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Editing gene: C14orf119 (CAeditome ID:55017)

Gene summary for C14orf119

Gene summary

Gene information	Gene symbol	C14orf119
	Gene ID	55017
	Gene name	chromosome 14 open reading frame 119
	Synonyms	-
	Cytomap	14q11.2
	Type of gene	protein-coding
	Description	uncharacterized protein C14orf119My028 protein
	Modification date	20210518
	UniProtAcc	Q9NWQ9
	Context

Gene ontology of each this gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Gene	GO ID	GO term	PubMed ID
C14orf119	GO:0005739	Uncharacterized protein C14orf119	0000052
C14orf119	GO:0005829	Uncharacterized protein C14orf119	0000052

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RNA A-to-I events for C14orf119

RNA A-to-I editing events across TCGA 33 cancers data sets based on Ensembl gene isoform structure.

RNA editing frequencies across 33 cancers of gene: ENSG00000179933.5

RNA A-to-I editing events in Cancer.

CAediting_978300(23096253, +), CAediting_978301(23096262, +), CAediting_978302(23096267, +), CAediting_978303(23096270, +), CAediting_978304(23096294, +), CAediting_978305(23096297, +), CAediting_978306(23096302, +), CAediting_978307(23096307, +), CAediting_978308(23096318, +), CAediting_978309(23096341, +), CAediting_978310(23096355, +), CAediting_978311(23096356, +), CAediting_978312(23096357, +), CAediting_978313(23096358, +), CAediting_978314(23096364, +), CAediting_978315(23096369, +), CAediting_978316(23096372, +), CAediting_978317(23096396, +), CAediting_978318(23096404, +), CAediting_978319(23096408, +), CAediting_978320(23096415, +), CAediting_978321(23096421, +), CAediting_978322(23096425, +), CAediting_978323(23096430, +), CAediting_978324(23096440, +), CAediting_978325(23096444, +), CAediting_978326(23096464, +), CAediting_978327(23096497, +), CAediting_978328(23096676, +), CAediting_978329(23096694, +), CAediting_978330(23096706, +), CAediting_978331(23096710, +), CAediting_978332(23096713, +), CAediting_978333(23096716, +), CAediting_978334(23096718, +), CAediting_978335(23096738, +), CAediting_978336(23096739, +), CAediting_978337(23096742, +), CAediting_978338(23096743, +), CAediting_978339(23096751, +), CAediting_978340(23096760, +), CAediting_978341(23096767, +), CAediting_978342(23096798, +), CAediting_978343(23096811, +), CAediting_978344(23096816, +), CAediting_978345(23096839, +), CAediting_978346(23096846, +), CAediting_978347(23096868, +), CAediting_978348(23098695, +), CAediting_978349(23098726, +), CAediting_978350(23098742, +), CAediting_978351(23098743, +), CAediting_978352(23098748, +), CAediting_978353(23098755, +), CAediting_978354(23098761, +), CAediting_978355(23098762, +), CAediting_978356(23098765, +), CAediting_978357(23098779, +), CAediting_978358(23098788, +), CAediting_978359(23098791, +), CAediting_978360(23098795, +), CAediting_978361(23098803, +), CAediting_978362(23098834, +), CAediting_978363(23098899, +), CAediting_978364(23098913, +), CAediting_978365(23098928, +), CAediting_978366(23098942, +), CAediting_978367(23098958, +), CAediting_978368(23099584, +), CAediting_978369(23099634, +), CAediting_978370(23099639, +), CAediting_978371(23099659, +), CAediting_978372(23099663, +), CAediting_978373(23099678, +), CAediting_978374(23099689, +), CAediting_978375(23100018, +), CAediting_978376(23100022, +), CAediting_978377(23100042, +), CAediting_978378(23100050, +), CAediting_978379(23100108, +), CAediting_978380(23100127, +), CAediting_978381(23100133, +), CAediting_978382(23100139, +), CAediting_978383(23100143, +), CAediting_978384(23100150, +), CAediting_978385(23100156, +), CAediting_978386(23100165, +), CAediting_978387(23100166, +), CAediting_978388(23100169, +), CAediting_978389(23100179, +), CAediting_978390(23100194, +), CAediting_978391(23100196, +), CAediting_978392(23100200, +), CAediting_978393(23100207, +), CAediting_978394(23100210, +), CAediting_978395(23100225, +), CAediting_978396(23100237, +),

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RNA editing positional annotations for C14orf119 using Annovar

Protein coding RNA editing(s).

CAeditome ID

Position

Variant type

ENST

NTchange

AAchange

SIFT_score

Polyphen2_HVAR_score

PROVEAN_pred

Gene structure information of RNA editing(s).

CAeditome ID	Position	Variant type
CAediting_978300	chr14_23096253_+	intronic
CAediting_978301	chr14_23096262_+	intronic
CAediting_978302	chr14_23096267_+	intronic
CAediting_978303	chr14_23096270_+	intronic
CAediting_978304	chr14_23096294_+	intronic
CAediting_978305	chr14_23096297_+	intronic
CAediting_978306	chr14_23096302_+	intronic
CAediting_978307	chr14_23096307_+	intronic
CAediting_978308	chr14_23096318_+	intronic
CAediting_978309	chr14_23096341_+	intronic
CAediting_978310	chr14_23096355_+	intronic
CAediting_978311	chr14_23096356_+	intronic
CAediting_978312	chr14_23096357_+	intronic
CAediting_978313	chr14_23096358_+	intronic
CAediting_978314	chr14_23096364_+	intronic
CAediting_978315	chr14_23096369_+	intronic
CAediting_978316	chr14_23096372_+	intronic
CAediting_978317	chr14_23096396_+	intronic
CAediting_978318	chr14_23096404_+	intronic
CAediting_978319	chr14_23096408_+	intronic
CAediting_978320	chr14_23096415_+	intronic
CAediting_978321	chr14_23096421_+	intronic
CAediting_978322	chr14_23096425_+	intronic
CAediting_978323	chr14_23096430_+	intronic
CAediting_978324	chr14_23096440_+	intronic
CAediting_978325	chr14_23096444_+	intronic
CAediting_978326	chr14_23096464_+	intronic
CAediting_978327	chr14_23096497_+	intronic
CAediting_978328	chr14_23096676_+	intronic
CAediting_978329	chr14_23096694_+	intronic
CAediting_978330	chr14_23096706_+	intronic
CAediting_978331	chr14_23096710_+	intronic
CAediting_978332	chr14_23096713_+	intronic
CAediting_978333	chr14_23096716_+	intronic
CAediting_978334	chr14_23096718_+	intronic
CAediting_978335	chr14_23096738_+	intronic
CAediting_978336	chr14_23096739_+	intronic
CAediting_978337	chr14_23096742_+	intronic
CAediting_978338	chr14_23096743_+	intronic
CAediting_978339	chr14_23096751_+	intronic
CAediting_978340	chr14_23096760_+	intronic
CAediting_978341	chr14_23096767_+	intronic
CAediting_978342	chr14_23096798_+	intronic
CAediting_978343	chr14_23096811_+	intronic
CAediting_978344	chr14_23096816_+	intronic
CAediting_978345	chr14_23096839_+	intronic
CAediting_978346	chr14_23096846_+	intronic
CAediting_978347	chr14_23096868_+	intronic
CAediting_978348	chr14_23098695_+	UTR3
CAediting_978349	chr14_23098726_+	UTR3
CAediting_978350	chr14_23098742_+	UTR3
CAediting_978351	chr14_23098743_+	UTR3
CAediting_978352	chr14_23098748_+	UTR3
CAediting_978353	chr14_23098755_+	UTR3
CAediting_978354	chr14_23098761_+	UTR3
CAediting_978355	chr14_23098762_+	UTR3
CAediting_978356	chr14_23098765_+	UTR3
CAediting_978357	chr14_23098779_+	UTR3
CAediting_978358	chr14_23098788_+	UTR3
CAediting_978359	chr14_23098791_+	UTR3
CAediting_978360	chr14_23098795_+	UTR3
CAediting_978361	chr14_23098803_+	UTR3
CAediting_978362	chr14_23098834_+	UTR3
CAediting_978363	chr14_23098899_+	UTR3
CAediting_978364	chr14_23098913_+	UTR3
CAediting_978365	chr14_23098928_+	UTR3
CAediting_978366	chr14_23098942_+	UTR3
CAediting_978367	chr14_23098958_+	UTR3
CAediting_978368	chr14_23099584_+	UTR3
CAediting_978369	chr14_23099634_+	UTR3
CAediting_978370	chr14_23099639_+	UTR3
CAediting_978371	chr14_23099659_+	UTR3
CAediting_978372	chr14_23099663_+	UTR3
CAediting_978373	chr14_23099678_+	UTR3
CAediting_978374	chr14_23099689_+	UTR3
CAediting_978375	chr14_23100018_+	UTR3
CAediting_978376	chr14_23100022_+	UTR3
CAediting_978377	chr14_23100042_+	UTR3
CAediting_978378	chr14_23100050_+	UTR3
CAediting_978379	chr14_23100108_+	UTR3
CAediting_978380	chr14_23100127_+	UTR3
CAediting_978381	chr14_23100133_+	UTR3
CAediting_978382	chr14_23100139_+	UTR3
CAediting_978383	chr14_23100143_+	UTR3
CAediting_978384	chr14_23100150_+	UTR3
CAediting_978385	chr14_23100156_+	UTR3
CAediting_978386	chr14_23100165_+	UTR3
CAediting_978387	chr14_23100166_+	UTR3
CAediting_978388	chr14_23100169_+	UTR3
CAediting_978389	chr14_23100179_+	UTR3
CAediting_978390	chr14_23100194_+	UTR3
CAediting_978391	chr14_23100196_+	UTR3
CAediting_978392	chr14_23100200_+	UTR3
CAediting_978393	chr14_23100207_+	UTR3
CAediting_978394	chr14_23100210_+	UTR3
CAediting_978395	chr14_23100225_+	UTR3
CAediting_978396	chr14_23100237_+	UTR3

Repat-regional RNA editing(s).

CAeditome ID	Position	Repeat family	Repeat sub family	Repeat name
CAediting_978300	chr14_23096253_+	SINE	Alu	AluSz
CAediting_978301	chr14_23096262_+	SINE	Alu	AluSz
CAediting_978302	chr14_23096267_+	SINE	Alu	AluSz
CAediting_978303	chr14_23096270_+	SINE	Alu	AluSz
CAediting_978304	chr14_23096294_+	SINE	Alu	AluSz
CAediting_978305	chr14_23096297_+	SINE	Alu	AluSz
CAediting_978306	chr14_23096302_+	SINE	Alu	AluSz
CAediting_978307	chr14_23096307_+	SINE	Alu	AluSz
CAediting_978308	chr14_23096318_+	SINE	Alu	AluSz
CAediting_978309	chr14_23096341_+	SINE	Alu	AluSz
CAediting_978310	chr14_23096355_+	SINE	Alu	AluSz
CAediting_978311	chr14_23096356_+	SINE	Alu	AluSz
CAediting_978312	chr14_23096357_+	SINE	Alu	AluSz
CAediting_978313	chr14_23096358_+	SINE	Alu	AluSz
CAediting_978314	chr14_23096364_+	SINE	Alu	AluSz
CAediting_978315	chr14_23096369_+	SINE	Alu	AluSz
CAediting_978316	chr14_23096372_+	SINE	Alu	AluSz
CAediting_978317	chr14_23096396_+	SINE	Alu	AluSz
CAediting_978318	chr14_23096404_+	SINE	Alu	AluSz
CAediting_978319	chr14_23096408_+	SINE	Alu	AluSz
CAediting_978320	chr14_23096415_+	SINE	Alu	AluSz
CAediting_978321	chr14_23096421_+	SINE	Alu	AluSz
CAediting_978322	chr14_23096425_+	SINE	Alu	AluSz
CAediting_978323	chr14_23096430_+	SINE	Alu	AluSz
CAediting_978324	chr14_23096440_+	SINE	Alu	AluSz
CAediting_978325	chr14_23096444_+	SINE	Alu	AluSz
CAediting_978326	chr14_23096464_+	SINE	Alu	AluSz
CAediting_978327	chr14_23096497_+	SINE	Alu	AluSz
CAediting_978328	chr14_23096676_+	SINE	Alu	AluJb
CAediting_978329	chr14_23096694_+	SINE	Alu	AluJb
CAediting_978330	chr14_23096706_+	SINE	Alu	AluJb
CAediting_978331	chr14_23096710_+	SINE	Alu	AluJb
CAediting_978332	chr14_23096713_+	SINE	Alu	AluJb
CAediting_978333	chr14_23096716_+	SINE	Alu	AluJb
CAediting_978334	chr14_23096718_+	SINE	Alu	AluJb
CAediting_978335	chr14_23096738_+	SINE	Alu	AluJb
CAediting_978336	chr14_23096739_+	SINE	Alu	AluJb
CAediting_978337	chr14_23096742_+	SINE	Alu	AluJb
CAediting_978338	chr14_23096743_+	SINE	Alu	AluJb
CAediting_978339	chr14_23096751_+	SINE	Alu	AluJb
CAediting_978340	chr14_23096760_+	SINE	Alu	AluJb
CAediting_978341	chr14_23096767_+	SINE	Alu	AluJb
CAediting_978342	chr14_23096798_+	SINE	Alu	AluJb
CAediting_978343	chr14_23096811_+	SINE	Alu	AluJb
CAediting_978344	chr14_23096816_+	SINE	Alu	AluJb
CAediting_978345	chr14_23096839_+	SINE	Alu	AluJb
CAediting_978346	chr14_23096846_+	SINE	Alu	AluJb
CAediting_978347	chr14_23096868_+	SINE	Alu	AluJb
CAediting_978348	chr14_23098695_+	SINE	Alu	AluJr4
CAediting_978349	chr14_23098726_+	SINE	Alu	AluJr4
CAediting_978350	chr14_23098742_+	SINE	Alu	AluJr4
CAediting_978351	chr14_23098743_+	SINE	Alu	AluJr4
CAediting_978352	chr14_23098748_+	SINE	Alu	AluJr4
CAediting_978353	chr14_23098755_+	SINE	Alu	AluJr4
CAediting_978354	chr14_23098761_+	SINE	Alu	AluJr4
CAediting_978355	chr14_23098762_+	SINE	Alu	AluJr4
CAediting_978356	chr14_23098765_+	SINE	Alu	AluJr4
CAediting_978357	chr14_23098779_+	SINE	Alu	AluJr4
CAediting_978358	chr14_23098788_+	SINE	Alu	AluJr4
CAediting_978359	chr14_23098791_+	SINE	Alu	AluJr4
CAediting_978360	chr14_23098795_+	SINE	Alu	AluJr4
CAediting_978361	chr14_23098803_+	SINE	Alu	AluJr4
CAediting_978362	chr14_23098834_+	SINE	Alu	AluJr4
CAediting_978363	chr14_23098899_+	SINE	Alu	AluJr4
CAediting_978364	chr14_23098913_+	SINE	Alu	AluJr4
CAediting_978365	chr14_23098928_+	SINE	Alu	AluJr4
CAediting_978366	chr14_23098942_+	SINE	Alu	AluJr4
CAediting_978367	chr14_23098958_+	SINE	Alu	AluJr4
CAediting_978368	chr14_23099584_+	SINE	Alu	AluSx3
CAediting_978369	chr14_23099634_+	SINE	Alu	AluSx3
CAediting_978370	chr14_23099639_+	SINE	Alu	AluSx3
CAediting_978371	chr14_23099659_+	SINE	Alu	AluSx3
CAediting_978372	chr14_23099663_+	SINE	Alu	AluSx3
CAediting_978373	chr14_23099678_+	SINE	Alu	AluSx3
CAediting_978374	chr14_23099689_+	SINE	Alu	AluSx3
CAediting_978375	chr14_23100018_+	SINE	Alu	AluJb
CAediting_978376	chr14_23100022_+	SINE	Alu	AluJb
CAediting_978377	chr14_23100042_+	SINE	Alu	AluJb
CAediting_978378	chr14_23100050_+	SINE	Alu	AluJb
CAediting_978379	chr14_23100108_+	SINE	Alu	AluJb
CAediting_978380	chr14_23100127_+	SINE	Alu	AluJb
CAediting_978381	chr14_23100133_+	SINE	Alu	AluJb
CAediting_978382	chr14_23100139_+	SINE	Alu	AluJb
CAediting_978383	chr14_23100143_+	SINE	Alu	AluJb
CAediting_978384	chr14_23100150_+	SINE	Alu	AluJb
CAediting_978385	chr14_23100156_+	SINE	Alu	AluJb
CAediting_978386	chr14_23100165_+	SINE	Alu	AluJb
CAediting_978387	chr14_23100166_+	SINE	Alu	AluJb
CAediting_978388	chr14_23100169_+	SINE	Alu	AluJb
CAediting_978389	chr14_23100179_+	SINE	Alu	AluJb
CAediting_978390	chr14_23100194_+	SINE	Alu	AluJb
CAediting_978391	chr14_23100196_+	SINE	Alu	AluJb
CAediting_978392	chr14_23100200_+	SINE	Alu	AluJb
CAediting_978393	chr14_23100207_+	SINE	Alu	AluJb
CAediting_978394	chr14_23100210_+	SINE	Alu	AluJb
CAediting_978395	chr14_23100225_+	SINE	Alu	AluJb
CAediting_978396	chr14_23100237_+	SINE	Alu	AluJb

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RNA A-to-I editing events in the alternative splicing sites for C14orf119

RNA A-to-I editing(s) in the alternative splicing sites.

AStype	CAeditomID	Editing position	AS position	AS direction	Exonic location	Wildtype sequence	Wildtype splicing strength	RNA edited sequence	RNA edited splicing strength
IR	CAediting_978334	chr14_23096718_+	23096717:23096725	5SS	2+0i	CAGGTAGGC	9.88	CGGGTAGGC	7.5

Differential percent of spliced in (PSI) between RNA A-to-I edited and non-edited samples for ENSG00000179933.5.C14orf119.

Correlation between RNA A-to-I editing and PSI for ENSG00000179933.5.C14orf119.

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Differntial gene expression between RNA A-to-I edited versus non-edited samples for C14orf119

Differential gene expressions between RNA A-to-I edited and non-edited tumor samples.
* The grey color means N/A.

Correlation between RNA A-to-I editing and gene expression.

- Differentially expressed gene between RNA A-to-I edited samples versus non-edited samples.
* Click on the image to enlarge it in a new window.

BRCA.CAediting_978391.ENSG00000179933.C14orf119.png
Soverview

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Protein coding region RNA A-to-I editings for C14orf119

- Lollipop plot for RNA A-to-I editings across protein structure.
* Click on the image to enlarge it in a new window.

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The effects of the RNA editing to the miRNA binding sites for C14orf119

**If you are searching a miRNA gene with RNA editing events in its seed regions, please see the search pages of miRNA targets to discover the effects of this RNA editing event to miRNA regulations. For more information, please check the files in the Download page.

RNA A-to-I editing in the 3'-UTR regions of mRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in the 3'-UTR regions of mRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA gained miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in lncRNA lost miRNA binding sites.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to lncRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs gained binding to the 3'-UTR region of mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

RNA A-to-I editing in miRNAs lost binding to the 3'-UTR mRNA.

CAeditom_ID

Position

ENSG

ENST

miRNA

Targetscan start

Targetscan end

Targetscan score

Miranda start

Miranda end

Miranda score

Miranda energy

Differentially expressed gene-miRNA network

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The effects of the RNA editing to the stability of the RNA structures for C14orf119

- RNA A-to-I editing in mRNA.
* Click on the image to enlarge it in a new window.

ENST

ENST type

RNA structure without RNA A-to-I editing.

RNA structure with RNA A-to-I editing.

RNA A-to-I editing in RNA structures for Minimum free energy (MFE).

CAeditom_ID

ENST

Editing_Position

MFE_withoneAI

MFE_withoutAI

MFE_withmultipleAI

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Relation with ADAR for C14orf119

Correlation between ADAR gene expression and RNA editing frequency

Cancer	CAeditomID	position	ADAR1 (p-val)	ADAR1 (coeff.)	ADAR2 (p-val)	ADAR2 (coeff.)	ADAR3 (p-val)	ADAR3 (coeff.)
ESCA	CAediting_978344	chr14_23096816_+	0.0442062853098209	0.217550772918652	.	.	.	.
BRCA	CAediting_978348	chr14_23098695_+	0.0176059772840449	0.204805368996739	.	.	.	.
OV	CAediting_978350	chr14_23098742_+	0.0137604183210385	0.210806076702367	.	.	.	.
THCA	CAediting_978356	chr14_23098765_+	0.0108665334557653	0.32137438190509	.	.	.	.
BRCA	CAediting_978360	chr14_23098795_+	0.0161785317424092	0.225811000590273	.	.	.	.
OV	CAediting_978360	chr14_23098795_+	0.00160454671194395	0.283848261552996	.	.	0.00319207497902932	0.265970494196126
BRCA	CAediting_978391	chr14_23100196_+	0.0381689518594018	0.22267477458976	.	.	.	.

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Relation with cancer stages for C14orf119

Correlation between Cancer stages and RNA editing frequency

Cancer	Stage_type	CAeditomID	position	P-val	Coeff.
THCA	pathologic_stage	CAediting_978350	chr14_23098742_+	0.0303045105790661	0.248671382469624

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Relation with survival for C14orf119

Correlation between RNA editing and survival

Cancer

CAeditomID

position

KMpvalue

Coxpvalue

CoxHR

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RelatedDrugs for C14orf119

Approved drugs targeting this gene.
(DrugBank Version 5.1.8 2021-01-03)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for C14orf119

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

# pubmeds

Source

	Gene summary
	RNA A-to-I events
	Differntial gene expression between RNA A-to-I edited tumor samples versus normal samples
	Protein coding region RNA A-to-I editings
	The effects of the RNA editing to the miRNA binding sites
	The effects of the RNA editing to the stability of the RNA structures
	Relation with ADAR
	Relation with cancer stages
	Relation with survival state
	Related drugs with this gene
	Related diseases with this gene