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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

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Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: MYNN (CAeditome ID:55892)

Gene summary for MYNN

check button Gene summary
Gene informationGene symbol

MYNN

Gene ID

55892

Gene namemyoneurin
SynonymsOSZF|SBBIZ1|ZBTB31|ZNF902
Cytomap

3q26.2

Type of geneprotein-coding
Descriptionmyoneurinzinc finger and BTB domain-containing protein 31zinc finger protein with BTB/POZ domain
Modification date20210518
UniProtAcc

Q9NPC7

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
MYNN

GO:0005654

Myoneurin

0000052


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RNA A-to-I events for MYNN

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000085274.14

check button RNA A-to-I editing events in Cancer.
CAediting_320510(169774862, +), CAediting_320511(169774878, +), CAediting_320512(169774965, +), CAediting_320513(169774980, +), CAediting_320514(169774988, +), CAediting_320515(169783483, +),

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RNA editing positional annotations for MYNN using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_320510chr3_169774862_+intronic
CAediting_320511chr3_169774878_+intronic
CAediting_320512chr3_169774965_+intronic
CAediting_320513chr3_169774980_+intronic
CAediting_320514chr3_169774988_+intronic
CAediting_320515chr3_169783483_+exonic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_320510chr3_169774862_+SINEAluAluSx
CAediting_320511chr3_169774878_+SINEAluAluSx
CAediting_320512chr3_169774965_+SINEAluAluSx
CAediting_320513chr3_169774980_+SINEAluAluSx
CAediting_320514chr3_169774988_+SINEAluAluSx

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RNA A-to-I editing events in the alternative splicing sites for MYNN

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000085274.14.MYNN.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000085274.14.MYNN.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MYNN

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MYNN

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for MYNN

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_748296chr10_51299626_+ENSG00000085274.14ENST00000602751hsa-miR-605-3p1697870431697870508mer-1a169787030169787050154-14.83
CAediting_748296chr10_51299626_+ENSG00000085274.14ENST00000356716hsa-miR-605-3p1697870431697870508mer-1a169787030169787050154-14.83
CAediting_748296chr10_51299626_+ENSG00000085274.14ENST00000544106hsa-miR-605-3p1697870431697870508mer-1a169787030169787050154-14.83
CAediting_524911chr7_5495852_-ENSG00000085274.14ENST00000602751hsa-miR-589-3p1697793011697793088mer-1a169779285169779308146-16.86
CAediting_573000chr7_92204081_-ENSG00000085274.14ENST00000602751hsa-miR-1285-5p1697789411697789477mer-m8169778928169778948141-14.03
CAediting_1229415chr17_67471547_+ENSG00000085274.14ENST00000602751hsa-miR-548aa1697868481697868558mer-1a169786831169786855154-7.9
CAediting_1229415chr17_67471547_+ENSG00000085274.14ENST00000356716hsa-miR-548aa1697868481697868558mer-1a169786831169786855154-7.9
CAediting_1229415chr17_67471547_+ENSG00000085274.14ENST00000544106hsa-miR-548aa1697880341697880407mer-m8169788017169788041150-13.82
CAediting_1229415chr17_67471547_+ENSG00000085274.14ENST00000544106hsa-miR-548aa1697868481697868558mer-1a169786831169786855154-7.9
CAediting_117844chr1_162342605_+ENSG00000085274.14ENST00000544106hsa-miR-556-3p1697885911697885977mer-m8169788577169788598152-10.64

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1160181chr17_7017644_-ENSG00000085274.14ENST00000602751hsa-miR-195-3p1697792461697792516mer169779233169779252143-16.06
CAediting_1160181chr17_7017644_-ENSG00000085274.14ENST00000602751hsa-miR-195-3p1697874481697874547mer-m8169787434169787455140-9.7

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MYNN

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000349841.8protein_codingSoverviewSoverview
ENST00000356716.7protein_codingSoverviewSoverview
ENST00000544106.4protein_codingSoverviewSoverview
ENST00000602751.4nonsense_mediated_decaySoverviewSoverview
ENST00000602391.1nonsense_mediated_decaySoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_320515ENST00000349841.8chr3_169783483_+-1329.60-1329.60-1329.60
CAediting_320515ENST00000356716.7chr3_169783483_+-733.00-732.90-733.00
CAediting_320515ENST00000544106.4chr3_169783483_+-1183.50-1183.40-1183.50
CAediting_320515ENST00000602751.4chr3_169783483_+-677.00-676.90-677.00
CAediting_320515ENST00000602391.1chr3_169783483_+-215.50-215.50-215.50

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Relation with ADAR for MYNN

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for MYNN

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for MYNN

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for MYNN

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for MYNN

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource