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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

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Relation with survival state

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Related drugs with this gene

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Related diseases with this gene

Editing gene: TMEM40 (CAeditome ID:55287)

Gene summary for TMEM40

check button Gene summary
Gene informationGene symbol

TMEM40

Gene ID

55287

Gene nametransmembrane protein 40
Synonyms-
Cytomap

3p25.2

Type of geneprotein-coding
Descriptiontransmembrane protein 40
Modification date20210518
UniProtAcc

Q8WWA1

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID

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RNA A-to-I events for TMEM40

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000088726.14

check button RNA A-to-I editing events in Cancer.
CAediting_259577(12733973, -), CAediting_259578(12734029, -), CAediting_259579(12734033, -), CAediting_259580(12734113, -), CAediting_259581(12734126, -), CAediting_259582(12734127, -), CAediting_259583(12734130, -), CAediting_259584(12734133, -), CAediting_259585(12734145, -), CAediting_259586(12734185, -), CAediting_259587(12734192, -), CAediting_259588(12738910, -), CAediting_259589(12738911, -), CAediting_259590(12738950, -), CAediting_259591(12738958, -), CAediting_259592(12738961, -), CAediting_259593(12738965, -), CAediting_259594(12738987, -), CAediting_259595(12738990, -), CAediting_259596(12739009, -), CAediting_259597(12739031, -), CAediting_259598(12739041, -), CAediting_259599(12739053, -), CAediting_259600(12739063, -), CAediting_259601(12739091, -), CAediting_259602(12739096, -), CAediting_259603(12739141, -), CAediting_259604(12739357, -), CAediting_259605(12739381, -), CAediting_259606(12739396, -), CAediting_259607(12739423, -), CAediting_259608(12739619, -), CAediting_259609(12739620, -), CAediting_259610(12739672, -), CAediting_259611(12739694, -), CAediting_259612(12739696, -), CAediting_259613(12739710, -), CAediting_259614(12739716, -), CAediting_259615(12739915, -), CAediting_259616(12739916, -), CAediting_259617(12739921, -), CAediting_259618(12739931, -), CAediting_259619(12739935, -), CAediting_259620(12739962, -), CAediting_259621(12740190, -), CAediting_259622(12740205, -), CAediting_259623(12740231, -), CAediting_259624(12740445, -), CAediting_259625(12740457, -), CAediting_259626(12740628, -), CAediting_259627(12740665, -), CAediting_259628(12740678, -), CAediting_259629(12740686, -), CAediting_259630(12740701, -), CAediting_259631(12740709, -), CAediting_259632(12740710, -), CAediting_259633(12740730, -), CAediting_259634(12740736, -), CAediting_259635(12740746, -), CAediting_259636(12740758, -), CAediting_259637(12740763, -), CAediting_259638(12740775, -), CAediting_259639(12740795, -), CAediting_259640(12740796, -), CAediting_259641(12740801, -), CAediting_259642(12740814, -), CAediting_259643(12740844, -), CAediting_259644(12741844, -), CAediting_259645(12741923, -), CAediting_259646(12741932, -), CAediting_259647(12741975, -), CAediting_259648(12741987, -), CAediting_259649(12743250, -), CAediting_259650(12743345, -), CAediting_259651(12743351, -), CAediting_259652(12743407, -), CAediting_259653(12743462, -), CAediting_259654(12745170, -), CAediting_259655(12745184, -), CAediting_259656(12745334, -), CAediting_259657(12745522, -), CAediting_259658(12745589, -), CAediting_259659(12745593, -), CAediting_259660(12745694, -), CAediting_259661(12745944, -), CAediting_259662(12745977, -), CAediting_259663(12745996, -), CAediting_259664(12746130, -), CAediting_259665(12751349, -), CAediting_259666(12751358, -), CAediting_259667(12751390, -), CAediting_259668(12751462, -), CAediting_259669(12752149, -), CAediting_259670(12752213, -), CAediting_259671(12752217, -), CAediting_259672(12752227, -), CAediting_259673(12752542, -), CAediting_259674(12752556, -), CAediting_259675(12752614, -), CAediting_259676(12752631, -), CAediting_259677(12752674, -), CAediting_259678(12752676, -), CAediting_259679(12752698, -), CAediting_259680(12753319, -), CAediting_259681(12753324, -), CAediting_259682(12753332, -), CAediting_259683(12753338, -), CAediting_259684(12753355, -), CAediting_259685(12753364, -), CAediting_259686(12753365, -), CAediting_259687(12753377, -), CAediting_259688(12753406, -), CAediting_259689(12753423, -), CAediting_259690(12753427, -), CAediting_259691(12753443, -), CAediting_259692(12753474, -), CAediting_259693(12753475, -), CAediting_259694(12753478, -), CAediting_259695(12753491, -), CAediting_259696(12754123, -), CAediting_259697(12754212, -), CAediting_259698(12757226, -), CAediting_259699(12757862, -),

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RNA editing positional annotations for TMEM40 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_259577chr3_12733973_-UTR3
CAediting_259578chr3_12734029_-UTR3
CAediting_259579chr3_12734033_-UTR3
CAediting_259580chr3_12734113_-UTR3
CAediting_259581chr3_12734126_-UTR3
CAediting_259582chr3_12734127_-UTR3
CAediting_259583chr3_12734130_-UTR3
CAediting_259584chr3_12734133_-UTR3
CAediting_259585chr3_12734145_-UTR3
CAediting_259586chr3_12734185_-UTR3
CAediting_259587chr3_12734192_-UTR3
CAediting_259588chr3_12738910_-ncRNA_exonic
CAediting_259589chr3_12738911_-ncRNA_exonic
CAediting_259590chr3_12738950_-ncRNA_exonic
CAediting_259591chr3_12738958_-ncRNA_exonic
CAediting_259592chr3_12738961_-ncRNA_exonic
CAediting_259593chr3_12738965_-ncRNA_exonic
CAediting_259594chr3_12738987_-ncRNA_exonic
CAediting_259595chr3_12738990_-ncRNA_exonic
CAediting_259596chr3_12739009_-ncRNA_exonic
CAediting_259597chr3_12739031_-ncRNA_exonic
CAediting_259598chr3_12739041_-ncRNA_exonic
CAediting_259599chr3_12739053_-ncRNA_exonic
CAediting_259600chr3_12739063_-ncRNA_exonic
CAediting_259601chr3_12739091_-ncRNA_exonic
CAediting_259602chr3_12739096_-ncRNA_exonic
CAediting_259603chr3_12739141_-ncRNA_exonic
CAediting_259604chr3_12739357_-ncRNA_intronic
CAediting_259605chr3_12739381_-ncRNA_intronic
CAediting_259606chr3_12739396_-ncRNA_intronic
CAediting_259607chr3_12739423_-ncRNA_intronic
CAediting_259608chr3_12739619_-ncRNA_intronic
CAediting_259609chr3_12739620_-ncRNA_intronic
CAediting_259610chr3_12739672_-ncRNA_intronic
CAediting_259611chr3_12739694_-ncRNA_intronic
CAediting_259612chr3_12739696_-ncRNA_intronic
CAediting_259613chr3_12739710_-ncRNA_intronic
CAediting_259614chr3_12739716_-ncRNA_intronic
CAediting_259615chr3_12739915_-ncRNA_intronic
CAediting_259616chr3_12739916_-ncRNA_intronic
CAediting_259617chr3_12739921_-ncRNA_intronic
CAediting_259618chr3_12739931_-ncRNA_intronic
CAediting_259619chr3_12739935_-ncRNA_intronic
CAediting_259620chr3_12739962_-ncRNA_intronic
CAediting_259621chr3_12740190_-ncRNA_intronic
CAediting_259622chr3_12740205_-ncRNA_intronic
CAediting_259623chr3_12740231_-ncRNA_intronic
CAediting_259624chr3_12740445_-ncRNA_intronic
CAediting_259625chr3_12740457_-ncRNA_intronic
CAediting_259626chr3_12740628_-ncRNA_intronic
CAediting_259627chr3_12740665_-ncRNA_intronic
CAediting_259628chr3_12740678_-ncRNA_intronic
CAediting_259629chr3_12740686_-ncRNA_intronic
CAediting_259630chr3_12740701_-ncRNA_intronic
CAediting_259631chr3_12740709_-ncRNA_intronic
CAediting_259632chr3_12740710_-ncRNA_intronic
CAediting_259633chr3_12740730_-ncRNA_intronic
CAediting_259634chr3_12740736_-ncRNA_intronic
CAediting_259635chr3_12740746_-ncRNA_intronic
CAediting_259636chr3_12740758_-ncRNA_intronic
CAediting_259637chr3_12740763_-ncRNA_intronic
CAediting_259638chr3_12740775_-ncRNA_intronic
CAediting_259639chr3_12740795_-ncRNA_intronic
CAediting_259640chr3_12740796_-ncRNA_intronic
CAediting_259641chr3_12740801_-ncRNA_intronic
CAediting_259642chr3_12740814_-ncRNA_intronic
CAediting_259643chr3_12740844_-ncRNA_intronic
CAediting_259644chr3_12741844_-intronic
CAediting_259645chr3_12741923_-intronic
CAediting_259646chr3_12741932_-intronic
CAediting_259647chr3_12741975_-intronic
CAediting_259648chr3_12741987_-intronic
CAediting_259649chr3_12743250_-intronic
CAediting_259650chr3_12743345_-intronic
CAediting_259651chr3_12743351_-intronic
CAediting_259652chr3_12743407_-intronic
CAediting_259653chr3_12743462_-intronic
CAediting_259654chr3_12745170_-intronic
CAediting_259655chr3_12745184_-intronic
CAediting_259656chr3_12745334_-intronic
CAediting_259657chr3_12745522_-intronic
CAediting_259658chr3_12745589_-intronic
CAediting_259659chr3_12745593_-intronic
CAediting_259660chr3_12745694_-intronic
CAediting_259661chr3_12745944_-intronic
CAediting_259662chr3_12745977_-intronic
CAediting_259663chr3_12745996_-intronic
CAediting_259664chr3_12746130_-intronic
CAediting_259665chr3_12751349_-intronic
CAediting_259666chr3_12751358_-intronic
CAediting_259667chr3_12751390_-intronic
CAediting_259668chr3_12751462_-intronic
CAediting_259669chr3_12752149_-intronic
CAediting_259670chr3_12752213_-intronic
CAediting_259671chr3_12752217_-intronic
CAediting_259672chr3_12752227_-intronic
CAediting_259673chr3_12752542_-intronic
CAediting_259674chr3_12752556_-intronic
CAediting_259675chr3_12752614_-intronic
CAediting_259676chr3_12752631_-intronic
CAediting_259677chr3_12752674_-intronic
CAediting_259678chr3_12752676_-intronic
CAediting_259679chr3_12752698_-intronic
CAediting_259680chr3_12753319_-intronic
CAediting_259681chr3_12753324_-intronic
CAediting_259682chr3_12753332_-intronic
CAediting_259683chr3_12753338_-intronic
CAediting_259684chr3_12753355_-intronic
CAediting_259685chr3_12753364_-intronic
CAediting_259686chr3_12753365_-intronic
CAediting_259687chr3_12753377_-intronic
CAediting_259688chr3_12753406_-intronic
CAediting_259689chr3_12753423_-intronic
CAediting_259690chr3_12753427_-intronic
CAediting_259691chr3_12753443_-intronic
CAediting_259692chr3_12753474_-intronic
CAediting_259693chr3_12753475_-intronic
CAediting_259694chr3_12753478_-intronic
CAediting_259695chr3_12753491_-intronic
CAediting_259696chr3_12754123_-intronic
CAediting_259697chr3_12754212_-intronic
CAediting_259698chr3_12757226_-intronic
CAediting_259699chr3_12757862_-intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_259577chr3_12733973_-SINEAluAluJr
CAediting_259578chr3_12734029_-SINEAluAluJr
CAediting_259579chr3_12734033_-SINEAluAluJr
CAediting_259580chr3_12734113_-SINEAluAluJr
CAediting_259581chr3_12734126_-SINEAluAluJr
CAediting_259582chr3_12734127_-SINEAluAluJr
CAediting_259583chr3_12734130_-SINEAluAluJr
CAediting_259584chr3_12734133_-SINEAluAluJr
CAediting_259585chr3_12734145_-SINEAluAluJr
CAediting_259586chr3_12734185_-SINEAluAluJr
CAediting_259587chr3_12734192_-SINEAluAluJr
CAediting_259588chr3_12738910_-SINEAluAluSc
CAediting_259589chr3_12738911_-SINEAluAluSc
CAediting_259590chr3_12738950_-SINEAluAluSc
CAediting_259591chr3_12738958_-SINEAluAluSc
CAediting_259592chr3_12738961_-SINEAluAluSc
CAediting_259593chr3_12738965_-SINEAluAluSc
CAediting_259594chr3_12738987_-SINEAluAluSc
CAediting_259595chr3_12738990_-SINEAluAluSc
CAediting_259596chr3_12739009_-SINEAluAluSc
CAediting_259597chr3_12739031_-SINEAluAluSc
CAediting_259598chr3_12739041_-SINEAluAluSc
CAediting_259599chr3_12739053_-SINEAluAluSc
CAediting_259600chr3_12739063_-SINEAluAluSc
CAediting_259601chr3_12739091_-SINEAluAluSc
CAediting_259602chr3_12739096_-SINEAluAluSc
CAediting_259603chr3_12739141_-SINEAluAluSc
CAediting_259604chr3_12739357_-SINEAluAluY
CAediting_259605chr3_12739381_-SINEAluAluY
CAediting_259606chr3_12739396_-SINEAluAluY
CAediting_259607chr3_12739423_-SINEAluAluY
CAediting_259608chr3_12739619_-SINEAluFLAM_C
CAediting_259609chr3_12739620_-SINEAluFLAM_C
CAediting_259610chr3_12739672_-SINEAluFLAM_C
CAediting_259611chr3_12739694_-SINEAluFLAM_C
CAediting_259612chr3_12739696_-SINEAluFLAM_C
CAediting_259613chr3_12739710_-SINEAluFLAM_C
CAediting_259615chr3_12739915_-SINEAluAluJo
CAediting_259616chr3_12739916_-SINEAluAluJo
CAediting_259617chr3_12739921_-SINEAluAluJo
CAediting_259618chr3_12739931_-SINEAluAluJo
CAediting_259619chr3_12739935_-SINEAluAluJo
CAediting_259620chr3_12739962_-SINEAluAluJo
CAediting_259621chr3_12740190_-SINEAluAluSz6
CAediting_259622chr3_12740205_-SINEAluAluSz6
CAediting_259623chr3_12740231_-SINEAluAluSz6
CAediting_259624chr3_12740445_-SINEAluAluY
CAediting_259625chr3_12740457_-SINEAluAluY
CAediting_259626chr3_12740628_-SINEAluAluSz
CAediting_259627chr3_12740665_-SINEAluAluSz
CAediting_259628chr3_12740678_-SINEAluAluSz
CAediting_259629chr3_12740686_-SINEAluAluSz
CAediting_259630chr3_12740701_-SINEAluAluSz
CAediting_259631chr3_12740709_-SINEAluAluSz
CAediting_259632chr3_12740710_-SINEAluAluSz
CAediting_259633chr3_12740730_-SINEAluAluSz
CAediting_259634chr3_12740736_-SINEAluAluSz
CAediting_259635chr3_12740746_-SINEAluAluSz
CAediting_259636chr3_12740758_-SINEAluAluSz
CAediting_259637chr3_12740763_-SINEAluAluSz
CAediting_259638chr3_12740775_-SINEAluAluSz
CAediting_259639chr3_12740795_-SINEAluAluSz
CAediting_259640chr3_12740796_-SINEAluAluSz
CAediting_259641chr3_12740801_-SINEAluAluSz
CAediting_259642chr3_12740814_-SINEAluAluSz
CAediting_259643chr3_12740844_-SINEAluAluSz
CAediting_259644chr3_12741844_-SINEAluAluJb
CAediting_259645chr3_12741923_-SINEAluAluJb
CAediting_259646chr3_12741932_-SINEAluAluJb
CAediting_259647chr3_12741975_-SINEAluAluSx3
CAediting_259648chr3_12741987_-SINEAluAluSx3
CAediting_259649chr3_12743250_-SINEAluAluSq2
CAediting_259650chr3_12743345_-SINEAluAluSq2
CAediting_259651chr3_12743351_-SINEAluAluSq2
CAediting_259652chr3_12743407_-SINEAluAluSq2
CAediting_259653chr3_12743462_-SINEAluAluSq2
CAediting_259654chr3_12745170_-SINEAluAluSq2
CAediting_259655chr3_12745184_-SINEAluAluSq2
CAediting_259656chr3_12745334_-SINEAluAluSq2
CAediting_259657chr3_12745522_-SINEAluAluJb
CAediting_259658chr3_12745589_-SINEAluAluJb
CAediting_259659chr3_12745593_-SINEAluAluJb
CAediting_259660chr3_12745694_-SINEAluAluJb
CAediting_259661chr3_12745944_-SINEAluAluSx1
CAediting_259662chr3_12745977_-SINEAluAluSx1
CAediting_259663chr3_12745996_-SINEAluAluSx1
CAediting_259664chr3_12746130_-SINEAluAluSx1
CAediting_259665chr3_12751349_-SINEAluAluSx4
CAediting_259666chr3_12751358_-SINEAluAluSx4
CAediting_259667chr3_12751390_-SINEAluAluSx4
CAediting_259668chr3_12751462_-SINEAluAluSx4
CAediting_259669chr3_12752149_-SINEAluAluJo
CAediting_259670chr3_12752213_-SINEAluAluJo
CAediting_259671chr3_12752217_-SINEAluAluJo
CAediting_259672chr3_12752227_-SINEAluAluJo
CAediting_259673chr3_12752542_-SINEAluAluSg
CAediting_259674chr3_12752556_-SINEAluAluSg
CAediting_259675chr3_12752614_-SINEAluAluSg
CAediting_259676chr3_12752631_-SINEAluAluSg
CAediting_259677chr3_12752674_-SINEAluAluSg
CAediting_259678chr3_12752676_-SINEAluAluSg
CAediting_259679chr3_12752698_-SINEAluAluSg
CAediting_259680chr3_12753319_-SINEAluAluJb
CAediting_259681chr3_12753324_-SINEAluAluJb
CAediting_259682chr3_12753332_-SINEAluAluJb
CAediting_259683chr3_12753338_-SINEAluAluJb
CAediting_259684chr3_12753355_-SINEAluAluJb
CAediting_259685chr3_12753364_-SINEAluAluJb
CAediting_259686chr3_12753365_-SINEAluAluJb
CAediting_259687chr3_12753377_-SINEAluAluJb
CAediting_259688chr3_12753406_-SINEAluAluJb
CAediting_259689chr3_12753423_-SINEAluAluJb
CAediting_259690chr3_12753427_-SINEAluAluJb
CAediting_259691chr3_12753443_-SINEAluAluJb
CAediting_259692chr3_12753474_-SINEAluAluJb
CAediting_259693chr3_12753475_-SINEAluAluJb
CAediting_259694chr3_12753478_-SINEAluAluJb
CAediting_259695chr3_12753491_-SINEAluAluJb
CAediting_259696chr3_12754123_-SINEAluAluY
CAediting_259697chr3_12754212_-SINEAluAluY
CAediting_259698chr3_12757226_-SINEAluAluSp
CAediting_259699chr3_12757862_-SINEAluAluSz

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RNA A-to-I editing events in the alternative splicing sites for TMEM40

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000088726.14.TMEM40.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000088726.14.TMEM40.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for TMEM40

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.
boxplot

check button Correlation between RNA A-to-I editing and gene expression.
boxplot

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for TMEM40

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for TMEM40

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435575hsa-miR-4716-5p12734112127341187mer-m81273411112734132148.00-14.09
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435575hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435575hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435575hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435575hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435575hsa-miR-6511b-3p12734107127341148mer-1a1273410712734129140.00-15.33
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435575hsa-miR-6511b-3p12734107127341148mer-1a1273410712734129140.00-15.33
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435218hsa-miR-4716-5p12734112127341187mer-m81273411112734132148.00-14.09
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435218hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435218hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435218hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435218hsa-miR-6511a-3p12734107127341148mer-1a1273410712734128145.00-16.88
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435218hsa-miR-6511b-3p12734107127341148mer-1a1273410712734129140.00-15.33
CAediting_259580chr3_12734113_-ENSG00000088726.14ENST00000435218hsa-miR-6511b-3p12734107127341148mer-1a1273410712734129140.00-15.33
CAediting_259587chr3_12734192_-ENSG00000088726.14ENST00000435575hsa-miR-444012734190127341956mer1273418912734214146.00-26.64
CAediting_259587chr3_12734192_-ENSG00000088726.14ENST00000435218hsa-miR-444012734190127341956mer1273418912734214146.00-26.64
CAediting_259578chr3_12734029_-ENSG00000088726.14ENST00000435575hsa-miR-516a-5p12734026127340327mer-m81273402512734047142.00-18.06
CAediting_259578chr3_12734029_-ENSG00000088726.14ENST00000435575hsa-miR-516a-5p12734026127340327mer-m81273402512734047142.00-18.06
CAediting_259578chr3_12734029_-ENSG00000088726.14ENST00000435218hsa-miR-516a-5p12734026127340327mer-m81273402512734047142.00-18.06
CAediting_259578chr3_12734029_-ENSG00000088726.14ENST00000435218hsa-miR-516a-5p12734026127340327mer-m81273402512734047142.00-18.06
CAediting_259579chr3_12734033_-ENSG00000088726.14ENST00000435575hsa-miR-1207-3p12734033127340397mer-m81273403212734050145.00-15.24
CAediting_259579chr3_12734033_-ENSG00000088726.14ENST00000435575hsa-miR-64612734031127340377mer-m81273403012734049148.00-22.42
CAediting_259579chr3_12734033_-ENSG00000088726.14ENST00000435218hsa-miR-1207-3p12734033127340397mer-m81273403212734050145.00-15.24
CAediting_259579chr3_12734033_-ENSG00000088726.14ENST00000435218hsa-miR-64612734031127340377mer-m81273403012734049148.00-22.42
CAediting_259581chr3_12734126_-ENSG00000088726.14ENST00000435575hsa-miR-3663-5p12734126127341327mer-m81273412512734141141.00-19.52
CAediting_259581chr3_12734126_-ENSG00000088726.14ENST00000435575hsa-miR-613112734125127341317mer-m81273412412734142140.00-17.94
CAediting_259581chr3_12734126_-ENSG00000088726.14ENST00000435218hsa-miR-3663-5p12734126127341327mer-m81273412512734141141.00-19.52
CAediting_259581chr3_12734126_-ENSG00000088726.14ENST00000435218hsa-miR-613112734125127341317mer-m81273412412734142140.00-17.94
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435575hsa-miR-139-5p12734185127341917mer-m81273418412734205151.00-22.09
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435575hsa-miR-475912734181127341877mer-m81273418012734200154.00-17.23
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435218hsa-miR-139-5p12734185127341917mer-m81273418412734205151.00-22.09
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435218hsa-miR-475912734181127341877mer-m81273418012734200154.00-17.23

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435575hsa-miR-10399-5p12734184127341907mer-m81273418312734202151-12.67
CAediting_259577chr3_12733973_-ENSG00000088726.14ENST00000435575hsa-miR-4777-3p12733973127339797mer-m81273397212733992150-15.44
CAediting_259577chr3_12733973_-ENSG00000088726.14ENST00000435575hsa-miR-487b-3p12733969127339757mer-m81273396812733989140-13.18
CAediting_259585chr3_12734145_-ENSG00000088726.14ENST00000435575hsa-miR-498-5p12734145127341517mer-m81273414412734166142-12.37
CAediting_259578chr3_12734029_-ENSG00000088726.14ENST00000435575hsa-miR-526b-5p12734026127340327mer-m81273402512734047140-19.92
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435575hsa-miR-6504-3p12734184127341907mer-m81273418312734202140-12.09
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435218hsa-miR-10399-5p12734184127341907mer-m81273418312734202151-12.67
CAediting_259577chr3_12733973_-ENSG00000088726.14ENST00000435218hsa-miR-4777-3p12733973127339797mer-m81273397212733992150-15.44
CAediting_259577chr3_12733973_-ENSG00000088726.14ENST00000435218hsa-miR-487b-3p12733969127339757mer-m81273396812733989140-13.18
CAediting_259585chr3_12734145_-ENSG00000088726.14ENST00000435218hsa-miR-498-5p12734145127341517mer-m81273414412734166142-12.37
CAediting_259578chr3_12734029_-ENSG00000088726.14ENST00000435218hsa-miR-526b-5p12734026127340327mer-m81273402512734047140-19.92
CAediting_259586chr3_12734185_-ENSG00000088726.14ENST00000435218hsa-miR-6504-3p12734184127341907mer-m81273418312734202140-12.09

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_1306324chr19_13836464_-ENSG00000088726.14ENST00000435575hsa-miR-27a-3p12734721127347277mer-m81273472012734740150-20.4
CAediting_393chr1_1167164_+ENSG00000088726.14ENST00000435575hsa-miR-200b-3p12734691127346977mer-m81273469012734712153-18.16
CAediting_1306324chr19_13836464_-ENSG00000088726.14ENST00000435218hsa-miR-27a-3p12734721127347277mer-m81273472012734740150-20.4
CAediting_393chr1_1167164_+ENSG00000088726.14ENST00000435218hsa-miR-200b-3p12734691127346977mer-m81273469012734712153-18.16
CAediting_1306324chr19_13836464_-ENSG00000088726.14ENST00000428020hsa-miR-27a-3p12734721127347277mer-m81273472012734740150-20.4
CAediting_393chr1_1167164_+ENSG00000088726.14ENST00000428020hsa-miR-200b-3p12734691127346977mer-m81273469012734712153-18.16
CAediting_1306324chr19_13836464_-ENSG00000088726.14ENST00000264728hsa-miR-27a-3p12734721127347277mer-m81273472012734740150-20.4
CAediting_1054808chr15_66496985_-ENSG00000088726.14ENST00000435575hsa-miR-451212734739127347468mer-1a1273473912734760156-27.44
CAediting_1054808chr15_66496985_-ENSG00000088726.14ENST00000435575hsa-miR-451212734310127343156mer1273430912734331142-23.88
CAediting_1054808chr15_66496985_-ENSG00000088726.14ENST00000435218hsa-miR-451212734739127347468mer-1a1273473912734760156-27.44
CAediting_1054808chr15_66496985_-ENSG00000088726.14ENST00000435218hsa-miR-451212734310127343156mer1273430912734331142-23.88
CAediting_1054808chr15_66496985_-ENSG00000088726.14ENST00000428020hsa-miR-451212734739127347468mer-1a1273473912734760156-27.44
CAediting_1054808chr15_66496985_-ENSG00000088726.14ENST00000264728hsa-miR-451212734739127347468mer-1a1273473912734760156-27.44

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_580943chr7_100356700_+ENSG00000088726.14ENST00000435575hsa-miR-6840-3p12734361127343688mer-1a1273436112734380147-22.11
CAediting_580943chr7_100356700_+ENSG00000088726.14ENST00000435218hsa-miR-6840-3p12734361127343688mer-1a1273436112734380147-22.11

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for TMEM40

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.
ENST00000314124.10protein_codingSoverviewSoverview
ENST00000435218.5protein_codingSoverviewSoverview
ENST00000435575.4protein_codingSoverviewSoverview
ENST00000485124.1retained_intronSoverviewSoverview

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI
CAediting_259577ENST00000314124.10chr3_12733973_--827.40-826.10-833.80
CAediting_259578ENST00000314124.10chr3_12734029_--826.30-826.10-833.80
CAediting_259579ENST00000314124.10chr3_12734033_--826.10-826.10-833.80
CAediting_259580ENST00000314124.10chr3_12734113_--826.60-826.10-833.80
CAediting_259581ENST00000314124.10chr3_12734126_--831.00-826.10-833.80
CAediting_259582ENST00000314124.10chr3_12734127_--829.70-826.10-833.80
CAediting_259583ENST00000314124.10chr3_12734130_--826.10-826.10-833.80
CAediting_259584ENST00000314124.10chr3_12734133_--825.80-826.10-833.80
CAediting_259585ENST00000314124.10chr3_12734145_--826.40-826.10-833.80
CAediting_259586ENST00000314124.10chr3_12734185_--827.90-826.10-833.80
CAediting_259587ENST00000314124.10chr3_12734192_--827.20-826.10-833.80
CAediting_259577ENST00000435218.5chr3_12733973_--572.10-570.80-579.00
CAediting_259578ENST00000435218.5chr3_12734029_--571.30-570.80-579.00
CAediting_259579ENST00000435218.5chr3_12734033_--570.80-570.80-579.00
CAediting_259580ENST00000435218.5chr3_12734113_--571.30-570.80-579.00
CAediting_259581ENST00000435218.5chr3_12734126_--575.70-570.80-579.00
CAediting_259582ENST00000435218.5chr3_12734127_--574.40-570.80-579.00
CAediting_259583ENST00000435218.5chr3_12734130_--570.80-570.80-579.00
CAediting_259584ENST00000435218.5chr3_12734133_--570.50-570.80-579.00
CAediting_259585ENST00000435218.5chr3_12734145_--571.10-570.80-579.00
CAediting_259586ENST00000435218.5chr3_12734185_--572.60-570.80-579.00
CAediting_259587ENST00000435218.5chr3_12734192_--571.90-570.80-579.00
CAediting_259577ENST00000435575.4chr3_12733973_--628.50-628.30-635.70
CAediting_259578ENST00000435575.4chr3_12734029_--628.80-628.30-635.70
CAediting_259579ENST00000435575.4chr3_12734033_--628.60-628.30-635.70
CAediting_259580ENST00000435575.4chr3_12734113_--628.80-628.30-635.70
CAediting_259581ENST00000435575.4chr3_12734126_--633.20-628.30-635.70
CAediting_259582ENST00000435575.4chr3_12734127_--631.90-628.30-635.70
CAediting_259583ENST00000435575.4chr3_12734130_--628.30-628.30-635.70
CAediting_259584ENST00000435575.4chr3_12734133_--628.00-628.30-635.70
CAediting_259585ENST00000435575.4chr3_12734145_--628.60-628.30-635.70
CAediting_259586ENST00000435575.4chr3_12734185_--630.10-628.30-635.70
CAediting_259587ENST00000435575.4chr3_12734192_--629.40-628.30-635.70
CAediting_259588ENST00000485124.1chr3_12738910_--331.40-324.80-340.50
CAediting_259589ENST00000485124.1chr3_12738911_--325.00-324.80-340.50
CAediting_259590ENST00000485124.1chr3_12738950_--324.10-324.80-340.50
CAediting_259591ENST00000485124.1chr3_12738958_--324.80-324.80-340.50
CAediting_259592ENST00000485124.1chr3_12738961_--324.40-324.80-340.50
CAediting_259593ENST00000485124.1chr3_12738965_--327.40-324.80-340.50
CAediting_259594ENST00000485124.1chr3_12738987_--326.00-324.80-340.50
CAediting_259595ENST00000485124.1chr3_12738990_--324.50-324.80-340.50
CAediting_259596ENST00000485124.1chr3_12739009_--324.80-324.80-340.50
CAediting_259597ENST00000485124.1chr3_12739031_--325.70-324.80-340.50
CAediting_259598ENST00000485124.1chr3_12739041_--329.10-324.80-340.50
CAediting_259599ENST00000485124.1chr3_12739053_--325.60-324.80-340.50
CAediting_259600ENST00000485124.1chr3_12739063_--324.00-324.80-340.50
CAediting_259601ENST00000485124.1chr3_12739091_--324.10-324.80-340.50
CAediting_259602ENST00000485124.1chr3_12739096_--324.40-324.80-340.50
CAediting_259603ENST00000485124.1chr3_12739141_--324.30-324.80-340.50

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Relation with ADAR for TMEM40

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)
BLCACAediting_259587chr3_12734192_-0.04365376843659690.2636176593306110.04088758177829040.267051326824362..

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Relation with cancer stages for TMEM40

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for TMEM40

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for TMEM40

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TMEM40

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource