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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: ECHDC1 (CAeditome ID:55862)

Gene summary for ECHDC1

check button Gene summary
Gene informationGene symbol

ECHDC1

Gene ID

55862

Gene nameethylmalonyl-CoA decarboxylase 1
SynonymsHEL-S-76|MMCD|dJ351K20.2
Cytomap

6q22.33

Type of geneprotein-coding
Descriptionethylmalonyl-CoA decarboxylaseenoyl CoA hydratase domain containing 1enoyl Coenzyme A hydratase domain containing 1enoyl-CoA hydratase domain-containing protein 1epididymis secretory protein Li 76methylmalonyl-CoA decarboxylase
Modification date20210518
UniProtAcc

Q9NTX5

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for ECHDC1

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000093144.17

check button RNA A-to-I editing events in Cancer.
CAediting_502848(127289608, -), CAediting_502849(127289801, -), CAediting_502850(127290190, -), CAediting_502851(127293719, -), CAediting_502852(127293720, -), CAediting_502853(127293969, -), CAediting_502854(127293991, -), CAediting_502855(127294005, -), CAediting_502856(127294025, -), CAediting_502857(127296290, -), CAediting_502858(127296305, -), CAediting_502859(127296332, -), CAediting_502860(127296356, -), CAediting_502861(127296372, -), CAediting_502862(127296373, -), CAediting_502863(127296839, -), CAediting_502864(127296873, -), CAediting_502865(127296883, -), CAediting_502866(127296892, -), CAediting_502867(127296893, -), CAediting_502868(127296910, -), CAediting_502869(127296922, -), CAediting_502870(127296923, -), CAediting_502871(127296961, -), CAediting_502872(127297002, -), CAediting_502873(127299225, -), CAediting_502874(127299230, -), CAediting_502875(127299664, -), CAediting_502876(127299691, -), CAediting_502877(127299693, -), CAediting_502878(127306397, -), CAediting_502879(127306429, -), CAediting_502880(127306436, -), CAediting_502881(127306476, -), CAediting_502882(127306483, -), CAediting_502883(127306492, -), CAediting_502884(127306493, -), CAediting_502885(127306515, -), CAediting_502886(127306551, -), CAediting_502887(127306553, -), CAediting_502888(127306554, -), CAediting_502889(127306561, -), CAediting_502890(127306567, -), CAediting_502891(127306591, -), CAediting_502892(127306594, -), CAediting_502893(127306606, -), CAediting_502894(127306609, -), CAediting_502895(127306614, -), CAediting_502896(127306618, -), CAediting_502897(127306620, -), CAediting_502898(127306624, -), CAediting_502899(127306625, -), CAediting_502900(127306649, -), CAediting_502901(127306653, -), CAediting_502902(127306662, -), CAediting_502903(127306664, -), CAediting_502904(127306670, -), CAediting_502905(127306681, -), CAediting_502906(127306691, -), CAediting_502907(127306694, -), CAediting_502908(127306695, -), CAediting_502909(127306696, -), CAediting_502910(127306698, -), CAediting_502911(127306702, -), CAediting_502912(127306703, -), CAediting_502913(127306710, -), CAediting_502914(127306724, -), CAediting_502915(127306725, -), CAediting_502916(127306727, -), CAediting_502917(127306746, -), CAediting_502918(127309678, -), CAediting_502919(127309685, -), CAediting_502920(127309699, -), CAediting_502921(127309703, -), CAediting_502922(127309704, -), CAediting_502923(127309719, -), CAediting_502924(127309720, -), CAediting_502925(127309721, -), CAediting_502926(127309747, -), CAediting_502927(127309749, -), CAediting_502928(127309781, -), CAediting_502929(127309782, -), CAediting_502930(127309817, -), CAediting_502931(127309821, -), CAediting_502932(127310004, -), CAediting_502933(127310005, -), CAediting_502934(127313282, -), CAediting_502935(127320296, -), CAediting_502936(127320303, -), CAediting_502937(127320311, -), CAediting_502938(127321811, -), CAediting_502939(127322043, -), CAediting_502940(127322049, -), CAediting_502941(127325982, -),

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RNA editing positional annotations for ECHDC1 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_502848chr6_127289608_-UTR3
CAediting_502849chr6_127289801_-ncRNA_exonic
CAediting_502850chr6_127290190_-exonic
CAediting_502851chr6_127293719_-ncRNA_intronic
CAediting_502852chr6_127293720_-ncRNA_intronic
CAediting_502853chr6_127293969_-ncRNA_intronic
CAediting_502854chr6_127293991_-ncRNA_intronic
CAediting_502855chr6_127294005_-ncRNA_intronic
CAediting_502856chr6_127294025_-ncRNA_intronic
CAediting_502857chr6_127296290_-ncRNA_intronic
CAediting_502858chr6_127296305_-ncRNA_intronic
CAediting_502859chr6_127296332_-ncRNA_intronic
CAediting_502860chr6_127296356_-ncRNA_intronic
CAediting_502861chr6_127296372_-ncRNA_intronic
CAediting_502862chr6_127296373_-ncRNA_intronic
CAediting_502863chr6_127296839_-ncRNA_intronic
CAediting_502864chr6_127296873_-ncRNA_intronic
CAediting_502865chr6_127296883_-ncRNA_intronic
CAediting_502866chr6_127296892_-ncRNA_intronic
CAediting_502867chr6_127296893_-ncRNA_intronic
CAediting_502868chr6_127296910_-ncRNA_intronic
CAediting_502869chr6_127296922_-ncRNA_intronic
CAediting_502870chr6_127296923_-ncRNA_intronic
CAediting_502871chr6_127296961_-ncRNA_intronic
CAediting_502872chr6_127297002_-ncRNA_intronic
CAediting_502873chr6_127299225_-ncRNA_intronic
CAediting_502874chr6_127299230_-ncRNA_intronic
CAediting_502875chr6_127299664_-ncRNA_intronic
CAediting_502876chr6_127299691_-ncRNA_intronic
CAediting_502877chr6_127299693_-ncRNA_intronic
CAediting_502878chr6_127306397_-ncRNA_intronic
CAediting_502879chr6_127306429_-ncRNA_intronic
CAediting_502880chr6_127306436_-ncRNA_intronic
CAediting_502881chr6_127306476_-ncRNA_intronic
CAediting_502882chr6_127306483_-ncRNA_intronic
CAediting_502883chr6_127306492_-ncRNA_intronic
CAediting_502884chr6_127306493_-ncRNA_intronic
CAediting_502885chr6_127306515_-ncRNA_intronic
CAediting_502886chr6_127306551_-ncRNA_intronic
CAediting_502887chr6_127306553_-ncRNA_intronic
CAediting_502888chr6_127306554_-ncRNA_intronic
CAediting_502889chr6_127306561_-ncRNA_intronic
CAediting_502890chr6_127306567_-ncRNA_intronic
CAediting_502891chr6_127306591_-ncRNA_intronic
CAediting_502892chr6_127306594_-ncRNA_intronic
CAediting_502893chr6_127306606_-ncRNA_intronic
CAediting_502894chr6_127306609_-ncRNA_intronic
CAediting_502895chr6_127306614_-ncRNA_intronic
CAediting_502896chr6_127306618_-ncRNA_intronic
CAediting_502897chr6_127306620_-ncRNA_intronic
CAediting_502898chr6_127306624_-ncRNA_intronic
CAediting_502899chr6_127306625_-ncRNA_intronic
CAediting_502900chr6_127306649_-ncRNA_intronic
CAediting_502901chr6_127306653_-ncRNA_intronic
CAediting_502902chr6_127306662_-ncRNA_intronic
CAediting_502903chr6_127306664_-ncRNA_intronic
CAediting_502904chr6_127306670_-ncRNA_intronic
CAediting_502905chr6_127306681_-ncRNA_intronic
CAediting_502906chr6_127306691_-ncRNA_intronic
CAediting_502907chr6_127306694_-ncRNA_intronic
CAediting_502908chr6_127306695_-ncRNA_intronic
CAediting_502909chr6_127306696_-ncRNA_intronic
CAediting_502910chr6_127306698_-ncRNA_intronic
CAediting_502911chr6_127306702_-ncRNA_intronic
CAediting_502912chr6_127306703_-ncRNA_intronic
CAediting_502913chr6_127306710_-ncRNA_intronic
CAediting_502914chr6_127306724_-ncRNA_intronic
CAediting_502915chr6_127306725_-ncRNA_intronic
CAediting_502916chr6_127306727_-ncRNA_intronic
CAediting_502917chr6_127306746_-ncRNA_intronic
CAediting_502918chr6_127309678_-ncRNA_intronic
CAediting_502919chr6_127309685_-ncRNA_intronic
CAediting_502920chr6_127309699_-ncRNA_intronic
CAediting_502921chr6_127309703_-ncRNA_intronic
CAediting_502922chr6_127309704_-ncRNA_intronic
CAediting_502923chr6_127309719_-ncRNA_intronic
CAediting_502924chr6_127309720_-ncRNA_intronic
CAediting_502925chr6_127309721_-ncRNA_intronic
CAediting_502926chr6_127309747_-ncRNA_intronic
CAediting_502927chr6_127309749_-ncRNA_intronic
CAediting_502928chr6_127309781_-ncRNA_intronic
CAediting_502929chr6_127309782_-ncRNA_intronic
CAediting_502930chr6_127309817_-ncRNA_intronic
CAediting_502931chr6_127309821_-ncRNA_intronic
CAediting_502932chr6_127310004_-ncRNA_intronic
CAediting_502933chr6_127310005_-ncRNA_intronic
CAediting_502934chr6_127313282_-ncRNA_intronic
CAediting_502935chr6_127320296_-ncRNA_intronic
CAediting_502936chr6_127320303_-ncRNA_intronic
CAediting_502937chr6_127320311_-ncRNA_intronic
CAediting_502938chr6_127321811_-ncRNA_intronic
CAediting_502939chr6_127322043_-ncRNA_intronic
CAediting_502940chr6_127322049_-ncRNA_intronic
CAediting_502941chr6_127325982_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_502857chr6_127296290_-SINEAluAluSx3
CAediting_502858chr6_127296305_-SINEAluAluSx3
CAediting_502859chr6_127296332_-SINEAluAluSx3
CAediting_502860chr6_127296356_-SINEAluAluSx3
CAediting_502861chr6_127296372_-SINEAluAluSx3
CAediting_502862chr6_127296373_-SINEAluAluSx3
CAediting_502863chr6_127296839_-SINEAluAluJb
CAediting_502864chr6_127296873_-SINEAluAluJb
CAediting_502865chr6_127296883_-SINEAluAluJb
CAediting_502866chr6_127296892_-SINEAluAluJb
CAediting_502867chr6_127296893_-SINEAluAluJb
CAediting_502868chr6_127296910_-SINEAluAluJb
CAediting_502869chr6_127296922_-SINEAluAluJb
CAediting_502870chr6_127296923_-SINEAluAluJb
CAediting_502871chr6_127296961_-SINEAluAluJb
CAediting_502872chr6_127297002_-SINEAluAluJb
CAediting_502873chr6_127299225_-DNATcMar-TiggerTigger3b
CAediting_502874chr6_127299230_-DNATcMar-TiggerTigger3b
CAediting_502875chr6_127299664_-DNATcMar-TiggerTigger3b
CAediting_502876chr6_127299691_-DNATcMar-TiggerTigger3b
CAediting_502877chr6_127299693_-DNATcMar-TiggerTigger3b
CAediting_502878chr6_127306397_-LTRERVL-MaLRMSTA
CAediting_502879chr6_127306429_-LTRERVL-MaLRMSTA
CAediting_502880chr6_127306436_-LTRERVL-MaLRMSTA
CAediting_502881chr6_127306476_-LTRERVL-MaLRMSTA
CAediting_502882chr6_127306483_-LTRERVL-MaLRMSTA
CAediting_502883chr6_127306492_-LTRERVL-MaLRMSTA
CAediting_502884chr6_127306493_-LTRERVL-MaLRMSTA
CAediting_502885chr6_127306515_-LTRERVL-MaLRMSTA
CAediting_502886chr6_127306551_-LTRERVL-MaLRMSTA
CAediting_502887chr6_127306553_-LTRERVL-MaLRMSTA
CAediting_502888chr6_127306554_-LTRERVL-MaLRMSTA
CAediting_502889chr6_127306561_-LTRERVL-MaLRMSTA
CAediting_502890chr6_127306567_-LTRERVL-MaLRMSTA
CAediting_502891chr6_127306591_-LTRERVL-MaLRMSTA
CAediting_502892chr6_127306594_-LTRERVL-MaLRMSTA
CAediting_502893chr6_127306606_-LTRERVL-MaLRMSTA
CAediting_502894chr6_127306609_-LTRERVL-MaLRMSTA
CAediting_502895chr6_127306614_-LTRERVL-MaLRMSTA
CAediting_502896chr6_127306618_-LTRERVL-MaLRMSTA
CAediting_502897chr6_127306620_-LTRERVL-MaLRMSTA
CAediting_502898chr6_127306624_-LTRERVL-MaLRMSTA
CAediting_502899chr6_127306625_-LTRERVL-MaLRMSTA
CAediting_502900chr6_127306649_-LTRERVL-MaLRMSTA
CAediting_502901chr6_127306653_-LTRERVL-MaLRMSTA
CAediting_502902chr6_127306662_-LTRERVL-MaLRMSTA
CAediting_502903chr6_127306664_-LTRERVL-MaLRMSTA
CAediting_502904chr6_127306670_-LTRERVL-MaLRMSTA
CAediting_502905chr6_127306681_-LTRERVL-MaLRMSTA
CAediting_502906chr6_127306691_-LTRERVL-MaLRMSTA
CAediting_502907chr6_127306694_-LTRERVL-MaLRMSTA
CAediting_502908chr6_127306695_-LTRERVL-MaLRMSTA
CAediting_502909chr6_127306696_-LTRERVL-MaLRMSTA
CAediting_502910chr6_127306698_-LTRERVL-MaLRMSTA
CAediting_502911chr6_127306702_-LTRERVL-MaLRMSTA
CAediting_502912chr6_127306703_-LTRERVL-MaLRMSTA
CAediting_502913chr6_127306710_-LTRERVL-MaLRMSTA
CAediting_502914chr6_127306724_-LTRERVL-MaLRMSTA
CAediting_502915chr6_127306725_-LTRERVL-MaLRMSTA
CAediting_502916chr6_127306727_-LTRERVL-MaLRMSTA
CAediting_502917chr6_127306746_-LTRERVL-MaLRMSTA
CAediting_502918chr6_127309678_-LTRERVL-MaLRMSTA
CAediting_502919chr6_127309685_-LTRERVL-MaLRMSTA
CAediting_502920chr6_127309699_-LTRERVL-MaLRMSTA
CAediting_502921chr6_127309703_-LTRERVL-MaLRMSTA
CAediting_502922chr6_127309704_-LTRERVL-MaLRMSTA
CAediting_502923chr6_127309719_-LTRERVL-MaLRMSTA
CAediting_502924chr6_127309720_-LTRERVL-MaLRMSTA
CAediting_502925chr6_127309721_-LTRERVL-MaLRMSTA
CAediting_502926chr6_127309747_-LTRERVL-MaLRMSTA
CAediting_502927chr6_127309749_-LTRERVL-MaLRMSTA
CAediting_502928chr6_127309781_-LTRERVL-MaLRMSTA
CAediting_502929chr6_127309782_-LTRERVL-MaLRMSTA
CAediting_502930chr6_127309817_-LTRERVL-MaLRMSTA
CAediting_502931chr6_127309821_-LTRERVL-MaLRMSTA
CAediting_502932chr6_127310004_-LTRERVL-MaLRMSTA
CAediting_502933chr6_127310005_-LTRERVL-MaLRMSTA
CAediting_502934chr6_127313282_-SINEAluAluSx
CAediting_502935chr6_127320296_-SINEAluAluSx1
CAediting_502936chr6_127320303_-SINEAluAluSx1
CAediting_502937chr6_127320311_-SINEAluAluSx1
CAediting_502938chr6_127321811_-SINEAluAluSx1
CAediting_502939chr6_127322043_-SINEAluAluSz
CAediting_502940chr6_127322049_-SINEAluAluSz
CAediting_502941chr6_127325982_-SINEAluAluJr

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RNA A-to-I editing events in the alternative splicing sites for ECHDC1

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000093144.17.ECHDC1.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000093144.17.ECHDC1.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for ECHDC1

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for ECHDC1

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.
all structure


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The effects of the RNA editing to the miRNA binding sites for ECHDC1

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_502934chr6_127313282_-ENSG00000093144.17ENST00000461239hsa-miR-4772-3p1273132791273132857mer-m8127313278127313300154.00-22.40
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000531967hsa-miR-15b-3p1272896041272896107mer-m8127289603127289624162.00-10.51
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000474289hsa-miR-15b-3p1272896041272896107mer-m8127289603127289624162.00-10.51
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000368295hsa-miR-15b-3p1272896041272896107mer-m8127289603127289624162.00-10.51
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000528402hsa-miR-15b-3p1272896041272896107mer-m8127289603127289624162.00-10.51
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000454591hsa-miR-15b-3p1272896041272896107mer-m8127289603127289624162.00-10.51

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000531967hsa-miR-4795-3p1272896071272896148mer-1a127289607127289628142-4.86
CAediting_502849chr6_127289801_-ENSG00000093144.17ENST00000531967hsa-miR-889-3p1272897971272898048mer-1a127289797127289816153-10.81
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000531967hsa-miR-9441272896051272896117mer-m8127289604127289622147-6.64
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000474289hsa-miR-4795-3p1272896071272896148mer-1a127289607127289628142-4.86
CAediting_502849chr6_127289801_-ENSG00000093144.17ENST00000474289hsa-miR-889-3p1272897971272898048mer-1a127289797127289816153-10.81
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000474289hsa-miR-9441272896051272896117mer-m8127289604127289622147-6.64
CAediting_502850chr6_127290190_-ENSG00000093144.17ENST00000368295hsa-miR-13051272901891272901957mer-m8127290188127290209145-16.45
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000368295hsa-miR-4795-3p1272896071272896148mer-1a127289607127289628142-4.86
CAediting_502849chr6_127289801_-ENSG00000093144.17ENST00000368295hsa-miR-889-3p1272897971272898048mer-1a127289797127289816153-10.81
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000368295hsa-miR-9441272896051272896117mer-m8127289604127289622147-6.64
CAediting_502850chr6_127290190_-ENSG00000093144.17ENST00000528402hsa-miR-13051272901891272901957mer-m8127290188127290209145-16.45
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000528402hsa-miR-4795-3p1272896071272896148mer-1a127289607127289628142-4.86
CAediting_502849chr6_127289801_-ENSG00000093144.17ENST00000528402hsa-miR-889-3p1272897971272898048mer-1a127289797127289816153-10.81
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000528402hsa-miR-9441272896051272896117mer-m8127289604127289622147-6.64
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000454591hsa-miR-4795-3p1272896071272896148mer-1a127289607127289628142-4.86
CAediting_502849chr6_127289801_-ENSG00000093144.17ENST00000454591hsa-miR-889-3p1272897971272898048mer-1a127289797127289816153-10.81
CAediting_502848chr6_127289608_-ENSG00000093144.17ENST00000454591hsa-miR-9441272896051272896117mer-m8127289604127289622147-6.64
CAediting_502850chr6_127290190_-ENSG00000093144.17ENST00000479525hsa-miR-13051272901891272901957mer-m8127290188127290209145-16.45
CAediting_502849chr6_127289801_-ENSG00000093144.17ENST00000479525hsa-miR-889-3p1272897971272898048mer-1a127289797127289816153-10.81
CAediting_502850chr6_127290190_-ENSG00000093144.17ENST00000368291hsa-miR-13051272901891272901957mer-m8127290188127290209145-16.45
CAediting_502849chr6_127289801_-ENSG00000093144.17ENST00000368291hsa-miR-889-3p1272897971272898048mer-1a127289797127289816153-10.81
CAediting_502850chr6_127290190_-ENSG00000093144.17ENST00000368289hsa-miR-13051272901891272901957mer-m8127290188127290209145-16.45
CAediting_502850chr6_127290190_-ENSG00000093144.17ENST00000417628hsa-miR-13051272901891272901957mer-m8127290188127290209145-16.45
CAediting_502850chr6_127290190_-ENSG00000093144.17ENST00000368292hsa-miR-13051272901891272901957mer-m8127290188127290209145-16.45

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_393chr1_1167164_+ENSG00000093144.17ENST00000461239hsa-miR-200b-3p1273134651273134717mer-m8127313464127313483147-12.16
CAediting_1399425chr20_1392958_-ENSG00000093144.17ENST00000531967hsa-miR-6869-5p1272893311272893377mer-m8127289330127289351159-23.43
CAediting_228905chr2_188297554_+ENSG00000093144.17ENST00000531967hsa-miR-561-3p1272887891272887968mer-1a127288789127288807152-13.57
CAediting_1399425chr20_1392958_-ENSG00000093144.17ENST00000474289hsa-miR-6869-5p1272893311272893377mer-m8127289330127289351159-23.43
CAediting_228905chr2_188297554_+ENSG00000093144.17ENST00000474289hsa-miR-561-3p1272887891272887968mer-1a127288789127288807152-13.57
CAediting_1399425chr20_1392958_-ENSG00000093144.17ENST00000368295hsa-miR-6869-5p1272893311272893377mer-m8127289330127289351159-23.43
CAediting_228905chr2_188297554_+ENSG00000093144.17ENST00000368295hsa-miR-561-3p1272887891272887968mer-1a127288789127288807152-13.57
CAediting_1399425chr20_1392958_-ENSG00000093144.17ENST00000528402hsa-miR-6869-5p1272893311272893377mer-m8127289330127289351159-23.43
CAediting_1399425chr20_1392958_-ENSG00000093144.17ENST00000454591hsa-miR-6869-5p1272893311272893377mer-m8127289330127289351159-23.43

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_228905chr2_188297554_+ENSG00000093144.17ENST00000531967hsa-miR-561-3p1272893131272893186mer127289312127289331141-12.14
CAediting_228905chr2_188297554_+ENSG00000093144.17ENST00000474289hsa-miR-561-3p1272893131272893186mer127289312127289331141-12.14
CAediting_228905chr2_188297554_+ENSG00000093144.17ENST00000368295hsa-miR-561-3p1272893131272893186mer127289312127289331141-12.14

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for ECHDC1

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000368295.7nonsense_mediated_decaySoverviewSoverview
ENST00000454591.5protein_codingSoverviewSoverview
ENST00000454859.6protein_codingSoverviewSoverview
ENST00000474289.5protein_codingSoverviewSoverview
ENST00000528402.4protein_codingSoverviewSoverview
ENST00000531967.4protein_codingSoverviewSoverview
ENST00000368291.5protein_codingSoverviewSoverview
ENST00000475319.1retained_intronSoverviewSoverview
ENST00000479525.5nonsense_mediated_decaySoverviewSoverview
ENST00000368289.5protein_codingSoverviewSoverview
ENST00000368292.9nonsense_mediated_decaySoverviewSoverview
ENST00000417628.5nonsense_mediated_decaySoverviewSoverview
ENST00000430841.5protein_codingSoverviewSoverview
ENST00000436638.4protein_codingSoverviewSoverview
ENST00000460558.4protein_codingSoverviewSoverview
ENST00000488087.1processed_transcriptSoverviewSoverview
ENST00000461239.2protein_codingSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_502848ENST00000368295.7chr6_127289608_--465.20-463.10-475.00
CAediting_502849ENST00000368295.7chr6_127289801_--466.80-463.10-475.00
CAediting_502850ENST00000368295.7chr6_127290190_--468.10-463.10-475.00
CAediting_502848ENST00000454591.5chr6_127289608_--379.60-379.40-387.30
CAediting_502849ENST00000454591.5chr6_127289801_--382.50-379.40-387.30
CAediting_502850ENST00000454591.5chr6_127290190_--382.40-379.40-387.30
CAediting_502848ENST00000454859.6chr6_127289608_--596.10-596.00-603.40
CAediting_502849ENST00000454859.6chr6_127289801_--597.20-596.00-603.40
CAediting_502850ENST00000454859.6chr6_127290190_--598.50-596.00-603.40
CAediting_502848ENST00000474289.5chr6_127289608_--650.20-650.10-655.70
CAediting_502849ENST00000474289.5chr6_127289801_--650.20-650.10-655.70
CAediting_502850ENST00000474289.5chr6_127290190_--650.10-650.10-655.70
CAediting_502848ENST00000528402.4chr6_127289608_--362.40-362.30-369.00
CAediting_502849ENST00000528402.4chr6_127289801_--365.40-362.30-369.00
CAediting_502850ENST00000528402.4chr6_127290190_--364.10-362.30-369.00
CAediting_502848ENST00000531967.4chr6_127289608_--642.50-642.40-652.00
CAediting_502849ENST00000531967.4chr6_127289801_--645.80-642.40-652.00
CAediting_502850ENST00000531967.4chr6_127290190_--647.10-642.40-652.00
CAediting_502849ENST00000368291.5chr6_127289801_--376.20-373.10-378.50
CAediting_502850ENST00000368291.5chr6_127290190_--373.70-373.10-378.50
CAediting_502849ENST00000475319.1chr6_127289801_--348.50-347.80-351.70
CAediting_502850ENST00000475319.1chr6_127290190_--351.00-347.80-351.70
CAediting_502849ENST00000479525.5chr6_127289801_--382.40-379.30-384.70
CAediting_502850ENST00000479525.5chr6_127290190_--379.90-379.30-384.70
CAediting_502850ENST00000368289.5chr6_127290190_--258.30-257.40-258.30
CAediting_502850ENST00000368292.9chr6_127290190_--237.70-236.60-237.70
CAediting_502850ENST00000417628.5chr6_127290190_--196.80-196.80-196.80
CAediting_502850ENST00000430841.5chr6_127290190_--278.60-277.70-278.60
CAediting_502850ENST00000436638.4chr6_127290190_--210.00-207.30-210.00
CAediting_502850ENST00000460558.4chr6_127290190_--75.90-74.00-75.90
CAediting_502850ENST00000488087.1chr6_127290190_--96.70-96.50-96.70
CAediting_502934ENST00000461239.2chr6_127313282_--173.20-171.70-173.20

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Relation with ADAR for ECHDC1

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for ECHDC1

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for ECHDC1

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for ECHDC1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ECHDC1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource
ECHDC1C0019193Hepatitis, Toxic1CTD_human
ECHDC1C0025202melanoma1CTD_human
ECHDC1C0860207Drug-Induced Liver Disease1CTD_human
ECHDC1C1262760Hepatitis, Drug-Induced1CTD_human
ECHDC1C3658290Drug-Induced Acute Liver Injury1CTD_human
ECHDC1C4277682Chemical and Drug Induced Liver Injury1CTD_human
ECHDC1C4279912Chemically-Induced Liver Toxicity1CTD_human