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Editing gene: MRPS10 (CAeditome ID:55173)

Gene summary for MRPS10

Gene summary

Gene information	Gene symbol	MRPS10
	Gene ID	55173
	Gene name	mitochondrial ribosomal protein S10
	Synonyms	MRP-S10\|PNAS-122
	Cytomap	6p21.1
	Type of gene	protein-coding
	Description	28S ribosomal protein S10, mitochondrialS10mtmitochondrial 28S ribosomal protein S10mitochondrial small ribosomal subunit protein uS10m
	Modification date	20210518
	UniProtAcc	P82664
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
MRPS10	GO:0005763	28S ribosomal protein S10, mitochondrial	25838379

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RNA A-to-I events for MRPS10

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000048544.5

RNA A-to-I editing events in Cancer.

CAediting_480720(42207223, -), CAediting_480721(42207224, -), CAediting_480722(42207254, -), CAediting_480723(42207256, -), CAediting_480724(42207277, -), CAediting_480725(42207296, -), CAediting_480726(42207318, -), CAediting_480727(42207319, -), CAediting_480728(42207333, -), CAediting_480729(42207343, -), CAediting_480730(42207346, -), CAediting_480731(42207350, -), CAediting_480732(42207354, -), CAediting_480733(42207359, -), CAediting_480734(42207360, -), CAediting_480735(42207386, -), CAediting_480736(42207389, -), CAediting_480737(42207390, -), CAediting_480738(42207392, -), CAediting_480739(42207395, -), CAediting_480740(42207398, -), CAediting_480741(42207399, -), CAediting_480742(42207401, -), CAediting_480743(42207404, -), CAediting_480744(42207415, -), CAediting_480745(42207416, -), CAediting_480746(42207426, -), CAediting_480747(42207448, -), CAediting_480748(42207454, -), CAediting_480749(42207457, -), CAediting_480750(42207466, -), CAediting_480751(42207484, -), CAediting_480752(42207487, -), CAediting_480753(42207492, -), CAediting_480754(42207493, -), CAediting_480755(42207501, -), CAediting_480756(42207511, -), CAediting_480757(42207515, -), CAediting_480758(42209088, -), CAediting_480759(42209093, -), CAediting_480760(42209109, -), CAediting_480761(42209636, -), CAediting_480762(42215274, -), CAediting_480763(42215277, -), CAediting_480764(42215281, -), CAediting_480765(42216054, -), CAediting_480766(42216120, -), CAediting_480767(42216121, -), CAediting_480768(42216139, -), CAediting_480769(42216140, -), CAediting_480770(42216148, -), CAediting_480771(42216152, -), CAediting_480772(42216162, -), CAediting_480773(42216188, -), CAediting_480774(42216202, -), CAediting_480775(42216203, -), CAediting_480776(42216206, -), CAediting_480777(42216219, -), CAediting_480778(42216220, -), CAediting_480779(42216227, -), CAediting_480780(42216294, -), CAediting_480781(42216295, -), CAediting_480782(42216554, -), CAediting_480783(42216631, -), CAediting_480784(42216641, -), CAediting_480785(42216645, -), CAediting_480786(42216648, -), CAediting_480787(42216663, -), CAediting_480788(42216711, -), CAediting_480789(42216716, -), CAediting_480790(42216751, -), CAediting_480791(42216784, -),

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RNA editing positional annotations for MRPS10 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_480720	chr6_42207223_-	UTR3
CAediting_480721	chr6_42207224_-	UTR3
CAediting_480722	chr6_42207254_-	UTR3
CAediting_480723	chr6_42207256_-	UTR3
CAediting_480724	chr6_42207277_-	UTR3
CAediting_480725	chr6_42207296_-	UTR3
CAediting_480726	chr6_42207318_-	UTR3
CAediting_480727	chr6_42207319_-	UTR3
CAediting_480728	chr6_42207333_-	UTR3
CAediting_480729	chr6_42207343_-	UTR3
CAediting_480730	chr6_42207346_-	UTR3
CAediting_480731	chr6_42207350_-	UTR3
CAediting_480732	chr6_42207354_-	UTR3
CAediting_480733	chr6_42207359_-	UTR3
CAediting_480734	chr6_42207360_-	UTR3
CAediting_480735	chr6_42207386_-	UTR3
CAediting_480736	chr6_42207389_-	UTR3
CAediting_480737	chr6_42207390_-	UTR3
CAediting_480738	chr6_42207392_-	UTR3
CAediting_480739	chr6_42207395_-	UTR3
CAediting_480740	chr6_42207398_-	UTR3
CAediting_480741	chr6_42207399_-	UTR3
CAediting_480742	chr6_42207401_-	UTR3
CAediting_480743	chr6_42207404_-	UTR3
CAediting_480744	chr6_42207415_-	UTR3
CAediting_480745	chr6_42207416_-	UTR3
CAediting_480746	chr6_42207426_-	UTR3
CAediting_480747	chr6_42207448_-	UTR3
CAediting_480748	chr6_42207454_-	UTR3
CAediting_480749	chr6_42207457_-	UTR3
CAediting_480750	chr6_42207466_-	UTR3
CAediting_480751	chr6_42207484_-	UTR3
CAediting_480752	chr6_42207487_-	UTR3
CAediting_480753	chr6_42207492_-	UTR3
CAediting_480754	chr6_42207493_-	UTR3
CAediting_480755	chr6_42207501_-	UTR3
CAediting_480756	chr6_42207511_-	UTR3
CAediting_480757	chr6_42207515_-	UTR3
CAediting_480758	chr6_42209088_-	intronic
CAediting_480759	chr6_42209093_-	intronic
CAediting_480760	chr6_42209109_-	intronic
CAediting_480761	chr6_42209636_-	intronic
CAediting_480762	chr6_42215274_-	intronic
CAediting_480763	chr6_42215277_-	intronic
CAediting_480764	chr6_42215281_-	intronic
CAediting_480765	chr6_42216054_-	intronic
CAediting_480766	chr6_42216120_-	intronic
CAediting_480767	chr6_42216121_-	intronic
CAediting_480768	chr6_42216139_-	intronic
CAediting_480769	chr6_42216140_-	intronic
CAediting_480770	chr6_42216148_-	intronic
CAediting_480771	chr6_42216152_-	intronic
CAediting_480772	chr6_42216162_-	intronic
CAediting_480773	chr6_42216188_-	intronic
CAediting_480774	chr6_42216202_-	intronic
CAediting_480775	chr6_42216203_-	intronic
CAediting_480776	chr6_42216206_-	intronic
CAediting_480777	chr6_42216219_-	intronic
CAediting_480778	chr6_42216220_-	intronic
CAediting_480779	chr6_42216227_-	intronic
CAediting_480780	chr6_42216294_-	intronic
CAediting_480781	chr6_42216295_-	intronic
CAediting_480782	chr6_42216554_-	intronic
CAediting_480783	chr6_42216631_-	intronic
CAediting_480784	chr6_42216641_-	intronic
CAediting_480785	chr6_42216645_-	intronic
CAediting_480786	chr6_42216648_-	intronic
CAediting_480787	chr6_42216663_-	intronic
CAediting_480788	chr6_42216711_-	intronic
CAediting_480789	chr6_42216716_-	intronic
CAediting_480790	chr6_42216751_-	intronic
CAediting_480791	chr6_42216784_-	intronic

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_480720	chr6_42207223_-	SINE	Alu	AluSc
CAediting_480721	chr6_42207224_-	SINE	Alu	AluSc
CAediting_480722	chr6_42207254_-	SINE	Alu	AluSc
CAediting_480723	chr6_42207256_-	SINE	Alu	AluSc
CAediting_480724	chr6_42207277_-	SINE	Alu	AluSc
CAediting_480725	chr6_42207296_-	SINE	Alu	AluSc
CAediting_480726	chr6_42207318_-	SINE	Alu	AluSc
CAediting_480727	chr6_42207319_-	SINE	Alu	AluSc
CAediting_480728	chr6_42207333_-	SINE	Alu	AluSc
CAediting_480729	chr6_42207343_-	SINE	Alu	AluSc
CAediting_480730	chr6_42207346_-	SINE	Alu	AluSc
CAediting_480731	chr6_42207350_-	SINE	Alu	AluSc
CAediting_480732	chr6_42207354_-	SINE	Alu	AluSc
CAediting_480733	chr6_42207359_-	SINE	Alu	AluSc
CAediting_480734	chr6_42207360_-	SINE	Alu	AluSc
CAediting_480735	chr6_42207386_-	SINE	Alu	AluSc
CAediting_480736	chr6_42207389_-	SINE	Alu	AluSc
CAediting_480737	chr6_42207390_-	SINE	Alu	AluSc
CAediting_480738	chr6_42207392_-	SINE	Alu	AluSc
CAediting_480739	chr6_42207395_-	SINE	Alu	AluSc
CAediting_480740	chr6_42207398_-	SINE	Alu	AluSc
CAediting_480741	chr6_42207399_-	SINE	Alu	AluSc
CAediting_480742	chr6_42207401_-	SINE	Alu	AluSc
CAediting_480743	chr6_42207404_-	SINE	Alu	AluSc
CAediting_480744	chr6_42207415_-	SINE	Alu	AluSc
CAediting_480745	chr6_42207416_-	SINE	Alu	AluSc
CAediting_480746	chr6_42207426_-	SINE	Alu	AluSc
CAediting_480747	chr6_42207448_-	SINE	Alu	AluSc
CAediting_480748	chr6_42207454_-	SINE	Alu	AluSc
CAediting_480749	chr6_42207457_-	SINE	Alu	AluSc
CAediting_480750	chr6_42207466_-	SINE	Alu	AluSc
CAediting_480751	chr6_42207484_-	SINE	Alu	AluSc
CAediting_480752	chr6_42207487_-	SINE	Alu	AluSc
CAediting_480753	chr6_42207492_-	SINE	Alu	AluSc
CAediting_480754	chr6_42207493_-	SINE	Alu	AluSc
CAediting_480755	chr6_42207501_-	SINE	Alu	AluSc
CAediting_480756	chr6_42207511_-	SINE	Alu	AluSc
CAediting_480757	chr6_42207515_-	SINE	Alu	AluSc
CAediting_480758	chr6_42209088_-	SINE	Alu	AluSz
CAediting_480759	chr6_42209093_-	SINE	Alu	AluSz
CAediting_480760	chr6_42209109_-	SINE	Alu	AluSz
CAediting_480761	chr6_42209636_-	SINE	Alu	AluSx
CAediting_480762	chr6_42215274_-	SINE	Alu	AluSz
CAediting_480763	chr6_42215277_-	SINE	Alu	AluSz
CAediting_480764	chr6_42215281_-	SINE	Alu	AluSz
CAediting_480765	chr6_42216054_-	SINE	Alu	AluSg
CAediting_480766	chr6_42216120_-	SINE	Alu	AluSg
CAediting_480767	chr6_42216121_-	SINE	Alu	AluSg
CAediting_480768	chr6_42216139_-	SINE	Alu	AluSg
CAediting_480769	chr6_42216140_-	SINE	Alu	AluSg
CAediting_480770	chr6_42216148_-	SINE	Alu	AluSg
CAediting_480771	chr6_42216152_-	SINE	Alu	AluSg
CAediting_480772	chr6_42216162_-	SINE	Alu	AluSg
CAediting_480773	chr6_42216188_-	SINE	Alu	AluSg
CAediting_480774	chr6_42216202_-	SINE	Alu	AluSg
CAediting_480775	chr6_42216203_-	SINE	Alu	AluSg
CAediting_480776	chr6_42216206_-	SINE	Alu	AluSg
CAediting_480777	chr6_42216219_-	SINE	Alu	AluSg
CAediting_480778	chr6_42216220_-	SINE	Alu	AluSg
CAediting_480779	chr6_42216227_-	SINE	Alu	AluSg
CAediting_480780	chr6_42216294_-	SINE	Alu	AluSg
CAediting_480781	chr6_42216295_-	SINE	Alu	AluSg
CAediting_480782	chr6_42216554_-	SINE	Alu	AluSq2
CAediting_480783	chr6_42216631_-	SINE	Alu	AluSq2
CAediting_480784	chr6_42216641_-	SINE	Alu	AluSq2
CAediting_480785	chr6_42216645_-	SINE	Alu	AluSq2
CAediting_480786	chr6_42216648_-	SINE	Alu	AluSq2
CAediting_480787	chr6_42216663_-	SINE	Alu	AluSq2
CAediting_480788	chr6_42216711_-	SINE	Alu	AluSq2
CAediting_480789	chr6_42216716_-	SINE	Alu	AluSq2
CAediting_480790	chr6_42216751_-	SINE	Alu	AluSq2
CAediting_480791	chr6_42216784_-	SINE	Alu	AluSq2

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RNA A-to-I editing events in the alternative splicing sites for MRPS10

RNA A-to-I editing(s) in the alternative splicing sites.

AStype

CAeditomID

Editing position

AS position

AS direction

Exonic location

Wildtype sequence

Wildtype splicing strength

RNA edited sequence

RNA edited splicing strength

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000048544.5.MRPS10.

Correlation between RNA A-to-I editing and PSI for ENSG00000048544.5.MRPS10.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for MRPS10

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for MRPS10

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for MRPS10

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for MRPS10

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST	ENST type	RNA structure without RNA A-to-I editing.	RNA structure with RNA A-to-I editing.
ENST00000053468.3	protein_coding

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID	ENST	Editing_Position	MFE_withoneAI	MFE_withoutAI	MFE_withmultipleAI
CAediting_480720	ENST00000053468.3	chr6_42207223_-	-589.70	-588.60	-630.30
CAediting_480721	ENST00000053468.3	chr6_42207224_-	-588.10	-588.60	-630.30
CAediting_480722	ENST00000053468.3	chr6_42207254_-	-592.10	-588.60	-630.30
CAediting_480723	ENST00000053468.3	chr6_42207256_-	-592.10	-588.60	-630.30
CAediting_480724	ENST00000053468.3	chr6_42207277_-	-588.20	-588.60	-630.30
CAediting_480725	ENST00000053468.3	chr6_42207296_-	-587.90	-588.60	-630.30
CAediting_480726	ENST00000053468.3	chr6_42207318_-	-591.80	-588.60	-630.30
CAediting_480727	ENST00000053468.3	chr6_42207319_-	-589.60	-588.60	-630.30
CAediting_480728	ENST00000053468.3	chr6_42207333_-	-591.50	-588.60	-630.30
CAediting_480729	ENST00000053468.3	chr6_42207343_-	-589.40	-588.60	-630.30
CAediting_480730	ENST00000053468.3	chr6_42207346_-	-590.10	-588.60	-630.30
CAediting_480731	ENST00000053468.3	chr6_42207350_-	-588.30	-588.60	-630.30
CAediting_480732	ENST00000053468.3	chr6_42207354_-	-588.90	-588.60	-630.30
CAediting_480733	ENST00000053468.3	chr6_42207359_-	-589.50	-588.60	-630.30
CAediting_480734	ENST00000053468.3	chr6_42207360_-	-589.10	-588.60	-630.30
CAediting_480735	ENST00000053468.3	chr6_42207386_-	-588.30	-588.60	-630.30
CAediting_480736	ENST00000053468.3	chr6_42207389_-	-589.40	-588.60	-630.30
CAediting_480737	ENST00000053468.3	chr6_42207390_-	-590.20	-588.60	-630.30
CAediting_480738	ENST00000053468.3	chr6_42207392_-	-588.60	-588.60	-630.30
CAediting_480739	ENST00000053468.3	chr6_42207395_-	-588.60	-588.60	-630.30
CAediting_480740	ENST00000053468.3	chr6_42207398_-	-592.30	-588.60	-630.30
CAediting_480741	ENST00000053468.3	chr6_42207399_-	-589.10	-588.60	-630.30
CAediting_480742	ENST00000053468.3	chr6_42207401_-	-589.80	-588.60	-630.30
CAediting_480743	ENST00000053468.3	chr6_42207404_-	-589.90	-588.60	-630.30
CAediting_480744	ENST00000053468.3	chr6_42207415_-	-589.10	-588.60	-630.30
CAediting_480745	ENST00000053468.3	chr6_42207416_-	-590.80	-588.60	-630.30
CAediting_480746	ENST00000053468.3	chr6_42207426_-	-589.40	-588.60	-630.30
CAediting_480747	ENST00000053468.3	chr6_42207448_-	-591.30	-588.60	-630.30
CAediting_480748	ENST00000053468.3	chr6_42207454_-	-588.60	-588.60	-630.30
CAediting_480749	ENST00000053468.3	chr6_42207457_-	-591.60	-588.60	-630.30
CAediting_480750	ENST00000053468.3	chr6_42207466_-	-591.20	-588.60	-630.30
CAediting_480751	ENST00000053468.3	chr6_42207484_-	-590.00	-588.60	-630.30
CAediting_480752	ENST00000053468.3	chr6_42207487_-	-589.40	-588.60	-630.30
CAediting_480753	ENST00000053468.3	chr6_42207492_-	-588.60	-588.60	-630.30
CAediting_480754	ENST00000053468.3	chr6_42207493_-	-589.60	-588.60	-630.30
CAediting_480755	ENST00000053468.3	chr6_42207501_-	-590.10	-588.60	-630.30
CAediting_480756	ENST00000053468.3	chr6_42207511_-	-589.60	-588.60	-630.30
CAediting_480757	ENST00000053468.3	chr6_42207515_-	-591.60	-588.60	-630.30

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Relation with ADAR for MRPS10

Correlation between ADAR gene expression and RNA editing frequency

Cancer

CAeditomID

position

ADAR1 (p-val)

ADAR1 (coeff.)

ADAR2 (p-val)

ADAR2 (coeff.)

ADAR3 (p-val)

ADAR3 (coeff.)

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Relation with cancer stages for MRPS10

Correlation between Cancer stages and RNA editing frequency

Cancer

Stage_type

CAeditomID

position

P-val

Coeff.

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Relation with survival for MRPS10

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for MRPS10

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for MRPS10

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene