 40903745 | 7mer-m8 | 40903727 | 40903746 | 150 | -24.01 |
CAediting_86358 | chr1_109598906_+ | ENSG00000104142.9 | ENST00000220509 | hsa-miR-197-5p | 40903616 | 40903622 | 7mer-m8 | 40903603 | 40903623 | 150 | -23 |
CAediting_1054808 | chr15_66496985_- | ENSG00000104142.9 | ENST00000558855 | hsa-miR-4512 | 40899288 | 40899295 | 8mer-1a | 40899274 | 40899295 | 149 | -22.51 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1368054 | chr19_46709310_- | ENSG00000104142.9 | ENST00000220509 | hsa-miR-320e | 40903514 | 40903520 | 7mer-m8 | 40903505 | 40903521 | 142 | -13.61 |
CAediting_396018 | chr5_1062918_- | ENSG00000104142.9 | ENST00000558474 | hsa-miR-4635 | 40902818 | 40902824 | 7mer-m8 | 40902805 | 40902825 | 145 | -11.82 |
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The effects of the RNA editing to the stability of the RNA structures for VPS18 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for VPS18 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for VPS18 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for VPS18 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for VPS18 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for VPS18 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |