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Editing gene: CC2D2A (CAeditome ID:57545)

Gene summary for CC2D2A

Gene summary

Gene information	Gene symbol	CC2D2A
	Gene ID	57545
	Gene name	coiled-coil and C2 domain containing 2A
	Synonyms	COACH2\|JBTS9\|MKS6
	Cytomap	4p15.32
	Type of gene	protein-coding
	Description	coiled-coil and C2 domain-containing protein 2A
	Modification date	20210518
	UniProtAcc	Q9P2K1
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for CC2D2A

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000048342.14

RNA A-to-I editing events in Cancer.

CAediting_350441(15481231, +), CAediting_350442(15481235, +), CAediting_350443(15481241, +), CAediting_350444(15481253, +), CAediting_350445(15481270, +), CAediting_350446(15481276, +), CAediting_350447(15481294, +), CAediting_350448(15481302, +), CAediting_350449(15481322, +), CAediting_350450(15481332, +), CAediting_350451(15481333, +), CAediting_350452(15481338, +), CAediting_350453(15481368, +), CAediting_350454(15481391, +), CAediting_350455(15481431, +), CAediting_350456(15481432, +), CAediting_350457(15481468, +), CAediting_350458(15481486, +), CAediting_350459(15481490, +), CAediting_350460(15481499, +), CAediting_350461(15481501, +), CAediting_350462(15506890, +), CAediting_350463(15506958, +), CAediting_350464(15506963, +), CAediting_350465(15507006, +), CAediting_350466(15509403, +), CAediting_350467(15562777, +), CAediting_350468(15565742, +), CAediting_350469(15565743, +), CAediting_350470(15566752, +), CAediting_350471(15578719, +), CAediting_350472(15578743, +), CAediting_350473(15590502, +), CAediting_350474(15590811, +), CAediting_350475(15590823, +), CAediting_350476(15590849, +), CAediting_350477(15590854, +), CAediting_350478(15590866, +), CAediting_350479(15590925, +), CAediting_350480(15590930, +), CAediting_350481(15590962, +), CAediting_350482(15590963, +), CAediting_350483(15590980, +), CAediting_350484(15591002, +), CAediting_350485(15591300, +), CAediting_350486(15591319, +), CAediting_350487(15600723, +), CAediting_350488(15600914, +),

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RNA editing positional annotations for CC2D2A using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_350442	chr4_15481235_+	nonsynonymous SNV	ENST00000507954.4	c.A286G	p.T96A	D	.	N
CAediting_350442	chr4_15481235_+	nonsynonymous SNV	ENST00000515124.4	c.A286G	p.T96A	D	.	N
CAediting_350443	chr4_15481241_+	nonsynonymous SNV	ENST00000507954.4	c.A292G	p.T98A	D	.	N
CAediting_350443	chr4_15481241_+	nonsynonymous SNV	ENST00000515124.4	c.A292G	p.T98A	D	.	N
CAediting_350444	chr4_15481253_+	nonsynonymous SNV	ENST00000507954.4	c.A304G	p.N102D	D	.	N
CAediting_350444	chr4_15481253_+	nonsynonymous SNV	ENST00000515124.4	c.A304G	p.N102D	D	.	N

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_350441	chr4_15481231_+	exonic
CAediting_350442	chr4_15481235_+	exonic
CAediting_350443	chr4_15481241_+	exonic
CAediting_350444	chr4_15481253_+	exonic
CAediting_350445	chr4_15481270_+	exonic
CAediting_350446	chr4_15481276_+	exonic
CAediting_350447	chr4_15481294_+	ncRNA_intronic
CAediting_350448	chr4_15481302_+	ncRNA_intronic
CAediting_350449	chr4_15481322_+	ncRNA_intronic
CAediting_350450	chr4_15481332_+	ncRNA_intronic
CAediting_350451	chr4_15481333_+	ncRNA_intronic
CAediting_350452	chr4_15481338_+	ncRNA_intronic
CAediting_350453	chr4_15481368_+	ncRNA_intronic
CAediting_350454	chr4_15481391_+	ncRNA_intronic
CAediting_350455	chr4_15481431_+	ncRNA_intronic
CAediting_350456	chr4_15481432_+	ncRNA_intronic
CAediting_350457	chr4_15481468_+	ncRNA_intronic
CAediting_350458	chr4_15481486_+	ncRNA_intronic
CAediting_350459	chr4_15481490_+	ncRNA_intronic
CAediting_350460	chr4_15481499_+	ncRNA_intronic
CAediting_350461	chr4_15481501_+	ncRNA_intronic
CAediting_350462	chr4_15506890_+	ncRNA_intronic
CAediting_350463	chr4_15506958_+	ncRNA_intronic
CAediting_350464	chr4_15506963_+	ncRNA_intronic
CAediting_350465	chr4_15507006_+	ncRNA_intronic
CAediting_350466	chr4_15509403_+	ncRNA_intronic
CAediting_350467	chr4_15562777_+	intronic
CAediting_350468	chr4_15565742_+	intronic
CAediting_350469	chr4_15565743_+	intronic
CAediting_350470	chr4_15566752_+	intronic
CAediting_350471	chr4_15578719_+	intronic
CAediting_350472	chr4_15578743_+	intronic
CAediting_350473	chr4_15590502_+	ncRNA_intronic
CAediting_350474	chr4_15590811_+	ncRNA_intronic
CAediting_350475	chr4_15590823_+	ncRNA_intronic
CAediting_350476	chr4_15590849_+	ncRNA_intronic
CAediting_350477	chr4_15590854_+	ncRNA_intronic
CAediting_350478	chr4_15590866_+	ncRNA_intronic
CAediting_350479	chr4_15590925_+	ncRNA_intronic
CAediting_350480	chr4_15590930_+	ncRNA_intronic
CAediting_350481	chr4_15590962_+	ncRNA_intronic
CAediting_350482	chr4_15590963_+	ncRNA_intronic
CAediting_350483	chr4_15590980_+	ncRNA_intronic
CAediting_350484	chr4_15591002_+	ncRNA_intronic
CAediting_350485	chr4_15591300_+	ncRNA_intronic
CAediting_350486	chr4_15591319_+	ncRNA_intronic
CAediting_350487	chr4_15600723_+	ncRNA_intronic
CAediting_350488	chr4_15600914_+	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_350441	chr4_15481231_+	SINE	Alu	AluSx
CAediting_350442	chr4_15481235_+	SINE	Alu	AluSx
CAediting_350443	chr4_15481241_+	SINE	Alu	AluSx
CAediting_350444	chr4_15481253_+	SINE	Alu	AluSx
CAediting_350445	chr4_15481270_+	SINE	Alu	AluSx
CAediting_350446	chr4_15481276_+	SINE	Alu	AluSx
CAediting_350447	chr4_15481294_+	SINE	Alu	AluSx
CAediting_350448	chr4_15481302_+	SINE	Alu	AluSx
CAediting_350449	chr4_15481322_+	SINE	Alu	AluSx
CAediting_350450	chr4_15481332_+	SINE	Alu	AluSx
CAediting_350451	chr4_15481333_+	SINE	Alu	AluSx
CAediting_350452	chr4_15481338_+	SINE	Alu	AluSx
CAediting_350453	chr4_15481368_+	SINE	Alu	AluSx
CAediting_350454	chr4_15481391_+	SINE	Alu	AluSx
CAediting_350455	chr4_15481431_+	SINE	Alu	AluSx
CAediting_350456	chr4_15481432_+	SINE	Alu	AluSx
CAediting_350457	chr4_15481468_+	SINE	Alu	AluSx
CAediting_350458	chr4_15481486_+	SINE	Alu	AluSx
CAediting_350459	chr4_15481490_+	SINE	Alu	AluSx
CAediting_350460	chr4_15481499_+	SINE	Alu	AluSx
CAediting_350461	chr4_15481501_+	SINE	Alu	AluSx
CAediting_350462	chr4_15506890_+	SINE	Alu	AluSx3
CAediting_350463	chr4_15506958_+	SINE	Alu	AluSx3
CAediting_350464	chr4_15506963_+	SINE	Alu	AluSx3
CAediting_350465	chr4_15507006_+	SINE	Alu	AluSx3
CAediting_350466	chr4_15509403_+	SINE	Alu	AluSx1
CAediting_350467	chr4_15562777_+	SINE	MIR	MIRb
CAediting_350468	chr4_15565742_+	SINE	Alu	AluJo
CAediting_350469	chr4_15565743_+	SINE	Alu	AluJo
CAediting_350470	chr4_15566752_+	SINE	Alu	AluJb
CAediting_350471	chr4_15578719_+	SINE	Alu	AluJb
CAediting_350472	chr4_15578743_+	SINE	Alu	AluJb
CAediting_350473	chr4_15590502_+	SINE	Alu	AluSx
CAediting_350474	chr4_15590811_+	SINE	Alu	AluSz
CAediting_350475	chr4_15590823_+	SINE	Alu	AluSz
CAediting_350476	chr4_15590849_+	SINE	Alu	AluSz
CAediting_350477	chr4_15590854_+	SINE	Alu	AluSz
CAediting_350478	chr4_15590866_+	SINE	Alu	AluSz
CAediting_350479	chr4_15590925_+	SINE	Alu	AluSz
CAediting_350480	chr4_15590930_+	SINE	Alu	AluSz
CAediting_350481	chr4_15590962_+	SINE	Alu	AluSz
CAediting_350482	chr4_15590963_+	SINE	Alu	AluSz
CAediting_350483	chr4_15590980_+	SINE	Alu	AluSz
CAediting_350484	chr4_15591002_+	SINE	Alu	AluSz
CAediting_350485	chr4_15591300_+	SINE	Alu	AluSp
CAediting_350486	chr4_15591319_+	SINE	Alu	AluSp
CAediting_350487	chr4_15600723_+	SINE	Alu	AluJb
CAediting_350488	chr4_15600914_+	SINE	Alu	AluJb

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RNA A-to-I editing events in the alternative splicing sites for CC2D2A

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000048342.14.CC2D2A.

Correlation between RNA A-to-I editing and PSI for ENSG00000048342.14.CC2D2A.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CC2D2A

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CC2D2A

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for CC2D2A

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_350450	chr4_15481332_+	ENSG00000048342.14	ENST00000515124	hsa-miR-6873-3p	15481327	15481332	6mer	15481311	15481333	141.00	-11.44
CAediting_350450	chr4_15481332_+	ENSG00000048342.14	ENST00000515124	hsa-miR-6895-3p	15481327	15481333	7mer-m8	15481313	15481334	150.00	-15.95
CAediting_350451	chr4_15481333_+	ENSG00000048342.14	ENST00000515124	hsa-miR-6815-3p	15481328	15481334	7mer-m8	15481314	15481335	147.00	-16.85
CAediting_350451	chr4_15481333_+	ENSG00000048342.14	ENST00000515124	hsa-miR-942-5p	15481327	15481332	6mer	15481312	15481333	156.00	-16.88
CAediting_350452	chr4_15481338_+	ENSG00000048342.14	ENST00000515124	hsa-miR-483-5p	15481334	15481340	7mer-m8	15481320	15481341	140.00	-14.01
CAediting_350454	chr4_15481391_+	ENSG00000048342.14	ENST00000515124	hsa-miR-8052	15481389	15481395	7mer-1a	15481377	15481395	143.00	-24.25
CAediting_350455	chr4_15481431_+	ENSG00000048342.14	ENST00000515124	hsa-miR-9900	15481429	15481435	7mer-m8	15481417	15481436	151.00	-16.39
CAediting_350456	chr4_15481432_+	ENSG00000048342.14	ENST00000515124	hsa-miR-3155a	15481429	15481435	7mer-m8	15481415	15481436	149.00	-22.89
CAediting_350456	chr4_15481432_+	ENSG00000048342.14	ENST00000515124	hsa-miR-3155b	15481429	15481435	7mer-m8	15481418	15481436	149.00	-22.89
CAediting_350456	chr4_15481432_+	ENSG00000048342.14	ENST00000515124	hsa-miR-484	15481429	15481435	7mer-m8	15481415	15481436	152.00	-19.04
CAediting_350457	chr4_15481468_+	ENSG00000048342.14	ENST00000515124	hsa-miR-371b-3p	15481466	15481472	7mer-m8	15481451	15481473	147.00	-18.80
CAediting_350461	chr4_15481501_+	ENSG00000048342.14	ENST00000515124	hsa-miR-1915-5p	15481495	15481500	6mer	15481480	15481501	144.00	-28.11
CAediting_350461	chr4_15481501_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4312	15481496	15481501	6mer	15481485	15481502	140.00	-20.88

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_350454	chr4_15481391_+	ENSG00000048342.14	ENST00000515124	hsa-miR-10399-5p	15481385	15481391	7mer-m8	15481371	15481392	148	-11.23
CAediting_350450	chr4_15481332_+	ENSG00000048342.14	ENST00000515124	hsa-miR-193b-5p	15481330	15481337	8mer-1a	15481316	15481337	141	-13.71
CAediting_350451	chr4_15481333_+	ENSG00000048342.14	ENST00000515124	hsa-miR-193b-5p	15481330	15481337	8mer-1a	15481316	15481337	141	-13.71
CAediting_350451	chr4_15481333_+	ENSG00000048342.14	ENST00000515124	hsa-miR-3170	15481331	15481337	7mer-m8	15481316	15481338	141	-13.81
CAediting_350452	chr4_15481338_+	ENSG00000048342.14	ENST00000515124	hsa-miR-3170	15481331	15481337	7mer-m8	15481316	15481338	141	-13.81
CAediting_350461	chr4_15481501_+	ENSG00000048342.14	ENST00000515124	hsa-miR-3198	15481499	15481505	7mer-m8	15481485	15481506	147	-16.34
CAediting_350461	chr4_15481501_+	ENSG00000048342.14	ENST00000515124	hsa-miR-3198	15481499	15481505	7mer-m8	15481485	15481506	147	-16.34
CAediting_350459	chr4_15481490_+	ENSG00000048342.14	ENST00000515124	hsa-miR-367-5p	15481487	15481494	8mer-1a	15481475	15481494	145	-11.45
CAediting_350461	chr4_15481501_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4294	15481498	15481505	8mer-1a	15481489	15481505	140	-13.12
CAediting_350461	chr4_15481501_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4309	15481499	15481505	7mer-m8	15481489	15481506	147	-13.35
CAediting_350460	chr4_15481499_+	ENSG00000048342.14	ENST00000515124	hsa-miR-431-5p	15481495	15481501	7mer-m8	15481482	15481502	140	-13.22
CAediting_350461	chr4_15481501_+	ENSG00000048342.14	ENST00000515124	hsa-miR-431-5p	15481495	15481501	7mer-m8	15481482	15481502	140	-13.22
CAediting_350459	chr4_15481490_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4423-5p	15481485	15481492	8mer-1a	15481471	15481492	140	-12.05
CAediting_350448	chr4_15481302_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4680-5p	15481300	15481306	7mer-1a	15481286	15481306	146	-20.16
CAediting_350458	chr4_15481486_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4774-3p	15481484	15481490	7mer-m8	15481471	15481491	141	-12.66
CAediting_350459	chr4_15481490_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4774-3p	15481484	15481490	7mer-m8	15481471	15481491	141	-12.66
CAediting_350449	chr4_15481322_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4781-3p	15481319	15481325	7mer-m8	15481303	15481326	142	-11.02
CAediting_350453	chr4_15481368_+	ENSG00000048342.14	ENST00000515124	hsa-miR-4794	15481362	15481368	7mer-m8	15481348	15481369	140	-12.3
CAediting_350455	chr4_15481431_+	ENSG00000048342.14	ENST00000515124	hsa-miR-498-5p	15481425	15481431	7mer-m8	15481410	15481432	142	-13.53
CAediting_350456	chr4_15481432_+	ENSG00000048342.14	ENST00000515124	hsa-miR-498-5p	15481425	15481431	7mer-m8	15481410	15481432	142	-13.53
CAediting_350454	chr4_15481391_+	ENSG00000048342.14	ENST00000515124	hsa-miR-5089-5p	15481389	15481395	7mer-m8	15481376	15481396	147	-14.68
CAediting_350454	chr4_15481391_+	ENSG00000048342.14	ENST00000515124	hsa-miR-6504-3p	15481385	15481391	7mer-m8	15481371	15481392	148	-15.29
CAediting_350453	chr4_15481368_+	ENSG00000048342.14	ENST00000515124	hsa-miR-664a-5p	15481362	15481368	7mer-m8	15481346	15481369	141	-13.79
CAediting_350451	chr4_15481333_+	ENSG00000048342.14	ENST00000515124	hsa-miR-6855-5p	15481331	15481337	7mer-m8	15481314	15481338	145	-18.04
CAediting_350452	chr4_15481338_+	ENSG00000048342.14	ENST00000515124	hsa-miR-6855-5p	15481331	15481337	7mer-m8	15481314	15481338	145	-18.04
CAediting_350452	chr4_15481338_+	ENSG00000048342.14	ENST00000515124	hsa-miR-6890-5p	15481332	15481338	7mer-m8	15481319	15481339	140	-13.25
CAediting_350459	chr4_15481490_+	ENSG00000048342.14	ENST00000515124	hsa-miR-744-3p	15481486	15481492	7mer-m8	15481474	15481493	141	-14.62

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_468389	chr6_31355314_-	ENSG00000048342.14	ENST00000515124	hsa-miR-6891-5p	15481541	15481547	7mer-m8	15481530	15481548	140	-20.22

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_846604	chr11_93733708_-	ENSG00000048342.14	ENST00000515124	hsa-miR-1304-3p	15481679	15481685	7mer-m8	15481665	15481686	145	-15.41

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CC2D2A

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000438599.5	protein_coding
ENST00000503658.1	protein_coding
ENST00000507954.4	protein_coding
ENST00000511544.4	protein_coding
ENST00000515124.4	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_350441	ENST00000438599.5	chr4_15481231_+	-486.60	-487.30	-505.80
CAediting_350442	ENST00000438599.5	chr4_15481235_+	-488.20	-487.30	-505.80
CAediting_350443	ENST00000438599.5	chr4_15481241_+	-491.10	-487.30	-505.80
CAediting_350444	ENST00000438599.5	chr4_15481253_+	-490.50	-487.30	-505.80
CAediting_350445	ENST00000438599.5	chr4_15481270_+	-490.90	-487.30	-505.80
CAediting_350446	ENST00000438599.5	chr4_15481276_+	-490.70	-487.30	-505.80
CAediting_350447	ENST00000438599.5	chr4_15481294_+	-487.70	-487.30	-505.80
CAediting_350448	ENST00000438599.5	chr4_15481302_+	-488.80	-487.30	-505.80
CAediting_350449	ENST00000438599.5	chr4_15481322_+	-488.20	-487.30	-505.80
CAediting_350450	ENST00000438599.5	chr4_15481332_+	-488.40	-487.30	-505.80
CAediting_350451	ENST00000438599.5	chr4_15481333_+	-490.60	-487.30	-505.80
CAediting_350452	ENST00000438599.5	chr4_15481338_+	-487.30	-487.30	-505.80
CAediting_350453	ENST00000438599.5	chr4_15481368_+	-486.60	-487.30	-505.80
CAediting_350454	ENST00000438599.5	chr4_15481391_+	-487.30	-487.30	-505.80
CAediting_350455	ENST00000438599.5	chr4_15481431_+	-487.30	-487.30	-505.80
CAediting_350456	ENST00000438599.5	chr4_15481432_+	-491.00	-487.30	-505.80
CAediting_350457	ENST00000438599.5	chr4_15481468_+	-486.20	-487.30	-505.80
CAediting_350458	ENST00000438599.5	chr4_15481486_+	-486.90	-487.30	-505.80
CAediting_350459	ENST00000438599.5	chr4_15481490_+	-487.30	-487.30	-505.80
CAediting_350460	ENST00000438599.5	chr4_15481499_+	-487.20	-487.30	-505.80
CAediting_350461	ENST00000438599.5	chr4_15481501_+	-489.90	-487.30	-505.80
CAediting_350441	ENST00000503658.1	chr4_15481231_+	-177.60	-178.30	-187.10
CAediting_350442	ENST00000503658.1	chr4_15481235_+	-178.30	-178.30	-187.10
CAediting_350443	ENST00000503658.1	chr4_15481241_+	-178.50	-178.30	-187.10
CAediting_350444	ENST00000503658.1	chr4_15481253_+	-178.30	-178.30	-187.10
CAediting_350445	ENST00000503658.1	chr4_15481270_+	-178.60	-178.30	-187.10
CAediting_350446	ENST00000503658.1	chr4_15481276_+	-179.00	-178.30	-187.10
CAediting_350447	ENST00000503658.1	chr4_15481294_+	-179.50	-178.30	-187.10
CAediting_350448	ENST00000503658.1	chr4_15481302_+	-179.70	-178.30	-187.10
CAediting_350449	ENST00000503658.1	chr4_15481322_+	-178.30	-178.30	-187.10
CAediting_350450	ENST00000503658.1	chr4_15481332_+	-179.60	-178.30	-187.10
CAediting_350451	ENST00000503658.1	chr4_15481333_+	-178.30	-178.30	-187.10
CAediting_350452	ENST00000503658.1	chr4_15481338_+	-179.60	-178.30	-187.10
CAediting_350453	ENST00000503658.1	chr4_15481368_+	-177.60	-178.30	-187.10
CAediting_350441	ENST00000507954.4	chr4_15481231_+	-150.20	-149.20	-157.10
CAediting_350442	ENST00000507954.4	chr4_15481235_+	-150.00	-149.20	-157.10
CAediting_350443	ENST00000507954.4	chr4_15481241_+	-152.70	-149.20	-157.10
CAediting_350444	ENST00000507954.4	chr4_15481253_+	-152.40	-149.20	-157.10
CAediting_350445	ENST00000507954.4	chr4_15481270_+	-150.50	-149.20	-157.10
CAediting_350446	ENST00000507954.4	chr4_15481276_+	-151.00	-149.20	-157.10
CAediting_350441	ENST00000511544.4	chr4_15481231_+	-469.20	-469.90	-486.20
CAediting_350442	ENST00000511544.4	chr4_15481235_+	-470.10	-469.90	-486.20
CAediting_350443	ENST00000511544.4	chr4_15481241_+	-474.10	-469.90	-486.20
CAediting_350444	ENST00000511544.4	chr4_15481253_+	-471.40	-469.90	-486.20
CAediting_350445	ENST00000511544.4	chr4_15481270_+	-471.20	-469.90	-486.20
CAediting_350446	ENST00000511544.4	chr4_15481276_+	-469.60	-469.90	-486.20
CAediting_350447	ENST00000511544.4	chr4_15481294_+	-472.50	-469.90	-486.20
CAediting_350448	ENST00000511544.4	chr4_15481302_+	-469.70	-469.90	-486.20
CAediting_350449	ENST00000511544.4	chr4_15481322_+	-470.40	-469.90	-486.20
CAediting_350450	ENST00000511544.4	chr4_15481332_+	-471.20	-469.90	-486.20
CAediting_350451	ENST00000511544.4	chr4_15481333_+	-472.50	-469.90	-486.20
CAediting_350452	ENST00000511544.4	chr4_15481338_+	-469.90	-469.90	-486.20
CAediting_350453	ENST00000511544.4	chr4_15481368_+	-469.20	-469.90	-486.20
CAediting_350454	ENST00000511544.4	chr4_15481391_+	-469.90	-469.90	-486.20
CAediting_350455	ENST00000511544.4	chr4_15481431_+	-469.90	-469.90	-486.20
CAediting_350456	ENST00000511544.4	chr4_15481432_+	-473.60	-469.90	-486.20
CAediting_350457	ENST00000511544.4	chr4_15481468_+	-468.80	-469.90	-486.20
CAediting_350458	ENST00000511544.4	chr4_15481486_+	-468.60	-469.90	-486.20
CAediting_350459	ENST00000511544.4	chr4_15481490_+	-469.90	-469.90	-486.20
CAediting_350460	ENST00000511544.4	chr4_15481499_+	-469.70	-469.90	-486.20
CAediting_350461	ENST00000511544.4	chr4_15481501_+	-471.30	-469.90	-486.20
CAediting_350441	ENST00000515124.4	chr4_15481231_+	-423.60	-423.90	-438.50
CAediting_350442	ENST00000515124.4	chr4_15481235_+	-424.50	-423.90	-438.50
CAediting_350443	ENST00000515124.4	chr4_15481241_+	-428.80	-423.90	-438.50
CAediting_350444	ENST00000515124.4	chr4_15481253_+	-426.30	-423.90	-438.50
CAediting_350445	ENST00000515124.4	chr4_15481270_+	-424.10	-423.90	-438.50
CAediting_350446	ENST00000515124.4	chr4_15481276_+	-424.50	-423.90	-438.50
CAediting_350447	ENST00000515124.4	chr4_15481294_+	-424.00	-423.90	-438.50
CAediting_350448	ENST00000515124.4	chr4_15481302_+	-423.20	-423.90	-438.50
CAediting_350449	ENST00000515124.4	chr4_15481322_+	-425.90	-423.90	-438.50
CAediting_350450	ENST00000515124.4	chr4_15481332_+	-425.20	-423.90	-438.50
CAediting_350451	ENST00000515124.4	chr4_15481333_+	-428.00	-423.90	-438.50
CAediting_350452	ENST00000515124.4	chr4_15481338_+	-424.20	-423.90	-438.50
CAediting_350453	ENST00000515124.4	chr4_15481368_+	-423.20	-423.90	-438.50
CAediting_350454	ENST00000515124.4	chr4_15481391_+	-423.90	-423.90	-438.50
CAediting_350455	ENST00000515124.4	chr4_15481431_+	-423.90	-423.90	-438.50
CAediting_350456	ENST00000515124.4	chr4_15481432_+	-427.60	-423.90	-438.50
CAediting_350457	ENST00000515124.4	chr4_15481468_+	-422.80	-423.90	-438.50
CAediting_350458	ENST00000515124.4	chr4_15481486_+	-422.60	-423.90	-438.50
CAediting_350459	ENST00000515124.4	chr4_15481490_+	-423.90	-423.90	-438.50
CAediting_350460	ENST00000515124.4	chr4_15481499_+	-422.90	-423.90	-438.50
CAediting_350461	ENST00000515124.4	chr4_15481501_+	-425.30	-423.90	-438.50

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Relation with ADAR for CC2D2A

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for CC2D2A

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for CC2D2A

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for CC2D2A

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for CC2D2A

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
CC2D2A	C2676788	JOUBERT SYNDROME 9 (disorder)	11	CTD_human;GENOMICS_ENGLAND;UNIPROT
CC2D2A	C2676790	MECKEL SYNDROME, TYPE 6 (disorder)	9	CTD_human;GENOMICS_ENGLAND;UNIPROT
CC2D2A	C1857662	COACH syndrome	5	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
CC2D2A	C0009714	Hepatic Fibrosis, Congenital	2	GENOMICS_ENGLAND
CC2D2A	C0265215	Meckel-Gruber syndrome	2	ORPHANET
CC2D2A	C0152427	Polydactyly	1	GENOMICS_ENGLAND
CC2D2A	C0238198	Gastrointestinal Stromal Tumors	1	CTD_human
CC2D2A	C3179349	Gastrointestinal Stromal Sarcoma	1	CTD_human
CC2D2A	C3714506	Meckel syndrome type 1	1	GENOMICS_ENGLAND

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene