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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: HAUS7 (CAeditome ID:55559)

Gene summary for HAUS7

check button Gene summary
Gene informationGene symbol

HAUS7

Gene ID

55559

Gene nameHAUS augmin like complex subunit 7
SynonymsUCHL5IP|UIP1
Cytomap

Xq28

Type of geneprotein-coding
DescriptionHAUS augmin-like complex subunit 726S proteasome-associated UCH37-interacting protein 1X-linked protein STS1769
Modification date20210518
UniProtAcc

Q99871

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
HAUS7

GO:0005813

HAUS augmin-like complex subunit 7

21399614

HAUS7

GO:1990498

HAUS augmin-like complex subunit 7

30723163

HAUS7

GO:0070652

HAUS augmin-like complex subunit 7

19369198

HAUS7

GO:0070652

HAUS augmin-like complex subunit 7

19427217


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RNA A-to-I events for HAUS7

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000213397.9

check button RNA A-to-I editing events in Cancer.
CAediting_1526680(153452852, -), CAediting_1526681(153453958, -), CAediting_1526682(153458097, -), CAediting_1526683(153458624, -), CAediting_1526684(153458674, -), CAediting_1526685(153458723, -), CAediting_1526686(153458731, -), CAediting_1526687(153458736, -), CAediting_1526688(153458897, -), CAediting_1526689(153458907, -), CAediting_1526690(153458966, -), CAediting_1526691(153458976, -), CAediting_1526692(153459004, -), CAediting_1526693(153459093, -), CAediting_1526694(153459107, -), CAediting_1526695(153459117, -), CAediting_1526696(153459118, -), CAediting_1526697(153459119, -), CAediting_1526698(153459122, -), CAediting_1526699(153459123, -), CAediting_1526700(153459124, -), CAediting_1526701(153459126, -), CAediting_1526702(153459132, -), CAediting_1526703(153459134, -), CAediting_1526704(153459144, -), CAediting_1526705(153459158, -), CAediting_1526706(153459159, -), CAediting_1526707(153459163, -), CAediting_1526708(153459172, -), CAediting_1526709(153459206, -), CAediting_1526710(153459225, -), CAediting_1526711(153459786, -), CAediting_1526712(153459795, -), CAediting_1526713(153459823, -), CAediting_1526714(153459904, -), CAediting_1526715(153459916, -), CAediting_1526716(153461644, -), CAediting_1526717(153461664, -), CAediting_1526718(153461713, -), CAediting_1526719(153461764, -), CAediting_1526720(153461770, -), CAediting_1526721(153461780, -), CAediting_1526722(153461825, -), CAediting_1526723(153461844, -), CAediting_1526724(153461861, -),

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RNA editing positional annotations for HAUS7 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1526680chrX_153452852_-ncRNA_intronic
CAediting_1526681chrX_153453958_-ncRNA_intronic
CAediting_1526682chrX_153458097_-ncRNA_intronic
CAediting_1526683chrX_153458624_-ncRNA_intronic
CAediting_1526684chrX_153458674_-ncRNA_intronic
CAediting_1526685chrX_153458723_-ncRNA_intronic
CAediting_1526686chrX_153458731_-ncRNA_intronic
CAediting_1526687chrX_153458736_-ncRNA_intronic
CAediting_1526688chrX_153458897_-ncRNA_intronic
CAediting_1526689chrX_153458907_-ncRNA_intronic
CAediting_1526690chrX_153458966_-ncRNA_intronic
CAediting_1526691chrX_153458976_-ncRNA_intronic
CAediting_1526692chrX_153459004_-ncRNA_intronic
CAediting_1526693chrX_153459093_-ncRNA_intronic
CAediting_1526694chrX_153459107_-ncRNA_intronic
CAediting_1526695chrX_153459117_-ncRNA_intronic
CAediting_1526696chrX_153459118_-ncRNA_intronic
CAediting_1526697chrX_153459119_-ncRNA_intronic
CAediting_1526698chrX_153459122_-ncRNA_intronic
CAediting_1526699chrX_153459123_-ncRNA_intronic
CAediting_1526700chrX_153459124_-ncRNA_intronic
CAediting_1526701chrX_153459126_-ncRNA_intronic
CAediting_1526702chrX_153459132_-ncRNA_intronic
CAediting_1526703chrX_153459134_-ncRNA_intronic
CAediting_1526704chrX_153459144_-ncRNA_intronic
CAediting_1526705chrX_153459158_-ncRNA_intronic
CAediting_1526706chrX_153459159_-ncRNA_intronic
CAediting_1526707chrX_153459163_-ncRNA_intronic
CAediting_1526708chrX_153459172_-ncRNA_intronic
CAediting_1526709chrX_153459206_-ncRNA_intronic
CAediting_1526710chrX_153459225_-ncRNA_intronic
CAediting_1526711chrX_153459786_-ncRNA_intronic
CAediting_1526712chrX_153459795_-ncRNA_intronic
CAediting_1526713chrX_153459823_-ncRNA_intronic
CAediting_1526714chrX_153459904_-ncRNA_intronic
CAediting_1526715chrX_153459916_-ncRNA_intronic
CAediting_1526716chrX_153461644_-ncRNA_intronic
CAediting_1526717chrX_153461664_-ncRNA_intronic
CAediting_1526718chrX_153461713_-ncRNA_intronic
CAediting_1526719chrX_153461764_-ncRNA_intronic
CAediting_1526720chrX_153461770_-ncRNA_intronic
CAediting_1526721chrX_153461780_-ncRNA_intronic
CAediting_1526722chrX_153461825_-ncRNA_intronic
CAediting_1526723chrX_153461844_-ncRNA_intronic
CAediting_1526724chrX_153461861_-ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1526680chrX_153452852_-SINEAluAluSx1
CAediting_1526681chrX_153453958_-SINEAluAluJb
CAediting_1526683chrX_153458624_-LINEL1L1M4
CAediting_1526684chrX_153458674_-LINEL1L1M4
CAediting_1526685chrX_153458723_-LINEL1L1M4
CAediting_1526686chrX_153458731_-LINEL1L1M4
CAediting_1526687chrX_153458736_-LINEL1L1M4
CAediting_1526688chrX_153458897_-SINEAluAluJo
CAediting_1526689chrX_153458907_-SINEAluAluJo
CAediting_1526690chrX_153458966_-SINEAluAluJo
CAediting_1526691chrX_153458976_-SINEAluAluJo
CAediting_1526692chrX_153459004_-SINEAluAluJo
CAediting_1526693chrX_153459093_-LINEL1L1M4
CAediting_1526694chrX_153459107_-LINEL1L1M4
CAediting_1526695chrX_153459117_-LINEL1L1M4
CAediting_1526696chrX_153459118_-LINEL1L1M4
CAediting_1526697chrX_153459119_-LINEL1L1M4
CAediting_1526698chrX_153459122_-LINEL1L1M4
CAediting_1526699chrX_153459123_-LINEL1L1M4
CAediting_1526700chrX_153459124_-LINEL1L1M4
CAediting_1526701chrX_153459126_-LINEL1L1M4
CAediting_1526702chrX_153459132_-LINEL1L1M4
CAediting_1526703chrX_153459134_-LINEL1L1M4
CAediting_1526704chrX_153459144_-LINEL1L1M4
CAediting_1526705chrX_153459158_-LINEL1L1M4
CAediting_1526706chrX_153459159_-LINEL1L1M4
CAediting_1526707chrX_153459163_-LINEL1L1M4
CAediting_1526708chrX_153459172_-LINEL1L1M4
CAediting_1526709chrX_153459206_-LINEL1L1M4
CAediting_1526710chrX_153459225_-LINEL1L1M4
CAediting_1526711chrX_153459786_-SINEAluAluJr
CAediting_1526712chrX_153459795_-SINEAluAluJr
CAediting_1526713chrX_153459823_-SINEAluAluJr
CAediting_1526714chrX_153459904_-SINEAluAluJr
CAediting_1526715chrX_153459916_-SINEAluAluJr
CAediting_1526716chrX_153461644_-LINEL1L1PREC2
CAediting_1526717chrX_153461664_-LINEL1L1PREC2
CAediting_1526718chrX_153461713_-LINEL1L1PREC2
CAediting_1526719chrX_153461764_-LINEL1L1PREC2
CAediting_1526720chrX_153461770_-LINEL1L1PREC2
CAediting_1526721chrX_153461780_-LINEL1L1PREC2
CAediting_1526722chrX_153461825_-LINEL1L1PREC2
CAediting_1526723chrX_153461844_-LINEL1L1PREC2
CAediting_1526724chrX_153461861_-LINEL1L1PREC2

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RNA A-to-I editing events in the alternative splicing sites for HAUS7

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000213397.9.HAUS7.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000213397.9.HAUS7.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for HAUS7

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for HAUS7

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for HAUS7

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1526716chrX_153461644_-ENSG00000213397.9ENST00000370210hsa-miR-7112-3p1534616431534616497mer-m8153461642153461664149.00-15.41
CAediting_1526718chrX_153461713_-ENSG00000213397.9ENST00000370210hsa-miR-44351534617091534617157mer-m8153461708153461728162.00-21.75
CAediting_1526718chrX_153461713_-ENSG00000213397.9ENST00000370210hsa-miR-44351534617091534617157mer-m8153461708153461728162.00-21.75
CAediting_1526719chrX_153461764_-ENSG00000213397.9ENST00000370210hsa-miR-12031534617631534617697mer-m8153461762153461787141.00-21.64
CAediting_1526720chrX_153461770_-ENSG00000213397.9ENST00000370210hsa-miR-1233-3p1534617661534617727mer-m8153461765153461784150.00-22.64
CAediting_1526720chrX_153461770_-ENSG00000213397.9ENST00000370210hsa-miR-1233-3p1534617661534617727mer-m8153461765153461784150.00-22.64
CAediting_1526720chrX_153461770_-ENSG00000213397.9ENST00000370210hsa-miR-42901534617681534617747mer-m8153461767153461785144.00-15.33
CAediting_1526720chrX_153461770_-ENSG00000213397.9ENST00000370210hsa-miR-4687-5p1534617671534617737mer-m8153461766153461786153.00-21.99

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1526716chrX_153461644_-ENSG00000213397.9ENST00000370210hsa-miR-3605-3p1534616391534616446mer153461638153461660151-22
CAediting_1526723chrX_153461844_-ENSG00000213397.9ENST00000370210hsa-miR-45031534618431534618497mer-m8153461842153461862143-8.29
CAediting_1526724chrX_153461861_-ENSG00000213397.9ENST00000370210hsa-miR-46791534618601534618656mer153461859153461882140-16.52
CAediting_1526724chrX_153461861_-ENSG00000213397.9ENST00000370210hsa-miR-46791534618601534618656mer153461859153461882140-16.52
CAediting_1526724chrX_153461861_-ENSG00000213397.9ENST00000370210hsa-miR-4725-5p1534618551534618628mer-1a153461855153461875147-17.57
CAediting_1526724chrX_153461861_-ENSG00000213397.9ENST00000370210hsa-miR-504-5p1534618551534618628mer-1a153461855153461880145-20.93
CAediting_1526717chrX_153461664_-ENSG00000213397.9ENST00000370210hsa-miR-50931534616591534616657mer-m8153461658153461680141-11.77
CAediting_1526723chrX_153461844_-ENSG00000213397.9ENST00000370210hsa-miR-548at-5p1534618391534618457mer-m8153461838153461860141-14.2
CAediting_1526716chrX_153461644_-ENSG00000213397.9ENST00000370210hsa-miR-6506-3p1534616421534616487mer-m8153461641153461662142-11.07
CAediting_1526722chrX_153461825_-ENSG00000213397.9ENST00000370210hsa-miR-6740-5p1534618221534618287mer-m8153461821153461842140-18.6
CAediting_1526724chrX_153461861_-ENSG00000213397.9ENST00000370210hsa-miR-6808-3p1534618611534618677mer-m8153461860153461881150-18.14
CAediting_1526719chrX_153461764_-ENSG00000213397.9ENST00000370210hsa-miR-6874-5p1534617641534617707mer-m8153461763153461785140-15.67

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1229413chr17_67471544_+ENSG00000213397.9ENST00000370211hsa-miR-548aa1534476711534476777mer-m8153447670153447694152-14.44
CAediting_1229413chr17_67471544_+ENSG00000213397.9ENST00000435662hsa-miR-548aa1534476711534476777mer-m8153447670153447694152-14.44

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1229413chr17_67471544_+ENSG00000213397.9ENST00000370210hsa-miR-548aa1534619791534619857mer-m8153461978153462012153-23.33
CAediting_1229414chr17_67471546_+ENSG00000213397.9ENST00000370210hsa-miR-548aa1534619791534619857mer-m8153461978153462012153-23.33
CAediting_1229415chr17_67471547_+ENSG00000213397.9ENST00000370210hsa-miR-548aa1534619791534619857mer-m8153461978153462012153-23.33

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for HAUS7

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for HAUS7

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for HAUS7

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for HAUS7

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for HAUS7

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for HAUS7

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource