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Editing gene: LRRC47 (CAeditome ID:57470)

Gene summary for LRRC47

Gene summary

Gene information	Gene symbol	LRRC47
	Gene ID	57470
	Gene name	leucine rich repeat containing 47
	Synonyms	-
	Cytomap	1p36.32
	Type of gene	protein-coding
	Description	leucine-rich repeat-containing protein 47
	Modification date	20210518
	UniProtAcc	Q8N1G4
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene

GO ID

GO term

PubMed ID

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RNA A-to-I events for LRRC47

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000130764.8

RNA A-to-I editing events in Cancer.

CAediting_4048(3780493, -), CAediting_4049(3780712, -), CAediting_4050(3780716, -), CAediting_4051(3780748, -), CAediting_4052(3780759, -), CAediting_4053(3780810, -), CAediting_4054(3780828, -), CAediting_4055(3780832, -), CAediting_4056(3780864, -), CAediting_4057(3780876, -), CAediting_4058(3780914, -), CAediting_4059(3781727, -), CAediting_4060(3781737, -), CAediting_4061(3781759, -), CAediting_4062(3781768, -), CAediting_4063(3781810, -), CAediting_4064(3781814, -), CAediting_4065(3781857, -), CAediting_4066(3781919, -), CAediting_4067(3781924, -), CAediting_4068(3782343, -), CAediting_4069(3783175, -), CAediting_4070(3784721, -), CAediting_4071(3784751, -), CAediting_4072(3784752, -), CAediting_4073(3784873, -), CAediting_4074(3784878, -), CAediting_4075(3784951, -), CAediting_4076(3785873, -), CAediting_4077(3785883, -), CAediting_4078(3785900, -), CAediting_4079(3785917, -), CAediting_4080(3785930, -), CAediting_4081(3785937, -), CAediting_4082(3785942, -), CAediting_4083(3785959, -), CAediting_4084(3785972, -), CAediting_4085(3785975, -), CAediting_4086(3785985, -), CAediting_4087(3785991, -), CAediting_4088(3785998, -), CAediting_4089(3786002, -), CAediting_4090(3786017, -), CAediting_4091(3786034, -), CAediting_4092(3786037, -), CAediting_4093(3786038, -), CAediting_4094(3786039, -), CAediting_4095(3786040, -), CAediting_4096(3786043, -), CAediting_4097(3786063, -), CAediting_4098(3786083, -), CAediting_4099(3786086, -), CAediting_4100(3786097, -), CAediting_4101(3786102, -), CAediting_4102(3786107, -), CAediting_4103(3786129, -), CAediting_4104(3786142, -), CAediting_4105(3786143, -), CAediting_4106(3786198, -), CAediting_4107(3786209, -), CAediting_4108(3786241, -), CAediting_4109(3786254, -), CAediting_4110(3786277, -), CAediting_4111(3786280, -), CAediting_4112(3786306, -), CAediting_4113(3786315, -), CAediting_4114(3786318, -), CAediting_4115(3786325, -), CAediting_4116(3786328, -), CAediting_4117(3786368, -), CAediting_4118(3786376, -), CAediting_4119(3786378, -), CAediting_4120(3786388, -), CAediting_4121(3786413, -), CAediting_4122(3786418, -), CAediting_4123(3786464, -), CAediting_4124(3786496, -),

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RNA editing positional annotations for LRRC47 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_4048	chr1_3780493_-	UTR3
CAediting_4049	chr1_3780712_-	UTR3
CAediting_4050	chr1_3780716_-	UTR3
CAediting_4051	chr1_3780748_-	UTR3
CAediting_4052	chr1_3780759_-	UTR3
CAediting_4053	chr1_3780810_-	UTR3
CAediting_4054	chr1_3780828_-	UTR3
CAediting_4055	chr1_3780832_-	UTR3
CAediting_4056	chr1_3780864_-	UTR3
CAediting_4057	chr1_3780876_-	UTR3
CAediting_4058	chr1_3780914_-	UTR3
CAediting_4059	chr1_3781727_-	ncRNA_intronic
CAediting_4060	chr1_3781737_-	ncRNA_intronic
CAediting_4061	chr1_3781759_-	ncRNA_intronic
CAediting_4062	chr1_3781768_-	ncRNA_intronic
CAediting_4063	chr1_3781810_-	ncRNA_intronic
CAediting_4064	chr1_3781814_-	ncRNA_intronic
CAediting_4065	chr1_3781857_-	ncRNA_intronic
CAediting_4066	chr1_3781919_-	ncRNA_intronic
CAediting_4067	chr1_3781924_-	ncRNA_intronic
CAediting_4068	chr1_3782343_-	ncRNA_intronic
CAediting_4069	chr1_3783175_-	ncRNA_intronic
CAediting_4070	chr1_3784721_-	intronic
CAediting_4071	chr1_3784751_-	intronic
CAediting_4072	chr1_3784752_-	intronic
CAediting_4073	chr1_3784873_-	intronic
CAediting_4074	chr1_3784878_-	intronic
CAediting_4075	chr1_3784951_-	intronic
CAediting_4076	chr1_3785873_-	intronic
CAediting_4077	chr1_3785883_-	intronic
CAediting_4078	chr1_3785900_-	intronic
CAediting_4079	chr1_3785917_-	intronic
CAediting_4080	chr1_3785930_-	intronic
CAediting_4081	chr1_3785937_-	intronic
CAediting_4082	chr1_3785942_-	intronic
CAediting_4083	chr1_3785959_-	intronic
CAediting_4084	chr1_3785972_-	intronic
CAediting_4085	chr1_3785975_-	intronic
CAediting_4086	chr1_3785985_-	intronic
CAediting_4087	chr1_3785991_-	intronic
CAediting_4088	chr1_3785998_-	intronic
CAediting_4089	chr1_3786002_-	intronic
CAediting_4090	chr1_3786017_-	intronic
CAediting_4091	chr1_3786034_-	intronic
CAediting_4092	chr1_3786037_-	intronic
CAediting_4093	chr1_3786038_-	intronic
CAediting_4094	chr1_3786039_-	intronic
CAediting_4095	chr1_3786040_-	intronic
CAediting_4096	chr1_3786043_-	intronic
CAediting_4097	chr1_3786063_-	intronic
CAediting_4098	chr1_3786083_-	intronic
CAediting_4099	chr1_3786086_-	intronic
CAediting_4100	chr1_3786097_-	intronic
CAediting_4101	chr1_3786102_-	intronic
CAediting_4102	chr1_3786107_-	intronic
CAediting_4103	chr1_3786129_-	intronic
CAediting_4104	chr1_3786142_-	intronic
CAediting_4105	chr1_3786143_-	intronic
CAediting_4106	chr1_3786198_-	intronic
CAediting_4107	chr1_3786209_-	intronic
CAediting_4108	chr1_3786241_-	intronic
CAediting_4109	chr1_3786254_-	intronic
CAediting_4110	chr1_3786277_-	intronic
CAediting_4111	chr1_3786280_-	intronic
CAediting_4112	chr1_3786306_-	intronic
CAediting_4113	chr1_3786315_-	intronic
CAediting_4114	chr1_3786318_-	intronic
CAediting_4115	chr1_3786325_-	intronic
CAediting_4116	chr1_3786328_-	intronic
CAediting_4117	chr1_3786368_-	intronic
CAediting_4118	chr1_3786376_-	intronic
CAediting_4119	chr1_3786378_-	intronic
CAediting_4120	chr1_3786388_-	intronic
CAediting_4121	chr1_3786413_-	intronic
CAediting_4122	chr1_3786418_-	intronic
CAediting_4123	chr1_3786464_-	intronic
CAediting_4124	chr1_3786496_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_4049	chr1_3780712_-	SINE	Alu	AluSc
CAediting_4050	chr1_3780716_-	SINE	Alu	AluSc
CAediting_4051	chr1_3780748_-	SINE	Alu	AluSc
CAediting_4052	chr1_3780759_-	SINE	Alu	AluSc
CAediting_4053	chr1_3780810_-	SINE	Alu	AluSc
CAediting_4054	chr1_3780828_-	SINE	Alu	AluSc
CAediting_4055	chr1_3780832_-	SINE	Alu	AluSc
CAediting_4056	chr1_3780864_-	SINE	Alu	AluSc
CAediting_4057	chr1_3780876_-	SINE	Alu	AluSc
CAediting_4058	chr1_3780914_-	SINE	Alu	AluSc
CAediting_4059	chr1_3781727_-	SINE	Alu	AluJo
CAediting_4060	chr1_3781737_-	SINE	Alu	AluJo
CAediting_4061	chr1_3781759_-	SINE	Alu	AluJo
CAediting_4062	chr1_3781768_-	SINE	Alu	AluJo
CAediting_4063	chr1_3781810_-	SINE	Alu	AluJo
CAediting_4064	chr1_3781814_-	SINE	Alu	AluJo
CAediting_4065	chr1_3781857_-	SINE	Alu	AluJo
CAediting_4066	chr1_3781919_-	SINE	Alu	AluJo
CAediting_4067	chr1_3781924_-	SINE	Alu	AluJo
CAediting_4068	chr1_3782343_-	SINE	Alu	AluSp
CAediting_4069	chr1_3783175_-	SINE	Alu	AluSq2
CAediting_4070	chr1_3784721_-	SINE	Alu	AluSp
CAediting_4071	chr1_3784751_-	SINE	Alu	AluSp
CAediting_4072	chr1_3784752_-	SINE	Alu	AluSp
CAediting_4073	chr1_3784873_-	SINE	Alu	AluSp
CAediting_4074	chr1_3784878_-	SINE	Alu	AluSp
CAediting_4075	chr1_3784951_-	SINE	Alu	AluSp
CAediting_4076	chr1_3785873_-	SINE	Alu	AluSx1
CAediting_4077	chr1_3785883_-	SINE	Alu	AluSx1
CAediting_4078	chr1_3785900_-	SINE	Alu	AluSx1
CAediting_4079	chr1_3785917_-	SINE	Alu	AluSx1
CAediting_4080	chr1_3785930_-	SINE	Alu	AluSx1
CAediting_4081	chr1_3785937_-	SINE	Alu	AluSx1
CAediting_4082	chr1_3785942_-	SINE	Alu	AluSx1
CAediting_4083	chr1_3785959_-	SINE	Alu	AluSx1
CAediting_4084	chr1_3785972_-	SINE	Alu	AluSx1
CAediting_4085	chr1_3785975_-	SINE	Alu	AluSx1
CAediting_4086	chr1_3785985_-	SINE	Alu	AluSx1
CAediting_4087	chr1_3785991_-	SINE	Alu	AluSx1
CAediting_4088	chr1_3785998_-	SINE	Alu	AluSx1
CAediting_4089	chr1_3786002_-	SINE	Alu	AluSx1
CAediting_4090	chr1_3786017_-	SINE	Alu	AluSx1
CAediting_4091	chr1_3786034_-	SINE	Alu	AluSx1
CAediting_4092	chr1_3786037_-	SINE	Alu	AluSx1
CAediting_4093	chr1_3786038_-	SINE	Alu	AluSx1
CAediting_4094	chr1_3786039_-	SINE	Alu	AluSx1
CAediting_4095	chr1_3786040_-	SINE	Alu	AluSx1
CAediting_4096	chr1_3786043_-	SINE	Alu	AluSx1
CAediting_4097	chr1_3786063_-	SINE	Alu	AluSx1
CAediting_4098	chr1_3786083_-	SINE	Alu	AluSx1
CAediting_4099	chr1_3786086_-	SINE	Alu	AluSx1
CAediting_4100	chr1_3786097_-	SINE	Alu	AluSx1
CAediting_4101	chr1_3786102_-	SINE	Alu	AluSx1
CAediting_4102	chr1_3786107_-	SINE	Alu	AluSx1
CAediting_4103	chr1_3786129_-	SINE	Alu	AluSx1
CAediting_4104	chr1_3786142_-	SINE	Alu	AluSx1
CAediting_4105	chr1_3786143_-	SINE	Alu	AluSx1
CAediting_4108	chr1_3786241_-	SINE	Alu	AluSz
CAediting_4109	chr1_3786254_-	SINE	Alu	AluSz
CAediting_4110	chr1_3786277_-	SINE	Alu	AluSz
CAediting_4111	chr1_3786280_-	SINE	Alu	AluSz
CAediting_4112	chr1_3786306_-	SINE	Alu	AluSz
CAediting_4113	chr1_3786315_-	SINE	Alu	AluSz
CAediting_4114	chr1_3786318_-	SINE	Alu	AluSz
CAediting_4115	chr1_3786325_-	SINE	Alu	AluSz
CAediting_4116	chr1_3786328_-	SINE	Alu	AluSz
CAediting_4117	chr1_3786368_-	SINE	Alu	AluSz
CAediting_4118	chr1_3786376_-	SINE	Alu	AluSz
CAediting_4119	chr1_3786378_-	SINE	Alu	AluSz
CAediting_4120	chr1_3786388_-	SINE	Alu	AluSz
CAediting_4121	chr1_3786413_-	SINE	Alu	AluSz
CAediting_4122	chr1_3786418_-	SINE	Alu	AluSz
CAediting_4123	chr1_3786464_-	SINE	Alu	AluSz
CAediting_4124	chr1_3786496_-	SINE	Alu	AluSz

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RNA A-to-I editing events in the alternative splicing sites for LRRC47

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000130764.8.LRRC47.

Correlation between RNA A-to-I editing and PSI for ENSG00000130764.8.LRRC47.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for LRRC47

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for LRRC47

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for LRRC47

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_748296	chr10_51299626_+	ENSG00000130764.8	ENST00000479239	hsa-miR-605-3p	3781517	3781524	8mer-1a	3781517	3781539	166	-23.74

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for LRRC47

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000378251.2	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_4048	ENST00000378251.2	chr1_3780493_-	-1836.20	-1833.70	-1842.20
CAediting_4049	ENST00000378251.2	chr1_3780712_-	-1833.30	-1833.70	-1842.20
CAediting_4050	ENST00000378251.2	chr1_3780716_-	-1836.30	-1833.70	-1842.20
CAediting_4051	ENST00000378251.2	chr1_3780748_-	-1833.60	-1833.70	-1842.20
CAediting_4052	ENST00000378251.2	chr1_3780759_-	-1835.50	-1833.70	-1842.20
CAediting_4053	ENST00000378251.2	chr1_3780810_-	-1833.70	-1833.70	-1842.20
CAediting_4054	ENST00000378251.2	chr1_3780828_-	-1833.20	-1833.70	-1842.20
CAediting_4055	ENST00000378251.2	chr1_3780832_-	-1833.70	-1833.70	-1842.20
CAediting_4056	ENST00000378251.2	chr1_3780864_-	-1833.60	-1833.70	-1842.20
CAediting_4057	ENST00000378251.2	chr1_3780876_-	-1833.00	-1833.70	-1842.20
CAediting_4058	ENST00000378251.2	chr1_3780914_-	-1833.00	-1833.70	-1842.20

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Relation with ADAR for LRRC47

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_4048	chr1_3780493_-	0.017684746927035	0.253812916627219	.	.	.	.

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Relation with cancer stages for LRRC47

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for LRRC47

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for LRRC47

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for LRRC47

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene