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Editing gene: SMPD4 (CAeditome ID:55627)

Gene summary for SMPD4

Gene summary

Gene information	Gene symbol	SMPD4
	Gene ID	55627
	Gene name	sphingomyelin phosphodiesterase 4
	Synonyms	NEDMABA\|NEDMEBA\|NET13\|NSMASE-3\|NSMASE3\|SKNY
	Cytomap	2q21.1
	Type of gene	protein-coding
	Description	sphingomyelin phosphodiesterase 4neutral sphingomyelinase 3neutral sphingomyelinase IIIsphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
	Modification date	20210518
	UniProtAcc	Q9NXE4
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
SMPD4	GO:0050290	Sphingomyelin phosphodiesterase 4	16517606
SMPD4	GO:0050290	Sphingomyelin phosphodiesterase 4	25180167
SMPD4	GO:0006685	Sphingomyelin phosphodiesterase 4	16517606
SMPD4	GO:0006685	Sphingomyelin phosphodiesterase 4	25180167
SMPD4	GO:0046475	Sphingomyelin phosphodiesterase 4	16517606
SMPD4	GO:0046513	Sphingomyelin phosphodiesterase 4	16517606
SMPD4	GO:0046513	Sphingomyelin phosphodiesterase 4	25180167
SMPD4	GO:0071356	Sphingomyelin phosphodiesterase 4	16517606
SMPD4	GO:0005640	Sphingomyelin phosphodiesterase 4	31495489
SMPD4	GO:0005783	Sphingomyelin phosphodiesterase 4	16517606
SMPD4	GO:0005783	Sphingomyelin phosphodiesterase 4	18505924
SMPD4	GO:0005783	Sphingomyelin phosphodiesterase 4	31495489
SMPD4	GO:0005794	Sphingomyelin phosphodiesterase 4	16517606
SMPD4	GO:0005802	Sphingomyelin phosphodiesterase 4	16517606

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RNA A-to-I events for SMPD4

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000136699.18

RNA A-to-I editing events in Cancer.

CAediting_212525(130152066, -), CAediting_212526(130157875, -), CAediting_212527(130157884, -), CAediting_212528(130157896, -), CAediting_212529(130157897, -), CAediting_212530(130157898, -), CAediting_212531(130157940, -), CAediting_212532(130157941, -), CAediting_212533(130157966, -), CAediting_212534(130157970, -), CAediting_212535(130157972, -), CAediting_212536(130157991, -), CAediting_212537(130157992, -), CAediting_212538(130157996, -), CAediting_212539(130158000, -), CAediting_212540(130158002, -), CAediting_212541(130158005, -), CAediting_212542(130158008, -), CAediting_212543(130158016, -), CAediting_212544(130158024, -), CAediting_212545(130158031, -), CAediting_212546(130158053, -), CAediting_212547(130158057, -), CAediting_212548(130158058, -), CAediting_212549(130158071, -), CAediting_212550(130158072, -), CAediting_212551(130158078, -), CAediting_212552(130158083, -), CAediting_212553(130158096, -), CAediting_212554(130158114, -), CAediting_212555(130158118, -), CAediting_212556(130158124, -), CAediting_212557(130158131, -), CAediting_212558(130158134, -), CAediting_212559(130158135, -), CAediting_212560(130158335, -), CAediting_212561(130158385, -), CAediting_212562(130158390, -), CAediting_212563(130158394, -), CAediting_212564(130158407, -), CAediting_212565(130158413, -), CAediting_212566(130158414, -), CAediting_212567(130158422, -), CAediting_212568(130158428, -), CAediting_212569(130158432, -), CAediting_212570(130158438, -), CAediting_212571(130158441, -), CAediting_212572(130158445, -), CAediting_212573(130158449, -), CAediting_212574(130158461, -), CAediting_212575(130158465, -), CAediting_212576(130158481, -), CAediting_212577(130158484, -), CAediting_212578(130158485, -), CAediting_212579(130158486, -), CAediting_212580(130158487, -), CAediting_212581(130158488, -), CAediting_212582(130158490, -), CAediting_212583(130158491, -), CAediting_212584(130158492, -), CAediting_212585(130158503, -), CAediting_212586(130158508, -), CAediting_212587(130158516, -), CAediting_212588(130158524, -), CAediting_212589(130158552, -), CAediting_212590(130158560, -), CAediting_212591(130158568, -), CAediting_212592(130159007, -), CAediting_212593(130159008, -), CAediting_212594(130159010, -), CAediting_212595(130159011, -), CAediting_212596(130159012, -), CAediting_212597(130159027, -), CAediting_212598(130159029, -), CAediting_212599(130159033, -), CAediting_212600(130159035, -), CAediting_212601(130159049, -), CAediting_212602(130159054, -), CAediting_212603(130159062, -), CAediting_212604(130159067, -), CAediting_212605(130159071, -), CAediting_212606(130159078, -), CAediting_212607(130159080, -), CAediting_212608(130159084, -), CAediting_212609(130159092, -), CAediting_212610(130159093, -), CAediting_212611(130159108, -), CAediting_212612(130159110, -), CAediting_212613(130159123, -), CAediting_212614(130159127, -), CAediting_212615(130159161, -), CAediting_212616(130159164, -), CAediting_212617(130159165, -), CAediting_212618(130159166, -), CAediting_212619(130159167, -), CAediting_212620(130159170, -), CAediting_212621(130159172, -), CAediting_212622(130159173, -), CAediting_212623(130159176, -), CAediting_212624(130159188, -), CAediting_212625(130159196, -), CAediting_212626(130159208, -), CAediting_212627(130159211, -), CAediting_212628(130159213, -), CAediting_212629(130159219, -), CAediting_212630(130159227, -), CAediting_212631(130159241, -), CAediting_212632(130159259, -), CAediting_212633(130159262, -), CAediting_212634(130159267, -), CAediting_212635(130159268, -), CAediting_212636(130159290, -), CAediting_212637(130159294, -), CAediting_212638(130159382, -), CAediting_212639(130159394, -), CAediting_212640(130159395, -), CAediting_212641(130159421, -), CAediting_212642(130159422, -), CAediting_212643(130159434, -), CAediting_212644(130159435, -), CAediting_212645(130159436, -), CAediting_212646(130159447, -), CAediting_212647(130159456, -), CAediting_212648(130159459, -), CAediting_212649(130159471, -), CAediting_212650(130159473, -), CAediting_212651(130159482, -), CAediting_212652(130159490, -), CAediting_212653(130159491, -), CAediting_212654(130159503, -), CAediting_212655(130159510, -), CAediting_212656(130159514, -), CAediting_212657(130159516, -), CAediting_212658(130159526, -), CAediting_212659(130159529, -), CAediting_212660(130159538, -), CAediting_212661(130159555, -), CAediting_212662(130159556, -), CAediting_212663(130159562, -), CAediting_212664(130159569, -), CAediting_212665(130159581, -), CAediting_212666(130159596, -), CAediting_212667(130159605, -), CAediting_212668(130159624, -), CAediting_212669(130159636, -), CAediting_212670(130165849, -), CAediting_212671(130166143, -), CAediting_212672(130166152, -), CAediting_212673(130167153, -), CAediting_212674(130167186, -), CAediting_212675(130167193, -), CAediting_212676(130167194, -), CAediting_212677(130167197, -), CAediting_212678(130167213, -), CAediting_212679(130167217, -), CAediting_212680(130167249, -), CAediting_212681(130167253, -), CAediting_212682(130167258, -), CAediting_212683(130167269, -), CAediting_212684(130167285, -), CAediting_212685(130167289, -), CAediting_212686(130167290, -), CAediting_212687(130167291, -), CAediting_212688(130167294, -), CAediting_212689(130167363, -), CAediting_212690(130167395, -), CAediting_212691(130167983, -), CAediting_212692(130167984, -), CAediting_212693(130167998, -), CAediting_212694(130168084, -), CAediting_212695(130168090, -), CAediting_212696(130168094, -), CAediting_212697(130168098, -), CAediting_212698(130168302, -), CAediting_212699(130168324, -), CAediting_212700(130168365, -), CAediting_212701(130168367, -), CAediting_212702(130168380, -), CAediting_212703(130168562, -), CAediting_212704(130168592, -), CAediting_212705(130168671, -), CAediting_212706(130168695, -), CAediting_212707(130168784, -), CAediting_212708(130168845, -), CAediting_212709(130168854, -), CAediting_212710(130168859, -), CAediting_212711(130168860, -), CAediting_212712(130168882, -), CAediting_212713(130168896, -), CAediting_212714(130169603, -), CAediting_212715(130169680, -), CAediting_212716(130169696, -), CAediting_212717(130170656, -), CAediting_212718(130170681, -), CAediting_212719(130170961, -), CAediting_212720(130171201, -), CAediting_212721(130171229, -), CAediting_212722(130171233, -), CAediting_212723(130171269, -), CAediting_212724(130171278, -), CAediting_212725(130171280, -), CAediting_212726(130171281, -), CAediting_212727(130171282, -), CAediting_212728(130171283, -), CAediting_212729(130171284, -), CAediting_212730(130171287, -), CAediting_212731(130171311, -), CAediting_212732(130171326, -), CAediting_212733(130177245, -), CAediting_212734(130177298, -), CAediting_212735(130177301, -),

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RNA editing positional annotations for SMPD4 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_212525	chr2_130152066_-	ncRNA_exonic
CAediting_212526	chr2_130157875_-	ncRNA_exonic
CAediting_212527	chr2_130157884_-	ncRNA_exonic
CAediting_212528	chr2_130157896_-	ncRNA_exonic
CAediting_212529	chr2_130157897_-	ncRNA_exonic
CAediting_212530	chr2_130157898_-	ncRNA_exonic
CAediting_212531	chr2_130157940_-	ncRNA_exonic
CAediting_212532	chr2_130157941_-	ncRNA_exonic
CAediting_212533	chr2_130157966_-	ncRNA_intronic
CAediting_212534	chr2_130157970_-	ncRNA_intronic
CAediting_212535	chr2_130157972_-	ncRNA_intronic
CAediting_212536	chr2_130157991_-	ncRNA_intronic
CAediting_212537	chr2_130157992_-	ncRNA_intronic
CAediting_212538	chr2_130157996_-	ncRNA_intronic
CAediting_212539	chr2_130158000_-	ncRNA_intronic
CAediting_212540	chr2_130158002_-	ncRNA_intronic
CAediting_212541	chr2_130158005_-	ncRNA_intronic
CAediting_212542	chr2_130158008_-	ncRNA_intronic
CAediting_212543	chr2_130158016_-	ncRNA_intronic
CAediting_212544	chr2_130158024_-	ncRNA_intronic
CAediting_212545	chr2_130158031_-	ncRNA_intronic
CAediting_212546	chr2_130158053_-	ncRNA_intronic
CAediting_212547	chr2_130158057_-	ncRNA_intronic
CAediting_212548	chr2_130158058_-	ncRNA_intronic
CAediting_212549	chr2_130158071_-	ncRNA_intronic
CAediting_212550	chr2_130158072_-	ncRNA_intronic
CAediting_212551	chr2_130158078_-	ncRNA_intronic
CAediting_212552	chr2_130158083_-	ncRNA_intronic
CAediting_212553	chr2_130158096_-	ncRNA_intronic
CAediting_212554	chr2_130158114_-	ncRNA_intronic
CAediting_212555	chr2_130158118_-	ncRNA_intronic
CAediting_212556	chr2_130158124_-	ncRNA_intronic
CAediting_212557	chr2_130158131_-	ncRNA_intronic
CAediting_212558	chr2_130158134_-	ncRNA_intronic
CAediting_212559	chr2_130158135_-	ncRNA_intronic
CAediting_212560	chr2_130158335_-	ncRNA_intronic
CAediting_212561	chr2_130158385_-	ncRNA_intronic
CAediting_212562	chr2_130158390_-	ncRNA_intronic
CAediting_212563	chr2_130158394_-	ncRNA_intronic
CAediting_212564	chr2_130158407_-	ncRNA_intronic
CAediting_212565	chr2_130158413_-	ncRNA_intronic
CAediting_212566	chr2_130158414_-	ncRNA_intronic
CAediting_212567	chr2_130158422_-	ncRNA_intronic
CAediting_212568	chr2_130158428_-	ncRNA_intronic
CAediting_212569	chr2_130158432_-	ncRNA_intronic
CAediting_212570	chr2_130158438_-	ncRNA_intronic
CAediting_212571	chr2_130158441_-	ncRNA_intronic
CAediting_212572	chr2_130158445_-	ncRNA_intronic
CAediting_212573	chr2_130158449_-	ncRNA_intronic
CAediting_212574	chr2_130158461_-	ncRNA_intronic
CAediting_212575	chr2_130158465_-	ncRNA_intronic
CAediting_212576	chr2_130158481_-	ncRNA_intronic
CAediting_212577	chr2_130158484_-	ncRNA_intronic
CAediting_212578	chr2_130158485_-	ncRNA_intronic
CAediting_212579	chr2_130158486_-	ncRNA_intronic
CAediting_212580	chr2_130158487_-	ncRNA_intronic
CAediting_212581	chr2_130158488_-	ncRNA_intronic
CAediting_212582	chr2_130158490_-	ncRNA_intronic
CAediting_212583	chr2_130158491_-	ncRNA_intronic
CAediting_212584	chr2_130158492_-	ncRNA_intronic
CAediting_212585	chr2_130158503_-	ncRNA_intronic
CAediting_212586	chr2_130158508_-	ncRNA_intronic
CAediting_212587	chr2_130158516_-	ncRNA_intronic
CAediting_212588	chr2_130158524_-	ncRNA_intronic
CAediting_212589	chr2_130158552_-	ncRNA_intronic
CAediting_212590	chr2_130158560_-	ncRNA_intronic
CAediting_212591	chr2_130158568_-	ncRNA_intronic
CAediting_212592	chr2_130159007_-	ncRNA_intronic
CAediting_212593	chr2_130159008_-	ncRNA_intronic
CAediting_212594	chr2_130159010_-	ncRNA_intronic
CAediting_212595	chr2_130159011_-	ncRNA_intronic
CAediting_212596	chr2_130159012_-	ncRNA_intronic
CAediting_212597	chr2_130159027_-	ncRNA_intronic
CAediting_212598	chr2_130159029_-	ncRNA_intronic
CAediting_212599	chr2_130159033_-	ncRNA_intronic
CAediting_212600	chr2_130159035_-	ncRNA_intronic
CAediting_212601	chr2_130159049_-	ncRNA_intronic
CAediting_212602	chr2_130159054_-	ncRNA_intronic
CAediting_212603	chr2_130159062_-	ncRNA_intronic
CAediting_212604	chr2_130159067_-	ncRNA_intronic
CAediting_212605	chr2_130159071_-	ncRNA_intronic
CAediting_212606	chr2_130159078_-	ncRNA_intronic
CAediting_212607	chr2_130159080_-	ncRNA_intronic
CAediting_212608	chr2_130159084_-	ncRNA_intronic
CAediting_212609	chr2_130159092_-	ncRNA_intronic
CAediting_212610	chr2_130159093_-	ncRNA_intronic
CAediting_212611	chr2_130159108_-	ncRNA_intronic
CAediting_212612	chr2_130159110_-	ncRNA_intronic
CAediting_212613	chr2_130159123_-	ncRNA_intronic
CAediting_212614	chr2_130159127_-	ncRNA_intronic
CAediting_212615	chr2_130159161_-	ncRNA_intronic
CAediting_212616	chr2_130159164_-	ncRNA_intronic
CAediting_212617	chr2_130159165_-	ncRNA_intronic
CAediting_212618	chr2_130159166_-	ncRNA_intronic
CAediting_212619	chr2_130159167_-	ncRNA_intronic
CAediting_212620	chr2_130159170_-	ncRNA_intronic
CAediting_212621	chr2_130159172_-	ncRNA_intronic
CAediting_212622	chr2_130159173_-	ncRNA_intronic
CAediting_212623	chr2_130159176_-	ncRNA_intronic
CAediting_212624	chr2_130159188_-	ncRNA_intronic
CAediting_212625	chr2_130159196_-	ncRNA_intronic
CAediting_212626	chr2_130159208_-	ncRNA_intronic
CAediting_212627	chr2_130159211_-	ncRNA_intronic
CAediting_212628	chr2_130159213_-	ncRNA_intronic
CAediting_212629	chr2_130159219_-	ncRNA_intronic
CAediting_212630	chr2_130159227_-	ncRNA_intronic
CAediting_212631	chr2_130159241_-	ncRNA_intronic
CAediting_212632	chr2_130159259_-	ncRNA_intronic
CAediting_212633	chr2_130159262_-	ncRNA_intronic
CAediting_212634	chr2_130159267_-	ncRNA_intronic
CAediting_212635	chr2_130159268_-	ncRNA_intronic
CAediting_212636	chr2_130159290_-	ncRNA_intronic
CAediting_212637	chr2_130159294_-	ncRNA_intronic
CAediting_212638	chr2_130159382_-	ncRNA_intronic
CAediting_212639	chr2_130159394_-	ncRNA_intronic
CAediting_212640	chr2_130159395_-	ncRNA_intronic
CAediting_212641	chr2_130159421_-	ncRNA_intronic
CAediting_212642	chr2_130159422_-	ncRNA_intronic
CAediting_212643	chr2_130159434_-	ncRNA_intronic
CAediting_212644	chr2_130159435_-	ncRNA_intronic
CAediting_212645	chr2_130159436_-	ncRNA_intronic
CAediting_212646	chr2_130159447_-	ncRNA_intronic
CAediting_212647	chr2_130159456_-	ncRNA_intronic
CAediting_212648	chr2_130159459_-	ncRNA_intronic
CAediting_212649	chr2_130159471_-	ncRNA_intronic
CAediting_212650	chr2_130159473_-	ncRNA_intronic
CAediting_212651	chr2_130159482_-	ncRNA_intronic
CAediting_212652	chr2_130159490_-	ncRNA_intronic
CAediting_212653	chr2_130159491_-	ncRNA_intronic
CAediting_212654	chr2_130159503_-	ncRNA_intronic
CAediting_212655	chr2_130159510_-	ncRNA_intronic
CAediting_212656	chr2_130159514_-	ncRNA_intronic
CAediting_212657	chr2_130159516_-	ncRNA_intronic
CAediting_212658	chr2_130159526_-	ncRNA_intronic
CAediting_212659	chr2_130159529_-	ncRNA_intronic
CAediting_212660	chr2_130159538_-	ncRNA_intronic
CAediting_212661	chr2_130159555_-	ncRNA_intronic
CAediting_212662	chr2_130159556_-	ncRNA_intronic
CAediting_212663	chr2_130159562_-	ncRNA_intronic
CAediting_212664	chr2_130159569_-	ncRNA_intronic
CAediting_212665	chr2_130159581_-	ncRNA_intronic
CAediting_212666	chr2_130159596_-	ncRNA_intronic
CAediting_212667	chr2_130159605_-	ncRNA_intronic
CAediting_212668	chr2_130159624_-	ncRNA_intronic
CAediting_212669	chr2_130159636_-	splicing
CAediting_212670	chr2_130165849_-	ncRNA_intronic
CAediting_212671	chr2_130166143_-	ncRNA_intronic
CAediting_212672	chr2_130166152_-	ncRNA_intronic
CAediting_212673	chr2_130167153_-	ncRNA_intronic
CAediting_212674	chr2_130167186_-	ncRNA_intronic
CAediting_212675	chr2_130167193_-	ncRNA_intronic
CAediting_212676	chr2_130167194_-	ncRNA_intronic
CAediting_212677	chr2_130167197_-	ncRNA_intronic
CAediting_212678	chr2_130167213_-	ncRNA_intronic
CAediting_212679	chr2_130167217_-	ncRNA_intronic
CAediting_212680	chr2_130167249_-	ncRNA_intronic
CAediting_212681	chr2_130167253_-	ncRNA_intronic
CAediting_212682	chr2_130167258_-	ncRNA_intronic
CAediting_212683	chr2_130167269_-	ncRNA_intronic
CAediting_212684	chr2_130167285_-	ncRNA_intronic
CAediting_212685	chr2_130167289_-	ncRNA_intronic
CAediting_212686	chr2_130167290_-	ncRNA_intronic
CAediting_212687	chr2_130167291_-	ncRNA_intronic
CAediting_212688	chr2_130167294_-	ncRNA_intronic
CAediting_212689	chr2_130167363_-	ncRNA_intronic
CAediting_212690	chr2_130167395_-	ncRNA_intronic
CAediting_212691	chr2_130167983_-	ncRNA_intronic
CAediting_212692	chr2_130167984_-	ncRNA_intronic
CAediting_212693	chr2_130167998_-	ncRNA_intronic
CAediting_212694	chr2_130168084_-	ncRNA_intronic
CAediting_212695	chr2_130168090_-	ncRNA_intronic
CAediting_212696	chr2_130168094_-	ncRNA_intronic
CAediting_212697	chr2_130168098_-	ncRNA_intronic
CAediting_212698	chr2_130168302_-	ncRNA_intronic
CAediting_212699	chr2_130168324_-	ncRNA_intronic
CAediting_212700	chr2_130168365_-	ncRNA_intronic
CAediting_212701	chr2_130168367_-	ncRNA_intronic
CAediting_212702	chr2_130168380_-	ncRNA_intronic
CAediting_212703	chr2_130168562_-	ncRNA_intronic
CAediting_212704	chr2_130168592_-	ncRNA_intronic
CAediting_212705	chr2_130168671_-	ncRNA_intronic
CAediting_212706	chr2_130168695_-	ncRNA_intronic
CAediting_212707	chr2_130168784_-	ncRNA_intronic
CAediting_212708	chr2_130168845_-	ncRNA_intronic
CAediting_212709	chr2_130168854_-	ncRNA_intronic
CAediting_212710	chr2_130168859_-	ncRNA_intronic
CAediting_212711	chr2_130168860_-	ncRNA_intronic
CAediting_212712	chr2_130168882_-	ncRNA_intronic
CAediting_212713	chr2_130168896_-	ncRNA_intronic
CAediting_212714	chr2_130169603_-	ncRNA_intronic
CAediting_212715	chr2_130169680_-	ncRNA_intronic
CAediting_212716	chr2_130169696_-	ncRNA_intronic
CAediting_212717	chr2_130170656_-	ncRNA_intronic
CAediting_212718	chr2_130170681_-	ncRNA_intronic
CAediting_212719	chr2_130170961_-	ncRNA_intronic
CAediting_212720	chr2_130171201_-	ncRNA_intronic
CAediting_212721	chr2_130171229_-	ncRNA_intronic
CAediting_212722	chr2_130171233_-	ncRNA_intronic
CAediting_212723	chr2_130171269_-	ncRNA_intronic
CAediting_212724	chr2_130171278_-	ncRNA_intronic
CAediting_212725	chr2_130171280_-	ncRNA_intronic
CAediting_212726	chr2_130171281_-	ncRNA_intronic
CAediting_212727	chr2_130171282_-	ncRNA_intronic
CAediting_212728	chr2_130171283_-	ncRNA_intronic
CAediting_212729	chr2_130171284_-	ncRNA_intronic
CAediting_212730	chr2_130171287_-	ncRNA_intronic
CAediting_212731	chr2_130171311_-	ncRNA_intronic
CAediting_212732	chr2_130171326_-	ncRNA_intronic
CAediting_212733	chr2_130177245_-	ncRNA_intronic
CAediting_212734	chr2_130177298_-	ncRNA_intronic
CAediting_212735	chr2_130177301_-	ncRNA_intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_212526	chr2_130157875_-	SINE	Alu	AluJr
CAediting_212527	chr2_130157884_-	SINE	Alu	AluJr
CAediting_212528	chr2_130157896_-	SINE	Alu	AluJr
CAediting_212529	chr2_130157897_-	SINE	Alu	AluJr
CAediting_212530	chr2_130157898_-	SINE	Alu	AluJr
CAediting_212531	chr2_130157940_-	SINE	Alu	AluJr
CAediting_212532	chr2_130157941_-	SINE	Alu	AluJr
CAediting_212533	chr2_130157966_-	SINE	Alu	AluJr
CAediting_212534	chr2_130157970_-	SINE	Alu	AluJr
CAediting_212535	chr2_130157972_-	SINE	Alu	AluJr
CAediting_212536	chr2_130157991_-	SINE	Alu	AluJr
CAediting_212537	chr2_130157992_-	SINE	Alu	AluJr
CAediting_212538	chr2_130157996_-	SINE	Alu	AluJr
CAediting_212539	chr2_130158000_-	SINE	Alu	AluJr
CAediting_212540	chr2_130158002_-	SINE	Alu	AluJr
CAediting_212541	chr2_130158005_-	SINE	Alu	AluJr
CAediting_212542	chr2_130158008_-	SINE	Alu	AluJr
CAediting_212543	chr2_130158016_-	SINE	Alu	AluJr
CAediting_212544	chr2_130158024_-	SINE	Alu	AluJr
CAediting_212545	chr2_130158031_-	SINE	Alu	AluJr
CAediting_212546	chr2_130158053_-	SINE	Alu	AluJr
CAediting_212547	chr2_130158057_-	SINE	Alu	AluJr
CAediting_212548	chr2_130158058_-	SINE	Alu	AluJr
CAediting_212549	chr2_130158071_-	SINE	Alu	AluJr
CAediting_212550	chr2_130158072_-	SINE	Alu	AluJr
CAediting_212551	chr2_130158078_-	SINE	Alu	AluJr
CAediting_212552	chr2_130158083_-	SINE	Alu	AluJr
CAediting_212553	chr2_130158096_-	SINE	Alu	AluJr
CAediting_212554	chr2_130158114_-	SINE	Alu	AluJr
CAediting_212555	chr2_130158118_-	SINE	Alu	AluJr
CAediting_212556	chr2_130158124_-	SINE	Alu	AluJr
CAediting_212557	chr2_130158131_-	SINE	Alu	AluJr
CAediting_212558	chr2_130158134_-	SINE	Alu	AluJr
CAediting_212559	chr2_130158135_-	SINE	Alu	AluJr
CAediting_212560	chr2_130158335_-	SINE	Alu	AluSx
CAediting_212561	chr2_130158385_-	SINE	Alu	AluSx
CAediting_212562	chr2_130158390_-	SINE	Alu	AluSx
CAediting_212563	chr2_130158394_-	SINE	Alu	AluSx
CAediting_212564	chr2_130158407_-	SINE	Alu	AluSx
CAediting_212565	chr2_130158413_-	SINE	Alu	AluSx
CAediting_212566	chr2_130158414_-	SINE	Alu	AluSx
CAediting_212567	chr2_130158422_-	SINE	Alu	AluSx
CAediting_212568	chr2_130158428_-	SINE	Alu	AluSx
CAediting_212569	chr2_130158432_-	SINE	Alu	AluSx
CAediting_212570	chr2_130158438_-	SINE	Alu	AluSx
CAediting_212571	chr2_130158441_-	SINE	Alu	AluSx
CAediting_212572	chr2_130158445_-	SINE	Alu	AluSx
CAediting_212573	chr2_130158449_-	SINE	Alu	AluSx
CAediting_212574	chr2_130158461_-	SINE	Alu	AluSx
CAediting_212575	chr2_130158465_-	SINE	Alu	AluSx
CAediting_212576	chr2_130158481_-	SINE	Alu	AluSx
CAediting_212577	chr2_130158484_-	SINE	Alu	AluSx
CAediting_212578	chr2_130158485_-	SINE	Alu	AluSx
CAediting_212579	chr2_130158486_-	SINE	Alu	AluSx
CAediting_212580	chr2_130158487_-	SINE	Alu	AluSx
CAediting_212581	chr2_130158488_-	SINE	Alu	AluSx
CAediting_212582	chr2_130158490_-	SINE	Alu	AluSx
CAediting_212583	chr2_130158491_-	SINE	Alu	AluSx
CAediting_212584	chr2_130158492_-	SINE	Alu	AluSx
CAediting_212585	chr2_130158503_-	SINE	Alu	AluSx
CAediting_212586	chr2_130158508_-	SINE	Alu	AluSx
CAediting_212587	chr2_130158516_-	SINE	Alu	AluSx
CAediting_212588	chr2_130158524_-	SINE	Alu	AluSx
CAediting_212589	chr2_130158552_-	SINE	Alu	AluSx
CAediting_212590	chr2_130158560_-	SINE	Alu	AluSx
CAediting_212591	chr2_130158568_-	SINE	Alu	AluSx
CAediting_212592	chr2_130159007_-	SINE	Alu	AluJb
CAediting_212593	chr2_130159008_-	SINE	Alu	AluJb
CAediting_212594	chr2_130159010_-	SINE	Alu	AluJb
CAediting_212595	chr2_130159011_-	SINE	Alu	AluJb
CAediting_212596	chr2_130159012_-	SINE	Alu	AluJb
CAediting_212597	chr2_130159027_-	SINE	Alu	AluJb
CAediting_212598	chr2_130159029_-	SINE	Alu	AluJb
CAediting_212599	chr2_130159033_-	SINE	Alu	AluJb
CAediting_212600	chr2_130159035_-	SINE	Alu	AluJb
CAediting_212601	chr2_130159049_-	SINE	Alu	AluJb
CAediting_212602	chr2_130159054_-	SINE	Alu	AluJb
CAediting_212603	chr2_130159062_-	SINE	Alu	AluJb
CAediting_212604	chr2_130159067_-	SINE	Alu	AluJb
CAediting_212605	chr2_130159071_-	SINE	Alu	AluJb
CAediting_212606	chr2_130159078_-	SINE	Alu	AluJb
CAediting_212607	chr2_130159080_-	SINE	Alu	AluJb
CAediting_212608	chr2_130159084_-	SINE	Alu	AluJb
CAediting_212609	chr2_130159092_-	SINE	Alu	AluJb
CAediting_212610	chr2_130159093_-	SINE	Alu	AluJb
CAediting_212611	chr2_130159108_-	SINE	Alu	AluJb
CAediting_212612	chr2_130159110_-	SINE	Alu	AluJb
CAediting_212613	chr2_130159123_-	SINE	Alu	AluJb
CAediting_212614	chr2_130159127_-	SINE	Alu	AluJb
CAediting_212615	chr2_130159161_-	SINE	Alu	AluJb
CAediting_212616	chr2_130159164_-	SINE	Alu	AluJb
CAediting_212617	chr2_130159165_-	SINE	Alu	AluJb
CAediting_212618	chr2_130159166_-	SINE	Alu	AluJb
CAediting_212619	chr2_130159167_-	SINE	Alu	AluJb
CAediting_212620	chr2_130159170_-	SINE	Alu	AluJb
CAediting_212621	chr2_130159172_-	SINE	Alu	AluJb
CAediting_212622	chr2_130159173_-	SINE	Alu	AluJb
CAediting_212623	chr2_130159176_-	SINE	Alu	AluJb
CAediting_212624	chr2_130159188_-	SINE	Alu	AluJb
CAediting_212625	chr2_130159196_-	SINE	Alu	AluJb
CAediting_212626	chr2_130159208_-	SINE	Alu	AluJb
CAediting_212627	chr2_130159211_-	SINE	Alu	AluJb
CAediting_212628	chr2_130159213_-	SINE	Alu	AluJb
CAediting_212629	chr2_130159219_-	SINE	Alu	AluJb
CAediting_212630	chr2_130159227_-	SINE	Alu	AluJb
CAediting_212631	chr2_130159241_-	SINE	Alu	AluJb
CAediting_212632	chr2_130159259_-	SINE	Alu	AluJb
CAediting_212633	chr2_130159262_-	SINE	Alu	AluJb
CAediting_212634	chr2_130159267_-	SINE	Alu	AluJb
CAediting_212635	chr2_130159268_-	SINE	Alu	AluJb
CAediting_212636	chr2_130159290_-	SINE	Alu	AluJb
CAediting_212638	chr2_130159382_-	SINE	Alu	AluSz
CAediting_212639	chr2_130159394_-	SINE	Alu	AluSz
CAediting_212640	chr2_130159395_-	SINE	Alu	AluSz
CAediting_212641	chr2_130159421_-	SINE	Alu	AluSz
CAediting_212642	chr2_130159422_-	SINE	Alu	AluSz
CAediting_212643	chr2_130159434_-	SINE	Alu	AluSz
CAediting_212644	chr2_130159435_-	SINE	Alu	AluSz
CAediting_212645	chr2_130159436_-	SINE	Alu	AluSz
CAediting_212646	chr2_130159447_-	SINE	Alu	AluSz
CAediting_212647	chr2_130159456_-	SINE	Alu	AluSz
CAediting_212648	chr2_130159459_-	SINE	Alu	AluSz
CAediting_212649	chr2_130159471_-	SINE	Alu	AluSz
CAediting_212650	chr2_130159473_-	SINE	Alu	AluSz
CAediting_212651	chr2_130159482_-	SINE	Alu	AluSz
CAediting_212652	chr2_130159490_-	SINE	Alu	AluSz
CAediting_212653	chr2_130159491_-	SINE	Alu	AluSz
CAediting_212654	chr2_130159503_-	SINE	Alu	AluSz
CAediting_212655	chr2_130159510_-	SINE	Alu	AluSz
CAediting_212656	chr2_130159514_-	SINE	Alu	AluSz
CAediting_212657	chr2_130159516_-	SINE	Alu	AluSz
CAediting_212658	chr2_130159526_-	SINE	Alu	AluSz
CAediting_212659	chr2_130159529_-	SINE	Alu	AluSz
CAediting_212660	chr2_130159538_-	SINE	Alu	AluSz
CAediting_212661	chr2_130159555_-	SINE	Alu	AluSz
CAediting_212662	chr2_130159556_-	SINE	Alu	AluSz
CAediting_212663	chr2_130159562_-	SINE	Alu	AluSz
CAediting_212664	chr2_130159569_-	SINE	Alu	AluSz
CAediting_212665	chr2_130159581_-	SINE	Alu	AluSz
CAediting_212666	chr2_130159596_-	SINE	Alu	AluSz
CAediting_212667	chr2_130159605_-	SINE	Alu	AluSz
CAediting_212668	chr2_130159624_-	SINE	Alu	AluSz
CAediting_212669	chr2_130159636_-	SINE	Alu	AluSz
CAediting_212670	chr2_130165849_-	SINE	Alu	AluJr4
CAediting_212671	chr2_130166143_-	SINE	Alu	AluSx1
CAediting_212672	chr2_130166152_-	SINE	Alu	AluSx1
CAediting_212673	chr2_130167153_-	SINE	Alu	AluSx1
CAediting_212674	chr2_130167186_-	SINE	Alu	AluSx1
CAediting_212675	chr2_130167193_-	SINE	Alu	AluSx1
CAediting_212676	chr2_130167194_-	SINE	Alu	AluSx1
CAediting_212677	chr2_130167197_-	SINE	Alu	AluSx1
CAediting_212678	chr2_130167213_-	SINE	Alu	AluSx1
CAediting_212679	chr2_130167217_-	SINE	Alu	AluSx1
CAediting_212680	chr2_130167249_-	SINE	Alu	AluSx1
CAediting_212681	chr2_130167253_-	SINE	Alu	AluSx1
CAediting_212682	chr2_130167258_-	SINE	Alu	AluSx1
CAediting_212683	chr2_130167269_-	SINE	Alu	AluSx1
CAediting_212684	chr2_130167285_-	SINE	Alu	AluSx1
CAediting_212685	chr2_130167289_-	SINE	Alu	AluSx1
CAediting_212686	chr2_130167290_-	SINE	Alu	AluSx1
CAediting_212687	chr2_130167291_-	SINE	Alu	AluSx1
CAediting_212688	chr2_130167294_-	SINE	Alu	AluSx1
CAediting_212689	chr2_130167363_-	SINE	Alu	AluSx1
CAediting_212690	chr2_130167395_-	SINE	Alu	AluSx1
CAediting_212691	chr2_130167983_-	SINE	Alu	AluJr
CAediting_212692	chr2_130167984_-	SINE	Alu	AluJr
CAediting_212693	chr2_130167998_-	SINE	Alu	AluJr
CAediting_212694	chr2_130168084_-	SINE	Alu	AluJr
CAediting_212695	chr2_130168090_-	SINE	Alu	AluJr
CAediting_212696	chr2_130168094_-	SINE	Alu	AluJr
CAediting_212697	chr2_130168098_-	SINE	Alu	AluJr
CAediting_212698	chr2_130168302_-	SINE	Alu	AluJb
CAediting_212699	chr2_130168324_-	SINE	Alu	AluJb
CAediting_212700	chr2_130168365_-	SINE	Alu	AluJb
CAediting_212701	chr2_130168367_-	SINE	Alu	AluJb
CAediting_212702	chr2_130168380_-	SINE	Alu	AluJb
CAediting_212703	chr2_130168562_-	SINE	Alu	AluJo
CAediting_212704	chr2_130168592_-	SINE	Alu	AluJo
CAediting_212705	chr2_130168671_-	SINE	Alu	AluJo
CAediting_212706	chr2_130168695_-	SINE	Alu	AluJo
CAediting_212707	chr2_130168784_-	SINE	Alu	AluSz6
CAediting_212708	chr2_130168845_-	SINE	Alu	AluSz6
CAediting_212709	chr2_130168854_-	SINE	Alu	AluSz6
CAediting_212710	chr2_130168859_-	SINE	Alu	AluSz6
CAediting_212711	chr2_130168860_-	SINE	Alu	AluSz6
CAediting_212712	chr2_130168882_-	SINE	Alu	AluSz6
CAediting_212713	chr2_130168896_-	SINE	Alu	AluSz6
CAediting_212714	chr2_130169603_-	SINE	Alu	AluJr
CAediting_212715	chr2_130169680_-	SINE	Alu	AluJr
CAediting_212716	chr2_130169696_-	SINE	Alu	AluJr
CAediting_212717	chr2_130170656_-	SINE	Alu	AluJr
CAediting_212718	chr2_130170681_-	SINE	Alu	AluJr
CAediting_212719	chr2_130170961_-	SINE	Alu	AluSx
CAediting_212720	chr2_130171201_-	SINE	Alu	AluSx
CAediting_212721	chr2_130171229_-	SINE	Alu	AluSx
CAediting_212722	chr2_130171233_-	SINE	Alu	AluSx
CAediting_212723	chr2_130171269_-	SINE	Alu	AluSx
CAediting_212724	chr2_130171278_-	SINE	Alu	AluSx
CAediting_212725	chr2_130171280_-	SINE	Alu	AluSx
CAediting_212726	chr2_130171281_-	SINE	Alu	AluSx
CAediting_212727	chr2_130171282_-	SINE	Alu	AluSx
CAediting_212728	chr2_130171283_-	SINE	Alu	AluSx
CAediting_212729	chr2_130171284_-	SINE	Alu	AluSx
CAediting_212730	chr2_130171287_-	SINE	Alu	AluSx
CAediting_212731	chr2_130171311_-	SINE	Alu	AluSx
CAediting_212732	chr2_130171326_-	SINE	Alu	AluSx
CAediting_212733	chr2_130177245_-	SINE	Alu	AluJo
CAediting_212734	chr2_130177298_-	SINE	Alu	AluJo
CAediting_212735	chr2_130177301_-	SINE	Alu	AluJo

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RNA A-to-I editing events in the alternative splicing sites for SMPD4

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
ES	CAediting_212542	chr2_130158008_-	130158008:130158016	5SS	0+6i	AGGTGTGCA	-27.62	AGGTGTGCG	-26.98
IR	CAediting_212542	chr2_130158008_-	130158008:130158016	5SS	0+6i	AGGTGTGCA	-27.62	AGGTGTGCG	-26.98
MEX_1	CAediting_212542	chr2_130158008_-	130158008:130158016	5SS	0+6i	AGGTGTGCA	-27.62	AGGTGTGCG	-26.98
ES	CAediting_212543	chr2_130158016_-	130158008:130158016	5SS	3+0i	AGGTGTGCA	-27.62	GGGTGTGCA	-31.5
IR	CAediting_212543	chr2_130158016_-	130158008:130158016	5SS	3+0i	AGGTGTGCA	-27.62	GGGTGTGCA	-31.5
MEX_1	CAediting_212543	chr2_130158016_-	130158008:130158016	5SS	3+0i	AGGTGTGCA	-27.62	GGGTGTGCA	-31.5
ES	CAediting_212655	chr2_130159510_-	130159506:130159514	5SS	0+2i	AGGCATGTG	-24.57	AGGCGTGTG	-24.03
MEX_2	CAediting_212655	chr2_130159510_-	130159506:130159514	5SS	0+2i	AGGCATGTG	-24.57	AGGCGTGTG	-24.03
ES	CAediting_212656	chr2_130159514_-	130159506:130159514	5SS	3+0i	AGGCATGTG	-24.57	GGGCATGTG	-27.89
MEX_2	CAediting_212656	chr2_130159514_-	130159506:130159514	5SS	3+0i	AGGCATGTG	-24.57	GGGCATGTG	-27.89
ES	CAediting_212669	chr2_130159636_-	130159632:130159654	3SS	0+2i	TTTTTTTTTTTTTTTTTGAGATG	4.74	TTTTTTTTTTTTTTTTTGGGATG	-3.21
IR	CAediting_212669	chr2_130159636_-	130159632:130159654	3SS	0+2i	TTTTTTTTTTTTTTTTTGAGATG	4.74	TTTTTTTTTTTTTTTTTGGGATG	-3.21
MEX_2	CAediting_212669	chr2_130159636_-	130159632:130159654	3SS	0+2i	TTTTTTTTTTTTTTTTTGAGATG	4.74	TTTTTTTTTTTTTTTTTGGGATG	-3.21

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000136699.18.SMPD4.

Correlation between RNA A-to-I editing and PSI for ENSG00000136699.18.SMPD4.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for SMPD4

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BLCA.CAediting_212607.ENSG00000136699.SMPD4.png
Soverview

BRCA.CAediting_212576.ENSG00000136699.SMPD4.png
Soverview

KIRC.CAediting_212669.ENSG00000136699.SMPD4.png
Soverview

LUSC.CAediting_212664.ENSG00000136699.SMPD4.png
Soverview

PRAD.CAediting_212613.ENSG00000136699.SMPD4.png
Soverview

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Protein coding region RNA A-to-I editings for SMPD4

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for SMPD4

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-508-5p	130152062	130152068	7mer-m8	130152061	130152083	152.00	-16.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-508-5p	130152062	130152068	7mer-m8	130152061	130152083	152.00	-16.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-508-5p	130152062	130152068	7mer-m8	130152061	130152083	152.00	-16.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-508-5p	130152062	130152068	7mer-m8	130152061	130152083	152.00	-16.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-508-5p	130152062	130152068	7mer-m8	130152061	130152083	152.00	-16.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-508-5p	130152062	130152068	7mer-m8	130152061	130152083	152.00	-16.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-508-5p	130152062	130152068	7mer-m8	130152061	130152083	152.00	-16.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-9902	130152064	130152071	8mer-1a	130152064	130152086	149.00	-14.04
CAediting_212658	chr2_130159526_-	ENSG00000136699.18	ENST00000433118	hsa-miR-4691-3p	130159522	130159528	7mer-m8	130159521	130159542	146.00	-25.49
CAediting_212663	chr2_130159562_-	ENSG00000136699.18	ENST00000433118	hsa-miR-4497	130159560	130159566	7mer-m8	130159559	130159573	147.00	-21.69
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-25-5p	130159567	130159573	7mer-m8	130159566	130159585	151.00	-21.80
CAediting_212662	chr2_130159556_-	ENSG00000136699.18	ENST00000433118	hsa-miR-3145-5p	130159553	130159559	7mer-m8	130159552	130159573	142.00	-9.01
CAediting_212666	chr2_130159596_-	ENSG00000136699.18	ENST00000433118	hsa-miR-192-3p	130159594	130159600	7mer-m8	130159593	130159613	143.00	-13.07
CAediting_212666	chr2_130159596_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6872-3p	130159591	130159597	7mer-m8	130159590	130159610	140.00	-17.09
CAediting_212667	chr2_130159605_-	ENSG00000136699.18	ENST00000433118	hsa-miR-324-5p	130159600	130159607	8mer-1a	130159600	130159623	163.00	-26.85
CAediting_212667	chr2_130159605_-	ENSG00000136699.18	ENST00000433118	hsa-miR-7977	130159604	130159610	7mer-m8	130159603	130159620	151.00	-18.12

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-5684	130152062	130152068	7mer-m8	130152061	130152080	140	-12.77
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-618	130152061	130152067	7mer-m8	130152060	130152085	144	-10.27
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000431183	hsa-miR-6508-5p	130152064	130152071	8mer-1a	130152064	130152084	141	-12.32
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-5684	130152062	130152068	7mer-m8	130152061	130152080	140	-12.77
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-618	130152061	130152067	7mer-m8	130152060	130152085	144	-10.27
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000454468	hsa-miR-6508-5p	130152064	130152071	8mer-1a	130152064	130152084	141	-12.32
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-5684	130152062	130152068	7mer-m8	130152061	130152080	140	-12.77
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-618	130152061	130152067	7mer-m8	130152060	130152085	144	-10.27
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000412570	hsa-miR-6508-5p	130152064	130152071	8mer-1a	130152064	130152084	141	-12.32
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-12114	130159566	130159572	7mer-m8	130159565	130159587	155	-24.2
CAediting_212663	chr2_130159562_-	ENSG00000136699.18	ENST00000433118	hsa-miR-1298-3p	130159559	130159565	7mer-m8	130159558	130159578	140	-12.25
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-3689d	130159564	130159570	7mer-m8	130159563	130159585	147	-19.41
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-3689d	130159564	130159570	7mer-m8	130159563	130159585	147	-19.41
CAediting_212663	chr2_130159562_-	ENSG00000136699.18	ENST00000433118	hsa-miR-4314	130159560	130159566	7mer-m8	130159559	130159576	150	-16.97
CAediting_212660	chr2_130159538_-	ENSG00000136699.18	ENST00000433118	hsa-miR-4478	130159534	130159540	7mer-m8	130159533	130159550	154	-25.02
CAediting_212660	chr2_130159538_-	ENSG00000136699.18	ENST00000433118	hsa-miR-4649-3p	130159537	130159543	7mer-m8	130159536	130159556	140	-12.17
CAediting_212658	chr2_130159526_-	ENSG00000136699.18	ENST00000433118	hsa-miR-5690	130159522	130159528	7mer-m8	130159521	130159541	145	-16.75
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6134	130159565	130159571	7mer-m8	130159564	130159581	155	-23.47
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-620	130159569	130159575	7mer-m8	130159568	130159586	143	-10.32
CAediting_212667	chr2_130159605_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6512-3p	130159604	130159611	8mer-1a	130159604	130159625	150	-23.56
CAediting_212667	chr2_130159605_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6720-5p	130159604	130159611	8mer-1a	130159604	130159625	152	-24.07
CAediting_212663	chr2_130159562_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6779-5p	130159562	130159568	7mer-m8	130159561	130159579	152	-23.9
CAediting_212663	chr2_130159562_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6780a-5p	130159562	130159568	7mer-m8	130159561	130159585	155	-26.05
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6851-5p	130159564	130159570	7mer-m8	130159563	130159589	150	-27.71
CAediting_212664	chr2_130159569_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6880-5p	130159567	130159573	7mer-m8	130159566	130159587	152	-21.82
CAediting_212660	chr2_130159538_-	ENSG00000136699.18	ENST00000433118	hsa-miR-7160-5p	130159536	130159542	7mer-m8	130159535	130159555	142	-14.76
CAediting_212660	chr2_130159538_-	ENSG00000136699.18	ENST00000433118	hsa-miR-7162-3p	130159537	130159542	6mer	130159536	130159555	144	-16.54
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-5684	130152062	130152068	7mer-m8	130152061	130152080	140	-12.77
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-618	130152061	130152067	7mer-m8	130152060	130152085	144	-10.27
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000433118	hsa-miR-6508-5p	130152064	130152071	8mer-1a	130152064	130152084	141	-12.32
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-5684	130152062	130152068	7mer-m8	130152061	130152080	140	-12.77
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-618	130152061	130152067	7mer-m8	130152060	130152085	144	-10.27
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000351288	hsa-miR-6508-5p	130152064	130152071	8mer-1a	130152064	130152084	141	-12.32
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-5684	130152062	130152068	7mer-m8	130152061	130152080	140	-12.77
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-618	130152061	130152067	7mer-m8	130152060	130152085	144	-10.27
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000439886	hsa-miR-6508-5p	130152064	130152071	8mer-1a	130152064	130152084	141	-12.32
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-517-5p	130152063	130152069	7mer-m8	130152062	130152083	140	-10.04
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-5684	130152062	130152068	7mer-m8	130152061	130152080	140	-12.77
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-618	130152061	130152067	7mer-m8	130152060	130152085	144	-10.27
CAediting_212525	chr2_130152066_-	ENSG00000136699.18	ENST00000409031	hsa-miR-6508-5p	130152064	130152071	8mer-1a	130152064	130152084	141	-12.32

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_393	chr1_1167164_+	ENSG00000136699.18	ENST00000454468	hsa-miR-200b-3p	130156623	130156629	7mer-m8	130156622	130156643	146	-15.59
CAediting_393	chr1_1167164_+	ENSG00000136699.18	ENST00000412570	hsa-miR-200b-3p	130156623	130156629	7mer-m8	130156622	130156643	146	-15.59
CAediting_393	chr1_1167164_+	ENSG00000136699.18	ENST00000433118	hsa-miR-200b-3p	130156623	130156629	7mer-m8	130156622	130156643	146	-15.59
CAediting_1368054	chr19_46709310_-	ENSG00000136699.18	ENST00000431183	hsa-miR-320e	130152264	130152270	7mer-m8	130152263	130152280	152	-20.22
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000431183	hsa-miR-589-3p	130151778	130151784	7mer-m8	130151777	130151800	153	-17.27
CAediting_228905	chr2_188297554_+	ENSG00000136699.18	ENST00000454468	hsa-miR-561-3p	130167465	130167471	7mer-m8	130167464	130167486	154	-19.24
CAediting_228905	chr2_188297554_+	ENSG00000136699.18	ENST00000454468	hsa-miR-561-3p	130156640	130156647	8mer-1a	130156640	130156661	148	-10.71
CAediting_604450	chr7_133034877_-	ENSG00000136699.18	ENST00000454468	hsa-miR-3654	130156649	130156656	8mer-1a	130156649	130156667	153	-20.92
CAediting_1368054	chr19_46709310_-	ENSG00000136699.18	ENST00000454468	hsa-miR-320e	130152264	130152270	7mer-m8	130152263	130152280	152	-20.22
CAediting_580943	chr7_100356700_+	ENSG00000136699.18	ENST00000454468	hsa-miR-6840-3p	130152850	130152857	8mer-1a	130152850	130152872	145	-23.37
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000454468	hsa-miR-589-3p	130151778	130151784	7mer-m8	130151777	130151800	153	-17.27
CAediting_228905	chr2_188297554_+	ENSG00000136699.18	ENST00000412570	hsa-miR-561-3p	130167465	130167471	7mer-m8	130167464	130167486	154	-19.24
CAediting_228905	chr2_188297554_+	ENSG00000136699.18	ENST00000412570	hsa-miR-561-3p	130156640	130156647	8mer-1a	130156640	130156661	148	-10.71
CAediting_604450	chr7_133034877_-	ENSG00000136699.18	ENST00000412570	hsa-miR-3654	130156649	130156656	8mer-1a	130156649	130156667	153	-20.92
CAediting_1368054	chr19_46709310_-	ENSG00000136699.18	ENST00000412570	hsa-miR-320e	130152264	130152270	7mer-m8	130152263	130152280	152	-20.22
CAediting_580943	chr7_100356700_+	ENSG00000136699.18	ENST00000412570	hsa-miR-6840-3p	130152850	130152857	8mer-1a	130152850	130152872	145	-23.37
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000412570	hsa-miR-589-3p	130151778	130151784	7mer-m8	130151777	130151800	153	-17.27
CAediting_228905	chr2_188297554_+	ENSG00000136699.18	ENST00000433118	hsa-miR-561-3p	130167465	130167471	7mer-m8	130167464	130167486	154	-19.24
CAediting_228905	chr2_188297554_+	ENSG00000136699.18	ENST00000433118	hsa-miR-561-3p	130156640	130156647	8mer-1a	130156640	130156661	148	-10.71
CAediting_604450	chr7_133034877_-	ENSG00000136699.18	ENST00000433118	hsa-miR-3654	130156649	130156656	8mer-1a	130156649	130156667	153	-20.92
CAediting_1368054	chr19_46709310_-	ENSG00000136699.18	ENST00000433118	hsa-miR-320e	130152264	130152270	7mer-m8	130152263	130152280	152	-20.22
CAediting_580943	chr7_100356700_+	ENSG00000136699.18	ENST00000433118	hsa-miR-6840-3p	130152850	130152857	8mer-1a	130152850	130152872	145	-23.37
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000433118	hsa-miR-589-3p	130151778	130151784	7mer-m8	130151777	130151800	153	-17.27
CAediting_1368054	chr19_46709310_-	ENSG00000136699.18	ENST00000351288	hsa-miR-320e	130152264	130152270	7mer-m8	130152263	130152280	152	-20.22
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000351288	hsa-miR-589-3p	130151778	130151784	7mer-m8	130151777	130151800	153	-17.27
CAediting_1368054	chr19_46709310_-	ENSG00000136699.18	ENST00000439886	hsa-miR-320e	130152264	130152270	7mer-m8	130152263	130152280	152	-20.22
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000439886	hsa-miR-589-3p	130151778	130151784	7mer-m8	130151777	130151800	153	-17.27
CAediting_1368054	chr19_46709310_-	ENSG00000136699.18	ENST00000409031	hsa-miR-320e	130152264	130152270	7mer-m8	130152263	130152280	152	-20.22
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000409031	hsa-miR-589-3p	130151778	130151784	7mer-m8	130151777	130151800	153	-17.27
CAediting_228905	chr2_188297554_+	ENSG00000136699.18	ENST00000439029	hsa-miR-561-3p	130167465	130167471	7mer-m8	130167464	130167486	154	-19.24
CAediting_468389	chr6_31355314_-	ENSG00000136699.18	ENST00000454468	hsa-miR-6891-5p	130172385	130172390	6mer	130172384	130172402	145	-28.65
CAediting_468389	chr6_31355314_-	ENSG00000136699.18	ENST00000412570	hsa-miR-6891-5p	130172385	130172390	6mer	130172384	130172402	145	-28.65

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID	Position	ENSG	ENST	miRNA	Targetscan start	Targetscan end	Targetscan score	Miranda start	Miranda end	Miranda score	Miranda energy
CAediting_77128	chr1_85133844_+	ENSG00000136699.18	ENST00000454468	hsa-miR-4423-3p	130172457	130172463	7mer-m8	130172456	130172476	140	-12.66
CAediting_1524209	chrX_134546392_-	ENSG00000136699.18	ENST00000454468	hsa-miR-503-5p	130152631	130152637	7mer-m8	130152630	130152652	144	-15.53
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000454468	hsa-miR-589-3p	130152658	130152664	7mer-m8	130152657	130152682	145	-14.15
CAediting_580943	chr7_100356700_+	ENSG00000136699.18	ENST00000454468	hsa-miR-6840-3p	130152715	130152721	7mer-m8	130152714	130152732	147	-31.2
CAediting_77128	chr1_85133844_+	ENSG00000136699.18	ENST00000412570	hsa-miR-4423-3p	130172457	130172463	7mer-m8	130172456	130172476	140	-12.66
CAediting_1524209	chrX_134546392_-	ENSG00000136699.18	ENST00000412570	hsa-miR-503-5p	130152631	130152637	7mer-m8	130152630	130152652	144	-15.53
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000412570	hsa-miR-589-3p	130152658	130152664	7mer-m8	130152657	130152682	145	-14.15
CAediting_580943	chr7_100356700_+	ENSG00000136699.18	ENST00000412570	hsa-miR-6840-3p	130152715	130152721	7mer-m8	130152714	130152732	147	-31.2
CAediting_1524209	chrX_134546392_-	ENSG00000136699.18	ENST00000433118	hsa-miR-503-5p	130152631	130152637	7mer-m8	130152630	130152652	144	-15.53
CAediting_524911	chr7_5495852_-	ENSG00000136699.18	ENST00000433118	hsa-miR-589-3p	130152658	130152664	7mer-m8	130152657	130152682	145	-14.15
CAediting_580943	chr7_100356700_+	ENSG00000136699.18	ENST00000433118	hsa-miR-6840-3p	130152715	130152721	7mer-m8	130152714	130152732	147	-31.2

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for SMPD4

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000351288.9	protein_coding
ENST00000409031.4	protein_coding
ENST00000412570.4	nonsense_mediated_decay
ENST00000431183.5	protein_coding
ENST00000433118.4	nonsense_mediated_decay
ENST00000439886.4	protein_coding
ENST00000454468.4	nonsense_mediated_decay
ENST00000482171.4	retained_intron
ENST00000491128.4	retained_intron

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_212525	ENST00000351288.9	chr2_130152066_-	-1409.80	-1403.20	-1409.80
CAediting_212525	ENST00000409031.4	chr2_130152066_-	-2025.40	-2018.80	-2025.40
CAediting_212525	ENST00000412570.4	chr2_130152066_-	-1384.60	-1378.00	-1384.60
CAediting_212525	ENST00000431183.5	chr2_130152066_-	-1402.50	-1395.90	-1402.50
CAediting_212525	ENST00000433118.4	chr2_130152066_-	-1290.10	-1283.50	-1310.70
CAediting_212656	ENST00000433118.4	chr2_130159514_-	-1282.80	-1283.50	-1310.70
CAediting_212657	ENST00000433118.4	chr2_130159516_-	-1284.70	-1283.50	-1310.70
CAediting_212658	ENST00000433118.4	chr2_130159526_-	-1283.30	-1283.50	-1310.70
CAediting_212659	ENST00000433118.4	chr2_130159529_-	-1286.40	-1283.50	-1310.70
CAediting_212660	ENST00000433118.4	chr2_130159538_-	-1284.30	-1283.50	-1310.70
CAediting_212661	ENST00000433118.4	chr2_130159555_-	-1287.50	-1283.50	-1310.70
CAediting_212662	ENST00000433118.4	chr2_130159556_-	-1285.50	-1283.50	-1310.70
CAediting_212663	ENST00000433118.4	chr2_130159562_-	-1283.50	-1283.50	-1310.70
CAediting_212664	ENST00000433118.4	chr2_130159569_-	-1283.50	-1283.50	-1310.70
CAediting_212665	ENST00000433118.4	chr2_130159581_-	-1283.50	-1283.50	-1310.70
CAediting_212666	ENST00000433118.4	chr2_130159596_-	-1287.10	-1283.50	-1310.70
CAediting_212667	ENST00000433118.4	chr2_130159605_-	-1285.80	-1283.50	-1310.70
CAediting_212668	ENST00000433118.4	chr2_130159624_-	-1283.80	-1283.50	-1310.70
CAediting_212525	ENST00000439886.4	chr2_130152066_-	-1307.10	-1300.50	-1307.10
CAediting_212525	ENST00000454468.4	chr2_130152066_-	-1363.00	-1357.60	-1363.00
CAediting_212525	ENST00000482171.4	chr2_130152066_-	-1833.90	-1827.30	-1839.80
CAediting_212526	ENST00000482171.4	chr2_130157875_-	-1831.40	-1827.30	-1839.80
CAediting_212527	ENST00000482171.4	chr2_130157884_-	-1827.30	-1827.30	-1839.80
CAediting_212528	ENST00000482171.4	chr2_130157896_-	-1827.30	-1827.30	-1839.80
CAediting_212529	ENST00000482171.4	chr2_130157897_-	-1827.30	-1827.30	-1839.80
CAediting_212530	ENST00000482171.4	chr2_130157898_-	-1827.30	-1827.30	-1839.80
CAediting_212531	ENST00000482171.4	chr2_130157940_-	-1827.40	-1827.30	-1839.80
CAediting_212532	ENST00000482171.4	chr2_130157941_-	-1829.20	-1827.30	-1839.80
CAediting_212525	ENST00000491128.4	chr2_130152066_-	-1020.60	-1014.00	-1020.60

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Relation with ADAR for SMPD4

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
BRCA	CAediting_212525	chr2_130152066_-	0.00070622207914071	0.390068567667603	.	.	.	.
BRCA	CAediting_212553	chr2_130158096_-	0.000857605318824833	0.198826147459507	.	.	.	.
LUSC	CAediting_212553	chr2_130158096_-	0.023264489909725	0.272940401228312	.	.	.	.
BRCA	CAediting_212571	chr2_130158441_-	0.0143876333752191	0.210237030834642	.	.	.	.
BRCA	CAediting_212573	chr2_130158449_-	0.0029419620772317	0.183736103884228	.	.	.	.
LUSC	CAediting_212573	chr2_130158449_-	.	.	.	.	0.0487122140400886	0.25140997190121
STAD	CAediting_212577	chr2_130158484_-	0.00864149746118632	0.250384450637297	.	.	.	.
STAD	CAediting_212578	chr2_130158485_-	0.00897831538474944	0.251477176747071	.	.	.	.
OV	CAediting_212578	chr2_130158485_-	0.0387059313904222	0.210275472345746	.	.	.	.
BRCA	CAediting_212600	chr2_130159035_-	.	.	.	.	0.0193246872717487	0.131957637963888
OV	CAediting_212607	chr2_130159080_-	0.0390354021279977	0.16927764609288	.	.	.	.
PCPG	CAediting_212613	chr2_130159123_-	.	.	0.0355608223322323	0.263273541693122	.	.
PRAD	CAediting_212614	chr2_130159127_-	0.0239046391566802	0.291362563949229	.	.	.	.
TGCT	CAediting_212614	chr2_130159127_-	0.002684262668866	0.404209491775158	.	.	.	.
BRCA	CAediting_212617	chr2_130159165_-	.	.	0.0234394088834674	0.151728698724061	.	.
OV	CAediting_212648	chr2_130159459_-	0.0464913166415825	0.258081471438405	.	.	.	.
BRCA	CAediting_212660	chr2_130159538_-	.	.	0.0464674452903359	0.165073072959626	.	.
OV	CAediting_212660	chr2_130159538_-	.	.	.	.	0.0130143015585618	0.201689104650673
BRCA	CAediting_212664	chr2_130159569_-	0.0215779477636137	0.159259492154272	.	.	.	.

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Relation with cancer stages for SMPD4

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
BRCA	pathologic_stage	CAediting_212553	chr2_130158096_-	0.0149043143306665	0.147496081683083
BRCA	pathologic_stage	CAediting_212600	chr2_130159035_-	0.00476043382220558	0.160974604721657
BRCA	pathologic_stage	CAediting_212614	chr2_130159127_-	0.0214362813092471	0.133437046628564
ESCA	clinical_stage	CAediting_212544	chr2_130158024_-	0.00730931731978844	-0.386352431850336
ESCA	clinical_stage	CAediting_212553	chr2_130158096_-	0.017338944124067	-0.353131533181635
ESCA	clinical_stage	CAediting_212573	chr2_130158449_-	0.0234609576020841	-0.353293438561994
ESCA	clinical_stage	CAediting_212578	chr2_130158485_-	0.00362618106517969	-0.454819092810826
ESCA	clinical_stage	CAediting_212614	chr2_130159127_-	0.0141128188749069	-0.51530420518544
ESCA	clinical_stage	CAediting_212664	chr2_130159569_-	0.017445827318674	-0.453733473530354
KIRC	pathologic_stage	CAediting_212553	chr2_130158096_-	0.00478340892668804	0.381834185609518
KIRC	pathologic_stage	CAediting_212600	chr2_130159035_-	0.0371873103242136	0.239495755249279
LUAD	pathologic_stage	CAediting_212600	chr2_130159035_-	0.0487407692248161	0.193764149861234
LUSC	pathologic_stage	CAediting_212544	chr2_130158024_-	0.0077769106259091	0.288524408553296
STAD	pathologic_stage	CAediting_212607	chr2_130159080_-	0.00585260689716063	0.286769602139918
THCA	pathologic_stage	CAediting_212607	chr2_130159080_-	0.0404813471432573	0.191372913381614

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Relation with survival for SMPD4

Correlation between RNA editing and survival

Cancer	CAeditomID	position	KMpvalue	Coxpvalue	CoxHR
LUSC	CAediting_212664	chr2_130159569_-	0.0156270055175107	0.0286557	32.4174

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RelatedDrugs for SMPD4

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SMPD4

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene