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![]() | Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples |
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![]() | The effects of the RNA editing to the stability of the RNA structures |
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Editing gene: ENY2 (CAeditome ID:56943) |
Gene summary for ENY2 |
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Gene information | Gene symbol | ENY2 | Gene ID | 56943 |
Gene name | ENY2 transcription and export complex 2 subunit | |
Synonyms | DC6|Sus1|e(y)2 | |
Cytomap | 8q23.1 | |
Type of gene | protein-coding | |
Description | transcription and mRNA export factor ENY2enhancer of yellow 2 homologenhancer of yellow 2 transcription factor homolog | |
Modification date | 20210518 | |
UniProtAcc | Q9NPA8 | |
Context |
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Gene | GO ID | GO term | PubMed ID |
ENY2 | GO:0003713 | Transcription and mRNA export factor ENY2 | 18206972 |
ENY2 | GO:0030374 | Transcription and mRNA export factor ENY2 | 18206972 |
ENY2 | GO:0016578 | Transcription and mRNA export factor ENY2 | 18206972 |
ENY2 | GO:0045893 | Transcription and mRNA export factor ENY2 | 18206972 |
ENY2 | GO:0005654 | Transcription and mRNA export factor ENY2 | 0000052 |
ENY2 | GO:0005739 | Transcription and mRNA export factor ENY2 | 0000052 |
ENY2 | GO:0000124 | Transcription and mRNA export factor ENY2 | 18206972 |
ENY2 | GO:0000124 | Transcription and mRNA export factor ENY2 | 23591820 |
ENY2 | GO:0000124 | Transcription and mRNA export factor ENY2 | 27601583 |
ENY2 | GO:0044615 | Transcription and mRNA export factor ENY2 | 23591820 |
ENY2 | GO:0070390 | Transcription and mRNA export factor ENY2 | 23591820 |
ENY2 | GO:0071819 | Transcription and mRNA export factor ENY2 | 27601583 |
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RNA A-to-I events for ENY2 |
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CAediting_656932(109342634, +), CAediting_656933(109342660, +), CAediting_656934(109342734, +), CAediting_656935(109342742, +), |
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RNA editing positional annotations for ENY2 using Annovar |
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CAeditome ID | Position | Variant type | ENST | NTchange | AAchange | SIFT_score | Polyphen2_HVAR_score | PROVEAN_pred |
CAediting_656934 | chr8_109342734_+ | nonsynonymous SNV | ENST00000520147.4 | c.A259G | p.T87A | D | . | N |
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CAeditome ID | Position | Variant type |
CAediting_656932 | chr8_109342634_+ | ncRNA_intronic |
CAediting_656933 | chr8_109342660_+ | ncRNA_intronic |
CAediting_656934 | chr8_109342734_+ | exonic |
CAediting_656935 | chr8_109342742_+ | exonic |
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CAeditome ID | Position | Repeat family | Repeat sub family | Repeat name |
CAediting_656932 | chr8_109342634_+ | SINE | Alu | AluJb |
CAediting_656933 | chr8_109342660_+ | SINE | Alu | AluJb |
CAediting_656934 | chr8_109342734_+ | SINE | Alu | AluJb |
CAediting_656935 | chr8_109342742_+ | SINE | Alu | AluJb |
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RNA A-to-I editing events in the alternative splicing sites for ENY2 |
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AStype | CAeditomID | Editing position | AS position | AS direction | Exonic location | Wildtype sequence | Wildtype splicing strength | RNA edited sequence | RNA edited splicing strength |
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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ENY2 |
![]() * The grey color means N/A. |
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Protein coding region RNA A-to-I editings for ENY2 |
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The effects of the RNA editing to the miRNA binding sites for ENY2 |
**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page. |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_688081 | chr9_63819627_+ | ENSG00000120533.11 | ENST00000521662 | hsa-miR-4477b | 109343625 | 109343632 | 8mer-1a | 109343611 | 109343632 | 144 | -8.45 |
CAediting_748296 | chr10_51299626_+ | ENSG00000120533.11 | ENST00000517311 | hsa-miR-605-3p | 109344775 | 109344781 | 7mer-m8 | 109344757 | 109344782 | 160 | -18.52 |
CAediting_393 | chr1_1167164_+ | ENSG00000120533.11 | ENST00000517311 | hsa-miR-200b-3p | 109344960 | 109344967 | 8mer-1a | 109344946 | 109344967 | 148 | -12.5 |
CAediting_688081 | chr9_63819627_+ | ENSG00000120533.11 | ENST00000517311 | hsa-miR-4477b | 109343625 | 109343632 | 8mer-1a | 109343611 | 109343632 | 144 | -8.45 |
CAediting_688081 | chr9_63819627_+ | ENSG00000120533.11 | ENST00000339942 | hsa-miR-4477b | 109343625 | 109343632 | 8mer-1a | 109343611 | 109343632 | 144 | -8.45 |
CAediting_688081 | chr9_63819627_+ | ENSG00000120533.11 | ENST00000520147 | hsa-miR-4477b | 109343625 | 109343632 | 8mer-1a | 109343611 | 109343632 | 144 | -8.45 |
CAediting_688081 | chr9_63819627_+ | ENSG00000120533.11 | ENST00000523335 | hsa-miR-4477b | 109343625 | 109343632 | 8mer-1a | 109343611 | 109343632 | 144 | -8.45 |
CAediting_1229415 | chr17_67471547_+ | ENSG00000120533.11 | ENST00000517311 | hsa-miR-548aa | 109344673 | 109344680 | 8mer-1a | 109344653 | 109344680 | 149 | -11.8 |
CAediting_1306323 | chr19_13836462_- | ENSG00000120533.11 | ENST00000517311 | hsa-miR-27a-3p | 109344416 | 109344422 | 7mer-m8 | 109344400 | 109344423 | 157 | -20.94 |
CAediting_86358 | chr1_109598906_+ | ENSG00000120533.11 | ENST00000517311 | hsa-miR-197-5p | 109344123 | 109344130 | 8mer-1a | 109344108 | 109344130 | 150 | -18.08 |
CAediting_1399425 | chr20_1392958_- | ENSG00000120533.11 | ENST00000517311 | hsa-miR-6869-5p | 109345508 | 109345515 | 8mer-1a | 109345494 | 109345515 | 140 | -15.1 |
CAediting_442554 | chr5_154685830_+ | ENSG00000120533.11 | ENST00000517311 | hsa-miR-1303 | 109344454 | 109344461 | 8mer-1a | 109344442 | 109344461 | 152 | -19 |
CAediting_1306323 | chr19_13836462_- | ENSG00000120533.11 | ENST00000523335 | hsa-miR-27a-3p | 109344416 | 109344422 | 7mer-m8 | 109344400 | 109344423 | 157 | -20.94 |
CAediting_86358 | chr1_109598906_+ | ENSG00000120533.11 | ENST00000523335 | hsa-miR-197-5p | 109344123 | 109344130 | 8mer-1a | 109344108 | 109344130 | 150 | -18.08 |
CAediting_442554 | chr5_154685830_+ | ENSG00000120533.11 | ENST00000523335 | hsa-miR-1303 | 109344454 | 109344461 | 8mer-1a | 109344442 | 109344461 | 152 | -19 |
CAediting_468389 | chr6_31355314_- | ENSG00000120533.11 | ENST00000517311 | hsa-miR-6891-5p | 109344247 | 109344253 | 7mer-1a | 109344235 | 109344253 | 141 | -30.4 |
CAediting_468389 | chr6_31355314_- | ENSG00000120533.11 | ENST00000523335 | hsa-miR-6891-5p | 109344247 | 109344253 | 7mer-1a | 109344235 | 109344253 | 141 | -30.4 |
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CAeditom_ID | Position | ENSG | ENST | miRNA | Targetscan start | Targetscan end | Targetscan score | Miranda start | Miranda end | Miranda score | Miranda energy |
CAediting_228905 | chr2_188297554_+ | ENSG00000120533.11 | ENST00000517311 | hsa-miR-561-3p | 109343913 | 109343919 | 7mer-m8 | 109343897 | 109343920 | 154 | -12.92 |
CAediting_1399425 | chr20_1392958_- | ENSG00000120533.11 | ENST00000517311 | hsa-miR-6869-5p | 109344039 | 109344045 | 7mer-m8 | 109344026 | 109344046 | 144 | -14.22 |
CAediting_228905 | chr2_188297554_+ | ENSG00000120533.11 | ENST00000523335 | hsa-miR-561-3p | 109343913 | 109343919 | 7mer-m8 | 109343897 | 109343920 | 154 | -12.92 |
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The effects of the RNA editing to the stability of the RNA structures for ENY2 |
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ENST | ENST type | RNA structure without RNA A-to-I editing. | RNA structure with RNA A-to-I editing. |
ENST00000520147.4 | protein_coding | ![]() | ![]() |
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CAeditom_ID | ENST | Editing_Position | MFE_withoneAI | MFE_withoutAI | MFE_withmultipleAI |
CAediting_656934 | ENST00000520147.4 | chr8_109342734_+ | -203.20 | -200.10 | -204.60 |
CAediting_656935 | ENST00000520147.4 | chr8_109342742_+ | -199.80 | -200.10 | -204.60 |
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Relation with ADAR for ENY2 |
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Cancer | CAeditomID | position | ADAR1 (p-val) | ADAR1 (coeff.) | ADAR2 (p-val) | ADAR2 (coeff.) | ADAR3 (p-val) | ADAR3 (coeff.) |
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Relation with cancer stages for ENY2 |
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Cancer | Stage_type | CAeditomID | position | P-val | Coeff. |
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Relation with survival for ENY2 |
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Cancer | CAeditomID | position | KMpvalue | Coxpvalue | CoxHR |
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RelatedDrugs for ENY2 |
![]() (DrugBank Version 5.1.8 2021-01-03) |
Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ENY2 |
![]() (DisGeNet 7.0) |
Gene | Disease ID | Disease name | # pubmeds | Source |