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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

RNA A-to-I events

Soverview

Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples

Soverview

Protein coding region RNA A-to-I editings

Soverview

The effects of the RNA editing to the miRNA binding sites

Soverview

The effects of the RNA editing to the stability of the RNA structures

Soverview

Relation with ADAR

Soverview

Relation with cancer stages

Soverview

Relation with survival state

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Editing gene: CEP192 (CAeditome ID:55125)

Gene summary for CEP192

check button Gene summary
Gene informationGene symbol

CEP192

Gene ID

55125

Gene namecentrosomal protein 192
SynonymsPPP1R62
Cytomap

18p11.21

Type of geneprotein-coding
Descriptioncentrosomal protein of 192 kDa192 kDa centrosomal proteincentrosomal protein 192kDacep192/SPD-2protein phosphatase 1, regulatory subunit 62
Modification date20210518
UniProtAcc

Q8TEP8

Context

check button Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez
GeneGO IDGO termPubMed ID
CEP192

GO:0019902

Centrosomal protein of 192 kDa

19389623

CEP192

GO:0005813

Centrosomal protein of 192 kDa

0000052

CEP192

GO:0005813

Centrosomal protein of 192 kDa

17980596

CEP192

GO:0005813

Centrosomal protein of 192 kDa

19543530

CEP192

GO:0005813

Centrosomal protein of 192 kDa

21399614

CEP192

GO:0005814

Centrosomal protein of 192 kDa

32060285

CEP192

GO:0005829

Centrosomal protein of 192 kDa

0000052


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RNA A-to-I events for CEP192

check buttonRNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.
all structure

check button RNA editing frequencies across 33 cancers of gene: ENSG00000101639.17
boxplot

check button RNA A-to-I editing events in Cancer.
CAediting_1254926(12993490, +), CAediting_1254927(12997778, +), CAediting_1254928(13001773, +), CAediting_1254929(13003278, +), CAediting_1254930(13008852, +), CAediting_1254931(13008854, +), CAediting_1254932(13009713, +), CAediting_1254933(13010022, +), CAediting_1254934(13010038, +), CAediting_1254935(13010048, +), CAediting_1254936(13010731, +), CAediting_1254937(13010735, +), CAediting_1254938(13010971, +), CAediting_1254939(13010972, +), CAediting_1254940(13011012, +), CAediting_1254941(13011062, +), CAediting_1254942(13011065, +), CAediting_1254943(13011080, +), CAediting_1254944(13011106, +), CAediting_1254945(13011116, +), CAediting_1254946(13011683, +), CAediting_1254947(13037655, +), CAediting_1254948(13037717, +), CAediting_1254949(13041664, +), CAediting_1254950(13041677, +), CAediting_1254951(13041730, +), CAediting_1254952(13064379, +), CAediting_1254953(13075912, +), CAediting_1254954(13076265, +), CAediting_1254955(13076993, +), CAediting_1254956(13077259, +), CAediting_1254957(13077260, +), CAediting_1254958(13104532, +), CAediting_1254959(13108657, +), CAediting_1254960(13108754, +), CAediting_1254961(13111225, +), CAediting_1254962(13116659, +), CAediting_1254963(13116660, +), CAediting_1254964(13116945, +), CAediting_1254965(13116951, +), CAediting_1254966(13116961, +), CAediting_1254967(13116967, +), CAediting_1254968(13116968, +), CAediting_1254969(13116972, +), CAediting_1254970(13116988, +), CAediting_1254971(13116989, +), CAediting_1254972(13117015, +), CAediting_1254973(13117023, +), CAediting_1254974(13117026, +), CAediting_1254975(13117027, +), CAediting_1254976(13117040, +), CAediting_1254977(13117073, +), CAediting_1254978(13117074, +), CAediting_1254979(13117077, +), CAediting_1254980(13117078, +), CAediting_1254981(13117085, +), CAediting_1254982(13117093, +), CAediting_1254983(13117103, +), CAediting_1254984(13117109, +), CAediting_1254985(13122474, +), CAediting_1254986(13124039, +), CAediting_1254987(13124040, +), CAediting_1254988(13124095, +), CAediting_1254989(13124109, +),

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RNA editing positional annotations for CEP192 using Annovar

check button Protein coding RNA editing(s).
CAeditome IDPositionVariant typeENSTNTchangeAAchangeSIFT_scorePolyphen2_HVAR_scorePROVEAN_pred

check button Gene structure information of RNA editing(s).
CAeditome IDPositionVariant type
CAediting_1254926chr18_12993490_+intronic
CAediting_1254927chr18_12997778_+intronic
CAediting_1254928chr18_13001773_+intronic
CAediting_1254929chr18_13003278_+intronic
CAediting_1254930chr18_13008852_+intronic
CAediting_1254931chr18_13008854_+intronic
CAediting_1254932chr18_13009713_+intronic
CAediting_1254933chr18_13010022_+intronic
CAediting_1254934chr18_13010038_+intronic
CAediting_1254935chr18_13010048_+intronic
CAediting_1254936chr18_13010731_+intronic
CAediting_1254937chr18_13010735_+intronic
CAediting_1254938chr18_13010971_+intronic
CAediting_1254939chr18_13010972_+intronic
CAediting_1254940chr18_13011012_+intronic
CAediting_1254941chr18_13011062_+intronic
CAediting_1254942chr18_13011065_+intronic
CAediting_1254943chr18_13011080_+intronic
CAediting_1254944chr18_13011106_+intronic
CAediting_1254945chr18_13011116_+intronic
CAediting_1254946chr18_13011683_+intronic
CAediting_1254947chr18_13037655_+intronic
CAediting_1254948chr18_13037717_+intronic
CAediting_1254949chr18_13041664_+intronic
CAediting_1254950chr18_13041677_+intronic
CAediting_1254951chr18_13041730_+intronic
CAediting_1254952chr18_13064379_+intronic
CAediting_1254953chr18_13075912_+ncRNA_intronic
CAediting_1254954chr18_13076265_+ncRNA_intronic
CAediting_1254955chr18_13076993_+ncRNA_intronic
CAediting_1254956chr18_13077259_+ncRNA_intronic
CAediting_1254957chr18_13077260_+ncRNA_intronic
CAediting_1254958chr18_13104532_+ncRNA_intronic
CAediting_1254959chr18_13108657_+ncRNA_intronic
CAediting_1254960chr18_13108754_+ncRNA_intronic
CAediting_1254961chr18_13111225_+ncRNA_intronic
CAediting_1254962chr18_13116659_+ncRNA_intronic
CAediting_1254963chr18_13116660_+ncRNA_intronic
CAediting_1254964chr18_13116945_+ncRNA_intronic
CAediting_1254965chr18_13116951_+ncRNA_intronic
CAediting_1254966chr18_13116961_+ncRNA_intronic
CAediting_1254967chr18_13116967_+ncRNA_intronic
CAediting_1254968chr18_13116968_+ncRNA_intronic
CAediting_1254969chr18_13116972_+ncRNA_intronic
CAediting_1254970chr18_13116988_+ncRNA_intronic
CAediting_1254971chr18_13116989_+ncRNA_intronic
CAediting_1254972chr18_13117015_+ncRNA_intronic
CAediting_1254973chr18_13117023_+ncRNA_intronic
CAediting_1254974chr18_13117026_+ncRNA_intronic
CAediting_1254975chr18_13117027_+ncRNA_intronic
CAediting_1254976chr18_13117040_+ncRNA_intronic
CAediting_1254977chr18_13117073_+ncRNA_intronic
CAediting_1254978chr18_13117074_+ncRNA_intronic
CAediting_1254979chr18_13117077_+ncRNA_intronic
CAediting_1254980chr18_13117078_+ncRNA_intronic
CAediting_1254981chr18_13117085_+ncRNA_intronic
CAediting_1254982chr18_13117093_+ncRNA_intronic
CAediting_1254983chr18_13117103_+ncRNA_intronic
CAediting_1254984chr18_13117109_+ncRNA_intronic
CAediting_1254985chr18_13122474_+ncRNA_intronic
CAediting_1254986chr18_13124039_+ncRNA_intronic
CAediting_1254987chr18_13124040_+ncRNA_intronic
CAediting_1254988chr18_13124095_+ncRNA_intronic
CAediting_1254989chr18_13124109_+ncRNA_intronic

check button Repat-regional RNA editing(s).
CAeditome IDPositionRepeat familyRepeat sub familyRepeat name
CAediting_1254926chr18_12993490_+SINEAluFAM
CAediting_1254927chr18_12997778_+SINEAluAluSx1
CAediting_1254928chr18_13001773_+SINEAluAluSz
CAediting_1254929chr18_13003278_+SINEAluAluSx
CAediting_1254930chr18_13008852_+SINEAluAluJb
CAediting_1254931chr18_13008854_+SINEAluAluJb
CAediting_1254932chr18_13009713_+SINEAluAluSx1
CAediting_1254933chr18_13010022_+SINEAluAluJb
CAediting_1254934chr18_13010038_+SINEAluAluJb
CAediting_1254935chr18_13010048_+SINEAluAluJb
CAediting_1254936chr18_13010731_+SINEAluAluSp
CAediting_1254937chr18_13010735_+SINEAluAluSp
CAediting_1254938chr18_13010971_+SINEAluAluSx1
CAediting_1254939chr18_13010972_+SINEAluAluSx1
CAediting_1254940chr18_13011012_+SINEAluAluSx1
CAediting_1254941chr18_13011062_+SINEAluAluSx1
CAediting_1254942chr18_13011065_+SINEAluAluSx1
CAediting_1254943chr18_13011080_+SINEAluAluSx1
CAediting_1254944chr18_13011106_+SINEAluAluSx1
CAediting_1254945chr18_13011116_+SINEAluAluSx1
CAediting_1254946chr18_13011683_+SINEAluAluSz
CAediting_1254947chr18_13037655_+SINEAluAluJo
CAediting_1254948chr18_13037717_+SINEAluAluJo
CAediting_1254949chr18_13041664_+SINEAluAluSz
CAediting_1254950chr18_13041677_+SINEAluAluSz
CAediting_1254951chr18_13041730_+SINEAluAluSz
CAediting_1254952chr18_13064379_+SINEAluAluY
CAediting_1254954chr18_13076265_+SINEAluAluSc
CAediting_1254955chr18_13076993_+SINEAluAluSx1
CAediting_1254956chr18_13077259_+DNATcMar-TiggerTigger4a
CAediting_1254957chr18_13077260_+DNATcMar-TiggerTigger4a
CAediting_1254958chr18_13104532_+SINEAluAluJr
CAediting_1254959chr18_13108657_+SINEAluAluSx3
CAediting_1254960chr18_13108754_+SINEAluAluSx3
CAediting_1254961chr18_13111225_+SINEAluAluSc8
CAediting_1254962chr18_13116659_+SINEAluAluY
CAediting_1254963chr18_13116660_+SINEAluAluY
CAediting_1254964chr18_13116945_+SINEAluAluJb
CAediting_1254965chr18_13116951_+SINEAluAluJb
CAediting_1254966chr18_13116961_+SINEAluAluJb
CAediting_1254967chr18_13116967_+SINEAluAluJb
CAediting_1254968chr18_13116968_+SINEAluAluJb
CAediting_1254969chr18_13116972_+SINEAluAluJb
CAediting_1254970chr18_13116988_+SINEAluAluJb
CAediting_1254971chr18_13116989_+SINEAluAluJb
CAediting_1254972chr18_13117015_+SINEAluAluJb
CAediting_1254973chr18_13117023_+SINEAluAluJb
CAediting_1254974chr18_13117026_+SINEAluAluJb
CAediting_1254975chr18_13117027_+SINEAluAluJb
CAediting_1254976chr18_13117040_+SINEAluAluJb
CAediting_1254977chr18_13117073_+SINEAluAluJb
CAediting_1254978chr18_13117074_+SINEAluAluJb
CAediting_1254979chr18_13117077_+SINEAluAluJb
CAediting_1254980chr18_13117078_+SINEAluAluJb
CAediting_1254981chr18_13117085_+SINEAluAluJb
CAediting_1254982chr18_13117093_+SINEAluAluJb
CAediting_1254983chr18_13117103_+SINEAluAluJb
CAediting_1254984chr18_13117109_+SINEAluAluJb
CAediting_1254985chr18_13122474_+SINEAluAluSx
CAediting_1254986chr18_13124039_+SINEAluAluSq2
CAediting_1254987chr18_13124040_+SINEAluAluSq2
CAediting_1254988chr18_13124095_+SINEAluAluSq2
CAediting_1254989chr18_13124109_+SINEAluAluSq2

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RNA A-to-I editing events in the alternative splicing sites for CEP192

check button RNA A-to-I editing(s) in the alternative splicing sites.
AStypeCAeditomIDEditing positionAS positionAS directionExonic locationWildtype sequenceWildtype splicing strengthRNA edited sequenceRNA edited splicing strength

check button Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000101639.17.CEP192.

check button Correlation between RNA A-to-I editing and PSI for ENSG00000101639.17.CEP192.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for CEP192

check button Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

check button Correlation between RNA A-to-I editing and gene expression.

check button - Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

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Protein coding region RNA A-to-I editings for CEP192

check button- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.


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The effects of the RNA editing to the miRNA binding sites for CEP192

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

check button RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA gained miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in lncRNA lost miRNA binding sites.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs lost binding to lncRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy

check button RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_688080chr9_63819626_+ENSG00000101639.17ENST00000513432hsa-miR-4477b13049377130493848mer-1a1304936413049384161-13.35
CAediting_980496chr14_31014685_-ENSG00000101639.17ENST00000513432hsa-miR-624-3p13056143130561497mer-m81305613113056150146-17.79
CAediting_393chr1_1167164_+ENSG00000101639.17ENST00000513432hsa-miR-200b-3p13057693130576997mer-m81305767913057700155-13.18
CAediting_688080chr9_63819626_+ENSG00000101639.17ENST00000513432hsa-miR-4477b13069115130691217mer-m81306909913069122145-12.8
CAediting_393chr1_1167164_+ENSG00000101639.17ENST00000513432hsa-miR-200b-3p13105023131050297mer-m81310500813105030158-14.83
CAediting_393chr1_1167164_+ENSG00000101639.17ENST00000510237hsa-miR-200b-3p13105023131050297mer-m81310500813105030158-14.83
CAediting_393chr1_1167164_+ENSG00000101639.17ENST00000430049hsa-miR-200b-3p13105023131050297mer-m81310500813105030158-14.83
CAediting_604450chr7_133034877_-ENSG00000101639.17ENST00000513432hsa-miR-365413055822130558287mer-m81305581013055829143-20.2
CAediting_1229415chr17_67471547_+ENSG00000101639.17ENST00000513432hsa-miR-548aa13058467130584737mer-m81305845013058474141-8.68
CAediting_1160181chr17_7017644_-ENSG00000101639.17ENST00000513432hsa-miR-195-3p13058303130583097mer-m81305828913058310145-15.92
CAediting_1351755chr19_40282625_-ENSG00000101639.17ENST00000513432hsa-miR-64113058226130582327mer-m81305820613058233142-17.15
CAediting_1160181chr17_7017644_-ENSG00000101639.17ENST00000513432hsa-miR-195-3p13069154130691618mer-1a1306914013069161145-9.46
CAediting_396018chr5_1062918_-ENSG00000101639.17ENST00000513432hsa-miR-463513069116130691238mer-1a1306910713069123142-19.08
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000513432hsa-miR-6891-5p13057651130576588mer-1a1305764013057658145-26.26
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000513432hsa-miR-6891-5p13095576130955816mer1309556413095585144-26.22
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000430049hsa-miR-6891-5p13095576130955816mer1309556413095585144-26.22
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000508150hsa-miR-6891-5p13095576130955816mer1309556413095585144-26.22

check button RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.
CAeditom_IDPositionENSGENSTmiRNATargetscan startTargetscan endTargetscan scoreMiranda startMiranda endMiranda scoreMiranda energy
CAediting_846604chr11_93733708_-ENSG00000101639.17ENST00000513432hsa-miR-1304-3p13056039130560457mer-m81305602713056046148-15.75
CAediting_1524209chrX_134546392_-ENSG00000101639.17ENST00000513432hsa-miR-503-5p13056360130563667mer-m81305634113056367146-14.45
CAediting_393chr1_1167164_+ENSG00000101639.17ENST00000513432hsa-miR-200b-3p13058384130583907mer-m81305836913058391151-10.95
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000513432hsa-miR-6891-5p13095669130956746mer1309566313095680140-17.38
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000513432hsa-miR-6891-5p13095675130956806mer1309566313095680140-17.38
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000430049hsa-miR-6891-5p13095669130956746mer1309566313095680140-17.38
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000430049hsa-miR-6891-5p13095675130956806mer1309566313095680140-17.38
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000508150hsa-miR-6891-5p13095669130956746mer1309566313095681140-19.92
CAediting_468389chr6_31355314_-ENSG00000101639.17ENST00000508150hsa-miR-6891-5p13095675130956806mer1309566313095681140-19.92

check button Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for CEP192

check button - RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.
ENSTENST typeRNA structure without RNA A-to-I editing.RNA structure with RNA A-to-I editing.

check button RNA A-to-I editing in RNA structures for Minimum free energy (MFE).
CAeditom_IDENSTEditing_PositionMFE_withoneAIMFE_withoutAIMFE_withmultipleAI

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Relation with ADAR for CEP192

check button Correlation between ADAR gene expression and RNA editing frequency
CancerCAeditomIDpositionADAR1 (p-val)ADAR1 (coeff.)ADAR2 (p-val)ADAR2 (coeff.)ADAR3 (p-val)ADAR3 (coeff.)

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Relation with cancer stages for CEP192

check button Correlation between Cancer stages and RNA editing frequency
CancerStage_typeCAeditomIDpositionP-valCoeff.

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Relation with survival for CEP192

check button Correlation between RNA editing and survival
CancerCAeditomIDpositionKMpvalueCoxpvalueCoxHR

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RelatedDrugs for CEP192

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for CEP192

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease name# pubmedsSource