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Editing gene: OSGEP (CAeditome ID:55644)

Gene summary for OSGEP

Gene summary

Gene information	Gene symbol	OSGEP
	Gene ID	55644
	Gene name	O-sialoglycoprotein endopeptidase
	Synonyms	GAMOS3\|GCPL1\|KAE1\|OSGEP1\|PRSMG1\|TCS3
	Cytomap	14q11.2
	Type of gene	protein-coding
	Description	probable tRNA N6-adenosine threonylcarbamoyltransferaseN6-L-threonylcarbamoyladenine synthasehOSGEPprobable O-sialoglycoprotein endopeptidaseprobable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPt(6)A synthaset(6)A37 threonylcarbamoylad
	Modification date	20210518
	UniProtAcc	Q9NPF4
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
OSGEP	GO:0002949	Probable tRNA N6-adenosine threonylcarbamoyltransferase	28805828
OSGEP	GO:0005634	Probable tRNA N6-adenosine threonylcarbamoyltransferase	27903914
OSGEP	GO:0005634	Probable tRNA N6-adenosine threonylcarbamoyltransferase	28805828
OSGEP	GO:0005654	Probable tRNA N6-adenosine threonylcarbamoyltransferase	0000052
OSGEP	GO:0005737	Probable tRNA N6-adenosine threonylcarbamoyltransferase	28805828
OSGEP	GO:0005886	Probable tRNA N6-adenosine threonylcarbamoyltransferase	0000052
OSGEP	GO:0016607	Probable tRNA N6-adenosine threonylcarbamoyltransferase	0000052
OSGEP	GO:0000408	Probable tRNA N6-adenosine threonylcarbamoyltransferase	27903914
OSGEP	GO:0000408	Probable tRNA N6-adenosine threonylcarbamoyltransferase	28805828

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RNA A-to-I events for OSGEP

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000092094.9

RNA A-to-I editing events in Cancer.

CAediting_975616(20446474, -), CAediting_975617(20446534, -), CAediting_975618(20446552, -), CAediting_975619(20446628, -), CAediting_975620(20446692, -), CAediting_975621(20446938, -), CAediting_975622(20446942, -), CAediting_975623(20446943, -), CAediting_975624(20449668, -), CAediting_975625(20449674, -), CAediting_975626(20449676, -), CAediting_975627(20449703, -), CAediting_975628(20449706, -), CAediting_975629(20449713, -), CAediting_975630(20449719, -), CAediting_975631(20449733, -), CAediting_975632(20449756, -), CAediting_975633(20449761, -), CAediting_975634(20449765, -), CAediting_975635(20449778, -), CAediting_975636(20449792, -), CAediting_975637(20449822, -), CAediting_975638(20449826, -), CAediting_975639(20449830, -), CAediting_975640(20449843, -), CAediting_975641(20449851, -), CAediting_975642(20449854, -), CAediting_975643(20449857, -), CAediting_975644(20449859, -), CAediting_975645(20449869, -), CAediting_975646(20449873, -), CAediting_975647(20449883, -), CAediting_975648(20449885, -), CAediting_975649(20449891, -), CAediting_975650(20449899, -), CAediting_975651(20449900, -), CAediting_975652(20449906, -), CAediting_975653(20449926, -), CAediting_975654(20449936, -), CAediting_975655(20450042, -), CAediting_975656(20450043, -), CAediting_975657(20450044, -), CAediting_975658(20450077, -), CAediting_975659(20450079, -), CAediting_975660(20450106, -), CAediting_975661(20450109, -), CAediting_975662(20450116, -), CAediting_975663(20450129, -), CAediting_975664(20450141, -), CAediting_975665(20450150, -), CAediting_975666(20450155, -), CAediting_975667(20450176, -), CAediting_975668(20450181, -), CAediting_975669(20450182, -), CAediting_975670(20450274, -), CAediting_975671(20450843, -), CAediting_975672(20450856, -), CAediting_975673(20450868, -), CAediting_975674(20450869, -), CAediting_975675(20450896, -), CAediting_975676(20450901, -), CAediting_975677(20450933, -), CAediting_975678(20450947, -), CAediting_975679(20450950, -), CAediting_975680(20450965, -), CAediting_975681(20450992, -), CAediting_975682(20451002, -), CAediting_975683(20451005, -), CAediting_975684(20451025, -), CAediting_975685(20451046, -), CAediting_975686(20451047, -), CAediting_975687(20451062, -), CAediting_975688(20451063, -), CAediting_975689(20451067, -), CAediting_975690(20451083, -), CAediting_975691(20451090, -), CAediting_975692(20451113, -), CAediting_975693(20451121, -), CAediting_975694(20451125, -), CAediting_975695(20452052, -), CAediting_975696(20452573, -), CAediting_975697(20452803, -), CAediting_975698(20452822, -), CAediting_975699(20452835, -), CAediting_975700(20452839, -), CAediting_975701(20452843, -), CAediting_975702(20453478, -), CAediting_975703(20453499, -), CAediting_975704(20453503, -), CAediting_975705(20453504, -), CAediting_975706(20453530, -), CAediting_975707(20453534, -), CAediting_975708(20453535, -), CAediting_975709(20453538, -), CAediting_975710(20453541, -), CAediting_975711(20453543, -), CAediting_975712(20453544, -), CAediting_975713(20453546, -), CAediting_975714(20453547, -), CAediting_975715(20453600, -), CAediting_975716(20453610, -), CAediting_975717(20453777, -), CAediting_975718(20453778, -), CAediting_975719(20453853, -), CAediting_975720(20453856, -), CAediting_975721(20453870, -), CAediting_975722(20453871, -),

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RNA editing positional annotations for OSGEP using Annovar

Protein coding RNA editing(s).

CAeditome ID	Position	Variant type	ENST	NTchange	AAchange	SIFT_score	Polyphen2_HVAR_score	PROVEAN_pred
CAediting_975695	chr14_20452052_-	nonsynonymous SNV	ENST00000206542.7	c.A333G	p.I111M	D	D	D
CAediting_975695	chr14_20452052_-	nonsynonymous SNV	ENST00000553640.3	c.A333G	p.I111M	D	D	D

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_975616	chr14_20446474_-	ncRNA_exonic
CAediting_975617	chr14_20446534_-	ncRNA_exonic
CAediting_975618	chr14_20446552_-	ncRNA_exonic
CAediting_975619	chr14_20446628_-	ncRNA_exonic
CAediting_975620	chr14_20446692_-	ncRNA_exonic
CAediting_975621	chr14_20446938_-	ncRNA_exonic
CAediting_975622	chr14_20446942_-	ncRNA_exonic
CAediting_975623	chr14_20446943_-	ncRNA_exonic
CAediting_975624	chr14_20449668_-	ncRNA_exonic
CAediting_975625	chr14_20449674_-	ncRNA_exonic
CAediting_975626	chr14_20449676_-	ncRNA_exonic
CAediting_975627	chr14_20449703_-	ncRNA_exonic
CAediting_975628	chr14_20449706_-	ncRNA_exonic
CAediting_975629	chr14_20449713_-	ncRNA_exonic
CAediting_975630	chr14_20449719_-	ncRNA_exonic
CAediting_975631	chr14_20449733_-	ncRNA_exonic
CAediting_975632	chr14_20449756_-	ncRNA_exonic
CAediting_975633	chr14_20449761_-	ncRNA_exonic
CAediting_975634	chr14_20449765_-	ncRNA_exonic
CAediting_975635	chr14_20449778_-	ncRNA_exonic
CAediting_975636	chr14_20449792_-	ncRNA_exonic
CAediting_975637	chr14_20449822_-	ncRNA_exonic
CAediting_975638	chr14_20449826_-	ncRNA_exonic
CAediting_975639	chr14_20449830_-	ncRNA_exonic
CAediting_975640	chr14_20449843_-	ncRNA_exonic
CAediting_975641	chr14_20449851_-	ncRNA_exonic
CAediting_975642	chr14_20449854_-	ncRNA_exonic
CAediting_975643	chr14_20449857_-	ncRNA_exonic
CAediting_975644	chr14_20449859_-	ncRNA_exonic
CAediting_975645	chr14_20449869_-	ncRNA_exonic
CAediting_975646	chr14_20449873_-	ncRNA_exonic
CAediting_975647	chr14_20449883_-	ncRNA_exonic
CAediting_975648	chr14_20449885_-	ncRNA_exonic
CAediting_975649	chr14_20449891_-	ncRNA_exonic
CAediting_975650	chr14_20449899_-	ncRNA_exonic
CAediting_975651	chr14_20449900_-	ncRNA_exonic
CAediting_975652	chr14_20449906_-	ncRNA_exonic
CAediting_975653	chr14_20449926_-	ncRNA_exonic
CAediting_975654	chr14_20449936_-	ncRNA_exonic
CAediting_975655	chr14_20450042_-	ncRNA_exonic
CAediting_975656	chr14_20450043_-	ncRNA_exonic
CAediting_975657	chr14_20450044_-	ncRNA_exonic
CAediting_975658	chr14_20450077_-	ncRNA_exonic
CAediting_975659	chr14_20450079_-	ncRNA_exonic
CAediting_975660	chr14_20450106_-	ncRNA_exonic
CAediting_975661	chr14_20450109_-	ncRNA_exonic
CAediting_975662	chr14_20450116_-	ncRNA_exonic
CAediting_975663	chr14_20450129_-	ncRNA_exonic
CAediting_975664	chr14_20450141_-	ncRNA_exonic
CAediting_975665	chr14_20450150_-	ncRNA_exonic
CAediting_975666	chr14_20450155_-	ncRNA_exonic
CAediting_975667	chr14_20450176_-	ncRNA_exonic
CAediting_975668	chr14_20450181_-	ncRNA_exonic
CAediting_975669	chr14_20450182_-	ncRNA_exonic
CAediting_975670	chr14_20450274_-	ncRNA_exonic
CAediting_975671	chr14_20450843_-	ncRNA_exonic
CAediting_975672	chr14_20450856_-	ncRNA_exonic
CAediting_975673	chr14_20450868_-	ncRNA_exonic
CAediting_975674	chr14_20450869_-	ncRNA_exonic
CAediting_975675	chr14_20450896_-	ncRNA_intronic
CAediting_975676	chr14_20450901_-	ncRNA_intronic
CAediting_975677	chr14_20450933_-	ncRNA_intronic
CAediting_975678	chr14_20450947_-	ncRNA_intronic
CAediting_975679	chr14_20450950_-	ncRNA_intronic
CAediting_975680	chr14_20450965_-	ncRNA_intronic
CAediting_975681	chr14_20450992_-	ncRNA_intronic
CAediting_975682	chr14_20451002_-	ncRNA_intronic
CAediting_975683	chr14_20451005_-	ncRNA_intronic
CAediting_975684	chr14_20451025_-	ncRNA_intronic
CAediting_975685	chr14_20451046_-	ncRNA_intronic
CAediting_975686	chr14_20451047_-	ncRNA_intronic
CAediting_975687	chr14_20451062_-	ncRNA_intronic
CAediting_975688	chr14_20451063_-	ncRNA_intronic
CAediting_975689	chr14_20451067_-	ncRNA_intronic
CAediting_975690	chr14_20451083_-	ncRNA_intronic
CAediting_975691	chr14_20451090_-	ncRNA_intronic
CAediting_975692	chr14_20451113_-	ncRNA_intronic
CAediting_975693	chr14_20451121_-	ncRNA_intronic
CAediting_975694	chr14_20451125_-	ncRNA_intronic
CAediting_975695	chr14_20452052_-	exonic
CAediting_975696	chr14_20452573_-	ncRNA_intronic
CAediting_975697	chr14_20452803_-	ncRNA_intronic
CAediting_975698	chr14_20452822_-	ncRNA_intronic
CAediting_975699	chr14_20452835_-	ncRNA_intronic
CAediting_975700	chr14_20452839_-	ncRNA_intronic
CAediting_975701	chr14_20452843_-	ncRNA_intronic
CAediting_975702	chr14_20453478_-	ncRNA_intronic
CAediting_975703	chr14_20453499_-	ncRNA_intronic
CAediting_975704	chr14_20453503_-	ncRNA_intronic
CAediting_975705	chr14_20453504_-	ncRNA_intronic
CAediting_975706	chr14_20453530_-	ncRNA_intronic
CAediting_975707	chr14_20453534_-	ncRNA_intronic
CAediting_975708	chr14_20453535_-	ncRNA_intronic
CAediting_975709	chr14_20453538_-	ncRNA_intronic
CAediting_975710	chr14_20453541_-	ncRNA_intronic
CAediting_975711	chr14_20453543_-	ncRNA_intronic
CAediting_975712	chr14_20453544_-	ncRNA_intronic
CAediting_975713	chr14_20453546_-	ncRNA_intronic
CAediting_975714	chr14_20453547_-	ncRNA_intronic
CAediting_975715	chr14_20453600_-	ncRNA_intronic
CAediting_975716	chr14_20453610_-	ncRNA_intronic
CAediting_975717	chr14_20453777_-	ncRNA_intronic
CAediting_975718	chr14_20453778_-	ncRNA_intronic
CAediting_975719	chr14_20453853_-	ncRNA_intronic
CAediting_975720	chr14_20453856_-	ncRNA_intronic
CAediting_975721	chr14_20453870_-	ncRNA_intronic
CAediting_975722	chr14_20453871_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_975616	chr14_20446474_-	SINE	Alu	AluJr
CAediting_975617	chr14_20446534_-	SINE	Alu	AluJr
CAediting_975618	chr14_20446552_-	SINE	Alu	AluJr
CAediting_975619	chr14_20446628_-	SINE	Alu	AluJr
CAediting_975620	chr14_20446692_-	SINE	Alu	AluJr
CAediting_975621	chr14_20446938_-	SINE	Alu	FLAM_C
CAediting_975622	chr14_20446942_-	SINE	Alu	FLAM_C
CAediting_975623	chr14_20446943_-	SINE	Alu	FLAM_C
CAediting_975624	chr14_20449668_-	SINE	Alu	AluJr
CAediting_975625	chr14_20449674_-	SINE	Alu	AluJr
CAediting_975626	chr14_20449676_-	SINE	Alu	AluJr
CAediting_975627	chr14_20449703_-	SINE	Alu	AluJr
CAediting_975628	chr14_20449706_-	SINE	Alu	AluJr
CAediting_975629	chr14_20449713_-	SINE	Alu	AluJr
CAediting_975630	chr14_20449719_-	SINE	Alu	AluJr
CAediting_975631	chr14_20449733_-	SINE	Alu	AluJr
CAediting_975632	chr14_20449756_-	SINE	Alu	AluJr
CAediting_975633	chr14_20449761_-	SINE	Alu	AluJr
CAediting_975634	chr14_20449765_-	SINE	Alu	AluJr
CAediting_975635	chr14_20449778_-	SINE	Alu	AluJr
CAediting_975636	chr14_20449792_-	SINE	Alu	AluJr
CAediting_975637	chr14_20449822_-	SINE	Alu	AluJr
CAediting_975638	chr14_20449826_-	SINE	Alu	AluJr
CAediting_975639	chr14_20449830_-	SINE	Alu	AluJr
CAediting_975640	chr14_20449843_-	SINE	Alu	AluJr
CAediting_975641	chr14_20449851_-	SINE	Alu	AluJr
CAediting_975642	chr14_20449854_-	SINE	Alu	AluJr
CAediting_975643	chr14_20449857_-	SINE	Alu	AluJr
CAediting_975644	chr14_20449859_-	SINE	Alu	AluJr
CAediting_975645	chr14_20449869_-	SINE	Alu	AluJr
CAediting_975646	chr14_20449873_-	SINE	Alu	AluJr
CAediting_975647	chr14_20449883_-	SINE	Alu	AluJr
CAediting_975648	chr14_20449885_-	SINE	Alu	AluJr
CAediting_975649	chr14_20449891_-	SINE	Alu	AluJr
CAediting_975650	chr14_20449899_-	SINE	Alu	AluJr
CAediting_975651	chr14_20449900_-	SINE	Alu	AluJr
CAediting_975652	chr14_20449906_-	SINE	Alu	AluJr
CAediting_975655	chr14_20450042_-	SINE	Alu	AluSx1
CAediting_975656	chr14_20450043_-	SINE	Alu	AluSx1
CAediting_975657	chr14_20450044_-	SINE	Alu	AluSx1
CAediting_975658	chr14_20450077_-	SINE	Alu	AluSx1
CAediting_975659	chr14_20450079_-	SINE	Alu	AluSx1
CAediting_975660	chr14_20450106_-	SINE	Alu	AluSx1
CAediting_975661	chr14_20450109_-	SINE	Alu	AluSx1
CAediting_975662	chr14_20450116_-	SINE	Alu	AluSx1
CAediting_975663	chr14_20450129_-	SINE	Alu	AluSx1
CAediting_975664	chr14_20450141_-	SINE	Alu	AluSx1
CAediting_975665	chr14_20450150_-	SINE	Alu	AluSx1
CAediting_975666	chr14_20450155_-	SINE	Alu	AluSx1
CAediting_975667	chr14_20450176_-	SINE	Alu	AluSx1
CAediting_975668	chr14_20450181_-	SINE	Alu	AluSx1
CAediting_975669	chr14_20450182_-	SINE	Alu	AluSx1
CAediting_975671	chr14_20450843_-	SINE	Alu	AluSq2
CAediting_975672	chr14_20450856_-	SINE	Alu	AluSq2
CAediting_975673	chr14_20450868_-	SINE	Alu	AluSq2
CAediting_975674	chr14_20450869_-	SINE	Alu	AluSq2
CAediting_975675	chr14_20450896_-	SINE	Alu	AluSq2
CAediting_975676	chr14_20450901_-	SINE	Alu	AluSq2
CAediting_975677	chr14_20450933_-	SINE	Alu	AluSq2
CAediting_975678	chr14_20450947_-	SINE	Alu	AluSq2
CAediting_975679	chr14_20450950_-	SINE	Alu	AluSq2
CAediting_975680	chr14_20450965_-	SINE	Alu	AluSq2
CAediting_975681	chr14_20450992_-	SINE	Alu	AluSq2
CAediting_975682	chr14_20451002_-	SINE	Alu	AluSq2
CAediting_975683	chr14_20451005_-	SINE	Alu	AluSq2
CAediting_975684	chr14_20451025_-	SINE	Alu	AluSq2
CAediting_975685	chr14_20451046_-	SINE	Alu	AluSq2
CAediting_975686	chr14_20451047_-	SINE	Alu	AluSq2
CAediting_975687	chr14_20451062_-	SINE	Alu	AluSq2
CAediting_975688	chr14_20451063_-	SINE	Alu	AluSq2
CAediting_975689	chr14_20451067_-	SINE	Alu	AluSq2
CAediting_975690	chr14_20451083_-	SINE	Alu	AluSq2
CAediting_975691	chr14_20451090_-	SINE	Alu	AluSq2
CAediting_975692	chr14_20451113_-	SINE	Alu	AluSq2
CAediting_975693	chr14_20451121_-	SINE	Alu	AluSq2
CAediting_975694	chr14_20451125_-	SINE	Alu	AluSq2
CAediting_975697	chr14_20452803_-	SINE	Alu	AluSx4
CAediting_975698	chr14_20452822_-	SINE	Alu	AluSx4
CAediting_975699	chr14_20452835_-	SINE	Alu	AluSx4
CAediting_975700	chr14_20452839_-	SINE	Alu	AluSx4
CAediting_975701	chr14_20452843_-	SINE	Alu	AluSx4
CAediting_975702	chr14_20453478_-	SINE	Alu	AluSp
CAediting_975703	chr14_20453499_-	SINE	Alu	AluSp
CAediting_975704	chr14_20453503_-	SINE	Alu	AluSp
CAediting_975705	chr14_20453504_-	SINE	Alu	AluSp
CAediting_975706	chr14_20453530_-	SINE	Alu	AluSp
CAediting_975707	chr14_20453534_-	SINE	Alu	AluSp
CAediting_975708	chr14_20453535_-	SINE	Alu	AluSp
CAediting_975709	chr14_20453538_-	SINE	Alu	AluSp
CAediting_975710	chr14_20453541_-	SINE	Alu	AluSp
CAediting_975711	chr14_20453543_-	SINE	Alu	AluSp
CAediting_975712	chr14_20453544_-	SINE	Alu	AluSp
CAediting_975713	chr14_20453546_-	SINE	Alu	AluSp
CAediting_975714	chr14_20453547_-	SINE	Alu	AluSp
CAediting_975715	chr14_20453600_-	SINE	Alu	AluSp
CAediting_975716	chr14_20453610_-	SINE	Alu	AluSp
CAediting_975717	chr14_20453777_-	SINE	Alu	AluSx
CAediting_975718	chr14_20453778_-	SINE	Alu	AluSx
CAediting_975719	chr14_20453853_-	SINE	Alu	AluSx
CAediting_975720	chr14_20453856_-	SINE	Alu	AluSx
CAediting_975721	chr14_20453870_-	SINE	Alu	AluSx
CAediting_975722	chr14_20453871_-	SINE	Alu	AluSx

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RNA A-to-I editing events in the alternative splicing sites for OSGEP

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000092094.9.OSGEP.

Correlation between RNA A-to-I editing and PSI for ENSG00000092094.9.OSGEP.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for OSGEP

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for OSGEP

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for OSGEP

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_1160181	chr17_7017644_-	ENSG00000092094.9	ENST00000555223	hsa-miR-195-3p	20448979	20448986	8mer-1a	20448979	20448998	155	-14.43

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for OSGEP

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for OSGEP

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
LGG	CAediting_975627	chr14_20449703_-	.	.	0.0179746984171553	0.290490964404866	.	.
LGG	CAediting_975630	chr14_20449719_-	.	.	0.000547670873083925	0.454949183355417	.	.
LGG	CAediting_975631	chr14_20449733_-	.	.	0.00521416773921139	0.189885376317933	.	.
THCA	CAediting_975631	chr14_20449733_-	0.00327855242201743	0.308399920781306	.	.	.	.
LGG	CAediting_975645	chr14_20449869_-	.	.	.	.	0.0451605679877401	0.121568179017282
BRCA	CAediting_975645	chr14_20449869_-	0.0199227963556186	0.203980094730053	.	.	.	.
BRCA	CAediting_975668	chr14_20450181_-	.	.	.	.	0.0128013042053799	0.336668870756216
BRCA	CAediting_975669	chr14_20450182_-	.	.	.	.	0.000687839162098971	0.34937464193402

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Relation with cancer stages for OSGEP

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
KIRC	pathologic_stage	CAediting_975645	chr14_20449869_-	0.0186379672338406	0.23974813779817
THCA	pathologic_stage	CAediting_975668	chr14_20450181_-	0.00111993480832099	-0.392377464904723
THCA	pathologic_stage	CAediting_975669	chr14_20450182_-	0.00628144006384293	-0.292482931589826

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Relation with survival for OSGEP

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for OSGEP

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for OSGEP

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	# pubmeds	Source
OSGEP	C4540266	GALLOWAY-MOWAT SYNDROME 3	2	GENOMICS_ENGLAND;UNIPROT
OSGEP	C0795949	Galloway Mowat syndrome	1	CTD_human;ORPHANET
OSGEP	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene