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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: PTGDS (CAeditome ID:5730) |
Gene summary for PTGDS |
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Gene information | Gene symbol | PTGDS | Gene ID | 5730 |
Gene name | prostaglandin D2 synthase | |
Synonyms | L-PGDS|LPGDS|PDS|PGD2|PGDS|PGDS2 | |
Cytomap | 9q34.3 | |
Type of gene | protein-coding | |
Description | prostaglandin-H2 D-isomerasePGD2 synthasebeta-trace proteincerebrin-28glutathione-independent PGD synthaseglutathione-independent PGD synthetaselipocalin-type prostaglandin D synthaseprostaglandin D synthaseprostaglandin D2 synthase 21kDa (brain) | |
Modification date | 20210518 | |
UniProtAcc | P41222 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
PTGDS | GO:0004667 | Prostaglandin-H2 D-isomerase | 20347284 |
PTGDS | GO:0004667 | Prostaglandin-H2 D-isomerase | 20667974 |
PTGDS | GO:0005504 | Prostaglandin-H2 D-isomerase | 20667974 |
PTGDS | GO:0001516 | Prostaglandin-H2 D-isomerase | 20347284 |
PTGDS | GO:0001516 | Prostaglandin-H2 D-isomerase | 20667974 |
PTGDS | GO:0005576 | Prostaglandin-H2 D-isomerase | 7692978 |
PTGDS | GO:0005615 | Prostaglandin-H2 D-isomerase | 19878301 |
PTGDS | GO:0005791 | Prostaglandin-H2 D-isomerase | 9065498 |
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RNA A-to-I events for PTGDS |
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CAediting_723411(136977585, +), |
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RNA editing positional annotations for PTGDS using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
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CAeditome ID | Position | Variant type |
CAediting_723411 | chr9_136977585_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
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RNA A-to-I editing events in the alternative splicing sites for PTGDS |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for PTGDS |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for PTGDS |
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The effects of the RNA editing to the miRNA binding sites for PTGDS |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_1351755 | chr19_40282625_- | ENSG00000107317.10 | ENST00000446677 | hsa-miR-641 | 136981634 | 136981640 | 7mer-m8 | 136981613 | 136981641 | 148 | -25.47 |
CAediting_524911 | chr7_5495852_- | ENSG00000107317.10 | ENST00000446677 | hsa-miR-589-3p | 136981627 | 136981632 | 6mer | 136981625 | 136981648 | 145 | -19.07 |
CAediting_524911 | chr7_5495852_- | ENSG00000107317.10 | ENST00000446677 | hsa-miR-589-3p | 136981641 | 136981647 | 7mer-m8 | 136981625 | 136981648 | 145 | -19.07 |
CAediting_1351755 | chr19_40282625_- | ENSG00000107317.10 | ENST00000444903 | hsa-miR-641 | 136981634 | 136981640 | 7mer-m8 | 136981613 | 136981641 | 148 | -25.47 |
CAediting_524911 | chr7_5495852_- | ENSG00000107317.10 | ENST00000444903 | hsa-miR-589-3p | 136981627 | 136981632 | 6mer | 136981625 | 136981648 | 145 | -19.07 |
CAediting_524911 | chr7_5495852_- | ENSG00000107317.10 | ENST00000444903 | hsa-miR-589-3p | 136981641 | 136981647 | 7mer-m8 | 136981625 | 136981648 | 145 | -19.07 |
CAediting_1229414 | chr17_67471546_+ | ENSG00000107317.10 | ENST00000471521 | hsa-miR-548aa | 136983650 | 136983657 | 8mer-1a | 136983633 | 136983657 | 164 | -19.46 |
CAediting_396018 | chr5_1062918_- | ENSG00000107317.10 | ENST00000471521 | hsa-miR-4635 | 136983687 | 136983693 | 7mer-m8 | 136983673 | 136983694 | 148 | -21.3 |
CAediting_580943 | chr7_100356700_+ | ENSG00000107317.10 | ENST00000471521 | hsa-miR-6840-3p | 136985416 | 136985422 | 7mer-m8 | 136985402 | 136985423 | 148 | -26.04 |
CAediting_1524209 | chrX_134546392_- | ENSG00000107317.10 | ENST00000471521 | hsa-miR-503-5p | 136985123 | 136985128 | 6mer | 136985109 | 136985129 | 148 | -31.14 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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The effects of the RNA editing to the stability of the RNA structures for PTGDS |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
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Relation with ADAR for PTGDS |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for PTGDS |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for PTGDS |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for PTGDS |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
PTGDS | P41222 | DB00162 | Vitamin A | Prostaglandin-H2 D-isomerase | SmallMoleculeDrug | approved|nutraceutical|vet_approved |
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RelatedDiseases for PTGDS |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |
PTGDS | C0005586 | Bipolar Disorder | 2 | PSYGENET |