CAeditome Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: MAP3K7CL (CAeditome ID:56911)

Gene summary for MAP3K7CL

check button Gene summary
Gene informationGene symbol

MAP3K7CL

Gene ID

56911

Gene nameMAP3K7 C-terminal like
SynonymsC21orf7|HC21ORF7|TAK1L|TAKL|TAKL-1|TAKL-2|TAKL-4
Cytomap

21q21.3

Type of geneprotein-coding
DescriptionMAP3K7 C-terminal-like proteinTAK1-like protein 1TAK1-like protein 2TAK1-like protein 4TGF-beta activated kinase
Modification date20210518
UniProtAcc

P57077

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

Top

RNA A-to-I events for MAP3K7CL

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000156265.14

check button RNA A-to-I editing events in Cancer.
CAediting_1446312(29089102, +), CAediting_1446313(29091527, +), CAediting_1446314(29091553, +), CAediting_1446315(29091704, +), CAediting_1446316(29092926, +), CAediting_1446317(29093065, +), CAediting_1446318(29093084, +), CAediting_1446319(29093687, +), CAediting_1446320(29094795, +), CAediting_1446321(29094801, +), CAediting_1446322(29094802, +), CAediting_1446323(29094807, +), CAediting_1446324(29094816, +), CAediting_1446325(29094871, +), CAediting_1446326(29094878, +), CAediting_1446327(29094879, +), CAediting_1446328(29094881, +), CAediting_1446329(29094912, +), CAediting_1446330(29094928, +), CAediting_1446331(29094932, +), CAediting_1446332(29094967, +), CAediting_1446333(29094978, +), CAediting_1446334(29110450, +), CAediting_1446335(29110452, +), CAediting_1446336(29110660, +), CAediting_1446337(29124078, +), CAediting_1446338(29124100, +), CAediting_1446339(29124151, +), CAediting_1446340(29124152, +), CAediting_1446341(29124196, +), CAediting_1446342(29124207, +), CAediting_1446343(29124223, +), CAediting_1446344(29124247, +), CAediting_1446345(29165807, +), CAediting_1446346(29171552, +), CAediting_1446347(29171617, +), CAediting_1446348(29171622, +), CAediting_1446349(29171632, +), CAediting_1446350(29171637, +), CAediting_1446351(29171643, +), CAediting_1446352(29171646, +), CAediting_1446353(29171647, +), CAediting_1446354(29171648, +), CAediting_1446355(29171650, +), CAediting_1446356(29171652, +), CAediting_1446357(29171656, +), CAediting_1446358(29171657, +), CAediting_1446359(29171661, +), CAediting_1446360(29171665, +), CAediting_1446361(29171666, +), CAediting_1446362(29171686, +), CAediting_1446363(29171692, +), CAediting_1446364(29171696, +), CAediting_1446365(29171709, +), CAediting_1446366(29171713, +), CAediting_1446367(29171716, +), CAediting_1446368(29171719, +), CAediting_1446369(29171732, +), CAediting_1446370(29171739, +), CAediting_1446371(29171741, +), CAediting_1446372(29171748, +), CAediting_1446373(29171752, +), CAediting_1446374(29171762, +), CAediting_1446375(29173733, +), CAediting_1446376(29173802, +), CAediting_1446377(29173922, +),

Top

RNA editing positional annotations for MAP3K7CL using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred
CAediting_1446314chr21_29091553_+nonsynonymous SNVENST00000286791.8c.A110Gp.Y37CDBD
CAediting_1446314chr21_29091553_+nonsynonymous SNVENST00000341618.7c.A110Gp.Y37CDBD
CAediting_1446314chr21_29091553_+nonsynonymous SNVENST00000399947.5c.A110Gp.Y37CDBD
CAediting_1446314chr21_29091553_+nonsynonymous SNVENST00000419845.4c.A110Gp.Y37CDBD
CAediting_1446315chr21_29091704_+nonsynonymous SNVENST00000286791.8c.A170Gp.E57GDBD
CAediting_1446315chr21_29091704_+nonsynonymous SNVENST00000341618.7c.A170Gp.E57GDBD
CAediting_1446315chr21_29091704_+nonsynonymous SNVENST00000399947.5c.A170Gp.E57GDBD

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1446312chr21_29089102_+ncRNA_intronic
CAediting_1446313chr21_29091527_+exonic
CAediting_1446314chr21_29091553_+exonic
CAediting_1446315chr21_29091704_+exonic
CAediting_1446316chr21_29092926_+ncRNA_intronic
CAediting_1446317chr21_29093065_+ncRNA_intronic
CAediting_1446318chr21_29093084_+ncRNA_intronic
CAediting_1446319chr21_29093687_+ncRNA_intronic
CAediting_1446320chr21_29094795_+ncRNA_intronic
CAediting_1446321chr21_29094801_+ncRNA_intronic
CAediting_1446322chr21_29094802_+ncRNA_intronic
CAediting_1446323chr21_29094807_+ncRNA_intronic
CAediting_1446324chr21_29094816_+ncRNA_intronic
CAediting_1446325chr21_29094871_+ncRNA_intronic
CAediting_1446326chr21_29094878_+ncRNA_intronic
CAediting_1446327chr21_29094879_+ncRNA_intronic
CAediting_1446328chr21_29094881_+ncRNA_intronic
CAediting_1446329chr21_29094912_+ncRNA_intronic
CAediting_1446330chr21_29094928_+ncRNA_intronic
CAediting_1446331chr21_29094932_+ncRNA_intronic
CAediting_1446332chr21_29094967_+ncRNA_intronic
CAediting_1446333chr21_29094978_+ncRNA_intronic
CAediting_1446334chr21_29110450_+intronic
CAediting_1446335chr21_29110452_+intronic
CAediting_1446336chr21_29110660_+intronic
CAediting_1446337chr21_29124078_+ncRNA_intronic
CAediting_1446338chr21_29124100_+ncRNA_intronic
CAediting_1446339chr21_29124151_+ncRNA_intronic
CAediting_1446340chr21_29124152_+ncRNA_intronic
CAediting_1446341chr21_29124196_+ncRNA_intronic
CAediting_1446342chr21_29124207_+ncRNA_intronic
CAediting_1446343chr21_29124223_+ncRNA_intronic
CAediting_1446344chr21_29124247_+ncRNA_intronic
CAediting_1446345chr21_29165807_+ncRNA_intronic
CAediting_1446346chr21_29171552_+ncRNA_intronic
CAediting_1446347chr21_29171617_+ncRNA_intronic
CAediting_1446348chr21_29171622_+ncRNA_intronic
CAediting_1446349chr21_29171632_+ncRNA_intronic
CAediting_1446350chr21_29171637_+ncRNA_intronic
CAediting_1446351chr21_29171643_+ncRNA_intronic
CAediting_1446352chr21_29171646_+ncRNA_intronic
CAediting_1446353chr21_29171647_+ncRNA_intronic
CAediting_1446354chr21_29171648_+ncRNA_intronic
CAediting_1446355chr21_29171650_+ncRNA_intronic
CAediting_1446356chr21_29171652_+ncRNA_intronic
CAediting_1446357chr21_29171656_+ncRNA_intronic
CAediting_1446358chr21_29171657_+ncRNA_intronic
CAediting_1446359chr21_29171661_+ncRNA_intronic
CAediting_1446360chr21_29171665_+ncRNA_intronic
CAediting_1446361chr21_29171666_+ncRNA_intronic
CAediting_1446362chr21_29171686_+ncRNA_intronic
CAediting_1446363chr21_29171692_+ncRNA_intronic
CAediting_1446364chr21_29171696_+ncRNA_intronic
CAediting_1446365chr21_29171709_+ncRNA_intronic
CAediting_1446366chr21_29171713_+ncRNA_intronic
CAediting_1446367chr21_29171716_+ncRNA_intronic
CAediting_1446368chr21_29171719_+ncRNA_intronic
CAediting_1446369chr21_29171732_+ncRNA_intronic
CAediting_1446370chr21_29171739_+ncRNA_intronic
CAediting_1446371chr21_29171741_+ncRNA_intronic
CAediting_1446372chr21_29171748_+ncRNA_intronic
CAediting_1446373chr21_29171752_+ncRNA_intronic
CAediting_1446374chr21_29171762_+ncRNA_intronic
CAediting_1446375chr21_29173733_+ncRNA_intronic
CAediting_1446376chr21_29173802_+ncRNA_intronic
CAediting_1446377chr21_29173922_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1446312chr21_29089102_+SINEAluAluSg
CAediting_1446313chr21_29091527_+SINEAluAluJr
CAediting_1446314chr21_29091553_+SINEAluAluJr
CAediting_1446315chr21_29091704_+SINEAluAluJr
CAediting_1446316chr21_29092926_+SINEAluAluSz
CAediting_1446317chr21_29093065_+SINEAluAluSz
CAediting_1446318chr21_29093084_+SINEAluAluSz
CAediting_1446319chr21_29093687_+SINEAluAluY
CAediting_1446320chr21_29094795_+SINEAluAluJb
CAediting_1446321chr21_29094801_+SINEAluAluJb
CAediting_1446322chr21_29094802_+SINEAluAluJb
CAediting_1446323chr21_29094807_+SINEAluAluJb
CAediting_1446324chr21_29094816_+SINEAluAluJb
CAediting_1446325chr21_29094871_+SINEAluAluJb
CAediting_1446326chr21_29094878_+SINEAluAluJb
CAediting_1446327chr21_29094879_+SINEAluAluJb
CAediting_1446328chr21_29094881_+SINEAluAluJb
CAediting_1446329chr21_29094912_+SINEAluAluJb
CAediting_1446330chr21_29094928_+SINEAluAluJb
CAediting_1446331chr21_29094932_+SINEAluAluJb
CAediting_1446332chr21_29094967_+SINEAluAluJb
CAediting_1446333chr21_29094978_+SINEAluAluJb
CAediting_1446334chr21_29110450_+SINEAluAluSz
CAediting_1446335chr21_29110452_+SINEAluAluSz
CAediting_1446336chr21_29110660_+SINEAluAluSz
CAediting_1446337chr21_29124078_+SINEAluAluSg4
CAediting_1446338chr21_29124100_+SINEAluAluSg4
CAediting_1446339chr21_29124151_+SINEAluAluSg4
CAediting_1446340chr21_29124152_+SINEAluAluSg4
CAediting_1446341chr21_29124196_+SINEAluAluSg4
CAediting_1446342chr21_29124207_+SINEAluAluSg4
CAediting_1446343chr21_29124223_+SINEAluAluSg4
CAediting_1446344chr21_29124247_+SINEAluAluSg4
CAediting_1446345chr21_29165807_+SINEAluAluSz
CAediting_1446346chr21_29171552_+SINEAluAluSx
CAediting_1446347chr21_29171617_+SINEAluAluSx
CAediting_1446348chr21_29171622_+SINEAluAluSx
CAediting_1446349chr21_29171632_+SINEAluAluSx
CAediting_1446350chr21_29171637_+SINEAluAluSx
CAediting_1446351chr21_29171643_+SINEAluAluSx
CAediting_1446352chr21_29171646_+SINEAluAluSx
CAediting_1446353chr21_29171647_+SINEAluAluSx
CAediting_1446354chr21_29171648_+SINEAluAluSx
CAediting_1446355chr21_29171650_+SINEAluAluSx
CAediting_1446356chr21_29171652_+SINEAluAluSx
CAediting_1446357chr21_29171656_+SINEAluAluSx
CAediting_1446358chr21_29171657_+SINEAluAluSx
CAediting_1446359chr21_29171661_+SINEAluAluSx
CAediting_1446360chr21_29171665_+SINEAluAluSx
CAediting_1446361chr21_29171666_+SINEAluAluSx
CAediting_1446362chr21_29171686_+SINEAluAluSx
CAediting_1446363chr21_29171692_+SINEAluAluSx
CAediting_1446364chr21_29171696_+SINEAluAluSx
CAediting_1446365chr21_29171709_+SINEAluAluSx
CAediting_1446366chr21_29171713_+SINEAluAluSx
CAediting_1446367chr21_29171716_+SINEAluAluSx
CAediting_1446368chr21_29171719_+SINEAluAluSx
CAediting_1446369chr21_29171732_+SINEAluAluSx
CAediting_1446370chr21_29171739_+SINEAluAluSx
CAediting_1446371chr21_29171741_+SINEAluAluSx
CAediting_1446372chr21_29171748_+SINEAluAluSx
CAediting_1446373chr21_29171752_+SINEAluAluSx
CAediting_1446374chr21_29171762_+SINEAluAluSx
CAediting_1446375chr21_29173733_+SINEAluAluJo
CAediting_1446376chr21_29173802_+SINEAluAluJo
CAediting_1446377chr21_29173922_+SINEAluAluJo

Top

RNA A-to-I editing events in the alternative splicing sites for MAP3K7CL

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000156265.14.MAP3K7CL.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000156265.14.MAP3K7CL.

Top

Differntial gene expression between RNA A-to-I edited versus non-edited samples for MAP3K7CL

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

Top

Protein coding region RNA A-to-I editings for MAP3K7CL

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


Top

The effects of the RNA editing to the miRNA binding sites for MAP3K7CL

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_77128chr1_85133844_+ENSG00000156265.14ENST00000341618hsa-miR-4423-3p29175665291756717mer-m82917565029175672148-19.48
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000341618hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_77128chr1_85133844_+ENSG00000156265.14ENST00000399935hsa-miR-4423-3p29175665291756717mer-m82917565029175672148-19.48
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000399935hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_77128chr1_85133844_+ENSG00000156265.14ENST00000399934hsa-miR-4423-3p29175665291756717mer-m82917565029175672148-19.48
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000399934hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_77128chr1_85133844_+ENSG00000156265.14ENST00000399947hsa-miR-4423-3p29175665291756717mer-m82917565029175672148-19.48
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000399947hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_77128chr1_85133844_+ENSG00000156265.14ENST00000286791hsa-miR-4423-3p29175665291756717mer-m82917565029175672148-19.48
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000286791hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_77128chr1_85133844_+ENSG00000156265.14ENST00000339024hsa-miR-4423-3p29175665291756717mer-m82917565029175672148-19.48
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000339024hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_77128chr1_85133844_+ENSG00000156265.14ENST00000545939hsa-miR-4423-3p29175665291756717mer-m82917565029175672148-19.48
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000545939hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000399926hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96
CAediting_1399425chr20_1392958_-ENSG00000156265.14ENST00000399925hsa-miR-6869-5p29174998291750036mer2917498329175004140-20.96

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_228905chr2_188297554_+ENSG00000156265.14ENST00000341618hsa-miR-561-3p29175389291753957mer-m82917537529175396150-6.39
CAediting_228905chr2_188297554_+ENSG00000156265.14ENST00000399935hsa-miR-561-3p29175389291753957mer-m82917537529175396150-6.39
CAediting_228905chr2_188297554_+ENSG00000156265.14ENST00000399934hsa-miR-561-3p29175389291753957mer-m82917537529175396150-6.39
CAediting_228905chr2_188297554_+ENSG00000156265.14ENST00000399947hsa-miR-561-3p29175389291753957mer-m82917537529175396150-6.39
CAediting_228905chr2_188297554_+ENSG00000156265.14ENST00000286791hsa-miR-561-3p29175389291753957mer-m82917537529175396150-6.39
CAediting_228905chr2_188297554_+ENSG00000156265.14ENST00000339024hsa-miR-561-3p29175389291753957mer-m82917537529175396150-6.39
CAediting_228905chr2_188297554_+ENSG00000156265.14ENST00000545939hsa-miR-561-3p29175389291753957mer-m82917537529175396150-6.39

check button Differentially expressed gene-miRNA network

Top

The effects of the RNA editing to the stability of the RNA structures for MAP3K7CL

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

Top

Relation with ADAR for MAP3K7CL

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

Top

Relation with cancer stages for MAP3K7CL

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

Top

Relation with survival for MAP3K7CL

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

Top

RelatedDrugs for MAP3K7CL

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for MAP3K7CL

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource