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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: NCLN (CAeditome ID:56926)

Gene summary for NCLN

check button Gene summary
Gene informationGene symbol

NCLN

Gene ID

56926

Gene namenicalin
SynonymsNET59
Cytomap

19p13.3

Type of geneprotein-coding
Descriptionnicalinnicalin homolognicastrin-like protein
Modification date20210518
UniProtAcc

Q969V3

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
NCLN

GO:0043022

Nicalin

32820719

NCLN

GO:0043254

Nicalin

20538592

NCLN

GO:0061635

Nicalin

20538592

NCLN

GO:0005789

Nicalin

20538592

NCLN

GO:0032991

Nicalin

20538592


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RNA A-to-I events for NCLN

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000125912.9

check button RNA A-to-I editing events in Cancer.
CAediting_1274948(3194193, +), CAediting_1274949(3194194, +), CAediting_1274950(3194204, +), CAediting_1274951(3194218, +), CAediting_1274952(3194219, +), CAediting_1274953(3194220, +), CAediting_1274954(3194222, +), CAediting_1274955(3194223, +), CAediting_1274956(3194226, +), CAediting_1274957(3194228, +), CAediting_1274958(3194231, +), CAediting_1274959(3194232, +), CAediting_1274960(3194236, +), CAediting_1274961(3194252, +), CAediting_1274962(3194262, +), CAediting_1274963(3194263, +), CAediting_1274964(3194303, +), CAediting_1274965(3194304, +), CAediting_1274966(3194311, +), CAediting_1274967(3194328, +), CAediting_1274968(3194338, +), CAediting_1274969(3194340, +), CAediting_1274970(3194368, +), CAediting_1274971(3194372, +), CAediting_1274972(3194774, +), CAediting_1274973(3194782, +), CAediting_1274974(3194812, +), CAediting_1274975(3194814, +), CAediting_1274976(3194820, +), CAediting_1274977(3194900, +), CAediting_1274978(3194901, +), CAediting_1274979(3194910, +), CAediting_1274980(3194924, +), CAediting_1274981(3194935, +), CAediting_1274982(3194974, +), CAediting_1274983(3194993, +), CAediting_1274984(3194996, +), CAediting_1274985(3194997, +), CAediting_1274986(3195045, +), CAediting_1274987(3195053, +), CAediting_1274988(3195059, +), CAediting_1274989(3195067, +), CAediting_1274990(3195084, +), CAediting_1274991(3195103, +), CAediting_1274992(3195110, +), CAediting_1274993(3195114, +), CAediting_1274994(3195123, +), CAediting_1274995(3195127, +), CAediting_1274996(3195134, +), CAediting_1274997(3195147, +), CAediting_1274998(3195167, +), CAediting_1274999(3195271, +), CAediting_1275000(3195293, +), CAediting_1275001(3195324, +), CAediting_1275002(3195330, +), CAediting_1275003(3195354, +), CAediting_1275004(3195367, +), CAediting_1275005(3195379, +), CAediting_1275006(3195402, +), CAediting_1275007(3195448, +), CAediting_1275008(3195456, +), CAediting_1275009(3195460, +), CAediting_1275010(3195511, +), CAediting_1275011(3195647, +), CAediting_1275012(3195651, +), CAediting_1275013(3195671, +), CAediting_1275014(3195697, +), CAediting_1275015(3195719, +), CAediting_1275016(3195773, +), CAediting_1275017(3197465, +), CAediting_1275018(3197481, +), CAediting_1275019(3197485, +), CAediting_1275020(3197516, +), CAediting_1275021(3197541, +), CAediting_1275022(3197571, +), CAediting_1275023(3197804, +), CAediting_1275024(3198386, +), CAediting_1275025(3199853, +), CAediting_1275026(3200187, +), CAediting_1275027(3200361, +), CAediting_1275028(3200429, +), CAediting_1275029(3200572, +), CAediting_1275030(3202709, +), CAediting_1275031(3203058, +), CAediting_1275032(3203123, +), CAediting_1275033(3203188, +), CAediting_1275034(3203265, +), CAediting_1275035(3203298, +), CAediting_1275036(3203535, +), CAediting_1275037(3203539, +), CAediting_1275038(3203542, +), CAediting_1275039(3203561, +), CAediting_1275040(3206621, +), CAediting_1275041(3206626, +), CAediting_1275042(3206634, +), CAediting_1275043(3206635, +), CAediting_1275044(3206649, +), CAediting_1275045(3206650, +), CAediting_1275046(3206654, +), CAediting_1275047(3206658, +), CAediting_1275048(3206659, +), CAediting_1275049(3206686, +), CAediting_1275050(3206702, +), CAediting_1275051(3206709, +), CAediting_1275052(3206715, +), CAediting_1275053(3206716, +), CAediting_1275054(3206761, +), CAediting_1275055(3206784, +), CAediting_1275056(3206877, +), CAediting_1275057(3206901, +), CAediting_1275058(3206951, +), CAediting_1275059(3206961, +), CAediting_1275060(3206963, +), CAediting_1275061(3206967, +), CAediting_1275062(3206974, +), CAediting_1275063(3206997, +), CAediting_1275064(3207007, +), CAediting_1275065(3207009, +), CAediting_1275066(3207033, +), CAediting_1275067(3207045, +), CAediting_1275068(3207046, +), CAediting_1275069(3207058, +), CAediting_1275070(3207059, +), CAediting_1275071(3207076, +), CAediting_1275072(3207077, +), CAediting_1275073(3207085, +), CAediting_1275074(3209404, +),

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RNA editing positional annotations for NCLN using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1274948chr19_3194193_+intronic
CAediting_1274949chr19_3194194_+intronic
CAediting_1274950chr19_3194204_+intronic
CAediting_1274951chr19_3194218_+intronic
CAediting_1274952chr19_3194219_+intronic
CAediting_1274953chr19_3194220_+intronic
CAediting_1274954chr19_3194222_+intronic
CAediting_1274955chr19_3194223_+intronic
CAediting_1274956chr19_3194226_+intronic
CAediting_1274957chr19_3194228_+intronic
CAediting_1274958chr19_3194231_+intronic
CAediting_1274959chr19_3194232_+intronic
CAediting_1274960chr19_3194236_+intronic
CAediting_1274961chr19_3194252_+intronic
CAediting_1274962chr19_3194262_+intronic
CAediting_1274963chr19_3194263_+intronic
CAediting_1274964chr19_3194303_+intronic
CAediting_1274965chr19_3194304_+intronic
CAediting_1274966chr19_3194311_+intronic
CAediting_1274967chr19_3194328_+intronic
CAediting_1274968chr19_3194338_+intronic
CAediting_1274969chr19_3194340_+intronic
CAediting_1274970chr19_3194368_+intronic
CAediting_1274971chr19_3194372_+intronic
CAediting_1274972chr19_3194774_+intronic
CAediting_1274973chr19_3194782_+intronic
CAediting_1274974chr19_3194812_+intronic
CAediting_1274975chr19_3194814_+intronic
CAediting_1274976chr19_3194820_+intronic
CAediting_1274977chr19_3194900_+intronic
CAediting_1274978chr19_3194901_+intronic
CAediting_1274979chr19_3194910_+intronic
CAediting_1274980chr19_3194924_+intronic
CAediting_1274981chr19_3194935_+intronic
CAediting_1274982chr19_3194974_+intronic
CAediting_1274983chr19_3194993_+intronic
CAediting_1274984chr19_3194996_+intronic
CAediting_1274985chr19_3194997_+intronic
CAediting_1274986chr19_3195045_+intronic
CAediting_1274987chr19_3195053_+intronic
CAediting_1274988chr19_3195059_+intronic
CAediting_1274989chr19_3195067_+intronic
CAediting_1274990chr19_3195084_+intronic
CAediting_1274991chr19_3195103_+intronic
CAediting_1274992chr19_3195110_+intronic
CAediting_1274993chr19_3195114_+intronic
CAediting_1274994chr19_3195123_+intronic
CAediting_1274995chr19_3195127_+intronic
CAediting_1274996chr19_3195134_+intronic
CAediting_1274997chr19_3195147_+intronic
CAediting_1274998chr19_3195167_+intronic
CAediting_1274999chr19_3195271_+intronic
CAediting_1275000chr19_3195293_+intronic
CAediting_1275001chr19_3195324_+intronic
CAediting_1275002chr19_3195330_+intronic
CAediting_1275003chr19_3195354_+intronic
CAediting_1275004chr19_3195367_+intronic
CAediting_1275005chr19_3195379_+intronic
CAediting_1275006chr19_3195402_+intronic
CAediting_1275007chr19_3195448_+intronic
CAediting_1275008chr19_3195456_+intronic
CAediting_1275009chr19_3195460_+intronic
CAediting_1275010chr19_3195511_+intronic
CAediting_1275011chr19_3195647_+intronic
CAediting_1275012chr19_3195651_+intronic
CAediting_1275013chr19_3195671_+intronic
CAediting_1275014chr19_3195697_+intronic
CAediting_1275015chr19_3195719_+intronic
CAediting_1275016chr19_3195773_+intronic
CAediting_1275017chr19_3197465_+intronic
CAediting_1275018chr19_3197481_+intronic
CAediting_1275019chr19_3197485_+intronic
CAediting_1275020chr19_3197516_+intronic
CAediting_1275021chr19_3197541_+intronic
CAediting_1275022chr19_3197571_+intronic
CAediting_1275023chr19_3197804_+intronic
CAediting_1275024chr19_3198386_+intronic
CAediting_1275025chr19_3199853_+intronic
CAediting_1275026chr19_3200187_+intronic
CAediting_1275027chr19_3200361_+intronic
CAediting_1275028chr19_3200429_+intronic
CAediting_1275029chr19_3200572_+intronic
CAediting_1275030chr19_3202709_+intronic
CAediting_1275031chr19_3203058_+intronic
CAediting_1275032chr19_3203123_+intronic
CAediting_1275033chr19_3203188_+intronic
CAediting_1275034chr19_3203265_+intronic
CAediting_1275035chr19_3203298_+intronic
CAediting_1275036chr19_3203535_+intronic
CAediting_1275037chr19_3203539_+intronic
CAediting_1275038chr19_3203542_+intronic
CAediting_1275039chr19_3203561_+intronic
CAediting_1275040chr19_3206621_+intronic
CAediting_1275041chr19_3206626_+intronic
CAediting_1275042chr19_3206634_+intronic
CAediting_1275043chr19_3206635_+intronic
CAediting_1275044chr19_3206649_+intronic
CAediting_1275045chr19_3206650_+intronic
CAediting_1275046chr19_3206654_+intronic
CAediting_1275047chr19_3206658_+intronic
CAediting_1275048chr19_3206659_+intronic
CAediting_1275049chr19_3206686_+intronic
CAediting_1275050chr19_3206702_+intronic
CAediting_1275051chr19_3206709_+intronic
CAediting_1275052chr19_3206715_+intronic
CAediting_1275053chr19_3206716_+intronic
CAediting_1275054chr19_3206761_+intronic
CAediting_1275055chr19_3206784_+intronic
CAediting_1275056chr19_3206877_+intronic
CAediting_1275057chr19_3206901_+intronic
CAediting_1275058chr19_3206951_+intronic
CAediting_1275059chr19_3206961_+intronic
CAediting_1275060chr19_3206963_+intronic
CAediting_1275061chr19_3206967_+intronic
CAediting_1275062chr19_3206974_+intronic
CAediting_1275063chr19_3206997_+intronic
CAediting_1275064chr19_3207007_+intronic
CAediting_1275065chr19_3207009_+intronic
CAediting_1275066chr19_3207033_+intronic
CAediting_1275067chr19_3207045_+intronic
CAediting_1275068chr19_3207046_+intronic
CAediting_1275069chr19_3207058_+intronic
CAediting_1275070chr19_3207059_+intronic
CAediting_1275071chr19_3207076_+intronic
CAediting_1275072chr19_3207077_+intronic
CAediting_1275073chr19_3207085_+intronic
CAediting_1275074chr19_3209404_+ncRNA_exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1274948chr19_3194193_+SINEAluAluSq2
CAediting_1274949chr19_3194194_+SINEAluAluSq2
CAediting_1274950chr19_3194204_+SINEAluAluSq2
CAediting_1274951chr19_3194218_+SINEAluAluSq2
CAediting_1274952chr19_3194219_+SINEAluAluSq2
CAediting_1274953chr19_3194220_+SINEAluAluSq2
CAediting_1274954chr19_3194222_+SINEAluAluSq2
CAediting_1274955chr19_3194223_+SINEAluAluSq2
CAediting_1274956chr19_3194226_+SINEAluAluSq2
CAediting_1274957chr19_3194228_+SINEAluAluSq2
CAediting_1274958chr19_3194231_+SINEAluAluSq2
CAediting_1274959chr19_3194232_+SINEAluAluSq2
CAediting_1274960chr19_3194236_+SINEAluAluSq2
CAediting_1274961chr19_3194252_+SINEAluAluSq2
CAediting_1274962chr19_3194262_+SINEAluAluSq2
CAediting_1274963chr19_3194263_+SINEAluAluSq2
CAediting_1274964chr19_3194303_+SINEAluAluSq2
CAediting_1274965chr19_3194304_+SINEAluAluSq2
CAediting_1274966chr19_3194311_+SINEAluAluSq2
CAediting_1274967chr19_3194328_+SINEAluAluSq2
CAediting_1274968chr19_3194338_+SINEAluAluSq2
CAediting_1274969chr19_3194340_+SINEAluAluSq2
CAediting_1274970chr19_3194368_+SINEAluAluSq2
CAediting_1274971chr19_3194372_+SINEAluAluSq2
CAediting_1274972chr19_3194774_+SINEAluAluSz6
CAediting_1274973chr19_3194782_+SINEAluAluSz6
CAediting_1274974chr19_3194812_+SINEAluAluSz6
CAediting_1274975chr19_3194814_+SINEAluAluSz6
CAediting_1274976chr19_3194820_+SINEAluAluSz6
CAediting_1274977chr19_3194900_+SINEAluAluJr
CAediting_1274978chr19_3194901_+SINEAluAluJr
CAediting_1274979chr19_3194910_+SINEAluAluJr
CAediting_1274980chr19_3194924_+SINEAluAluJr
CAediting_1274981chr19_3194935_+SINEAluAluJr
CAediting_1274982chr19_3194974_+SINEAluAluJr
CAediting_1274983chr19_3194993_+SINEAluAluJr
CAediting_1274984chr19_3194996_+SINEAluAluJr
CAediting_1274985chr19_3194997_+SINEAluAluJr
CAediting_1274986chr19_3195045_+SINEAluAluJr
CAediting_1274987chr19_3195053_+SINEAluAluJr
CAediting_1274988chr19_3195059_+SINEAluAluJr
CAediting_1274989chr19_3195067_+SINEAluAluJr
CAediting_1274990chr19_3195084_+SINEAluAluJr
CAediting_1274991chr19_3195103_+SINEAluAluJr
CAediting_1274992chr19_3195110_+SINEAluAluJr
CAediting_1274993chr19_3195114_+SINEAluAluJr
CAediting_1274994chr19_3195123_+SINEAluAluJr
CAediting_1274995chr19_3195127_+SINEAluAluJr
CAediting_1274996chr19_3195134_+SINEAluAluJr
CAediting_1274997chr19_3195147_+SINEAluAluJr
CAediting_1274998chr19_3195167_+SINEAluAluJr
CAediting_1274999chr19_3195271_+SINEAluAluY
CAediting_1275000chr19_3195293_+SINEAluAluY
CAediting_1275001chr19_3195324_+SINEAluAluY
CAediting_1275002chr19_3195330_+SINEAluAluY
CAediting_1275003chr19_3195354_+SINEAluAluY
CAediting_1275004chr19_3195367_+SINEAluAluY
CAediting_1275005chr19_3195379_+SINEAluAluY
CAediting_1275006chr19_3195402_+SINEAluAluY
CAediting_1275007chr19_3195448_+SINEAluAluY
CAediting_1275008chr19_3195456_+SINEAluAluY
CAediting_1275009chr19_3195460_+SINEAluAluY
CAediting_1275010chr19_3195511_+SINEAluAluY
CAediting_1275011chr19_3195647_+SINEAluAluJb
CAediting_1275012chr19_3195651_+SINEAluAluJb
CAediting_1275013chr19_3195671_+SINEAluAluJb
CAediting_1275014chr19_3195697_+SINEAluAluJb
CAediting_1275015chr19_3195719_+SINEAluAluJb
CAediting_1275016chr19_3195773_+SINEAluAluJb
CAediting_1275017chr19_3197465_+SINEAluAluSz6
CAediting_1275018chr19_3197481_+SINEAluAluSz6
CAediting_1275019chr19_3197485_+SINEAluAluSz6
CAediting_1275020chr19_3197516_+SINEAluAluSz6
CAediting_1275021chr19_3197541_+SINEAluAluSz6
CAediting_1275022chr19_3197571_+SINEAluAluSz6
CAediting_1275023chr19_3197804_+SINEAluAluSq2
CAediting_1275024chr19_3198386_+SINEAluAluY
CAediting_1275025chr19_3199853_+SINEAluAluSc8
CAediting_1275026chr19_3200187_+SINEAluAluSx
CAediting_1275027chr19_3200361_+SINEAluAluSx3
CAediting_1275028chr19_3200429_+SINEAluAluSx3
CAediting_1275029chr19_3200572_+SINEAluAluSx3
CAediting_1275030chr19_3202709_+SINEAluFLAM_C
CAediting_1275031chr19_3203058_+SINEAluAluSq2
CAediting_1275032chr19_3203123_+SINEAluAluSq2
CAediting_1275033chr19_3203188_+SINEAluAluSq2
CAediting_1275034chr19_3203265_+SINEAluAluSq2
CAediting_1275035chr19_3203298_+SINEAluAluSq2
CAediting_1275036chr19_3203535_+DNAhAT-CharlieMER20
CAediting_1275037chr19_3203539_+DNAhAT-CharlieMER20
CAediting_1275038chr19_3203542_+DNAhAT-CharlieMER20
CAediting_1275039chr19_3203561_+DNAhAT-CharlieMER20
CAediting_1275040chr19_3206621_+SINEAluAluSx1
CAediting_1275041chr19_3206626_+SINEAluAluSx1
CAediting_1275042chr19_3206634_+SINEAluAluSx1
CAediting_1275043chr19_3206635_+SINEAluAluSx1
CAediting_1275044chr19_3206649_+SINEAluAluSx1
CAediting_1275045chr19_3206650_+SINEAluAluSx1
CAediting_1275046chr19_3206654_+SINEAluAluSx1
CAediting_1275047chr19_3206658_+SINEAluAluSx1
CAediting_1275048chr19_3206659_+SINEAluAluSx1
CAediting_1275049chr19_3206686_+SINEAluAluSx1
CAediting_1275050chr19_3206702_+SINEAluAluSx1
CAediting_1275051chr19_3206709_+SINEAluAluSx1
CAediting_1275052chr19_3206715_+SINEAluAluSx1
CAediting_1275053chr19_3206716_+SINEAluAluSx1
CAediting_1275054chr19_3206761_+SINEAluAluSx1
CAediting_1275055chr19_3206784_+SINEAluAluJr
CAediting_1275056chr19_3206877_+SINEAluAluSx1
CAediting_1275057chr19_3206901_+SINEAluAluSx1
CAediting_1275058chr19_3206951_+SINEAluAluSx1
CAediting_1275059chr19_3206961_+SINEAluAluSx1
CAediting_1275060chr19_3206963_+SINEAluAluSx1
CAediting_1275061chr19_3206967_+SINEAluAluSx1
CAediting_1275062chr19_3206974_+SINEAluAluSx1
CAediting_1275063chr19_3206997_+SINEAluAluSx1
CAediting_1275064chr19_3207007_+SINEAluAluSx1
CAediting_1275065chr19_3207009_+SINEAluAluSx1
CAediting_1275066chr19_3207033_+SINEAluAluSx1
CAediting_1275067chr19_3207045_+SINEAluAluSx1
CAediting_1275068chr19_3207046_+SINEAluAluSx1
CAediting_1275069chr19_3207058_+SINEAluAluSx1
CAediting_1275070chr19_3207059_+SINEAluAluSx1
CAediting_1275071chr19_3207076_+SINEAluAluSx1
CAediting_1275072chr19_3207077_+SINEAluAluSx1
CAediting_1275073chr19_3207085_+SINEAluAluSx1

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RNA A-to-I editing events in the alternative splicing sites for NCLN

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000125912.9.NCLN.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000125912.9.NCLN.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for NCLN

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for NCLN

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for NCLN

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1275074chr19_3209404_+ENSG00000125912.9ENST00000592737hsa-miR-3190-5p320940232094087mer-m832093903209409150.00-19.01
CAediting_1275074chr19_3209404_+ENSG00000125912.9ENST00000592737hsa-miR-338-3p320939832094047mer-m832093833209405149.00-15.49
CAediting_1275074chr19_3209404_+ENSG00000125912.9ENST00000592737hsa-miR-4435320940132094077mer-m832093873209408146.00-18.45
CAediting_1275074chr19_3209404_+ENSG00000125912.9ENST00000592737hsa-miR-4435320940132094077mer-m832093873209408146.00-18.45

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1275074chr19_3209404_+ENSG00000125912.9ENST00000592737hsa-miR-4794320940232094087mer-m832093873209409155-18.36
CAediting_1275074chr19_3209404_+ENSG00000125912.9ENST00000592737hsa-miR-621320939932094057mer-m832093843209406153-26
CAediting_1275074chr19_3209404_+ENSG00000125912.9ENST00000592737hsa-miR-664a-5p320940232094087mer-m832093863209409145-16.62

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000125912.9ENST00000592737hsa-miR-605-3p320917532091817mer-m832091613209182140-14.32
CAediting_393chr1_1167164_+ENSG00000125912.9ENST00000592737hsa-miR-200b-3p320943632094427mer-m832094213209443149-16.2
CAediting_1368054chr19_46709310_-ENSG00000125912.9ENST00000592737hsa-miR-320e320848732084937mer-m832084773208494158-22.87
CAediting_1368054chr19_46709310_-ENSG00000125912.9ENST00000592737hsa-miR-320e320852232085287mer-m832085123208529150-20.34
CAediting_86358chr1_109598906_+ENSG00000125912.9ENST00000592737hsa-miR-197-5p320887132088777mer-m832088563208878153-24.77
CAediting_1399425chr20_1392958_-ENSG00000125912.9ENST00000592737hsa-miR-6869-5p320896932089757mer-m832089553208976140-14.53
CAediting_580943chr7_100356700_+ENSG00000125912.9ENST00000592737hsa-miR-6840-3p320792432079307mer-m832079103207931155-25.03
CAediting_1160181chr17_7017644_-ENSG00000125912.9ENST00000586904hsa-miR-195-3p320591532059217mer-m832058983205922142-10.48
CAediting_580943chr7_100356700_+ENSG00000125912.9ENST00000586904hsa-miR-6840-3p320593932059457mer-m832059263205946160-26.94
CAediting_468389chr6_31355314_-ENSG00000125912.9ENST00000592737hsa-miR-6891-5p320927932092857mer-m832092683209286151-22.75

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_980496chr14_31014685_-ENSG00000125912.9ENST00000592737hsa-miR-624-3p320936232093687mer-m832093493209369142-15.23
CAediting_580943chr7_100356700_+ENSG00000125912.9ENST00000592737hsa-miR-6840-3p320796432079718mer-1a32079503207971151-27.89
CAediting_580943chr7_100356700_+ENSG00000125912.9ENST00000592737hsa-miR-6840-3p320821332082186mer32082053208227142-25.33
CAediting_580943chr7_100356700_+ENSG00000125912.9ENST00000592737hsa-miR-6840-3p320856232085687mer-m832085483208569140-21.99

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for NCLN

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for NCLN

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
LAMLCAediting_1274987chr19_3195053_+..0.02458892233798670.207766769859399..

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Relation with cancer stages for NCLN

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for NCLN

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR
LAMLCAediting_1274987chr19_3195053_+0.009782648459284120.02172537.5748

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RelatedDrugs for NCLN

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for NCLN

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource