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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: RTN4 (CAeditome ID:57142)

Gene summary for RTN4

check button Gene summary
Gene informationGene symbol

RTN4

Gene ID

57142

Gene namereticulon 4
SynonymsASY|NI220/250|NOGO|NSP|NSP-CL|Nbla00271|Nbla10545|RTN-X|RTN4-A|RTN4-B1|RTN4-B2|RTN4-C
Cytomap

2p16.1

Type of geneprotein-coding
Descriptionreticulon-4Human NogoAMy043 proteinfoocenneurite growth inhibitor 220neurite outgrowth inhibitorneuroendocrine-specific protein C homologreticulon 5
Modification date20210531
UniProtAcc

Q9NQC3

Context- 30078441(RTN4 Knockdown Dysregulates the AKT Pathway, Destabilizes the Cytoskeleton, and Enhances Paclitaxel-Induced Cytotoxicity in Cancers)

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
RTN4

GO:0030517

Reticulon-4

10667797

RTN4

GO:0071787

Reticulon-4

24262037

RTN4

GO:0071787

Reticulon-4

25612671

RTN4

GO:1902430

Reticulon-4

15286784

RTN4

GO:1905552

Reticulon-4

27353365

RTN4

GO:0005635

Reticulon-4

11126360

RTN4

GO:0005783

Reticulon-4

0000052

RTN4

GO:0005789

Reticulon-4

25612671

RTN4

GO:0005789

Reticulon-4

26906412

RTN4

GO:0030176

Reticulon-4

10667797

RTN4

GO:0071782

Reticulon-4

27353365

RTN4

GO:0098826

Reticulon-4

27619977


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RNA A-to-I events for RTN4

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000115310.16
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_181693(54974372, -), CAediting_181694(54974382, -), CAediting_181695(54974417, -), CAediting_181696(54974426, -), CAediting_181697(54974454, -), CAediting_181698(54974459, -), CAediting_181699(54974476, -), CAediting_181700(54974497, -), CAediting_181701(54974508, -), CAediting_181702(54974518, -), CAediting_181703(54974532, -), CAediting_181704(54974537, -), CAediting_181705(54974567, -), CAediting_181706(54978160, -), CAediting_181707(54978171, -), CAediting_181708(54978173, -), CAediting_181709(54978213, -), CAediting_181710(54978246, -), CAediting_181711(54978264, -), CAediting_181712(54978281, -), CAediting_181713(54978292, -), CAediting_181714(54978308, -), CAediting_181715(54978322, -), CAediting_181716(54978330, -), CAediting_181717(54978373, -), CAediting_181718(54978379, -), CAediting_181719(54978398, -), CAediting_181720(54978409, -), CAediting_181721(54978423, -), CAediting_181722(54978425, -), CAediting_181723(54978429, -), CAediting_181724(54979092, -), CAediting_181725(54979116, -), CAediting_181726(54979119, -), CAediting_181727(54979130, -), CAediting_181728(54979146, -), CAediting_181729(54979151, -), CAediting_181730(54979163, -), CAediting_181731(54979164, -), CAediting_181732(54979185, -), CAediting_181733(54979191, -), CAediting_181734(54979213, -), CAediting_181735(54979217, -), CAediting_181736(54979262, -), CAediting_181737(54979290, -), CAediting_181738(54979308, -), CAediting_181739(54979309, -), CAediting_181740(54979314, -), CAediting_181741(54979330, -), CAediting_181742(54979331, -), CAediting_181743(54979339, -), CAediting_181744(54979878, -), CAediting_181745(54982017, -), CAediting_181746(54982066, -), CAediting_181747(54982081, -), CAediting_181748(54982089, -), CAediting_181749(54982094, -), CAediting_181750(54982117, -), CAediting_181751(54982134, -), CAediting_181752(54982138, -), CAediting_181753(54982149, -), CAediting_181754(54982183, -), CAediting_181755(54982188, -), CAediting_181756(54982229, -), CAediting_181757(54982235, -), CAediting_181758(54982237, -), CAediting_181759(54984888, -), CAediting_181760(54984902, -), CAediting_181761(54984909, -), CAediting_181762(54985270, -), CAediting_181763(54985391, -), CAediting_181764(54985432, -), CAediting_181765(54988234, -), CAediting_181766(54988872, -), CAediting_181767(54990987, -), CAediting_181768(54990988, -), CAediting_181769(54991000, -), CAediting_181770(54991055, -), CAediting_181771(54991068, -), CAediting_181772(54991073, -), CAediting_181773(54995158, -), CAediting_181774(54995188, -), CAediting_181775(54996892, -), CAediting_181776(54996895, -), CAediting_181777(55011306, -), CAediting_181778(55014623, -), CAediting_181779(55014681, -), CAediting_181780(55016471, -), CAediting_181781(55020767, -), CAediting_181782(55020806, -), CAediting_181783(55020843, -), CAediting_181784(55021595, -), CAediting_181785(55032177, -), CAediting_181786(55032178, -), CAediting_181787(55032212, -), CAediting_181788(55032217, -), CAediting_181789(55032244, -), CAediting_181790(55032250, -), CAediting_181791(55032251, -), CAediting_181792(55032259, -), CAediting_181793(55032297, -), CAediting_181794(55032334, -), CAediting_181795(55032358, -), CAediting_181796(55032765, -), CAediting_181797(55032798, -), CAediting_181798(55032836, -), CAediting_181799(55032863, -), CAediting_181800(55032873, -), CAediting_181801(55032874, -), CAediting_181802(55032968, -), CAediting_181803(55033023, -), CAediting_181804(55034280, -), CAediting_181805(55034283, -), CAediting_181806(55034419, -), CAediting_181807(55034488, -), CAediting_181808(55054712, -),

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RNA editing positional annotations for RTN4 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_181693chr2_54974372_-ncRNA_intronic
CAediting_181694chr2_54974382_-ncRNA_intronic
CAediting_181695chr2_54974417_-ncRNA_intronic
CAediting_181696chr2_54974426_-ncRNA_intronic
CAediting_181697chr2_54974454_-ncRNA_intronic
CAediting_181698chr2_54974459_-ncRNA_intronic
CAediting_181699chr2_54974476_-ncRNA_intronic
CAediting_181700chr2_54974497_-ncRNA_intronic
CAediting_181701chr2_54974508_-ncRNA_intronic
CAediting_181702chr2_54974518_-ncRNA_intronic
CAediting_181703chr2_54974532_-ncRNA_intronic
CAediting_181704chr2_54974537_-ncRNA_intronic
CAediting_181705chr2_54974567_-ncRNA_intronic
CAediting_181706chr2_54978160_-ncRNA_intronic
CAediting_181707chr2_54978171_-ncRNA_intronic
CAediting_181708chr2_54978173_-ncRNA_intronic
CAediting_181709chr2_54978213_-ncRNA_intronic
CAediting_181710chr2_54978246_-ncRNA_intronic
CAediting_181711chr2_54978264_-ncRNA_intronic
CAediting_181712chr2_54978281_-ncRNA_intronic
CAediting_181713chr2_54978292_-ncRNA_intronic
CAediting_181714chr2_54978308_-ncRNA_intronic
CAediting_181715chr2_54978322_-ncRNA_intronic
CAediting_181716chr2_54978330_-ncRNA_intronic
CAediting_181717chr2_54978373_-ncRNA_intronic
CAediting_181718chr2_54978379_-ncRNA_intronic
CAediting_181719chr2_54978398_-ncRNA_intronic
CAediting_181720chr2_54978409_-ncRNA_intronic
CAediting_181721chr2_54978423_-ncRNA_intronic
CAediting_181722chr2_54978425_-ncRNA_intronic
CAediting_181723chr2_54978429_-ncRNA_intronic
CAediting_181724chr2_54979092_-ncRNA_intronic
CAediting_181725chr2_54979116_-ncRNA_intronic
CAediting_181726chr2_54979119_-ncRNA_intronic
CAediting_181727chr2_54979130_-ncRNA_intronic
CAediting_181728chr2_54979146_-ncRNA_intronic
CAediting_181729chr2_54979151_-ncRNA_intronic
CAediting_181730chr2_54979163_-ncRNA_intronic
CAediting_181731chr2_54979164_-ncRNA_intronic
CAediting_181732chr2_54979185_-ncRNA_intronic
CAediting_181733chr2_54979191_-ncRNA_intronic
CAediting_181734chr2_54979213_-ncRNA_intronic
CAediting_181735chr2_54979217_-ncRNA_intronic
CAediting_181736chr2_54979262_-ncRNA_intronic
CAediting_181737chr2_54979290_-ncRNA_intronic
CAediting_181738chr2_54979308_-ncRNA_intronic
CAediting_181739chr2_54979309_-ncRNA_intronic
CAediting_181740chr2_54979314_-ncRNA_intronic
CAediting_181741chr2_54979330_-ncRNA_intronic
CAediting_181742chr2_54979331_-ncRNA_intronic
CAediting_181743chr2_54979339_-ncRNA_intronic
CAediting_181744chr2_54979878_-ncRNA_intronic
CAediting_181745chr2_54982017_-ncRNA_intronic
CAediting_181746chr2_54982066_-ncRNA_intronic
CAediting_181747chr2_54982081_-ncRNA_intronic
CAediting_181748chr2_54982089_-ncRNA_intronic
CAediting_181749chr2_54982094_-ncRNA_intronic
CAediting_181750chr2_54982117_-ncRNA_intronic
CAediting_181751chr2_54982134_-ncRNA_intronic
CAediting_181752chr2_54982138_-ncRNA_intronic
CAediting_181753chr2_54982149_-ncRNA_intronic
CAediting_181754chr2_54982183_-ncRNA_intronic
CAediting_181755chr2_54982188_-ncRNA_intronic
CAediting_181756chr2_54982229_-ncRNA_intronic
CAediting_181757chr2_54982235_-ncRNA_intronic
CAediting_181758chr2_54982237_-ncRNA_intronic
CAediting_181759chr2_54984888_-ncRNA_intronic
CAediting_181760chr2_54984902_-ncRNA_intronic
CAediting_181761chr2_54984909_-ncRNA_intronic
CAediting_181762chr2_54985270_-ncRNA_intronic
CAediting_181763chr2_54985391_-ncRNA_intronic
CAediting_181764chr2_54985432_-ncRNA_intronic
CAediting_181765chr2_54988234_-intronic
CAediting_181766chr2_54988872_-intronic
CAediting_181767chr2_54990987_-intronic
CAediting_181768chr2_54990988_-intronic
CAediting_181769chr2_54991000_-intronic
CAediting_181770chr2_54991055_-intronic
CAediting_181771chr2_54991068_-intronic
CAediting_181772chr2_54991073_-intronic
CAediting_181773chr2_54995158_-intronic
CAediting_181774chr2_54995188_-intronic
CAediting_181775chr2_54996892_-intronic
CAediting_181776chr2_54996895_-intronic
CAediting_181777chr2_55011306_-intronic
CAediting_181778chr2_55014623_-intronic
CAediting_181779chr2_55014681_-intronic
CAediting_181780chr2_55016471_-intronic
CAediting_181781chr2_55020767_-intronic
CAediting_181782chr2_55020806_-intronic
CAediting_181783chr2_55020843_-intronic
CAediting_181784chr2_55021595_-intronic
CAediting_181785chr2_55032177_-intronic
CAediting_181786chr2_55032178_-intronic
CAediting_181787chr2_55032212_-intronic
CAediting_181788chr2_55032217_-intronic
CAediting_181789chr2_55032244_-intronic
CAediting_181790chr2_55032250_-intronic
CAediting_181791chr2_55032251_-intronic
CAediting_181792chr2_55032259_-intronic
CAediting_181793chr2_55032297_-intronic
CAediting_181794chr2_55032334_-intronic
CAediting_181795chr2_55032358_-intronic
CAediting_181796chr2_55032765_-intronic
CAediting_181797chr2_55032798_-intronic
CAediting_181798chr2_55032836_-intronic
CAediting_181799chr2_55032863_-intronic
CAediting_181800chr2_55032873_-intronic
CAediting_181801chr2_55032874_-intronic
CAediting_181802chr2_55032968_-intronic
CAediting_181803chr2_55033023_-intronic
CAediting_181804chr2_55034280_-intronic
CAediting_181805chr2_55034283_-intronic
CAediting_181806chr2_55034419_-intronic
CAediting_181807chr2_55034488_-intronic
CAediting_181808chr2_55054712_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_181693chr2_54974372_-SINEAluAluSq2
CAediting_181694chr2_54974382_-SINEAluAluSq2
CAediting_181695chr2_54974417_-SINEAluAluSq2
CAediting_181696chr2_54974426_-SINEAluAluSq2
CAediting_181697chr2_54974454_-SINEAluAluSq2
CAediting_181698chr2_54974459_-SINEAluAluSq2
CAediting_181699chr2_54974476_-SINEAluAluSq2
CAediting_181700chr2_54974497_-SINEAluAluSq2
CAediting_181701chr2_54974508_-SINEAluAluSq2
CAediting_181702chr2_54974518_-SINEAluAluSq2
CAediting_181703chr2_54974532_-SINEAluAluSq2
CAediting_181704chr2_54974537_-SINEAluAluSq2
CAediting_181705chr2_54974567_-SINEAluAluSq2
CAediting_181706chr2_54978160_-SINEAluAluSx1
CAediting_181707chr2_54978171_-SINEAluAluSx1
CAediting_181708chr2_54978173_-SINEAluAluSx1
CAediting_181709chr2_54978213_-SINEAluAluSx1
CAediting_181710chr2_54978246_-SINEAluAluSx1
CAediting_181711chr2_54978264_-SINEAluAluSx1
CAediting_181712chr2_54978281_-SINEAluAluSx1
CAediting_181713chr2_54978292_-SINEAluAluSx1
CAediting_181714chr2_54978308_-SINEAluAluSx1
CAediting_181715chr2_54978322_-SINEAluAluSx1
CAediting_181716chr2_54978330_-SINEAluAluSx1
CAediting_181717chr2_54978373_-SINEAluAluSx1
CAediting_181718chr2_54978379_-SINEAluAluSx1
CAediting_181719chr2_54978398_-SINEAluAluSx1
CAediting_181720chr2_54978409_-SINEAluAluSx1
CAediting_181721chr2_54978423_-SINEAluAluSx1
CAediting_181722chr2_54978425_-SINEAluAluSx1
CAediting_181723chr2_54978429_-SINEAluAluSx1
CAediting_181724chr2_54979092_-SINEAluAluJr
CAediting_181725chr2_54979116_-SINEAluAluJr
CAediting_181726chr2_54979119_-SINEAluAluJr
CAediting_181727chr2_54979130_-SINEAluAluJr
CAediting_181728chr2_54979146_-SINEAluAluJr
CAediting_181729chr2_54979151_-SINEAluAluJr
CAediting_181730chr2_54979163_-SINEAluAluJr
CAediting_181731chr2_54979164_-SINEAluAluJr
CAediting_181732chr2_54979185_-SINEAluAluJr
CAediting_181733chr2_54979191_-SINEAluAluJr
CAediting_181734chr2_54979213_-SINEAluAluJr
CAediting_181735chr2_54979217_-SINEAluAluJr
CAediting_181736chr2_54979262_-SINEAluAluJr
CAediting_181737chr2_54979290_-SINEAluAluJr
CAediting_181738chr2_54979308_-SINEAluAluJr
CAediting_181739chr2_54979309_-SINEAluAluJr
CAediting_181740chr2_54979314_-SINEAluAluJr
CAediting_181741chr2_54979330_-SINEAluAluJr
CAediting_181742chr2_54979331_-SINEAluAluJr
CAediting_181743chr2_54979339_-SINEAluAluJr
CAediting_181745chr2_54982017_-SINEAluAluSp
CAediting_181746chr2_54982066_-SINEAluAluSp
CAediting_181747chr2_54982081_-SINEAluAluSp
CAediting_181748chr2_54982089_-SINEAluAluSp
CAediting_181749chr2_54982094_-SINEAluAluSp
CAediting_181750chr2_54982117_-SINEAluAluSp
CAediting_181751chr2_54982134_-SINEAluAluSp
CAediting_181752chr2_54982138_-SINEAluAluSp
CAediting_181753chr2_54982149_-SINEAluAluSp
CAediting_181754chr2_54982183_-SINEAluAluSp
CAediting_181755chr2_54982188_-SINEAluAluSp
CAediting_181756chr2_54982229_-SINEAluAluSp
CAediting_181757chr2_54982235_-SINEAluAluSp
CAediting_181758chr2_54982237_-SINEAluAluSp
CAediting_181759chr2_54984888_-SINEAluFLAM_A
CAediting_181760chr2_54984902_-SINEAluFLAM_A
CAediting_181761chr2_54984909_-SINEAluFLAM_A
CAediting_181762chr2_54985270_-SINEAluAluJr
CAediting_181763chr2_54985391_-SINEAluAluJr
CAediting_181764chr2_54985432_-SINEAluAluJr
CAediting_181765chr2_54988234_-SINEAluAluSz6
CAediting_181767chr2_54990987_-SINEAluAluY
CAediting_181768chr2_54990988_-SINEAluAluY
CAediting_181769chr2_54991000_-SINEAluAluY
CAediting_181770chr2_54991055_-SINEAluAluY
CAediting_181771chr2_54991068_-SINEAluAluY
CAediting_181772chr2_54991073_-SINEAluAluY
CAediting_181773chr2_54995158_-SINEAluAluSx1
CAediting_181774chr2_54995188_-SINEAluAluSx1
CAediting_181775chr2_54996892_-SINEAluAluJb
CAediting_181776chr2_54996895_-SINEAluAluJb
CAediting_181777chr2_55011306_-SINEAluAluJo
CAediting_181778chr2_55014623_-SINEAluAluSc
CAediting_181779chr2_55014681_-SINEAluAluSc
CAediting_181780chr2_55016471_-SINEAluAluSz
CAediting_181781chr2_55020767_-SINEAluAluJb
CAediting_181782chr2_55020806_-SINEAluAluJb
CAediting_181783chr2_55020843_-SINEAluAluJb
CAediting_181784chr2_55021595_-SINEAluFLAM_C
CAediting_181785chr2_55032177_-SINEAluAluSx1
CAediting_181786chr2_55032178_-SINEAluAluSx1
CAediting_181787chr2_55032212_-SINEAluAluSx1
CAediting_181788chr2_55032217_-SINEAluAluSx1
CAediting_181789chr2_55032244_-SINEAluAluSx1
CAediting_181790chr2_55032250_-SINEAluAluSx1
CAediting_181791chr2_55032251_-SINEAluAluSx1
CAediting_181792chr2_55032259_-SINEAluAluSx1
CAediting_181793chr2_55032297_-SINEAluAluSx1
CAediting_181794chr2_55032334_-SINEAluAluSx1
CAediting_181795chr2_55032358_-SINEAluAluSx1
CAediting_181796chr2_55032765_-SINEAluAluJr
CAediting_181797chr2_55032798_-SINEAluAluJr
CAediting_181798chr2_55032836_-SINEAluAluJr
CAediting_181799chr2_55032863_-SINEAluAluJr
CAediting_181800chr2_55032873_-SINEAluAluJr
CAediting_181801chr2_55032874_-SINEAluAluJr
CAediting_181802chr2_55032968_-SINEAluAluJr
CAediting_181803chr2_55033023_-SINEAluAluJr
CAediting_181804chr2_55034280_-SINEAluAluJr
CAediting_181805chr2_55034283_-SINEAluAluJr
CAediting_181806chr2_55034419_-SINEAluAluJr
CAediting_181807chr2_55034488_-SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for RTN4

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000115310.16.RTN4.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000115310.16.RTN4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for RTN4

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for RTN4

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for RTN4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000394609hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000405240hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000357376hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000337526hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000317610hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000357732hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000394611hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37
CAediting_1160181chr17_7017644_-ENSG00000115310.16ENST00000404909hsa-miR-195-3p54972318549723247mer-m85497231754972337153-9.37

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for RTN4

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for RTN4

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
STADCAediting_181728chr2_54979146_-0.01870611927858240.251658013309417....

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Relation with cancer stages for RTN4

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for RTN4

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for RTN4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RTN4

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
RTN4C0023893Liver Cirrhosis, Experimental1CTD_human
RTN4C0036341Schizophrenia1CTD_human